EP2928297A1 - Use of substituted 1-(aryl ethynyl)-, 1-(heteroaryl ethynyl)-, 1-(heterocyclyl ethynyl)- and 1-(cyloalkenyl ethynyl)-bicycloalkanols as active agents against abiotic plant stress - Google Patents

Use of substituted 1-(aryl ethynyl)-, 1-(heteroaryl ethynyl)-, 1-(heterocyclyl ethynyl)- and 1-(cyloalkenyl ethynyl)-bicycloalkanols as active agents against abiotic plant stress

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Publication number
EP2928297A1
EP2928297A1 EP13799047.9A EP13799047A EP2928297A1 EP 2928297 A1 EP2928297 A1 EP 2928297A1 EP 13799047 A EP13799047 A EP 13799047A EP 2928297 A1 EP2928297 A1 EP 2928297A1
Authority
EP
European Patent Office
Prior art keywords
alkyl
alkoxy
aryl
alkoxycarbonyl
alkylaminocarbonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP13799047.9A
Other languages
German (de)
French (fr)
Inventor
Jens Frackenpohl
Thomas Müller
Jan Dittgen
Dirk Schmutzler
Juan Pedro RUIZ-SANTAELLA MORENO
Martin Jeffrey Hills
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer CropScience AG
Original Assignee
Bayer CropScience AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer CropScience AG filed Critical Bayer CropScience AG
Priority to EP13799047.9A priority Critical patent/EP2928297A1/en
Publication of EP2928297A1 publication Critical patent/EP2928297A1/en
Withdrawn legal-status Critical Current

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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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Definitions

  • sucrose synthase and proline transporters are involved here (Hasegawa et al., 2000, Annu Rev Plant Physiol Plant Mol Biol 51: 463-499).
  • the stress control of plants against cold and Dryness partly uses the same molecular mechanisms.
  • LSA proteins Late Embryogenesis Abundant Proteins
  • These are chaperones that stabilize vesicles, proteins and membrane structures in stressed plants (Bray, 1993, Plant Physiol 103: 1035-1040).
  • induction of aldehyde dehydrogenases which detoxify the reactive oxygen species (ROS) produced by oxidative stress, is often used (Kirch et al., 2005, Plant Mol Biol 57: 315-332).
  • ROS reactive oxygen species
  • HSF Heat Shock Factors
  • HSP Heat Shock Proteins
  • Substances or their stable synthetic derivatives and derived structures are also effective in external application to plants or seed dressing and activate defense reactions that result in an increased stress or pathogen tolerance of the plant [Sembdner, and Parthier, 1993, Ann. Rev. Plant Physiol. Plant Mol. Biol. 44: 569-589]. It is also known that chemical substances can increase the tolerance of plants to abiotic stress. Such substances are applied either by seed dressing, by foliar spraying or by soil treatment. Thus, an increase in the abioti stress tolerance of crops by treatment with systemic acquired resistance (SAR) or elicitors
  • SAR systemic acquired resistance
  • PA P poly-ADP-ribose polymerases
  • PARG poly (ADP-ribose) glycohydrolases
  • plants have several endogenous reaction mechanisms that can effectively prevent various harmful organisms and / or natural abiotic stress.
  • the object of the present invention was to provide further compounds which increase the tolerance to abiotic stress in plants, in particular to effect a strengthening of plant growth and / or contribute to increasing the plant yield.
  • R 13 , R 14 , R 15 , R 16 , R 17 , R 18 , R 19 , R 20 , R 23 , R 24 , R 25 , R 26 , R 28 , R 29 , R 30 , R 31 , R 32 , R 34 , R 35 and R 36 and A 1 to A 9 are each as defined below and wherein the arrow indicates a bond to the respective grouping CR 6 in the general formula (I) stands,
  • R 2 , R 3 and R 4 independently of one another represent hydrogen, alkyl, aryl, heteroaryl,
  • Trialkylsilylalkoxyalkyloxy stands, for nitro, amino, hydroxy, hydrothio, thiocyanato, isothiocyanato, halogen, alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl, arylalkynyl, trialkylsilylalkynyl, aryl, arylalkyl, arylalkoxy, heteroaryl, haloalkyl, halocycloalkyl, haloalkenyl, alkoxy, haloalkoxy, aryloxy, heteroaryloxy , Cycloalkyloxy, cycloalkylalkoxy, alkenyloxy, alkynylalkyloxy, hydroxyalkyl, alkoxyalkyl, aryloxyalkyl,
  • Haloalkylcarbonylamino alkoxycarbonylamino, alkylaminocarbonylamino, alkyl (alkyl) aminocarbonylamino, alkylsulfonylamino, cycloalkylsulfonylamino, arylsulfonylamino, hetarylsulfonylamino, sulfonylhaloalkylamino,
  • Aminoalkylsulfonyl aminohaloalkylsulfonyl, alkylaminosulfonyl,
  • Alkoxyalkoxycarbonyl alkenyloxyalkoxycarbonyl, alkylaminoalkoxycarbonyl, trisalkylsilyloxyalkoxycarbonyl, bis-alkylaminoalkoxycarbonyl,
  • Heterocyclylalkoxycarbonyl heterocyclyloxycarbonyl, alkenylalkoxycarbonyl, alkynylalkoxycarbonyl, arylalkynyloxycarbonyl, arylalkenyloxycarbonyl,
  • Aminocarbonyl alkylaminocarbonyl, bisalkylaminocarbonyl,
  • Heteroarylalkylaminocarbonyl cyanoalkylaminocarbonyl, Haloalkylaminocarbonyl, alkynylalkylaminocarbonyl,
  • Alkoxycarbonylheterocyclyl alkenyloxycarbonylheterocyclyl,
  • Arylalkylaminocarbonylheterocyclyl alkenylaminocarbonylheterocyclyl,
  • Aminosulfonyl alkoxyalkylaminocarbonyl, alkoxycarbonylheterocyclyl-N- carbonyl, alkoxycarbonylalkylheterocyclylidenaminocarbonyl,
  • Alkoxycarbonylalkyl (alkyl) aminocarbonyl
  • R 1 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
  • R 13 , R 14 , R 15 and R 16 are each independently hydrogen, halogen, nitro, amino, cyano, alkyl, aryl, heteroaryl, cycloalkyl, cycloalkenyl, alkenyl, alkynyl, alkenylalkyl, alkynylalkyl, hydroxy, alkoxy, alkoxyalkoxy, alkoxyalkyl,
  • Aminoalkylsulfonyl aminohaloalkylsulfonyl, alkylaminosulfonyl,
  • R 21 and R 22 are each independently hydrogen, halogen, alkyl, aryl, heteroaryl, heterocyclyl, cycloalkyl, alkenyl, alkoxy, alkoxyalkyl, aryloxyalkyl, haloalkoxy, haloalkyl, haloalkoxyalkyl, alkoxyhaloalkyl, haloalkoxyhaloalkyl, alkylthio, haloalkylthio, alkylthioalkyl, hydroxycarbonyl, alkoxycarbonyl .
  • R 3 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
  • R 7 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
  • R 33 is hydrogen, halogen, (DC 8) alkyl, aryl, heteroaryl, heterocyclyl, (Ca-C8) - cycloalkyl. (C 2 -C 8) alkenyl, (DC 8) alkoxy, (Ci-C 8) alkoxy (CrC 8) alkyl,
  • R 2 , R 3 and R 4 independently of one another represent hydrogen, halogen, (C 1 -C 7 ) -alkyl,
  • R 5 is hydroxy, (dC 7) alkoxy, aryloxy, (C 3 -C 7) cycloalkyloxy, (C 2 -C 7) alkenyloxy, (C 2 -C 7) alkenyl (CrC 7) - alkyioxy, (CrC 7) alkoxy (Ci-C7) alkyloxy, (C1-C7) - alkylcarbonyloxy, arylcarbonyloxy, Heteroarylcarbonyioxy, (C3-C7) - cycloalkylcarbonyloxy, (Ci-C7) alkoxycarbonyloxy, (C 2 -C 7) - Aikenyioxycarbonyloxy, Aryioxy- (Ci-C 7) -aikyloxy, aryl (Ci-C 7) -alkyioxy, (C1-C7) - alkoxy (Ci-C7) alkoxy (CrC 7) -acyloxy, (C
  • (C 1 -C 7 ) -alkylamino bis [(C 1 -C 7 ) -alkyl] -amino, (C 2 -C 7 ) -alkenylamino, (C 1 -C -cycloalkylamino, (C 1 -C 7 ) -alkylcarbonylamino, (C 3 -C7) - cycloalkylcarbonylamino, arylcarbonylamino, heteroarylcarbonylamino, formylamino, (C 1 -C 7 ) -haloalkylcarbonylamino, (C 1 -C 7 ) -alkoxycarbonylamino, (C 1 -C 7 ) -alkylaminocarbonylamino, (C 1 -C 7 ) -alkyl [(Ci-C 7 ) alkyl] aminocarbonylamino, (C 1 -C 7 ) -alkylsulfon
  • heteroaryloxycarbonyl heteroaryl- (C 1 -C 7) -alkoxycarbonyl, heterocyclyl- (C 1 -C 7) -alkoxycarbonyl, heterocyclyloxycarbonyL (C 2 -C 7) -alkenyl- (C 1 -C 7) -alkoxycarbonyl, (C 2 -C 7) -alkynyl- (C 1 -C 7) -alkoxycarbonyl , Aryl- (C 2 -C 7) -alkynyloxycarbonyl, aryl- (C 2 -C 7) -alkenyloxycarbonyl, aminocarbonyl, (C 1 -C 7) -alkylaminocarbonyl, bis [(C 1 -C 7) -alkyl] aminocarbonyl, (C 1 -C 7) -alkyl [(C-C7) - Alkyl] aminocarbonyl, (C 1 -C 7)
  • R 3 and R 4 with the atom to which they are attached, an exo-alkylidene group or a fully saturated, optionally substituted by O (oxygen), S
  • R 1 and R 11 optionally form further substituted 3 to 6-membered ring, R 1 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
  • R 1 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
  • R 3 and R 7 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
  • R 3 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
  • R 1 and R 3 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
  • R 7 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
  • R 3 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form
  • R 7 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 3 to 7-membered ring form
  • R 3, R 14, R 15 and R 16 are independently hydrogen, halogen, nitro, amino, cyano, (CrC 7) alkyl, aryl, heteroaryl, (C 3 -C 7) cycloalkyl, (C 4 -C 7) cycloalkenyl, (C2-C7) alkenyl, (C 2 -C 7) -alkynyl, (C2-C7) alkenyl (Ci-C7) alkyl, (C 2 -C 7) - Alkynyl- (C 1 -C 7 ) -alkyl, hydroxy, (C 1 -C 7 ) -alkoxy, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -alkoxy, (C 1 -C 7 ) -alkoxy- (dC 7) alkyl, hydroxy (dC 7) alkyl, (dC 7) -haloalkoxy, (C1-C7)
  • R 17 and R 18 are independently hydrogen, halogen, (dC 7) alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 7) cycloalkyl, (C 2 -C 7) alkenyl, (C 2 -C 7 ) alkynyl, (OO) alkoxy, (C 1 -C 7 ) alkoxy (C 1 -C 7 ) -alkyl, aryloxy (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -haloalkoxy, (C 1 -C 7 ) Haloalkyl, (C 1 -C 7 ) -haloalkoxy- (C 1 -C 7 ) -alkyl, (C 1 -C 4) -alkoxy- (C 1 -C 7 ) -haloalkyl, (C 1 -C 7 ) -haloalkyl, (C 1 -C 7 ) -
  • a 5 represents S (sulfur), O (oxygen) or the groupings NH, N-CH 3 , N-CH 2 CH 3 , N-CH (CH 3 ) 2 , N-CO 2 t-Bu, N-aryl, N-heteroaryl, N-heterocyclyl is
  • R 19, R 20, R 23 and R 24 are independently hydrogen, (Ci-C7) alkyl, halogen, (C 3 -C 7) cycloalkyl, aryl, heteroaryl, heterocyclyl, (C 2 -C 7) alkenyl, (C 2 -C 7) - alkenyl, (C, -C7) alkyl, aryl (dC 7) alkyl, (dC 7) alkoxy, (Ci-C7) alkoxy (Ci -C 7) - alkoxy, (Ci-C7) alkoxy (Ci-C7) alkyl, hydroxy, (dC 7) -haloalkyl, (C1-C7) - haloalkylthio stand,
  • R 19 and R 23 with the atoms to which they are attached form a completely saturated or partially saturated, optionally further substituted 5 to 7-membered ring,
  • a 6 , A 7 are identical or different and independently of one another represent O (oxygen), S (sulfur), NH, N-OCH 3, N-CH 3 or the group CR 21 R 22 , where however, in no case are two N, O or S atoms adjacent, and wherein R 21 and R 22 in the group CR 21 R 22 are each the same or different
  • R 22 have meanings as defined below and R 22 and are independently hydrogen, halogen, (Ci-C 7) alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 7) cycloalkyl, (C 2 -C 7) - Alkenyl, (C 1 -C 7 ) -alkoxy, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -alkyl, aryloxy- (C 1 -C 7 ) -alkyl, (C 1 -C 4 ) -haloalkoxy, (C 1 -C 4 ) -alkoxy C7) - haloalkyl, (C 1 -C 7 ) -haloalkoxy- (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -alkoxy- (C 1 -C 4 ) -haloalkyl, (C 1 -C 7 )
  • (C 1 -C 7) -alkylaminocarbonyl bis [(C 1 -C 7) -alkyl] aminocarbonyl, (C 1 -C 7) -alkyl [(C 1 -C 7) -alkyl] aminocarbonyl, (C 1 -C 7) -alkyl [(C 1 -C 7)] Alkoxy] aminocarbonyl, (C 2 -C 7) -alkenylaminocarbonyl, (C 3 -C 7) -cycloalkylaminocarbonyl,
  • R 30 , R 31 , R 32 , R 34 , R 35 and R 36 independently of one another represent hydrogen, (C 1 -C 7 ) -alkyl, halogen, (C 3 -C 7 ) -cycloalkyl, aryl, heteroaryl, heterocyclyl, ( C 2 -C 7 ) -alkenyl, (C 1 -C 7 ) -alkoxy, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -alkoxy, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -alkyl, (Ci-C7) haloalkyl, (Ci-C7) alkylthio, (CrC 7) are haloalkylthio,
  • a 9 is O (oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the group CHR 33 , and wherein R 33 in the group CHR 33 has the meaning as defined below and
  • R 33 is hydrogen, halogen, (C 1 -C 7 ) -alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 7 ) -cycloalkyl, (C 2 -C 7 ) -alkenyl, (C 1 -C 7 ) -alkoxy, (Ci -C 7) alkoxy (Ci-C7) alkyl, aryloxy (Ci-C7) alkyl, (Ci-C7) haloalkoxy, (Ci-C7) haloalkyl, (Ci-C 7) Alkylthio, (C 1 -C 7) -haloalkylthio, hydroxycarbonyl, (C 1 -C 7) -alkoxycarbonyl, (C 3 -C 7) -cycloalkoxycarbonyl, aryl- (C 1 -C 7) -alkoxycarbonyl, (C 2 -C 7) -alkenyl
  • R 1 is (C 1 -C 6 ) -alkyl, (C 3 -C 6 ) -cycloalkyl, (C 4 -C 6 ) -cycloalkenyl, (C 2 -C 6 ) -alkenyl, (C 2 -C 6 ) - Alkynyl, (C 2 -C 6 ) -alkenyl- (C 1 -C 6 ) -alkyl, (C 2 -C 6 ) -alkynyl- (C 1 -C 6 ) -alkyl,
  • R 2 , R 3 and R 4 independently of one another represent hydrogen, fluorine, chlorine, bromine, iodine,
  • R 5 is hydroxy, (C 1 -C 6 ) -alkoxy, aryloxy, (C 3 -C 6 ) -cycloalkyloxy, (C 2 -C 6 ) -alkenyloxy, (C 2 -C 6 ) -alkenyl- (C 1 -C 6 ) -alkyloxy, ( C 1 -C 6 -alkoxy- (C 1 -C 6 ) -alkyloxy, (C 1 -C 6 ) -alkylcarbonyloxy, arylcarbonyloxy, heteroarylcarbonyloxy, (C 3 -G 3) -cycloalkylcarbonyloxy, (C 1 -C 6 ) -alkoxycarbonyloxy, (C 2 -C 6 ) Alkenyloxycarbonyloxy, aryloxy- (C 1 -C 6 ) -alkyloxy, aryl- (C 1 -C 6 ) -alkyl
  • R 6 for nitro, amino, hydroxy, hydrothio, thiocyanato, isothiocyanato, fluorine, chlorine,
  • heteroaryloxycarbonyl heteroaryl- (C 1 -C 6) -alkoxycarbonyl, heterocyclyl- (C 1 -C 6) -alkoxycarbonyl, heterocyclyloxycarbonyl, (C 2 -C 6) -alkenyl- (C 1 -C 6) -alkoxycarbonyl, (C 2 -C 6) -alkynyl- (Ci -C6) alkoxycarbonyl, aryl- (C2-Ce) alkynyloxycarbonyl, aryl- (C2-C6) -alkenyloxycarbonyl, aminocarbonyl, (d-Ce) -alkylaminocarbonyl, bis [(Ci-C6) -alkyl] aminocarbonyl, (Ci -C6) alkyl [(d-C6) alkyl] aminocarbonyl, (Ci-C6) alkyl [(CrC6) alkoxy] aminocarbonyl, (C 2
  • C3-C6) cycloalkyl (Ci-C 6) alkoxycarbonyl (Ci-C 6) alkyl, (C 2 -C 6) - alkenyloxycarbonyl (CRC6) alkyl, aryl (Ci-C6) - alkoxycarbonyl- (C 1 -C 6) -alkyl, (C 1 -C 6) -alkylaminocarbonyl (C 1 -C 6) -alkyl, aminocarbonyl- (C 1 -C 6) -alkyl,
  • Aminoiminomethyl (C 1 -C 6) -alkoxyiminomethyl, (C 1 -C 6) -alkylaminoiminomethyl, bis [(C 1 -C 6) -alkyl] aminoiminomethyl, (C 3 -C 6) -cycloalkoxyiminomethyl, (C 3 -C 6) -cycloalkyl- (Ci -C6) -alkoximinomethyl, aryloximinomethyl, aryl- (Ci-CG) -alkoxyiminomethyl, aryl- (Ci-C6) -alkylaminoiminomethyl, (C2-C-6) -alkenyloxyiminomethyl, arylaminoiminomethyl, arylsulfonylaminoiminomethyl, heteroaryl- (Ci-C 6 ) -alkyl, heterocyclyl- (C 1 -C 6 ) -alkyl,
  • R 3 and R 4 with the atom to which they are attached, an exo-alkylidene group or a fully saturated, optionally substituted by O (oxygen), S
  • R 3 and R 7 with the atoms to which they are attached, a fully saturated or partially saturated, optionally by O (oxygen), S (sulfur) or form a group NH, NR 37 interrupted and optionally further substituted 5 to 7-membered ring,
  • R 3 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
  • R 1 and R 3 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
  • R 7 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
  • R 3 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
  • R 7 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
  • R 13, R 14, R 15 and R 16 independently of one another represent hydrogen, fluorine, chlorine, bromine, iodine, nitro, amino, cyano, (Ci-Ce) alkyl, optionally substituted phenyl, heteroaryl, (C 3 -C 6 ) cycloalkyl, (C 4 -C 6) -cycloalkenyl, (C 2 -C 6) alkenyl, (C 2 -C 6) - alkynyl, (C2-C6) alkenyl (Ci-C 6) - alkyl, (C 2 -C 6 ) -alkynyl- (C 1 -C 6 ) -alkyl, hydroxyl, (C 1 -C 6 ) -alkoxy, (C 1 -C 6 ) -alkoxy- (C 1 -C 6 ) -alkoxy, ( Ci-C 6) alkoxy (Ci-C6) alkyl, hydroxy (Ci-
  • a 1 , A 2 , A 3 and A 4 are the same or different and are independently N
  • R 17 and R 18 independently of one another represent hydrogen, halogen, (C 1 -C 6 ) -alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 6 ) -cycloalkyl, (C 2 -C 6 ) -alkenyl, (C 2 -) C 6 ) -alkynyl, (C 1 -C 6 ) -alkoxy, (C 1 -C 6 ) -alkoxy- (C 1 -C 6 ) -alkyl, aryloxy- (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -haloalkoxy, ( C 1 -C 6 ) -haloalkyl, (C 1 -C 6 ) -haloalkyl, (C 1 -C 6 ) -haloalkoxy- (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -
  • R 19 , R 20 , R 23 and R 24 independently of one another represent hydrogen, (C 1 -C 6 ) -alkyl, halogen, (C 3 -C 6 ) -cycloalkyl, aryl, heteroaryl, heterocyclyl, (C 2 -C 6 ) - alkenyl, (C 2 -C 6) - alkenyl, (CrC 6) alkyl, aryl (Ci-C 6) alkyl, (Ci-Ce) alkoxy, (Ci-C 6) alkoxy (Ci- C 6) - alkoxy, (Ci-C6) alkoxy (Ci-C 6) alkyl, hydroxy, (CrC 6) -haloalkyl, (dC 6) - haloalkylthio stand,
  • R 25 , R 26 , R 28 and R 29 independently of one another represent hydrogen, (C 1 -C 6 ) -alkyl, halogen, (C 3 -C 6 ) -cycloalkyl, aryl, heteroaryl, heterocyclyl, (C 2 -C 6 ) - alkenyl, aryl (Ci-Ce) - alkyl, (Ci-Ce) alkoxy, (Ci-C6) alkoxy (Ci-C 6) alkoxy, (Ci-C 6) alkoxy (Ci- C 6 ) -alkyl, (C 1 -C 6 ) -haloalkyl,
  • a 8 is O (oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the moiety CHR 27 , and wherein R 27 in the moiety CHR 27 has the meaning as defined below,
  • R 27 is hydrogen, halogen, (Ci-CeJ-alkyl, aryl, heteroaryl, heterocyclyl, (C3-Ce) - cycloalkyl, (C 2 -C 6) alkenyl, (Ci-C 6) alkoxy, (Ci- C 6 ) -alkoxy- (C 1 -C 6 ) -alkyl, aryloxy- (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -haloalkoxy, (C 1 -C 6 ) -haloalkyl.
