EP3137628A4 - Verfahren zur vorhersage von medizinisch refraktiver colitis ulcerosa (mruc) mit erforderlicher kolektomie - Google Patents
Verfahren zur vorhersage von medizinisch refraktiver colitis ulcerosa (mruc) mit erforderlicher kolektomie Download PDFInfo
- Publication number
- EP3137628A4 EP3137628A4 EP15785256.7A EP15785256A EP3137628A4 EP 3137628 A4 EP3137628 A4 EP 3137628A4 EP 15785256 A EP15785256 A EP 15785256A EP 3137628 A4 EP3137628 A4 EP 3137628A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- mruc
- predicting
- methods
- ulcerative colitis
- medically refractive
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461988078P | 2014-05-02 | 2014-05-02 | |
PCT/US2015/029101 WO2015168699A1 (en) | 2014-05-02 | 2015-05-04 | Methods of predicting medically refractive ulcerative colitis (mruc) requiring colectomy |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3137628A1 EP3137628A1 (de) | 2017-03-08 |
EP3137628A4 true EP3137628A4 (de) | 2018-03-21 |
Family
ID=54359430
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP15785256.7A Withdrawn EP3137628A4 (de) | 2014-05-02 | 2015-05-04 | Verfahren zur vorhersage von medizinisch refraktiver colitis ulcerosa (mruc) mit erforderlicher kolektomie |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP3137628A4 (de) |
CA (1) | CA2946317A1 (de) |
WO (1) | WO2015168699A1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010062960A2 (en) | 2008-11-26 | 2010-06-03 | Cedars-Sinai Medical Center | METHODS OF DETERMINING RESPONSIVENESS TO ANTI-TNFα THERAPY IN INFLAMMATORY BOWEL DISEASE |
US9580752B2 (en) | 2008-12-24 | 2017-02-28 | Cedars-Sinai Medical Center | Methods of predicting medically refractive ulcerative colitis (MR-UC) requiring colectomy |
BR112015024752A2 (pt) | 2013-03-27 | 2017-07-18 | Cedars Sinai Medical Center | mitigação e reversão da fibrose e inflamação através da inibição da função de tl1a e vias de sinalização relacionadas |
WO2015010108A1 (en) | 2013-07-19 | 2015-01-22 | Cedars-Sinai Medical Center | Signature of tl1a (tnfsf15) signaling pathway |
US11186872B2 (en) | 2016-03-17 | 2021-11-30 | Cedars-Sinai Medical Center | Methods of diagnosing inflammatory bowel disease through RNASET2 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20120053131A1 (en) * | 2008-12-24 | 2012-03-01 | Cedars-Sinai Medical Center | Methods of predicting medically refractive ulcerative colitis (mr-uc) requiring colectomy |
CN103149371A (zh) * | 2013-02-26 | 2013-06-12 | 哈药慈航制药股份有限公司 | 生物标记物在制备预测5-氨基水杨酸治疗溃疡性结肠炎的反馈响应药物中的应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100015156A1 (en) * | 2007-03-06 | 2010-01-21 | Cedars-Sinai Medical Center | Diagnosis of inflammatory bowel disease in children |
EP2757160A3 (de) * | 2009-07-20 | 2014-07-30 | Genentech, Inc. | Genexpressionsmarker für Morbus Crohn |
WO2012071436A1 (en) * | 2010-11-24 | 2012-05-31 | Genentech, Inc. | Method of treating autoimmune inflammatory disorders using il-23r loss-of-function mutants |
-
2015
- 2015-05-04 WO PCT/US2015/029101 patent/WO2015168699A1/en active Application Filing
- 2015-05-04 CA CA2946317A patent/CA2946317A1/en not_active Abandoned
- 2015-05-04 EP EP15785256.7A patent/EP3137628A4/de not_active Withdrawn
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20120053131A1 (en) * | 2008-12-24 | 2012-03-01 | Cedars-Sinai Medical Center | Methods of predicting medically refractive ulcerative colitis (mr-uc) requiring colectomy |
CN103149371A (zh) * | 2013-02-26 | 2013-06-12 | 哈药慈航制药股份有限公司 | 生物标记物在制备预测5-氨基水杨酸治疗溃疡性结肠炎的反馈响应药物中的应用 |
Non-Patent Citations (2)
Title |
---|
See also references of WO2015168699A1 * |
TALIN HARITUNIANS ET AL: "Genetic predictors of medically refractory ulcerative colitis :", INFLAMMATORY BOWEL DISEASES, vol. 16, no. 11, 1 November 2010 (2010-11-01), US, pages 1830 - 1840, XP055419882, ISSN: 1078-0998, DOI: 10.1002/ibd.21293 * |
Also Published As
Publication number | Publication date |
---|---|
EP3137628A1 (de) | 2017-03-08 |
WO2015168699A1 (en) | 2015-11-05 |
CA2946317A1 (en) | 2015-11-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20161108 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
AX | Request for extension of the european patent |
Extension state: BA ME |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: TARGAN, STEPHAN Inventor name: MCGOVERN, DERMOT P. Inventor name: FLESHNER, PHILIP Inventor name: HARITUNIANS, TALIN |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: HARITUNIANS, TALIN Inventor name: TARGAN, STEPHAN Inventor name: MCGOVERN, DERMOT P. Inventor name: FLESHNER, PHILIP |
|
DAV | Request for validation of the european patent (deleted) | ||
DAX | Request for extension of the european patent (deleted) | ||
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12Q 1/68 20060101AFI20171108BHEP |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20180219 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12Q 1/68 20180101AFI20180213BHEP |
|
17Q | First examination report despatched |
Effective date: 20190117 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20190730 |