EP3283649A4 - Method and system for microbiome-derived characterization, diagnostics, and therapeutics for cardiovascular disease conditions - Google Patents

Method and system for microbiome-derived characterization, diagnostics, and therapeutics for cardiovascular disease conditions Download PDF

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Publication number
EP3283649A4
EP3283649A4 EP16780655.3A EP16780655A EP3283649A4 EP 3283649 A4 EP3283649 A4 EP 3283649A4 EP 16780655 A EP16780655 A EP 16780655A EP 3283649 A4 EP3283649 A4 EP 3283649A4
Authority
EP
European Patent Office
Prior art keywords
microbiome
therapeutics
diagnostics
cardiovascular disease
disease conditions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP16780655.3A
Other languages
German (de)
French (fr)
Other versions
EP3283649A1 (en
Inventor
Zachary APTE
Daniel Almonacid
Jessica RICHMAN
Siavosh Rezvan BEHBAHANI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Psomagen Inc
Original Assignee
uBiome Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by uBiome Inc filed Critical uBiome Inc
Publication of EP3283649A1 publication Critical patent/EP3283649A1/en
Publication of EP3283649A4 publication Critical patent/EP3283649A4/en
Pending legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20—Supervised data analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/70—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
EP16780655.3A 2015-04-14 2016-04-13 Method and system for microbiome-derived characterization, diagnostics, and therapeutics for cardiovascular disease conditions Pending EP3283649A4 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201562147364P 2015-04-14 2015-04-14
US201562147092P 2015-04-14 2015-04-14
US201562147337P 2015-04-14 2015-04-14
US201562147304P 2015-04-14 2015-04-14
US201562147217P 2015-04-14 2015-04-14
PCT/US2016/027341 WO2016168336A1 (en) 2015-04-14 2016-04-13 Method and system for microbiome-derived characterization, diagnostics, and therapeutics for cardiovascular disease conditions

Publications (2)

Publication Number Publication Date
EP3283649A1 EP3283649A1 (en) 2018-02-21
EP3283649A4 true EP3283649A4 (en) 2019-03-20

Family

ID=57127197

Family Applications (1)

Application Number Title Priority Date Filing Date
EP16780655.3A Pending EP3283649A4 (en) 2015-04-14 2016-04-13 Method and system for microbiome-derived characterization, diagnostics, and therapeutics for cardiovascular disease conditions

Country Status (4)

Country Link
EP (1) EP3283649A4 (en)
CN (1) CN107710205A (en)
AU (2) AU2016248115A1 (en)
WO (1) WO2016168336A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107708714B (en) * 2015-04-14 2022-07-22 普梭梅根公司 Methods and systems for microbiome-derived diagnosis and treatment of endocrine system conditions
KR20200132954A (en) * 2018-03-16 2020-11-25 소마젠 인크 Methods and systems for characterization of metabolic-related conditions, including diagnosis and therapy based on bioinformatics approaches
CN109920478B (en) * 2019-03-07 2020-12-08 中南大学 Microorganism-disease relation prediction method based on similarity and low-rank matrix filling
CN111020038B (en) * 2019-12-30 2023-11-10 南方医科大学南方医院 Intestinal microorganisms, primer set and application for diagnosing heart valve calcification
CN112716504B (en) * 2020-12-22 2023-12-15 沈阳东软智能医疗科技研究院有限公司 Electrocardiogram data processing method and device, storage medium and electronic equipment
CN112509700A (en) * 2021-02-05 2021-03-16 中国医学科学院阜外医院 Stable coronary heart disease risk prediction method and device
CN115851910A (en) * 2022-11-23 2023-03-28 湖州市中心医院 Marker, system and application for diagnosing or predicting coronary heart disease

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130052172A1 (en) * 2011-08-26 2013-02-28 John Edward Baker Methods for diagnosing and treating cardiac defects
WO2014053608A1 (en) * 2012-10-03 2014-04-10 Metabogen Ab Identification of a person having risk for atherosclerosis and associated diseases by the person's gut microbiome and the prevention of such diseases

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPR101600A0 (en) * 2000-10-25 2000-11-16 Atheromastat Pty Ltd Compositions and methods for diagnosis and treatment of cardiovascular disorders
US20100191141A1 (en) * 2009-01-27 2010-07-29 Peter Aberg Method and apparatus for diagnosing a diseased condition in tissue of a subject
US20120129794A1 (en) * 2009-07-24 2012-05-24 Dowd Scot E Apparati, methods, and compositions for universal microbial diagnosis, detection, quantification, and specimen-targeted therapy
CA2783536A1 (en) * 2009-12-09 2011-06-16 Aviir, Inc. Biomarker assay for diagnosis and classification of cardiovascular disease
WO2012050513A1 (en) * 2010-10-11 2012-04-19 Baeckhed Fredrik Method for identifying a risk of cardiovascular disease by analysing oral microbiota
US10633714B2 (en) * 2013-07-21 2020-04-28 Pendulum Therapeutics, Inc. Methods and systems for microbiome characterization, monitoring and treatment
US9663831B2 (en) * 2014-01-25 2017-05-30 uBiome, Inc. Method and system for microbiome analysis
CN104032016B (en) * 2014-06-12 2016-03-30 山东农业大学 A kind of chicken intestinal diorder Salmonella infection is correlated with the detection method of microRNA

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130052172A1 (en) * 2011-08-26 2013-02-28 John Edward Baker Methods for diagnosing and treating cardiac defects
WO2014053608A1 (en) * 2012-10-03 2014-04-10 Metabogen Ab Identification of a person having risk for atherosclerosis and associated diseases by the person's gut microbiome and the prevention of such diseases

Also Published As

Publication number Publication date
AU2022203346A1 (en) 2022-06-09
AU2016248115A1 (en) 2017-11-09
EP3283649A1 (en) 2018-02-21
WO2016168336A1 (en) 2016-10-20
CN107710205A (en) 2018-02-16

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