EP3010929A4 - Procédés universels de profilage de la méthylation - Google Patents

Procédés universels de profilage de la méthylation Download PDF

Info

Publication number
EP3010929A4
EP3010929A4 EP14812900.0A EP14812900A EP3010929A4 EP 3010929 A4 EP3010929 A4 EP 3010929A4 EP 14812900 A EP14812900 A EP 14812900A EP 3010929 A4 EP3010929 A4 EP 3010929A4
Authority
EP
European Patent Office
Prior art keywords
profiling methods
methylation profiling
universal
universal methylation
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14812900.0A
Other languages
German (de)
English (en)
Other versions
EP3010929A1 (fr
Inventor
Timothy H. Bestor
Jingyue Ju
Xiaoxu Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Columbia University in the City of New York
Original Assignee
Columbia University in the City of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Columbia University in the City of New York filed Critical Columbia University in the City of New York
Publication of EP3010929A1 publication Critical patent/EP3010929A1/fr
Publication of EP3010929A4 publication Critical patent/EP3010929A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/167—Purine radicals with ribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP14812900.0A 2013-06-17 2014-06-16 Procédés universels de profilage de la méthylation Withdrawn EP3010929A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361836060P 2013-06-17 2013-06-17
PCT/US2014/042567 WO2014204861A1 (fr) 2013-06-17 2014-06-16 Procédés universels de profilage de la méthylation

Publications (2)

Publication Number Publication Date
EP3010929A1 EP3010929A1 (fr) 2016-04-27
EP3010929A4 true EP3010929A4 (fr) 2017-02-22

Family

ID=52105162

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14812900.0A Withdrawn EP3010929A4 (fr) 2013-06-17 2014-06-16 Procédés universels de profilage de la méthylation

Country Status (3)

Country Link
EP (1) EP3010929A4 (fr)
CN (1) CN105408342A (fr)
WO (1) WO2014204861A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10337049B2 (en) * 2013-06-17 2019-07-02 The Trustees Of Columbia University In The City Of New York Universal methylation profiling methods

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090018101A1 (en) * 2005-04-14 2009-01-15 Rwth Aachen S-adenosyl-l-methionine analogs with extended activated groups for transfer by methyltransferases
US20110177508A1 (en) * 2008-07-22 2011-07-21 Bestor Timothy H Universal methylation profiling methods

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3726821A (en) * 1968-12-23 1973-04-10 Dow Chemical Co Wash-resistant antistatic coating compositions
US4267171A (en) * 1979-07-02 1981-05-12 The Regents Of The University Of California C-5 Substituted cytosine nucleosides
GB9602025D0 (en) * 1996-02-01 1996-04-03 Amersham Int Plc Nucleoside analogues
US20080103053A1 (en) * 2005-11-22 2008-05-01 Helicos Biosciences Corporation Methods and compositions for sequencing a nucleic acid
WO2009078876A1 (fr) * 2007-12-18 2009-06-25 Bellbrook Labs, Llc Procédé de dosage pour des réactions de transfert de groupes
TW200944489A (en) * 2008-01-30 2009-11-01 Dow Corning Toray Co Ltd Silicon-containing particle, process for producing the same, organic-polymer composition, ceramic, and process for producing the same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090018101A1 (en) * 2005-04-14 2009-01-15 Rwth Aachen S-adenosyl-l-methionine analogs with extended activated groups for transfer by methyltransferases
US20110177508A1 (en) * 2008-07-22 2011-07-21 Bestor Timothy H Universal methylation profiling methods

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HARALD STECHER ET AL: "Biocatalytic Friedel-Crafts Alkylation Using Non-natural Cofactors", ANGEWANDTE CHEMIE INTERNATIONAL EDITION, vol. 48, no. 50, 7 December 2009 (2009-12-07), pages 9546 - 9548, XP055048957, ISSN: 1433-7851, DOI: 10.1002/anie.200905095 *
See also references of WO2014204861A1 *

Also Published As

Publication number Publication date
CN105408342A (zh) 2016-03-16
EP3010929A1 (fr) 2016-04-27
WO2014204861A1 (fr) 2014-12-24

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RIC1 Information provided on ipc code assigned before grant

Ipc: C07H 1/00 20060101ALI20161017BHEP

Ipc: C07H 19/167 20060101AFI20161017BHEP

Ipc: C07H 21/04 20060101ALI20161017BHEP

Ipc: C12Q 1/68 20060101ALI20161017BHEP

A4 Supplementary search report drawn up and despatched

Effective date: 20170124

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Ipc: C07H 19/167 20060101AFI20170118BHEP

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Effective date: 20170822