EP3377610A4 - Ratiometric biosensors and non-geometrically modulated fret - Google Patents
Ratiometric biosensors and non-geometrically modulated fret Download PDFInfo
- Publication number
- EP3377610A4 EP3377610A4 EP16867307.7A EP16867307A EP3377610A4 EP 3377610 A4 EP3377610 A4 EP 3377610A4 EP 16867307 A EP16867307 A EP 16867307A EP 3377610 A4 EP3377610 A4 EP 3377610A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- fret
- geometrically modulated
- ratiometric
- biosensors
- ratiometric biosensors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Optical Transform (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562257863P | 2015-11-20 | 2015-11-20 | |
US201562257859P | 2015-11-20 | 2015-11-20 | |
US201562257796P | 2015-11-20 | 2015-11-20 | |
US201562257850P | 2015-11-20 | 2015-11-20 | |
PCT/US2016/062958 WO2017087912A2 (en) | 2015-11-20 | 2016-11-19 | Ratiometric biosensors and non-geometrically modulated fret |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3377610A2 EP3377610A2 (en) | 2018-09-26 |
EP3377610A4 true EP3377610A4 (en) | 2019-10-16 |
Family
ID=58719234
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP16867307.7A Withdrawn EP3377610A4 (en) | 2015-11-20 | 2016-11-19 | Ratiometric biosensors and non-geometrically modulated fret |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP3377610A4 (en) |
CA (1) | CA3005883A1 (en) |
WO (1) | WO2017087912A2 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2013204332B2 (en) | 2012-04-16 | 2015-07-16 | Commonwealth Scientific And Industrial Research Organisation | Methods and systems for detecting an analyte or classifying a sample |
US11906524B2 (en) | 2015-11-20 | 2024-02-20 | Duke University | Urea biosensors and uses thereof |
CA3005892A1 (en) | 2015-11-20 | 2017-05-26 | Duke University | Lactate biosensors and uses thereof |
CA3005890A1 (en) | 2015-11-20 | 2017-05-26 | Duke University | Thermostable glucose biosensors and uses thereof |
JP2020510406A (en) | 2016-11-14 | 2020-04-09 | コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガナイゼーション | Protease sensor molecule |
US11667900B2 (en) | 2017-07-14 | 2023-06-06 | The Regents Of The University Of California | Compositions and methods for enhancing macrophage-mediated antibody guided cancer cell or tumor eradication |
JP7246372B2 (en) | 2017-08-08 | 2023-03-27 | コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガナイゼーション | carb sensor |
CN110596072B (en) * | 2019-10-29 | 2022-05-13 | 陕西师范大学 | Ratio type fluorescent paper chip based on polyester fiber film, preparation method and application |
CN117795312A (en) | 2021-07-01 | 2024-03-29 | 微量热技术有限公司 | Method and apparatus for characterizing fluorescent particles by ratio |
CA3237959A1 (en) * | 2021-12-07 | 2023-06-15 | Megan PETTYGROVE | Fluorescence detection of sulfite in water treatment applications |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6900304B2 (en) * | 1996-01-31 | 2005-05-31 | The Regents Of The University Of California | Emission ratiometric indicators of phosphorylation |
US6277627B1 (en) * | 1997-12-31 | 2001-08-21 | Duke University | Biosensor |
US6432723B1 (en) * | 1999-01-22 | 2002-08-13 | Clinical Micro Sensors, Inc. | Biosensors utilizing ligand induced conformation changes |
EP1335984A1 (en) * | 2000-11-10 | 2003-08-20 | Biosensor APS | Determination of hydrophobic coenzyme a esters and other lipids using a biosensor comprising a modified coenzyme a- and acyl-coa binding protein (acbp) |
KR20070043768A (en) * | 2004-07-01 | 2007-04-25 | 비보메디칼 인코포레이티드 | Non-invasive glucose measurement |
US8697388B2 (en) * | 2007-02-08 | 2014-04-15 | U.S. Department Of Energy | Heavy metal biosensor |
WO2009023153A1 (en) * | 2007-08-10 | 2009-02-19 | Carnegie Institution Of Washington | Methods of using ret nanosensors |
US8222047B2 (en) * | 2008-09-23 | 2012-07-17 | Quanterix Corporation | Ultra-sensitive detection of molecules on single molecule arrays |
-
2016
- 2016-11-19 CA CA3005883A patent/CA3005883A1/en not_active Abandoned
- 2016-11-19 WO PCT/US2016/062958 patent/WO2017087912A2/en active Application Filing
- 2016-11-19 EP EP16867307.7A patent/EP3377610A4/en not_active Withdrawn
Non-Patent Citations (3)
Title |
---|
KARLSTROEM A ET AL: "Dual labeling of a binding protein allows for specific fluorescence detection of native protein", ANALYTICAL BIOCHEMISTRY, ELSEVIER, AMSTERDAM, NL, vol. 295, no. 1, 1 August 2001 (2001-08-01), pages 22 - 30, XP002224547, ISSN: 0003-2697, DOI: 10.1006/ABIO.2001.5186 * |
KHAN F ET AL: "Fluorescence-based sensing of glucose using engineered glucose/galactose-binding protein: A comparison of fluorescence resonance energy transfer and environmentally sensitive dye labelling strategies", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ELSEVIER, AMSTERDAM, NL, vol. 365, no. 1, 4 January 2008 (2008-01-04), pages 102 - 106, XP022680927, ISSN: 0006-291X, [retrieved on 20071030], DOI: 10.1016/J.BBRC.2007.10.129 * |
SMITH J J ET AL: "ORTHOGONAL SITE-SPECIFIC PROTEIN MODIFICATION BY ENGINEERING REVERSIBLE THIOL PROTECTION MECHANISMS", PROTEIN SCI, WILEY, US, vol. 14, no. 1, 1 January 2005 (2005-01-01), pages 64 - 73, XP008047394, ISSN: 0961-8368, DOI: 10.1110/PS.04965405 * |
Also Published As
Publication number | Publication date |
---|---|
WO2017087912A2 (en) | 2017-05-26 |
WO2017087912A3 (en) | 2017-07-06 |
CA3005883A1 (en) | 2017-05-26 |
EP3377610A2 (en) | 2018-09-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
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STAA | Information on the status of an ep patent application or granted ep patent |
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17P | Request for examination filed |
Effective date: 20180620 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
AX | Request for extension of the european patent |
Extension state: BA ME |
|
DAV | Request for validation of the european patent (deleted) | ||
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20190918 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: G01N 33/543 20060101ALI20190912BHEP Ipc: G01N 21/64 20060101ALI20190912BHEP Ipc: G01N 33/58 20060101ALI20190912BHEP Ipc: C07K 14/195 20060101ALI20190912BHEP Ipc: G01N 33/53 20060101AFI20190912BHEP Ipc: G01N 33/533 20060101ALI20190912BHEP Ipc: G01N 33/84 20060101ALI20190912BHEP |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |
|
17Q | First examination report despatched |
Effective date: 20210215 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20210626 |