EP3347142B1 - Device and process for separating particle fragments from said particles - Google Patents

Device and process for separating particle fragments from said particles Download PDF

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Publication number
EP3347142B1
EP3347142B1 EP16767179.1A EP16767179A EP3347142B1 EP 3347142 B1 EP3347142 B1 EP 3347142B1 EP 16767179 A EP16767179 A EP 16767179A EP 3347142 B1 EP3347142 B1 EP 3347142B1
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EP
European Patent Office
Prior art keywords
floor
particles
ceiling
fragments
orifices
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EP16767179.1A
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German (de)
French (fr)
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EP3347142A1 (en
Inventor
Martial Dollinger
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PHARMA Tech SA
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PHARMA Tech SA
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/074Filling capsules; Related operations
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B07SEPARATING SOLIDS FROM SOLIDS; SORTING
    • B07BSEPARATING SOLIDS FROM SOLIDS BY SIEVING, SCREENING, SIFTING OR BY USING GAS CURRENTS; SEPARATING BY OTHER DRY METHODS APPLICABLE TO BULK MATERIAL, e.g. LOOSE ARTICLES FIT TO BE HANDLED LIKE BULK MATERIAL
    • B07B1/00Sieving, screening, sifting, or sorting solid materials using networks, gratings, grids, or the like
    • B07B1/46Constructional details of screens in general; Cleaning or heating of screens
    • B07B1/4609Constructional details of screens in general; Cleaning or heating of screens constructional details of screening surfaces or meshes
    • B07B1/469Perforated sheet-like material
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B07SEPARATING SOLIDS FROM SOLIDS; SORTING
    • B07BSEPARATING SOLIDS FROM SOLIDS BY SIEVING, SCREENING, SIFTING OR BY USING GAS CURRENTS; SEPARATING BY OTHER DRY METHODS APPLICABLE TO BULK MATERIAL, e.g. LOOSE ARTICLES FIT TO BE HANDLED LIKE BULK MATERIAL
    • B07B1/00Sieving, screening, sifting, or sorting solid materials using networks, gratings, grids, or the like
    • B07B1/46Constructional details of screens in general; Cleaning or heating of screens
    • B07B1/50Cleaning
    • B07B1/55Cleaning with fluid jets
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B07SEPARATING SOLIDS FROM SOLIDS; SORTING
    • B07BSEPARATING SOLIDS FROM SOLIDS BY SIEVING, SCREENING, SIFTING OR BY USING GAS CURRENTS; SEPARATING BY OTHER DRY METHODS APPLICABLE TO BULK MATERIAL, e.g. LOOSE ARTICLES FIT TO BE HANDLED LIKE BULK MATERIAL
    • B07B13/00Grading or sorting solid materials by dry methods, not otherwise provided for; Sorting articles otherwise than by indirectly controlled devices
    • B07B13/04Grading or sorting solid materials by dry methods, not otherwise provided for; Sorting articles otherwise than by indirectly controlled devices according to size

