EP2986294A4 - Verfahren zur schmerzbehandlung - Google Patents

Verfahren zur schmerzbehandlung

Info

Publication number
EP2986294A4
EP2986294A4 EP14785169.5A EP14785169A EP2986294A4 EP 2986294 A4 EP2986294 A4 EP 2986294A4 EP 14785169 A EP14785169 A EP 14785169A EP 2986294 A4 EP2986294 A4 EP 2986294A4
Authority
EP
European Patent Office
Prior art keywords
pain
compounds
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14785169.5A
Other languages
English (en)
French (fr)
Other versions
EP2986294A1 (de
Inventor
Anthony Marfat
Peter Cornelius
Panayiotis Zagouras
Frederick Raymond Nelson
Anton Franz Joseph Fliri
Robert VOLKMANN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BIOPHARMA WORKS
Original Assignee
Biopharma Works
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biopharma Works filed Critical Biopharma Works
Publication of EP2986294A1 publication Critical patent/EP2986294A1/de
Publication of EP2986294A4 publication Critical patent/EP2986294A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • C07D489/04—Salts; Organic complexes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP14785169.5A 2013-04-17 2014-04-16 Verfahren zur schmerzbehandlung Withdrawn EP2986294A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361813143P 2013-04-17 2013-04-17
PCT/US2014/034398 WO2014172478A1 (en) 2013-04-17 2014-04-16 Compounds for treatment of pain

Publications (2)

Publication Number Publication Date
EP2986294A1 EP2986294A1 (de) 2016-02-24
EP2986294A4 true EP2986294A4 (de) 2016-11-16

Family

ID=51731831

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14785169.5A Withdrawn EP2986294A4 (de) 2013-04-17 2014-04-16 Verfahren zur schmerzbehandlung

Country Status (3)

Country Link
US (2) US10072018B2 (de)
EP (1) EP2986294A4 (de)
WO (1) WO2014172478A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014172482A1 (en) * 2013-04-17 2014-10-23 Robert Alfred Volkmann Compounds for treatment of pain
US9969746B2 (en) 2013-12-05 2018-05-15 The University Of Bath Opioid compounds and their uses
US11793880B2 (en) 2015-12-04 2023-10-24 Seagen Inc. Conjugates of quaternized tubulysin compounds
TWI814699B (zh) 2015-12-04 2023-09-11 美商思進公司 四級胺化妥布賴森(tubulysin)化合物之結合物

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001037785A2 (en) * 1999-11-29 2001-05-31 Adolor Corporation Novel methods and compositions involving opioids and antagonists thereof
WO2008101202A1 (en) * 2007-02-16 2008-08-21 Pharmacofore, Inc. N-17-alkylated prodrugs of opioids
WO2014172482A1 (en) * 2013-04-17 2014-10-23 Robert Alfred Volkmann Compounds for treatment of pain

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT7920398A0 (it) 1979-02-21 1979-02-21 Resfar Srl Derivato ad attivita' analgesica antiinfiammatoria potenziata eprocedimento per la sua preparazione.
US20070060500A1 (en) * 2000-08-22 2007-03-15 New River Pharmaceuticals Inc. Pharmaceutical compositions for prevention of overdose or abuse
WO2004089925A1 (en) 2003-04-03 2004-10-21 Semafore Pharmaceuticals, Inc. Pi-3 kinase inhibitor prodrugs
JP2009533443A (ja) * 2006-04-10 2009-09-17 シャイア エルエルシー 一置換及び二置換のオキシコドン化合物及び組成物
EP2121029A2 (de) * 2006-12-05 2009-11-25 Neurogesx, Inc. Prodrugs und verfahren zu ihrer herstellung und verwendung
BRPI1011505A2 (pt) 2009-03-11 2016-03-22 Auckland Uniservices Ltd formas de pró-drogas de inibidores de quinase e sua aplicação em terapia
WO2011084846A1 (en) * 2010-01-07 2011-07-14 Alkermes, Inc. Quaternary ammonium salt prodrugs

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001037785A2 (en) * 1999-11-29 2001-05-31 Adolor Corporation Novel methods and compositions involving opioids and antagonists thereof
WO2008101202A1 (en) * 2007-02-16 2008-08-21 Pharmacofore, Inc. N-17-alkylated prodrugs of opioids
WO2014172482A1 (en) * 2013-04-17 2014-10-23 Robert Alfred Volkmann Compounds for treatment of pain

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2014172478A1 *

Also Published As

Publication number Publication date
US20190002473A1 (en) 2019-01-03
WO2014172478A1 (en) 2014-10-23
EP2986294A1 (de) 2016-02-24
US20160083393A1 (en) 2016-03-24
US10072018B2 (en) 2018-09-11

Similar Documents

Publication Publication Date Title
IL241232A0 (en) Cancer treatment agents
IL243976A0 (en) kdm1a inhibitors for disease treatment
EP2968348A4 (de) Verbindungen zur behandlung von krebs
EP2968321A4 (de) Verbindungen zur behandlung von fibroseerkrankungen
EP2977014A4 (de) Katheter zur behandlung von sinusitis
HK1219737A1 (zh) 用於治療癌症的新化合物
IL243637B (en) PPAR-sparing compounds for the treatment of metabolic diseases
EP2986294A4 (de) Verfahren zur schmerzbehandlung
IL241096A0 (en) Treatment methods
EP3104869A4 (de) Schmerzbehandlung
GB201607581D0 (en) Treatment of cancer
EP2958572A4 (de) Behandlung von hyperhidrose
GB201308466D0 (en) Improved process for treatment of minewater
EP2948129A4 (de) Therapeutische verbindungen
HK1232118A1 (zh) 癌症的治療
GB201314286D0 (en) Therapeutic Compounds
EP2986295A4 (de) Verfahren zur schmerzbehandlung
IL244620A0 (en) A drug combination including laquinimod for the treatment of multiple sclerosis
PL3016948T3 (pl) 2-acyloaminotiazole do leczenia nowotworów
AU2013905080A0 (en) Treatment of Pain
GB201321628D0 (en) Treatment of disease
GB201322778D0 (en) Method of treatment
AP2015008905A0 (en) Novel compounds for the treatment of cancer
GB201314882D0 (en) Method of treatment
GB201322347D0 (en) Treatment of cancer

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20151102

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: BIOPHARMA WORKS

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20161014

RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 25/04 20060101ALI20161010BHEP

Ipc: A61K 31/4748 20060101AFI20161010BHEP

Ipc: C07D 489/02 20060101ALI20161010BHEP

17Q First examination report despatched

Effective date: 20171207

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20180619