EP3004389A4 - Kits and methods for detecting drug-induced deafness susceptibility - Google Patents

Kits and methods for detecting drug-induced deafness susceptibility Download PDF

Info

Publication number
EP3004389A4
EP3004389A4 EP14804634.5A EP14804634A EP3004389A4 EP 3004389 A4 EP3004389 A4 EP 3004389A4 EP 14804634 A EP14804634 A EP 14804634A EP 3004389 A4 EP3004389 A4 EP 3004389A4
Authority
EP
European Patent Office
Prior art keywords
kits
methods
detecting drug
induced deafness
susceptibility
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP14804634.5A
Other languages
German (de)
French (fr)
Other versions
EP3004389A1 (en
Inventor
Yanling Kong
Guangxin Xiang
Xiaogang Zhang
Shujian LIANG
Wanli Xing
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tsinghua University
CapitalBio Technology Co Ltd
Original Assignee
Tsinghua University
CapitalBio Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tsinghua University, CapitalBio Corp filed Critical Tsinghua University
Publication of EP3004389A1 publication Critical patent/EP3004389A1/en
Publication of EP3004389A4 publication Critical patent/EP3004389A4/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP14804634.5A 2013-05-30 2014-05-30 Kits and methods for detecting drug-induced deafness susceptibility Ceased EP3004389A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2013102085599A CN103276082A (en) 2013-05-30 2013-05-30 Kit for detecting mutation sites of drug-induced deafness susceptible gene
PCT/CN2014/000548 WO2014190762A1 (en) 2013-05-30 2014-05-30 Kits and methods for detecting drug-induced deafness susceptibility

Publications (2)

Publication Number Publication Date
EP3004389A1 EP3004389A1 (en) 2016-04-13
EP3004389A4 true EP3004389A4 (en) 2017-02-01

Family

ID=49058697

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14804634.5A Ceased EP3004389A4 (en) 2013-05-30 2014-05-30 Kits and methods for detecting drug-induced deafness susceptibility

Country Status (4)

Country Link
EP (1) EP3004389A4 (en)
CN (1) CN103276082A (en)
HK (1) HK1222683A1 (en)
WO (1) WO2014190762A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103451302A (en) * 2013-09-11 2013-12-18 步迅 Deafness susceptible gene mitochondrion 12SrDNA 1555A>G and 1494C>T mutant ratio detection kit
CN103436625B (en) * 2013-09-11 2016-03-30 步迅 6 deaf sick susceptibility loci somatotype/mutant proportion detection kit
CN105506120B (en) * 2016-01-05 2019-10-18 石玉玲 The multiple Taqman fluorescence detection reagent kit of mitochondrial mutations deafness
CN106399553B (en) * 2016-11-09 2020-10-23 上海添音生物科技有限公司 Human mitochondrial whole genome high-throughput sequencing method based on multiple PCR
CN107287303A (en) * 2017-06-28 2017-10-24 浙江大学 The fluorescent quantificationally PCR detecting kit of chondriosome deafness A1555G mutation and its application
CN112538524A (en) * 2019-12-31 2021-03-23 北京毅新博创生物科技有限公司 Detection product for detecting gene SNP related to deafness
CN112538523A (en) * 2019-12-31 2021-03-23 北京毅新博创生物科技有限公司 Primer group for detecting gene SNP (Single nucleotide polymorphism) related to deafness

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101768637A (en) * 2009-11-20 2010-07-07 温州医学院 Kit for simultaneously detecting mutations in mitochondria DNA A1555G and C1494T and using method thereof
CN102154481A (en) * 2011-02-11 2011-08-17 智海生物工程（北京）有限公司 Method for detecting mitochondrial mutations and kit thereof
CN102787169A (en) * 2012-08-22 2012-11-21 郭丽敏 Mixed liquor, kit and detection system for detecting A1555G and C1494T mutation of mitochondria DNA (deoxyribonucleic acid)
CN103451302A (en) * 2013-09-11 2013-12-18 步迅 Deafness susceptible gene mitochondrion 12SrDNA 1555A>G and 1494C>T mutant ratio detection kit

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060288444A1 (en) * 2004-08-13 2006-12-21 Mccarroll Robert Soybean polymorphisms and methods of genotyping
CN1987463B (en) * 2006-12-26 2015-04-01 金政策 Real-time quantitative Taq ManMGB probe kit
CN101684497B (en) * 2008-09-23 2011-09-28 中国人民解放军总医院 Deafness susceptibility gene screen test kit

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101768637A (en) * 2009-11-20 2010-07-07 温州医学院 Kit for simultaneously detecting mutations in mitochondria DNA A1555G and C1494T and using method thereof
CN102154481A (en) * 2011-02-11 2011-08-17 智海生物工程（北京）有限公司 Method for detecting mitochondrial mutations and kit thereof
CN102787169A (en) * 2012-08-22 2012-11-21 郭丽敏 Mixed liquor, kit and detection system for detecting A1555G and C1494T mutation of mitochondria DNA (deoxyribonucleic acid)
CN103451302A (en) * 2013-09-11 2013-12-18 步迅 Deafness susceptible gene mitochondrion 12SrDNA 1555A>G and 1494C>T mutant ratio detection kit

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
HUANG SHASHA ET AL: "Rapid identification of aminoglycoside-induced deafness gene mutations using multiplex real-time polymerase chain reaction", INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, vol. 79, no. 7, 2015, pages 1067 - 1072, XP029185034, ISSN: 0165-5876, DOI: 10.1016/J.IJPORL.2015.04.028 *
See also references of WO2014190762A1 *
ZHENG L ET AL: "A novel method of detecting mitochondrial m.1494C>T and m.1555A>G mutations in a single PCR reaction using base-quenched probe", CLINICA CHIMICA ACTA, ELSEVIER BV, AMSTERDAM, NL, vol. 411, no. 23-24, 14 December 2010 (2010-12-14), pages 2114 - 2116, XP027406802, ISSN: 0009-8981, [retrieved on 20101007] *

Also Published As

Publication number Publication date
WO2014190762A1 (en) 2014-12-04
HK1222683A1 (en) 2017-07-07
CN103276082A (en) 2013-09-04
EP3004389A1 (en) 2016-04-13

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