Definitions

  • the present invention relates to a device for separating particle cassons from said particles and a method of implementing this device.
  • Such devices are used in various industries when it is a question of separating particles of a first form, of cassons of such particles to which they are mixed, such cassons being able in particular to result from the breaking of said particles during their process of manufacturing.
  • these particles consist of tablets or capsules and it is important that only whole tablets or capsules result in the packaging chain of the latter in containers containing a certain number of these tablets or capsules. capsules to be placed on the market.
  • Such a device generally comprises a floor arranged to receive particles of a specific shape and cassons of such particles, connected to a first means arranged to animate said floor of a vibratory movement so that the particles and cassons in question move on the floor in a direction determined by the type of vibratory movement that is printed to it, said floor being pierced with orifices of a predetermined shape depending on the shape of the particles, to let through the said orifices the cassons of such particles but not the particles themselves.
  • the two dimensions (length, width) of such an orifice may be slightly greater than two of the three dimensions (length, width, height) of a particle, but smaller than its third dimension.
  • a particle casson whose third dimension is reduced relative to that of a whole particle can to fall easily into the hole in question whereas an entire particle could only fall by an axis of symmetry orthogonal to said third dimension.
  • the fraction of whole particles having nevertheless passed through the floor of the device by some of its orifices may be recovered upstream by appropriate means.
  • Such a device also generally comprises a ceiling arranged substantially parallel to the floor of the device.
  • the document FR2841161 for example, describes such a device, according to the preamble of claim 1, and, implicitly, a method according to the preamble of claim 12.
  • a problem caused by such devices is that it happens that cassons whose third dimension is greater than or equal to at least one of the two dimensions of the openings of the floor of the device are stuck in these orifices and thus obstruct them .
  • cassons whose third dimension is greater than or equal to at least one of the two dimensions of the openings of the floor of the device are stuck in these orifices and thus obstruct them .
  • more and more orifices may be obstructed in this way, which reduces the separation efficiency of this device accordingly.
  • the invention solves the aforementioned problem by providing a device of the type described above but which further comprises second means arranged to move the ceiling of the device between a first position and a second position in which it is in contact with the device. floor so that particles of particles stuck in said orifices are expelled, according to claim 1.
  • the ceiling called plate, is used to control the position of particles, but remains at a fixed distance compared to the floor.
  • the device described in this document does not allow to unclog the holes.
  • the first means is a means of vibration.
  • the first means is mechanically connected to the floor.
  • the floor and the ceiling are mechanically coupled.
  • the second means is mechanically coupled to the ceiling.
  • a device I for separating particle p particles of a first form said particles comprising a floor 1 arranged to receive said particles and said cassons, connected to a first means 2 arranged to animate said floor with a vibratory movement, said floor being pierced with holes 3 of a second predetermined shape according to said first shape, to let through said orifices said cassons but not said particles, a ceiling 7 arranged substantially parallel to said floor; the device further comprising a second means 8 arranged to be able to move said ceiling between a first position in which it is at a distance d from the predetermined floor as a function of the smallest of the three dimensions of said particles (see Fig.
  • each particle is required to move in the device on its floor so that its axes of symmetry in each of its other dimensions are arranged parallel to the floor in question. This has the effect of preventing a particle from tipping into one of the orifices of said floor about an axis of symmetry orthogonal to the largest dimension of this particle.
  • the efficiency of separation by the device of particles of their cassons is advantageously improved.
  • the distance d is chosen so that the particles are lying on the floor 1, with their maximum extension parallel to the floor 1.
  • the size of the orifices 3 is chosen so that any particle having such a maximum extension parallel to the orifices 3 can not pass through these orifices.
  • the particles can not rock in the orifices as the tilting movement is blocked by the ceiling 7.
  • the second means 8 comprises a jack 4 connected to said ceiling and a motor 5 arranged to move the jack between the first and second position of the ceiling.
  • the second means 8 comprises an electronic control unit which controls the motor 5. On command of this electronic unit, the motor 5 brings the ceiling 7 into contact with the floor 1.
  • the electronic control unit can control the motor 5 such a movement once per periodic cycle.
  • Such a periodic cycle may have a period preferably between one minute and one hour, more preferably between two minutes and thirty minutes, even more preferably between five minutes and fifteen minutes.
  • the control of the motor 5 can be automated thanks to the electronic control unit.
  • the periodic and automated movement of the ceiling 7 makes it possible to periodically and automatically eject the cassons blocked in the orifices 3. This makes the device according to the invention particularly interesting in an industrial process.
  • the motor 5 can be a servomotor.
  • the floor is preferably removably arranged in the device, i.e. it can be removed from the device.
  • a plurality of floors each having orifices of a different second predetermined size, adapted to a first different form of particles may alternatively be included in the device according to the first specific form of the particles to be separated from their cassons by this device; which gives it a great versatility of use.
  • the device as illustrated further comprises a tray 9 for harvesting particle cassons arranged under the floor of the device, this tank being itself provided with an opening 10 arranged in said tank to allow the evacuation of the cassons harvested therein. , of the device.
  • the particles mentioned may be pharmaceutical tablets or capsules.
  • the particles preferably have a cylindrical symmetry, with an axial extension greater than a radial extension.
  • the particles may have an axial and / or radial extension between 2.5 and 25 mm, preferably between 5 and 10 mm, more preferably between 7 and 8 mm.
  • the particles may have spherical symmetry.
  • the particles may have a radius of between 2.5 and 25 mm, preferably between 5 and 10 mm, more preferably between 7 and 8 mm.
  • the orifices are circular. Preferably, they have a diameter between 2.5 and 25 mm, more preferably between 5 and 10 mm, even more preferably between 7 and 8 mm.
  • the distance d ( figure 1 ) between the ceiling 7 and the floor 1 in the first position is preferably 1 mm greater than the radial extension of the particles if they have a cylindrical symmetry, and 1 mm greater than the radius of the particles if they have a spherical symmetry.
  • the distance d is preferably between 3.5 and 26 mm, more preferably between 6 and 11 mm, more preferably between 7 and 8 mm.
  • the device I is a device for separating particles of p particles of a first form of said particles, comprising a floor 1 arranged to receive said particles and said cassons, connected to a first means 2 arranged to animate said floor with a vibratory movement, said floor being pierced with orifices 3 of a second predetermined shape according to said first shape for passing through said orifices said cassons but not said particles, a ceiling 7 arranged substantially parallel to said floor; and comprising a second means 8 arranged to be able to move said a ceiling between a first position in which it is at a distance d from the predetermined floor as a function of the smallest of the three dimensions of said particles and a second position in which it is substantially in contact with the floor so that jammed particles of particles in said orifices are expelled.