  • (C 1 -C 6) -alkylaminocarbonyl bis [(C 1 -C 6) -alkyl] aminocarbonyl, (C 1 -C 6) -alkyl [(C 1 -C 6) -alkyl] aminocarbonyl, (C 1 -C 6) -alkyl [(C 1 -C 6) -alkoxy] aminocarbonyl, (C 2 -C 6) -alkenylaminocarbonyl, (C 3 -C 6) -cycloalkylaminocarbonyl,
  • R 30 , R 31 , R 32 , R 34 , R 35 and R 36 are each independently hydrogen.
  • a 9 is O (oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the group CHR 33 and wherein R 33 in the group CHR 33 has the meaning as defined below and
  • R 33 is hydrogen, halogen, (C 1 -C 6 ) -alkyl, aryl, heteroaryl, heterocyclyl, (C 1 -C 6 ) -cycloalkyl, (C 2 -C 6 ) -alkenyl, (C 1 -C 6 ) -alkoxy, ( C 6 ) -alkoxy- (C 1 -C 6 ) -alkyl, aryloxy- (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -haloalkoxy, (C 1 -C 6 ) -haloalkyl, (C 1 -C 4) - Alkylthio, (C 1 -C 6) -haloalkylthio, hydroxycarbonyl, (C 1 -C 6) -alkoxycarbonyl, (C 1 -C 6) -cycloalkoxycarbonyl, aryl- (C 1 -C 6)
  • R 37 is (Ci-C 6) alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 6) -cycloalkyl, (C 2 -C 6) alkenyl, (Ci-C 6) alkoxy, (Ci- C 6) alkoxy- (Ci-C 6) alkyl, aryloxy (Ci-Cr>) alkyl, (Ci-C6) - alkoxycarbonyl, (C3-C6) - cycloalkoxycarbonyl, aryl (Ci-C6) alkoxycarbonyl, (C 2 -C 6) alkenyloxycarbonyl, (C 2 -C 6) alkynyloxycarbonyl, (C 1 -C 6) alkylcarbonyl, (C 3 -C 18) cycloalkylcarbonyl, arylcarbonyl, heteroarylcarbonyl.
  • R 13 , R 14 , R 15 , R 16 , R 17 , R 18 , R 19 , R 20 , R 23 , R 24 , R 25 , R 26 , R 28 , R 29 , R 30 , R 31 , R 32 , R 34 , R 35 and R 36 and A 1 to A 9 each have the meaning as defined below and wherein the arrow for a bond to the respective group CR 6 in the aforementioned formulas (la) to (lo) .
  • R 5 is hydroxy, (C 1 -C 6 ) -alkoxy, aryloxy, (C 3 -C 8) -cycloalkyloxy, (C 2 -C 6 ) -alkenyloxy, (C 2 -C 6 ) -alkenyl- (C 1 -C 6 ) -alkyloxy, (C 1 -C 6 ) -alkoxy- (C 1 -C 6 ) -alkyloxy, (C 1 -C 6 ) -alkylcarbonyloxy, arylcarbonyloxy, heteroarylcarbonyloxy, (Ca-Ce) -cycloalkylcarbonyloxy, (d-CeJ-alkoxycarbonyloxy, (Cz-Ce Alkenyloxycarbonyloxy, aryloxy- (C 1 -C 6 ) -alkyloxy, aryl- (C 1 -C 6 ) -alkyloxy, (C 1 -
  • R 6 represents nitro, amino, hydroxy, Hydrothio, thiocyanato, isothiocyanato, fluorine, chlorine, bromine, iodine, (CrC 6) alkyl, (C 3 -C 6) -cycloalkyl, (C 2 -C 6) alkenyl, (C 4 -C 6) - cycloalkenyl, (C 2 -C 6) alkynyl, aryl (C2-C6) -alkynyl, tris [(Ci-C6) alkyl] silyl (C2-C 6) - alkynyl, aryl, aryl (Ci-C 6) alkyl, aryl (Ci-C 6) alkoxy, heteroaryl, (dC 6) - haloalkyl, (C 3 -C 6) halocycloalkyl, (C 2 - C 6) haloalkenyl, (Ci-C 6) alk
  • R 31 , R 32 , R 34 , R 35 and R 36 independently of one another represent hydrogen, (C 1 -C 5) -alkyl, fluorine, chlorine, bromine, iodine, (C 1 -C 6 -cycloalkyl, optionally substituted phenyl, heteroaryl, heterocyclyl, (C 2 -C 5) alkenyl, (Ci-C 5) alkoxy, (C1-C5) - haloalkyl, (CrC 5) alkylthio, (Ci-C 5) are haloalkylthio,
  • a 9 is O (oxygen), S (sulfur), NH, N-CH 3, N -OCH 3 or the group CHR and wherein R 33 in the group CHR 33 has the meaning as defined below and
  • R 33 is hydrogen, halogen, (C 1 -C 8 -alkyl, optionally substituted phenyl, heteroaryl, heterocyclyl, (C 3 -C 6 ) -cycloalkyl, (C 2 -C 5 ) -alkenyl, (C 1 -C 5 ) -alkoxy, (Ci -C r>) alkoxy (Ci-C 5) alkyl, (CrC 5) haloalkoxy, (Ci-C5) haloalkyl, (C1-C5) - alkylthio, (Ci-C5) haloalkylthio , Hydroxycarbonyl, (C 1 -C 5) -alkoxycarbonyl, (C 3 -C 6) -cycloalkoxycarbonyl, aryl- (C 1 -C 5) -alkoxycarbonyl, (C 2 -C 5) -alkenyloxycarbonyl, (C 2
  • Ethylaminosulfonyl n-propylaminosulfonyl, iso-propylaminosulfonyl, n-butylaminosulfonyl, tert-butylaminosulfonyl, iso-butylaminosulfonyl,
  • Aminoiminomethyl (Ci-C5) -alkoxyiminomethyl, (Ci-C5) -alkylaminoiminomethyl, bis [(Ci-C5) -alkyl] aminoiminomethyl, (C3-C6) -cycloalkoxyiminomethyl, (CS-CG) -cycloalkyl- (Ci-Cr ») -alkoximinomethyl, Aryloximinomethyl, aryl (Ci-Cr>) - alkoxyiminomethyl, aryl (Ci-C5) -alkylaminoiminomethyl, (C2-C5) - Alkenyloxyiminomethyl, Arylaminoiminomethyl, Arylsulfonylaminoiminomethyl, heteroaryl (CrCr>) alkyl, heterocyclic - (C 1 -C 5 ) -alkyl,
  • R 13 , R 14 , R 15 and R 16 independently of one another represent hydrogen, fluorine, chlorine, bromine, iodine, nitro, amino, cyano, methyl, ethyl, n-propyl, isopropyl, n-butyl, sec-butyl, iso-butyl, tert. Butyl, cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl,
  • R 17 and R 18 independently of one another represent hydrogen, fluorine, chlorine, bromine, iodine, methyl, ethyl, isopropyl, optionally substituted phenyl, heteroaryl,
  • R 19 , R 2Ü , R 23 and R 24 are each independently hydrogen, methyl, ethyl, iso-propyl, fluorine, chlorine, bromine, iodine, cyclopropyl, cyclobutyl, cyclopentyl,
  • Cyclohexyl optionally substituted phenyl, heteroaryl, heterocyclyl, trifluoromethyl, difluoromethyl,
  • R 19 and R 23 with the atoms to which they are attached form a completely saturated or partially saturated, optionally further substituted 5 to 7-membered ring,
  • a 6 , A 7 are identical or different and independently of one another represent O (oxygen), S (sulfur), NH, N-OCH 3, N-CH 3 or the group CR 2 R 22 , but in no case are two N , O or S atoms are adjacent, and wherein R 21 and R 22 in the group CR 21 R 22 are each the same or different
  • R 21 and R 22 independently of one another are hydrogen, fluorine, chlorine, bromine, iodine, methyl, ethyl, isopropyl, n-propyl, optionally substituted phenyl, heteroaryl, heterocyclyl, cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, methoxy, ethoxy, Trifluoromethyl, difluoromethyl, trifluoromethoxy, methylthio,
  • Aminocarbonyl methylaminocarbonyl, ethylaminocarbonyl, n-propylaminocarbonyl, iso-propylaminocarbonyl, dimethylaminocarbonyl, cyclopropylaminocarbonyl, cyclobutylaminocarbonyl,
  • R 25 , R 26 , R 28 and R 29 independently of one another represent hydrogen, methyl, ethyl, n-propyl, isopropyl, n-butyl, tert-butyl, cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, fluorine, chlorine, bromine , iodine, optionally substituted phenyl, heteroaryl, heterocyclyl, methoxy, ethoxy, trifluoromethyl, difluoromethyl,
  • R 30 , R 31 , R 32 , R 34 , R 35 and R 36 independently of one another are hydrogen, methyl, ethyl, n-propyl, isopropyl, fluorine, chlorine, bromine, iodine, cyclopropyl, optionally substituted phenyl, heteroaryl, Heterocyclyl, methoxy, ethoxy, n-propyloxy, iso-propyloxy, trifluoromethyl, difluoromethyl, methylthio, trifluoromethylthio,
  • a 9 is O (oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the group CHR and wherein R 33 in the group CHR 33 has the meaning as defined below, and
  • Residue definitions apply both to the end products of the general formula (I) and correspondingly to the starting material or preparation required in each case for the preparation
  • R 1 is (Ci-C7) alkyl, (C 3 -C 7) cycloalkyl, (C 4 -C 7) cycloalkenyl, (C2-C7) alkenyl, (C 2 -C 7) alkynyl , (C 2 -C 7) alkenyl (Ci-C7) alkyl, (C 2 -C 7) alkynyl (Ci-C7) alkyl,
  • I 3 and R 4 independently of one another represent hydrogen, halogen, (C 1 -C 7 ) -alkyl,
  • R 7 , R 8 , R 9 , R 10 , R 11 and R 12 are independently hydrogen.
  • R 3 and R 4 with the atom to which they are attached, an exo-alkylidene group or a fully saturated, optionally substituted by O (oxygen), S
  • R 1 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
  • R 1 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form
  • R 3 and R 7 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 5 to 7-membered ring form
  • R 3 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
  • R 1 and R 3 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
  • R 7 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
  • R 3 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
  • R 7 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
  • R 13 , R 14 , R 5 and R 16 independently represent hydrogen, halogen, nitro, amino, cyano.
  • Alkylaminocarbonyl bis [(Ci-C 7) alkyl] aminocarbonyl, (Ci-C 7) alkyl [(Ci-C 7) - Alkyljaminocarbonyl, (CrC 7) alkyl [(Ci-C7) alkoxy] aminocarbonyl , (C 2 -C 7 ) alkenylaminocarbonyl, (C 3 -C 7 ) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 7 ) -alkylaminocarbonyl,
  • R 20, R 23 and R 24 are independently hydrogen, (Ci-C7) alkyl, halogen, (C 3 -C 7) cycloalkyl, aryl, heteroaryl, heterocyclyl, (C2-C7) alkenyl, ( C2-C7) - alkenyl (-C 7) alkyl, aryl (-C 7) alkyl, (dC 7) alkoxy, (Ci-C7) alkoxy (CrC 7) - alkoxy, (Ci-C 7 ) alkoxy- (C 1 -C 7 ) -alkyl, hydroxy, (C 1 -C 7 ) -haloalkyl, (C 1 -C 7 ) -haloalkylthio, and R 23 having the atoms to which they are attached, a fully saturated or partially saturated, optionally form further substituted 5 to 7-membered ring,
  • a 6 , A 7 are identical or different and independently of one another represent O (oxygen), S (sulfur), NH, N-OCH 3, N-CH 3 or the group CR 21 R 22 , but in no case are two N , O or S atoms are adjacent, and wherein R 21 and R 22 in the group CR 21 R 22 are each the same or different
  • R 27 represents hydrogen, halogen, (C 1 -C 7 ) -alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 7 ) -cycloalkyl, (C 2 -C 7 ) -alkenyl, (C 1 -C 7 ) -alkoxy, (Ci-C 7 ) -alkoxy- (C 1 -C 7 ) -alkyl, aryloxy- (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -haloalkoxy, (C 1 -C 7 ) -haloalkyl, (C 1 -C 7 ) -alkoxy (C 1 -C 7 ) -haloalkyl, (C 1 -C 7 ) -haloalkyl, (C 1 -C 7 ) -haloalkoxy- (C 1 -C 7 ) -haloalkyl, (C 1
  • R 30 , R 31 , R 32 , R 34 , R 35 and R 36 independently of one another are hydrogen, (C 1 -C 7 ) -alkyl, halogen, (C 3 -C 7 ) -cycloalkyl, aryl, heteroaryl, heterocyclyl, (C 2 -C 4 ) -cycloalkyl, C7) alkenyl, (Ci-C7) alkoxy, (Ci-C7) alkoxy (Ci-C7) alkoxy, (Ci-C7) alkoxy (Ci-C7) alkyl, (dC 7) -haloalkyl , (C 1 -C 7 ) -alkylthio, (C 1 -C 4 ) -haloalkylthio,
  • a 9 is O (oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the group CHR 33 and wherein R 33 in the group CHR 33 has the meaning as defined below and
  • R 33 is hydrogen, halogen, (dC 7) alkyl, aryl, heteroaryl, heterocyclyl, (C3-C7) - cycloalkyl, (C 2 -C 7) alkenyl, (Ci-C7) alkoxy, (C -C 7) alkoxy (Ci-C7) alkyl, aryloxy (Ci-C7) alkyl, (Ci-C7) haloalkoxy, (Ci-C7) haloalkyl, (Ci-C 7 ) -Alkylthio, (C 1 -C 7 ) -haloalkylthio, hydroxycarbonyl, (C 1 -C 4 ) -alkoxycarbonyl, (C 3 -C 7 ) -cycloalkoxycarbonyl, aryl- (C 1 -C 7 ) -alkoxycarbonyl, (C 2 -C 7 ) -alkenyloxycarbonyl, (C 2
  • R 37 is (Ci-C /) -alkyl.
  • R 8 , R 9 , R 10 , R 11 and R 12 are not hydrogen and
  • R 3 and R 4 with the atom to which they are attached, an exo-alkylidene group or a fully saturated, optionally substituted by O (oxygen), S
  • R 1 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
  • R 1 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
  • R 3 and R 7 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
  • R 3 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
  • R 1 and R 3 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 5 to 7-membered ring form
  • R 7 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 5 to 7-membered ring form
  • R 3 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
  • R 7 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
  • R 13 , R 14 , R 15 and R 16 independently of one another represent hydrogen, fluorine, chlorine, bromine, iodine, nitro, amino, cyano, (C 1 -C 6 ) -alkyl, optionally substituted phenyl, heteroaryl, (C 3 -C 6 ) cycloalkyl, (C 4 -C 6) -cycloalkenyl, (C 2 -C 6) alkenyl, (C 2 -C 6) - alkynyl, (C2-C6) alkenyl (Ci-C 6) - alkyl, (C 2 -C 6 ) -alkynyl (C 1 -C 6 ) -alkyl, hydroxy, (C 1 -C 6 ) -alkoxy, (C 1 -C 6 ) -alkoxy- (C 1 -C 6 ) -alkoxy, C 6 ) -alkoxy- (C 1 -C 6 )
  • a 1 , A 2 , A 3 and A 4 are the same or different and are independently N
  • R 17 and R 18 independently of one another represent hydrogen, fluorine, chlorine, bromine, iodine, (C 1 -C 6 ) -alkyl, optionally substituted phenyl, heteroaryl, heterocyclyl, (C 1 -C 6 ) -cycloalkyl, (C 2 -C 6 ) - Alkenyl, (C 2 -C 6 ) -alkynyl, (C 1 -C 6 ) -alkoxy, (C 1 -C 6 ) -alkoxy- (C 1 -C 6 ) -alkyl, aryloxy- (C 1 -C 6 ) -alkyl, C 6 ) -haloalkoxy, (C 1 -C 6 ) -haloalkyl,
  • a 6 , A 7 are the same or different and are each independently O (oxygen), S (sulfur), NH, N-OCH 3 , N-CH 3 or the group CR 21 R 22 , but in no case two N -, O or S atoms are adjacent, and wherein R 21 and R 22 in the group CR 21 R 22 are identical or different
  • R 21 and R 22 independently of one another represent hydrogen, fluorine, chlorine, bromine, iodine, (d-Co) -alkyl, optionally substituted phenyl, heteroaryl, heterocyclyl, (Ca-Ce) -cycloalkyl, (C 2 -C 6) -alkenyl, (Ci-Cr,) - alkoxy, (Ci-C6) -alkoxy- (Ci-Cc,) - alkyl,
  • a 8 is O (oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the moiety CHR 27 , and wherein R 27 in the moiety CHR 27 has the meaning as defined below,
  • R 30 , R 31 , R 32 , R 34 , R 35 and R 36 independently of one another represent hydrogen, (C 1 -C 6 ) -alkyl, halogen, (C 3 -C 6 ) -cycloalkyl, aryl, heteroaryl, heterocyclyl, (C 2 -C 6) Alkenyl, (C 1 -C 6 ) -alkoxy, (C 1 -C 6 ) -haloalkyl, (C 1 -C 6 ) -alkylthio, (C 1 -C 6 ) -haloalkylthio,
  • a 9 is O (oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the group CHR 33 , and wherein R 33 in the group CHR 33 has the meaning as defined below and
  • R 33 represents hydrogen, fluorine, chlorine, bromine, iodine, (C 1 -C 6) -alkyl, if appropriate
  • R 5 is hydroxy, (d-CeJ) alkoxy, aryloxy, (C 1 -C 12 -cycloalkyloxy, (C 2 -C 6) -alkenyloxy, (C 2 -C 6 ) -alkenyl- (C 1 -C 6 ) -alkyloxy, ( C 1 -C 6 -alkoxy- (C 1 -C 6 ) -alkyloxy, (C 1 -C 6 ) -alkylcarbonyloxy, arylcarbonyloxy, heteroarylcarbonyloxy, (C 1 -C 6 ) -cycloalkylcarbonyloxy, (C 1 -C 6 -alkoxycarbonyloxy, (C 2 -C 6 ) - Alkenyloxycarbonyloxy, aryloxy- (C 1 -C 6 ) -alkyloxy, aryl- (C 1 -C 6 ) -alkyloxy, (d-C
  • R 6 is (C 1 -C 6 ) -alkylsulfonylaminocarbonyl, (Ca-Ce) -
  • R 21 and R 22 independently of one another represent hydrogen, fluorine, chlorine, bromine, iodine, (C 1 -C 5 ) -alkyl, optionally substituted phenyl, heteroaryl, heterocyclyl, (Ca-Ce) -cycloalkyl, (C 2 -C 5 ) - Alkenyl, (C 1 -C 5 ) -alkoxy, (C 1 -C 5 ) -alkoxy- (C 1 -C 5 ) -alkyl, (C 1 -C 5 ) -haloalkoxy.
  • R 25 , R 26 , R 28 and R 29 independently of one another represent hydrogen, (C 1 -C 5) -alkyl, fluorine, chlorine, bromine, iodine, (C 1 -C 6 -cycloalkyl, aryl, heteroaryl, heterocyclyl, (C 2 -C 5) - alkenyl, aryl- (-C 5) alkyl, (CrC 5) alkoxy, (Ci-C 5) -haloalkyl stand,
  • R 13 , R 14 , R 15 , R 16 , R 17 , R 18 , R 19 , R 20 , R 23 , R 24 , R 25 , R 26 , R 28 , R 29 , R 30 , R 31 , R 32 , R 34 , R 35 and R 36 and A 1 to A 9 each have the meaning as defined below and wherein the arrow for a bond to the respective group CR 6 in the aforementioned formulas (la) to (lo) , for hydroxy, methoxy, ethoxy, n-propyloxy, methylcarbonyloxy,
  • Arylaminoiminomethyl, arylsulfonylaminoiminomethyl, hydroxyaminocarbonyl, (C 1 -C 5) -alkoxyaminocarbonyl, aryl- (C 1 -C 6) -alkoxyaminocarbonyl, R 13 , R 14 , R 15 and R 16 are each independently hydrogen, fluoro, chloro, bromo, iodo, nitro , Amino, cyano, methyl, ethyl, n-propyl, iso-propyl, n-butyl, sec-butyl, iso-butyl, tert. Butyl, cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl,
  • Heteroarylcarbonylamino trifluoromethylcarbonylamino, methoxycarbonyiamino, ethoxycarbonylamino, methylsulfonylamino, ethylsulfonylamino, n-propylsulfonylamino, cyclopropylsulfonylamino, cyclobutylsulfonylamino, cyclopentylsulfonylamino, cyclohexylsulfonylamino, arylsulfonylamino,
  • a 1 , A 2 , A 3 and A 4 are the same or different and are independently N
  • R 17 and R 18 independently of one another represent hydrogen, fluorine, chlorine, bromine, iodine, methyl, ethyl, isopropyl, optionally substituted phenyl, heteroaryl,
  • R 19 , R 20 , R 23 and R 24 are each independently hydrogen, methyl, ethyl, iso-propyl, fluorine, chlorine, bromine, iodine, cyclopropyl, cyclobutyl, cyclopentyl,
  • R 21 and R 22 independently of one another are hydrogen, fluorine, chlorine, bromine, iodine, methyl, ethyl, isopropyl, n-propyl, optionally substituted phenyl, heteroaryl, heterocyclyl, cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, methoxy, ethoxy, Trifluoromethyl, difluoromethyl, trifluoromethoxy, methylthio,
  • Aminocarbonyl methylaminocarbonyl, ethylaminocarbonyl, n-propylaminocarbonyl, iso-propylaminocarbonyl, dimethylaminocarbonyl, cyclopropylaminocarbonyl, cyclobutylaminocarbonyl,
  • R 25 , R 26 , R 28 and R 29 independently of one another represent hydrogen, methyl, ethyl, n-propyl, isopropyl, n-butyl, tert-butyl, cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, fluorine, chlorine, bromine , iodine, optionally substituted phenyl, heteroaryl, heterocyclyl, methoxy, ethoxy, trifluoromethyl, difluoromethyl,
  • a 8 is O (oxygen), S (sulfur), NH, N-CH 3, N -OCH 3 or the moiety CHR 27 and wherein R 27 in the moiety CHR 27 has the meaning as defined below,
  • R 27 is hydrogen, fluorine, chlorine, bromine, iodine, methyl, ethyl, isopropyl, n-propyl,
  • R 30 , R 31 , R 32 , R 34 , R 35 and R 36 independently of one another are hydrogen, methyl, ethyl, n-propyl, isopropyl, fluorine, chlorine, bromine, iodine, cyclopropyl, optionally substituted phenyl, heteroaryl, Heterocyclyl, methoxy, ethoxy, n-propyloxy, iso-propyloxy, trifluoromethyl, difluoromethyl, methylthio, trifluoromethylthio.
