EP3022280A1 - Mild alkaline solid instrument cleaner - Google Patents
Mild alkaline solid instrument cleanerInfo
- Publication number
- EP3022280A1 EP3022280A1 EP13739990.3A EP13739990A EP3022280A1 EP 3022280 A1 EP3022280 A1 EP 3022280A1 EP 13739990 A EP13739990 A EP 13739990A EP 3022280 A1 EP3022280 A1 EP 3022280A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- preferred
- mild alkaline
- solution
- salts
- cleaning composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000007787 solid Substances 0.000 title claims abstract description 99
- 238000004140 cleaning Methods 0.000 claims abstract description 191
- 239000000203 mixture Substances 0.000 claims abstract description 182
- 229920001223 polyethylene glycol Polymers 0.000 claims abstract description 66
- 239000002202 Polyethylene glycol Substances 0.000 claims abstract description 65
- 229910052751 metal Inorganic materials 0.000 claims abstract description 60
- 239000002184 metal Substances 0.000 claims abstract description 60
- 239000003112 inhibitor Substances 0.000 claims abstract description 59
- 238000005260 corrosion Methods 0.000 claims abstract description 49
- 230000007797 corrosion Effects 0.000 claims abstract description 49
- 238000012545 processing Methods 0.000 claims abstract description 19
- 239000000243 solution Substances 0.000 claims description 87
- 239000007788 liquid Substances 0.000 claims description 84
- 150000003839 salts Chemical class 0.000 claims description 53
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 52
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 49
- 229910001868 water Inorganic materials 0.000 claims description 48
- 229920003023 plastic Polymers 0.000 claims description 30
- 239000004033 plastic Substances 0.000 claims description 30
- 239000002904 solvent Substances 0.000 claims description 25
- 239000003352 sequestering agent Substances 0.000 claims description 23
- -1 diethanolglycine sodium salt Chemical class 0.000 claims description 22
- PMYUVOOOQDGQNW-UHFFFAOYSA-N hexasodium;trioxido(trioxidosilyloxy)silane Chemical compound [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[O-][Si]([O-])([O-])O[Si]([O-])([O-])[O-] PMYUVOOOQDGQNW-UHFFFAOYSA-N 0.000 claims description 22
- QRUDEWIWKLJBPS-UHFFFAOYSA-N benzotriazole Chemical compound C1=CC=C2N[N][N]C2=C1 QRUDEWIWKLJBPS-UHFFFAOYSA-N 0.000 claims description 19
- 229920000642 polymer Polymers 0.000 claims description 18
- 239000013078 crystal Substances 0.000 claims description 15
- 239000003607 modifier Substances 0.000 claims description 15
- SVTBMSDMJJWYQN-UHFFFAOYSA-N 2-methylpentane-2,4-diol Chemical compound CC(O)CC(C)(C)O SVTBMSDMJJWYQN-UHFFFAOYSA-N 0.000 claims description 14
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 12
- UZVUJVFQFNHRSY-OUTKXMMCSA-J tetrasodium;(2s)-2-[bis(carboxylatomethyl)amino]pentanedioate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CC[C@@H](C([O-])=O)N(CC([O-])=O)CC([O-])=O UZVUJVFQFNHRSY-OUTKXMMCSA-J 0.000 claims description 11
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 10
- 229920002125 Sokalan® Polymers 0.000 claims description 10
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 9
- 150000001412 amines Chemical class 0.000 claims description 9
- 239000007864 aqueous solution Substances 0.000 claims description 9
- URDCARMUOSMFFI-UHFFFAOYSA-N 2-[2-[bis(carboxymethyl)amino]ethyl-(2-hydroxyethyl)amino]acetic acid Chemical class OCCN(CC(O)=O)CCN(CC(O)=O)CC(O)=O URDCARMUOSMFFI-UHFFFAOYSA-N 0.000 claims description 8
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical class OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims description 8
- 239000002253 acid Substances 0.000 claims description 8
- 229960001484 edetic acid Drugs 0.000 claims description 8
- 239000004584 polyacrylic acid Substances 0.000 claims description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 7
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 claims description 7
- 229940051250 hexylene glycol Drugs 0.000 claims description 7
- WMFOQBRAJBCJND-UHFFFAOYSA-M Lithium hydroxide Chemical compound [Li+].[OH-] WMFOQBRAJBCJND-UHFFFAOYSA-M 0.000 claims description 6
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims description 6
- 150000001732 carboxylic acid derivatives Chemical class 0.000 claims description 6
- MWKFXSUHUHTGQN-UHFFFAOYSA-N decan-1-ol Chemical compound CCCCCCCCCCO MWKFXSUHUHTGQN-UHFFFAOYSA-N 0.000 claims description 6
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 claims description 6
- MGFYIUFZLHCRTH-UHFFFAOYSA-N nitrilotriacetic acid Chemical class OC(=O)CN(CC(O)=O)CC(O)=O MGFYIUFZLHCRTH-UHFFFAOYSA-N 0.000 claims description 6
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 claims description 5
- 150000001875 compounds Chemical class 0.000 claims description 5
- 235000011187 glycerol Nutrition 0.000 claims description 5
- 239000008247 solid mixture Substances 0.000 claims description 5
- POAOYUHQDCAZBD-UHFFFAOYSA-N 2-butoxyethanol Chemical compound CCCCOCCO POAOYUHQDCAZBD-UHFFFAOYSA-N 0.000 claims description 4
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 4
- ZTVCAEHRNBOTLI-UHFFFAOYSA-L Glycine, N-(carboxymethyl)-N-(2-hydroxyethyl)-, disodium salt Chemical class [Na+].[Na+].OCCN(CC([O-])=O)CC([O-])=O ZTVCAEHRNBOTLI-UHFFFAOYSA-L 0.000 claims description 4
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims description 4
- 150000001298 alcohols Chemical class 0.000 claims description 4
- 239000012964 benzotriazole Substances 0.000 claims description 4
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 claims description 4
- 239000005968 1-Decanol Substances 0.000 claims description 3
- QGJDXUIYIUGQGO-UHFFFAOYSA-N 1-[2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]pyrrolidine-2-carboxylic acid Chemical compound CC(C)(C)OC(=O)NC(C)C(=O)N1CCCC1C(O)=O QGJDXUIYIUGQGO-UHFFFAOYSA-N 0.000 claims description 3
- AEQDJSLRWYMAQI-UHFFFAOYSA-N 2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline Chemical compound C1CN2CC(C(=C(OC)C=C3)OC)=C3CC2C2=C1C=C(OC)C(OC)=C2 AEQDJSLRWYMAQI-UHFFFAOYSA-N 0.000 claims description 3
- DBVJJBKOTRCVKF-UHFFFAOYSA-N Etidronic acid Chemical class OP(=O)(O)C(O)(C)P(O)(O)=O DBVJJBKOTRCVKF-UHFFFAOYSA-N 0.000 claims description 3
- QPCDCPDFJACHGM-UHFFFAOYSA-N N,N-bis{2-[bis(carboxymethyl)amino]ethyl}glycine Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(=O)O)CCN(CC(O)=O)CC(O)=O QPCDCPDFJACHGM-UHFFFAOYSA-N 0.000 claims description 3
- 229930195712 glutamate Natural products 0.000 claims description 3
- 150000002334 glycols Chemical class 0.000 claims description 3
- 229960003330 pentetic acid Drugs 0.000 claims description 3
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 claims description 3
- 239000000176 sodium gluconate Substances 0.000 claims description 3
- 235000012207 sodium gluconate Nutrition 0.000 claims description 3
- 229940005574 sodium gluconate Drugs 0.000 claims description 3
- ZIBGPFATKBEMQZ-UHFFFAOYSA-N triethylene glycol Chemical compound OCCOCCOCCO ZIBGPFATKBEMQZ-UHFFFAOYSA-N 0.000 claims description 3
- MARCAKLHFUYDJE-UHFFFAOYSA-N 1,2-xylene;hydrate Chemical compound O.CC1=CC=CC=C1C MARCAKLHFUYDJE-UHFFFAOYSA-N 0.000 claims description 2
- OAYXUHPQHDHDDZ-UHFFFAOYSA-N 2-(2-butoxyethoxy)ethanol Chemical compound CCCCOCCOCCO OAYXUHPQHDHDDZ-UHFFFAOYSA-N 0.000 claims description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims description 2
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims description 2
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 claims description 2
- ABLZXFCXXLZCGV-UHFFFAOYSA-N Phosphorous acid Chemical class OP(O)=O ABLZXFCXXLZCGV-UHFFFAOYSA-N 0.000 claims description 2
- 239000004115 Sodium Silicate Substances 0.000 claims description 2
- UWHCKJMYHZGTIT-UHFFFAOYSA-N Tetraethylene glycol, Natural products OCCOCCOCCOCCO UWHCKJMYHZGTIT-UHFFFAOYSA-N 0.000 claims description 2
- VSGNNIFQASZAOI-UHFFFAOYSA-L calcium acetate Chemical compound [Ca+2].CC([O-])=O.CC([O-])=O VSGNNIFQASZAOI-UHFFFAOYSA-L 0.000 claims description 2
- 239000001639 calcium acetate Substances 0.000 claims description 2
- 235000011092 calcium acetate Nutrition 0.000 claims description 2
- 229960005147 calcium acetate Drugs 0.000 claims description 2
- 229910000019 calcium carbonate Inorganic materials 0.000 claims description 2
- 229960003563 calcium carbonate Drugs 0.000 claims description 2
- 235000010216 calcium carbonate Nutrition 0.000 claims description 2
- 239000001110 calcium chloride Substances 0.000 claims description 2
- 229910001628 calcium chloride Inorganic materials 0.000 claims description 2
- 229960002713 calcium chloride Drugs 0.000 claims description 2
- 235000011148 calcium chloride Nutrition 0.000 claims description 2
- FNAQSUUGMSOBHW-UHFFFAOYSA-H calcium citrate Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O FNAQSUUGMSOBHW-UHFFFAOYSA-H 0.000 claims description 2
- 239000001354 calcium citrate Substances 0.000 claims description 2
- 229960004256 calcium citrate Drugs 0.000 claims description 2
- 239000004227 calcium gluconate Substances 0.000 claims description 2
- 235000013927 calcium gluconate Nutrition 0.000 claims description 2
- 229960004494 calcium gluconate Drugs 0.000 claims description 2
- MKJXYGKVIBWPFZ-UHFFFAOYSA-L calcium lactate Chemical compound [Ca+2].CC(O)C([O-])=O.CC(O)C([O-])=O MKJXYGKVIBWPFZ-UHFFFAOYSA-L 0.000 claims description 2
- 239000001527 calcium lactate Substances 0.000 claims description 2
- 235000011086 calcium lactate Nutrition 0.000 claims description 2
- 229960002401 calcium lactate Drugs 0.000 claims description 2
- 239000001506 calcium phosphate Substances 0.000 claims description 2
- 229910000389 calcium phosphate Inorganic materials 0.000 claims description 2
- 229960001714 calcium phosphate Drugs 0.000 claims description 2
- 235000011010 calcium phosphates Nutrition 0.000 claims description 2
- 229940095672 calcium sulfate Drugs 0.000 claims description 2
- 235000011132 calcium sulphate Nutrition 0.000 claims description 2
- GUPPESBEIQALOS-UHFFFAOYSA-L calcium tartrate Chemical compound [Ca+2].[O-]C(=O)C(O)C(O)C([O-])=O GUPPESBEIQALOS-UHFFFAOYSA-L 0.000 claims description 2
- 239000001427 calcium tartrate Substances 0.000 claims description 2
- 235000011035 calcium tartrate Nutrition 0.000 claims description 2
- NEEHYRZPVYRGPP-UHFFFAOYSA-L calcium;2,3,4,5,6-pentahydroxyhexanoate Chemical compound [Ca+2].OCC(O)C(O)C(O)C(O)C([O-])=O.OCC(O)C(O)C(O)C(O)C([O-])=O NEEHYRZPVYRGPP-UHFFFAOYSA-L 0.000 claims description 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical class OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 claims description 2
- 150000001735 carboxylic acids Chemical class 0.000 claims description 2
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 claims description 2
- 150000002148 esters Chemical class 0.000 claims description 2
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims description 2
- 239000000178 monomer Substances 0.000 claims description 2
- ZJAOAACCNHFJAH-UHFFFAOYSA-N phosphonoformic acid Chemical class OC(=O)P(O)(O)=O ZJAOAACCNHFJAH-UHFFFAOYSA-N 0.000 claims description 2
- 229920001444 polymaleic acid Polymers 0.000 claims description 2
- 229910000029 sodium carbonate Inorganic materials 0.000 claims description 2
- NTHWMYGWWRZVTN-UHFFFAOYSA-N sodium silicate Chemical compound [Na+].[Na+].[O-][Si]([O-])=O NTHWMYGWWRZVTN-UHFFFAOYSA-N 0.000 claims description 2
- 229910052911 sodium silicate Inorganic materials 0.000 claims description 2
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims description 2
- 235000013337 tricalcium citrate Nutrition 0.000 claims description 2
- VLCLHFYFMCKBRP-UHFFFAOYSA-N tricalcium;diborate Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]B([O-])[O-].[O-]B([O-])[O-] VLCLHFYFMCKBRP-UHFFFAOYSA-N 0.000 claims description 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims 4
- 125000002887 hydroxy group Chemical class [H]O* 0.000 claims 1
- 238000000034 method Methods 0.000 abstract description 15
- 239000006260 foam Substances 0.000 description 27
- 238000012360 testing method Methods 0.000 description 21
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 19
- 229910052782 aluminium Inorganic materials 0.000 description 18
- 230000015572 biosynthetic process Effects 0.000 description 18
- 239000012141 concentrate Substances 0.000 description 9
- 150000002739 metals Chemical class 0.000 description 9
- 239000003513 alkali Substances 0.000 description 8
- 150000004760 silicates Chemical class 0.000 description 8
- 239000002689 soil Substances 0.000 description 8
- 239000012670 alkaline solution Substances 0.000 description 5
- 239000008280 blood Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 239000003795 chemical substances by application Substances 0.000 description 5
- 239000008367 deionised water Substances 0.000 description 5
- 229910021641 deionized water Inorganic materials 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 239000011521 glass Substances 0.000 description 5
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 4
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 4
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 4
- 150000008044 alkali metal hydroxides Chemical class 0.000 description 4
- 229920001577 copolymer Polymers 0.000 description 4
- 238000005187 foaming Methods 0.000 description 4
- 239000007921 spray Substances 0.000 description 4
- 238000004659 sterilization and disinfection Methods 0.000 description 4
- 238000010998 test method Methods 0.000 description 4
- 230000004580 weight loss Effects 0.000 description 4
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 3
- 229910014103 Na-S Inorganic materials 0.000 description 3
- 229910014147 Na—S Inorganic materials 0.000 description 3
- 229910019142 PO4 Inorganic materials 0.000 description 3
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 3
- 238000013019 agitation Methods 0.000 description 3
- 238000001816 cooling Methods 0.000 description 3
- 238000004090 dissolution Methods 0.000 description 3
- 239000011777 magnesium Substances 0.000 description 3
- 229910052749 magnesium Inorganic materials 0.000 description 3
- 229910001425 magnesium ion Inorganic materials 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000002156 mixing Methods 0.000 description 3
- 235000021317 phosphate Nutrition 0.000 description 3
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 238000005086 pumping Methods 0.000 description 3
- 239000002002 slurry Substances 0.000 description 3
- 238000007711 solidification Methods 0.000 description 3
- 230000008023 solidification Effects 0.000 description 3
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 3
- 229920002554 vinyl polymer Polymers 0.000 description 3
- 229910052725 zinc Inorganic materials 0.000 description 3
- 239000011701 zinc Substances 0.000 description 3
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 2
- 229910000838 Al alloy Inorganic materials 0.000 description 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 2
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 2
- ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 description 2
- PTFCDOFLOPIGGS-UHFFFAOYSA-N Zinc dication Chemical compound [Zn+2] PTFCDOFLOPIGGS-UHFFFAOYSA-N 0.000 description 2
- 238000012644 addition polymerization Methods 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 229910052783 alkali metal Inorganic materials 0.000 description 2
- 239000011324 bead Substances 0.000 description 2
- 210000001124 body fluid Anatomy 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- 239000003518 caustics Substances 0.000 description 2
- 239000012459 cleaning agent Substances 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 239000000356 contaminant Substances 0.000 description 2
- 239000010949 copper Substances 0.000 description 2
- 229910052802 copper Inorganic materials 0.000 description 2
- 238000002425 crystallisation Methods 0.000 description 2
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- 238000009472 formulation Methods 0.000 description 2
- 238000007654 immersion Methods 0.000 description 2