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Combined Means For Separation Of Solids (AREA)
  • Disintegrating Or Milling (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Description

La présente invention concerne un dispositif de séparation de cassons de particules desdites particules et un procédé de mise en oeuvre de ce dispositif. De tels dispositifs sont utilisés dans diverses industries lorsqu'il s'agit de séparer des particules d'une première forme, de cassons de telles particules auxquels ces dernières sont mélangées, de tels cassons pouvant notamment résulter du bris desdites particules lors de leur processus de fabrication. En particulier, dans l'industrie pharmaceutique, ces particules sont constituées de comprimés ou de gélules et il est important que seuls les comprimés ou gélules entiers aboutissent à la chaine d'emballage de ces derniers dans des contenants regroupant un certain nombre de ces comprimés ou gélules en vue de leur mise sur le marché.The present invention relates to a device for separating particle cassons from said particles and a method of implementing this device. Such devices are used in various industries when it is a question of separating particles of a first form, of cassons of such particles to which they are mixed, such cassons being able in particular to result from the breaking of said particles during their process of manufacturing. In particular, in the pharmaceutical industry, these particles consist of tablets or capsules and it is important that only whole tablets or capsules result in the packaging chain of the latter in containers containing a certain number of these tablets or capsules. capsules to be placed on the market.

Un tel dispositif comprend généralement un plancher agencé pour recevoir des particules d'une forme spécifique et des cassons de telles particules, connecté à un premier moyen agencé pour animer ledit plancher d'un mouvement vibratoire de sorte que les particules et cassons en question se déplacent sur le plancher dans une direction déterminée par le type de mouvement vibratoire qui lui est imprimé, ledit plancher étant percé de d'orifices d'une forme prédéterminée en fonction de la forme des particules, pour laisser passer au travers desdits orifices les cassons de telles particules mais pas les particules elles-mêmes.Such a device generally comprises a floor arranged to receive particles of a specific shape and cassons of such particles, connected to a first means arranged to animate said floor of a vibratory movement so that the particles and cassons in question move on the floor in a direction determined by the type of vibratory movement that is printed to it, said floor being pierced with orifices of a predetermined shape depending on the shape of the particles, to let through the said orifices the cassons of such particles but not the particles themselves.

Par exemple, les deux dimensions (longueur, largeur) d'un tel orifice peuvent être légèrement supérieures à deux des trois dimensions (longueur, largeur, hauteur) d'une particule, mais inférieures à sa troisième dimension. Ainsi, un casson de particule dont la troisième dimension est réduite relativement à celle d'une particule entière pourra aisément tomber dans l'orifice en question alors qu'une particule entière ne le pourrait que par basculement selon un axe de symétrie orthogonal à ladite troisième dimension. Dans un tel cas, la fraction de particules entières ayant néanmoins traversé le plancher du dispositif par certains de ses orifices peut être récupérée en amont par des moyens appropriés. Un tel dispositif comprend également généralement un plafond agencé sensiblement parallèlement au plancher du dispositif.For example, the two dimensions (length, width) of such an orifice may be slightly greater than two of the three dimensions (length, width, height) of a particle, but smaller than its third dimension. Thus, a particle casson whose third dimension is reduced relative to that of a whole particle can to fall easily into the hole in question whereas an entire particle could only fall by an axis of symmetry orthogonal to said third dimension. In such a case, the fraction of whole particles having nevertheless passed through the floor of the device by some of its orifices may be recovered upstream by appropriate means. Such a device also generally comprises a ceiling arranged substantially parallel to the floor of the device.

Le document FR2841161 , par exemple, décrit un tel dispositif, selon le préambule de la revendication 1, et, implicitement, un procédé selon le préambule de la revendication 12.The document FR2841161 for example, describes such a device, according to the preamble of claim 1, and, implicitly, a method according to the preamble of claim 12.

Un problème causé par de tels dispositifs est qu'il arrive que des cassons dont la troisième dimension est supérieure ou égale à l'une au moins des deux dimensions des orifices du plancher du dispositif se retrouvent coincés dans ces orifices et de la sorte les obstruent. Dans une telle situation, au fil du processus de séparation de cassons des particules entières par le dispositif, de plus en plus de orifices peuvent être obstrués de la sorte ce qui réduit d'autant l'efficacité de séparation de ce dispositif.A problem caused by such devices is that it happens that cassons whose third dimension is greater than or equal to at least one of the two dimensions of the openings of the floor of the device are stuck in these orifices and thus obstruct them . In such a situation, in the course of the process of separating cassons from whole particles by the device, more and more orifices may be obstructed in this way, which reduces the separation efficiency of this device accordingly.

Il est d'usage dans une telle situation d'interrompre le fonctionnement du dispositif pour manuellement ou grâce à des moyens mécaniques, désobstruer les orifices dans lesquels des cassons de particules sont restés coincés. Cette opération entraine dès lors des pertes de temps et donc de productivité et requiert également une main d'oeuvre additionnelle pour l'effectuer.It is customary in such a situation to interrupt the operation of the device for manual or mechanical means, unclog the orifices in which particles of particles have remained stuck. This operation therefore leads to loss of time and therefore productivity and also requires additional manpower to perform it.