  • a 9 is O (oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the group CHR and wherein R 33 in the group CHR 33 has the meaning as defined below, and
  • R 33 is hydrogen, fluorine, chlorine, bromine, iodine, methyl, ethyl, isopropyl, n-propyl,
  • Alkylamino, alkylcarbonylamino, dialkylamino or alkoxy groups
  • 3-membered and 4-membered heterocycles are, for example, 1- or 2-aziridinyl, oxiranyl, thiiranyl, 1- or 2- or 3-azetidinyl, 2- or 3-oxetanyl, 2- or 3-thietanyl, 1,3 -Dioxetan-2-yl.
  • Heterocyclyl are a partially or fully hydrogenated heterocyclic radical having two heteroatoms from the group N, O and S, such as 1- or 2- or 3- or 4-pyrazolidinyl; 4,5-dihydro-3H-pyrazole-3- or 4- or 5-yl; 4,5-dihydro-1H-pyrazole-1 or 3 or 4 or 5-yl; 2,3-dihydro-1H-pyrazole-1 - or 2- or 3- or 4- or 5-yl; 1- or 2- or 3- or 4-imidazolidinyl; 2,3-dihydro-1H-imidazole-1 - or 2- or 3- or 4-yl; 2,5-dihydro-1H-imidazole-1 - or 2- or 4- or 5-yl; 4,5-dihydro-1H-imidazole-1 - or 2- or 4- or 5-yl; Hexahydropyridazine-1 - or 2- or 3- or 4-yl; 1, 2,3,4-tetrahydropyridazine-1
  • 6- or 7-yl 1,4-oxazepine-2- or 3- or 5- or 6- or 7-yl; isothiazolidine-2- or 3- or 4- or 5-yl; 2,3-dihydroisothiazole-2- or 3- or 4- or 5-yl; 2.5-
  • quinazoline cinnoline; 1,5-naphthyridine; 1, 6-naphthyridine; 1,7-naphthyridine; 1 .8- naphthyridine; 2,6-naphthyridine; 2,7-naphthyridine; phthalazine; Pyridopyrazine;
  • a suitable base e.g., 2,6-lutidine
  • a suitable polar aprotic solvent e.g., dichloromethane
  • this reaction is described in Scheme 3 using triethylsilyl trifluoromethanesulfonate.
  • a suitable gold catalyst for example gold (III) bromide, gold (III) chloride
  • the substituted (E) -configured 1-arylvinyl-, 1-heteroarylvinyl-, 1-cycloalkenylvinylbicycloalkanols (I.5) can be prepared by reduction of the Aicyruppe of the corresponding substituted 1- (arylethynyl) -, 1 - (heteroarylethynyl) -, 1 - (Heterocyclylethynyl) - and 1 - (cycloalkenylethynyl) bicycloalkanols (1.1)
  • Transition metal catalyst such as Lindlar's catalyst with hydrogen in a suitable polar-apro tic solvent (such as n-butanol) perform (see Tetrahedron 1987, 43, 4107, Tetrahedron 1983, 39, 2315, J. Org. 1983, 48, 4436 and J. Am. Chem. Soc., 1984, 106, 2735) (Scheme 5).
  • R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , 7, R 8 , R 9 , R 10 , R 11 , R 12 and Q in Scheme 5 have the meanings defined above.
  • Fenchone (1500 mg, 9.85 mmol) was dissolved in a round bottom flask under argon in abs.
  • Tetra hydrofu ran (5 ml) and added dropwise to a solution of a lithium acetylide-ethylenediamine complex (1474 mg, 12.81 mmol, 80% content) in abs. Tetrahydrofuran (10 ml) was added. The reaction solution was stirred for 2 h after the addition at room temperature, then treated with water and concentrated under reduced pressure. The remaining residue was mixed with water and dichloromethane and the aqueous phase extracted several times with dichloromethane. The combined organic phases were dried over magnesium sulfate, filtered and concentrated under reduced pressure.
  • Tetra hydrofu ran (5 ml) and added dropwise to a solution of a lithium acetylide-ethylenediamine complex (1474 mg, 12.81 mmol, 80% content) in abs. Tetrahydrofuran (10 ml) was added. The reaction solution was stirred for 2 h after the addition at room temperature, then treated with water and concentrated under reduced pressure. The remaining residue was mixed with water and dichloromethane and the aqueous phase extracted several times with dichloromethane. The combined organic phases were dried over magnesium sulfate, filtered and concentrated under reduced pressure.
  • reaction mixture was stirred for 1 h at 0 ° C and then washed with sat.
  • Tetra hydrofu ran (5 ml) and added dropwise to a solution of a Lithiumacetylid-ethylenediamine complex (1962 mg, 9.41 mmol, 90% content) in abs. Tetrahydrofuran (3 ml).
  • the reaction solution was stirred for 4 h after the addition at room temperature, then treated with water and concentrated under reduced pressure. The remaining residue was mixed with water and dichloromethane and the aqueous phase extracted several times with dichloromethane. The combined organic phases were dried over magnesium sulfate, filtered and concentrated under reduced pressure.

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Abstract

The invention relates to the use of substituted 1 -(aryl ethynyl)-, 1 - (heteroaryl ethynyl)-, 1 -(heterocyclyl ethynyl)- and 1 -(cyloalkenyl ethynyl)- bicycloalkanols or salts thereof (I). The groups in general formula (I) correspond to the definitions cited in the description, for increasing the stress tolerance in plants with respect to abiotic stress and/or for increasing plant yield.

Description

Verwendung substituierter 1 -(Arylethinyl)-, 1 -(Heteroarylethinyl)-, 1 - (Heterocyciyiethinyl)- und 1-(Cyloalkenylethinyl)-bicycloalkanole als Wirkstoffe gegen abiotischen Pflanzenstress  Use of substituted 1 - (arylethynyl) -, 1 - (heteroarylethynyl) -, 1 - (heterocyclicylthioyl) - and 1- (cycloalkenylethynyl) bicycloalkanols as active substances against abiotic plant stress
Beschreibung Die Erfindung betrifft die Verwendung substituierter 1 -(Arylethinyl)-, 1 -Description The invention relates to the use of substituted 1 - (arylethynyl) -, 1 -
(Heteroarylethinyl)-, 1 -(Heterocyciyiethinyl)- und 1 -(Cyloalkenylethinyl)-bicycloalkanole zur Steigerung der Stresstoleranz in Pflanzen gegenüber abiotischem Stress und/oder zur Erhöhung des Pflanzenertrags. Es ist bekannt, dass bestimmte 5-(1 ,2-Epoxy-2,6,6-trimethylcyclohexyl)-3-methylpenta- 2,4-diensäuren und ihre Derivate Eigenschaften besitzen, die den Pflanzenwuchs beeinflussen (vgl. NL681 1769, DE1953152). Die Verwendung von 3-Methyl-5-(1 - hydroxy-2,2.6-trimethylcyclohexyl)-2-cis-4-trans-pentadiensäuremethylester gegen Frostschäden bei japanischen Dattelpflaumbäumen, Trauben und Maulbeeren wird ebenfalls in DE1953152 beschrieben. Die Verwendung von substituierten 5-Cyclohex- 2-en-1 -yl-penta-2,4-dienyl- und 5-Cyclohex-2-en-1 -yl-pent-2-en-4-inyl-olen, -thioethern und aminen als Inhibitoren der Epoxycarotenoiddioxygenase und als (Heteroarylethynyl) -, 1 - (Heterocyciyiethinyl) - and 1 - (Cyloalkenylethinyl) bicycloalkanols for increasing the stress tolerance in plants to abiotic stress and / or to increase the plant yield. It is known that certain 5- (1,2-epoxy-2,6,6-trimethylcyclohexyl) -3-methylpenta- 2,4-dienoic acids and their derivatives have properties which influence plant growth (see NL681 1769, DE1953152 ). The use of 3-methyl-5- (1-hydroxy-2,2,6-trimethylcyclohexyl) -2-cis-4-trans-pentadienoic acid methyl ester against frost damage in Japanese persimmon trees, grapes and mulberries is also described in DE1953152. The use of substituted 5-cyclohex-2-en-1 -yl-penta-2,4-dienyl and 5-cyclohex-2-en-1-yl-pent-2-en-4-ynyl-ols, - Thioethers and amines as inhibitors of Epoxycarotenoiddioxygenase and as
Keimungsinhibitoren wird in US2010/0160166 beschrieben. Es ist ebenfalls bekannt, daß (2Z,4E)-5-[(1 S,6S)-1-Hydroxy-2,2.6-trimethylcyclohexyl]penta-2,4-diensäure und (2Z,4E)-5-[(1 R,6R)-1 -Hydroxy-2.2,6-trimethylcyclohexyl]penta-2,4-diensäure mit Cytochrom P707A interagieren (vgl. Current Med. Chem. 2010, 17, 3230). Germination inhibitors are described in US2010 / 0160166. It is also known that (2Z, 4E) -5 - [(1S, 6S) -1-hydroxy-2,2,6-trimethylcyclohexyl] penta-2,4-dienoic acid and (2Z, 4E) -5 - [( 1 R, 6R) -1-hydroxy-2,2,6-trimethylcyclohexyl] penta-2,4-dienoic acid interact with cytochrome P707A (see Current Med. Chem., 2010, 17, 3230).
Abscisinsäureanaloga, in denen die Rotation einer der beiden Doppelbindungen durch ein aromatisches System eingeschränkt ist, werden in Agric. & Biol. Chem. Jap. Soc. Bioscience, Biotechnol. Agrochem. 1986, 50, 1097 beschrieben. Abscisic acid analogs, in which the rotation of one of the two double bonds by an aromatic system is restricted, are described in Agric. & Biol. Chem. Jap. Soc. Bioscience, Biotechnol. Agrochem. 1986, 50, 1097.
Es ist ebenfalls bekannt, daß substituierte 1 -(Phenylethinyl)-cyclohexanole mit bestimmten Substituentengruppen in der meta-Position des Phenylrestes als It is also known that substituted 1 - (phenylethynyl) cyclohexanols with certain substituent groups in the meta position of the phenyl radical as
Wirkstoffe in der Augenheilkunde verwendet werden können (vgl. WO2009005794, WO2009058216). Weiterhin ist die Herstellung von bestimmten substituierten 1 - (Phenylethinyl)-bicycloalkanolen beschrieben, z. B. 5,5.6-Trimethyl-2- (phenylethinyl)bicyclo[2.2.1 ]heptan-2-ol und 5,5,6-Trimethyl-2- (phenylethinyl)bicyclo[2.2.1 ]hept-2-yiacetat (vgl. Zh. Org. Khim. 2007, 43, 679; Zh. Org. Khim. 2002, 38, 182), 1 .7,7-Trimethyl-2-(phenylethinyl)-bicyclo[2.2.1 ]heptan-2-ol (vgl. Zh. Org. Khim. 2002, 38, 182; Zh. Org. Khim. 2005, 41 , 853; Zh. Obshchei Khim. 2004, 74, 965) und 1 ,3,3-Trimethyl-2-(phenylethinyl)-bicyclo[2.2.1 ]heptan-2-ol (vgl. Compt. Rend. Acad. Sei 1968, 267, 91 1 ; Zh. Org. Khim. 2002, 38, 1316). Active ingredients in ophthalmology can be used (see WO2009005794, WO2009058216). Furthermore, the preparation of certain substituted 1- (phenylethynyl) bicycloalkanols is described, for. B. 5,5,6-trimethyl-2 (phenylethynyl) bicyclo [2.2.1] heptan-2-ol and 5,5,6-trimethyl-2- (phenylethynyl) bicyclo [2.2.1] hept-2-ylacetate (see Zh.Org.Khim. 43, 679; Zh. Org. Khim., 2002, 38, 182), 1, 7,7-trimethyl-2- (phenylethynyl) bicyclo [2.2.1] heptan-2-ol (see Zh.Org.Khim 2002, 38, 182; Zh. Org. Khim. 2005, 41, 853; Zh. Obshchei Khim. 2004, 74, 965) and 1,3,3-trimethyl-2- (phenylethynyl) bicyclo [2.2.1 ] heptan-2-ol (see Compt. Rend Acad., 1968, 267, 91 1, Zh. Org. Khim., 2002, 38, 1316).
Von den erfindungsgemäßen substituierten l-(Arylethinyl)-, 1 -(Heteroarylethinyl)-, 1 - (Heterocyclylethinyl)- und 1-(Cyloalkenylethinyl)-bicycloalkanolen ist dagegen die Verwendung zur Steigerung der Stresstoleranz in Pflanzen gegenüber abiotischem Stress, zur Stärkung des Pflanzenwachstums und/oder zur Erhöhung des Of the substituted 1- (arylethynyl) -, 1- (heteroarylethynyl) -, 1- (heterocyclylethynyl) - and 1- (cycloalkenylethynyl) -bicycloalkanols according to the invention, on the other hand, the use for increasing the stress tolerance in plants to abiotic stress is to strengthen plant growth and / or to increase the
Pflanzenertrags nicht beschrieben. Plant yield not described.
Es ist bekannt, dass Pflanzen auf natürliche Stressbedingungen, wie beispielsweise Kälte, Hitze, Trockenstress (Stress verursacht durch Trockenheit und/oder It is known that plants are susceptible to natural stress conditions such as cold, heat, drought stress (stress caused by dryness and / or
Wassermangel), Verwundung, Pathogenbefall (Viren, Bakterien, Pilze, Insekten) etc. aber auch auf Herbizide mit spezifischen oder unspezifischen Abwehrmechanismen reagieren können [Pflanzenbiochemie, S. 393-462 , Spektrum Akademischer Verlag, Heidelberg, Berlin, Oxford, Hans W. Heidt, 1996.; Biochemistry and Molecular Biology of Piants, S. 1 102-1203, American Society of Plant Physiologists, Rockville, Maryland, eds. Buchanan, Gruissem, Jones, 2000].  Lack of water), wounding, pathogen infestation (viruses, bacteria, fungi, insects) etc. but also can react to herbicides with specific or nonspecific defense mechanisms [Plant Biochemistry, pp. 393-462, Spektrum Akademischer Verlag, Heidelberg, Berlin, Oxford, Hans W. Heidt, 1996; Biochemistry and Molecular Biology of Piants, p. 1 102-1203, American Society of Plant Physiologists, Rockville, Maryland, eds. Buchanan, Gruissem, Jones, 2000].
In Pflanzen sind zahlreiche Proteine und die sie codierenden Gene bekannt, die an Abwehrreaktionen gegen abioti sehen Stress (z.B. Kälte, Hitze, Trockstress, Salz, Überflutung) beteiligt sind. Diese gehören teilweise zu Signaltransduktionsketten (z.B. Transkriptionsfaktoren, Kinasen, Phosphatasen) oder bewirken eine physiologische Antwort der Pflanzenzelle (z.B. lonentransport, Entgiftung reaktiver Sauerstoff- Spezies). Zu den Signalkettengenen der abioti sehen Stressreaktion gehören u.a. Transkriptionsfaktoren der Klassen DREB und CBF (Jaglo-Ottosen et al., 1998, Science 280: 104-106). An der Reaktion auf Salzstress sind Phosphatasen vom Typ AT PK und MP2C beteiligt. Ferner wird bei Salzstress häufig die Biosynthese von Osmolyten wie Prolin oder Sucrose aktiviert. Beteiligt sind hier z.B. die Sucrose- Synthase und Prolin-Transporter (Hasegawa et al., 2000, Annu Rev Plant Physiol Plant Mol Biol 51 : 463-499). Die Stressabwehr der Pflanzen gegen Kälte und Trockenheit benutzt z.T. die gleichen molekularen Mechanismen. Bekannt ist die Akkumulation von sogenannten Late Embryogenesis Abundant Proteins (LEA- Proteine), zu denen als wichtige Klasse die Dehydrine gehören (Ingram and Bartels, 1996, Annu Rev Plant Physiol Plant Mol Biol 47: 277-403, Close, 1997, Physiol Plant 100: 291 -296). Es handelt sich dabei um Chaperone, die Vesikel, Proteine und Membranstrukturen in gestressten Pflanzen stabilisieren (Bray, 1993, Plant Physiol 103: 1035-1040). Außerdem erfolgt häufig eine Induktion von Aldehyd- Deydrogenasen, welche die bei oxidativem Stress entstehenden reaktiven Sauerstoff- Spezies (ROS) entgiften (Kirch et al., 2005, Plant Mol Biol 57: 315-332). In plants numerous proteins and their coding genes are known, which are involved in defense reactions against abiotic stress (eg cold, heat, dry stress, salt, flooding). These belong in part to signal transduction chains (eg transcription factors, kinases, phosphatases) or cause a physiological response of the plant cell (eg ion transport, detoxification of reactive oxygen species). Transcriptional factors of the class DREB and CBF belong to the signal chain genes of the abioti stress reaction (Jaglo-Ottosen et al., 1998, Science 280: 104-106). The salt stress response involves AT PK and MP2C phosphatases. Furthermore, in salt stress the biosynthesis of osmolytes such as proline or sucrose is often activated. For example, sucrose synthase and proline transporters are involved here (Hasegawa et al., 2000, Annu Rev Plant Physiol Plant Mol Biol 51: 463-499). The stress control of plants against cold and Dryness partly uses the same molecular mechanisms. The accumulation of so-called Late Embryogenesis Abundant Proteins (LEA proteins), which include dehydrins as an important class, is known (Ingram and Bartels, 1996, Annu Rev Plant Physiol Plant Mol Biol 47: 277-403, Close, 1997, Physiol Plant 100: 291-296). These are chaperones that stabilize vesicles, proteins and membrane structures in stressed plants (Bray, 1993, Plant Physiol 103: 1035-1040). Moreover, induction of aldehyde dehydrogenases, which detoxify the reactive oxygen species (ROS) produced by oxidative stress, is often used (Kirch et al., 2005, Plant Mol Biol 57: 315-332).
Heat Shock Faktoren (HSF) und Heat Shock Proteine (HSP) werden bei Hitzestress aktiviert und spielen hier als Chaperone eine ähnliche Rolle wie die Dehydrine bei Kälte- und Trockenstress (Yu et al., 2005, Mol Cells 19: 328-333). Heat Shock Factors (HSF) and Heat Shock Proteins (HSP) are activated by heat stress and act as chaperones in a similar role to dehydrins in cold and dry stress (Yu et al., 2005, Mol Cells 19: 328-333).