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- 150000002632 lipids Chemical class 0.000 description 2
- 239000012263 liquid product Substances 0.000 description 2
- 239000000395 magnesium oxide Substances 0.000 description 2
- CPLXHLVBOLITMK-UHFFFAOYSA-N magnesium oxide Inorganic materials [Mg]=O CPLXHLVBOLITMK-UHFFFAOYSA-N 0.000 description 2
- AXZKOIWUVFPNLO-UHFFFAOYSA-N magnesium;oxygen(2-) Chemical compound [O-2].[Mg+2] AXZKOIWUVFPNLO-UHFFFAOYSA-N 0.000 description 2
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 description 2
- 238000012958 reprocessing Methods 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
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- 210000001179 synovial fluid Anatomy 0.000 description 2
- 229910052718 tin Inorganic materials 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- CIEZZGWIJBXOTE-UHFFFAOYSA-N 2-[bis(carboxymethyl)amino]propanoic acid Chemical compound OC(=O)C(C)N(CC(O)=O)CC(O)=O CIEZZGWIJBXOTE-UHFFFAOYSA-N 0.000 description 1
- 101100345345 Arabidopsis thaliana MGD1 gene Proteins 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical class OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 description 1
- 229910001369 Brass Inorganic materials 0.000 description 1
- 229910000906 Bronze Inorganic materials 0.000 description 1
- DBPRUZCKPFOVDV-UHFFFAOYSA-N Clorprenaline hydrochloride Chemical compound O.Cl.CC(C)NCC(O)C1=CC=CC=C1Cl DBPRUZCKPFOVDV-UHFFFAOYSA-N 0.000 description 1
- QXNVGIXVLWOKEQ-UHFFFAOYSA-N Disodium Chemical class [Na][Na] QXNVGIXVLWOKEQ-UHFFFAOYSA-N 0.000 description 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 description 1
- 239000005977 Ethylene Substances 0.000 description 1
- 229910000640 Fe alloy Inorganic materials 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical group C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- VQTUBCCKSQIDNK-UHFFFAOYSA-N Isobutene Chemical group CC(C)=C VQTUBCCKSQIDNK-UHFFFAOYSA-N 0.000 description 1
- JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical compound [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 description 1
- ZOKXTWBITQBERF-UHFFFAOYSA-N Molybdenum Chemical compound [Mo] ZOKXTWBITQBERF-UHFFFAOYSA-N 0.000 description 1
- 229920002266 Pluriol® Polymers 0.000 description 1
- 229920002845 Poly(methacrylic acid) Polymers 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 1
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 description 1
- QYKIQEUNHZKYBP-UHFFFAOYSA-N Vinyl ether Chemical class C=COC=C QYKIQEUNHZKYBP-UHFFFAOYSA-N 0.000 description 1
- 229910021536 Zeolite Inorganic materials 0.000 description 1
- 239000006096 absorbing agent Substances 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 229910000288 alkali metal carbonate Inorganic materials 0.000 description 1
- 150000008041 alkali metal carbonates Chemical class 0.000 description 1
- 229910052910 alkali metal silicate Inorganic materials 0.000 description 1
- 238000005904 alkaline hydrolysis reaction Methods 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 239000004599 antimicrobial Substances 0.000 description 1
- 239000002216 antistatic agent Substances 0.000 description 1
- 239000007844 bleaching agent Substances 0.000 description 1
- 239000010951 brass Substances 0.000 description 1
- 239000010974 bronze Substances 0.000 description 1
- 230000003139 buffering effect Effects 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 150000004649 carbonic acid derivatives Chemical class 0.000 description 1
- 239000003638 chemical reducing agent Substances 0.000 description 1
- 150000003841 chloride salts Chemical class 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 239000002872 contrast media Substances 0.000 description 1
- KUNSUQLRTQLHQQ-UHFFFAOYSA-N copper tin Chemical compound [Cu].[Sn] KUNSUQLRTQLHQQ-UHFFFAOYSA-N 0.000 description 1
- 239000002173 cutting fluid Substances 0.000 description 1
- 239000003599 detergent Substances 0.000 description 1
- ZBCBWPMODOFKDW-UHFFFAOYSA-N diethanolamine Chemical compound OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 description 1
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 description 1
- 238000002845 discoloration Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 239000000446 fuel Substances 0.000 description 1
- 239000000417 fungicide Substances 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 231100001261 hazardous Toxicity 0.000 description 1
- 150000002391 heterocyclic compounds Chemical group 0.000 description 1
- 229910052739 hydrogen Chemical group 0.000 description 1
- 239000001257 hydrogen Chemical group 0.000 description 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 1
- 230000003301 hydrolyzing effect Effects 0.000 description 1
- 239000003752 hydrotrope Substances 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- SYJRVVFAAIUVDH-UHFFFAOYSA-N ipa isopropanol Chemical compound CC(C)O.CC(C)O SYJRVVFAAIUVDH-UHFFFAOYSA-N 0.000 description 1
- 239000010410 layer Substances 0.000 description 1
- 239000010721 machine oil Substances 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- FPYJFEHAWHCUMM-UHFFFAOYSA-N maleic anhydride Chemical compound O=C1OC(=O)C=C1 FPYJFEHAWHCUMM-UHFFFAOYSA-N 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000011268 mixed slurry Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229910052750 molybdenum Inorganic materials 0.000 description 1
- 239000011733 molybdenum Substances 0.000 description 1
- 239000010705 motor oil Substances 0.000 description 1
- 229910052605 nesosilicate Inorganic materials 0.000 description 1
- 229910052759 nickel Inorganic materials 0.000 description 1
- 150000002823 nitrates Chemical class 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 150000004762 orthosilicates Chemical class 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000013618 particulate matter Substances 0.000 description 1
- 239000006072 paste Substances 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- LQPLDXQVILYOOL-UHFFFAOYSA-I pentasodium;2-[bis[2-[bis(carboxylatomethyl)amino]ethyl]amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC(=O)[O-])CCN(CC([O-])=O)CC([O-])=O LQPLDXQVILYOOL-UHFFFAOYSA-I 0.000 description 1
- 229920002239 polyacrylonitrile Polymers 0.000 description 1
- 229910000027 potassium carbonate Inorganic materials 0.000 description 1
- 235000019353 potassium silicate Nutrition 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- FQENQNTWSFEDLI-UHFFFAOYSA-J sodium diphosphate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OP([O-])([O-])=O FQENQNTWSFEDLI-UHFFFAOYSA-J 0.000 description 1
- 235000019795 sodium metasilicate Nutrition 0.000 description 1
- 239000001488 sodium phosphate Substances 0.000 description 1
- 229940048086 sodium pyrophosphate Drugs 0.000 description 1
- QUCDWLYKDRVKMI-UHFFFAOYSA-M sodium;3,4-dimethylbenzenesulfonate Chemical compound [Na+].CC1=CC=C(S([O-])(=O)=O)C=C1C QUCDWLYKDRVKMI-UHFFFAOYSA-M 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 150000003467 sulfuric acid derivatives Chemical class 0.000 description 1
- 239000002344 surface layer Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- RYCLIXPGLDDLTM-UHFFFAOYSA-J tetrapotassium;phosphonato phosphate Chemical compound [K+].[K+].[K+].[K+].[O-]P([O-])(=O)OP([O-])([O-])=O RYCLIXPGLDDLTM-UHFFFAOYSA-J 0.000 description 1
- 235000019818 tetrasodium diphosphate Nutrition 0.000 description 1
- 239000001577 tetrasodium phosphonato phosphate Substances 0.000 description 1
- 239000011135 tin Substances 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 150000003852 triazoles Chemical class 0.000 description 1
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
- 229910000406 trisodium phosphate Inorganic materials 0.000 description 1
- 235000019801 trisodium phosphate Nutrition 0.000 description 1
- OHOTVSOGTVKXEL-UHFFFAOYSA-K trisodium;2-[bis(carboxylatomethyl)amino]propanoate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)C(C)N(CC([O-])=O)CC([O-])=O OHOTVSOGTVKXEL-UHFFFAOYSA-K 0.000 description 1
- SOBHUZYZLFQYFK-UHFFFAOYSA-K trisodium;hydroxy-[[phosphonatomethyl(phosphonomethyl)amino]methyl]phosphinate Chemical class [Na+].[Na+].[Na+].OP(O)(=O)CN(CP(O)([O-])=O)CP([O-])([O-])=O SOBHUZYZLFQYFK-UHFFFAOYSA-K 0.000 description 1
- WFKWXMTUELFFGS-UHFFFAOYSA-N tungsten Chemical compound [W] WFKWXMTUELFFGS-UHFFFAOYSA-N 0.000 description 1
- 229910052721 tungsten Inorganic materials 0.000 description 1
- 239000010937 tungsten Substances 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 239000010457 zeolite Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/0005—Other compounding ingredients characterised by their effect
- C11D3/0073—Anticorrosion compositions
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/37—Polymers
- C11D3/3703—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
- C11D3/3707—Polyethers, e.g. polyalkyleneoxides
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
- C11D7/02—Inorganic compounds
- C11D7/04—Water-soluble compounds
- C11D7/06—Hydroxides
Definitions
- the invention relates to a mild alkaline solid cleaning composition, suitable for cleaning medical instruments, and methods for automated cleaning processing of surfaces with effective cleaning compositions.
- the invention relates to mild alkaline solid cleaning compositions useful in the cleaning of articles or surfaces, including plastic articles, plastic surfaces, metal articles, metal surfaces, such as surgical, medical, and dental instruments.
- Aqueous alkali cleaners are known as effective cleaning agents.
- many such alkali cleaners have disadvantages when used for automated cleaning processing due to the formation of foam, thus requires the content of additional foam inhibiting agents, which make the composition more complex.
- the formation of foam lowers the cleaning properties, due to the loss of mechanical agitation.
- pumping of foam dramatically reduce the liquid flow rates, thus causes dosing and transport problems in the sump, liquid conduits, as well as in the dispensing drawer. Thus, foam is not acceptable in an automated washer.
- alkaline sensitive metal such as, aluminum or aluminum containing alloys.
- Exemplary equipment having a surface containing an alkaline sensitive metals include surgical, medical, and dental instruments, sinks, cookware, utensils, machine parts, vehicles, tanker trucks, vehicle wheels, work surfaces, tanks, immersion vessels, spray washers, and ultrasonic baths.
- Aqueous alkali cleaners are known as effective cleaning agents.
- alkali cleaners have disadvantages when used on alkaline sensitive metals, such as, aluminum.
- a problem with using aqueous alkali systems to clean aluminum surfaces is the potential to corrode and/or discolor.
- the object of the present invention is to provide a mild alkaline solid cleaning composition, suitable for automated cleaning processing of hard and/or soft surfaces, such as metal and/or plastic surfaces, comprising:
- the weight-% ratio of the alkaline source to the polyethylene glycol is about > 30 : 1; and wherein the weight-% of the components are based on the total weight of the mild alkaline solid cleaning composition.
- the weight -% ratio of the alkaline source to the polyethylene glycol can be > 30 : 1 to > 3000 : 1, preferably about > 31 : 1 to > 300 : 1, further preferred about > 32 : 1 to > 100 : 1, and also preferred about > 32.5 : 1 to > 35 : 1.
- the mild alkaline solid cleaning composition suitable for automated cleaning processing of hard and/or soft surfaces, such as metal and/or plastic surfaces, comprising:
- weight-% of the components are based on the total weight of the mild alkaline solid cleaning composition.
- the mild alkaline solid cleaning composition of the invention is suitable for automated cleaning processing of hard and/or soft surfaces, such as metal and/or plastic surfaces, in particular metal instruments.
- the mild alkaline solid cleaning composition comprises a very low content of polyethylene glycol and an increased amount of at least one corrosion inhibitor that makes it extremely sensitive to metal articles, metal surfaces, plastic articles and/or plastic surfaces.
- the mild alkaline solid cleaning composition according to the invention may provide good cleaning performances even though the weight-% ratio of alkaline source to polyethylene glycol can be for example in the range from about > 30 : 1 to about ⁇ 3000 : 1, based on the total weight of the mild alkaline solid cleaning composition.
- the weigh-% ratio of alkaline source to polyethylene glycol can be in the range from about > 30 : 1 to about ⁇ 3000 : 1, preferably about > 31 : 1 to about ⁇ 300 : 1, further preferred about > 32 : 1 to about ⁇ 150 : 1, about > 32 : 1 to about ⁇ 100 : 1, about > 32 : 1 to about ⁇ 50 : 1, and also preferred about > 32.5 : 1 to about ⁇ 35 : 1, wherein the weight-% of the components are based on the total weight of the mild alkaline solid cleaning composition.
- alkaline sensitive metal identifies those metals that exhibit corrosion and/or discoloration when exposed to an aqueous alkaline solution.
- An aqueous alkaline solution is an aqueous solution having a pH that is greater than about 8.
- Exemplary alkaline sensitive metals include soft metals such as aluminum, nickel, tin, zinc,/copper, brass, bronze, and mixtures thereof.
- Aluminum and aluminum alloys are common alkaline sensitive metals that can be cleaned by the cleaning mild alkaline solid cleaning compositions.
- references herein to a "solid" composition are to those, which are solid at about 15° C and up to about 60° C.
- the mild alkaline solid cleaning composition of the present invention may be at about 15° C and up to about 60° C form stable and/or rigid.
- a solvent, preferably water, can be added add. 100 wt.-% to the mild alkaline solid cleaning composition of the invention.
- the solvent content, such as the water content, of the mild alkaline solid cleaning composition according to the invention is simply determined by subtracting the amounts of all the usual components from 100 wt. %.
- the weight-% (wt.-%) of the components are calculated based on the total weight amount of the mild alkaline solid cleaning composition, if not otherwise stated.
- the ratio of components of the mild alkaline solid cleaning composition is parts by weight, if not otherwise stated.
- the total amount of all components of the mild alkaline solid cleaning composition does not exceed 100 wt.-%.
- the mild alkaline solid cleaning compositions are free of other surfactants, except polyethylene glycol.
- mild alkaline solid cleaning compositions can be free of a hydrotrope component.
- mild alkaline solid cleaning compositions can be free of a zeolite, except sodium disilicate.
- the mild alkaline solid cleaning compositions can be free of at least one additive, preferably all additives, selected from the group of antimicrobials, fungicides, fragrances, dyes, antistatic agents, UV absorbers, reducing agents and/or buffering compounds.
- the ratio or concentration of polyethylene glycol in the mild alkaline solid cleaning composition of the present invention is selected to high.
- reducing the amount of polyethylene glycol to a very low content leads to an improper cleaning result. It has been surprisingly found that the insufficient cleaning characteristics due to the very low content of polyethylene glycol can be compensated and improved by increasing the amount of corrosion inhibitor.
- the increased amount of corrosion inhibitor has a synergetic cleaning effect that allows to reduce the polyethylene glycol content.
- the decrease content of polyethylene glycol reduces unwanted foam generation including the formation of micro bubbles to an absolute minimum, which improves disinfection of the surfaces to be cleaned.
- the specific ratio of the at least one corrosion inhibitor to polyethylene glycol according to the present invention provides a good cleaning effect in combination with no visible foaming as required for an automated processing of metal articles, metal surfaces, plastic articles and/or plastic surfaces.