L'invention résout le problème susmentionné en proposant un dispositif du type de celui décrit ci-dessus mais qui en outre comprend un second moyen agencé pour déplacer le plafond du dispositif entre une première position et une seconde position dans laquelle il est en contact avec le plancher de sorte que des cassons de particules coincés dans lesdits orifices en soient expulsés, selon la revendication 1.The invention solves the aforementioned problem by providing a device of the type described above but which further comprises second means arranged to move the ceiling of the device between a first position and a second position in which it is in contact with the device. floor so that particles of particles stuck in said orifices are expelled, according to claim 1.

Dans le document FR2841161 , le plafond, dénommé plaque, sert à contrôler la position des particules, mais reste à une distance fixe par rapport au plancher. Le dispositif décrit dans ce document ne permet donc pas de désobstruer les orifices.In the document FR2841161 , the ceiling, called plate, is used to control the position of particles, but remains at a fixed distance compared to the floor. The device described in this document does not allow to unclog the holes.

Préférentiellement, le premier moyen est un moyen de vibration. Préférentiellement, le premier moyen est connecté mécaniquement au plancher. Préférentiellement, le plancher et le plafond sont couplés mécaniquement. Préférentiellement, le second moyen est couplé mécaniquement au plafond.Preferably, the first means is a means of vibration. Preferably, the first means is mechanically connected to the floor. Preferably, the floor and the ceiling are mechanically coupled. Preferably, the second means is mechanically coupled to the ceiling.

L'invention concerne également un procédé de séparation de cassons de particules d'une première forme desdites particules, selon la revendication 12 et comprenant les étapes suivantes :

  • Grâce à un second moyen agencé à cet effet, disposer un plafond sensiblement parallèle à un plancher dans une première position dans laquelle il se trouve à une distance d'un plancher agencé pour recevoir des particules et des cassons de ces particules, ledit plancher étant percé de orifices;
  • Mettre en mouvement vibratoire le plancher grâce à un premier moyen agencé à cet effet ;
  • Introduire des particules et cassons de telles particules entre le plancher et le plafond ;
  • Interrompre ladite introduction à un instant prédéterminé ;
  • Interrompre le mouvement vibratoire du plancher une fois que plus aucun comprimé ou casson ne se trouve sur sa face faisant front au plafond ;
  • Déplacer grâce au second moyen, le plafond entre sa première position et une seconde position dans laquelle il est en contact avec le plancher de sorte que des cassons de particules coincés dans lesdits orifices en soient expulsés ;
  • Déplacer grâce au second moyen le plafond de sa seconde position à sa première position.
The invention also relates to a method for separating particle cassons of a first form of said particles, according to claim 12 and comprising the following steps:
  • With a second means arranged for this purpose, have a ceiling substantially parallel to a floor in a first position in which it is at a distance from a floor arranged to receive particles and cassons of these particles, said floor being pierced of orifices;
  • Vibratory movement of the floor through a first means arranged for this purpose;
  • Introduce particles and break up such particles between the floor and the ceiling;
  • Interrupting said introduction at a predetermined time;
  • Interrupt the vibratory movement of the floor once no more tablets or cassons are on the front of the ceiling;
  • Move through the second means, the ceiling between its first position and a second position in which it is in contact with the floor so that particles of particles stuck in said orifices are expelled;
  • Move through the second means the ceiling of its second position to its first position.

Ces étapes sont réalisées dans l'ordre indiqué ci-dessus.These steps are performed in the order indicated above.

Grâce au second moyen ci-dessus, il est possible périodiquement de forcer des cassons de particules qui seraient coincés dans des orifices du plancher du dispositif d'en être expulsés par pression sur ces cassons du plafond de ce dispositif lorsqu'il est amené dans sa seconde position sensiblement en contact avec la face du plancher faisant front au plafond en question. Ceci résout donc le problème évoqué plus haut puisque les orifices ainsi libérés redeviennent pleinement fonctionnels. Il suffit donc de déplacer le plafond du dispositif de sa première vers sa seconde position lorsque plus aucune particule ni casson se trouve encore en contact avec ladite face et que seuls des cassons se trouvent coincés dans des orifices du plancher du dispositif pour permettre à celui-ci de conserver sa qualité fonctionnelle au cours du temps, contrairement aux dispositifs selon l'état de la technique.Thanks to the second means above, it is possible periodically to force particles of particles that would be stuck in the openings of the floor of the device to be expelled by pressure on these cassons of the ceiling of this device when it is brought into its second position substantially in contact with the face of the floor facing the ceiling in question. This therefore solves the problem mentioned above since the orifices thus released become fully functional again. It is therefore sufficient to move the ceiling of the device from its first to its second position when no particle or casson is still in contact with said face and that only cassons are stuck in orifices of the floor of the device to allow it to it retains its functional quality over time, unlike devices according to the state of the art.

