EP2973135A4 - Assays and methods for selecting a treatment regimen for a subject with depression - Google Patents

Assays and methods for selecting a treatment regimen for a subject with depression

Info

Publication number
EP2973135A4
EP2973135A4 EP14778792.3A EP14778792A EP2973135A4 EP 2973135 A4 EP2973135 A4 EP 2973135A4 EP 14778792 A EP14778792 A EP 14778792A EP 2973135 A4 EP2973135 A4 EP 2973135A4
Authority
EP
European Patent Office
Prior art keywords
assays
depression
selecting
subject
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14778792.3A
Other languages
German (de)
French (fr)
Other versions
EP2973135A1 (en
Inventor
Maurizio Fava
George Papakostas
Jr Harold O Koch
David Kronlage
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alfasigma SpA
Original Assignee
Nestec SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/796,362 external-priority patent/US9546401B2/en
Application filed by Nestec SA filed Critical Nestec SA
Publication of EP2973135A1 publication Critical patent/EP2973135A1/en
Publication of EP2973135A4 publication Critical patent/EP2973135A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP14778792.3A 2013-03-12 2014-03-11 Assays and methods for selecting a treatment regimen for a subject with depression Withdrawn EP2973135A4 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361777650P 2013-03-12 2013-03-12
US13/796,362 US9546401B2 (en) 2011-11-14 2013-03-12 Assays and methods for selecting a treatment regimen for a subject with depression
US201361914338P 2013-12-10 2013-12-10
PCT/US2014/023695 WO2014164882A1 (en) 2013-03-12 2014-03-11 Assays and methods for selecting a treatment regimen for a subject with depression

Publications (2)

Publication Number Publication Date
EP2973135A1 EP2973135A1 (en) 2016-01-20
EP2973135A4 true EP2973135A4 (en) 2016-11-16

Family

ID=51658998

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14778792.3A Withdrawn EP2973135A4 (en) 2013-03-12 2014-03-11 Assays and methods for selecting a treatment regimen for a subject with depression

Country Status (12)

Country Link
EP (1) EP2973135A4 (en)
JP (1) JP2016518816A (en)
KR (1) KR20150131147A (en)
CN (1) CN105518685A (en)
AU (1) AU2014248949A1 (en)
BR (1) BR112015022820A8 (en)
CA (1) CA2904418A1 (en)
IL (1) IL241156A0 (en)
MX (1) MX2015012520A (en)
RU (1) RU2015143177A (en)
TW (1) TW201437635A (en)
WO (1) WO2014164882A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2855706A4 (en) * 2012-06-01 2016-06-08 Brc Operations Pty Ltd Biomakers for treatment outcomes
US10881674B2 (en) 2014-12-08 2021-01-05 Glycom A/S Synthetic composition for treating metabolic disorders
US10987368B2 (en) 2014-12-08 2021-04-27 Glycom A/S Synthetic composition for preventing or treating CVD
US10835544B2 (en) 2014-12-08 2020-11-17 Glycom A/S Synthetic composition for regulating satiety
CN107106584A (en) 2014-12-08 2017-08-29 格礼卡姆股份公司 Synthetic composition for treating dysbolism
WO2016135707A1 (en) * 2015-02-27 2016-09-01 Nestec S.A. Diagnosis of major depressive disorder, mild cognitive impairment, and alzheimer's disease and other neurologic and psychiatric disorders
US10780103B2 (en) 2015-10-28 2020-09-22 Glycom A/S Synthetic composition and method for modulating emotion and mood disorders
PL3368046T3 (en) 2015-10-28 2022-11-28 Glycom A/S Synthetic composition and method for modulating brain function and behaviour
KR101911339B1 (en) * 2017-07-17 2018-10-25 고려대학교 산학협력단 Methylation rate of catecholamine-O-methyl transferase gene for providing information about diagnosis of major depressive disorder
CN112423887B (en) * 2018-07-12 2024-06-07 韩国生命工学研究院 Substrate for nucleic acid amplification and method for producing same
CN109234383A (en) * 2018-11-07 2019-01-18 上海康黎医学检验所有限公司 Kit relevant to resisting mental disease medicine, target gene and its preparation, SNP marker, SNP identification and application
CN109966498A (en) * 2019-03-25 2019-07-05 北京坤秋健康科技有限公司 A kind of medical composition and its use of depression
CN111500709A (en) * 2020-05-12 2020-08-07 珠海横琴润孚创新科技有限公司 Metabolic disease gene detection and clinical depth data analysis method
KR102570458B1 (en) * 2021-01-21 2023-08-24 전남대학교산학협력단 Asessment methods and diagnostic kit for depressive disorders in women using genetic biomarkers
JP7432190B2 (en) 2021-03-01 2024-02-16 勝彦 山▲崎▼ Data acquisition methods and kits for identifying patients with antidepressant-resistant major depression
CN116103385A (en) * 2021-11-11 2023-05-12 中国科学院深圳理工大学(筹) Gene diagnosis kit and system for predicting response of depressive disorder patient to treatment
WO2023237305A1 (en) 2022-06-09 2023-12-14 Société des Produits Nestlé S.A. Nutritional composition comprising gos and hmos