- a mild alkaline solid cleaning composition of the present invention used in an automated washing process is surprisingly good, although the concentration of the polyethylene glycol in the mild alkaline solid cleaning composition of the present invention is extremely low due to the addition of an increased amount of at least one corrosion inhibitor.
- An aqueous alkaline composition having a high pH are often more corrosive than an aqueous composition having a light acidic pH.
- the concentrated liquid composition of the invention can have a pH in the range of about > 12.5 pH to about ⁇ 13.5 pH.
- the pH of the ready-to-use aqueous alkaline solutions can be adjusted to a lower pH in the range of about > 9.5 pH to about ⁇ 11 pH.
- the soil removal or cleaning action of an aqueous solution of the mild alkaline solid cleaning composition according to the present invention can be improved by adding at least one sequestering agent to the mild alkaline solid cleaning composition, preferably at least one sequestering agent that exhibits soil removal properties.
- the source of alkalinity can be any source of alkalinity that is compatible with the other components of the cleaning composition and that will provide the use solution, i.e. concentrated liquid composition as well as the ready-to-use liquid mild alkaline cleaning solution with the desired pH.
- Exemplary sources of alkalinity include alkali metal hydroxides, alkali metal salts, phosphates, amines, and mixtures thereof.
- Exemplary alkali metal hydroxides include sodium hydroxide, potassium hydroxide, and lithium hydroxide.
- Exemplary alkali metal salts include sodium carbonate, trisodium phosphate, potassium carbonate, and mixtures thereof.
- Exemplary phosphates include sodium pyrophosphate, potassium pyrophosphate, and mixtures thereof.
- Exemplary amines include alkanolamine selected from the group comprising triethanolamine, monoethanolamine, diethanolamine, and mixtures thereof.
- the source of alkalinity preferably an alkali metal hydroxide
- Alkali metal hydroxides are commercially available as pellets or beads having a mix of particle sizes ranging from 12-100 U. S. mesh, or as an aqueous solution, as for example, as about 45 wt. %, about 50 wt. % and about 73 wt. % solution.
- the mild alkaline solid cleaning composition may comprises about > 10 wt.-% to about ⁇ 35 wt.-%, preferably about > 13 wt.-% to about ⁇ 24 wt.-%, and more preferred about > 15 wt.-% to about ⁇ 20 wt.-%, of at least one alkaline source, preferably sodium hydroxide; wherein the weight-% of the components are based on the total weight of the mild alkaline solid cleaning composition.
- a suitable polyethylene glycol for use in the present invention can have an average mol weight (MW) in the range of about > 4000 to about ⁇ 12000, preferably about > 6000 to about ⁇ 10000 and more preferred of about > 7000 to about ⁇ 8000.
- Polyethylene glycol that can be used are marketed for example by BASF under the tradename PLURIOL ® .
- the mild alkaline solid cleaning composition may comprise about > 0.1 wt.-% to about ⁇ 1 wt.-%, preferably about > 0.2 wt.-% to about ⁇ 0.8 wt.-%, further preferred about > 0.3 wt.-% to about ⁇ 0.7 wt.-%, and more preferred about > 0.4 wt.-% to about ⁇ 0.6 wt.-%, and most preferred about 0.5 wt.-%, of at least one polyethylene glycol, preferably a polyethylene glycol with an average mol weight in the range of 4.000 to 12.000, and more preferred a polyethylene glycol having an average mol weight of about 8,000; wherein the weight-% of the components are based on the total weight of the mild alkaline solid cleaning composition.
- At least one corrosion inhibitor preferably at least two corrosion inhibitors, in large amounts, are used to compensate the extreme low polyethylene glycol content of the composition in order to reach an excellent cleaning performance as well as to prevent the corrosion of an article to be cleaned.
- silicate(s) corrosion inhibitor and more preferred a disilicate corrosion inhibitor can be used in the solid composition according to the present invention.
- the silicate(s) and/or disilicate corrosion inhibitor can be an alkali silicate and/or alkali disilicate.
- inhibitors that can be used can be selected from the group comprising calcium acetate, calcium chloride, calcium gluconate, calcium phosphate, calcium borate, calcium carbonate, calcium citrate, calcium lactate, calcium sulfate, calcium tartrate, benzotriazole, 1,2,3-benzotriazole and mixtures thereof.
- the corrosion inhibitor is a heterocyclic compound, a triazole derivate, such as a benzotriazole or 1,2,3-benzotriazole and mixtures thereof.
- silicates include sodium metasilicates, sesquisilicates, orthosilicates, potassium silicates, and mixtures thereof. However, most preferred can be sodium silicate.
- the silicates may comprise at least one crystalline layer-forming silicate of the general formula NaMSix02x+l .yH20, wherein M represents sodium or hydrogen, x is a number from about 1.9 to about 22, preferably about 1.9 to about 4 and y stands for a number from about 0 to about 33.
- the crystalline layer- forming silicates of the formula NaMSix022x+l .yH20 are marketed for example by Clariant GmbH (Germany) under the trade names Na-S S, eg. Na-S S-1 (Na2Si22045.xH20, Kenyait), Na-S S-2 (Na2Sil4029.xH20, Magadiit), Na- SKS-3 (Na2Si8017.xH20) or Na-SKS-4 ( a2Si409.xH20, Makatit). Crystalline, layered silicates of the above formula, in which x stands for 2, are particularly suitable for the purposes of the present invention.
- Na-SKS-5 alpha -Na2Si205
- Na-SKS-7 beta -Na2Si205, Natrosilit
- Na-SKS-9 NaHSi205.H20
- Na-SKS-10 NaHSi205.3H20, Kanemit
- Na-SKS-11 t-Na2Si205
- Na-SKS-13 NaHSi205
- Na-SKS-6 delta -Na2Si205
- silicates can comprise a content by weight of crystalline layered silicates of formula NaMSix02x+l.yH20 of 0.1 to 20 wt. %, preferably about 0.2 to about 15 wt. % and particularly about 0.4 to about 10 wt. %, each based on the total weight of the corrosion inhibitor agent.
- corrosion inhibitors can be suitable added to the mild alkaline solid cleaning composition of this invention include magnesium and/or zinc ions and Ca (N0 2 ) 2 .
- the metal ions are provided in water-soluble form.
- Examples of useful water-soluble forms of magnesium and zinc ions are the water- soluble salts thereof including the chlorides, nitrates and sulfates of the respective metals. If any of the alkalinity providing agents are the alkali metal carbonates, bicarbonates or mixtures of such agents, magnesium oxide can be used to provide the Mg ion.
- the magnesium oxide is water soluble and is a preferred source of Mg ions.
- the useful carboxylated polymer corrosion inhibitors may be generically categorized as water-soluble carboxylic acid polymers such as polyacrylic and polymethacrylic acids or vinyl addition polymers, in addition to the acid-substituted polymers used in the present invention.
- water-soluble carboxylic acid polymers such as polyacrylic and polymethacrylic acids or vinyl addition polymers, in addition to the acid-substituted polymers used in the present invention.
- vinyl addition polymer corrosion inhibitors contemplated maleic anhydride copolymers as with vinyl acetate, styrene, ethylene, isobutylene, acrylic acid and vinyl ethers are examples.
- the polymers tend to be water-soluble or at least colloidally dispersible in water.
- the molecular weight of these polymers may vary over a broad range although it is preferred to use polymers having average molecular weights ranging between about 1,000 up to about 1,000, 000. These polymers have a molecular weight of about 100,000 or less and between about 1,000 and about 10,000.
- the polymers or copolymers may be prepared by either addition or hydrolytic techniques.
- maleic anhydride copolymers are prepared by the addition polymerization of maleic anhydride and another comonomer such as styrene.
- the low molecular weight acrylic acid polymer corrosion inhibitors may be prepared by addition polymerization of acrylic acid or its salts either with itself or other vinyl comonomers.
- such polymers may be prepared by the alkaline hydrolysis of low molecular weight acrylonitrile homopolymers or copolymers.
- the corrosion inhibitor can be used in quantities of about > 0 to about ⁇ 10, preferably about > 0.05 to about ⁇ 5, also preferred about > 0.1 to about ⁇ 3 and more preferred of about > 0.5 to about ⁇ 2; wherein the weight-% of the components are based on the total weight of the composition.
- the mild alkaline solid cleaning composition may comprises about > 15 wt.-% to about ⁇ 40 wt.-%, preferably about > 18 wt.-% to about ⁇ 35 wt.-%, further preferred about > 20 wt.-% to about ⁇ 28 wt.-%, and more preferred about > 23 wt.-% to about ⁇ 25 wt.-%, of at least one corrosion inhibitor, preferably sodium disilicate, and more preferred at least two corrosion inhibitors, preferably a benzotriazol and sodium disilicate and most preferred 1,2,3-benzotriazole and sodium disilicate; wherein the weight-% of the components are based on the total weight of the mild alkaline solid cleaning composition.
- the mild alkaline solid cleaning composition according to the present invention can comprise at least one threshold inhibitor/crystal modifier.
- the threshold inhibitor/crystal modifier can be selected from the group comprising salts of phosphonocarboxylic acids, phosphonates, salts of 1-hydroxyethylidene -1,1,- diphosphonic acid (HEDP), salts of acid substituted polymers, and mixtures thereof, preferably salts of acid substituted polymers of monomers of acrylate, methacrylate, salts of polyitaconic acid, salts of polymaleic acid, and mixtures thereof.
- salts of polyacrylic acid are particularly preferred.
- the amount of threshold inhibitor/crystal modifier can be about > 0.5 wt.-% to about ⁇ 15 wt.-%, preferably about > 1 wt.-% to about ⁇ 10 wt.-%, and more preferred about > 3 wt- % to about ⁇ 5 wt.-% of at least one threshold inhibitor/crystal modifier, preferably the threshold inhibitor/crystal modifier is a salt of a polyacrylic acid; wherein the weight-% of the components are based on the total weight of the mild alkaline solid cleaning composition.
- the mild alkaline solid cleaning composition according to the present invention can comprise at least one sequestering agent.
- the sequestering agent can be selected from the group of sodium gluconate, pentasodium salt of diethylenetriamine pentaacetic acid, sodium glucoheptonate, salts of ethylene diamine tetraacetic acid, salts of ethylene diamine tetraacetic acid, salts of hydroxyethyl ethylene diamine triacetic acid, salts of hydroxyethyl ethylene diamine triacetic acid, salts of nitrilotriacetic acid, salts of nitrilotriacetic acid, diethanolglycine sodium salt, ethanoldiglycine disodium salt, salts of hydroxymonocarboxylic acid compounds, salts of hydroxydicarboxylic acid compounds, salts of amine containing carboxylic acids, tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate (GDLA) and mixtures thereof.
- GDLA tetrasodium N,N-bis(carboxyla
- At least one sequestering agent that exhibits soil removal properties when used at a pH of at least about 10.0.
- the sequestering agent is provided for tying up metals in the soil to assist in cleaning and detergency.
- the sequestering agent can be provided as part of the mild alkaline solid cleaning composition.
- Exemplary sequestering agents that exhibit soil removal properties at a pH of greater than about 10.0 that can be used according to the invention include sodium gluconate, pentasodium salt of diethylenetriamine pentaacetic acid (available under the name Versenex 80), sodium glucoheptonate, ethylene diamine tetraacetic acid (EDTA), salts of ethylene diamine tetraacetic acid, hydroxyethyl ethylene diamine triacetic acid (HEDTA), salts of hydroxyethyl ethylene diamine triacetic acid, nitrilotriacetic acid (NTA), salts of nitrilotriacetic acid, diethanolglycine sodium salt (DEG), ethanoldiglycine disodium salt (EDG), tetrasodium N,N-bis(carboxylatomethyl)-L- glutamate (GLDA), methyl glycine diacetic acid (MGDA)and mixtures thereof.
- EDTA ethylene diamine tetra
- Exemplary salts of ethylene diamine tetraacetic acid include disodium salts, tetrasodium salts, diammonium salts, and trisodium salts.
- An exemplary salt of hydroxy ethyl ethylene diamine triacetic acid is the trisodium salt.
- the sequestering agent can include mixtures of different sequestering agents.
- the amount of sequestering agent can be about > 5 wt.-% to about ⁇ 40 wt.-%, preferably about > 15 wt.-% to about ⁇ 30 wt.-%, and more preferred about > 20 wt.-% to about ⁇ 25 wt.-% of at least one sequestering agent, preferably the sequestering agent is a salt of an amine containing carboxylic acid, and more preferred terasodium N,N- bis(carboxylatomethyl)-L-glutamate (GLDA); wherein the weight-% of the components are based on the total weight of the mild alkaline solid cleaning composition.
- the sequestering agent is a salt of an amine containing carboxylic acid, and more preferred terasodium N,N- bis(carboxylatomethyl)-L-glutamate (GLDA); wherein the weight-% of the components are based on the total weight of the mild alkaline solid cleaning composition.
- Suitable solvents include, but are not limited to, water, alcohols, glycols, glycol ethers, esters, and the like, or combinations thereof.
- Suitable alcohols include, but are not limited to, ethanol, isopropanol (propan-2-ol), 2-butoxy ethanol (butyl glycol), 1-decanol, benzyl alcohol, glycerin, monoethanolamine (MEA), and the like, or combinations thereof.
- Suitable glycols include, but are not limited to, ethylene glycol (monoethylene glycol or MEG), diethylene glycol (propylene glycol or butoxy diglycol or DEG), triethylene glycol (TEG), tetraethylene glycol (TETRA EG), glycerin, propylene glycol, dipropylene glycol, hexylene glycol, and the like, or combinations thereof.
- MEG monoethylene glycol
- DEG diethylene glycol
- TEG triethylene glycol
- TETRA EG tetraethylene glycol
- glycerin propylene glycol, dipropylene glycol, hexylene glycol, and the like, or combinations thereof.
- the composition comprises at least two solvents and more preferred the composition comprises water and hexylene glycol.
- the amount of an additional solvent that is not water, preferably hexylene glycol can be about > 0.1 wt.-% to about ⁇ 5 wt.-%, preferably about > 0.4 wt.-% to about ⁇ 1 wt.-%, and more preferred about > 0.6 wt.-% to about ⁇ 0.8 wt.-%; wherein the weight-% of the components are based on the total weight of the mild alkaline solid cleaning composition.
- Water can be added add 100 wt.-%; wherein the weight-% of the components are based on the total weight of the mild alkaline solid cleaning composition.
- the mild alkaline solid cleaning composition may comprise: - about > 10 wt.-% to about ⁇ 35 wt.-%, preferably about > 13 wt.-% to about ⁇ 24 wt.-%, and more preferred about > 15 wt.-% to about ⁇ 20 wt.-%, of at least one alkaline source, preferably sodium hydroxide;
- a solvent preferably water, is added add. 100 wt.-%;
- the weight-% of the components are based on the total weight of the of the mild alkaline solid cleaning composition.
- the mild alkaline solid cleaning composition may comprise:
- At least one corrosion inhibitor preferably sodium disilicate, and more preferred at least two corrosion inhibitors, preferably a benzotriazol and sodium disilicate; - about > 0.5 wt.-% to about ⁇ 15 wt.-%, preferably about > 1 wt.-% to about ⁇ 10 wt.-%, and more preferred about > 3 wt.-% to about ⁇ 5 wt.-% of at least one threshold inhibitor/crystal modifier, preferably the threshold inhibitor/crystal modifier is a salt of a polyacrylic acid;
- the sequestering agent is a salt of an amine containing carboxylic acid, and more preferred terasodium N,N-bis(carboxylatomethyl)-L-glutamate (GLDA);
- a solvent preferably water, is added add. 100 wt.-%;
- the weight-% of the components are based on the total weight of the of the mild alkaline solid cleaning composition.
- Another object of the present invention is directed to a liquid mild alkaline cleaning composition obtained from the mild alkaline solid cleaning composition of the invention.