L'invention va à présent être décrite plus en détails en référence à un de ses modes de réalisation, non limitatif de la portée de cette invention, illustré par les figures jointes dans lesquelles :

  • La figure 1 est une vue en coupe verticale d'un dispositif selon l'invention dans la première position du plafond qu'il comprend ;
  • La figure 2 est une vue en coupe verticale du dispositif illustré par la figure 1 dans la seconde position du plafond qu'il comprend ;
  • La figure 3 est une vue en perspective du dispositif selon la figure 1.
The invention will now be described in more detail with reference to one of its embodiments, not limiting the scope of this invention, illustrated by the attached figures in which:
  • The figure 1 is a vertical sectional view of a device according to the invention in the first position of the ceiling that it comprises;
  • The figure 2 is a vertical sectional view of the device illustrated by the figure 1 in the second position of the ceiling that he understands;
  • The figure 3 is a perspective view of the device according to the figure 1 .

En se rapportant aux figures jointes, il y est représenté un dispositif I de séparation de cassons de particules p d'une première forme, desdites particules, comprenant un plancher 1 agencé pour recevoir lesdites particules et lesdits cassons, connecté à un premier moyen 2 agencé pour animer ledit plancher d'un mouvement vibratoire, ledit plancher étant percé de orifices 3 d'une seconde forme prédéterminée en fonction de ladite première forme, pour laisser passer au travers desdits orifices lesdits cassons mais pas lesdites particules, un plafond 7 agencé sensiblement parallèlement audit plancher; le dispositif comprenant en outre un second moyen 8 agencé pour pouvoir déplacer ledit plafond entre une première position dans laquelle il se trouve à une distance d du plancher prédéterminée en fonction de la plus petite des trois dimensions desdites particules (voir fig. 1) et une seconde position dans laquelle il est sensiblement en contact avec le plancher de sorte que des cassons de particules coincés dans lesdits orifices en soient expulsés (voir fig. 2). La distance d en question est choisie de sorte à être légèrement supérieure à ladite plus petite dimension des particules. De la sorte chaque particule est tenue de se déplacer dans le dispositif sur son plancher de telle sorte que ses axes de symétrie selon chacune de ses autres dimensions soient disposés parallèlement au plancher en question. Ceci a pour effet d'empêcher une particule de basculer dans un des orifices dudit plancher autour d'un axe de symétrie orthogonal à la plus grande dimension de cette particule. Ainsi, l'efficacité de séparation par le dispositif de particules de leurs cassons s'en trouve avantageusement améliorée.Referring to the attached figures, there is shown a device I for separating particle p particles of a first form, said particles comprising a floor 1 arranged to receive said particles and said cassons, connected to a first means 2 arranged to animate said floor with a vibratory movement, said floor being pierced with holes 3 of a second predetermined shape according to said first shape, to let through said orifices said cassons but not said particles, a ceiling 7 arranged substantially parallel to said floor; the device further comprising a second means 8 arranged to be able to move said ceiling between a first position in which it is at a distance d from the predetermined floor as a function of the smallest of the three dimensions of said particles (see Fig. 1 ) and a second position in which it is substantially in contact with the floor so that particles of particles stuck in said holes are expelled (see Fig. 2 ). The distance d in question is chosen to be slightly greater than said smaller dimension of the particles. In this way each particle is required to move in the device on its floor so that its axes of symmetry in each of its other dimensions are arranged parallel to the floor in question. This has the effect of preventing a particle from tipping into one of the orifices of said floor about an axis of symmetry orthogonal to the largest dimension of this particle. Thus, the efficiency of separation by the device of particles of their cassons is advantageously improved.

En d'autres termes, selon un mode de réalisation de l'invention, la distance d est choisie pour que les particules soient couchées sur le plancher 1, avec leur extension maximale parallèle au plancher 1. La taille des orifices 3 est choisie pour que toute particule présentant une telle extension maximale parallèlement aux orifices 3 ne puisse pas passer à travers ces orifices. En outre, les particules ne peuvent pas non plus basculer dans les orifices car le mouvement de basculement est bloqué par le plafond 7.In other words, according to one embodiment of the invention, the distance d is chosen so that the particles are lying on the floor 1, with their maximum extension parallel to the floor 1. The size of the orifices 3 is chosen so that any particle having such a maximum extension parallel to the orifices 3 can not pass through these orifices. In addition, the particles can not rock in the orifices as the tilting movement is blocked by the ceiling 7.

De préférence, tel qu'illustré par les figures, le second moyen 8 comprend un vérin 4 connecté audit plafond et à un moteur 5 agencé pour déplacer le vérin entre la première et la seconde position du plafond.Preferably, as shown in the figures, the second means 8 comprises a jack 4 connected to said ceiling and a motor 5 arranged to move the jack between the first and second position of the ceiling.