Eine Reihe von pflanzenendogenen Signalstoffen, die in die Stresstoleranz bzw. die Pathogenabwehr involviert sind, sind bereits bekannt. Zu nennen sind hier A number of plant endogenous signaling substances involved in stress tolerance and pathogen defense are already known. To call here are
beispielsweise Salicylsäure, Benzoesäure, Jasmonsäure oder Ethylen [Biochemistry and Molecular Biology of Plants, S. 850-929, American Society of Plant Physiologists, Rockville, Maryland, eds. Buchanan, Gruissem, Jones, 2000]. Einige dieser for example, salicylic acid, benzoic acid, jasmonic acid or ethylene [Biochemistry and Molecular Biology of Plants, pp. 850-929, American Society of Plant Physiologists, Rockville, Maryland, eds. Buchanan, Gruissem, Jones, 2000]. Some of these
Substanzen oder deren stabile synthetische Derivate und abgeleitete Strukturen sind auch bei externer Applikation auf Pflanzen oder Saatgutbeizung wirksam und aktivieren Abwehrreaktionen, die eine erhöhte Stress- bzw. Pathogentoleranz der Pflanze zur Folge haben [Sembdner, and Parthier, 1993, Ann. Rev. Plant Physiol. Plant Mol. Biol. 44: 569-589]. Es ist weiter bekannt, dass chemische Substanzen die Toleranz von Pflanzen gegen abioti sehen Stress erhöhen können. Derartige Substanzen werden dabei entweder durch Saatgut-Beizung, durch Blattspritzung oder durch Bodenbehandung appliziert. So wird eine Erhöhung der abioti sehen Stresstoleranz von Kulturpflanzen durch Behandlung mit Elicitoren der Systemic Acquired Resistance (SAR) oder Substances or their stable synthetic derivatives and derived structures are also effective in external application to plants or seed dressing and activate defense reactions that result in an increased stress or pathogen tolerance of the plant [Sembdner, and Parthier, 1993, Ann. Rev. Plant Physiol. Plant Mol. Biol. 44: 569-589]. It is also known that chemical substances can increase the tolerance of plants to abiotic stress. Such substances are applied either by seed dressing, by foliar spraying or by soil treatment. Thus, an increase in the abioti stress tolerance of crops by treatment with systemic acquired resistance (SAR) or elicitors
Abscisinsäure-Derivaten beschrieben (Schading and Wei, WO200028055; Churchill et al., 1998, Plant Growth Regul 25: 35-45). Desweiteren wurden Effekte von Abscisic acid derivatives (Schading and Wei, WO200028055, Churchill et al., 1998, Plant Growth Regul 25: 35-45). Furthermore, effects of
Wachstumsregulatoren auf die Stresstoleranz von Kulturpflanzen beschrieben (Morrison and Andrews, 1992, J Plant Growth Regul 1 1 : 1 13-1 17, RD-259027). In diesem Zusammenhang ist ebenfalls bekannt, dass ein wachstumsregulierendes Naphthylsulfonamid (4-Brom-N-(pyridin-2-ylmethyl)naphthalin-1 -Sulfonamid) die Keimung von Pflanzensamen in der gleichen Weise wie Abscisinsäure beeinflusst (Park et al. Science 2009, 324, 1068-1071 ). Außerdem ist bekannt, dass ein weiteres Naphthylsulfonamid, N-(6-aminohexyl)-5-chlornaphthalin-1 -Sulfonamid, den Calcium- Spiegel in Pflanzen beeinflusst, die einem Kälteschock ausgesetzt wurden (Cholewa et al. Can. J. Botany 1997, 75, 375-382). Growth regulators on the stress tolerance of crops described (Morrison and Andrews, 1992, J Plant Growth Regul 1 1: 1 13-1 17, RD-259027). In this context, it is also known that a growth-regulating Naphthylsulfonamide (4-bromo-N- (pyridin-2-ylmethyl) -naphthalene-1-sulfonamide) affects the germination of plant seeds in the same manner as abscisic acid (Park et al., Science 2009, 324, 1068-1071). In addition, it is known that another naphthylsulfonamide, N- (6-aminohexyl) -5-chloronaphthalene-1-sulfonamide, affects calcium levels in plants that have been cold shocked (Cholewa et al., Can. J. Botany 1997, Vol. 75, 375-382).
Auch bei Anwendung von Fungiziden, insbesondere aus der Gruppe der Strobilurine oder der Succinat Dehydrogenase Inhibitoren werden ähnliche Effekte beobachtet, die häufig auch mit einer Ertragssteigerung einhergehen (Draber et al., DE3534948, Bartlett et al., 2002, Pest Manag Sei 60: 309). Es ist ebenfalls bekannt, dass das Herbizid Glyphosat in niedriger Dosierung das Wachstum einiger Pflanzenarten stimuliert (Cedergreen, Env. Pollution 2008, 156, 1099). Bei osmotischem Stress ist eine Schutzwirkung durch Applikation von Osmolyten wie z.B. Glycinbetain oder deren biochemischen Vorstufen, z.B. Cholin-Derivate Similar effects are observed even when using fungicides, in particular from the group of strobilurins or succinate dehydrogenase inhibitors, which often also result in increased yields (Draber et al., DE3534948, Bartlett et al., 2002, Pest Management, 60: 309 ). It is also known that the low dose herbicide glyphosate stimulates the growth of some plant species (Cedergreen, Env. Pollution 2008, 156, 1099). At osmotic stress, a protective effect is provided by the application of osmolytes, e.g. Glycine betaine or its biochemical precursors, e.g. Choline derivatives
beobachtet worden (Chen et al., 2000, Plant Cell Environ 23: 609-618, Bergmann et al., DE4103253). Auch die Wirkung von Antioxidantien wie z.B Naphtole und Xanthine zur Erhöhung der abiotischen Stresstoleranz in Pflanzen wurde bereits beschrieben (Bergmann et al., DD277832, Bergmann et al., DD277835). Die molekularen Ursachen der Anti-Stress-Wirkung dieser Substanzen sind jedoch weitgehend unbekannt. (Chen et al., 2000, Plant Cell Environ 23: 609-618, Bergmann et al., DE4103253). The action of antioxidants such as naphtols and xanthines to increase the abiotic stress tolerance in plants has also been described (Bergmann et al., DD277832, Bergmann et al., DD277835). However, the molecular causes of the anti-stress effects of these substances are largely unknown.
Es ist weiter bekannt, dass die Toleranz von Pflanzen gegenüber abiotischem Stress durch eine Modifikation der Aktivität von endogenen Poly-ADP-ribose Polymerasen (PA P) oder Poly-(ADP-ribose) glycohydrolasen (PARG) erhöht werden kann (de Block et al., The Plant Journal, 2004, 41 , 95; Levine et al., FEBS Lett. 1998, 440, 1 ; WO0004173; WO04090140). It is further known that the tolerance of plants to abiotic stress can be increased by a modification of the activity of endogenous poly-ADP-ribose polymerases (PA P) or poly (ADP-ribose) glycohydrolases (PARG) (de Block et al , The Plant Journal, 2004, 41, 95; Levine et al., FEBS Lett. 1998, 440, 1, WO0004173, WO04090140).
Somit ist bekannt, dass Pflanzen über mehrere endogene Reaktionsmechanismen verfügen, die eine wirksame Abwehr gegenüber verschiedensten Schadorganismen und/oder natürlichem abiotischem Stress bewirken können. Thus, it is known that plants have several endogenous reaction mechanisms that can effectively prevent various harmful organisms and / or natural abiotic stress.
Da sich die ökologischen und ökonomischen Anforderungen an moderne As the environmental and economic demands on modern
Pflanzenbehandlungsmittel laufend erhöhen, beispielsweise was Toxizität, Selektivität, Aufwandmenge, Rückstandsbildung und günstige Herstellbarkeit angeht, besteht die ständige Aufgabe, neue Pflanzenbehandlungsmittel zu entwickeln, die zumindest in Teilbereichen Vorteile gegenüber den bekannten aufweisen. Daher bestand die Aufgabe der vorliegenden Erfindung darin, weitere Verbindungen bereitzustellen, die die Toleranz gegenüber abiotischem Stress in Pflanzen erhöhen, insbesondere eine Stärkung des Pflanzenwachstums bewirken und/oder zur Erhöhung des Pflanzenertrags beitragen. Gegenstand der vorliegenden Erfindung ist demnach die Verwendung substituierter 1 - (Arylethinyl)-, l -(Heteroarylethinyl)-, 1 -(Heterocyclylethinyl)- und 1 -(Cyloalkenylethinyl)- bicycloalkanole der allgemeinen Formel (I) oder deren Salze zur Erhöhung der Stresstoleranz in Pflanzen gegenüber abiotischem Stress und/oder zur Erhöhung des Pflanzenertrags. Continuously increase plant protection products, for example, toxicity, selectivity, Applied rate, residue formation and cheap manufacturability, there is the constant task of developing new plant treatment agents that have advantages over the known at least in some areas. Therefore, the object of the present invention was to provide further compounds which increase the tolerance to abiotic stress in plants, in particular to effect a strengthening of plant growth and / or contribute to increasing the plant yield. The present invention accordingly provides for the use of substituted 1 - (arylethynyl) -, 1 - (heteroarylethynyl) -, 1 - (heterocyclylethynyl) - and 1 - (cycloalkenylethynyl) - bicycloalkanols of the general formula (I) or salts thereof for increasing the stress tolerance in plants to abiotic stress and / or to increase plant yield.
wobei in which
[X-Y] für die Gruppierungen [X-Y] for the groupings
[X-Y]1 [X-Y]2 und [X-Y] steht, [XY] 1 [XY] 2 and [XY],
Q für die Gruppierungen Q-1 bis Q-6 Q for the groupings Q-1 to Q-6
Q-1 Q-2 Q-3  Q-1 Q-2 Q-3
Q-4 , Q-5 und Q-6 steht, wobei R13, R14, R15, R16, R17, R18, R19, R20, R23, R24, R25, R26, R28, R29, R30, R31, R32, R34, R35 und R36 sowie A1 bis A9 jeweils die Bedeutung gemäß der nachstehenden Definitionen haben und wobei der Pfeil für eine Bindung zur jeweiligen Gruppierung C-R6 in der allgemeinen Formel (I) steht, Q-4, Q-5 and Q-6, wherein R 13 , R 14 , R 15 , R 16 , R 17 , R 18 , R 19 , R 20 , R 23 , R 24 , R 25 , R 26 , R 28 , R 29 , R 30 , R 31 , R 32 , R 34 , R 35 and R 36 and A 1 to A 9 are each as defined below and wherein the arrow indicates a bond to the respective grouping CR 6 in the general formula (I) stands,
R1 für Alkyl, Cycloalkyl, Cycloalkenyl, Aikenyl, Aikinyl, Aikenylalkyl, Alkinylalkyl, Alkoxyalkyi, Hydroxyalkyl, Haioalkyl, Haloaikenyl, Haloalkinyl, Haloaikoxyalkyi, Alkoxyhaloalkyl, Haloalkoxyhaloalkyl, Alkylthioalkyl, Haloalkylthioalkyl, Aryl, Heteroaryl, Heterocyclyl steht, R 1 is alkyl, cycloalkyl, cycloalkenyl, akenyl, aikinyl, aikylalkyl, alkynylalkyl, alkoxyalkyi, hydroxyalkyl, haloalkyl, haloaikenyl, haloalkynyl, haloalkoxyalkyl, alkoxyhaloalkyl, haloalkoxyhaloalkyl, alkylthioalkyl, haloalkylthioalkyl, aryl, heteroaryl, heterocyclyl,
R2, R3 und R4 unabhängig voneinander für Wasserstoff, Alkyl, Aryl, Heteroaryl, R 2 , R 3 and R 4 independently of one another represent hydrogen, alkyl, aryl, heteroaryl,
Heterocyclyl, Cycloalkyl, Cycloalkenyl, Aikenyl, Aikinyl, Aikenylalkyl, Alkinylalkyl, Alkoxyalkyi, Hydroxyalkyl, Haioalkyl, Haloaikenyl, Haloalkinyl, Haloaikoxyalkyi, Alkoxyhaloalkyl, Haloalkoxyhaloalkyl, Alkylthioalkyl, Haloalkylthioalkyl stehen,  Heterocyclyl, cycloalkyl, cycloalkenyl, aikyl, aikinyl, aikylalkyl, alkynylalkyl, alkoxyalkyi, hydroxyalkyl, haloalkyl, haloaikenyl, haloalkynyl, haloalkoxyalkyl, alkoxyhaloalkyl, haloalkoxyhaloalkyl, alkylthioalkyl, haloalkylthioalkyl,
R5 für Hydroxy, Alkoxy, Aryloxy, Cycloalkyloxy, Alkenyloxy, Alkenylalkyloxy, R 5 is hydroxy, alkoxy, aryloxy, cycloalkyloxy, alkenyloxy, alkenylalkyloxy,
Alkoxyalkyloxy, Alkylcarbonyloxy, Arylcarbonyloxy, Heteroarylcarbonyloxy, Cycloalkylcarbonyloxy, Alkoxycarbonyloxy, Allyloxycarbonyloxy,  Alkoxyalkyloxy, alkylcarbonyloxy, arylcarbonyloxy, heteroarylcarbonyloxy, cycloalkylcarbonyloxy, alkoxycarbonyloxy, allyloxycarbonyloxy,
Aryloxyalkyloxy, Arylalkyloxy, Alkoxyalkoxyalkyloxy, Alkylthioalkyloxy,  Aryloxyalkyloxy, arylalkyloxy, alkoxyalkoxyalkyloxy, alkylthioalkyloxy,
Trialkylsilyloxy, Alkyl(Bis-alkyl)silyloxy, Alkyl(Bis-Aryl)silyloxy, Aryl(Bis- alkyl)silyloxy, Cycloalkyl(Bis-alkyl)silyloxy, Halo(Bis-alkyl)silyloxy,  Trialkylsilyloxy, alkyl (bis-alkyl) silyloxy, alkyl (bis-aryl) silyloxy, aryl (bis-alkyl) silyloxy, cycloalkyl (bis-alkyl) silyloxy, halo (bis-alkyl) silyloxy,
Trialkylsilylalkoxyalkyloxy steht, für Nitro, Amino, Hydroxy, Hydrothio, Thiocyanato, Isothiocyanato, Halogen, Alkyl, Cycloalkyl, Alkenyl, Cycloalkenyl, Alkinyl, Arylalkinyl, Trialkylsilylalkinyl, Aryl, Arylalkyl, Arylalkoxy, Heteroaryl, Haloalkyl, Halocycloalkyl, Haloalkenyl, Alkoxy, Haloalkoxy, Aryloxy, Heteroaryloxy, Cycloalkyloxy, Cycloalkylalkoxy, Alkenyloxy, Alkinylalkyloxy, Hydroxyalkyl, Alkoxyalkyl, Aryloxy alkyl, Trialkylsilylalkoxyalkyloxy stands, for nitro, amino, hydroxy, hydrothio, thiocyanato, isothiocyanato, halogen, alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl, arylalkynyl, trialkylsilylalkynyl, aryl, arylalkyl, arylalkoxy, heteroaryl, haloalkyl, halocycloalkyl, haloalkenyl, alkoxy, haloalkoxy, aryloxy, heteroaryloxy , Cycloalkyloxy, cycloalkylalkoxy, alkenyloxy, alkynylalkyloxy, hydroxyalkyl, alkoxyalkyl, aryloxyalkyl,
Heteroaryloxyalkyl, Alkylthio, Haloalkylthio, Alkoxycarbonylalkylthio, Arylthio, Cycloalkylthio, Heteroarylthio, Alkylthioalkyl, Alkylamino, Bisalkylamino, Alkenylamino, Cycloalkylamino, Alkylcarbonylamino, Cycloalkylcarbonylamino, Arylcarbonylamino, Heteroarylcarbonylamino, Formylamino, Hetaryloxyalkyl
Haloalkylcarbonylamino, Alkoxycarbonylamino, Alkylaminocarbonylamino, Alkyl(Alkyl-)aminocarbonylamino, Alkylsulfonylamino, Cycloalkylsulfonylamino, Arylsulfonylamino, Hetarylsulfonylamino, Sulfonylhaloalkylamino, Haloalkylcarbonylamino, alkoxycarbonylamino, alkylaminocarbonylamino, alkyl (alkyl) aminocarbonylamino, alkylsulfonylamino, cycloalkylsulfonylamino, arylsulfonylamino, hetarylsulfonylamino, sulfonylhaloalkylamino,
Aminoalkylsulfonyl, Aminohaloalkylsulfonyl, Alkylaminosulfonyl, Aminoalkylsulfonyl, aminohaloalkylsulfonyl, alkylaminosulfonyl,
Bisalkylaminosulfonyl, Cycloalkylaminosulfonyl, Haloalkylaminosulfonyl, Heteroarylaminosulfonyl, Arylaminosulfonyl, Arylalkylaminosulfonyl, Bisalkylaminosulfonyl, cycloalkylaminosulfonyl, haloalkylaminosulfonyl, heteroarylaminosulfonyl, arylaminosulfonyl, arylalkylaminosulfonyl,
Alkylsulfonyl, Cycloalkylsulfonyl, Arylsulfonyl, Alkylsulfinyl, Cycloalkylsulfinyl, Arylsulfinyl, N,S-Dialkylsulfonimidoyl, S-Alkylsulfonimidoyl, Alkylsulfonyl, cycloalkylsulfonyl, arylsulfonyl, alkylsulfinyl, cycloalkylsulfinyl, arylsulfinyl, N, S-dialkylsulfonimidoyl, S-alkylsulfonimidoyl,
Alkylsulfonylaminocarbonyl, Cycloalkylsulfonylaminocarbonyl, Alkylsulfonylaminocarbonyl, cycloalkylsulfonylaminocarbonyl,
Arylalkylcarbonylamino, Cycloalkylalkylcarbonylamino, Arylalkylcarbonylamino, cycloalkylalkylcarbonylamino,
Heteroarylcarbonylamino, Alkoxyalkylcarbonylamino, Heteroarylcarbonylamino, alkoxyalkylcarbonylamino,
Hydroxyaikylcarbonylamino, Alkoxy carbonylaminoalkylcarbonylamino, Cyano, Cyanoalkyl, Hydroxycarbonyl, Alkoxy carbonyl, Cycloalkoxycarbonyl,  Hydroxyalkylcarbonylamino, alkoxycarbonylaminoalkylcarbonylamino, cyano, cyanoalkyl, hydroxycarbonyl, alkoxycarbonyl, cycloalkoxycarbonyl,
Cycloalkylalkoxycarbonyl, Aryloxycarbonyl, Arylalkoxycarbonyl, Cycloalkylalkoxycarbonyl, aryloxycarbonyl, arylalkoxycarbonyl,
Alkenyloxycarbonyl, Alkinyloxycarbonyl, Haloalkyloxycarbonyl, Alkenyloxycarbonyl, alkynyloxycarbonyl, haloalkyloxycarbonyl,
Alkoxyalkoxycarbonyl, Alkenyloxyalkoxycarbonyl, Alkylaminoalkoxycarbonyl, Trisalkylsilyloxyalkoxycarbonyl, Bis- Alkylaminoalkoxycarbonyl, Alkoxyalkoxycarbonyl, alkenyloxyalkoxycarbonyl, alkylaminoalkoxycarbonyl, trisalkylsilyloxyalkoxycarbonyl, bis-alkylaminoalkoxycarbonyl,
Alkyl(alkyl)aminoalkoxycarbonyl, Cyanoalkoxycarbonyl, Heterocyclyl-N- alkoxycarbonyl, Heteroaryloxycarbonyl, Heteroarylalkoxycarbonyl, Alkyl (alkyl) aminoalkoxycarbonyl, cyanoalkoxycarbonyl, heterocyclyl-N-alkoxycarbonyl, heteroaryloxycarbonyl, heteroarylalkoxycarbonyl,
Heterocyclylalkoxy carbonyl, Heterocyclyloxy carbonyl, Alkenylalkoxycarbonyl, Alkinylalkoxy carbonyl, Arylalkinyloxycarbonyl, Arylalkenyloxy carbonyl, Heterocyclylalkoxycarbonyl, heterocyclyloxycarbonyl, alkenylalkoxycarbonyl, alkynylalkoxycarbonyl, arylalkynyloxycarbonyl, arylalkenyloxycarbonyl,
Aminocarbonyl, Alkylaminocarbonyl, Bisalkylaminocarbonyl, Aminocarbonyl, alkylaminocarbonyl, bisalkylaminocarbonyl,
Alkyl(Alkyl)aminocarbonyl, Alkyl(Alkoxy)aminocarbonyl, Alkenylaminocarbonyl, Cycloalkylaminocarbonyl, Arylaminocarbonyl, Arylalkylaminocarbonyl, Alkyl (alkyl) aminocarbonyl, alkyl (alkoxy) aminocarbonyl, alkenylaminocarbonyl, cycloalkylaminocarbonyl, arylaminocarbonyl, arylalkylaminocarbonyl,
Heteroarylalkylaminocarbonyl, Cyanoalkylaminocarbonyl, Haloalkylaminocarbonyl, Alkinylalkylaminocarbonyl, Heteroarylalkylaminocarbonyl, cyanoalkylaminocarbonyl, Haloalkylaminocarbonyl, alkynylalkylaminocarbonyl,
Alkoxycarbonylaminocarbonyl, Arylalkoxycarbonylaminocarbonyl, Alkoxycarbonylaminocarbonyl, arylalkoxycarbonylaminocarbonyl,
Hydroxycarbonylalkyl, Alkoxycarbonylalkyl, Cycloalkoxycarbonylalkyl, Hydroxycarbonylalkyl, alkoxycarbonylalkyl, cycloalkoxycarbonylalkyl,