- the cleaning compositions according to the invention can take the form of a single concentrate or multiple concentrates that can be diluted and combined to provide a ready-to-use liquid mild alkaline cleaning solution.
- the ready-to-use liquid mild alkaline cleaning solution can be directly used to clean articles and need not to be diluted.
- the ready-to-use liquid composition according to the invention may be used to clean articles having a metal surface, such as surgical, medical, and dental instruments, including endoscopes.
- the solution can be in the form of a concentrate that can be diluted with a solvent, such as water, to provide a ready-to-use liquid mild alkaline cleaning solution that can be used for cleaning applied to articles having a metal surface, such as surgical, medical, and dental instruments.
- a solvent such as water
- the solutions can be provided as a relatively dilute solution that can be, without the addition of water, to provide an organic ready-to use solution, for example an alcohol based ready-to use solution, that can be for cleaning applied to articles having a metal surface, such as surgical, medical, and dental instruments.
- an organic ready-to use solution for example an alcohol based ready-to use solution, that can be for cleaning applied to articles having a metal surface, such as surgical, medical, and dental instruments.
- the concentrate liquid composition and/or the ready-to-use liquid mild alkaline cleaning solution can be used in an automated washing process for cleaning and disinfection metal and plastic surfaces, in particular metal surfaces of surgical, medical, and dental instruments including endoscopes, from body fluids, such as blood, lipids, contrast agent and synovial fluids from joints adhere to the metal surface used during a procedure.
- the source of alkalinity and addition of the solvent, preferably water, are provided so that the concentrated, preferably aqueous, liquid composition of the mild alkaline solid cleaning composition according to the present invention may have a pH in the range of about 12 pH to about 14 pH, preferably a pH in the range of about 12.5 pH to about 13.5 pH and more preferred a pH of about 13 pH.
- the ratio of the solvent, preferably water, to solid, to provide a concentrated liquid composition, preferably an aqueous solution, of the mild alkaline solid cleaning composition can be in the range of from about 200 : 1 to about 10 : 1, preferably about 100 : 1 to about 12 : 1, further preferred about 50 : 1 to about 15 : 1, also preferred about 40 : 1 to about 17 : 1 and in particular preferred about 30 : 1 to 20 : 1.
- the alkaline concentrated liquid composition can comprise:
- a solvent preferably water, is added add. 100 wt.-%; wherein the weight-% of the components are based on the total weight of the alkaline concentrated liquid composition.
- the mild alkaline solid cleaning composition can comprise:
- the threshold inhibitor/crystal modifier is a salt of a polyacrylic acid
- the sequestering agent is a salt of an amine containing carboxylic acid, and more preferred terasodium N,N-bis(carboxylatomethyl)-L-glutamate (GLDA);
- a solvent preferably water, is added add. 100 wt.-%;
- the weight-% of the components are based on the total weight of the alkaline concentrated liquid composition.
- the source of alkalinity and addition of solvent, preferably water, are provided so that the aqueous ready-to-use liquid mild alkaline cleaning solution according to the present invention may have a pH in the range of about > 9.5 pH to about ⁇ 11.5 pH and preferably a pH in the range of about > 10.0 pH to about ⁇ 11 pH.
- the ratio of the solvent, preferably water, to solid, to provide a ready-to-use liquid mild alkaline cleaning solution, preferably an aqueous solution, of the mild alkaline solid cleaning composition can be in the range of from about 60,000 : 1 to about 100 : 1, preferably about 30,000 : 1 to about 300 : 1, further preferred about 10,000 : 1 to about 500 : 1, also preferred about 5,000 : 1 to about 750 : 1 and in particular preferred about 2,500 : 1 to about 1,000 : 1.
- the ready-to-use liquid mild alkaline cleaning solution can comprise:
- a solvent preferably water, is added add. 100 wt.-%;
- the weight-% of the components are based on the total weight of the ready-to-use liquid mild alkaline cleaning solution.
- the ready-to-use liquid mild alkaline cleaning solution can comprise:
- the threshold inhibitor/crystal modifier is a salt of a polyacrylic acid
- the sequestering agent is a salt of an amine containing carboxylic acid, and more preferred terasodium N,N-bis(carboxylatomethyl)-L-glutamate (GLDA);
- a solvent preferably water, is added add. 100 wt.-%;
- the weight-% of the components are based on the total weight of the ready-to-use liquid mild alkaline cleaning solution.
- all components of the mild alkaline solid cleaning composition can be mixed together or added portionwise or one after the other.
- a cast process then solidifies the heated slurry, e.g. the solidification can erupt after cooling down a NaOH melt by crystallization.
- Another object of the invention is directed to a cleaning apparatus.
- the cleaning apparatus is used to clean and to disinfect articles having a metal surface, such as surgical, medical, and dental instruments.
- the cleaning apparatus includes at least a first tank to receive the mild alkaline solid cleaning composition of the invention; at least a second component tank to receive water diluted concentrated composition or a ready-to-use liquid mild alkaline cleaning solution of said mild alkaline solid cleaning composition of the invention, a water feed, and a use solution line; and optional a third component tank to receive a day portion of the concentrated composition or a ready-to-use liquid mild alkaline cleaning solution of the invention.
- the first component tank is provided for containing the mild alkaline solid cleaning composition of the invention.
- the first component tank can be provided for mixing water to the mild alkaline solid cleaning composition to provide a concentrated liquid composition.
- the mild alkaline solid cleaning composition can be mixed with water in a circulation method to obtain a defined alkaline aqueous concentrated liquid composition.
- the second component tank is provided for receiving the aqueous concentrated liquid composition or for mixing water to the alkaline aqueous concentrated liquid composition to provide a ready-to-use liquid mild alkaline cleaning solution.
- the optional third component tank is provided for receiving a day portion of the aqueous concentrated liquid composition or for mixing water to the alkaline aqueous concentrated liquid composition to provide a day portion of a ready-to-use liquid mild alkaline cleaning solution.
- the water feed is provided for conveying water to the first tank, second tank (makeup tank) and/or third tank (day tank) for dissolving the mild alkaline solid cleaning composition (first tank) and/or for providing an aqueous concentrated alkaline liquid composition or a ready-to-use liquid mild alkaline cleaning solution (second tank) and/or for providing an aqueous ready-to-use liquid mild alkaline cleaning solution (third tank).
- first tank the aqueous concentrated alkaline liquid composition
- second tank ready-to-use liquid mild alkaline cleaning solution
- third tank aqueous ready-to-use liquid mild alkaline cleaning solution
- the aqueous concentrated alkaline liquid composition is transferred to the day tank, by the time the defined concentration, pH, volume and/or temperature is reached.
- the makeup tank (second tank) and more preferred the third tank (day tank) can be used to receive and stock the alkaline aqueous concentrated liquid composition or the ready-to-use liquid mild alkaline cleaning solution.
- Most preferred is to provide the ready-to- use liquid mild alkaline cleaning solution at the place of use, for example in an applicator, by adding sufficient water.
- the aqueous concentrated alkaline liquid composition can be conveyed from the second tank or a day tank (optional third tank) to a dispenser and the dispenser sprays out the ready-to-use liquid mild alkaline cleaning solution at the place of operation in a defined concentration.
- the solution line is provided for conveying solution from the second container to a use solution applicator.
- the mild alkaline solid cleaning composition of the invention can be used in combination with a healthcare solid dispenser.
- This dispenser sprays out the mild alkaline solid cleaning composition of the invention having the form of a capsule in a circulation method to a defined concentration.
- This alkaline aqueous concentrated liquid composition is collected in a makeup tank and transferred to a day tank as soon as the concentration and referring conductivity has reached the defined level. From there the pumps of the washer disinfectors dose the cleaning alkaline aqueous concentrated liquid composition in the cleaning cycle of the reprocessing step.
- the solid can be diluted to a 5% alkaline aqueous concentrated liquid composition in the dispenser.
- the ready-to-use liquid mild alkaline cleaning solution or the concentrated liquid composition can be in any form including liquid, gel, paste and slurry.
- the cleaning solutions i.e. ready-to-use liquid mild alkaline cleaning solution and/or the concentrated liquid composition, are suitable to treat any metal surface contaminated with a wide variety of contaminants.
- Exemplary contaminants include body fluids, such as blood, lipids and synovial fluids and chemical residues.
- aqueous cleaning solutions of this invention i.e. the aqueous alkaline ready-to-use liquid mild alkaline cleaning solution and/or the concentrated aqueous alkaline liquid composition, may be used at any temperature, including an elevated temperature of from about 30° C to about 70° C, preferably about 45° C to about 60° C and more preferred about 55° C. After contact with the cleaning solution, the solution is removed from the metal or plastic surface.
- the contact time of the aqueous cleaning solution in an automated process, i.e. ready- to-use liquid mild alkaline cleaning solution and/or the concentrated liquid composition, with the metal substrates will vary depending upon the degree of contamination but broadly will range between a few seconds or about > 1 minute to about ⁇ 30 minutes, with about > 3 minutes to about ⁇ 15 minutes being more typical and most preferred is about > 5 minutes to about ⁇ 10 minutes.
- a first container comprising an alkaline solid composition according to claims 1 to 10;
- a second container comprising a concentrated liquid composition of the solid composition according to claim 12 or 14 having a pH of about > 12.5 to about ⁇ 13.5, preferably a pH of about 13;
- composition or a ready to use solution having a pH of about > 9.5 to about ⁇ 11.0;
- a use solution line for conveying the use solution from the second container and/or third container to a use solution applicator and/or to the place of use.
- the composition of the invention has a surprising cleaning efficacy due to none foam formation, if mixed with water, as sump solution or in the dispensing drawer.
- Metal surfaces and/or plastic surfaces in need of cleaning are found in several locations. Exemplary locations include surgical instruments, medical instruments, and dental instruments, sinks, cookware, utensils, machine parts, vehicles, tanker trucks, vehicle wheels, work surfaces, tanks, immersion vessels, spray washers, and ultrasonic baths.
- the cleaning compositions of the present invention can be used for removing residues including blood, greases, cutting fluids, drawing fluids, machine oils, antirust oils such as cosmoline, carbonaceous soils, sebaceous soils, particulate matter, waxes, paraffins, used motor oil, fuels, etc..
- Metal surfaces that can be cleaned include iron-based metals such as iron, iron alloys, e. g. steel, tin, aluminum, copper, tungsten, titanium, molybdenum, etc., for example.
- the structure of the metal surface to be cleaned can vary widely.
- the metal surface and/or plastic surface can be as a metal and/or plastic part of complex configuration, sheeting, coils, rolls, bars, rods, plates, disks, etc..
- liquid alkaline cleaning solution of the invention in particular the ready-to-use-solution to clean metal and/or plastic articles, especially metal instruments, plastic instruments, instruments with a plastic surface and/or instruments with a metal surface.
- liquid alkaline cleaning solution of the invention in particular the ready-to-use-solution, to clean in an automated instrument processing metal and/or plastic articles, especially metal instruments, plastic instruments, instruments with a plastic surface and/or instruments with a metal surface.
- alkaline concentrates were provided in a solid form:
- This test method provides a basis to assess the foam formation properties of the liquid alkaline cleaning composition of the invention.
- An aqueous ready-to-use liquid mild alkaline cleaning solution is formed, wherein 1.0 g of examples El to E7 are dissolved in 100 ml of deionized water each.
- the long-necked glass cylinder was then turned up and down 20 x times in 20 seconds. Thereafter the glass cylinder was placed and the foam depth of each cylinder was scaled in ml to determine the foam formation. This test was carried out at a temperature of the cleaning solution at ambient temperature, 20° C and 55° C. The foam height are given in ml.
- the table 2 shows the result of the foam formation caused by the aqueous ready-to-use liquid mild alkaline cleaning solution of examples El to E7 obtained by the foam formation test.
- This test method provides a basis to assess the enhanced metal-surface-safeness of the liquid alkaline cleaning composition of the invention with respect to corrosion.
- the cleaning compositions El to E7 and comparative compositions VI to V14 were diluted with deionized water to a 0.8 wt.-% ready-to-use liquid mild alkaline cleaning solution.
- the weights of aluminum test plates of 100 mm x 50 mm x 1.5 mm were recorded and then placed in the center area of the bottom of a 350 ml wide-necked screw cap flask each. The aluminum test plates were completely submerged. Subsequently, each wide-necked screw cap flask was filed to the top with said 0.8 wt.-% ready-to-use liquid mild alkaline cleaning solution El to E7 and VI to V14 having a temperature of 23° C.
- the wide-necked screw cap flasks were closed with the cap and allow staying for 7 days at a temperature of 23° C. Thereafter, the aluminum test plates were removed, rinsed with deionized water, placed on a clean paper towel and allowed to dry at a temperature of 23° C. The aluminum test plates were then weighted and the weight was taken to the fourth place. Subsequently the aluminum test plates were returned in there wide-necked screw cap flasks for another 7 days. Thereafter, the aluminum test plates were removed, rinsed with deionized water, placed on a clean paper towel and allowed to dry at a temperature of 23° C. The aluminum test plates were then weighted and the weight was taken to the fourth place.
- N,N- 25 22 22 bis(carboxylatomethyl)-L- glutamate (GLDA)
- aqueous ready-to-use liquid mild alkaline cleaning solution is formed, wherein 1.0 g of examples El to E7 and VI to V14 are dissolved in 100 ml of deionized water each.
- compositions El to E7 compared to VI to V14 were tested in an automatic metal instrument cleaning apparatus Miele G 7836 CD, Program DES- VAR-TD, 55 °C, 10 minutes.
- the term “about” refers to variation in the numerical quantity that can occur, for example, through typical measuring and liquid handling procedures used for making concentrates or use solutions in the real world; through inadvertent error in these procedures; through differences in the manufacture, source, or purity of the ingredients used to make the compositions or carry out the methods; and the like.
- the term “about” also encompasses amounts that differ due to different equilibrium conditions for a composition resulting from a particular initial mixture. Whether or not modified by the term “about”, the claims include equivalents to the quantities.
- composition containing "a compound” includes a mixture of two or more compounds.
- the term “or” is generally employed in its sense including “and/or” unless the content clearly dictates otherwise.
Abstract
The invention relates to a mild alkaline solid cleaning composition suitable for cleaning metal surfaces, a solution thereof and methods for automated cleaning processing of surfaces with effective cleaning compositions. The mild alkaline solid cleaning composition for cleaning metal surfaces, comprising: - about ≥ 10wt.-% of at least one alkaline source, - about ≥ 0.1 of at least one polyethylene glycol, and - about ≥ 20 wt.-% of at least one corrosion inhibitor; wherein the weight-% ratio of the alkaline source to the polyethylene glycol is > 30: 1, and the components are based on the total weight of the mild alkaline solid cleaning composition.
Description
MILD ALKALINE SOLID INSTRUMENT CLEANER
Description
Field of the Invention
The invention relates to a mild alkaline solid cleaning composition, suitable for cleaning medical instruments, and methods for automated cleaning processing of surfaces with effective cleaning compositions. In particular, the invention relates to mild alkaline solid cleaning compositions useful in the cleaning of articles or surfaces, including plastic articles, plastic surfaces, metal articles, metal surfaces, such as surgical, medical, and dental instruments.
Background of the Invention
Many commercial and domestic articles include surface metal layers. Such articles are known to those skilled in a variety of occupations or domestic activities, particularly those working in industrial plants, hospitals, maintenance and repair services, manufacturing facilities, kitchens, restaurants and the like. Surgical, medical, and dental instruments after use are typically contaminated with blood and other body matter and potentially with infectious microorganisms. Before being reused in a future procedure these instruments must be washed and disinfected where indicated.
Aqueous alkali cleaners are known as effective cleaning agents. However, many such alkali cleaners have disadvantages when used for automated cleaning processing due to the formation of foam, thus requires the content of additional foam inhibiting agents, which make the composition more complex. The formation of foam lowers the cleaning properties, due to the loss of mechanical agitation. Further, pumping of foam dramatically reduce the liquid flow rates, thus causes dosing and transport problems in the sump, liquid conduits, as well as in the dispensing drawer. Thus, foam is not acceptable in an automated washer.