Dans un mode de réalisation de l'invention, le second moyen 8 comprend une unité électronique de commande qui contrôle le moteur 5. Sur commande de cette unité électronique, le moteur 5 amène le plafond 7 en contact avec le plancher 1. Par exemple, l'unité électronique de commande peut commander au moteur 5 un tel mouvement une fois par cycle périodique. Un tel cycle périodique peut avoir une période préférentiellement comprise entre une minute et une heure, plus préférentiellement entre deux minutes et trente minutes, encore plus préférentiellement entre cinq minutes et quinze minutes.In one embodiment of the invention, the second means 8 comprises an electronic control unit which controls the motor 5. On command of this electronic unit, the motor 5 brings the ceiling 7 into contact with the floor 1. For example, the electronic control unit can control the motor 5 such a movement once per periodic cycle. Such a periodic cycle may have a period preferably between one minute and one hour, more preferably between two minutes and thirty minutes, even more preferably between five minutes and fifteen minutes.

La commande du moteur 5 peut être automatisée grâce à l'unité électronique de commande. Le mouvement périodique et automatisé du plafond 7 permet d'éjecter périodiquement et automatiquement les cassons bloqués dans les orifices 3. Cela rend particulièrement intéressant le dispositif selon l'invention dans un processus industriel.The control of the motor 5 can be automated thanks to the electronic control unit. The periodic and automated movement of the ceiling 7 makes it possible to periodically and automatically eject the cassons blocked in the orifices 3. This makes the device according to the invention particularly interesting in an industrial process.

Le moteur 5 peut être un servomoteur.The motor 5 can be a servomotor.

Le plancher est de préférence agencé de manière amovible dans le dispositif, c'est-à-dire qu'il peut être enlevé du dispositif. Ainsi, une pluralité de planchers présentant chacun des orifices d'une seconde dimension prédéterminée différente, adaptée à une première forme différente de particules peuvent être alternativement compris dans le dispositif selon la première forme spécifique des particules à séparer de leurs cassons par ce dispositif, ce qui lui confère une grande polyvalence d'utilisation.The floor is preferably removably arranged in the device, i.e. it can be removed from the device. Thus, a plurality of floors each having orifices of a different second predetermined size, adapted to a first different form of particles may alternatively be included in the device according to the first specific form of the particles to be separated from their cassons by this device; which gives it a great versatility of use.

Le dispositif tel qu'illustré comprend encore un bac 9 de récolte des cassons de particules agencé sous le plancher du dispositif, ce bac étant pourvu lui-même d'une ouverture 10 agencée dans ledit bac pour permettre l'évacuation des cassons y étant récoltés, du dispositif.The device as illustrated further comprises a tray 9 for harvesting particle cassons arranged under the floor of the device, this tank being itself provided with an opening 10 arranged in said tank to allow the evacuation of the cassons harvested therein. , of the device.

Dans le cadre de la présente invention, les particules mentionnées peuvent être des comprimés ou gélules pharmaceutiques.In the context of the present invention, the particles mentioned may be pharmaceutical tablets or capsules.

Les particules ont, de préférence, une symétrie cylindrique, avec une extension axiale supérieure à une extension radiale. Les particules peuvent avoir une extension axiale et/ou radiale entre 2,5 et 25 mm, préférentiellement entre 5 et 10 mm, plus préférentiellement entre 7 et 8 mm.The particles preferably have a cylindrical symmetry, with an axial extension greater than a radial extension. The particles may have an axial and / or radial extension between 2.5 and 25 mm, preferably between 5 and 10 mm, more preferably between 7 and 8 mm.

Alternativement, les particules peuvent avoir une symétrie sphérique. Les particules peuvent avoir un rayon entre 2,5 et 25 mm, préférentiellement entre 5 et 10 mm, plus préférentiellement entre 7 et 8 mm.Alternatively, the particles may have spherical symmetry. The particles may have a radius of between 2.5 and 25 mm, preferably between 5 and 10 mm, more preferably between 7 and 8 mm.

Dans un mode de réalisation de l'invention, les orifices sont circulaires. Préférentiellement, ils ont un diamètre entre 2,5 et 25 mm, plus préférentiellement entre 5 et 10 mm, encore plus préférentiellement entre 7 et 8 mm.In one embodiment of the invention, the orifices are circular. Preferably, they have a diameter between 2.5 and 25 mm, more preferably between 5 and 10 mm, even more preferably between 7 and 8 mm.

La distance d (figure 1) entre le plafond 7 et le plancher 1 dans la première position est préférentiellement de 1 mm supérieure à l'extension radiale des particules si elles ont une symétrie cylindrique, et de 1 mm supérieure au rayon des particules si elles ont une symétrie sphérique. Par exemple, la distance d est préférentiellement comprise entre 3,5 et 26 mm, plus préférentiellement entre 6 et 11 mm, encore plus préférentiellement entre 7 et 8 mm.The distance d ( figure 1 ) between the ceiling 7 and the floor 1 in the first position is preferably 1 mm greater than the radial extension of the particles if they have a cylindrical symmetry, and 1 mm greater than the radius of the particles if they have a spherical symmetry. For example, the distance d is preferably between 3.5 and 26 mm, more preferably between 6 and 11 mm, more preferably between 7 and 8 mm.