Cycloalkylalkoxycarbonylalkyl, Alkenyloxycarbonylalkyl, Arylalkoxycarbonylalkyl, Alkylaminocarbonylalkyl, Aminocarbonylalkyl, Bisalkylaminocarbonylalkyl, Cycloalkylaminocarbonylalkyl, Arylalkylaminocarbonylalkyl, Cycloalkylalkoxycarbonylalkyl, alkenyloxycarbonylalkyl, arylalkoxycarbonylalkyl, alkylaminocarbonylalkyl, aminocarbonylalkyl, bisalkylaminocarbonylalkyl, cycloalkylaminocarbonylalkyl, arylalkylaminocarbonylalkyl,
Heteroarylalkylaminocarbonylalkyl, Cyanoalkylaminocarbonylalkyl, Heteroarylalkylaminocarbonylalkyl, cyanoalkylaminocarbonylalkyl,
Haloalkylaminocarbonylalkyl, Alkinylalkylaminocarbonylalkyl, Haloalkylaminocarbonylalkyl, alkynylalkylaminocarbonylalkyl,
Cycloalkylalkylaminocarbonylalkyl, Alkoxycarbonylaminocarbonylalkyl, Cycloalkylalkylaminocarbonylalkyl, alkoxycarbonylaminocarbonylalkyl,
Arylalkoxycarbonylaminocarbonylalkyl, Alkoxycarbonylalkylaminocarbonyl, Hydroxycarbonylalkylaminocarbonyl, Arylalkoxycarbonylalkylaminocarbonyl, Aminocarbonylalkylaminocarbonyl, Alkylaminocarbonylalkylaminocarbonyl, Cycloalkylaminocarbonylalkylaminocarbonyl, Cycloalkylalkylaminocarbonyl, Cycloalkylalkylaminocarbonylalkyl, Arylalkoxycarbonylaminocarbonylalkyl, alkoxycarbonylalkylaminocarbonyl, hydroxycarbonylalkylaminocarbonyl, arylalkoxycarbonylalkylaminocarbonyl, aminocarbonylalkylaminocarbonyl, alkylaminocarbonylalkylaminocarbonyl, cycloalkylaminocarbonylalkylaminocarbonyl, cycloalkylalkylaminocarbonyl, cycloalkylalkylaminocarbonylalkyl,
Cycloalkylalkylaminocarbonylalkylaminocarbonyl, Alkenylalkylaminocarbonyl, Alkenylaminocarbonylalkyl, Alkenylalkylaminocarbonylalkyl, Alkylcarbonyl, Cycloalkylcarbonyl, Arylcarbonyl, Formyl, Hydroxyiminomethyl,  Cycloalkylalkylaminocarbonylalkylaminocarbonyl, alkenylalkylaminocarbonyl, alkenylaminocarbonylalkyl, alkenylalkylaminocarbonylalkyl, alkylcarbonyl, cycloalkylcarbonyl, arylcarbonyl, formyl, hydroxyiminomethyl,
Aminoiminomethyl, Alkoxyiminomethyl, Alkylaminoiminomethyl, Aminoiminomethyl, alkoxyiminomethyl, alkylaminoiminomethyl,
Diaikylaminoiminomethyl, Cycioaikoxyiminomethyl, Cycloalkylalkoximinomethyl, Aryloximinomethyl, Arylalkoxyiminomethyl, Arylalkylaminoiminomethyl, Diaikylaminoiminomethyl, Cycioaikoxyiminomethyl, Cycloalkylalkoximinomethyl, Aryloximinomethyl, Arylalkoxyiminomethyl, Arylalkylaminoiminomethyl,
Alkenyloxyiminomethyl, Arylaminoiminomethyl, Arylsulfonylaminoiminomethyl, Heteroarylalkyl, Heterocyclylalkyl, Hydroxycarbonylheterocyclyl, Alkenyloxyiminomethyl, arylaminoiminomethyl, arylsulfonylaminoiminomethyl, heteroarylalkyl, heterocyclylalkyl, hydroxycarbonylheterocyclyl,
Alkoxycarbonylheterocyclyl, Alkenyloxycarbonylheterocyclyl, Alkoxycarbonylheterocyclyl, alkenyloxycarbonylheterocyclyl,
Alkenylalkoxycarbonylheterocyclyl, Arylalkoxycarbonylheterocyclyl, Alkenylalkoxycarbonylheterocyclyl, arylalkoxycarbonylheterocyclyl,
Cycloalkoxycarbonylheterocyclyl, Cycloalkylalkoxycarbonylheterocyclyl, Aminocarbonylheterocyclyl, Alkylaminocarbonylheterocyclyl, Bis- Alkylaminocarbonylheterocyclyl, Cycloalkylaminocarbonylheterocyclyl, Cycloalkoxycarbonylheterocyclyl, cycloalkylalkoxycarbonylheterocyclyl, aminocarbonylheterocyclyl, alkylaminocarbonylheterocyclyl, bis-alkylaminocarbonylheterocyclyl, cycloalkylaminocarbonylheterocyclyl,
Arylalkylaminocarbonylheterocyclyl, Alkenylaminocarbonylheterocyclyl, Arylalkylaminocarbonylheterocyclyl, alkenylaminocarbonylheterocyclyl,
Hydroxycarbonylheterocyclylalkyl, Alkoxycarbonylheterocyclylalkyl, Hydroxycarbonylheterocyclylalkyl, alkoxycarbonylheterocyclylalkyl,
Hydroxycarbonylcycloalkylalkyl, Alkoxycarbonylcycloalkylalkyl, Hydroxycarbonylcycloalkylalkyl, alkoxycarbonylcycloalkylalkyl,
Hydroxyaminocarbonyl, Alkoxyaminocarbonyl, Arylalkoxyaminocarbonyl, Heterocyclyl, Alkylcarbonyloxy, Arylcarbonyloxy, Heteroarylcarbonyloxy, Cycloalkylcarbonyloxy, Alkoxycarbonyloxy, Alkenyloxycarbonyloxy, Hydroxyaminocarbonyl, alkoxyaminocarbonyl, arylalkoxyaminocarbonyl, heterocyclyl, alkylcarbonyloxy, arylcarbonyloxy, heteroarylcarbonyloxy, cycloalkylcarbonyloxy, alkoxycarbonyloxy, alkenyloxycarbonyloxy,
Aminosulfonyl, Alkoxyalkylaminocarbonyl, Alkoxycarbonylheterocyclyl-N- carbonyl, Alkoxycarbonylalkylheterocyclylidenaminocarbonyl,Aminosulfonyl, alkoxyalkylaminocarbonyl, alkoxycarbonylheterocyclyl-N- carbonyl, alkoxycarbonylalkylheterocyclylidenaminocarbonyl,
Alkoxycarbonylheterocyclylidenalkylaminocarbonyl, Alkoxycarbonylheterocyclylidenalkylaminocarbonyl,
Alkoxycarbonylalkyl(alkyl)aminocarbonyl,  Alkoxycarbonylalkyl (alkyl) aminocarbonyl,
Alkoxycarbonylcycloalkylidenaminocarbonyl, Heterocyclyl-N-carbonyl sieht,  Alkoxycarbonylcycloalkylidene-aminocarbonyl, heterocyclyl-N-carbonyl,
R7, R8, R9, R10, R11 und R12 unabhängig voneinander für Wasserstoff, Alkyl, Cycloalkyl, Alkenyl, Alkenylalkyl, Alkoxyalkyl, Hydroxyalkyl, Haloalkyl, Haloalkenyi, R 7 , R 8 , R 9 , R 10 , R 11 and R 12 are independently hydrogen, alkyl, cycloalkyl, alkenyl, alkenylalkyl, alkoxyalkyl, hydroxyalkyl, haloalkyl, haloalkenyl,
Haloalkoxyalkyl, Alkoxyhaloalkyl, Haloalkoxyhaloalkyl, Alkoxy, Alkylthio, Aikylamino, Halogen, Amino, Aryl, Heteroaryl, Heterocyclyl, Arylthio,  Haloalkoxyalkyl, alkoxyhaloalkyl, haloalkoxyhaloalkyl, alkoxy, alkylthio, aikylamino, halogen, amino, aryl, heteroaryl, heterocyclyl, arylthio,
Cycloalkylthio, Heterocyclylthio, Alkylsulfinyl, Arylsulfinyl, Heteroarylsulfinyl, Cycloalkylthio, heterocyclylthio, alkylsulfinyl, arylsulfinyl, heteroarylsulfinyl,
Cycloalkylsulfinyl, Heterocyclylsulfinyl, Alkylsulfonyl, Arylsulfonyl, Cycloalkylsulfinyl, heterocyclylsulfinyl, alkylsulfonyl, arylsulfonyl,
Heteroarylsulfonyl, Cycloalkylsulfonyl, Heterocyclylsulfonyl stehen, wobei mindestens eine der Gruppen R7, R8, R9, R10, R11 und R12 nicht für Wasserstoff steht und Heteroarylsulfonyl, cycloalkylsulfonyl, heterocyclylsulfonyl, wherein at least one of the groups R 7 , R 8 , R 9 , R 10 , R 11 and R 12 is not hydrogen and
R3 und R4 mit dem Atom, an das sie gebunden sind, eine exo-Alkylidengruppe oder einen vollständig gesättigten, gegebenenfalls durch O (Sauerstoff), S R 3 and R 4 with the atom to which they are attached, an exo-alkylidene group or a fully saturated, optionally substituted by O (oxygen), S
(Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und (Sulfur) or a group NH, NR 37 interrupted and
gegebenenfalls weiter substituierten 3 bis 6-gliedrigen Ring bilden,  optionally form further substituted 3 to 6-membered ring,
R1 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 1 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
R1 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel), S=0, S(=0)2 oder eine Gruppierung N-H, N+-R37(-0~), N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, R 1 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally by O (oxygen), S (sulfur), S = 0, S (= 0) 2 or a group NH, N + -R 37 (-0 ~), NR 37 and optionally further interrupted form substituted 3 to 7-membered ring,
R3 und R7 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel), S=0, S(=0)2 oder eine Gruppierung N-H, N+-R37(-0"), N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R3 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel), S=0, S(=0)2 oder eine Gruppierung N-H, N+-R37(-0"), N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, R 3 and R 7 with the atoms to which they are attached, a fully saturated or partially saturated, optionally by O (oxygen), S (sulfur), S = 0, S (= 0) 2 or a group NH, N + R 37 (-0 " ), NR 37 form interrupted and optionally further substituted 5 to 7-membered ring, R 3 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally by O (oxygen), S (sulfur), S = 0, S (= 0) 2 or a group NH, N + R 37 (-0 " ), NR 37 form interrupted and optionally further substituted 3 to 7-membered ring,
R1 und R3 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel), S=0, S(=0)2 oder eine Gruppierung N-H, N+-R37(-0 ), N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 1 and R 3 with the atoms to which they are attached, a fully saturated or partially saturated, optionally by O (oxygen), S (sulfur), S = 0, S (= 0) 2 or a group NH, N + R 37 (-0), NR 37 form interrupted and optionally further substituted 5 to 7-membered ring,
R7 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel), S=0, S(=0)2 oder eine Gruppierung N-H, N+-R37(-0 ), N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 7 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally by O (oxygen), S (sulfur), S = 0, S (= 0) 2 or a group NH, N + R 37 (-0), NR 37 form interrupted and optionally further substituted 5 to 7-membered ring,
R3 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel S=0, S(=0)2 oder eine Gruppierung N-H, N+-R37(-0"), N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, R 3 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally by O (oxygen), S (sulfur S = 0, S (= 0) 2 or a group NH, N + -R 37 (-0 " ), NR 37 form interrupted and optionally further substituted 3 to 7-membered ring,
R7 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel), S=0, S(=0)2 oder eine Gruppierung N-H, N+-R37(-0"), N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, R 7 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally by O (oxygen), S (sulfur), S = 0, S (= 0) 2 or a group NH, N + R 37 (-0 " ), NR 37 form interrupted and optionally further substituted 3 to 7-membered ring,
R13, R14, R15 und R16 unabhängig voneinander für Wasserstoff, Halogen, Nitro, Amino, Cyano, Alkyl, Aryl, Heteroaryl, Cycloalkyl, Cycloalkenyl, Alkenyl, Alkinyl, Alkenylalkyl, Alkinylalkyl, Hydroxy, Alkoxy, Alkoxyalkoxy, Alkoxyalkyl, R 13 , R 14 , R 15 and R 16 are each independently hydrogen, halogen, nitro, amino, cyano, alkyl, aryl, heteroaryl, cycloalkyl, cycloalkenyl, alkenyl, alkynyl, alkenylalkyl, alkynylalkyl, hydroxy, alkoxy, alkoxyalkoxy, alkoxyalkyl,
Hydroxyalkyl, Haloalkoxy, Haloalkyl, Haloalkenyl, Haloalkinyl, Haloalkoxyalkyl, Hydroxyalkyl, haloalkoxy, haloalkyl, haloalkenyl, haloalkynyl, haloalkoxyalkyl,
Alkoxyhaloalkyl, Haloalkoxyhaloalkyl, Hydrothio, Alkylthio, Haloalkylthio, Alkylthioalkyl, Haloalkylthioalkyl, Alkylamino, Bisalkylamino, Alkenylamino, Cycloalkylamino, Alkylcarbonylamino, Cycloalkylcarbonylamino, Alkoxyhaloalkyl, haloalkoxyhaloalkyl, hydrothio, alkylthio, haloalkylthio, alkylthioalkyl, haloalkylthioalkyl, alkylamino, bisalkylamino, alkenylamino, cycloalkylamino, alkylcarbonylamino, cycloalkylcarbonylamino,
Arylcarbonylamino, Heteroarylcarbonylamino, Formylamino, Haloalkylcarbonylamino, Alkoxycarbonylamino, Alkylaminocarbonylamino, Alkyl(Alkyl-)aminocarbonylamino, Alkylsulfonylamino, Cycloalkylsulfonylamino, Arylsulfonylamino, Hetarylsulfonylamino, Suifonylhaloalkylamino, Arylcarbonylamino, heteroarylcarbonylamino, formylamino, Haloalkylcarbonylamino, alkoxycarbonylamino, alkylaminocarbonylamino, alkyl (alkyl) aminocarbonylamino, alkylsulfonylamino, cycloalkylsulfonylamino, arylsulfonylamino, hetarylsulfonylamino, suifonylhaloalkylamino,
Aminoalkylsulfonyl, Aminohaloalkylsulfonyl, Alkylaminosulfonyl,  Aminoalkylsulfonyl, aminohaloalkylsulfonyl, alkylaminosulfonyl,
Bisalkylaminosulfonyl, Cycloalkylaminosulfonyl, Haloalkylaminosulfonyl, Heteroarylaminosulfonyl, Arylaminosulfonyl, Arylalkylaminosulfonyl,  Bisalkylaminosulfonyl, cycloalkylaminosulfonyl, haloalkylaminosulfonyl, heteroarylaminosulfonyl, arylaminosulfonyl, arylalkylaminosulfonyl,
Alkylsulfonyl, Cycloalkylsulfonyi, Arylsulfonyl, Hydroxycarbonyl, Aikoxycarbonyl, Cycloalkoxycarbonyl, Cycloalkylalkoxycarbonyl, Aryloxycarbonyl,  Alkylsulfonyl, cycloalkylsulfonyi, arylsulfonyl, hydroxycarbonyl, aikoxycarbonyl, cycloalkoxycarbonyl, cycloalkylalkoxycarbonyl, aryloxycarbonyl,
Arylalkoxycarbonyl, Alkenyloxycarbonyl, Alkinyloxycarbonyl, Aminocarbonyl, Alkylaminocarbonyl, Bisalkylaminocarbonyl, Alkyl(Alkyl)aminocarbonyl,  Arylalkoxycarbonyl, alkenyloxycarbonyl, alkynyloxycarbonyl, aminocarbonyl, alkylaminocarbonyl, bisalkylaminocarbonyl, alkyl (alkyl) aminocarbonyl,
Alkyl(Alkoxy)aminocarbonyl, Alkenylaminocarbonyl, Cycloalkylaminocarbonyl, Arylaminocarbonyl, Arylalkylaminocarbonyl, Heterocyclyl, Arylthio,  Alkyl (alkoxy) aminocarbonyl, alkenylaminocarbonyl, cycloalkylaminocarbonyl, arylaminocarbonyl, arylalkylaminocarbonyl, heterocyclyl, arylthio,
Cycloalkylthio, Heterocyclylthio, Alkylsulfinyl, Arylsulfinyl, Heteroarylsulfinyl, Cycloaikyisulfinyl, Heterocyclyisulfinyl, Heteroarylsulfonyl, Heterocyclyisulfonyl stehen,  Cycloalkylthio, heterocyclylthio, alkylsulfinyl, arylsulfinyl, heteroarylsulfinyl, cycloalkylsulfinyl, heterocyclyisulfinyl, heteroarylsulfonyl, heterocyclyisulfonyl,
A\ A2, A3 und A4 gleich oder verschieden sind und unabhängig voneinander für N A \ A 2 , A 3 and A 4 are the same or different and are independently N
(Stickstoff) oder die Gruppierungen C-H, C-CH3, C-F, C-Cl, C-Br, C-l, C-OCF3, C-OCH3, C-CF3, C-CO2H, C-CO2CH3 stehen, wobei jedoch in keinem Fall mehr als zwei N-Atome benachbart sind, (Nitrogen) or the groupings CH, C-CH 3, CF, C-Cl, C-Br, CI, C-OCF3, C-OCH3, C-CF 3, C-CO2H, C-CO2CH3 are, however, in no more than two N-atoms are adjacent,
R17 und R18 unabhängig voneinander für Wasserstoff, Halogen, Alkyl, Aryl, Heteroaryl, Heterocyclyl, Cycloalkyl, Alkenyl, Alkinyl, Alkoxy, Alkoxyalkyl, Aryloxyalkyl, Haloalkoxy, Haloalkyl, Haloalkoxyalkyl, Alkoxyhaloalkyl, Haloalkoxyhaloalkyl, Alkylthio, Haloalkylthio, Alkylthioalkyl, Hydroxycarbonyl, Aikoxycarbonyl, Cycloalkoxycarbonyl, Cycloalkylalkoxycarbonyl, Aryloxycarbonyl, R 17 and R 18 independently of one another represent hydrogen, halogen, alkyl, aryl, heteroaryl, heterocyclyl, cycloalkyl, alkenyl, alkynyl, alkoxy, alkoxyalkyl, aryloxyalkyl, haloalkoxy, haloalkyl, haloalkoxyalkyl, alkoxyhaloalkyl, haloalkoxyhaloalkyl, alkylthio, haloalkylthio, alkylthioalkyl, hydroxycarbonyl, Aoxycarbonyl, cycloalkoxycarbonyl, cycloalkylalkoxycarbonyl, aryloxycarbonyl,
Arylalkoxycarbonyl, Alkenyloxycarbonyl, Alkinyloxycarbonyl, Aminocarbonyl, Alkylaminocarbonyl, Bisalkylaminocarbonyl, Alkyl(Alkyl)aminocarbonyl,  Arylalkoxycarbonyl, alkenyloxycarbonyl, alkynyloxycarbonyl, aminocarbonyl, alkylaminocarbonyl, bisalkylaminocarbonyl, alkyl (alkyl) aminocarbonyl,
Alkyl(Alkoxy)aminocarbonyl, Alkenylaminocarbonyl, Cycloalkylaminocarbonyl, Arylaminocarbonyl, Arylalkylaminocarbonyl stehen,  Alkyl (alkoxy) aminocarbonyl, alkenylaminocarbonyl, cycloalkylaminocarbonyl, arylaminocarbonyl, arylalkylaminocarbonyl,
A5 für S (Schwefel), O (Sauerstoff) oder die Gruppierungen N-H, N-CH3, N-CH2CH3, N- CH(CH3)2, N-C02t-Bu, N-Aryl, N-Heteroaryl, N-Heterocyclyl steht, R19, R20, R23 und R24 unabhängig voneinander für Wasserstoff, Alkyl, Halogen, Cycloalkyl, Aryl, Heteroaryl, Heterocyclyl, Alkenyl, Alkenylalkyl, Arylalkyl, Alkoxy, Alkoxyalkoxy, Alkoxyalkyl, Hydroxy, Haloalkyl, Haloalkylthio stehen, A 5 for S (sulfur), O (oxygen) or the groupings NH, N-CH 3 , N-CH 2 CH 3 , N-CH (CH 3 ) 2 , N-CO 2 t-Bu, N-aryl, N-heteroaryl , N-heterocyclyl, R 19 , R 20 , R 23 and R 24 are each independently hydrogen, alkyl, halogen, cycloalkyl, aryl, heteroaryl, heterocyclyl, alkenyl, alkenylalkyl, arylalkyl, alkoxy, alkoxyalkoxy, alkoxyalkyl, hydroxy, haloalkyl, haloalkylthio,
R19 und R23 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 19 and R 23 with the atoms to which they are attached form a completely saturated or partially saturated, optionally further substituted 5 to 7-membered ring,
A6, A7 gleich oder verschieden sind und unabhängig voneinander für O (Sauerstoff), S (Schwefel), S=0, S(=0)2, N-H, N+-CH3(-0"), N-OCH3, N-CH3 oder die A 6 , A 7 are the same or different and are independently O (oxygen), S (sulfur), S = O, S (= O) 2 , NH, N + -CH 3 (-O " ), N-OCH 3 , N-CH 3 or the
Gruppierung CR21R22 stehen, wobei jedoch in keinem Fall zwei N-, O- oder S- Atome benachbart sind, und wobei R21 und R22 in der Gruppierung CR21R22 jeweils gleiche oder verschiedene Bedeutungen gemäß der nachstehenden Definition haben und Grouping CR 21 R 22 are, but in any case, two N, O or S atoms are adjacent, and wherein R 21 and R 22 in the group CR 21 R 22 each have the same or different meanings as defined below, and
R21 und R22 unabhängig voneinander für Wasserstoff, Halogen, Alkyl, Aryl, Heteroaryl, Heterocyclyl, Cycloalkyl, Alkenyl, Alkoxy, Alkoxyalkyl, Aryloxyalkyl, Haloalkoxy, Haloalkyl, Haloalkoxyalkyl, Alkoxyhaloalkyl, Haloalkoxyhaloalkyl, Alkylthio, Haloalkylthio, Alkylthioalkyl, Hydroxy carbonyl, Alkoxycarbonyl, R 21 and R 22 are each independently hydrogen, halogen, alkyl, aryl, heteroaryl, heterocyclyl, cycloalkyl, alkenyl, alkoxy, alkoxyalkyl, aryloxyalkyl, haloalkoxy, haloalkyl, haloalkoxyalkyl, alkoxyhaloalkyl, haloalkoxyhaloalkyl, alkylthio, haloalkylthio, alkylthioalkyl, hydroxycarbonyl, alkoxycarbonyl .