Many articles having a surface that requires cleaning contain an alkaline sensitive metal, such as, aluminum or aluminum containing alloys. Exemplary equipment having a surface containing an alkaline sensitive metals include surgical, medical, and dental instruments, sinks, cookware, utensils, machine parts, vehicles, tanker trucks, vehicle wheels, work surfaces, tanks, immersion vessels, spray washers, and ultrasonic baths. Aqueous alkali cleaners are known as effective cleaning agents. However, many alkali cleaners have disadvantages when used on alkaline sensitive metals, such as, aluminum. A problem with
using aqueous alkali systems to clean aluminum surfaces is the potential to corrode and/or discolor.
One particular disadvantage of known commercial concentrated liquid products such as surface cleaners, detergent bleach, automatic instrument and cleaning formulations and the like comprising caustic alkali are hazardous, causes chemical "burns" if splashed onto the skin and causes corrosion of sensitive metal surfaces that come into contact with aqueous alkaline solutions. Further, the known commercial instrument processing liquid concentrated caustic alkali solutions have the disadvantage of transportation and storage because they are bulky. Although said commercial liquid products have an excellent disinfection effects the danger for humans and environment is still considerable, since the commercial products are liquid.
It is still a need in prior art to provide a mild alkaline solid cleaning composition for automated cleaning processing of hard and/or soft surfaces. In particular, it is a need to provide a mild alkaline solid cleaning composition for automated cleaning processing of metal surface layers to remove blood or other matter are allowed to dry, which is not bulky, avoids the disadvantages of transport and storage of liquids, provides a rapid dissolution in water, and develops after dissolution based on a low active concentration a good cleaning effect. Further, it shows no foam formation during the automated processing and prevents corrosion of metal surfaces that are exposed to aqueous alkaline solutions.
Summary of the Invention
The object of the present invention is to provide a mild alkaline solid cleaning composition, suitable for automated cleaning processing of hard and/or soft surfaces, such as metal and/or plastic surfaces, comprising:
- at least one alkaline source,
- at least one polyethylene glycol, and
- at least one corrosion inhibitor; wherein
the weight-% ratio of the alkaline source to the polyethylene glycol is about > 30 : 1; and wherein the weight-% of the components are based on the total weight of the mild alkaline solid cleaning composition.
The weight -% ratio of the alkaline source to the polyethylene glycol can be > 30 : 1 to > 3000 : 1, preferably about > 31 : 1 to > 300 : 1, further preferred about > 32 : 1 to > 100 : 1, and also preferred about > 32.5 : 1 to > 35 : 1.
According to one embodiment the mild alkaline solid cleaning composition, suitable for automated cleaning processing of hard and/or soft surfaces, such as metal and/or plastic surfaces, comprising:
- about > 10 wt.-% of at least one alkaline source,
- about > 0.1 of at least one polyethylene glycol, and
- about > 20 wt.-% of at least one corrosion inhibitor;
wherein the weight-% of the components are based on the total weight of the mild alkaline solid cleaning composition.
It has surprisingly found, that the mild alkaline solid cleaning composition of the invention, is suitable for automated cleaning processing of hard and/or soft surfaces, such as metal and/or plastic surfaces, in particular metal instruments. The mild alkaline solid cleaning composition comprises a very low content of polyethylene glycol and an increased amount of at least one corrosion inhibitor that makes it extremely sensitive to metal articles, metal surfaces, plastic articles and/or plastic surfaces. For example, the mild alkaline solid cleaning composition according to the invention may provide good cleaning performances even though the weight-% ratio of alkaline source to polyethylene glycol can be for example in the range from about > 30 : 1 to about < 3000 : 1, based on the total weight of the mild alkaline solid cleaning composition.
The weigh-% ratio of alkaline source to polyethylene glycol can be in the range from about > 30 : 1 to about < 3000 : 1, preferably about > 31 : 1 to about < 300 : 1, further preferred about > 32 : 1 to about < 150 : 1, about > 32 : 1 to about < 100 : 1, about > 32 : 1 to about < 50 : 1, and also preferred about > 32.5 : 1 to about < 35 : 1, wherein the weight-% of the components are based on the total weight of the mild alkaline solid cleaning composition.
The term "alkaline sensitive metal" identifies those metals that exhibit corrosion and/or discoloration when exposed to an aqueous alkaline solution.
An aqueous alkaline solution is an aqueous solution having a pH that is greater than about 8. Exemplary alkaline sensitive metals include soft metals such as aluminum, nickel, tin, zinc,/copper, brass, bronze, and mixtures thereof. Aluminum and aluminum alloys are common alkaline sensitive metals that can be cleaned by the cleaning mild alkaline solid cleaning compositions.
References herein to a "solid" composition are to those, which are solid at about 15° C and up to about 60° C. Preferably, the mild alkaline solid cleaning composition of the present invention may be at about 15° C and up to about 60° C form stable and/or rigid.
A solvent, preferably water, can be added add. 100 wt.-% to the mild alkaline solid cleaning composition of the invention. The solvent content, such as the water content, of the mild alkaline solid cleaning composition according to the invention is simply determined by subtracting the amounts of all the usual components from 100 wt. %.
The weight-% (wt.-%) of the components are calculated based on the total weight amount of the mild alkaline solid cleaning composition, if not otherwise stated.
The ratio of components of the mild alkaline solid cleaning composition is parts by weight, if not otherwise stated.
The total amount of all components of the mild alkaline solid cleaning composition does not exceed 100 wt.-%.
It should be understood that the addition of other surfactants to the solid as well as to a liquid mild alkaline cleaning composition, obtained by solving the mild alkaline solid cleaning composition, for automated cleaning processing of hard and/or soft surfaces is optional and can be omitted.
Preferably, the mild alkaline solid cleaning compositions are free of other surfactants, except polyethylene glycol.
It should be understood that the mild alkaline solid cleaning compositions can be free of a hydrotrope component.
It should be understood that the mild alkaline solid cleaning compositions can be free of a zeolite, except sodium disilicate.
It should be understood that the mild alkaline solid cleaning compositions can be free of at least one additive, preferably all additives, selected from the group of antimicrobials, fungicides, fragrances, dyes, antistatic agents, UV absorbers, reducing agents and/or buffering compounds.
The combination of an alkaline source in combination with a polyethylene glycol leads to an increased foam formation, thus not suitable for use in an automated cleaning processing. However, it has been surprisingly found, that at a specific ratio of the alkaline source to the polyethylene glycol provides a low foaming composition suitable for automated cleaning processing of hard and/or soft surfaces, such as metal articles, metal surfaces, plastic articles and/or plastic surfaces.
At the time of dissolution with the solvent, such as water, a spontaneous and intensive foam formation in the dispensing draw of an apparatus for cleaning processing as well as in the cleaning chamber is observed, if the ratio or concentration of polyethylene glycol in the mild alkaline solid cleaning composition of the present invention is selected to high.
However, reducing the amount of polyethylene glycol to a very low content leads to an improper cleaning result. It has been surprisingly found that the insufficient cleaning characteristics due to the very low content of polyethylene glycol can be compensated and improved by increasing the amount of corrosion inhibitor.
Whiteout being bonded to a specific theory, it is assumed by the inventor that the increased amount of corrosion inhibitor has a synergetic cleaning effect that allows to reduce the polyethylene glycol content. The decrease content of polyethylene glycol reduces unwanted foam generation including the formation of micro bubbles to an absolute minimum, which improves disinfection of the surfaces to be cleaned.
The specific ratio of the at least one corrosion inhibitor to polyethylene glycol according to the present invention provides a good cleaning effect in combination with no visible foaming as required for an automated processing of metal articles, metal surfaces, plastic articles and/or plastic surfaces.
No foam formation is observed for the compositions according to the present invention, especially in the dispensing draw of an apparatus for cleaning processing as well as in the cleaning chamber.
Due to none or marginal foam formation the automated pumping flow rate of water- dissolved composition according to the present invention is not affected.
Further, the cleaning and disinfection action of a mild alkaline solid cleaning composition of the present invention used in an automated washing process is surprisingly good, although the concentration of the polyethylene glycol in the mild alkaline solid cleaning composition of the present invention is extremely low due to the addition of an increased amount of at least one corrosion inhibitor.
An aqueous alkaline composition having a high pH are often more corrosive than an aqueous composition having a light acidic pH. The concentrated liquid composition of the invention can have a pH in the range of about > 12.5 pH to about < 13.5 pH.
In order to minimize the potential to corrode and/or discolor the metal surface, the pH of the ready-to-use aqueous alkaline solutions, that is used for soil removal or cleaning action in direct contact with the surface of the article to be cleaned, can be adjusted to a lower pH in the range of about > 9.5 pH to about < 11 pH.
The soil removal or cleaning action of an aqueous solution of the mild alkaline solid cleaning composition according to the present invention can be improved by adding at least one sequestering agent to the mild alkaline solid cleaning composition, preferably at least one sequestering agent that exhibits soil removal properties.
Alkaline Source
The source of alkalinity can be any source of alkalinity that is compatible with the other components of the cleaning composition and that will provide the use solution, i.e. concentrated liquid composition as well as the ready-to-use liquid mild alkaline cleaning solution with the desired pH.
Exemplary sources of alkalinity include alkali metal hydroxides, alkali metal salts, phosphates, amines, and mixtures thereof.
Exemplary alkali metal hydroxides include sodium hydroxide, potassium hydroxide, and lithium hydroxide.
Exemplary alkali metal salts include sodium carbonate, trisodium phosphate, potassium carbonate, and mixtures thereof.
Exemplary phosphates include sodium pyrophosphate, potassium pyrophosphate, and mixtures thereof.
Exemplary amines include alkanolamine selected from the group comprising triethanolamine, monoethanolamine, diethanolamine, and mixtures thereof.
The source of alkalinity, preferably an alkali metal hydroxide, may be added to the composition in a variety of forms, including for example in the form of solid beads, dissolved in an aqueous solution or a combination thereof. Alkali metal hydroxides are commercially available as pellets or beads having a mix of particle sizes ranging from 12-100 U. S. mesh, or as an aqueous solution, as for example, as about 45 wt. %, about 50 wt. % and about 73 wt. % solution.
According to the invention, the mild alkaline solid cleaning composition may comprises about > 10 wt.-% to about < 35 wt.-%, preferably about > 13 wt.-% to about < 24 wt.-%, and more preferred about > 15 wt.-% to about < 20 wt.-%, of at least one alkaline source, preferably sodium hydroxide; wherein the weight-% of the components are based on the total weight of the mild alkaline solid cleaning composition.
Polyethylene Glycol
A suitable polyethylene glycol for use in the present invention can have an average mol weight (MW) in the range of about > 4000 to about < 12000, preferably about > 6000 to about < 10000 and more preferred of about > 7000 to about < 8000. Polyethylene glycol that can be used are marketed for example by BASF under the tradename PLURIOL®.
According to the invention, the mild alkaline solid cleaning composition may comprise about > 0.1 wt.-% to about < 1 wt.-%, preferably about > 0.2 wt.-% to about < 0.8 wt.-%, further preferred about > 0.3 wt.-% to about < 0.7 wt.-%, and more preferred about > 0.4 wt.-% to about < 0.6 wt.-%, and most preferred about 0.5 wt.-%, of at least one polyethylene glycol, preferably a polyethylene glycol with an average mol weight in the range of 4.000 to 12.000, and more preferred a polyethylene glycol having an average mol weight of about 8,000; wherein the weight-% of the components are based on the total weight of the mild alkaline solid cleaning composition.
Corrosion Inhibitor
According to the present invention, at least one corrosion inhibitor, preferably at least two corrosion inhibitors, in large amounts, are used to compensate the extreme low polyethylene glycol content of the composition in order to reach an excellent cleaning performance as well as to prevent the corrosion of an article to be cleaned.
Preferably a silicate(s) corrosion inhibitor and more preferred a disilicate corrosion inhibitor can be used in the solid composition according to the present invention. The silicate(s) and/or disilicate corrosion inhibitor can be an alkali silicate and/or alkali disilicate.
Other inhibitors that can be used can be selected from the group comprising calcium acetate, calcium chloride, calcium gluconate, calcium phosphate, calcium borate, calcium carbonate, calcium citrate, calcium lactate, calcium sulfate, calcium tartrate, benzotriazole, 1,2,3-benzotriazole and mixtures thereof.
More preferred, the corrosion inhibitor is a heterocyclic compound, a triazole derivate, such as a benzotriazole or 1,2,3-benzotriazole and mixtures thereof.
Exemplary silicates include sodium metasilicates, sesquisilicates, orthosilicates, potassium silicates, and mixtures thereof. However, most preferred can be sodium silicate.
The silicates may comprise at least one crystalline layer-forming silicate of the general formula NaMSix02x+l .yH20, wherein M represents sodium or hydrogen, x is a number from about 1.9 to about 22, preferably about 1.9 to about 4 and y stands for a number from about 0 to about 33.
The crystalline layer- forming silicates of the formula NaMSix022x+l .yH20 are marketed for example by Clariant GmbH (Germany) under the trade names Na-S S, eg. Na-S S-1 (Na2Si22045.xH20, Kenyait), Na-S S-2 (Na2Sil4029.xH20, Magadiit), Na- SKS-3 (Na2Si8017.xH20) or Na-SKS-4 ( a2Si409.xH20, Makatit).
Crystalline, layered silicates of the above formula, in which x stands for 2, are particularly suitable for the purposes of the present invention.
Na-SKS-5 (alpha -Na2Si205), Na-SKS-7 (beta -Na2Si205, Natrosilit), Na-SKS-9 (NaHSi205.H20), Na-SKS-10 (NaHSi205.3H20, Kanemit), Na-SKS-11 (t-Na2Si205) and Na-SKS-13 (NaHSi205) are most notably suitable, particularly Na-SKS-6 (delta -Na2Si205).
In the context of the present application, silicates can comprise a content by weight of crystalline layered silicates of formula NaMSix02x+l.yH20 of 0.1 to 20 wt. %, preferably about 0.2 to about 15 wt. % and particularly about 0.4 to about 10 wt. %, each based on the total weight of the corrosion inhibitor agent.
Particularly preferred are especially those that have a total silicate content about > 0 and below about 7 wt.- %, advantageously below about 6 wt.- %, preferably below about 5 wt.- %, particularly preferably below about 4 wt.- %, quite particularly preferably below about 3 wt. -% and especially below about 2.5 wt.- %, wherein this silicate, based on the total weight of the comprised silicate, is advantageously at least about 70 wt.- %, preferably at least about 80 wt.- % and especially at least about 90 wt.- % of a silicate of the general formula NaMSix02x+l.yH20.
However, other corrosion inhibitors can be suitable added to the mild alkaline solid cleaning composition of this invention include magnesium and/or zinc ions and Ca (N02) 2. Preferably, the metal ions are provided in water-soluble form.
Examples of useful water-soluble forms of magnesium and zinc ions are the water- soluble salts thereof including the chlorides, nitrates and sulfates of the respective metals. If any of the alkalinity providing agents are the alkali metal carbonates, bicarbonates or mixtures of such agents, magnesium oxide can be used to provide the Mg ion. The magnesium oxide is water soluble and is a preferred source of Mg ions.
In order to maintain the dispersibility of the magnesium and/or zinc corrosion inhibitors in aqueous solution, and in the presence of agents which would otherwise cause precipitation of the zinc or magnesium ions, e. g. , carbonates, phosphates, etc. , it might be advantageous to include a carboxylated polymer to the solution.
The useful carboxylated polymer corrosion inhibitors may be generically categorized as water-soluble carboxylic acid polymers such as polyacrylic and polymethacrylic acids or vinyl addition polymers, in addition to the acid-substituted polymers used in the present invention.