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120115147A1 (en) * 2010-11-05 2012-05-10 Lombard Jay L Neuropsychiatric test reports
WO2012128799A2 (en) * 2010-12-03 2012-09-27 General Hospital Corporation, The Treating schizophrenia
WO2013074676A2 (en) * 2011-11-14 2013-05-23 The General Hospital Corporation Assays and methods for selecting a treatment regimen for a subject with depression

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060216737A1 (en) * 2005-03-10 2006-09-28 John Bodeau Methods for multiplex amplification
US20100304391A1 (en) * 2009-05-29 2010-12-02 Lombard Jay L Methods for assessment and treatment of depression via utilization of single nucleotide polymorphisms analysis
AU2010300475A1 (en) * 2009-09-30 2012-05-03 The Regents Of The University Of California Cofactors and methods for use for individuals

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120115147A1 (en) * 2010-11-05 2012-05-10 Lombard Jay L Neuropsychiatric test reports
WO2012128799A2 (en) * 2010-12-03 2012-09-27 General Hospital Corporation, The Treating schizophrenia
WO2013074676A2 (en) * 2011-11-14 2013-05-23 The General Hospital Corporation Assays and methods for selecting a treatment regimen for a subject with depression

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JAIN ET AL.: "Personalized Therapy of Adjunctive L-methylfolate to Selective Serotonin Reuptake Inhibitor-Resistant Major Depressive Disorder.'", POSTER PRESENTATION AT THE COLLEGE OF PSYCHIATRIC AND NEUROLOGIC PHARMACISTS ANNUAL MEETING, [ONLINE], 2 May 2012 (2012-05-02), XP055287748, Retrieved from the Internet <URL:http://www.psychiatrictimes.com/all/editorial/psychiatrictimes/pdfs/jainCPNPBiomarker.pdf> [retrieved on 20160712] *
See also references of WO2014164882A1 *
TARO KISHI ET AL: "GTP cyclohydrolase 1 gene haplotypes as predictors of SSRI response in Japanese patients with major depressive disorder", JOURNAL OF AFFECTIVE DISORDERS., vol. 142, no. 1-3, 1 December 2012 (2012-12-01), NL, pages 315 - 322, XP055307006, ISSN: 0165-0327, DOI: 10.1016/j.jad.2012.05.004 *

Also Published As

Publication number Publication date
KR20150131147A (en) 2015-11-24
IL241156A0 (en) 2015-11-30
MX2015012520A (en) 2016-01-12
CN105518685A (en) 2016-04-20
TW201437635A (en) 2014-10-01
CA2904418A1 (en) 2014-10-09
AU2014248949A1 (en) 2015-09-10
EP2973135A1 (en) 2016-01-20
JP2016518816A (en) 2016-06-30
BR112015022820A2 (en) 2017-07-18
WO2014164882A1 (en) 2014-10-09
BR112015022820A8 (en) 2019-11-26
RU2015143177A (en) 2017-04-18

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