EP3314022A4 - Egfr assay - Google Patents

Egfr assay Download PDF

Info

Publication number
EP3314022A4
EP3314022A4 EP16815314.6A EP16815314A EP3314022A4 EP 3314022 A4 EP3314022 A4 EP 3314022A4 EP 16815314 A EP16815314 A EP 16815314A EP 3314022 A4 EP3314022 A4 EP 3314022A4
Authority
EP
European Patent Office
Prior art keywords
egfr assay
egfr
assay
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP16815314.6A
Other languages
German (de)
French (fr)
Other versions
EP3314022A1 (en
Inventor
Jeffrey D. WUITSCHICK
Kevin S. NELSON
Shihai Huang
Rupinder KULAR
Carolyn Mullen
James Rhoads
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Molecular Inc
Original Assignee
Abbott Molecular Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Molecular Inc filed Critical Abbott Molecular Inc
Publication of EP3314022A1 publication Critical patent/EP3314022A1/en
Publication of EP3314022A4 publication Critical patent/EP3314022A4/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP16815314.6A 2015-06-23 2016-06-23 Egfr assay Pending EP3314022A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562183566P 2015-06-23 2015-06-23
PCT/US2016/039041 WO2016210147A1 (en) 2015-06-23 2016-06-23 Egfr assay

Publications (2)

Publication Number Publication Date
EP3314022A1 EP3314022A1 (en) 2018-05-02
EP3314022A4 true EP3314022A4 (en) 2019-05-01

Family

ID=57586424

Family Applications (1)

Application Number Title Priority Date Filing Date
EP16815314.6A Pending EP3314022A4 (en) 2015-06-23 2016-06-23 Egfr assay

Country Status (5)

Country Link
US (2) US10538815B2 (en)
EP (1) EP3314022A4 (en)
CA (1) CA2990441A1 (en)
HK (1) HK1254915A1 (en)
WO (1) WO2016210147A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10538815B2 (en) 2015-06-23 2020-01-21 Abbott Molecular Inc. EGFR assay
WO2021041762A1 (en) * 2019-08-28 2021-03-04 An Hsu Kit and methods to detect egfr variant iii
CN110863053A (en) * 2019-12-18 2020-03-06 广州迈景基因医学科技有限公司 Primer, probe and method for detecting EGFR vIII mutant

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6127126A (en) * 1989-09-08 2000-10-03 The Johns Hopkins University Method for diagnosing glioma associated with structural alterations of the EGF receptor gene in human tumors
WO2008033495A2 (en) * 2006-09-15 2008-03-20 Life Science Pharmaceuticals Method for detecting and treating skin disorders
WO2008109373A1 (en) * 2007-03-02 2008-09-12 Mdrna, Inc. Nucleic acid compounds for inhibiting erbb gene expression and uses thereof
WO2008119565A2 (en) * 2007-04-03 2008-10-09 Micromet Ag Cross-species-specific binding domain
WO2010028054A1 (en) * 2008-09-02 2010-03-11 Alnylam Europe Ag. Compositions and methods for inhibiting expression of mutant egfr gene
WO2011035465A1 (en) * 2009-09-22 2011-03-31 上海市肿瘤研究所 Specific binding proteins and uses thereof
US20140161894A1 (en) * 2006-05-26 2014-06-12 Alnylam Pharmaceuticals, Inc. Sirna silencing of genes expressed in cancer

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5242794A (en) 1984-12-13 1993-09-07 Applied Biosystems, Inc. Detection of specific sequences in nucleic acids
US4988617A (en) 1988-03-25 1991-01-29 California Institute Of Technology Method of detecting a nucleotide change in nucleic acids
US5494810A (en) 1990-05-03 1996-02-27 Cornell Research Foundation, Inc. Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease
JP4527338B2 (en) 1999-11-16 2010-08-18 キアゲン ゲゼルシャフト ミット ベシュレンクテル ハフツング Dye-labeled oligonucleotides for labeling nucleic acid molecules
US6582938B1 (en) 2001-05-11 2003-06-24 Affymetrix, Inc. Amplification of nucleic acids
DE10259374A1 (en) 2002-12-18 2004-07-08 Atto-Tec Gmbh Carboxamide-substituted dyes for analytical applications
DE10329860A1 (en) 2003-07-02 2005-01-20 Atto-Tec Gmbh Sulfonamide derivatives of polycyclic dyes for analytical applications
EP2163563A1 (en) 2006-03-31 2010-03-17 Massachusetts Institute of Technology Treatment of tumors expressing mutant EGF receptors
EP1978103A1 (en) 2007-04-03 2008-10-08 Bergen Teknologioverforing AS Method and kits for detection of EGFRvIII
WO2009030239A1 (en) 2007-09-06 2009-03-12 Genmab A/S Novel methods and antibodies for treating cancer
US10174361B2 (en) * 2011-11-10 2019-01-08 Exosome Diagnostics, Inc. Cerebrospinal fluid assay
JP6673698B2 (en) * 2013-02-15 2020-03-25 エクソサム ダイアグノスティクス，インコーポレイティド Novel EGFR variants
US10538815B2 (en) 2015-06-23 2020-01-21 Abbott Molecular Inc. EGFR assay