Of the vinyl addition polymer corrosion inhibitors contemplated, maleic anhydride copolymers as with vinyl acetate, styrene, ethylene, isobutylene, acrylic acid and vinyl ethers are examples.
The polymers tend to be water-soluble or at least colloidally dispersible in water. The molecular weight of these polymers may vary over a broad range although it is preferred to use polymers having average molecular weights ranging between about 1,000 up to about 1,000, 000. These polymers have a molecular weight of about 100,000 or less and between about 1,000 and about 10,000.
The polymers or copolymers (either the acid-substituted polymers or other added polymers) may be prepared by either addition or hydrolytic techniques. Thus, maleic anhydride copolymers are prepared by the addition polymerization of maleic anhydride and another comonomer such as styrene.
The low molecular weight acrylic acid polymer corrosion inhibitors may be prepared by addition polymerization of acrylic acid or its salts either with itself or other vinyl comonomers.
Alternatively, such polymers may be prepared by the alkaline hydrolysis of low molecular weight acrylonitrile homopolymers or copolymers.
The corrosion inhibitor can be used in quantities of about > 0 to about < 10, preferably about > 0.05 to about < 5, also preferred about > 0.1 to about < 3 and more preferred of about > 0.5 to about < 2; wherein the weight-% of the components are based on the total weight of the composition.
According to the invention, the mild alkaline solid cleaning composition may comprises about > 15 wt.-% to about < 40 wt.-%, preferably about > 18 wt.-% to about < 35 wt.-%, further preferred about > 20 wt.-% to about < 28 wt.-%, and more preferred about > 23 wt.-% to about < 25 wt.-%, of at least one corrosion inhibitor, preferably sodium disilicate, and more preferred at least two corrosion inhibitors, preferably a benzotriazol and sodium disilicate and most preferred 1,2,3-benzotriazole and sodium disilicate; wherein the weight-% of the components are based on the total weight of the mild alkaline solid cleaning composition.
Threshold Inhibitor/Crystal Modifier
The mild alkaline solid cleaning composition according to the present invention can comprise at least one threshold inhibitor/crystal modifier.
The threshold inhibitor/crystal modifier can be selected from the group comprising salts of phosphonocarboxylic acids, phosphonates, salts of 1-hydroxyethylidene -1,1,- diphosphonic acid (HEDP), salts of acid substituted polymers, and mixtures thereof, preferably salts of acid substituted polymers of monomers of acrylate, methacrylate, salts of polyitaconic acid, salts of polymaleic acid, and mixtures thereof. In particular preferred are salts of polyacrylic acid.
The amount of threshold inhibitor/crystal modifier can be about > 0.5 wt.-% to about < 15 wt.-%, preferably about > 1 wt.-% to about < 10 wt.-%, and more preferred about > 3 wt- % to about < 5 wt.-% of at least one threshold inhibitor/crystal modifier, preferably the threshold inhibitor/crystal modifier is a salt of a polyacrylic acid; wherein the weight-% of the components are based on the total weight of the mild alkaline solid cleaning composition.
Sequestering Agent
The mild alkaline solid cleaning composition according to the present invention can comprise at least one sequestering agent.
The sequestering agent can be selected from the group of sodium gluconate, pentasodium salt of diethylenetriamine pentaacetic acid, sodium glucoheptonate, salts of ethylene diamine tetraacetic acid, salts of ethylene diamine tetraacetic acid, salts of hydroxyethyl ethylene diamine triacetic acid, salts of hydroxyethyl ethylene diamine triacetic acid, salts of nitrilotriacetic acid, salts of nitrilotriacetic acid, diethanolglycine sodium salt, ethanoldiglycine disodium salt, salts of hydroxymonocarboxylic acid compounds, salts of hydroxydicarboxylic acid compounds, salts of amine containing carboxylic acids, tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate (GDLA) and mixtures thereof.
In particular preferred is at least one sequestering agent that exhibits soil removal properties when used at a pH of at least about 10.0. The sequestering agent is provided for tying up metals in the soil to assist in cleaning and detergency. The sequestering agent can be provided as part of the mild alkaline solid cleaning composition. Exemplary sequestering agents that exhibit soil removal properties at a pH of greater than about 10.0 that can be used according to the invention include sodium gluconate, pentasodium salt of diethylenetriamine pentaacetic acid (available under the name Versenex 80), sodium glucoheptonate, ethylene diamine tetraacetic acid (EDTA), salts of ethylene diamine tetraacetic acid, hydroxyethyl ethylene diamine triacetic acid (HEDTA), salts of hydroxyethyl ethylene diamine triacetic acid, nitrilotriacetic acid (NTA), salts of nitrilotriacetic acid, diethanolglycine sodium salt (DEG), ethanoldiglycine disodium salt (EDG), tetrasodium N,N-bis(carboxylatomethyl)-L-
glutamate (GLDA), methyl glycine diacetic acid (MGDA)and mixtures thereof. Exemplary salts of ethylene diamine tetraacetic acid include disodium salts, tetrasodium salts, diammonium salts, and trisodium salts. An exemplary salt of hydroxy ethyl ethylene diamine triacetic acid is the trisodium salt.
It should be understood that the sequestering agent can include mixtures of different sequestering agents.
The amount of sequestering agent can be about > 5 wt.-% to about < 40 wt.-%, preferably about > 15 wt.-% to about < 30 wt.-%, and more preferred about > 20 wt.-% to about < 25 wt.-% of at least one sequestering agent, preferably the sequestering agent is a salt of an amine containing carboxylic acid, and more preferred terasodium N,N- bis(carboxylatomethyl)-L-glutamate (GLDA); wherein the weight-% of the components are based on the total weight of the mild alkaline solid cleaning composition.
Solvents
Suitable solvents include, but are not limited to, water, alcohols, glycols, glycol ethers, esters, and the like, or combinations thereof. Suitable alcohols include, but are not limited to, ethanol, isopropanol (propan-2-ol), 2-butoxy ethanol (butyl glycol), 1-decanol, benzyl alcohol, glycerin, monoethanolamine (MEA), and the like, or combinations thereof.
Suitable glycols include, but are not limited to, ethylene glycol (monoethylene glycol or MEG), diethylene glycol (propylene glycol or butoxy diglycol or DEG), triethylene glycol (TEG), tetraethylene glycol (TETRA EG), glycerin, propylene glycol, dipropylene glycol, hexylene glycol, and the like, or combinations thereof. Preferably the composition comprises at least two solvents and more preferred the composition comprises water and hexylene glycol.
The amount of an additional solvent that is not water, preferably hexylene glycol, can be about > 0.1 wt.-% to about < 5 wt.-%, preferably about > 0.4 wt.-% to about < 1 wt.-%, and more preferred about > 0.6 wt.-% to about < 0.8 wt.-%; wherein the weight-% of the components are based on the total weight of the mild alkaline solid cleaning composition.
Water can be added add 100 wt.-%; wherein the weight-% of the components are based on the total weight of the mild alkaline solid cleaning composition.
Mild alkaline solid cleaning composition
According to one embodiment of the invention, the mild alkaline solid cleaning composition may comprise:
- about > 10 wt.-% to about < 35 wt.-%, preferably about > 13 wt.-% to about < 24 wt.-%, and more preferred about > 15 wt.-% to about < 20 wt.-%, of at least one alkaline source, preferably sodium hydroxide;
- about > 0.1 wt.-% to about < 1 wt.-%, preferably about > 0.2 wt.-% to about < 0.8 wt.-%, further preferred about > 0.3 wt.-% to about < 0.7 wt.-%, and more preferred about > 0.4 wt.-% to about < 0.6 wt.-%, and most preferred about 0.5 wt.-%, of at least one polyethylene glycol, preferably a polyethylene glycol with an average mol weight in the range of 4.000 to 12.000, and more preferred a polyethylene glycol having an average mol weight of about 8,000; and
- about > 15 wt.-% to about < 40 wt.-%, preferably about > 18 wt.-% to about < 35 wt.-%, further preferred about > 20 wt.-% to about < 28 wt.-%, and more preferred about > 23 wt.- % to about < 25 wt.-%, of at least one corrosion inhibitor, preferably sodium disilicate, and more preferred at least two corrosion inhibitors, preferably a benzotriazol and sodium disilicate;
- a solvent, preferably water, is added add. 100 wt.-%; wherein
the weight-% of the components are based on the total weight of the of the mild alkaline solid cleaning composition.
According to another embodiment of the invention, the mild alkaline solid cleaning composition may comprise:
- about > 10 wt.-% to about < 35 wt.-%, preferably about > 13 wt.-% to about < 24 wt.-%, and more preferred about > 15 wt.-% to about < 20 wt.-%, of at least one alkaline source, preferably sodium hydroxide;
- about > 0.1 wt.-% to about < 1 wt.-%, preferably about > 0.2 wt.-% to about < 0.8 wt.-%, further preferred about > 0.3 wt.-% to about < 0.7 wt.-%, and more preferred about > 0.4 wt.-% to about < 0.6 wt.-%, and most preferred about 0.5 wt.-%, of at least one polyethylene glycol, preferably a polyethylene glycol with an average mol weight in the range of 4.000 to 12.000, and more preferred a polyethylene glycol having an average mol weight of about 8,000 ; and
- about > 15 wt.-% to about < 40 wt.-%, preferably about > 18 wt.-% to about < 35 wt.-%, further preferred about > 20 wt.-% to about < 28 wt.-%, and more preferred about > 23 wt- % to about < 25 wt.-%, of at least one corrosion inhibitor, preferably sodium disilicate, and more preferred at least two corrosion inhibitors, preferably a benzotriazol and sodium disilicate;
- about > 0.5 wt.-% to about < 15 wt.-%, preferably about > 1 wt.-% to about < 10 wt.-%, and more preferred about > 3 wt.-% to about < 5 wt.-% of at least one threshold inhibitor/crystal modifier, preferably the threshold inhibitor/crystal modifier is a salt of a polyacrylic acid;
- about > 5 wt.-% to about < 40 wt.-%, preferably about > 15 wt.-% to about < 30 wt.-%, and more preferred about > 20 wt.-% to about < 25 wt.-% of at least one sequestering agent, preferably the sequestering agent is a salt of an amine containing carboxylic acid, and more preferred terasodium N,N-bis(carboxylatomethyl)-L-glutamate (GLDA);
- a solvent, preferably water, is added add. 100 wt.-%; wherein
the weight-% of the components are based on the total weight of the of the mild alkaline solid cleaning composition.
Liquid mild alkaline cleaning composition
Another object of the present invention is directed to a liquid mild alkaline cleaning composition obtained from the mild alkaline solid cleaning composition of the invention. The cleaning compositions according to the invention can take the form of a single concentrate or multiple concentrates that can be diluted and combined to provide a ready-to-use liquid mild alkaline cleaning solution. The ready-to-use liquid mild alkaline cleaning solution can be directly used to clean articles and need not to be diluted.
The ready-to-use liquid composition according to the invention may be used to clean articles having a metal surface, such as surgical, medical, and dental instruments, including endoscopes.
The solution can be in the form of a concentrate that can be diluted with a solvent, such as water, to provide a ready-to-use liquid mild alkaline cleaning solution that can be used for cleaning applied to articles having a metal surface, such as surgical, medical, and dental instruments.
In addition, the solutions can be provided as a relatively dilute solution that can be, without the addition of water, to provide an organic ready-to use solution, for example an alcohol based ready-to use solution, that can be for cleaning applied to articles having a metal surface, such as surgical, medical, and dental instruments.
It is advantageous to provide the solution as a concentrate and then to dilute the concentrate at the situs of use in order to decrease transportation costs associated with transporting large amounts of solvent, such as water.
The concentrate liquid composition and/or the ready-to-use liquid mild alkaline cleaning solution can be used in an automated washing process for cleaning and disinfection metal and plastic surfaces, in particular metal surfaces of surgical, medical, and dental instruments including endoscopes, from body fluids, such as blood, lipids, contrast agent and synovial fluids from joints adhere to the metal surface used during a procedure.
Concentrated mild alkaline liquid composition
The source of alkalinity and addition of the solvent, preferably water, are provided so that the concentrated, preferably aqueous, liquid composition of the mild alkaline solid cleaning composition according to the present invention may have a pH in the range of about 12 pH to about 14 pH, preferably a pH in the range of about 12.5 pH to about 13.5 pH and more preferred a pH of about 13 pH.
The ratio of the solvent, preferably water, to solid, to provide a concentrated liquid composition, preferably an aqueous solution, of the mild alkaline solid cleaning composition can be in the range of from about 200 : 1 to about 10 : 1, preferably about 100 : 1 to about 12 : 1, further preferred about 50 : 1 to about 15 : 1, also preferred about 40 : 1 to about 17 : 1 and in particular preferred about 30 : 1 to 20 : 1.
According to one embodiment of the invention, the alkaline concentrated liquid composition can comprise:
- about > 0.07 wt.-% to about < 3.5 wt.-%, preferably about > 0.3 wt.-% to about < 1.6 wt- %, and more preferred about > 0.5 wt.-% to about < 1 wt.-%, of at least one alkaline source, preferably sodium hydroxide;
- about > 0.0005 wt.-% to about < 0.1 wt.-%, preferably about > 0.002 wt.-% to about < 0.07 wt.-%, further preferred about > 0.006 wt.-% to about < 0.05 wt.-%, and more preferred about > 0.01 wt.-% to about < 0.35 wt.-%, and most preferred about 0.02 wt.-%, of at least one polyethylene glycol, preferably a polyethylene glycol with an average mol weight in the range of 4.000 to 12.000, and more preferred a polyethylene glycol having an average mol weight of about 8,000; and
- about > 0.075 wt.-% to about < 4 wt.-%, preferably about > 0.36 wt.-% to about < 2.5 wt.- %, further preferred about > 0.5 wt.-% to about < 1.5 wt.-%, and more preferred about > 0.7 wt.-% to about < 1.25 wt.-%, of at least one corrosion inhibitor, preferably sodium disilicate, and more preferred at least two corrosion inhibitors, preferably a benzotriazol and sodium disilicate;
- a solvent, preferably water, is added add. 100 wt.-%;
wherein the weight-% of the components are based on the total weight of the alkaline concentrated liquid composition.
According to another embodiment of the invention, the mild alkaline solid cleaning composition can comprise:
- about > 0.07 wt.-% to about < 3.5 wt.-%, preferably about > 0.3 wt.-% to about < 1.6 wt- %, and more preferred about > 0.5 wt.-% to about < 1 wt.-%, of at least one alkaline source, preferably sodium hydroxide;
- about > 0.0005 wt.-% to about < 0.1 wt.-%, preferably about > 0.002 wt.-% to about < 0.07 wt.-%, further preferred about > 0.006 wt.-% to about < 0.05 wt.-%, and more preferred about > 0.01 wt.-% to about < 0.35 wt.-%, and most preferred about 0.02 wt.-%, of at least one polyethylene glycol, preferably a polyethylene glycol with an average mol weight in the range of 4.000 to 12.000, and more preferred a polyethylene glycol having an average mol weight of about 8,000; and
- about > 0.075 wt.-% to about < 4 wt.-%, preferably about > 0.36 wt.-% to about < 2.5 wi- %, further preferred about > 0.5 wt.-% to about < 1.5 wt.-%, and more preferred about > 0.7 wt.-% to about < 1.25 wt.-%, of at least one corrosion inhibitor, preferably sodium disilicate, and more preferred at least two corrosion inhibitors, preferably a benzotriazol and sodium disilicate;
- about > 0.0025 wt.-% to about < 1.5 wt.-%, preferably about > 0.02 wt.-% to about < 0.7 wt.-%, and more preferred about > 0.1 wt.-% to about < 0.25 wt.-% of at least one threshold inhibitor/crystal modifier, preferably the threshold inhibitor/crystal modifier is a salt of a polyacrylic acid;
- about > 0.025 wt.-% to about < 4 wt.-%, preferably about > 0.3 wt.-% to about < 2 wt.-%, and more preferred about > 0.6 wt.-% to about < 1.25 wt.-% of at least one sequestering agent, preferably the sequestering agent is a salt of an amine containing carboxylic acid, and more preferred terasodium N,N-bis(carboxylatomethyl)-L-glutamate (GLDA);
- a solvent, preferably water, is added add. 100 wt.-%; wherein
the weight-% of the components are based on the total weight of the alkaline concentrated liquid composition.
