EP3310342A4 - Inorganic controlled release particles with fast drug loading - Google Patents

Inorganic controlled release particles with fast drug loading Download PDF

Info

Publication number
EP3310342A4
EP3310342A4 EP16812105.1A EP16812105A EP3310342A4 EP 3310342 A4 EP3310342 A4 EP 3310342A4 EP 16812105 A EP16812105 A EP 16812105A EP 3310342 A4 EP3310342 A4 EP 3310342A4
Authority
EP
European Patent Office
Prior art keywords
controlled release
drug loading
release particles
fast drug
inorganic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP16812105.1A
Other languages
German (de)
French (fr)
Other versions
EP3310342A1 (en
Inventor
Sanjib Bhattacharyya
Paul Ducheyne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Pennsylvania Penn
Original Assignee
University of Pennsylvania Penn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Pennsylvania Penn filed Critical University of Pennsylvania Penn
Publication of EP3310342A1 publication Critical patent/EP3310342A1/en
Publication of EP3310342A4 publication Critical patent/EP3310342A4/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5115—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
    • A61K47/6923—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being an inorganic particle, e.g. ceramic particles, silica particles, ferrite or synsorb
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Ceramic Engineering (AREA)
  • Optics & Photonics (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
EP16812105.1A 2015-06-16 2016-05-13 Inorganic controlled release particles with fast drug loading Pending EP3310342A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562180345P 2015-06-16 2015-06-16
PCT/US2016/032408 WO2016204896A1 (en) 2015-06-16 2016-05-13 Inorganic controlled release particles with fast drug loading

Publications (2)

Publication Number Publication Date
EP3310342A1 EP3310342A1 (en) 2018-04-25
EP3310342A4 true EP3310342A4 (en) 2019-03-06

Family

ID=57545871

Family Applications (1)

Application Number Title Priority Date Filing Date
EP16812105.1A Pending EP3310342A4 (en) 2015-06-16 2016-05-13 Inorganic controlled release particles with fast drug loading

Country Status (3)

Country Link
EP (1) EP3310342A4 (en)
CA (1) CA2989795C (en)
WO (1) WO2016204896A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT202000023665A1 (en) * 2020-10-07 2022-04-07 Brenta S R L NANOPARTICLES SYSTEM FOR VEHICLE AND ADMINISTRATION OF ACTIVE INGREDIENTS AND RELATED PRODUCTION METHOD, AS WELL AS BIOFILM ERADICATION ACTIVITIES

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040076681A1 (en) * 2002-10-21 2004-04-22 Dennis Donn M. Nanoparticle delivery system
EP1741717A1 (en) * 2005-07-05 2007-01-10 Interuniversitair Microelektronica Centrum Metal nanostructures and pharmaceutical compositions
WO2012149268A1 (en) * 2011-04-29 2012-11-01 Selecta Biociences, Inc. Tolerogenic synthetic nanocarriers for allergy therapy
EP2259798B1 (en) * 2008-03-05 2013-12-11 Baxter International Inc. Surface-modified particles and methods for targeted drug delivery

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005016873A1 (en) * 2005-04-12 2006-10-19 Magforce Nanotechnologies Ag New nano-particle useful for production of composition to treatment and/or prophylaxis of proliferative illnesses, cancer and bacterial infections, where nano-particle is bonded therapeutic substance
FR2921661B1 (en) * 2007-10-01 2013-05-31 Centre Nat Rech Scient INORGANIC ORGANIC HYBRID SOLID WITH MODIFIED SURFACE.
US8790621B2 (en) * 2010-04-12 2014-07-29 Iowa State University Research Foundation, Inc. Nanoparticles and nanoparticle compositions
EP2696855B1 (en) * 2011-04-13 2021-06-02 The Trustees Of The University Of Pennsylvania Coated mesoporous nanoparticles
US9567265B2 (en) * 2012-11-30 2017-02-14 Iowa State University Research Foundation, Inc. Catalysts and methods of using the same

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040076681A1 (en) * 2002-10-21 2004-04-22 Dennis Donn M. Nanoparticle delivery system
EP1741717A1 (en) * 2005-07-05 2007-01-10 Interuniversitair Microelektronica Centrum Metal nanostructures and pharmaceutical compositions
EP2259798B1 (en) * 2008-03-05 2013-12-11 Baxter International Inc. Surface-modified particles and methods for targeted drug delivery
WO2012149268A1 (en) * 2011-04-29 2012-11-01 Selecta Biociences, Inc. Tolerogenic synthetic nanocarriers for allergy therapy

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BR]NING C ET AL: "Aldehyde-functionalized ethoxysilanes as new enzyme immobilization reagents", JOURNAL OF THE CHEMICAL SOCIETY, CHEMICAL COMMUNICATIONS, 1995, pages 2323 - 2324, XP002965494, ISSN: 0022-4936, DOI: 10.1039/C39950002323 *
GAO ZHENYUAN ET AL: "Aldehydepropyl-functionalized mesostructured cellular foams: Efficient supports for immobilization of penicillin G acylase", JOURNAL OF MOLECULAR CATALYSIS. B, ENZYMATIC, vol. 105, 21 April 2014 (2014-04-21), pages 111 - 117, XP029026137, ISSN: 1381-1177, DOI: 10.1016/J.MOLCATB.2014.04.006 *
LATTERICH MARTIN ET AL: "Label-free detection of biomolecular interactions in real time with a nano-porous silicon-based detection method", PROTEOME SCIENCE, vol. 6, no. 1, 4 November 2008 (2008-11-04), pages 31, XP021043843, ISSN: 1477-5956, DOI: 10.1186/1477-5956-6-31 *
See also references of WO2016204896A1 *
XUANJUN WU ET AL: "Cytosolic delivery of proteins mediated by aldehyde-displaying silica nanoparticles with pH-responsive characteristics", JOURNAL OF MATERIALS CHEMISTRY, vol. 22, no. 33, 2012, pages 17121, XP055543145, ISSN: 0959-9428, DOI: 10.1039/c2jm33434h *
YANG LING ET AL: "One-pot synthesis of aldehyde-functionalized mesoporous silica-Fe3O4nanocomposites for immobilization of penicillin G acylase", MICROPOROUS AND MESOPOROUS MATERIALS, vol. 197, 5 June 2014 (2014-06-05), pages 1 - 7, XP029015821, ISSN: 1387-1811, DOI: 10.1016/J.MICROMESO.2014.05.044 *

Also Published As

Publication number Publication date
WO2016204896A1 (en) 2016-12-22
CA2989795C (en) 2023-12-12
CA2989795A1 (en) 2016-12-22
EP3310342A1 (en) 2018-04-25

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