Cycloalkoxycarbonyl, Cycloalkylalkoxycarbonyl, Aryl oxy carbonyl,  Cycloalkoxycarbonyl, cycloalkylalkoxycarbonyl, aryl oxycarbonyl,
Arylalkoxycarbonyl, Alkenyloxycarbonyl, Alkinyloxy carbonyl, Aminocarbonyl, Alkylaminocarbonyl, Bisalkylaminocarbonyl, Alkyl(Alkyl)aminocarbonyl, Alkyl(Alkoxy)aminocarbonyl, Alkenylaminocarbonyl, Cycloalkylaminocarbonyl, Arylaminocarbonyl, Arylalkylaminocarbonyl, Amino, Alkylamino,  Arylalkoxycarbonyl, alkenyloxycarbonyl, alkynyloxycarbonyl, aminocarbonyl, alkylaminocarbonyl, bisalkylaminocarbonyl, alkyl (alkyl) aminocarbonyl, alkyl (alkoxy) aminocarbonyl, alkenylaminocarbonyl, cycloalkylaminocarbonyl, arylaminocarbonyl, arylalkylaminocarbonyl, amino, alkylamino,
Cycloalkylamino, Bis- Alkylamino stehen,  Cycloalkylamino, bis-alkylamino,
R25, R26, R28 und R29 unabhängig voneinander für Wasserstoff, Alkyl, Halogen, R 25 , R 26 , R 28 and R 29 independently of one another represent hydrogen, alkyl, halogen,
Cycloalkyl, Aryl, Heteroaryl, Heterocyclyl, Alkenyl, Arylalkyl, Alkoxy,  Cycloalkyl, aryl, heteroaryl, heterocyclyl, alkenyl, arylalkyl, alkoxy,
Alkoxyalkoxy, Alkoxyalkyl, Haloalkyl stehen,  Alkoxyalkoxy, alkoxyalkyl, haloalkyl,
A8 für O (Sauerstoff), S (Schwefel), S=0, S(=0)2, N-H, N+-CH3(-0 ), N-CH3, N-OCH3 oder die Gruppierung CHR27 steht und wobei R27 in der Gruppierung CHR27 die Bedeutung gemäß der nachstehenden Definition hat, R27 für Wasserstoff, Halogen, Alkyl, Aryl, Heteroaryl, Heterocyclyl, Cycloalkyl, Alkenyl, Alkoxy, Alkoxyalkyl, Aryloxyalkyl, Haloalkoxy, Haloalkyl, Alkoxyhaloalkyl, Haloalkoxyhaloalkyl, Alkylthio, Haloalkylthio, Alkylthioalkyl, Hydroxycarbonyl, Alkoxycarbonyl, Cycloalkoxycarbonyl, Arylalkoxycarbonyl, Alkenyloxycarbonyl, Alkinyloxycarbonyl, Aminocarbonyl, Alkylaminocarbonyl, Bisalkylaminocarbonyl, Alkyl(Alkyl)aminocarbonyl, Alkyl(Alkoxy)aminocarbonyl, Alkenylaminocarbonyl, Cycloalkylaminocarbonyl, Arylaminocarbonyl, Arylalkylaminocarbonyl, Amino, Alkylamino, Cycloalkylamino, Bis-Alkylamino steht, A 8 is O (oxygen), S (sulfur), S = O, S (= O) 2 , NH, N + -CH 3 (-O), N-CH 3 , N -OCH 3 or the moiety CHR 27 and wherein R 27 in the grouping CHR 27 has the meaning as defined below, R 27 represents hydrogen, halogen, alkyl, aryl, heteroaryl, heterocyclyl, cycloalkyl, alkenyl, alkoxy, alkoxyalkyl, aryloxyalkyl, haloalkoxy, haloalkyl, alkoxyhaloalkyl, haloalkoxyhaloalkyl, alkylthio, haloalkylthio, alkylthioalkyl, hydroxycarbonyl, alkoxycarbonyl, cycloalkoxycarbonyl, arylalkoxycarbonyl, alkenyloxycarbonyl, alkynyloxycarbonyl , Aminocarbonyl, alkylaminocarbonyl, bisalkylaminocarbonyl, alkyl (alkyl) aminocarbonyl, alkyl (alkoxy) aminocarbonyl, alkenylaminocarbonyl, cycloalkylaminocarbonyl, arylaminocarbonyl, arylalkylaminocarbonyl, amino, alkylamino, cycloalkylamino, bis-alkylamino,
R30, R31, R32, R34, R35 und R36 unabhängig voneinander für Wasserstoff, Alkyl, R 30 , R 31 , R 32 , R 34 , R 35 and R 36 independently of one another are hydrogen, alkyl,
Halogen, Cycloalkyl, Aryl, Heteroaryl, Heterocyclyl, Alkenyl, Alkoxy,  Halogen, cycloalkyl, aryl, heteroaryl, heterocyclyl, alkenyl, alkoxy,
Alkoxyalkoxy, Alkoxyalkyl, Haloalkyl, Alkylthio, Haloalkylthio stehen,  Alkoxyalkoxy, alkoxyalkyl, haloalkyl, alkylthio, haloalkylthio,
A9 für O (Sauerstoff), S (Schwefel), S=0, S(=0)2, N-H, N+-CH3(-0"), N-CH3, N-OCH3 oder die Gruppierung CHR33 steht und wobei R33 in der Gruppierung CHR33 die Bedeutung gemäß der nachstehenden Definition hat und A 9 is O (oxygen), S (sulfur), S = O, S (= O) 2 , NH, N + -CH 3 (-O " ), N-CH 3 , N-OCH 3 or the moiety CHR 33 and wherein R 33 in the grouping CHR 33 has the meaning as defined below, and
R33 für Wasserstoff, Halogen, Alkyl, Aryl, Heteroaryl, Heterocyclyl, Cycloalkyl, Alkenyl, Alkoxy, Alkoxyalkyl, Aryloxyalkyl, Haloalkoxy, Haloalkyl, Alkylthio, Haloalkylthio, Hydroxycarbonyl, Alkoxycarbonyl, Cycloalkoxycarbonyl, Arylalkoxycarbonyl, Alkenyloxycarbonyl, Alkinyloxycarbonyl, Aminocarbonyl, Alkylaminocarbonyl, Bisalkylaminocarbonyl, Alkyl(Alkyl)aminocarbonyl, Alkyl(Alkoxy)aminocarbonyl, Alkenylaminocarbonyl, Cycloalkylaminocarbonyl, Arylaminocarbonyl, R 33 is hydrogen, halogen, alkyl, aryl, heteroaryl, heterocyclyl, cycloalkyl, alkenyl, alkoxy, alkoxyalkyl, aryloxyalkyl, haloalkoxy, haloalkyl, alkylthio, haloalkylthio, hydroxycarbonyl, alkoxycarbonyl, cycloalkoxycarbonyl, arylalkoxycarbonyl, alkenyloxycarbonyl, alkynyloxycarbonyl, aminocarbonyl, alkylaminocarbonyl, bisalkylaminocarbonyl , Alkyl (alkyl) aminocarbonyl, alkyl (alkoxy) aminocarbonyl, alkenylaminocarbonyl, cycloalkylaminocarbonyl, arylaminocarbonyl,
Arylalkylaminocarbonyl, Amino, Alkylamino, Cycloalkylamino, Bis-Alkylamino steht,  Arylalkylaminocarbonyl, amino, alkylamino, cycloalkylamino, bis-alkylamino,
R37 für Alkyl, Aryl, Heteroaryl, Heterocyclyl, Cycloalkyl, Alkenyl, Alkoxy, Alkoxyalkyl, Aryloxyalkyl, Alkoxycarbonyl, Cycloalkoxycarbonyl, Arylalkoxycarbonyl, R 37 is alkyl, aryl, heteroaryl, heterocyclyl, cycloalkyl, alkenyl, alkoxy, alkoxyalkyl, aryloxyalkyl, alkoxycarbonyl, cycloalkoxycarbonyl, arylalkoxycarbonyl,
Alkenyloxycarbonyl, Alkinyloxycarbonyl, Alkylcarbonyl, Cycloalkylcarbonyl, Arylcarbonyl, Heteroarylcarbonyl steht.  Alkenyloxycarbonyl, alkynyloxycarbonyl, alkylcarbonyl, cycloalkylcarbonyl, arylcarbonyl, heteroarylcarbonyl.
Die Verbindungen der allgemeinen Formel (I) können durch Anlagerung einer geeigneten anorganischen oder organischen Säure, wie beispielsweise Mineralsäuren, wie beispielsweise HCl, HBr, H2SO4, H3PO4 oder HNO3, oder organische Säuren, z. B. Carbonsäuren, wie Ameisensäure, Essigsäure, Propionsäure, Oxalsäure, Milchsäure oder Salicylsäure oder Sulfonsäuren, wie zum Beispiel p-Toluolsulfonsäure, an eine basische Gruppe, wie z.B. Amino, Alkylamino, Dialkylamino, Piperidino, Morpholino oder Pyridino, Salze bilden. Diese Salze enthalten dann die konjugierte Base der Säure als Anion. Geeignete Substituenten, die in deprotonierter Form, wie z.B. The compounds of general formula (I) may be prepared by addition of a suitable inorganic or organic acid such as, for example, mineral acids such as HCl, HBr, H 2 SO 4, H 3 PO 4 or HNO 3, or organic acids, e.g. B. Carboxylic acids, such as formic acid, acetic acid, propionic acid, oxalic acid, lactic acid or salicylic acid or sulfonic acids, such as p-toluenesulfonic acid, to a basic group, such as amino, alkylamino, dialkylamino, piperidino, morpholino or pyridino, salts. These salts then contain the conjugate base of the acid as an anion. Suitable substituents which are in deprotonated form, such as
Sulfonsäuren oder Carbonsäuren, vorliegen, können innere Salze mit ihrerseits protonierbaren Gruppen, wie Aminogruppen bilden. Sulfonic acids or carboxylic acids, may form internal salts with their turn protonatable groups, such as amino groups.
Im Folgenden werden die erfindungsgemäß verwendeten Verbindungen der Formel (I) und ihre Salze "Verbindungen der allgemeinen Formel (I)" bezeichnet. The compounds of the formula (I) used according to the invention and their salts are referred to below as "compounds of the general formula (I)".
Bevorzugt ist die erfindungsgemäße Verwendung von Verbindungen der allgemeinen Formel (I), worin [X-Y] für die Gruppierungen Preference is given to the use according to the invention of compounds of the general formula (I) in which [X-Y] is the grouping
[x-YF [χ-γρ Und [x-Y]3 steht, [x-YF [χ-γρ U nd [x Y] 3 is
Q für die Gruppierungen Q-1 bis Q-6 Q for the groupings Q-1 to Q-6
Q-1 Q-2 Q-3  Q-1 Q-2 Q-3
Q-4 Q-5 und Q-6 sieht, wobei R13, R14, R 5, R16, R17, R18, R19, R20, R23, R24, R25, R26, R28, R29, R30, R31 , R32, R34, R35 und R36 sowie A1 bis A9 jeweils die Bedeutung gemäß der nachstehenden Definitionen haben und wobei der Pfeil für eine Bindung zur jeweiligen Gruppierung C-R6 in der allgemeinen Formel (I) steht, Q-4 Q -5 and Q-6 wherein R 13 , R 14 , R 5 , R 16 , R 17 , R 18 , R 19 , R 20 , R 23 , R 24 , R 25 , R 26 , R 28 , R 29 , R 30 , R 31 , R 32 , R 34 , R 35 and R 36, and A 1 to A 9 are each as defined below and wherein the arrow represents a bond to the respective group CR 6 in the general formula (I),
R1 für (Ci-Ce)-Alkyl, (C3-C8)-Cycloalkyl, (C4-C8)-Cycloalkenyl, (C2-C8)-Alkenyl, (C2-C8)-Alkinyl, (C2-C8)-Alkenyl-(CrC8)-alkyl, (C2-C8)-Alkinyl-(Ci-C8)-alkyl, R 1 is (C 1 -C 6 ) -alkyl, (C 3 -C 8 ) -cycloalkyl, (C 4 -C 8 ) -cycloalkenyl, (C 2 -C 8 ) -alkenyl, (C 2 -C 8 ) -alkynyl , (C 2 -C 8) alkenyl (-C 8) alkyl, (C 2 -C 8) alkynyl (Ci-C 8) alkyl,
(Ci-C8)-Alkoxy-(CrC8)-alkyl. Hydroxy-(d-C8)-alkyl, (Ci-C8)-Haloalkyl, (C2-C8)- Haloalkenyl, (C2-C8)-Haloalkinyl, (Ci-C8)-Haloalkoxy-(Ci-C8)-alkyl, (Ci-C8)- Alkoxy-(Ci-C8)-haloalkyl, (Ci-C8)-Haloalkoxy-(Ci-C8)-haloalkyl, (Ci-C8)-(C 1 -C 8 ) -alkoxy- (C 1 -C 8 ) -alkyl. Hydroxy (dC 8) alkyl, (Ci-C 8) haloalkyl, (C 2 -C 8) - haloalkenyl, (C 2 -C 8) haloalkynyl, (Ci-C8) haloalkoxy (Ci- C 8) alkyl, (Ci-C8) - alkoxy (Ci-C 8) haloalkyl, (Ci-C8) haloalkoxy (Ci-C 8) haloalkyl, (Ci-C 8) -
Alkylthio-(Ci-C8)-alkyl, (Ci-C8)-Haloalkylthio-(CrC8)-alkyl, Aryl, Heteroaryl, Heterocyclyl steht, Alkylthio (C 1 -C 8 ) -alkyl, (C 1 -C 8 ) -haloalkylthio (C 1 -C 8 ) -alkyl, aryl, heteroaryl, heterocyclyl,
R2, R3 und R4 unabhängig voneinander für Wasserstoff, Halogen, (d-C8)-Alkyl, R 2 , R 3 and R 4 independently of one another represent hydrogen, halogen, (C 1 -C 8 ) -alkyl,
(C3-C8)-Cycloalkyl, (C4-C8)-Cycloalkenyl, (C2-C8)-Alkenyl, (C2-C8)-Alkinyl,(C 3 -C 8 ) -cycloalkyl, (C 4 -C 8 ) -cycloalkenyl, (C 2 -C 8 ) -alkenyl, (C 2 -C 8 ) -alkynyl,
(C2-C8)-Alkenyl-(d-C8)-alkyl, (C2-C8)-Alkinyl-(Ci-C8)-alkyl, (Ci-Cs)-Alkoxy- (Ci-Cs)-alkyl, Hydroxy-(Ci-C8)-alkyl, (Ci-Cs)-Haloalkyl, (C2-C8)-Haloalkenyl, (C2-C8)-Haloalkinyl, (Ci-C8)-Haloalkoxy-(Ci-C8)-alkyl, (Ci-C8)-Alkoxy-(Ci-C8)- haloalkyl, (Ci-C8)-Haloalkoxy-(Ci-C8)-haloalkyl, (Ci-C8)-Alkylthio-(Ci-C8)-alkyl, (Ci-C8)-Haloalkylthio-(Ci-C8)-alkyl, Aryl, Heteroaryl, Heterocyclyl stehen, (C 2 -C 8) alkenyl (dC 8) alkyl, (C 2 -C 8) alkynyl (Ci-C 8) alkyl, (Ci-Cs) alkoxy (Ci-Cs) - alkyl, hydroxy (Ci-C 8) alkyl, (Ci-Cs) -haloalkyl, (C 2 -C 8) -haloalkenyl, (C 2 -C 8) haloalkynyl, (Ci-C8) haloalkoxy (C 1 -C 8 ) -alkyl, (C 1 -C 8 ) -alkoxy- (C 1 -C 8 ) -haloalkyl, (C 1 -C 8 ) -haloalkoxy- (C 1 -C 8 ) -haloalkyl, (C 1 -C 8 ) -Alkylthio (C 1 -C 8 ) -alkyl, (C 1 -C 8 ) -haloalkylthio (C 1 -C 8 ) -alkyl, aryl, heteroaryl, heterocyclyl,
R5 für Hydroxy, (Ci-C8)-Alkoxy, Aryloxy, (C3-C8)-Cycloalkyloxy, (C2-C8)-Alkenyloxy, (C2-C8)-Alkenyl-(d-C8)-alkyloxy, (CrC8)-Alkoxy-(Ci-C8)-alkyloxy, (d-C8)- Alkylcarbonyloxy, Arylcarbonyloxy, Heteroarylcarbonyloxy, (Ca-Cs)- Cycloalkylcarbonyloxy, (d-C8)-Alkoxycarbonyloxy, (C2-Cs)-R 5 is hydroxy, (Ci-C 8) alkoxy, aryloxy, (C3-C8) cycloalkyloxy, (C 2 -C 8) alkenyloxy, (C 2 -C 8) alkenyl (dC 8) - alkyloxy, (C 1 -C 8 ) alkoxy- (C 1 -C 8 ) -alkyloxy, (C 1 -C 8 ) -alkylcarbonyloxy, arylcarbonyloxy, heteroarylcarbonyloxy, (Ca-Cs) -cycloalkylcarbonyloxy, (C 1 -C 8) -alkoxycarbonyloxy, (C 2 -Cs ) -
Alkenyloxycarbonyloxy, Aryloxy-(d-C8)-alkyloxy, Aryl-(Ci-C8)-alkyloxy, (d-Cs)- Alkoxy-(Ci-C8)-alkoxy-(Ci-C8)-alkyloxy, (Ci-C8)-Alkylthio-(Ci-C8)-alkyloxy, Tris[(Ci-C8)-alkyl]silyloxy, (Ci-C8)-Alkyl-Bis[(Ci-C8)-alkyl]silyloxy, (Ci-Ce)-Alkyl- bis(Aryl)silyloxy, Aryl-bis[(Ci-C8)— alkyljsilyloxy, Cycloalkyl-bis[(Ci-C8)- alkyljsilyloxy, Halo-bis[(Ci-C8)-alkyl]silyloxy, Tris[(Ci-Ce)-alkyl]silyl-(Ci-Ce)- alkoxy-(Ci-C8)-alkyloxy, steht, Alkenyloxycarbonyloxy, aryloxy- (d-C8) -alkyloxy, aryl- (Ci-C8) -alkyloxy, (d-Cs) -alkoxy- (Ci-C 8 ) -alkoxy- (Ci-C 8 ) -alkyloxy, (Ci -C 8) alkylthio (Ci-C 8 silyloxy) alkyloxy, tris [(Ci-C8) alkyl], (Ci-C8) alkyl-bis [(Ci-C 8) alkyl] silyloxy, (Ci-Ce) -alkyl bis (aryl) silyloxy, aryl-bis [(Ci-C8) - alkyljsilyloxy, cycloalkyl-bis [(Ci-C8) - alkyljsilyloxy, halo-bis [(Ci-C 8 ) alkyl silyloxy, tris [(Ci-Ce) alkyl] silyl (Ci-Ce) - alkoxy (Ci-C8) -alkyloxy, stands,
R6 für Nitro, Amino, Hydroxy, Hydrothio, Thiocyanato, Isothiocyanato, Halogen,R 6 for nitro, amino, hydroxy, hydrothio, thiocyanato, isothiocyanato, halogen,
