EP3200152A3 - Beurteilung von coregistrierten Bildern von verschieden gefärbten Gewebeschnitten - Google Patents

Beurteilung von coregistrierten Bildern von verschieden gefärbten Gewebeschnitten Download PDF

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Publication number
EP3200152A3
EP3200152A3 EP17161436.5A EP17161436A EP3200152A3 EP 3200152 A3 EP3200152 A3 EP 3200152A3 EP 17161436 A EP17161436 A EP 17161436A EP 3200152 A3 EP3200152 A3 EP 3200152A3
Authority
EP
European Patent Office
Prior art keywords
image
frame
tissue
evaluation
tissue slices
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP17161436.5A
Other languages
English (en)
French (fr)
Other versions
EP3200152A2 (de
Inventor
Ralf Schönmeyer
Gerd Binnig
Günter Schmidt
Maria Athelogou
Peter Ellenberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Definiens AG
Original Assignee
Definiens AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Definiens AG filed Critical Definiens AG
Publication of EP3200152A2 publication Critical patent/EP3200152A2/de
Publication of EP3200152A3 publication Critical patent/EP3200152A3/de
Ceased legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06VIMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00Scenes; Scene-specific elements
    • G06V20/60Type of objects
    • G06V20/69Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/695Preprocessing, e.g. image segmentation
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/30Determination of transform parameters for the alignment of images, i.e. image registration
    • G06T7/33Determination of transform parameters for the alignment of images, i.e. image registration using feature-based methods
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00ICT specially adapted for the handling or processing of medical images
    • G16H30/40ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10056Microscopic image
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30024Cell structures in vitro; Tissue sections in vitro

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  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Multimedia (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Primary Health Care (AREA)
  • Public Health (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
EP17161436.5A 2011-12-20 2012-12-18 Beurteilung von coregistrierten Bildern von verschieden gefärbten Gewebeschnitten Ceased EP3200152A3 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/330,900 US9740912B2 (en) 2011-12-20 2011-12-20 Evaluation of co-registered images of differently stained tissue slices
EP12197658.3A EP2608150A3 (de) 2011-12-20 2012-12-18 Beurteilung von coregistrierten Bildern von verschieden gefärbten Gewebeschnitten

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
EP12197658.3A Division EP2608150A3 (de) 2011-12-20 2012-12-18 Beurteilung von coregistrierten Bildern von verschieden gefärbten Gewebeschnitten

Publications (2)

Publication Number Publication Date
EP3200152A2 EP3200152A2 (de) 2017-08-02
EP3200152A3 true EP3200152A3 (de) 2017-10-25

Family

ID=47594396

Family Applications (2)

Application Number Title Priority Date Filing Date
EP17161436.5A Ceased EP3200152A3 (de) 2011-12-20 2012-12-18 Beurteilung von coregistrierten Bildern von verschieden gefärbten Gewebeschnitten
EP12197658.3A Withdrawn EP2608150A3 (de) 2011-12-20 2012-12-18 Beurteilung von coregistrierten Bildern von verschieden gefärbten Gewebeschnitten

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP12197658.3A Withdrawn EP2608150A3 (de) 2011-12-20 2012-12-18 Beurteilung von coregistrierten Bildern von verschieden gefärbten Gewebeschnitten

Country Status (2)

Country Link
US (2) US9740912B2 (de)
EP (2) EP3200152A3 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8977017B2 (en) * 2011-09-15 2015-03-10 The General Hospital Corporation System and method for support of medical diagnosis
US9230185B1 (en) * 2012-03-30 2016-01-05 Pierce Biotechnology, Inc. Analysis of electrophoretic bands in a substrate
US20130286043A1 (en) * 2012-04-30 2013-10-31 General Electric Company Systems and methods for analyzing biomarker co-localization in a biological tissue
JP6187989B2 (ja) * 2012-04-30 2017-08-30 ゼネラル・エレクトリック・カンパニイ 生物組織に共局在するバイオマーカーを解析するためのシステム及び方法
US8928730B2 (en) 2012-07-03 2015-01-06 DigitalOptics Corporation Europe Limited Method and system for correcting a distorted input image
US9242602B2 (en) 2012-08-27 2016-01-26 Fotonation Limited Rearview imaging systems for vehicle
DE102013107301A1 (de) * 2013-07-10 2015-01-15 microDimensions GmbH Verfahren zur Bildregistrierung
EP3053139B1 (de) * 2013-10-01 2020-10-21 Ventana Medical Systems, Inc. Vollschnittbildregistrierung und bildübergreifende annotationsvorrichtungen, -systeme und -verfahren
CA2942081C (en) * 2013-10-11 2021-09-07 Ventana Medical Systems, Inc. Multiplex her2 and estrogen receptor co-staining assays for detecting tumor heterogeneity
WO2015112804A1 (en) * 2014-01-23 2015-07-30 The General Hospital Corporation System and method for generating magnetic resonance imaging (mri) images using structures of the images
US10096110B2 (en) * 2014-08-22 2018-10-09 University Of South Florida System and method for automated stereology of cancer
WO2017013045A1 (en) 2015-07-17 2017-01-26 Koninklijke Philips N.V. Registration of histopathology images
US9779499B2 (en) * 2015-09-18 2017-10-03 Definiens Ag Grading of glandular tissue cancer by detailed image analysis of stained tissue slices
US9779293B2 (en) * 2016-01-27 2017-10-03 Honeywell International Inc. Method and tool for post-mortem analysis of tripped field devices in process industry using optical character recognition and intelligent character recognition
US9990713B2 (en) 2016-06-09 2018-06-05 Definiens Ag Detecting and visualizing correlations between measured correlation values and correlation reference values of a pathway
JP6670222B2 (ja) * 2016-11-01 2020-03-18 株式会社日立ハイテク 画像診断支援装置及びシステム、画像診断支援方法
US11170897B2 (en) 2017-02-23 2021-11-09 Google Llc Method and system for assisting pathologist identification of tumor cells in magnified tissue images
WO2019108230A1 (en) * 2017-12-01 2019-06-06 Flagship Biosciences Inc. Method for scoring pathology images using spatial analysis of tissues
WO2019126112A1 (en) * 2017-12-19 2019-06-27 Albert Einstein College Of Medicine, Inc. Combined markers for metastatic cancer and uses thereof
EP3640837A1 (de) * 2018-10-15 2020-04-22 Koninklijke Philips N.V. System zur co-registrierung von medizinischen bildern mithilfe eines klassifikators
EP3761032A1 (de) * 2019-07-03 2021-01-06 Xyall B.V. Bestimmung der region(en) für gewebedissektion in gewebeschnitten
CN111260699B (zh) * 2019-12-30 2024-02-06 上海镜观生物科技有限公司 高清病理影像配准方法、装置、设备及存储介质
CN111430011B (zh) * 2020-03-31 2023-08-29 杭州依图医疗技术有限公司 细胞染色图像的显示方法、处理方法及存储介质
CN113781530B (zh) * 2021-10-09 2024-03-19 上海衡道医学病理诊断中心有限公司 一种染色切片的图像配准方法及系统
JP7752527B2 (ja) * 2021-12-28 2025-10-10 株式会社Screenホールディングス 画像表示方法、コンピュータープログラムおよび記録媒体
CN115508352A (zh) * 2022-09-20 2022-12-23 中国人民解放军陆军军医大学第二附属医院 一种切片图像的显示装置及设备
TWI838199B (zh) * 2023-03-31 2024-04-01 慧術科技股份有限公司 醫學靜態圖片對照教學系統及其方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080032328A1 (en) * 2006-08-07 2008-02-07 General Electric Company System and method for co-registering multi-channel images of a tissue micro array
US20110128299A1 (en) * 2009-11-30 2011-06-02 Sony Corporation Information processing apparatus, method, and computer-readable medium