Ready-to-use liquid mild alkaline cleaning solution
The source of alkalinity and addition of solvent, preferably water, are provided so that the aqueous ready-to-use liquid mild alkaline cleaning solution according to the present
invention may have a pH in the range of about > 9.5 pH to about < 11.5 pH and preferably a pH in the range of about > 10.0 pH to about < 11 pH.
The ratio of the solvent, preferably water, to solid, to provide a ready-to-use liquid mild alkaline cleaning solution, preferably an aqueous solution, of the mild alkaline solid cleaning composition can be in the range of from about 60,000 : 1 to about 100 : 1, preferably about 30,000 : 1 to about 300 : 1, further preferred about 10,000 : 1 to about 500 : 1, also preferred about 5,000 : 1 to about 750 : 1 and in particular preferred about 2,500 : 1 to about 1,000 : 1.
According to one embodiment of the invention, the ready-to-use liquid mild alkaline cleaning solution can comprise:
- about > 0.0002 wt.-% to about < 0.035 wt.-%, preferably about > 0.0009 wt.-% to about < 0.016 wt.-%, and more preferred about > 0.0015 wt.-% to about < 0.01 wt.-%, of at least one alkaline source, preferably sodium hydroxide;
- about > 0.0000015 wt.-% to about < 0.001 wt.-%, preferably about > 0.000006 wt.-% to about < 0.0007 wt.-%, further preferred about > 0.00002 wt.-% to about < 0.0005 wt.-%, and more preferred about > 0.00003 wt.-% to about < 0.0035 wt.-%, and most preferred about 0.0002 wt.-%, of at least one polyethylene glycol, preferably a polyethylene glycol with an average mol weight in the range of 4.000 to 12.000, and more preferred a polyethylene glycol having an average mol weight of about 8,000; and
- about > 0.0002 wt.-% to about < 0.04 wt.-%, preferably about > 0.001 wt-% to about < 0.025 wt.-%, further preferred about > 0.0015 wt.-% to about < 0.015 wt.-%, and more preferred about > 0.002 wt.-% to about < 0.01 wt.-%, of at least one corrosion inhibitor, preferably sodium disilicate, and more preferred at least two corrosion inhibitors, preferably a benzotriazol and sodium disilicate;
- a solvent, preferably water, is added add. 100 wt.-%; wherein
the weight-% of the components are based on the total weight of the ready-to-use liquid mild alkaline cleaning solution.
According to another embodiment of the invention, the ready-to-use liquid mild alkaline cleaning solution can comprise:
- about > 0.0002 wt.-% to about < 0.035 wt.-%, preferably about > 0.0009 wt.-% to about < 0.016 wt.-%, and more preferred about > 0.0015 wt.-% to about < 0.01 wt.-%, of at least one alkaline source, preferably sodium hydroxide;
- about > 0.000001 wt.-% to about < 0.001 wt.-%, preferably about > 0.000006 wt.-% to about < 0.0007 wt.-%, further preferred about > 0.00002 wt.-% to about < 0.0005 wt.-%,
and more preferred about > 0.00003 wt.-% to about < 0.0035 wt.-%, and most preferred about 0.0002 wt.-%, of at least one polyethylene glycol, preferably a polyethylene glycol with an average mol weight in the range of 4.000 to 12.000, and more preferred a polyethylene glycol having an average mol weight of about 8,000; and
- about > 0.0002 wt.-% to about < 0.04 wt.-%, preferably about > 0.001 wt.-% to about < 0.025 wt.-%, further preferred about > 0.0015 wt.-% to about < 0.015 wt.-%, and more preferred about > 0.002 wt.-% to about < 0.01 wt.-%, of at least one corrosion inhibitor, preferably sodium disilicate, and more preferred at least two corrosion inhibitors, preferably a benzotriazol and sodium disilicate;
- about > 0.000007 wt.-% to about < 0.015 wt.-%, preferably about > 0.00006 wt.-% to about < 0.007 wt.-%, and more preferred about > 0.0003 wt.-% to about < 0.0025 wt.-% of at least one threshold inhibitor/crystal modifier, preferably the threshold inhibitor/crystal modifier is a salt of a polyacrylic acid;
- about > 0.0007 wt.-% to about < 0.04 wt.-%, preferably about > 0.001 wt-% to about < 0.02 wt.-%, and more preferred about > 0.002 wt.-% to about < 0.01 wt.-% of at least one sequestering agent, preferably the sequestering agent is a salt of an amine containing carboxylic acid, and more preferred terasodium N,N-bis(carboxylatomethyl)-L-glutamate (GLDA);
- a solvent, preferably water, is added add. 100 wt.-%; wherein
the weight-% of the components are based on the total weight of the ready-to-use liquid mild alkaline cleaning solution.
Manufacture of the mild alkaline solid cleaning composition
There are a number of processes known in prior art to provide a solidified product. For example, all components of the mild alkaline solid cleaning composition can be mixed together or added portionwise or one after the other. A cast process then solidifies the heated slurry, e.g. the solidification can erupt after cooling down a NaOH melt by crystallization.
Cleaning Apparatus
Another object of the invention is directed to a cleaning apparatus. The cleaning apparatus is used to clean and to disinfect articles having a metal surface, such as surgical, medical, and dental instruments.
The cleaning apparatus includes at least a first tank to receive the mild alkaline solid cleaning composition of the invention; at least a second component tank to receive water
diluted concentrated composition or a ready-to-use liquid mild alkaline cleaning solution of said mild alkaline solid cleaning composition of the invention, a water feed, and a use solution line; and optional a third component tank to receive a day portion of the concentrated composition or a ready-to-use liquid mild alkaline cleaning solution of the invention.
The first component tank is provided for containing the mild alkaline solid cleaning composition of the invention. The first component tank can be provided for mixing water to the mild alkaline solid cleaning composition to provide a concentrated liquid composition. The mild alkaline solid cleaning composition can be mixed with water in a circulation method to obtain a defined alkaline aqueous concentrated liquid composition.
The second component tank is provided for receiving the aqueous concentrated liquid composition or for mixing water to the alkaline aqueous concentrated liquid composition to provide a ready-to-use liquid mild alkaline cleaning solution.
The optional third component tank is provided for receiving a day portion of the aqueous concentrated liquid composition or for mixing water to the alkaline aqueous concentrated liquid composition to provide a day portion of a ready-to-use liquid mild alkaline cleaning solution.
The water feed is provided for conveying water to the first tank, second tank (makeup tank) and/or third tank (day tank) for dissolving the mild alkaline solid cleaning composition (first tank) and/or for providing an aqueous concentrated alkaline liquid composition or a ready-to-use liquid mild alkaline cleaning solution (second tank) and/or for providing an aqueous ready-to-use liquid mild alkaline cleaning solution (third tank). It can be preferred that the aqueous concentrated alkaline liquid composition is transferred to the day tank, by the time the defined concentration, pH, volume and/or temperature is reached.
However, the makeup tank (second tank) and more preferred the third tank (day tank) can be used to receive and stock the alkaline aqueous concentrated liquid composition or the ready-to-use liquid mild alkaline cleaning solution. Most preferred is to provide the ready-to- use liquid mild alkaline cleaning solution at the place of use, for example in an applicator, by adding sufficient water. The aqueous concentrated alkaline liquid composition can be conveyed from the second tank or a day tank (optional third tank) to a dispenser and the dispenser sprays out the ready-to-use liquid mild alkaline cleaning solution at the place of operation in a defined concentration.
The solution line is provided for conveying solution from the second container to a use solution applicator.
In more detail, the mild alkaline solid cleaning composition of the invention can be used in combination with a healthcare solid dispenser. This dispenser sprays out the mild alkaline solid cleaning composition of the invention having the form of a capsule in a circulation method to a defined concentration. This alkaline aqueous concentrated liquid composition is collected in a makeup tank and transferred to a day tank as soon as the concentration and referring conductivity has reached the defined level. From there the pumps of the washer disinfectors dose the cleaning alkaline aqueous concentrated liquid composition in the cleaning cycle of the reprocessing step. The solid can be diluted to a 5% alkaline aqueous concentrated liquid composition in the dispenser.
The ready-to-use liquid mild alkaline cleaning solution or the concentrated liquid composition can be in any form including liquid, gel, paste and slurry.
The cleaning solutions, i.e. ready-to-use liquid mild alkaline cleaning solution and/or the concentrated liquid composition, are suitable to treat any metal surface contaminated with a wide variety of contaminants.
Exemplary contaminants include body fluids, such as blood, lipids and synovial fluids and chemical residues.
The aqueous cleaning solutions of this invention, i.e. the aqueous alkaline ready-to-use liquid mild alkaline cleaning solution and/or the concentrated aqueous alkaline liquid composition, may be used at any temperature, including an elevated temperature of from about 30° C to about 70° C, preferably about 45° C to about 60° C and more preferred about 55° C. After contact with the cleaning solution, the solution is removed from the metal or plastic surface.
The contact time of the aqueous cleaning solution in an automated process, i.e. ready- to-use liquid mild alkaline cleaning solution and/or the concentrated liquid composition, with the metal substrates will vary depending upon the degree of contamination but broadly will range between a few seconds or about > 1 minute to about < 30 minutes, with about > 3 minutes to about < 15 minutes being more typical and most preferred is about > 5 minutes to about < 10 minutes.
According to a preferred embodiment of the invention the cleaning apparatus may comprise:
(a) a first container comprising an alkaline solid composition according to claims 1 to 10;
(b) a second container comprising a concentrated liquid composition of the solid composition according to claim 12 or 14 having a pH of about > 12.5 to about < 13.5, preferably a pH of about 13;
(c) optional a third container comprising a day solution of the concentrated liquid
composition or a ready to use solution having a pH of about > 9.5 to about < 11.0;
(c) a water feed for conveying water to the first container for forming said solution from water;
(d) a solution line for conveying solution from the first container to the second container;
(e) optional a third container that is connected with the second container with a solution line for conveying solution from the second container to the third container; and
(f) a use solution line for conveying the use solution from the second container and/or third container to a use solution applicator and/or to the place of use.
The following examples are presented to help illustrate the invention and should not be construed as limiting the invention.
When processing solids in the cast process there are different ways to ensure a solidification of the product. The solidification can erupt after cooling down a NaOH melt by crystallization, e.g. with silicates and polyethylene glycol. Foaming of this formula was observed to an extent that was not acceptable in the field of automated reprocessing. If the cleaner generates too much foam in the washer, the cleaning efficiency goes down due to lack of mechanical agitation in the washer.
It was observed that polyethylene glycol in combination with NaOH and heat lead to a high foaming composition. The formation of foam lowers in particular the cleaning properties, due to the loss of mechanical agitation. Further, pumping of foam dramatically reduces the liquid flow rates, thus causes dosing and transport problems in the sump, liquid conduits, as well as in the dispensing drawer. Thus, foam is not acceptable in an automated washer. Cleaning efficacy tests have shown that that the results without polyethylene glycol in the formula were not as good as with polyethylene glycol in the formula.
To achieve a good level of cleaning efficacy it was successfully tried to add a small amount of polyethylene glycol to the NAOH based formulation. With this addition of a minor amount of polyethylene glycol (PEG) the composition of the invention has a surprising cleaning efficacy due to none foam formation, if mixed with water, as sump solution or in the dispensing drawer.
Metal surfaces and/or plastic surfaces in need of cleaning are found in several locations. Exemplary locations include surgical instruments, medical instruments, and dental
instruments, sinks, cookware, utensils, machine parts, vehicles, tanker trucks, vehicle wheels, work surfaces, tanks, immersion vessels, spray washers, and ultrasonic baths.
The cleaning compositions of the present invention can be used for removing residues including blood, greases, cutting fluids, drawing fluids, machine oils, antirust oils such as cosmoline, carbonaceous soils, sebaceous soils, particulate matter, waxes, paraffins, used motor oil, fuels, etc..
Metal surfaces that can be cleaned include iron-based metals such as iron, iron alloys, e. g. steel, tin, aluminum, copper, tungsten, titanium, molybdenum, etc., for example. The structure of the metal surface to be cleaned can vary widely. Thus, the metal surface and/or plastic surface can be as a metal and/or plastic part of complex configuration, sheeting, coils, rolls, bars, rods, plates, disks, etc..
More preferred is the use of the liquid alkaline cleaning solution of the invention, in particular the ready-to-use-solution to clean metal and/or plastic articles, especially metal instruments, plastic instruments, instruments with a plastic surface and/or instruments with a metal surface.
Most preferred is the use of the liquid alkaline cleaning solution of the invention, in particular the ready-to-use-solution, to clean in an automated instrument processing metal and/or plastic articles, especially metal instruments, plastic instruments, instruments with a plastic surface and/or instruments with a metal surface.
Example
The following examples were carried out to illustrate the reduced foam formation of the cleaning compositions according to the invention.
The following alkaline concentrates were provided in a solid form:
All components of table 1 and 2 are mixed together. Then the slurry is mixed and heated to temperature of about 80° C for about 30 minutes. Thereafter, the mixed slurry is casted and allows cooling to room temperature, whereby a casted alkaline solid is formed.
Table 1
Solid alkaline concentrate of the invention
Foam Formation Test
This test method provides a basis to assess the foam formation properties of the liquid alkaline cleaning composition of the invention.
Foam testing equipment
250 ml long-necked glass cylinder
Rubber stopper to close the long-necked glass cylinder
Test method
An aqueous ready-to-use liquid mild alkaline cleaning solution is formed, wherein 1.0 g of examples El to E7 are dissolved in 100 ml of deionized water each.
100 ml of said aqueous ready-to-use liquid mild alkaline cleaning solution of examples El to E7 are added to a graduated 250 ml long-necked glass cylinder.
The long-necked glass cylinder was then turned up and down 20 x times in 20 seconds. Thereafter the glass cylinder was placed and the foam depth of each cylinder was
scaled in ml to determine the foam formation. This test was carried out at a temperature of the cleaning solution at ambient temperature, 20° C and 55° C. The foam height are given in ml.
The table 2 shows the result of the foam formation caused by the aqueous ready-to-use liquid mild alkaline cleaning solution of examples El to E7 obtained by the foam formation test.
Table 2
Foam Formation Test-Results
Material Compatibility Test
This test method provides a basis to assess the enhanced metal-surface-safeness of the liquid alkaline cleaning composition of the invention with respect to corrosion.
Corrosion testing equipment
350 ml wide-necked screw cap flasks for each test condition
Acetone
Aluminum test plates of 100 mm x 50 mm x 1.5 mm
(The aluminum test plates are cleaned with acetone before use)
Clean paper toweling
Stop watch
Drying oven
Analytical balance capable of weighing to the 0.0001 place.
Test method
The cleaning compositions El to E7 and comparative compositions VI to V14 were diluted with deionized water to a 0.8 wt.-% ready-to-use liquid mild alkaline cleaning solution. The weights of aluminum test plates of 100 mm x 50 mm x 1.5 mm were recorded and then placed in the center area of the bottom of a 350 ml wide-necked screw cap flask each. The aluminum test plates were completely submerged. Subsequently, each wide-necked screw cap flask was filed to the top with said 0.8 wt.-% ready-to-use liquid mild alkaline cleaning solution El to E7 and VI to V14 having a temperature of 23° C. The wide-necked screw cap flasks were closed with the cap and allow staying for 7 days at a temperature of 23° C. Thereafter, the aluminum test plates were removed, rinsed with deionized water, placed on a clean paper towel and allowed to dry at a temperature of 23° C. The aluminum test plates were then weighted and the weight was taken to the fourth place. Subsequently the aluminum test plates were returned in there wide-necked screw cap flasks for another 7 days. Thereafter, the aluminum test plates were removed, rinsed with deionized water, placed on a clean paper towel and allowed to dry at a temperature of 23° C. The aluminum test plates were then weighted and the weight was taken to the fourth place. Subsequently the aluminum test plates were returned again in there wide-necked screw cap flasks for another 7 days. The weight loss was calculated. Three tests were run for each experiment and the average weight loss was determined. The average weight loss for each aluminum test plates after treatment with said ready-to-use liquid mild alkaline cleaning solution obtained from El to E7 were about < 0.30 wt.-% and for VI to V14 about > 1 wt.-%.
