EP3308167A4 - Use of fluorescence for the quick and easy determination of s-adenosylmethionine, s-adenosylhomocysteine and homocysteine - Google Patents
Use of fluorescence for the quick and easy determination of s-adenosylmethionine, s-adenosylhomocysteine and homocysteine Download PDFInfo
- Publication number
- EP3308167A4 EP3308167A4 EP16800682.3A EP16800682A EP3308167A4 EP 3308167 A4 EP3308167 A4 EP 3308167A4 EP 16800682 A EP16800682 A EP 16800682A EP 3308167 A4 EP3308167 A4 EP 3308167A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- adenosylhomocysteine
- adenosylmethionine
- homocysteine
- fluorescence
- quick
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- FFFHZYDWPBMWHY-VKHMYHEASA-N L-homocysteine Chemical compound OC(=O)[C@@H](N)CCS FFFHZYDWPBMWHY-VKHMYHEASA-N 0.000 title 1
- ZJUKTBDSGOFHSH-WFMPWKQPSA-N S-Adenosylhomocysteine Chemical compound O[C@@H]1[C@H](O)[C@@H](CSCC[C@H](N)C(O)=O)O[C@H]1N1C2=NC=NC(N)=C2N=C1 ZJUKTBDSGOFHSH-WFMPWKQPSA-N 0.000 title 1
- MEFKEPWMEQBLKI-AIRLBKTGSA-N S-adenosyl-L-methioninate Chemical compound O[C@@H]1[C@H](O)[C@@H](C[S+](CC[C@H](N)C([O-])=O)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 MEFKEPWMEQBLKI-AIRLBKTGSA-N 0.000 title 1
- 229960001570 ademetionine Drugs 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/60—Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4737—C-reactive protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562166044P | 2015-05-25 | 2015-05-25 | |
PCT/US2016/034202 WO2016191507A1 (en) | 2015-05-25 | 2016-05-25 | Use of fluorescence for the quick and easy determination of s-adenosylmethionine, s-adenosylhomocysteine and homocysteine |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3308167A1 EP3308167A1 (en) | 2018-04-18 |
EP3308167A4 true EP3308167A4 (en) | 2019-02-13 |
Family
ID=61597837
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP16800682.3A Ceased EP3308167A4 (en) | 2015-05-25 | 2016-05-25 | Use of fluorescence for the quick and easy determination of s-adenosylmethionine, s-adenosylhomocysteine and homocysteine |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP3308167A4 (en) |
CN (1) | CN108291908A (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109444298B (en) * | 2018-08-28 | 2021-07-27 | 北京顺鑫农业股份有限公司牛栏山酒厂 | Method for rapidly excavating and measuring adenosylmethionine in white spirit brewing process |
CN109270274A (en) * | 2018-11-08 | 2019-01-25 | 重庆新赛亚生物科技有限公司 | It is a kind of can in quantitative detection peripheral blood c reactive protein content test strips and preparation method |
CN115754283B (en) * | 2022-12-06 | 2024-02-27 | 珠海市慧康生物科技有限公司 | Immune test strip based on quantum dot chemical luminescence method and preparation method thereof |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090263879A1 (en) * | 2008-04-21 | 2009-10-22 | Chiu Chin Chang | Immunoassay for specific determination of S-adenosylmethionine and analogs thereof in biological samples |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6379622B1 (en) * | 2001-04-11 | 2002-04-30 | Motorola, Inc. | Sensor incorporating a quantum dot as a reference |
US8476034B2 (en) * | 2003-07-10 | 2013-07-02 | General Atomics | Methods and compositions for assaying homocysteine |
CN1773283A (en) * | 2005-11-11 | 2006-05-17 | 袁洪 | Integrated testing method for protein marker rolated to predicting cardiocerebrovascular diseases accuring |
CN101246177A (en) * | 2007-02-14 | 2008-08-20 | 北京华安佛医药研究中心有限公司 | Homo-type cysteine immunity colloidal gold detecting test paper and method for producing the same |
CN202149903U (en) * | 2011-05-19 | 2012-02-22 | 博阳生物科技(上海)有限公司 | Time-resolved fluorescence immune chromatography quantitative detection test strip for C-reactive protein |
CN103172941A (en) * | 2011-12-26 | 2013-06-26 | 苏州新波生物技术有限公司 | Polystyrene fluorescent nanometer particle as well as preparation method and applications thereof |
CN102539785B (en) * | 2011-12-29 | 2014-12-24 | 深圳康美生物科技股份有限公司 | Fluorescent immunochromatography method for whole quantitative detection of C-reactive protein and reagent kit thereof |
CN102967713A (en) * | 2012-11-29 | 2013-03-13 | 深圳市伯劳特生物制品有限公司 | Homocysteine detection kit and preparation method thereof |
CN105492012B (en) * | 2013-03-15 | 2018-03-13 | 湖南天合生物技术有限公司 | Immunologic detection method based on SAM analog and applied to instructing personalized medicine |
JP2015133359A (en) * | 2014-01-09 | 2015-07-23 | 株式会社村田製作所 | Negative characteristic thermistor and method of manufacturing the same |
-
2016
- 2016-05-25 CN CN201680032653.5A patent/CN108291908A/en active Pending
- 2016-05-25 EP EP16800682.3A patent/EP3308167A4/en not_active Ceased
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090263879A1 (en) * | 2008-04-21 | 2009-10-22 | Chiu Chin Chang | Immunoassay for specific determination of S-adenosylmethionine and analogs thereof in biological samples |
