EP2956170A4 - Composition and method for diagnosis and immunotherapy of lung cancer - Google Patents

Composition and method for diagnosis and immunotherapy of lung cancer

Info

Publication number
EP2956170A4
EP2956170A4 EP14751009.3A EP14751009A EP2956170A4 EP 2956170 A4 EP2956170 A4 EP 2956170A4 EP 14751009 A EP14751009 A EP 14751009A EP 2956170 A4 EP2956170 A4 EP 2956170A4
Authority
EP
European Patent Office
Prior art keywords
immunotherapy
diagnosis
composition
lung cancer
lung
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14751009.3A
Other languages
German (de)
French (fr)
Other versions
EP2956170A1 (en
Inventor
Maurizio Chiriva-Internati
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Texas A&M University System
Texas Tech University System
Original Assignee
Texas A&M University System
Texas Tech University System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Texas A&M University System, Texas Tech University System filed Critical Texas A&M University System
Priority claimed from PCT/US2014/016032 external-priority patent/WO2014127006A1/en
Publication of EP2956170A1 publication Critical patent/EP2956170A1/en
Publication of EP2956170A4 publication Critical patent/EP2956170A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57423—Specifically defined cancers of lung
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4615—Dendritic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
    • A61K39/4622—Antigen presenting cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3023—Lung
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
EP14751009.3A 2013-02-12 2014-02-12 Composition and method for diagnosis and immunotherapy of lung cancer Withdrawn EP2956170A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361763629P 2013-02-12 2013-02-12
PCT/US2014/016032 WO2014127006A1 (en) 2013-02-12 2014-02-12 Composition and method for diagnosis and immunotherapy of lung cancer

Publications (2)

Publication Number Publication Date
EP2956170A1 EP2956170A1 (en) 2015-12-23
EP2956170A4 true EP2956170A4 (en) 2016-06-22

Family

ID=54540266

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14751009.3A Withdrawn EP2956170A4 (en) 2013-02-12 2014-02-12 Composition and method for diagnosis and immunotherapy of lung cancer

Country Status (1)

Country Link
EP (1) EP2956170A4 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020168662A1 (en) * 2001-02-26 2002-11-14 Lim Seah H. Sperm protein 17 for the diagnosis and treatment of cancer

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020168662A1 (en) * 2001-02-26 2002-11-14 Lim Seah H. Sperm protein 17 for the diagnosis and treatment of cancer

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
CHIRIVA-INTERNATI MAURIZIO ET AL: "Cancer Testis Antigens: A Novel Target in Lung Cancer", INTERNATIONAL REVIEWS OF IMMUNOLOGY, vol. 31, no. 5, October 2012 (2012-10-01), pages 321 - 343, XP009171946 *
CHIRIVA-INTERNATI MAURIZIO: "Sperm protein 17: clinical relevance of a cancer/testis antigen, from contraception to cancer immunotherapy, and beyond", INTERNATIONAL REVIEWS OF IMMUNOLOGY, HARWOOD ACADEMIC PUBLISHERS, LONDON, GB, vol. 30, no. 2-3, 1 April 2011 (2011-04-01), pages 138 - 149, XP008178553, ISSN: 0883-0185, [retrieved on 20110510], DOI: 10.3109/08830185.2011.569903 *
DE JONG ANN ET AL: "Characterization of sperm protein 17 in human somatic and neoplastic tissue.", CANCER LETTERS, vol. 186, no. 2, 5 December 2002 (2002-12-05), pages 201 - 209, XP002753185, ISSN: 0304-3835 *
F. GRIZZI ET AL: "Sperm Protein 17 Is Expressed in Human Somatic Ciliated Epithelia", JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY, vol. 52, no. 4, 1 April 2004 (2004-04-01), US, pages 549 - 554, XP055239279, ISSN: 0022-1554, DOI: 10.1177/002215540405200414 *
GJERSTORFF M F ET AL: "Limited SP17 expression within tumors diminishes its therapeutic potential", TISSUE ANTIGENS, vol. 80, no. 6, December 2012 (2012-12-01), pages 523 - 527, XP002753184 *
MAURIZIO CHIRIVA ET AL: "Identification of new cancer/testis antigens in non-small cell lung cancer - Meeting Abstract", vol. 186, 1 January 2011 (2011-01-01), pages 1, XP008177630, ISSN: 0022-1767, Retrieved from the Internet <URL:http://www.jimmunol.org/cgi/content/meeting_abstract/186/1_MeetingAbstracts/165.16> *
MORTEN F GJERSTORFF ET AL: "Analysis of GAGE, NY-ESO-1 and SP17 cancer/testis antigen expression in early stage non-small cell lung carcinoma", BMC CANCER, BIOMED CENTRAL, LONDON, GB, vol. 13, no. 1, 466, 8 October 2013 (2013-10-08), pages 1 - 6, XP021163559, ISSN: 1471-2407, DOI: 10.1186/1471-2407-13-466 *
See also references of WO2014127006A1 *
SHAN QIANG ET AL: "A cancer/testis antigen microarray to screen autoantibody biomarkers of non-small cell lung cancer", CANCER LETTERS, vol. 328, no. 1, January 2013 (2013-01-01), pages 160 - 167, XP055099771 *

Also Published As

Publication number Publication date
EP2956170A1 (en) 2015-12-23

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