EP3283060A4 - Compositions, composés bolaamphiphiles, et leurs utilisations - Google Patents

Compositions, composés bolaamphiphiles, et leurs utilisations Download PDF

Info

Publication number
EP3283060A4
EP3283060A4 EP16780822.9A EP16780822A EP3283060A4 EP 3283060 A4 EP3283060 A4 EP 3283060A4 EP 16780822 A EP16780822 A EP 16780822A EP 3283060 A4 EP3283060 A4 EP 3283060A4
Authority
EP
European Patent Office
Prior art keywords
compositions
bolaamphiphilic compounds
bolaamphiphilic
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP16780822.9A
Other languages
German (de)
English (en)
Other versions
EP3283060A1 (fr
Inventor
Charles Linder
Eliahu Heldman
Sarina Grinberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lauren Sciences LLC
Original Assignee
Lauren Sciences LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lauren Sciences LLC filed Critical Lauren Sciences LLC
Publication of EP3283060A1 publication Critical patent/EP3283060A1/fr
Publication of EP3283060A4 publication Critical patent/EP3283060A4/fr
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
EP16780822.9A 2015-04-16 2016-04-15 Compositions, composés bolaamphiphiles, et leurs utilisations Pending EP3283060A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562148511P 2015-04-16 2015-04-16
US201562258773P 2015-11-23 2015-11-23
PCT/US2016/027726 WO2016168580A1 (fr) 2015-04-16 2016-04-15 Compositions, composés bolaamphiphiles, et leurs utilisations

Publications (2)

Publication Number Publication Date
EP3283060A1 EP3283060A1 (fr) 2018-02-21
EP3283060A4 true EP3283060A4 (fr) 2018-12-19

Family

ID=57126121

Family Applications (1)

Application Number Title Priority Date Filing Date
EP16780822.9A Pending EP3283060A4 (fr) 2015-04-16 2016-04-15 Compositions, composés bolaamphiphiles, et leurs utilisations

Country Status (5)

Country Link
EP (1) EP3283060A4 (fr)
AU (1) AU2016248992A1 (fr)
CA (1) CA3018945A1 (fr)
IL (1) IL255042B (fr)
WO (1) WO2016168580A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230026946A1 (en) * 2020-11-03 2023-01-26 Onconano Medicine, Inc. Therapeutic ph responsive compositions

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014039504A1 (fr) * 2012-09-04 2014-03-13 Lauren Sciences Llc Composés bolaamphiphiles, compositions et leurs utilisations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2010245629A1 (en) * 2009-05-04 2012-01-12 Ben-Gurion University Of The Negev Research And Development Authority Nano-sized particles comprising multi-headed amphiphiles for targeted drug delivery
EP2892510A4 (fr) * 2012-09-04 2016-06-01 Lauren Sciences Llc Composés bolaamphiphiles, compositions et leurs utilisations
EP2892511B1 (fr) * 2012-09-04 2021-06-30 Lauren Sciences LLC Composés bolaamphiphiles, compositions et leurs utilisations

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014039504A1 (fr) * 2012-09-04 2014-03-13 Lauren Sciences Llc Composés bolaamphiphiles, compositions et leurs utilisations

Also Published As

Publication number Publication date
EP3283060A1 (fr) 2018-02-21
IL255042B (en) 2022-04-01
IL255042A0 (en) 2017-12-31
AU2016248992A1 (en) 2017-12-07
CA3018945A1 (fr) 2016-10-20
WO2016168580A1 (fr) 2016-10-20

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