EP3325157A4 - Reconfigurable microfluidic systems: homogeneous assays - Google Patents

Reconfigurable microfluidic systems: homogeneous assays Download PDF

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Publication number
EP3325157A4
EP3325157A4 EP16830993.8A EP16830993A EP3325157A4 EP 3325157 A4 EP3325157 A4 EP 3325157A4 EP 16830993 A EP16830993 A EP 16830993A EP 3325157 A4 EP3325157 A4 EP 3325157A4
Authority
EP
European Patent Office
Prior art keywords
microfluidic systems
homogeneous assays
reconfigurable microfluidic
reconfigurable
assays
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP16830993.8A
Other languages
German (de)
French (fr)
Other versions
EP3325157A1 (en
Inventor
Hong Jiao
Erik C. Jensen
Homayun Mehrabani
Liran Yosef Haller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hj Science & Technology Inc
Original Assignee
Hj Science & Technology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US14/808,933 external-priority patent/US9956557B2/en
Priority claimed from US14/808,939 external-priority patent/US9733239B2/en
Priority claimed from US14/808,929 external-priority patent/US9956558B2/en
Application filed by Hj Science & Technology Inc filed Critical Hj Science & Technology Inc
Publication of EP3325157A1 publication Critical patent/EP3325157A1/en
Publication of EP3325157A4 publication Critical patent/EP3325157A4/en
Pending legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087—Multiple sequential chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B01L2300/165—Specific details about hydrophobic, oleophobic surfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/084—Passive control of flow resistance
    • B01L2400/088—Passive control of flow resistance by specific surface properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
EP16830993.8A 2015-07-24 2016-06-27 Reconfigurable microfluidic systems: homogeneous assays Pending EP3325157A4 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US14/808,933 US9956557B2 (en) 2015-07-24 2015-07-24 Reconfigurable microfluidic systems: microwell plate interface
US14/808,939 US9733239B2 (en) 2015-07-24 2015-07-24 Reconfigurable microfluidic systems: scalable, multiplexed immunoassays
US14/808,929 US9956558B2 (en) 2015-07-24 2015-07-24 Reconfigurable microfluidic systems: homogeneous assays
PCT/US2016/039619 WO2017019221A1 (en) 2015-07-24 2016-06-27 Reconfigurable microfluidic systems: homogeneous assays

Publications (2)

Publication Number Publication Date
EP3325157A1 EP3325157A1 (en) 2018-05-30
EP3325157A4 true EP3325157A4 (en) 2018-12-12

Family

ID=57885008

Family Applications (2)

Application Number Title Priority Date Filing Date
EP16830993.8A Pending EP3325157A4 (en) 2015-07-24 2016-06-27 Reconfigurable microfluidic systems: homogeneous assays
EP16830997.9A Pending EP3325158A4 (en) 2015-07-24 2016-06-29 Reconfigurable microfluidic systems: scalable, multiplexed immunoassays

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP16830997.9A Pending EP3325158A4 (en) 2015-07-24 2016-06-29 Reconfigurable microfluidic systems: scalable, multiplexed immunoassays

Country Status (4)

Country Link
EP (2) EP3325157A4 (en)
CN (2) CN108290154B (en)
CA (2) CA2992447C (en)
WO (2) WO2017019221A1 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120329142A1 (en) * 2006-03-15 2012-12-27 Micronics, Inc. Integrated nucleic acid assays
US20130130262A1 (en) * 2010-01-29 2013-05-23 C. Frederick Battrell Sample-to-answer microfluidic cartridge

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001249071B2 (en) * 2000-02-23 2005-09-08 Caliper Life Sciences, Inc. Multi-reservoir pressure control system
US7605002B2 (en) * 2002-09-06 2009-10-20 Epigem Limited Modular microfluidic system
US7011793B2 (en) * 2003-05-15 2006-03-14 Kionix, Inc. Reconfigurable modular microfluidic system and method of fabrication
US7976795B2 (en) * 2006-01-19 2011-07-12 Rheonix, Inc. Microfluidic systems
WO2008103824A1 (en) * 2007-02-23 2008-08-28 Chinese Academy Of Inspection And Quarantine (Caiq) Sensitivity-enhanced dot-antibody linked immunogold assay for virus detection
PL2504105T3 (en) * 2009-11-24 2021-06-28 Opko Diagnostics, Llc Fluid mixing and delivery in microfluidic systems
CA2882675C (en) * 2011-10-09 2020-02-25 Bonnie L. GRAY Microfluidic reconfigurable device for multi-plexed sample analysis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120329142A1 (en) * 2006-03-15 2012-12-27 Micronics, Inc. Integrated nucleic acid assays
US20130130262A1 (en) * 2010-01-29 2013-05-23 C. Frederick Battrell Sample-to-answer microfluidic cartridge

Also Published As

Publication number Publication date
CN108290154B (en) 2021-07-30
WO2017019221A1 (en) 2017-02-02
CN108290153A (en) 2018-07-17
CN108290154A (en) 2018-07-17
CA2992434A1 (en) 2017-02-02
WO2017019241A1 (en) 2017-02-02
CA2992434C (en) 2023-08-08
CA2992447A1 (en) 2017-02-02
EP3325158A4 (en) 2018-12-12
CA2992447C (en) 2023-08-29
EP3325158A1 (en) 2018-05-30
EP3325157A1 (en) 2018-05-30

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