Selon un mode de réalisation de l'invention, le dispositif I selon l'invention est un dispositif de séparation de cassons de particules p d'une première forme desdites particules, comprenant un plancher 1 agencé pour recevoir lesdites particules et lesdits cassons, connecté à un premier moyen 2 agencé pour animer ledit plancher d'un mouvement vibratoire, ledit plancher étant percé de orifices 3 d'une seconde forme prédéterminée en fonction de ladite première forme pour laisser passer au travers desdits orifices lesdits cassons mais pas lesdites particules, un plafond 7 agencé sensiblement parallèlement audit plancher; et comprenant un second moyen 8 agencé pour pouvoir déplacer ledit plafond entre une première position dans laquelle il se trouve à une distance d du plancher prédéterminée en fonction de la plus petite des trois dimensions desdites particules et une seconde position dans laquelle il est sensiblement en contact avec le plancher de sorte que des cassons de particules coincés dans lesdits orifices en soient expulsés.According to one embodiment of the invention, the device I according to the invention is a device for separating particles of p particles of a first form of said particles, comprising a floor 1 arranged to receive said particles and said cassons, connected to a first means 2 arranged to animate said floor with a vibratory movement, said floor being pierced with orifices 3 of a second predetermined shape according to said first shape for passing through said orifices said cassons but not said particles, a ceiling 7 arranged substantially parallel to said floor; and comprising a second means 8 arranged to be able to move said a ceiling between a first position in which it is at a distance d from the predetermined floor as a function of the smallest of the three dimensions of said particles and a second position in which it is substantially in contact with the floor so that jammed particles of particles in said orifices are expelled.

Selon un mode de réalisation de l'invention, le procédé selon l'invention est un procédé de séparation de cassons de particules (p) d'une première forme desdites particules, comprenant les étapes suivantes :

  • (i) Grâce à un second moyen 8 agencé à cet effet, disposer un plafond 7 sensiblement parallèle à un plancher 1 dans une première position dans laquelle il se trouve à une distance d d'un plancher agencé pour recevoir des particules et des cassons de ces particules, ledit plancher étant percé de orifices 3 d'une seconde forme prédéterminée en fonction de ladite première forme pour laisser passer au travers desdits orifices lesdits cassons mais pas lesdites particules, la distance d étant prédéterminée en fonction de la plus petite des trois dimensions desdites particules ;
  • (ii) Mettre en mouvement vibratoire le plancher grâce à un premier moyen 2 agencé à cet effet ;
  • (iii) Introduire des particules p et cassons de telles particules entre le plancher et le plafond ;
  • (iv) Interrompre ladite introduction à un instant prédéterminé ;
  • (v) Interrompre le mouvement vibratoire du plancher une fois que plus aucun comprimé ou casson ne se trouve sur sa face faisant front au plafond ;
  • (vi) Déplacer grâce au second moyen, le plafond entre sa première position et une seconde position dans laquelle il est sensiblement en contact avec le plancher de sorte que des cassons de particules coincés dans lesdits orifices en soient expulsés ;
  • (vi) Déplacer grâce au second moyen le plafond de sa seconde position à sa première position.
According to one embodiment of the invention, the method according to the invention is a process for separating particle cassons (p) from a first form of said particles, comprising the following steps:
  • (i) With a second means 8 arranged for this purpose, have a ceiling 7 substantially parallel to a floor 1 in a first position in which it is at a distance d from a floor arranged to receive particles and cassons of these particles, said floor being pierced with orifices 3 of a second predetermined shape according to said first shape to let through said orifices said cassons but not said particles, the distance d being predetermined according to the smallest of the three dimensions said particles;
  • (ii) vibrating the floor through a first means 2 arranged for this purpose;
  • (iii) Introduce p particles and break up such particles between the floor and the ceiling;
  • (iv) interrupting said introduction at a predetermined time;
  • (v) Interrupt the vibratory movement of the floor once there is no tablet or casson on its front facing the ceiling;
  • (vi) Move through the second means, the ceiling between its first position and a second position in which it is substantially in contact with the floor so that particles of particles stuck in said holes are expelled;
  • (vi) Move through the second means the ceiling from its second position to its first position.