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6243095B1 (en) * 1996-12-05 2001-06-05 Peter E. Shile Navigation and display system for digital radiographs
JPH10267628A (ja) * 1997-01-23 1998-10-09 Hitachi Ltd 3次元形状検出方法およびその装置並びに基板の製造方法
US7249317B1 (en) * 1999-09-27 2007-07-24 Canon Kabushiki Kaisha Information processing apparatus, its control method, and storage medium
JP4673000B2 (ja) 2004-05-21 2011-04-20 株式会社キーエンス 蛍光顕微鏡、蛍光顕微鏡装置を使用した表示方法、蛍光顕微鏡画像表示プログラム及びコンピュータで読み取り可能な記録媒体並びに記憶した機器
JP4186878B2 (ja) * 2004-06-08 2008-11-26 ソニー株式会社 動画像再生装置,動画像再生方法,プログラム及びその記録媒体
US7382919B2 (en) 2006-06-22 2008-06-03 Xerox Corporation System and method for editing image data
CN101542527A (zh) 2006-11-16 2009-09-23 维斯欧法姆有限公司 可组合图像的基于特征的配准
US8369600B2 (en) * 2008-03-25 2013-02-05 General Electric Company Method and apparatus for detecting irregularities in tissue microarrays
JP4577410B2 (ja) * 2008-06-18 2010-11-10 ソニー株式会社 画像処理装置、画像処理方法およびプログラム
US8557527B2 (en) * 2008-09-22 2013-10-15 Historx, Inc. Correlation of molecular markers with clinical outcome in GBM patients radiation treated with or without gefitinib
WO2011163391A2 (en) * 2010-06-22 2011-12-29 The Johns Hopkins University Atlas-based analysis for image-based anatomic and functional data of organism
WO2012001648A2 (en) * 2010-06-30 2012-01-05 Medic Vision - Imaging Solutions Ltd. Non-linear resolution reduction for medical imagery
US20120179665A1 (en) * 2011-01-07 2012-07-12 Access Business Group International Llc Health monitoring system

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080032328A1 (en) * 2006-08-07 2008-02-07 General Electric Company System and method for co-registering multi-channel images of a tissue micro array
US20110128299A1 (en) * 2009-11-30 2011-06-02 Sony Corporation Information processing apparatus, method, and computer-readable medium

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ARGANDA-CARRERAS I ET AL: "Automatic registration of serial mammary gland sections", PROCEEDINGS OF THE 26TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE EMBS SAN FRANCISCO,CA, IEEE SERVICE CENTER, PISCATAWAY, NJ, vol. 3, 1 September 2004 (2004-09-01), pages 1691, XP010775280, ISBN: 978-0-7803-8439-2, DOI: 10.1109/IEMBS.2004.1403509 *
YUAN ZHEN-MING ET AL: "Multi-sensor image registration using multi-resolution shape analysis", JOURNAL OF ZHEJIANG UNIVERSITY SCIENCE A, ZHEIJIANG UNIVERSITY PRESS, CN, vol. 7, no. 4, 14 March 2006 (2006-03-14), pages 549 - 555, XP036040674, ISSN: 1673-565X, [retrieved on 20060314], DOI: 10.1631/JZUS.2006.A0549 *

Also Published As

Publication number Publication date
US9740912B2 (en) 2017-08-22
EP3200152A2 (de) 2017-08-02
US10262189B2 (en) 2019-04-16
EP2608150A2 (de) 2013-06-26
EP2608150A3 (de) 2014-09-24
US20170372118A1 (en) 2017-12-28
US20130156279A1 (en) 2013-06-20

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