EP3058103A4 - Détection et surveillance de mutations d'histiocytose - Google Patents

Détection et surveillance de mutations d'histiocytose Download PDF

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Publication number
EP3058103A4
EP3058103A4 EP14853756.6A EP14853756A EP3058103A4 EP 3058103 A4 EP3058103 A4 EP 3058103A4 EP 14853756 A EP14853756 A EP 14853756A EP 3058103 A4 EP3058103 A4 EP 3058103A4
Authority
EP
European Patent Office
Prior art keywords
histiocytosis
detecting
mutations
monitoring
monitoring mutations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14853756.6A
Other languages
German (de)
English (en)
Other versions
EP3058103A2 (fr
Inventor
Filip JANKU
Mark G. Erlander
Cecile Rose VIBAT
Karena Kosco
Omar Abdel-Wahab
Eli L. DIAMOND
David M. HYMAN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cardiff Oncology Inc
Original Assignee
Trovagene Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trovagene Inc filed Critical Trovagene Inc
Publication of EP3058103A2 publication Critical patent/EP3058103A2/fr
Publication of EP3058103A4 publication Critical patent/EP3058103A4/fr
Withdrawn legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP14853756.6A 2013-10-19 2014-10-18 Détection et surveillance de mutations d'histiocytose Withdrawn EP3058103A4 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361893218P 2013-10-19 2013-10-19
US201461977611P 2014-04-09 2014-04-09
US201462006261P 2014-06-01 2014-06-01
US201462040366P 2014-08-21 2014-08-21
PCT/US2014/061281 WO2015058175A2 (fr) 2013-10-19 2014-10-18 Détection et surveillance de mutations d'histiocytose

Publications (2)

Publication Number Publication Date
EP3058103A2 EP3058103A2 (fr) 2016-08-24
EP3058103A4 true EP3058103A4 (fr) 2017-05-17

Family

ID=52828866

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14853756.6A Withdrawn EP3058103A4 (fr) 2013-10-19 2014-10-18 Détection et surveillance de mutations d'histiocytose

Country Status (4)

Country Link
EP (1) EP3058103A4 (fr)
HK (1) HK1222206A1 (fr)
IL (1) IL244733A0 (fr)
WO (1) WO2015058175A2 (fr)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008106453A2 (fr) * 2007-02-26 2008-09-04 John Wayne Cancer Institute Utilité de la mutation d'adn de b-raf dans le diagnostic et le traitement d'un cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009049147A2 (fr) * 2007-10-10 2009-04-16 Philadelphia Health & Education Corporation D/B/A Drexel University College Of Medicine Procédé de dépistage des tumeurs
EP2771486A1 (fr) * 2011-10-24 2014-09-03 Trovagene, Inc. Procédé de détection de mutations du gène braf dans des cancers

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008106453A2 (fr) * 2007-02-26 2008-09-04 John Wayne Cancer Institute Utilité de la mutation d'adn de b-raf dans le diagnostic et le traitement d'un cancer

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
ALAIN R THIERRY ET AL: "Clinical validation of the detection of KRAS and BRAF mutations from circulating tumor DNA", vol. 20, no. 4, 1 April 2014 (2014-04-01), pages 430 - 435, XP002730498, ISSN: 1078-8956, Retrieved from the Internet <URL:http://www.nature.com/nm/journal/v20/n4/full/nm.3511.html> [retrieved on 20140323], DOI: 10.1038/NM.3511 *
DIAMOND ELI ET AL.,: "Detection of an NRAS mutation in Erdheim-Chester disease", BLOOD, 8 August 2013 (2013-08-08), United States, pages 1089, XP055362342, Retrieved from the Internet <URL:http://www.bloodjournal.org/content/bloodjournal/122/6/1089.full.pdf> *
FILIP JANKU ET AL: "BRAF V600E mutations in urine and plasma cell-free DNA from patients with Erdheim-Chester disease", ONCOTARGET, vol. 5, no. 11, 13 May 2014 (2014-05-13), United States, pages 3607 - 3610, XP055153092, DOI: 10.18632/oncotarget.1964 *
G. BADALIAN-VERY ET AL: "Recurrent BRAF mutations in Langerhans cell histiocytosis", BLOOD, vol. 116, no. 11, 16 September 2010 (2010-09-16), pages 1919 - 1923, XP055027891, ISSN: 0006-4971, DOI: 10.1182/blood-2010-04-279083 *
J. HAROCHE ET AL: "High prevalence of BRAF V600E mutations in Erdheim-Chester disease but not in other non-Langerhans cell histiocytoses", BLOOD, vol. 120, no. 13, 9 August 2012 (2012-08-09), & 53RD ANNUAL MEETING AND EXPOSITION OF THE AMERICAN-SOCIETY-OF-HEMATOLOGY (ASH); SAN DIEGO, CA, USA; DECEMBER 10 -13, 2011, pages 2700 - 2703, XP055362341, ISSN: 0006-4971, DOI: 10.1182/blood-2012-05-430140 *
TAKESHI SATOH ET AL: "B-RAF Mutant Alleles Associated with Langerhans Cell Histiocytosis, a Granulomatous Pediatric Disease", PLOS ONE, vol. 7, no. 4, 10 April 2012 (2012-04-10), pages e33891, XP055362288, DOI: 10.1371/journal.pone.0033891 *
THIERRY LECOMTE ET AL: "Detection of free-circulating tumor-associated DNA in plasma of colorectal cancer patients and its association with prognosis", INTERNATIONAL JOURNAL OF CANCER, vol. 100, no. 5, 10 August 2002 (2002-08-10), pages 542 - 548, XP055071717, ISSN: 0020-7136, DOI: 10.1002/ijc.10526 *

Also Published As

Publication number Publication date
WO2015058175A2 (fr) 2015-04-23
WO2015058175A3 (fr) 2015-06-25
HK1222206A1 (zh) 2017-06-23
EP3058103A2 (fr) 2016-08-24
IL244733A0 (en) 2016-04-21

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