(Ci-C8)-Alkyl, (C3-C8)-Cycloalkyl, (C2-C8)-Alkenyl, (C4-C8)-Cycloalkenyl, (C2-C8)- Alkinyl, Aryl-(C2-C8)-alkinyl, Tris[(Ci-C8)-alkyl]silyl-(C2-C8)-alkinyl, Aryl, Aryl- (Ci-C8)-alkyl, Aryl-(d-C8)-alkoxy, Heteroaryl, (Ci-C8)-Haloalkyl, (C3-C8)- Halocycloalkyl, (C2-C8)-Haloalkenyl, (Ci-Cs)-Alkoxy, (Ci-Cs)-Haloalkoxy, Aryloxy, Heteroaryloxy, (C3-C8)-Cycloalkyloxy, (C3-C8)-Cycloalkyl-(d-C8)- aikoxy, (C2-C8)- (C2-C8)-Alkenyloxy, (C2-C8)-Alkinyl-(C2-C8)-alkyloxy, Hydroxy- (Ci-Cs)-alkyl, (Ci-C8)-Alkoxy-(Ci-C8)-alkyl, Aryloxy-(Ci-C8)-alkyl, Heteroaryioxy- (Ci-Cs)-alkyl, (d-C8)-Alkylthio, (d-C8)-Haloalkylthio, (d-C8)-Alkoxycarbonyl- (Ci-Cs)-alkylthio, Arylthio, (C3-C8)-Cycloalkylthio, Heteroarylthio, (Ci-C8)- Alkylthio-(Ci-C8)-alkyl, (Ci-Ce)-Alkylamino, Bis[(Ci-C8)-alkyl]amino, (C2-C8)- Alkenylamino, (C3-C8)-Cycloalkylamino, (Ci-Cs)-Alkylcarbonylamino, (C3-C8)- Cycloalkylcarbonylamino, Arylcarbonylamino, Heteroarylcarbonylamino, Formylamino, (Ci-C8)-Haloalkylcarbonylamino, (Ci-C8)-Alkoxycarbonylamino, (Ci-Cs)-Alkylaminocarbonylamino, (Ci-C8)-Alkyl[(d-C8)- Alkyljaminocarbonylamino, (CrC8)-Alkylsulfonylamino, (C3-C8)- Cycloalkylsulfonylamino, Arylsulfonylamino, Hetarylsulfonylamino, Sulfonyl- (Ci-C8)-haloalkylamino, Amino-(Ci-C8)-alkylsulfonyl, Amino-(Ci-C8)- haloalkylsulfonyl, (CrC8)-Alkylaminosulfonyl, Bis[(Ci-C8)-alkyl]aminosulfonyl, (C3-C8)-Cycloalkylaminosulfonyl, (Ci-C8)-Haloalkylaminosulfonyl, (C 1 -C 8 ) -alkyl, (C 3 -C 8 ) -cycloalkyl, (C 2 -C 8 ) -alkenyl, (C 4 -C 8 ) -cycloalkenyl, (C 2 -C 8 ) - Alkynyl, aryl- (C 2 -C 8 ) -alkynyl, tris [(C 1 -C 8 ) -alkyl] silyl- (C 2 -C 8 ) -alkynyl, aryl, aryl- (C 1 -C 8 ) -alkyl, aryl- ( dC 8) alkoxy, heteroaryl, (Ci-C8) -haloalkyl, (C 3 -C 8) - halocycloalkyl, (C2-C8) -haloalkenyl, (Ci-Cs) alkoxy, (Ci-Cs) - haloalkoxy, aryloxy, heteroaryloxy, (C3-C8) cycloalkyloxy, (C3-C8) -cycloalkyl- (dC 8) - alkoxy, (C 2 -C 8) - (C 2 -C 8) alkenyloxy, ( C 2 -C 8) alkynyl (C 2 -C 8) -alkyloxy, hydroxy- (Ci-Cs) alkyl, (Ci-C 8) alkoxy (Ci-C 8) alkyl, aryloxy ( Ci-C 8) alkyl, Heteroaryioxy- (Ci-Cs) alkyl, (dC 8) alkylthio, (dC 8) haloalkylthio, (dC 8) alkoxycarbonyl (Ci-Cs) alkylthio, arylthio, ( C 3 -C 8) cycloalkylthio, heteroarylthio, (Ci-C 8) - alkylthio (Ci-C8) alkyl, (Ci-Ce) alkylamino, bis [(Ci-C 8) alkyl] amino, (C 2 -C 8) - alkenylamino, (C3-C8) cycloalkylamino, (Ci-Cs) alkylcarbonylamino, (C3-C8) - cycloalkylcarbonylamino, arylcarbonylamino, heteroarylcarbonylamino, formylamino, (Ci-C 8) -Haloalkylcarbonylamino , (Ci-C 8 ) alkoxycarbonylamino, (Ci-Cs) -A lkylaminocarbonylamino, (Ci-C 8) alkyl [(dC 8) - Alkyljaminocarbonylamino, (CrC 8) alkylsulfonylamino, (C3-C8) - cycloalkylsulfonylamino, arylsulfonylamino, Hetarylsulfonylamino, sulfonyl (Ci-C 8) -haloalkylamino, amino - (Ci-C8) alkylsulfonyl, amino (Ci-C 8) - haloalkylsulfonyl, (CrC 8) alkylaminosulfonyl, bis [(Ci-C 8) alkyl] aminosulfonyl, (C3-C8) -Cycloalkylaminosulfonyl, (C 1 -C 8 ) -haloalkylaminosulfonyl,
Heteroarylaminosulfonyl, Arylaminosulfonyl, Aryl-(Ci-C8)-alkylaminosulfonyl, (Ci-Cs)-Alkylsulfonyl, (C3-C8)-Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C8)- Alkylsulfinyl, (C3-C8)-Cycloalkylsulfinyl, Arylsulfinyl, N,S-Bis[(d-C8)- alkyljsulfonimidoyl, S-(Ci-C8)-Alkylsulfonimidoyl, (Ci-C8)- Alkylsulfonylaminocarbonyl, (C3-C8)-Cycloalkylsulfonylaminocarbonyl, Aryl- (Ci-Cs)-alkylcarbonylamino, (C3-C8)-Cycloalkyl-(Ci-C8)-alkylcarbonylamino, Heteroarylcarbonylamino, (CrC8)-Alkoxy-(Ci-C8)-alkylcarbonylamino, Hydroxy- (Ci-C8)-alkylcarbonylamino, (Ci-C8)-Alkoxycarbonylamino-(CrC8)- alkylcarbonylamino, Cyano, Cyano-(Ci-C8)-alkyl, Hydroxycarbonyl, (Ci-C8)- Alkoxycarbonyl, (C3-C8)-Cycloalkoxycarbonyl, (C3-C8)-Cycloalkyl-(Ci-C8)- alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C8)-alkoxycarbonyl, (C2-C8)- Alkenyloxycarbonyl, (C2-C8)-Alkinyloxycarbonyl, (CrC8)-Haloalkyloxycarbonyl, (Ci-C8)-Alkoxy-(Ci-C8)-alkoxycarbonyl, (C2-C8)-Alkenyloxy-(Ci-C8)- alkoxycarbonyl, (Ci-C8)-Alkylamino-(CrC8)-alkoxycarbonyl, Tris[(Ci-C8)- alkyl]silyloxy-(d-C8)-alkoxycarbonyl, Bis[(Ci-C8)-Alkyl]amino-(CrC8)- alkoxycarbonyl, (Ci-C8)-Alkyl[(Ci-C8)-alkyl]amino-(Ci-C8)-alkoxycarbonyl, Cyano-(Ci-C8)-alkoxycarbonyl, Heterocyclyl-N-(Ci-C8)-alkoxycarbonyl, Heteroarylaminosulfonyl, arylaminosulfonyl, aryl (Ci-C8) -alkylaminosulfonyl, (Ci-Cs) alkylsulfonyl, (C 3 -C 8) cycloalkylsulfonyl, arylsulfonyl, (Ci-C 8) - alkylsulfinyl, (C 3 -C 8 ) cycloalkylsulfinyl, arylsulfinyl, N, S-bis [(dC 8) - alkyljsulfonimidoyl, S- (Ci-C8) -Alkylsulfonimidoyl, (Ci-C 8) - alkylsulfonylaminocarbonyl, (C 3 -C 8) -Cycloalkylsulfonylaminocarbonyl, aryl (C 1 -C 8 ) -alkylcarbonylamino, (C 3 -C 8 ) -cycloalkyl- (C 1 -C 8 ) -alkylcarbonylamino, heteroarylcarbonylamino, (C 1 -C 8 ) -alkoxy- (C 1 -C 8 ) -alkylcarbonylamino, hydroxy- (C 1 -C 4) -alkylcarbonylamino, C 8 ) -alkylcarbonylamino, (C 1 -C 8 ) -alkoxycarbonylamino- (C 1 -C 8 ) -alkylcarbonylamino, cyano, cyano- (C 1 -C 8 ) -alkyl, hydroxycarbonyl, (C 1 -C 8 ) -alkoxycarbonyl, (C 3 -C 8) -cycloalkoxycarbonyl, (C3-C8) -cycloalkyl- (Ci-C8) - alkoxycarbonyl, aryloxycarbonyl, aryl (Ci-C8) -alkoxycarbonyl, (C2-C8) - alkenyloxycarbonyl, (C2-C8 ) -alkynyloxycarbonyl, (CrC 8) -Haloalkyloxycarbonyl, (Ci-C 8) alkoxy (Ci-C8) -alkoxycarbonyl, (C 2 -C 8) alkenyloxy (Ci-C 8) - a lkoxycarbonyl, (Ci-C 8) alkylamino (-C 8) -alkoxycarbonyl, tris [(Ci-C 8) - alkyl] silyloxy (dC 8) -alkoxycarbonyl, bis [(Ci-C 8) alkyl] amino (CrC 8 ) alkoxycarbonyl, (C 1 -C 8 ) -alkyl [(C 1 -C 8 ) -alkyl] amino- (C 1 -C 8 ) -alkoxycarbonyl, Cyano- (C 1 -C 8) -alkoxycarbonyl, heterocyclyl-N- (C 1 -C 8) -alkoxycarbonyl,
Heteroaryloxycarbonyl, Heteroaryl-(d-C8)-alkoxycarbonyl, Heterocyclyl-(CrC8)- alkoxycarbonyl, Heterocyclyloxycarbonyl, (C2-C8)-Alkenyl-(Ci-C8)- alkoxycarbonyl, (C2-C8)-Alkinyl-(CrC8)-alkoxycarbonyl, Aryl-(C2-C8)- alkinyloxycarbonyl, Aryl-(C2-C8)-alkenyloxycarbonyl, Aminocarbonyl, (Ci-Cs)- Alkylaminocarbonyl, Bis[(Ci-C8)-alkyl]aminocarbonyl, (Ci-C8)-Alkyl[(Ci-C8)- Alkyljaminocarbonyl, (CrC8)-Alkyl[(Ci-C8)-Alkoxy]aminocarbonyl, (C2-C-8)- Alkenylaminocarbonyl, (Ca-CeJ-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C8)-alkylaminocarbonyl, Heteroaryl-(Ci-C8)-alkylaminocarbonyl, Cyano- (Ci-C8)-alkylaminocarbonyl, (Ci-C8)-Haloalkylaminocarbonyl, (C2-C8)-Alkinyl- (CrC8)-alkylaminocarbonyl , (CrC8)-Alkoxycarbonylaminocarbonyl, Aryl-(Ci-Cs)- alkoxycarbonylaminocarbonyl, Hydroxycarbonyl-(Ci-C8)-alkyl, (Ci-Cs)- Alkoxycarbonyl-(Ci-C8)-alkyl, (C3-C8)-Cycloalkoxycarbonyl-(CrC8)-alkyl, (C3-C8)-Cycloalkyl-(Ci-C8)-alkoxycarbonyl-(Ci-C8)-alkyl, (C2-C8)- Alkenyloxycarbonyl-(Ci-C8)-alkyl, Aryl-(Ci-Cs)-alkoxycarbonyl-(Ci-C8)-alkyl, (Ci-C8)-Alkylaminocarbonyl-(CrC8)-alkyl, Aminocarbonyl-(Ci-C8)-alkyl, Heteroaryloxycarbonyl, heteroaryl- (C 1 -C 8) -alkoxycarbonyl, heterocyclyl- (C 1 -C 8) -alkoxycarbonyl, heterocyclyloxycarbonyl, (C 2 -C 8) -alkenyl- (C 1 -C 8) -alkoxycarbonyl, (C 2 -C 8) -alkynyl- (C 1 -C 8) - alkoxycarbonyl, aryl- (C 2 -C 8 ) -alkynyloxycarbonyl, aryl- (C 2 -C 8 ) -alkenyloxycarbonyl, aminocarbonyl, (C 1 -C 8 ) -alkylaminocarbonyl, bis [(C 1 -C 8) -alkyl] -aminocarbonyl, (C 1 -C 8) Alkyl [(C 1 -C 8)] alkylaminocarbonyl, (C 1 -C 8) -alkyl [(C 1 -C 8) -alkoxy] aminocarbonyl, (C 2 -C 8) -alkenylaminocarbonyl, (C 2 -C 6 -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (Ci -C 8) -alkylaminocarbonyl, heteroaryl- (C 1 -C 8) -alkylaminocarbonyl, cyano- (C 1 -C 8) -alkylaminocarbonyl, (C 1 -C 8) -haloalkylaminocarbonyl, (C 2 -C 8) -alkynyl- (C 1 -C 8) -alkylaminocarbonyl, (CrC 8 ) Alkoxycarbonylaminocarbonyl, aryl- (Ci-Cs) -alkoxycarbonylaminocarbonyl, hydroxycarbonyl- (Ci-C8) -alkyl, (Ci-Cs) - alkoxycarbonyl- (Ci-C8) -alkyl, (C3-C8) -cycloalkoxycarbonyl- (CrC8 ) alkyl, (C3-C8) -cycloalkyl- (Ci-C8) alkoxycarbonyl (Ci-C 8) alkyl, (C 2 -C 8) - alkenyloxycarbonyl (Ci-C8) alkyl, A ryl- (C 1 -C 5) -alkoxycarbonyl- (C 1 -C 8) -alkyl, (C 1 -C 8) -alkylaminocarbonyl- (C 1 -C 8) -alkyl, aminocarbonyl- (C 1 -C 8) -alkyl,
Bis[(Ci-C8)-alkyl]aminocarbonyl-(Ci-C8)-alkyl, (C3-C8)-Cycloalkylaminocarbonyl- (Ci-Cs)-alkyL Aryl-(Ci-C8)-a!kylaminocarbonyl-(Ci-C8)-alkyl, Heteroaryl-(Ci-C8)- alkylaminocarbonyl-(Ci-C8)-alkyl, Cyano-(Ci-C8)-alkylaminocarbonyl-(Ci-C8)- aikyl, (Ci-C8)-Haloalkylaminocarbonyl-(Ci-C8)-alkyl, (C2-C8)-Alkinyl-(Ci-C8)- alkylaminocarbonyl-(Ci-C8)-alkyl, (C3-C8)-Cycloalkyl-(Ci-C8)- alkylaminocarbonyl-(Ci-C8)-alkyl, (Ci-C8)-Alkoxycarbonylaminocarbonyl- (Ci-C8)-alkyl, Aryl-(Ci-C8)-alkoxycarbonylaminocarbonyl-(Ci-C8)-alkyl, (CrC8)- Alkoxycarbonyl-(Ci-C8)-alkylaminocarbonyl, Hydroxycarbonyl-(Ci-Cs)- alkylaminocarbonyl, Aryl-(Ci-C8)-alkoxycarbonyl-(Ci-C8)-alkylaminocarbonyl, Aminocarbonyl-(Ci-C8)-alkylaminocarbonyl, (Ci-C8)-Alkylaminocarbonyl- (Ci-Cs)-alkylaminocarbonyl, Bis [(Ci-C8) -alkyl] aminocarbonyl- (Ci-C8) -alkyl, (C3-C8) -cycloalkylaminocarbonyl- (Ci-Cs) -alkyL aryl- (Ci-C8) -alkylaminocarbonyl- C 8 ) -alkyl, heteroaryl- (C 1 -C 8 ) -alkylaminocarbonyl- (C 1 -C 8 ) -alkyl, cyano- (C 1 -C 8 ) -alkylaminocarbonyl- (C 1 -C 8 ) -acyl, (C 1 -C 8 ) - Haloalkylaminocarbonyl- (Ci-C8) alkyl, (C 2 -C 8) alkynyl (Ci-C8) - alkylaminocarbonyl (Ci-C8) alkyl, (C3-C8) -cycloalkyl- (Ci-C 8 ) -alkylaminocarbonyl- (C 1 -C 8 ) -alkyl, (C 1 -C 8 ) -alkoxycarbonylaminocarbonyl- (C 1 -C 8 ) -alkyl, aryl- (C 1 -C 8 ) -alkoxycarbonylaminocarbonyl- (C 1 -C 8 ) - alkyl, (CrC 8 ) - alkoxycarbonyl- (C 1 -C 8 ) -alkylaminocarbonyl, hydroxycarbonyl- (C 1 -C 8 ) -alkylaminocarbonyl, aryl- (C 1 -C 8 ) -alkoxycarbonyl- (C 1 -C 8 ) -alkylaminocarbonyl, aminocarbonyl- (C 1 -C 8 ) -alkylaminocarbonyl, (C 1 -C 8 ) -alkylaminocarbonyl- (C 1 -C 8 ) -alkylaminocarbonyl,
(C3-C8)-Cycloalkylaminocarbonyl-(Ci-C8)-alkylaminocarbonyl, (C3-Cs)- Cycloalkyl-(Ci-C8)-alkylaminocarbonyl, (C3-C8)-Cyc!oalkyl-(Ci-C8)- alkylaminocarbonyl-(Ci-C8)-alkyl, (C3-C8)-Cycloalkyl-(Ci-C8)- alkylaminocarbonyl-(Ci-C8)-alkylaminocarbonyl, (C2-C8)-Alkenyl-(Ci-C8)- alkylaminocarbonyl, (C2-C8)-Alkenylam!nocarbonyl-(Ci-C8)-alkyl, (C2-C8)- Alkenyl-(Ci-C8)-alkylaminocarbonyi-(Ci-C8)-alkyl, (Ci-C8)-Alkylcarbonyl, (C3-C8)- Cycloalkylcarbonyl, Arylcarbonyl, Formyl, Hydroxyiminomethyl, Aminoiminomethyl, (Ci-C8)-Alkoxyiminomethyl, (Ci-C8)-Alkylaminoiminomethyl, Bis[(Ci-C8)-alkyl]aminoiminomethyl, (C3-C8)-Cycloalkoxyiminomethyl, (Ca-Ce)- Cycloaikyl-(Ci-C8)-alkoximinomethyl, Aryloximinomethyl, Aryl-(d-C8)- alkoxyiminomethyl, Aryl-(Ci-C8)-alkylaminoiminomethyl, (C2-C-8)- Alkenyloxyiminomethyl, Arylaminoiminomethyl, Arylsulfonylaminoiminomethyl, Heteroaryl-(Ci-C8)-alkyl, Heterocycly!-(Ci-C8)-alkyl, (C3-C8) -Cycloalkylaminocarbonyl- (Ci-C8) -alkylaminocarbonyl, (C3-Cs) - cycloalkyl- (Ci-C8) -alkylaminocarbonyl, (C3-C8) -Cyc oalkyl- (Ci-C 8)! - alkylaminocarbonyl (Ci-C8) alkyl, (C 3 -C 8) -cycloalkyl- (Ci-C8) - alkylaminocarbonyl (Ci-C8) alkylaminocarbonyl, (C2-C8) alkenyl ( Ci-C 8) - alkylaminocarbonyl, (C2-C8) -Alkenylam nocarbonyl- (Ci-C8) alkyl, (C2-C8) - alkenyl (C 8) -alkylaminocarbonyi- (C 8 ) -alkyl, (C 1 -C 8 ) -alkylcarbonyl, (C 3 -C 8 ) -cycloalkylcarbonyl, arylcarbonyl, formyl, hydroxyiminomethyl, Aminoiminomethyl, (C 1 -C 8) -alkoxyiminomethyl, (C 1 -C 8) -alkylaminoiminomethyl, bis [(C 1 -C 8) -alkyl] aminoiminomethyl, (C 3 -C 8) -cycloalkoxyiminomethyl, (Ca-Ce) -cycloalkyl- (C 1 -C 8 ) -alkoximinomethyl, aryloximinomethyl, aryl- (C 1 -C 8) -alkoxyiminomethyl, aryl- (C 1 -C 8) -alkylaminoiminomethyl, (C 2 -C 8) -alkenyloxyiminomethyl, arylaminoiminomethyl, arylsulfonylaminoiminomethyl, heteroaryl- (C 1 -C 8 ) -alkyl , Heterocyclic! (C 1 -C 8 ) -alkyl,
Hydroxycarbonylheterocyclyl, (CrC8)-Alkoxycarbonylheterocyclyl, (C2-C8)- Aikenyloxycarbonylheterocyclyl, (C2-C8)-Alkenyl-(Ci-C8)- alkoxycarbonylheterocyclyl, Aryl-(Ci-Cs)-alkoxycarbonylheierocyclyl, (C3-C-8)- Cycloalkoxycarbonylheterocyclyl, (C3-Cs)-Cycloalkyl-(Ci-C8)- alkoxycarbonylheterocyclyl, Aminocarbonylheterocyclyl, (Ci-C8)- Alkylaminocarbonylheterocyclyl, Bis[(Ci-C8)-Alkyl]aminocarbonylheterocyclyl, (C3-C8)-Cycloalkylaminocarbonylheierocyclyl, Aryl-(Ci-Cs)- alkylaminocarbonylheterocyclyl, (C2-C8)-Alkenylaminocarbonylheterocyclyl, Hydroxycarbonylheterocyclyl-(Ci-C8)-alkyl, (Ci-Cs)-Alkoxycarbonylheterocyclyl- (Ci-Cs)-alkyl, Hydroxycarbonyl-(C3-C8)-cycloalkyl-(Ci-C8)-alkyl, (Ci-C8)- Alkoxycarbony!-(C3-C8)-cycloalkyl-(Ci-C8)-alkyl, Hydroxyaminocarbonyl, (Ci-Cs)-Alkoxyaminocarbonyl, Aryl-(Ci-Cs)-alkoxyaminocarbonyl, Heterocyclyl, (Ci-Ce)-Alkylcarbonyloxy, Arylcarbonyloxy, Heteroarylcarbonyloxy, (C3-C8)- Cycloalkylcarbonyloxy, (Ci-C8)-Alkoxycarbonyloxy, (C2-Cs)- Alkenyloxycarbonyloxy, Aminosulfonyl, (Ci-C8)-Alkoxycarbonyl-heterocyclyl-N- carbonyl, (CrC8)-Alkoxycarbonyl-(Ci-C8)-a!kyl-heterocyclylidenaminocarbonyl, (Ci-C8)-Alkoxycarbonylheierocyclyliden-(Ci-C8)-alkylaminocarbonyl (d-Cs)- Alkoxycarbonyl-(Ci-C8)-Alkyl((Ci-C8)-alkyl)aminocarbonyli (d-Cs)- Alkoxycarbonyl-(C3-C8)-cycloalkylidenaminocarbonyl, Heterocyclyl-N-carbonyl, (Ci-C8)-Alkoxy-(Ci-C8)-alkylaminocarbonyl steht, Hydroxycarbonylheterocyclyl, (C 1 -C 8) -alkoxycarbonylheterocyclyl, (C 2 -C 8 ) -aikynyloxycarbonylheterocyclyl, (C 2 -C 8 ) -alkenyl- (C 1 -C 8 ) -alkoxycarbonyl-heterocyclyl, aryl- (C 1 -C 8 ) -alkoxycarbonylheierocyclyl, (C 3 -C-8) - Cycloalkoxycarbonylheterocyclyl, (C3-Cs) cycloalkyl (Ci-C8) - alkoxycarbonylheterocyclyl, Aminocarbonylheterocyclyl, (Ci-C 8) - Alkylaminocarbonylheterocyclyl, bis [(Ci-C 8) -alkyl] aminocarbonylheterocyclyl, (C3-C8) -Cycloalkylaminocarbonylheierocyclyl, aryl- (C 1 -C 8 ) -alkylaminocarbonylheterocyclyl, (C 2 -C 8 ) -alkenylaminocarbonylheterocyclyl, hydroxycarbonylheterocyclyl- (C 1 -C 8 ) -alkyl, (C 1 -C 5) -alkoxycarbonylheterocyclyl- (C 1 -C 8) -alkyl, hydroxycarbonyl- (C 3 -C 8 ) -cycloalkyl- (C 1 -C 8 ) -alkyl, (C 1 -C 8 ) -alkoxycarbony! (C 3 -C 8 ) -cycloalkyl- (C 1 -C 8 ) -alkyl, hydroxyaminocarbonyl, Cs) alkoxyaminocarbonyl, aryl (Ci-Cs) alkoxyaminocarbonyl, heterocyclyl, (Ci-Ce) alkylcarbonyloxy, arylcarbonyloxy, heteroarylcarbonyloxy, (C3-C8) - cycloalkylcarbonyloxy, (Ci-C8) -alkoxycarbonyloxy, (C2-Cs ) - Alkenyloxycarbonyloxy, aminosulfonyl, (Ci-C8) alkoxycarbonyl-heterocyclyl-N-carbonyl, (CrC 8 ) alkoxycarbonyl- (Ci-C8) -alkyl-heterocyclylidenaminocarbonyl, (Ci-C8) -alkoxycarbonylheierocyclyliden- (Ci-C 8 ) -alkylaminocarbonyl (C 1 -C 5 ) -alkoxycarbonyl- (C 1 -C 8 ) -alkyl (C 1 -C 8 ) -alkyl) aminocarbonyl- i (C 1 -C 5) -alkoxycarbonyl- (C 3 -C 8 ) -cycloalkylideneaminocarbonyl, heterocyclyl- N-carbonyl, (C 1 -C 8 ) -alkoxy- (C 1 -C 8 ) -alkylaminocarbonyl,
