EP2996471A4 - Aminoglycoside and azole compositions and methods - Google Patents

Aminoglycoside and azole compositions and methods

Info

Publication number
EP2996471A4
EP2996471A4 EP14797052.9A EP14797052A EP2996471A4 EP 2996471 A4 EP2996471 A4 EP 2996471A4 EP 14797052 A EP14797052 A EP 14797052A EP 2996471 A4 EP2996471 A4 EP 2996471A4
Authority
EP
European Patent Office
Prior art keywords
aminoglycoside
methods
azole compositions
azole
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14797052.9A
Other languages
German (de)
French (fr)
Other versions
EP2996471A2 (en
Inventor
Jon Takemoto
Cheng-Wei Chang
Sanjib Shrestha
Michelle Grilley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Utah State University USU
Original Assignee
Utah State University USU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Utah State University USU filed Critical Utah State University USU
Publication of EP2996471A2 publication Critical patent/EP2996471A2/en
Publication of EP2996471A4 publication Critical patent/EP2996471A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
EP14797052.9A 2013-05-17 2014-05-19 Aminoglycoside and azole compositions and methods Withdrawn EP2996471A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361824847P 2013-05-17 2013-05-17
PCT/US2014/038649 WO2014186804A2 (en) 2013-05-17 2014-05-19 Aminoglycoside and azole compositions and methods

Publications (2)

Publication Number Publication Date
EP2996471A2 EP2996471A2 (en) 2016-03-23
EP2996471A4 true EP2996471A4 (en) 2016-12-28

Family

ID=51899031

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14797052.9A Withdrawn EP2996471A4 (en) 2013-05-17 2014-05-19 Aminoglycoside and azole compositions and methods

Country Status (3)

Country Link
EP (1) EP2996471A4 (en)
JP (1) JP2016520086A (en)
WO (1) WO2014186804A2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0064830A2 (en) * 1981-04-29 1982-11-17 Pfizer Limited Pharmaceutical compositions for treating nail infections

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL340606A1 (en) * 1997-10-22 2001-02-12 Jens Ponikau Methods of and materials for treating and preventing mucositis
WO2010037179A1 (en) * 2008-10-03 2010-04-08 Glycan Biosciences Pty Ltd Anionic conjugates of glycosylated bacterial metabolite
EP2651959B1 (en) * 2010-12-14 2018-02-07 Utah State University Aminoglycosides:synthesis and use as antifungals

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0064830A2 (en) * 1981-04-29 1982-11-17 Pfizer Limited Pharmaceutical compositions for treating nail infections

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KATHIRAVAN MUTHU K ET AL: "The biology and chemistry of antifungal agents: A review", BIOORGANIC & MEDICINAL CHEMISTRY, vol. 20, no. 19, 9 May 2012 (2012-05-09), pages 5678 - 5698, XP028939845, ISSN: 0968-0896, DOI: 10.1016/J.BMC.2012.04.045 *
SHRESTHA S ET AL: "Synergistic Activities of Azoles and K20 against Azole-resistant Candida albicans 10231", ABSTRACTS OF THE GENERAL MEETING OF THE AMERICAN SOCIETY FOR MICROBIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 113, 18 May 2013 (2013-05-18), XP009192428, ISSN: 1060-2011 *

Also Published As

Publication number Publication date
WO2014186804A3 (en) 2015-01-08
JP2016520086A (en) 2016-07-11
EP2996471A2 (en) 2016-03-23
WO2014186804A2 (en) 2014-11-20

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RIN1 Information on inventor provided before grant (corrected)

Inventor name: TAKEMOTO, JON

Inventor name: CHANG, CHENG-WEI

Inventor name: GRILLEY, MICHELLE

Inventor name: SHRESTHA, SANJIB

DAX Request for extension of the european patent (deleted)
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Effective date: 20161125

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Ipc: A61K 31/4174 20060101ALI20161121BHEP

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Ipc: A61K 31/506 20060101ALI20161121BHEP

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