EP3429601A4 - Chitosan hydrogels for accelerating involution and preventing infection of the mammary gland at drying-off - Google Patents

Chitosan hydrogels for accelerating involution and preventing infection of the mammary gland at drying-off Download PDF

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Publication number
EP3429601A4
EP3429601A4 EP17765617.0A EP17765617A EP3429601A4 EP 3429601 A4 EP3429601 A4 EP 3429601A4 EP 17765617 A EP17765617 A EP 17765617A EP 3429601 A4 EP3429601 A4 EP 3429601A4
Authority
EP
European Patent Office
Prior art keywords
drying
mammary gland
preventing infection
chitosan hydrogels
involution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP17765617.0A
Other languages
German (de)
French (fr)
Other versions
EP3429601A1 (en
Inventor
Pierre Lacasse
Samuel LANCTÔT
Patrick Fustier
Ali R. TAHERIAN
Barbara BISAKOWSKI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Agriculture and Agri Food Canada AAFC
Original Assignee
Agriculture and Agri Food Canada AAFC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agriculture and Agri Food Canada AAFC filed Critical Agriculture and Agri Food Canada AAFC
Publication of EP3429601A1 publication Critical patent/EP3429601A1/en
Publication of EP3429601A4 publication Critical patent/EP3429601A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/722—Chitin, chitosan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0041—Mammary glands, e.g. breasts, udder; Intramammary administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/075—Macromolecular gels
EP17765617.0A 2016-03-18 2017-03-16 Chitosan hydrogels for accelerating involution and preventing infection of the mammary gland at drying-off Withdrawn EP3429601A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662310025P 2016-03-18 2016-03-18
PCT/CA2017/050339 WO2017156632A1 (en) 2016-03-18 2017-03-16 Chitosan hydrogels for accelerating involution and preventing infection of the mammary gland at drying-off

Publications (2)

Publication Number Publication Date
EP3429601A1 EP3429601A1 (en) 2019-01-23
EP3429601A4 true EP3429601A4 (en) 2019-11-27

Family

ID=59850126

Family Applications (1)

Application Number Title Priority Date Filing Date
EP17765617.0A Withdrawn EP3429601A4 (en) 2016-03-18 2017-03-16 Chitosan hydrogels for accelerating involution and preventing infection of the mammary gland at drying-off

Country Status (11)

Country Link
US (1) US10828319B2 (en)
EP (1) EP3429601A4 (en)
CN (1) CN109310705A (en)
AU (1) AU2017233727A1 (en)
BR (1) BR112018068794A2 (en)
CA (1) CA3015846A1 (en)
CL (1) CL2018002562A1 (en)
CO (1) CO2018011133A2 (en)
MX (1) MX2018011350A (en)
RU (1) RU2018135961A (en)
WO (1) WO2017156632A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018195237A1 (en) * 2017-04-20 2018-10-25 Zoetis Services Llc Veterinary compositions for use in treating mastitis, and associated methods
UY38969A (en) 2019-11-28 2021-05-31 Boehringer Ingelheim Vetmedica Gmbh USE OF SGLT-2 INHIBITORS IN DRYING NON-HUMAN MAMMALS
CN111840212B (en) * 2020-06-18 2023-07-21 余祖功 Nipple blocking agent for non-human animals and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2212300A1 (en) * 1997-08-04 1999-02-04 Abdellatif Chenite In vitro or in vivo gelfying chitosan and therapeutic uses thereof
US20100151029A1 (en) * 2004-02-27 2010-06-17 Hydromer, Inc. Anti-infectious hydrogel compositions
WO2017079216A1 (en) * 2015-11-03 2017-05-11 Zoetis Services Llc Sol-gel polymer composites and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7098194B2 (en) 2001-11-15 2006-08-29 Biosyntech Canada, Inc. Composition and method to homogeneously modify or cross-link chitosan under neutral conditions
WO2015093937A1 (en) * 2013-12-19 2015-06-25 N.V. Nutricia Lactobacillus salivarius for the treatment of mastitis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2212300A1 (en) * 1997-08-04 1999-02-04 Abdellatif Chenite In vitro or in vivo gelfying chitosan and therapeutic uses thereof
US20100151029A1 (en) * 2004-02-27 2010-06-17 Hydromer, Inc. Anti-infectious hydrogel compositions
WO2017079216A1 (en) * 2015-11-03 2017-05-11 Zoetis Services Llc Sol-gel polymer composites and uses thereof

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BIBIANA ELISABET DALLARD ET AL: "The effect of a single intramammary infusion of a biological response modifier in cows at drying off", VETERINARY RESEARCH COMMUNICATIONS ; AN INTERNATIONAL JOURNAL PUBLISHING TOPICAL REVIEWS AND RESEARCH ARTICLES ON ALL ASPECTS OF THE VETERINARY SCIENCES, KLUWER ACADEMIC PUBLISHERS, DO, vol. 34, no. 6, 2 July 2010 (2010-07-02), pages 519 - 532, XP019832144, ISSN: 1573-7446 *
CHENITE A ET AL: "Rheological characterisation of thermogelling chitosan/glycerol-phosphate solutions", CARBOHYDRATE POLYMERS, APPLIED SCIENCE PUBLISHERS, LTD. BARKING, GB, vol. 46, no. 1, 1 September 2001 (2001-09-01), pages 39 - 47, XP004247270, ISSN: 0144-8617, DOI: 10.1016/S0144-8617(00)00281-2 *
JIN-SAN MOON ET AL: "The antibacterial and immunostimulative effect of chitosan-oligosaccharides against infection by Staphylococcus aureus isolated from bovine mastitis", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, SPRINGER, BERLIN, DE, vol. 75, no. 5, 15 March 2007 (2007-03-15), pages 989 - 998, XP019513720, ISSN: 1432-0614, DOI: 10.1007/S00253-007-0898-8 *
LANCTÔT S ET AL: "Effect of intramammary infusion of chitosan hydrogels at drying-off on bovine mammary gland involution", JOURNAL OF DAIRY SCIENCE, vol. 100, no. 3, 18 January 2017 (2017-01-18), pages 2269 - 2281, XP029924562, ISSN: 0022-0302, DOI: 10.3168/JDS.2016-12087 *
See also references of WO2017156632A1 *
ZECCONI A ET AL: "Efficacy of a Biological Response Modifier in Preventing Staphylococcus aureus Intramammary Infections After Calving", JOURNAL OF DAIRY SCIENCE, AMERICAN DAIRY SCIENCE ASSOCIATION, US, vol. 82, no. 10, 1 October 1999 (1999-10-01), pages 2101 - 2107, XP026993287, ISSN: 0022-0302, [retrieved on 19991001] *

Also Published As

Publication number Publication date
US10828319B2 (en) 2020-11-10
CO2018011133A2 (en) 2018-10-31
MX2018011350A (en) 2019-06-06
CL2018002562A1 (en) 2019-02-15
US20190060352A1 (en) 2019-02-28
AU2017233727A1 (en) 2018-09-13
CA3015846A1 (en) 2017-09-21
EP3429601A1 (en) 2019-01-23
RU2018135961A (en) 2020-04-20
WO2017156632A1 (en) 2017-09-21
CN109310705A (en) 2019-02-05
BR112018068794A2 (en) 2019-04-09

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EP3429601A4 (en) Chitosan hydrogels for accelerating involution and preventing infection of the mammary gland at drying-off

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