Claims (15)

  1. Device (I) for separating particle (p) fragments from said particles (p) and comprising
    • a floor (1) bored with orifices (3) and arranged to receive said particles (p) and said fragments,
    • a first means (2) connected to said floor (1) and arranged to animate said floor (1) with a vibrating movement, and
    • a ceiling (7) arranged parallel to said floor (1),
    • a second means (8) arranged to move said ceiling (7) between a first position in which it is located at a non-nil distance (d) from the floor (1) and a second position;
    characterised in that said second position is a position in which said ceiling (7) is in contact with the floor (1).
  2. Device (I) according to claim 1, characterised in that said second means (8) comprises an actuator (4) connected to said ceiling (7) and to a motor (5) arranged to move the actuator (4) between the first and the second position of the ceiling (7).
  3. Device (I) according to claim 2, characterised in that the motor (5) is a servomotor.
  4. Device (I) according to claim 2 or 3, characterised in that said second means (8) further comprises an electronic control unit connected to the motor (5) and arranged to control said motor (5).
  5. Device (I) according to claim 4, characterised in that said electronic control unit is programmed to periodically bring the ceiling (7) into contact with the floor (1) using said motor (5).
  6. Device (I) according to any one of the preceding claims, characterised in that said floor (1) is arranged so that it can be removed in the device (I).
  7. Device (I) according to any one of the preceding claims, characterised in that it comprises a container (9) for collecting said fragments arranged under said floor (1).
  8. Device (I) according to claim 7, characterised in that an opening (10) is arranged in said container (9) to enable the release of fragments.
  9. Device (I) according to any one of the preceding claims, characterised in that the distance (d) is between 3.5 and 26mm, preferably between 6 and 11mm, more preferably between 8 and 9mm.
  10. Device (I) according to any one of the preceding claims, characterised in that the orifices (3) are circular and have a diameter of between 2.5 and 25mm, more preferably between 5 and 10mm, even more preferably between 7 and 8mm.
  11. System for separating particle (p) fragments from said particles (p) and comprising:
    • particles (p) of a first shape,
    • fragments of said particles, and
    • a device (l) according to any one of the preceding claims, where the orifices (3) have a second shape and where the distance (d) and the second shape of the orifices (3) are such that the orifices (3) are capable of letting said fragments pass, but not said particles (p).
  12. Method for separating particle (p) fragments from said particles (p), comprising the following steps and in the following order:
    (i) using a second means (8) arranged for this purpose, arranging a ceiling (7) parallel to a floor (1) in a first position wherein it is located at a distance (d) from said floor (1) arranged to receive particles (p) and fragments of these particles (p), said floor (1) being bored with orifices (3);
    (ii) vibrationally moving the floor (1) using a first means (2) arranged for this purpose;
    (iii) introducing particles (p) and fragments of such particles (p) between the floor (1) and the ceiling (7);
    (iv) interrupting said introduction at a predetermined moment;
    characterised in that it further comprises the following steps and in the following order:
    (v) interrupting the vibrating movement of the floor (1), when no more particles (p) or particle (p) fragments are located on one of the surfaces thereof opposing the ceiling (7);
    (vi) moving, using the second means (8), the ceiling (7) between the first position thereof and a second position in which it is in contact with the floor (1) such that particle (p) fragments trapped in the orifices (3) are expelled therefrom;
    (vii) moving, using the second means (8), the ceiling (7) from the second position thereof to the first position thereof.
  13. Method according to the preceding claim, characterised in that steps (iv) and (v) are temporally offset, such that the floor (1) continues to vibrate for a time interval after step (iv) to release from the floor (1), particles (p) and particle (p) fragments.
  14. Method according to any one of the two preceding claims, characterised in that steps (ii) to (vii) are repeated at least once following step (vii).
  15. Method according to the preceding claim, characterised in that steps (ii) to (vii) are periodically repeated following step (vii).
EP16767179.1A 2015-09-07 2016-09-07 Device and process for separating particle fragments from said particles Active EP3347142B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BE2015/0228A BE1024079B1 (en) 2015-09-07 2015-09-07 DEVICE FOR SEPARATING PARTICLE CASSONS FROM SAID PARTICLES
PCT/EP2016/071060 WO2017042202A1 (en) 2015-09-07 2016-09-07 Device for separating particle fragments from said particles

Publications (2)

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EP3347142A1 EP3347142A1 (en) 2018-07-18
EP3347142B1 true EP3347142B1 (en) 2019-06-19

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US (1) US10568812B2 (en)
EP (1) EP3347142B1 (en)
CN (1) CN107949440B (en)
BE (1) BE1024079B1 (en)
ES (1) ES2741536T3 (en)
WO (1) WO2017042202A1 (en)

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CN113171301A (en) * 2021-03-20 2021-07-27 重庆赛维药业有限公司 Automatic capsule filling device that pregabalin capsule preparation was used

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Also Published As

Publication number Publication date
ES2741536T3 (en) 2020-02-11
EP3347142A1 (en) 2018-07-18
BE1024079B1 (en) 2017-11-13
US20180311109A1 (en) 2018-11-01
BE1024079A1 (en) 2017-11-10
WO2017042202A1 (en) 2017-03-16
US10568812B2 (en) 2020-02-25
CN107949440B (en) 2021-12-24
CN107949440A (en) 2018-04-20

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