Non-Patent Citations (3)
Title |
---|
GASPARYAN V K: "Synthesis of Water-Soluble CdSe Quantum Dots With Various Fluorescent Properties and Their Application in Immunoassay for Determination of C-Reactive Protein", JOURNAL OF FLUORESCENCE, PLENUM PUBLISHING, NEW YORK, US, vol. 24, no. 5, 18 July 2014 (2014-07-18), pages 1433 - 1438, XP035388195, ISSN: 1053-0509, [retrieved on 20140718], DOI: 10.1007/S10895-014-1426-8 * |
See also references of WO2016191507A1 * |
TARKKINEN P ET AL: "ULTRARAPID, ULTRASENSITIVE ONE-STEP KINETIC IMMUNOASSAY FOR C-REACTIVE PROTEIN (CRP) IN WHOLE BLOOD SAMPLES: MEASUREMENT OF THE ENTIRE CRP CONCENTRATION RANGE WITH A SINGLE SAMPLE DILUTION", CLINICAL CHEMISTRY, AMERICAN ASSOCIATION FOR CLINICAL CHEMISTRY, WASHINGTON, DC, vol. 48, no. 2, 1 February 2002 (2002-02-01), pages 269 - 277, XP001115951, ISSN: 0009-9147 * |
Also Published As
Publication number | Publication date |
---|---|
CN108291908A (en) | 2018-07-17 |
EP3308167A1 (en) | 2018-04-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL264565A (en) | Adenosine nucleobase editors and uses thereof | |
HRP20181742T1 (en) | Hydroxyalkyl-substituted phenyltriazole derivatives and uses thereof | |
IL258821A (en) | Nucleobase editors and uses thereof | |
IL289099A (en) | Methods for the storage of whole blood, and compositions thereof | |
HK1243999A1 (en) | Novel 3-indol substituted derivatives, pharmaceutical compositions and methods for use | |
EP3337481A4 (en) | Human tlr8-selective agonists | |
EP3262022A4 (en) | Phenylethynylnaphthalene dyes and methods for their use | |
EP3233879A4 (en) | Substituted nucleosides, nucleotides and analogs thereof | |
EP3160476A4 (en) | Substituted nucleosides, nucleotides and analogs thereof | |
EP3160475A4 (en) | Substituted nucleosides, nucleotides and analogs thereof | |
EP3253773A4 (en) | Substituted nucleosides, nucleotides and analogs thereof | |
PL3380086T3 (en) | Cyp26-resistant rar-alpha selective agonists in the treatment of cancer | |
EP3394230A4 (en) | Metalworking fluid | |
HK1243041A1 (en) | Barrel for co2-containing drinks and use thereof | |
EP3383401A4 (en) | Thieno-pyrimidine derivatives and uses thereof | |
EP3299371A4 (en) | Hydroxyl purine compounds and use thereof | |
EP3308167A4 (en) | Use of fluorescence for the quick and easy determination of s-adenosylmethionine, s-adenosylhomocysteine and homocysteine | |
IL255039B (en) | Reamer | |
EP3556764A4 (en) | Nucleoside derivative and use therefor | |
PL3386988T3 (en) | Novel dihydropyranopyrimidinone derivatives, and use thereof | |
EP3397627A4 (en) | Indolizine derivatives, composition and methods of use | |
HUE048394T2 (en) | Novel triazolopyrimidinone or triazolopyridinone derivatives, and use thereof | |
IL259900A (en) | Aminoazole derivatives, compositions containing same and uses thereof | |
GB201808388D0 (en) | Nucleobase editors and uses thereof | |
EP3166946A4 (en) | Novel imidazotriazinone or imidazopyrazinone derivatives, and use thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
17P | Request for examination filed |
Effective date: 20171219 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
AX | Request for extension of the european patent |
Extension state: BA ME |
|
DAV | Request for validation of the european patent (deleted) | ||
DAX | Request for extension of the european patent (deleted) | ||
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C07K 16/00 20060101ALI20180919BHEP Ipc: G01N 33/533 20060101AFI20180919BHEP Ipc: C12Q 1/48 20060101ALI20180919BHEP Ipc: G01N 33/573 20060101ALI20180919BHEP Ipc: G01N 33/543 20060101ALI20180919BHEP |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20190115 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: G01N 33/543 20060101ALI20190109BHEP Ipc: G01N 33/533 20060101AFI20190109BHEP Ipc: G01N 33/573 20060101ALI20190109BHEP Ipc: C12Q 1/48 20060101ALI20190109BHEP Ipc: C07K 16/00 20060101ALI20190109BHEP |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |
|
17Q | First examination report despatched |
Effective date: 20200930 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R003 |
|
APBK | Appeal reference recorded |
Free format text: ORIGINAL CODE: EPIDOSNREFNE |
|
APBN | Date of receipt of notice of appeal recorded |
Free format text: ORIGINAL CODE: EPIDOSNNOA2E |
|
APBR | Date of receipt of statement of grounds of appeal recorded |
Free format text: ORIGINAL CODE: EPIDOSNNOA3E |
|
APAF | Appeal reference modified |
Free format text: ORIGINAL CODE: EPIDOSCREFNE |
|
APBT | Appeal procedure closed |
Free format text: ORIGINAL CODE: EPIDOSNNOA9E |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED |
|
18R | Application refused |
Effective date: 20230325 |