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6127126A (en) * 1989-09-08 2000-10-03 The Johns Hopkins University Method for diagnosing glioma associated with structural alterations of the EGF receptor gene in human tumors
US20140161894A1 (en) * 2006-05-26 2014-06-12 Alnylam Pharmaceuticals, Inc. Sirna silencing of genes expressed in cancer
WO2008033495A2 (en) * 2006-09-15 2008-03-20 Life Science Pharmaceuticals Method for detecting and treating skin disorders
WO2008109373A1 (en) * 2007-03-02 2008-09-12 Mdrna, Inc. Nucleic acid compounds for inhibiting erbb gene expression and uses thereof
WO2008119565A2 (en) * 2007-04-03 2008-10-09 Micromet Ag Cross-species-specific binding domain
WO2010028054A1 (en) * 2008-09-02 2010-03-11 Alnylam Europe Ag. Compositions and methods for inhibiting expression of mutant egfr gene
WO2011035465A1 (en) * 2009-09-22 2011-03-31 上海市肿瘤研究所 Specific binding proteins and uses thereof

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 21 April 2010 (2010-04-21), "Sequence 15 from Patent WO2010028054.", retrieved from EBI accession no. EM_PAT:HC480058 Database accession no. HC480058 *
DATABASE Geneseq [online] 11 December 2008 (2008-12-11), "Cynomolgus Epidermal growth factor receptor forward PCR primer # 1.", retrieved from EBI accession no. GSN:ATS31349 Database accession no. ATS31349 *
DATABASE Geneseq [online] 13 November 2008 (2008-11-13), "Human ERBB mRNA target sequence for mdRNA, SEQ ID:1346.", retrieved from EBI accession no. GSN:ATM28002 Database accession no. ATM28002 *
DATABASE Geneseq [online] 19 February 2001 (2001-02-19), "Nucleotide fragment of a mutant type II EGFR polypeptide.", retrieved from EBI accession no. GSN:AAC61541 Database accession no. AAC61541 *
DATABASE Geneseq [online] 31 July 2014 (2014-07-31), "Human/mouse EGFR gene-targeted siRNA, SEQ ID 8306.", retrieved from EBI accession no. GSN:BBH29120 Database accession no. BBH29120 *
MIN ZHOU ET AL: "EGFRvIII mRNA detection in the serum of patients with hepatocellular carcinoma : Letters to the Editor", LIVER INTERNATIONAL, vol. 30, no. 6, 1 July 2010 (2010-07-01), GB, pages 925 - 927, XP055531771, ISSN: 1478-3223, DOI: 10.1111/j.1478-3231.2010.02233.x *
S. WHEELER ET AL: "Tumor Epidermal Growth Factor Receptor and EGFR PY1068 Are Independent Prognostic Indicators for Head and Neck Squamous Cell Carcinoma", CLINICAL CANCER RESEARCH, vol. 18, no. 8, 20 February 2012 (2012-02-20), US, pages 2278 - 2289, XP055531743, ISSN: 1078-0432, DOI: 10.1158/1078-0432.CCR-11-1593 *
See also references of WO2016210147A1 *

Also Published As

Publication number Publication date
HK1254915A1 (en) 2019-08-02
EP3314022A1 (en) 2018-05-02
US20200172983A1 (en) 2020-06-04
CA2990441A1 (en) 2016-12-29
WO2016210147A1 (en) 2016-12-29
US20160376665A1 (en) 2016-12-29
US11279982B2 (en) 2022-03-22
US10538815B2 (en) 2020-01-21

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