EP3083580A4 - A process for preparation of trelagliptin succinate - Google Patents
A process for preparation of trelagliptin succinate Download PDFInfo
- Publication number
- EP3083580A4 EP3083580A4 EP14871930.5A EP14871930A EP3083580A4 EP 3083580 A4 EP3083580 A4 EP 3083580A4 EP 14871930 A EP14871930 A EP 14871930A EP 3083580 A4 EP3083580 A4 EP 3083580A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- preparation
- trelagliptin succinate
- trelagliptin
- succinate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN3964MU2013 | 2013-12-18 | ||
PCT/IN2014/000563 WO2015092805A1 (en) | 2013-12-18 | 2014-09-01 | A process for preparation of trelagliptin succinate |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3083580A1 EP3083580A1 (en) | 2016-10-26 |
EP3083580A4 true EP3083580A4 (en) | 2017-06-28 |
Family
ID=53402222
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP14871930.5A Withdrawn EP3083580A4 (en) | 2013-12-18 | 2014-09-01 | A process for preparation of trelagliptin succinate |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP3083580A4 (en) |
WO (1) | WO2015092805A1 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105646447A (en) * | 2015-12-25 | 2016-06-08 | 北京康立生医药技术开发有限公司 | Synthesis method of dipeptidyl peptidase inhibitor |
CN105541793B (en) * | 2016-01-04 | 2018-08-10 | 河北国龙制药有限公司 | The synthetic method of bent Ge Lieting |
CN107434800A (en) * | 2016-05-27 | 2017-12-05 | 威海迪素制药有限公司 | A kind of amber love song Ge Lieting crystal formations A preparation method |
CN108822080A (en) * | 2018-08-31 | 2018-11-16 | 四川新斯顿制药股份有限公司 | The preparation method of amber love song Ge Lieting |
CN109668988B (en) * | 2019-02-27 | 2021-07-02 | 浙江华贝药业有限责任公司 | Method for analyzing and determining 2- (dibromomethyl) -4-fluorobenzonitrile in trelagliptin succinate |
CN109734673A (en) * | 2019-02-27 | 2019-05-10 | 浙江华贝药业有限责任公司 | A kind of purification process of compound |
CN110483478B (en) * | 2019-08-15 | 2021-07-06 | 广东工业大学 | Crystalline trelagliptin, preparation method and application thereof, trelagliptin succinate crystal and preparation method thereof |
CN115448887A (en) * | 2022-09-05 | 2022-12-09 | 河北国龙制药有限公司 | Trelagliptin succinate intermediate impurity and preparation method and application thereof |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090275750A1 (en) * | 2005-09-16 | 2009-11-05 | Jun Feng | Dipeptidyl peptidase inhibitors |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ549716A (en) * | 2004-03-15 | 2010-04-30 | Takeda Pharmaceutical | Pyrimidin-dione derivatives as dipeptidyl peptidase inhibitors |
TW200838536A (en) * | 2006-11-29 | 2008-10-01 | Takeda Pharmaceutical | Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor |
US8093236B2 (en) * | 2007-03-13 | 2012-01-10 | Takeda Pharmaceuticals Company Limited | Weekly administration of dipeptidyl peptidase inhibitors |
CN103030631B (en) * | 2011-09-28 | 2014-12-10 | 正大天晴药业集团股份有限公司 | Compound for preparing pyrimidinedione DPP-IV (dipeptidyl peptidase IV) inhibitors |
-
2014
- 2014-09-01 WO PCT/IN2014/000563 patent/WO2015092805A1/en active Application Filing
- 2014-09-01 EP EP14871930.5A patent/EP3083580A4/en not_active Withdrawn
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090275750A1 (en) * | 2005-09-16 | 2009-11-05 | Jun Feng | Dipeptidyl peptidase inhibitors |
Non-Patent Citations (1)
Title |
---|
See also references of WO2015092805A1 * |
Also Published As
Publication number | Publication date |
---|---|
WO2015092805A1 (en) | 2015-06-25 |
EP3083580A1 (en) | 2016-10-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20160701 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
AX | Request for extension of the european patent |
Extension state: BA ME |
|
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20170526 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C07D 401/04 20060101AFI20170519BHEP |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20180103 |