Table 3
Comparative composition VI to V14
Components VI V2 V3 V4 V5 V6 V7
Wt.-% Wt.-% Wt.-% Wt.-% Wt.-% Wt.-% Wt.-%
Polyethylene glycol (PEG 2 3 5 6 9 10 12 8000)
Hexylene glycol — — — 0.6 0.6 0.6 0.6
Polyacrylic acid 6 6 5 5 5 5 4
NaOH 37 35 33 30 28 25 25
1 ,2,3-Benzotriazole 6 5 4 7
Disilicate 4 5 3
N,N- 25 22 22 bis(carboxylatomethyl)-L- glutamate (GLDA)
Water Add. Add. Add. Add. Add. Add. Add.
100 100 100 100 100 100 100
Components V8 V9 V10 Vl l V12 V13 V14
Wt.-% Wt.-% Wt.-% Wt.-% Wt.-% Wt.-% Wt.-%
Polyethylene glycol (PEG 2 4 6
4000) ... ... ... ...
Polyethylene glycol (PEG 2 6 8 10 10000) ... ... ...
Hexylene glycol 0.6 0.5 0.4
Polyacrylic acid 6 6 5 6 5 5 5
NaOH 37 33 30 28 26 26 25
1 ,2,3-Benzotriazole 6 6 5
Disilcate 6 5 4 4
N,Nbis(carboxylatomethyl) 28 24 24 -L-glutamate (GLDA)
Water Add. Add. Add. Add. Add. Add. Add.
100 100 100 100 100 100 100
An aqueous ready-to-use liquid mild alkaline cleaning solution is formed, wherein 1.0 g of examples El to E7 and VI to V14 are dissolved in 100 ml of deionized water each.
The cleaning performance of the compositions El to E7 compared to VI to V14 was tested in an automatic metal instrument cleaning apparatus Miele G 7836 CD, Program DES- VAR-TD, 55 °C, 10 minutes.
It was surprisingly found, that the cleaning performance of El to E7 are the same of VI to V14. However, El to E7 shows no foam formation at all contrary to VI to V14.
Further, the average weight loss for aluminum test plates after treatment with said ready-to-use liquid mild alkaline cleaning solution obtained from El to E7 compared to VI to V14 is improved.
As used herein, the term "about" refers to variation in the numerical quantity that can occur, for example, through typical measuring and liquid handling procedures used for making concentrates or use solutions in the real world; through inadvertent error in these procedures; through differences in the manufacture, source, or purity of the ingredients used to make the compositions or carry out the methods; and the like. The term "about" also encompasses amounts that differ due to different equilibrium conditions for a composition resulting from a particular initial mixture. Whether or not modified by the term "about", the claims include equivalents to the quantities.
It should be noted that, as used in this specification and the appended claims, the singular forms "a", "an" and "the" include plural referents unless the content clearly dictates otherwise.
Thus, for example, reference to a composition containing "a compound" includes a mixture of two or more compounds. It should also be noted that the term "or" is generally employed in its sense including "and/or" unless the content clearly dictates otherwise. All publications and patent applications in this specification are indicative of the level of ordinary skill in the art to which this invention pertains. The invention has been described to various specific and preferred embodiments and techniques. However, it should be understood that many variations and modifications may be made while remaining within the spirit and scope of the invention.
Claims
1. A mild alkaline solid cleaning composition comprising:
- at least one alkaline source,
- at least one polyethylene glycol, and
- at least one corrosion inhibitor;
wherein the weight-% ratio of the alkaline source to the polyethylene glycol is > 30 : 1; and wherein the weight-% of the components are based on the total weight of the mild alkaline solid cleaning composition.
2. The mild alkaline solid cleaning composition according to claim 1, wherein the
composition comprises at least two corrosion inhibitors, preferably > 16 wt.-% of an sodium disilicate and > 4 wt.-% of an benzotriazole; wherein the weight-% of the components are based on the total weight of the mild alkaline solid cleaning composition.
3. The mild alkaline solid cleaning composition according to claims 1 or 2, comprising:
- about > 10 wt.-% to about < 35 wt.-%, preferably about > 13 wt.-% to about < 24 wt.- %, and more preferred about > 15 wt.-% to about < 20 wt.-%, of at least one alkaline source, preferably sodium hydroxide;
- about > 0.1 wt.-% to about < 1 wt.-%, preferably about > 0.2 wt.-% to about < 0.8 wt- %, further preferred about > 0.3 wt.-% to about < 0.7 wt.-%, and more preferred about > 0.4 w -% to about < 0.6 wt.-%, and most preferred about 0.5 wt.-%, of at least one polyethylene glycol, preferably a polyethylene glycol with an average mol weight in the range of 4.000 to 12.000, and more preferred a polyethylene glycol having an average mol weight of about 8,000; and
- about > 15 wt.-% to about < 40 wt.-%, preferably about > 18 wt.-% to about < 35 wt.- %, further preferred about > 20 wt.-% to about < 28 wt.-%, and more preferred about > 23 wt.-% to about < 25 wt.-%, of at least one corrosion inhibitor, preferably sodium disilicate, and more preferred at least two corrosion inhibitors, preferably a benzotriazol and sodium disilicate;
- a solvent, preferably water, is added add. 100 wt.-%; wherein
the weight-% of the components are based on the total weight of the of the mild alkaline solid cleaning composition.
4. The mild alkaline solid cleaning composition according to claims 1 to 3, wherein the composition comprises at least one alkaline source selected from the group of sodium hydroxide, sodium carbonate, potassium hydroxide, and lithium hydroxide.
5. The mild alkaline solid cleaning composition according to claims 1 to 4, wherein the composition comprises at least one, preferably two, corrosion inhibitors selected from the group comprising silicate, sodium silicate, sodium disilicate, calcium acetate, calcium chloride, calcium gluconate, calcium phosphate, calcium borate, calcium carbonate, calcium citrate, calcium lactate, calcium sulfate, calcium tartrate, benzotriazole, 1,2,3- benzotriazole, and mixtures thereof.
6. The mild alkaline solid cleaning composition according to claims 1 to 5, wherein the composition comprises at least one threshold inhibitor/crystal modifier selected from the group comprising salts of phosphonocarboxylic acids, phosphonates, salts of 1- hydroxyethylidene -1,1,-diphosphonic acid (HEDP), salts of acid substituted polymers, and mixtures thereof, preferably salts of acid substituted polymers of monomers of acrylate, methacrylate, salts of polyitaconic acid, salts of polymaleic acid, and mixtures thereof.
7. The mild alkaline solid cleaning composition according to claims 1 to 6, wherein the composition comprises at least one sequestering agent composition selected from the group of sodium gluconate, pentasodium salt of diethylenetriamine pentaacetic acid, sodium glucoheptonate, salts of ethylene diamine tetraacetic acid, salts of ethylene diamine tetraacetic acid, salts of hydroxy ethyl ethylene diamine triacetic acid, salts of hydroxy ethyl ethylene diamine triacetic acid, salts of nitrilo triacetic acid, salts of nitrilotriacetic acid, diethanolglycine sodium salt, ethanoldiglycine disodium salt, salts of hydroxymonocarboxylic acid compounds, salts of hydroxy dicarboxy lie acid compounds, salts of amine containing carboxylic acids, terasodium N,N-bis(carboxylatomethyl)-L- glutamate (GLDA) and mixtures thereof.
8. The mild alkaline solid cleaning composition according to claims 1 to 7, wherein the composition comprises at least one solvent selected from the group comprising water, alcohols, ethanol, isopropanol, 2 -butoxy ethanol, 1-decanol, benzyl alcohol, glycerin, monoethanolamine, glycols, ethylene glycol, diethylene glycol, propylene glycol, butoxy
diglycol, triethylene glycol, tetraethylene glycol, glycerin, propylene glycol, dipropylene glycol, hexylene glycol, glycol ethers, esters, or combinations thereof. Suitable alcohols include, but are not limited to, ethanol, isopropanol, 2-butoxy ethanol, 1-decanol, benzyl alcohol, glycerin, monoethanolamine, or combinations thereof; preferably the
composition comprises at least two solvents and more preferred the composition comprises water and hexylene glycol.
9. The mild alkaline solid cleaning composition according to claims 1 to 8, comprising:
- about > 10 wt.-% to about < 35 wt.-%, preferably about > 13 wt.-% to about < 24 wt- %, and more preferred about > 15 wt.-% to about < 20 wt.-%, of at least one alkaline source, preferably sodium hydroxide;
- about > 0.1 wt.-% to about < 1 wt.-%, preferably about > 0.2 wt.-% to about < 0.8 wt- %, further preferred about > 0.3 wt.-% to about < 0.7 wt.-%, and more preferred about > 0.4 wt.-% to about < 0.6 wt.-%, and most preferred about 0.5 wt.-%, of at least one polyethylene glycol, preferably a polyethylene glycol with an average mol weight in the range of 4.000 to 12.000, and more preferred a polyethylene glycol having an average mol weight of about 8,000 ; and
- about > 15 wt.-% to about < 40 wt.-%, preferably about > 18 wt.-% to about < 35 wt- %, further preferred about > 20 wt.-% to about < 28 wt.-%, and more preferred about > 23 wt.-% to about < 25 wt.-%, of at least one corrosion inhibitor, preferably sodium disilicate, and more preferred at least two corrosion inhibitors, preferably a benzotriazol and sodium disilicate;
- about > 0.5 wt.-% to about < 15 wt.-%, preferably about > 1 wt.-% to about < 10 wt- %, and more preferred about > 3 wt.-% to about < 5 wt.-% of at least one threshold inhibitor/crystal modifier, preferably the threshold inhibitor/crystal modifier is a salt of a polyacrylic acid;
- about > 5 wt.-% to about < 40 wt.-%, preferably about > 15 wt.-% to about < 30 wt- %, and more preferred about > 20 wt.-% to about < 25 wt.-% of at least one sequestering agent, preferably the sequestering agent is a salt of an amine containing carboxylic acid, and more preferred terasodium N,N-bis(carboxylatomethyl)-L- glutamate (GLDA);
- a solvent, preferably water, is added add. 100 wt.-%; wherein
the weight-% of the components are based on the total weight of the of the mild alkaline solid cleaning composition.
10. A solution of the mild alkaline solid cleaning composition according to claims 1 to 9.
11. The solution of claim 11 , wherein the solution is a concentrated liquid composition or a ready-to-use liquid mild alkaline cleaning solution.
12. The solution of claim 10 or 11, wherein the ratio of the solvent, preferably water, to solid, to provide a concentrated liquid composition, preferably an aqueous solution, of the mild alkaline solid cleaning composition is in the range of from about 200 : 1 to about 10 : 1, preferably about 100 : 1 to about 12 : 1, further preferred about 50 : 1 to about 15 : 1, also preferred about 40 : 1 to about 17 : 1 and in particular preferred about 30 : 1 to about 20 : 1; or
the ratio of the solvent, preferably water, to solid, to provide a ready-to-use liquid mild alkaline cleaning solution, preferably an aqueous solution, of the mild alkaline solid cleaning composition is in the range of from about 60,000 : 1 to about 100 : 1, preferably about 30,000 : 1 to about 300 : 1, further preferred about 10,000 : 1 to about 500 : 1, also preferred about 5,000 : 1 to about 750 : 1 and in particular preferred about 2,500 : 1 to about 1,000 : 1.
13. Use of the solution of claims 10 to 12 to clean hard and soft surfaces, preferably metal and/or plastic articles, metal surfaces and/or plastic surfaces, more preferred metal instruments, plastic instruments, instruments with a plastic surface and/or instruments with a metal surface.
14. Use of the solution of claim 13 to clean hard and soft surfaces, preferably metal and/or plastic articles, metal surfaces and/or plastic surfaces, further preferred metal instruments, plastic instruments, instruments with a plastic surface, instruments with a metal surface and/or surgical instruments, in an automated processing.
15. A cleaning apparatus comprising:
(a) a first container comprising an alkaline solid composition according to claims 1 to 9;
(b) a second container comprising a concentrated liquid composition of the solid
composition according to claim 12 or 14 having a pH of about > 12.5 to about < 13.5, preferably a pH of 13;
(c) optional a third container comprising a day solution of the concentrated liquid composition or a ready to use solution having a pH of about > 9,5 to about < 11,0;
(d) a water feed for conveying water to the first container for forming said solution from water;
(e) a solution line for conveying solution from the first container to the second
container;
(f) optional a third container that is connected with the second container with a solution line for conveying solution from the second container to the third container; and
(g) a use solution line for conveying the use solution from the second container and/or third container to a use solution applicator and/or to the place of use.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL13739990T PL3022280T3 (en) | 2013-07-19 | 2013-07-19 | Mild alkaline solid instrument cleaner |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2013/065351 WO2015007347A1 (en) | 2013-07-19 | 2013-07-19 | Mild alkaline solid instrument cleaner |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP3022280A1 true EP3022280A1 (en) | 2016-05-25 |
| EP3022280B1 EP3022280B1 (en) | 2019-01-02 |
Family
ID=48856617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP13739990.3A Active EP3022280B1 (en) | 2013-07-19 | 2013-07-19 | Mild alkaline solid instrument cleaner |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP3022280B1 (en) |
| PL (1) | PL3022280T3 (en) |
| WO (1) | WO2015007347A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10844325B2 (en) * | 2015-12-22 | 2020-11-24 | Basf Se | Composition for post chemical-mechanical-polishing cleaning |
| CN115418644B (en) * | 2022-10-10 | 2024-03-26 | 湖南金裕环保科技有限公司 | Corrosion inhibitor, preparation method and application thereof in water-based cleaning agent |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0842257B1 (en) * | 1995-07-13 | 2000-12-27 | Benckiser N.V. | Dish washer product in tablet form |
| US5756444A (en) * | 1996-11-01 | 1998-05-26 | The Procter & Gamble Company | Granular laundry detergent compositions which are substantially free of phosphate and aluminosilicate builders |
| DE19758262A1 (en) * | 1997-12-31 | 1999-07-08 | Henkel Kgaa | Granular component containing alkylaminotriazole for use in machine dishwashing detergents (MGSM) and process for its production |
| AU2000260630A1 (en) * | 2000-06-30 | 2002-01-14 | The Procter & Gamble Company | Detergent compositions comprising a cyclodextrin glucanotransferase enzyme |
| DE10313454A1 (en) * | 2003-03-25 | 2004-10-21 | Henkel Kgaa | Detergents or cleaning agents |
| US20080096784A1 (en) * | 2006-05-15 | 2008-04-24 | Voco Gmbh | Composition for Cleaning Dental Instruments and Process |
| GB0616444D0 (en) * | 2006-08-18 | 2006-09-27 | Reckitt Benckiser Nv | Detergent composition |
| EP2625257B2 (en) * | 2010-10-08 | 2022-11-02 | Ecolab USA Inc. | Cleaning efficacy of metal-safe solid for automated instrument processing |
-
2013
- 2013-07-19 WO PCT/EP2013/065351 patent/WO2015007347A1/en active Application Filing
- 2013-07-19 EP EP13739990.3A patent/EP3022280B1/en active Active
- 2013-07-19 PL PL13739990T patent/PL3022280T3/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2015007347A1 (en) | 2015-01-22 |
| PL3022280T3 (en) | 2019-06-28 |
| EP3022280B1 (en) | 2019-01-02 |
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