R7, R8, R9, R10, R11 und R12 unabhängig voneinander für Wasserstoff, (Ci-Cs)-Alkyl, (C3-Cs)-Cycloalkyl, (C2-C8)-A!kenyl, (C2-C8)-Alkenyl-(Ci-C8)-a!kyl, (Ci-Cs)- Alkoxy-(Ci-C8)-alkyl, Hydroxy-(Ci-C8)-alkyl, (CrC8)-Haloalkyl, (C2-C8)- Haloalkenyl, (Ci-C8)-Haloalkoxy-(Ci-C8)-alkyl, (Ci-C8)-Alkoxy-(Ci-C8)-haloalkyi, (Ci-C8)-Haloalkoxy-(Ci-C8)-haloalkyl, (Ci-Cs)-Alkoxy, (Ci-Cs)-Alkylthio, (Ci-C8)- Alkylamino, Halogen, Amino stehen, wobei mindestens eine der Gruppen R7, R8, R9, R10, R1 1 und R12 nicht für Wasserstoff steht und R3 und R4 mit dem Atom, an das sie gebunden sind, eine exo-Alkylidengruppe oder einen vollständig gesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 6-gliedrigen Ring bilden, R 7 , R 8 , R 9 , R 10 , R 11 and R 12 independently of one another are hydrogen, (C 1 -C 5 ) -alkyl, (C 3 -C 8 ) -cycloalkyl, (C 2 -C 8 ) -alkenyl , (C 2 -C 8 ) -alkenyl- (C 1 -C 8 ) -alkyl, (C 1 -C 8 ) -alkoxy- (C 1 -C 8 ) -alkyl, hydroxy- (C 1 -C 8 ) -alkyl, (CrC 8 ) -haloalkyl, (C 2 -C 8 ) - haloalkenyl, (Ci-C 8 ) -haloalkoxy- (Ci-C 8 ) -alkyl, (Ci-C 8 ) -alkoxy- (Ci-C 8 ) -haloalkyi , (Ci-C8) haloalkoxy (Ci-C 8) haloalkyl, (Ci-Cs) alkoxy, (Ci-Cs) -alkylthio, (Ci-C8) - alkylamino, halogen, amino stand, wherein at least one of the groups R 7, R 8, R 9, R 10, R 1 1 and R 12 is not hydrogen, and R 3 and R 4 with the atom to which they are attached, an exo-alkylidene group or a fully saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 3 to 6 form a -ligmoid ring,
R1 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 1 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
R1 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, R 1 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
R3 und R7 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 3 and R 7 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
R3 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, R 3 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
R1 und R3 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 1 and R 3 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
R7 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 7 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally by O (oxygen), S (sulfur) or form a group NH, NR 37 interrupted and optionally further substituted 5 to 7-membered ring,
R3 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, R 3 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
R7 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, R 7 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
R13, R14, R15 und R16 unabhängig voneinander für Wasserstoff, Halogen, Nitro, Amino, Cyano, (Ci-Cs)-Alkyl, Aryl, Heteroaryl, (C3-C8)-Cycloalkyl, (C4-C8)-Cycloalkenyl, (C -C8)-Alkenyl, (C2-C8)-Alkinyl, (C2-C8)-Alkenyl-(Ci-C8)-alkyl, (C2-C8)-Alkinyl- (d-C8)-alkyl, Hydroxy, (d-C8)-Alkoxy, (Ci-C8)-Alkoxy-(Ci-C8)-alkoxy, (d-C8)- Alkoxy-(Ci-C8)-alkyl, Hydroxy-(Ci-C8)-alkyl, (Ci-Cs)-Haloalkoxy, (Ci-C8)- Haloalkyl, (C2-C8)-Haloalkenyl, (C2-C8)-Haloalkinyl, (Ci-C8)-Haloalkoxy-(Ci-C8)- alkyl, (Ci-C8)-Alkoxy-(Ci-C8)-haloalkyl, (Ci-C8)-Haloalkoxy-(Ci-C8)-haloalkyl, Hydrothio, (d-C8)-Alkylthio, (d-C8)-Haloalkylthio, (Ci-C8)-Alkylthio-(Ci-C8)- alkyl, (Ci-C8)-Haloalkylthio-(Ci-C8)-alkyl, (d-C8)-Alkylamino, Bis-[(Ci-C8)- alkyljamino, (C2-C8)-Alkenylamino, (C3-C8)-Cycloalkylamino, (d-C8)- Alkylcarbonylamino, (C3-C8)-Cycloalkylcarbonylamino, Arylcarbonylamino, Heteroarylcarbonylamino, Formylamino, (Ci-C8)-Haloalkylcarbonylamino, R 13 , R 14 , R 15 and R 16 independently of one another represent hydrogen, halogen, nitro, amino, cyano, (C 1 -C 5 ) -alkyl, aryl, heteroaryl, (C 3 -C 8 ) -cycloalkyl, (C 4 - C 8 ) -cycloalkenyl, (C 8 -C 8 ) -alkenyl, (C 2 -C 8 ) -alkynyl, (C 2 -C 8 ) -alkenyl- (C 1 -C 8 ) -alkyl, (C 2 -C 8 ) alkynyl (dC 8) alkyl, hydroxy, (dC 8) alkoxy, (Ci-C 8) alkoxy (Ci-C 8) alkoxy, (dC 8) - alkoxy (Ci-C 8 ) alkyl, hydroxy (Ci-C 8) alkyl, (Ci-Cs) haloalkoxy, (Ci-C 8) - haloalkyl, (C 2 -C 8) -haloalkenyl, (C 2 -C 8) - haloalkynyl, (Ci-C8) haloalkoxy (Ci-C 8) - alkyl, (Ci-C 8) alkoxy (Ci-C 8) haloalkyl, (Ci-C8) haloalkoxy (Ci- C 8) haloalkyl, Hydrothio, (dC 8) alkylthio, (dC 8) haloalkylthio, (Ci-C8) alkylthio (Ci-C8) - alkyl, (Ci-C 8) -Haloalkylthio- ( Ci-C 8) alkyl, (dC 8) alkylamino, - bis [(Ci-C 8) - alkyljamino, (C 2 -C 8) -alkenylamino, (C3-C8) cycloalkylamino, (dC 8) Alkylcarbonylamino, (C 3 -C 8 ) -cycloalkylcarbonylamino, arylcarbonylamino, heteroarylcarbonylamino, formylamino, (C 1 -C 8 ) -haloalkylc carbonylamino,
(Ci-Cs)-Alkoxycarbonylamino, (Ci-C8)-Alkylaminocarbonylamino, (d-C8)- Alkyl[(Ci-C8)-Alkyl]aminocarbonylamino, (Ci-Cs)-Alkylsulfonylamino, (C3-C8)- Cycloalkylsulfonylamino, Arylsulfonylamino, Hetarylsulfonylamino, Sulfonyl- (Ci-Cs)-haloalkylamino, Amino-(Ci-Ce)-alkylsulfonyl, Amino-(Ci-C8)- haloalkylsulfonyl, (CrCeJ-Alkylaminosulfonyl, Bis[(CrC8)-alkyl]aminosulfonyl, (Ca-Ce Cycloalkylaminosulfonyl, (CrC8)-Haloalkylaminosulfonyl, (Ci-Cs) alkoxycarbonylamino, (Ci-C8) alkylaminocarbonylamino, (DC 8) - alkyl [(Ci-C 8) alkyl] aminocarbonylamino, (Ci-Cs) alkylsulfonylamino, (C3-C8) - Cycloalkylsulfonylamino, arylsulfonylamino, hetarylsulfonylamino, sulfonyl- (Ci-Cs) -haloalkylamino, amino- (Ci-Ce) -alkylsulfonyl, amino- (Ci-C8) -haloalkylsulfonyl, (CrCeJ-alkylaminosulfonyl, bis [(CrC8) -alkyl] aminosulfonyl , (C 1 -C 6 -cycloalkylaminosulfonyl, (C 1 -C 8) -haloalkylaminosulfonyl,
Heteroarylaminosulfonyl, Arylaminosulfonyl, Aryl-(Ci-C8)-alkylaminosulfonyl, (d-C8)-Alkylsulfonyl, (C3-C8)-Cycloalkylsulfonyl, Arylsulfonyl, Hydroxycarbonyl, (d-C8)-Alkoxycarbonyl, (Cs-CsJ-Cycloalkoxycarbonyl, (C3-C8)-Cycloalkyl- (Ci-C8)-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C8)-alkoxycarbonyl, (C2-G3)- Alkenyloxycarbonyl, (C2-C8)-Alkinyloxycarbonyl, Aminocarbonyl, (Ci-C8)- Alkylaminocarbonyl, Bis[(CrC8)-alkyl]aminocarbonyl, (Ci-C8)-Alkyl[(Ci-C8)- Alkyljaminocarbonyl, (Ci-C8)-Alkyl[(CrC8)-Alkoxy]aminocarbonyl, (C2-C8)- Alkenylaminocarbonyl, (C3-C8)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C8)-alkylaminocarbonyl stehen, Heteroarylaminosulfonyl, arylaminosulfonyl, aryl- (C 1 -C 8) -alkylaminosulfonyl, (C 1 -C 8) -alkylsulfonyl, (C 3 -C 8) -cycloalkylsulfonyl, arylsulfonyl, hydroxycarbonyl, (C 1 -C 8) -alkoxycarbonyl, (Cs-CsJ-cycloalkoxycarbonyl, ( C3-C8) cycloalkyl (C 1 -C 8) -alkoxycarbonyl, aryloxycarbonyl, aryl- (C 1 -C 8 ) -alkoxycarbonyl, (C 2 -G 3) -alkenyloxycarbonyl, (C 2 -C 8 ) -alkynyloxycarbonyl, aminocarbonyl, (C 1 -C 8 ) -alkylaminocarbonyl, bis [( -C 8) alkyl] aminocarbonyl, (Ci-C 8) alkyl [(Ci-C 8) - Alkyljaminocarbonyl, (Ci-C8) alkyl, [(CRC8) alkoxy] aminocarbonyl, (C2-C8) - alkenylaminocarbonyl , (C 3 -C 8 ) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 8 ) -alkylaminocarbonyl,
A1, A2, A3 und A4 gleich oder verschieden sind und unabhängig voneinander für N A 1 , A 2 , A 3 and A 4 are the same or different and are independently N
(Stickstoff) oder die Gruppierungen C-H, C-CH3, C-F, C-Cl, C-Br, C-l, C-OCF3, C-OCH3, C-CF3, C-CO2H, C-CO2CH3 stehen, wobei jedoch in keinem Fall mehr als zwei N-Atome benachbart sind, (Nitrogen) or the groupings CH, C-CH 3, CF, C-Cl, C-Br, CI, C-OCF3, C-OCH3, C-CF3, C-CO2H, C-CO2CH3 are, however, in no more than two N-atoms are adjacent,
R17 und R18 unabhängig voneinander für Wasserstoff, Halogen, (Ci-Cs)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (C3-C8)-Cycloalkyl, (C2-C8)-Alkenyl, (C2-C8)-Alkinyl, (Ci-C8)-Alkoxy, (Ci-C8)-Alkoxy-(Ci-C8)-alkyl, Aryloxy-(Ci-C8)-alkyl, (d-Ce)- Haloalkoxy, (CrC8)-Haloalkyl, (Ci-C8)-Haloalkoxy-(Ci-C8)-alkyl, (d-C8)-Alkoxy- (Ci-C8)-haloalkyl, (Ci-C8)-Haloalkoxy-(Ci-C8)-haloalkyl, (Ci-C8)-Alkylthio, (Ci-C8)-Haloalkylthio, (Ci-C8)-Alkylthio-(Ci-C8)-alkyl, Hydroxycarbonyl, (Ci-Ce)- Alkoxycarbonyl, (C3-C8)-Cycloalkoxycarbonyl, (C3-C8)-Cycloalkyl-(Ci-C8)- alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C8)-alkoxycarbonyl, (C2-G3)- Alkenyloxycarbonyl, (C2-C8)-Alkinyloxycarbonyl, Aminocarbonyl, (CrC8)- Alkylaminocarbonyl, Bis[(CrC8)-alkyl]aminocarbonyl, (Ci-C8)-Alkyl[(Ci-C8)- Alkyljaminocarbonyl, (Ci-C8)-Alkyl[(CrC8)-Alkoxy]aminocarbonyl, (C2-C8)- Alkenylaminocarbonyl, (C3-C8)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(CrC8)-alkylaminocarbonyl stehen, R 17 and R 18 independently of one another represent hydrogen, halogen, (C 1 -C 5 ) -alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 8 ) -cycloalkyl, (C 2 -C 8 ) -alkenyl, (C 2 - C 8 ) -alkynyl, (C 1 -C 8 ) -alkoxy, (C 1 -C 8 ) -alkoxy- (C 1 -C 8 ) -alkyl, aryloxy- (C 1 -C 8 ) -alkyl, (d-Ce) - Haloalkoxy, (C 1 -C 8 ) -haloalkyl, (C 1 -C 8 ) -haloalkoxy- (C 1 -C 8 ) -alkyl, (C 1 -C 8 ) -alkoxy- (C 1 -C 8 ) -haloalkyl, (C 1 -C 8 ) - Haloalkoxy- (C 1 -C 8 ) -haloalkyl, (C 1 -C 8 ) -alkylthio, (C 1 -C 8 ) -haloalkylthio, (C 1 -C 8 ) -alkylthio (C 1 -C 8 ) -alkyl, hydroxycarbonyl, ( C 1 -C 6) - alkoxycarbonyl, (C 3 -C 8 ) -cycloalkoxycarbonyl, (C 3 -C 8 ) -cycloalkyl- (C 1 -C 8 ) -alkoxycarbonyl, aryloxycarbonyl, aryl- (C 1 -C 8 ) -alkoxycarbonyl, (C 2 -G 3) Alkenyloxycarbonyl, (C 2 -C 8 ) -alkynyloxycarbonyl, aminocarbonyl, (C 1 -C 8) -alkylaminocarbonyl, bis [(C 1 -C 8) -alkyl] aminocarbonyl, (C 1 -C 8) -alkyl [(C 1 -C 8) -alkyl] aminocarbonyl, (C 1 -C 8 ) -Alkyl [(C 1 -C 8) -alkoxy] -aminocarbonyl, (C 2 -C 8) -alkenylaminocarbonyl, (C 3 -C 8) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 8) -alkylaminocarbonyl n,
A5 für S (Schwefel), O (Sauerstoff) oder die Gruppierungen N-H, N-CH3, N-CH2CH3, N- CH(CH3)2, N-C02t-Bu, N-Aryl, N-Heteroaryl, N-Heterocyclyl steht, A 5 represents S (sulfur), O (oxygen) or the groupings NH, N-CH 3 , N-CH 2 CH 3 , N-CH (CH 3 ) 2 , N-CO 2 t-Bu, N-aryl, N-heteroaryl, N-heterocyclyl is
R19, R20, R23 und R24 unabhängig voneinander für Wasserstoff, (Ci-Ce)-Alkyl, Halogen, (C3-C8)-Cycloalkyl, Aryl, Heteroaryl, Heterocyclyl, (C2-C8)-Alkenyl, (C2-C8)- Alkenyl-(CrC8)-alkyl, Aryl-(CrC8)-alkyl, (d-C8)-Alkoxy, (Ci-C8)-Alkoxy-(Ci-C8)- alkoxy, (Ci-C8)-Alkoxy-(CrC8)-alkyl. Hydroxy, (d-C8)-Haloalkyl, (d-C8)- Haloalkylthio stehen, R19 und R23 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 19 , R 20 , R 23 and R 24 independently of one another represent hydrogen, (C 1 -C 6 ) -alkyl, halogen, (C 3 -C 8 ) -cycloalkyl, aryl, heteroaryl, heterocyclyl, (C 2 -C 8 ) - alkenyl, (C 2 -C 8) - alkenyl (-C 8) alkyl, aryl (-C 8) alkyl, (dC 8) alkoxy, (Ci-C 8) alkoxy (Ci-C 8) - alkoxy, (C 1 -C 8 ) -alkoxy- (C 1 -C 8 ) -alkyl. Hydroxy, (dC 8 ) -haloalkyl, (dC 8 ) -haloalkylthio, R 19 and R 23 with the atoms to which they are attached form a completely saturated or partially saturated, optionally further substituted 5 to 7-membered ring,
A6, A7 gleich oder verschieden sind und unabhängig voneinander für O (Sauerstoff), S (Schwefel), N-H, N-OCH3, N-CH3 oder die Gruppierung CR21 R22 stehen, wobei jedoch in keinem Fall zwei N-, O- oder S-Atome benachbart sind, und wobei R21 und R22 in der Gruppierung CR21 R22 jeweils gleiche oder verschiedene A 6 , A 7 are the same or different and are each independently O (oxygen), S (sulfur), NH, N-OCH 3 , N-CH 3 or the group CR 21 R 22 , but in no case two N -, O or S atoms are adjacent, and wherein R 21 and R 22 in the group CR 21 R 22 are identical or different
Bedeutungen gemäß der nachstehenden Definition haben und  Have meanings as defined below and
R21 und R22 unabhängig voneinander für Wasserstoff, Halogen, (d-Cs)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (C3-C8)-Cycloalkyl, (C2-C8)-Alkenyl, (d-C8)-Alkoxy, (Ci-C8)-Alkoxy-(Ci-C8)-alkyl, Aryloxy-(Ci-C8)-alkyl, (Ci-C8)-Haloalkoxy, (Ci-C8)- Haloalkyl, (Ci-C8)-Haloalkoxy-(Ci-C8)-alkyl, (Ci-C8)-Alkoxy-(CrC8)-haloalkyl, (CrC8)-Haloalkoxy-(Ci-C8)-haloalkyl, (d-C8)-Alkylthio, (d-C8)-Haloalkylthio, (Ci-C8)-Alkylthio-(Ci-C8)-alkyl, Hydroxycarbonyl, (d-C8)-Alkoxycarbonyl, R 21 and R 22 independently represent hydrogen, halogen, (C 1 -C 5) -alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 8 ) -cycloalkyl, (C 2 -C 8 ) -alkenyl, (C 1 -C 8 ) -alkoxy , (C 1 -C 8 ) -alkoxy- (C 1 -C 8 ) -alkyl, aryloxy- (C 1 -C 8 ) -alkyl, (C 1 -C 8 ) -haloalkoxy, (C 1 -C 8 ) -haloalkyl, (Ci -C 8) haloalkoxy (Ci-C 8) alkyl, (Ci-C 8) alkoxy (CrC 8) -haloalkyl, (CrC 8) haloalkoxy (Ci-C 8) haloalkyl, (dC 8 ) -alkylthio, (C 1 -C 8 ) -haloalkylthio, (C 1 -C 8 ) -alkylthio (C 1 -C 8 ) -alkyl, hydroxycarbonyl, (C 1 -C 8 ) -alkoxycarbonyl,
(C3-C8)-Cycloalkoxycarbonyl, (C3-C8)-Cycloalkyl-(Ci-C8)-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C8)-alkoxycarbonyl, (C2-C8)-Alkenyloxycarbonyl, (C2-Cs)-Alkinyloxycarbonyl, Aminocarbonyl, (Ci-C8)-Alkylaminocarbonyl, Bis[(CrC8)-alkyl]aminocarbonyl, (Ci-C8)-Alkyl[(CrC8)-Alkyl]aminocarbonyl, (Ci-C8)-Alkyl[(Ci-C8)-Alkoxy]aminocarbonyl, (C2-C8)-Alkenylaminocarbonyl, (C3-C8)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-Cs)- alkylaminocarbonyl, Amino, (d-C8)-Alkylamino, (C3-C8)-Cycloalkylamino, Bis- [(Ci-C8)-Alkyl]amino stehen, (C 3 -C 8 ) -cycloalkoxycarbonyl, (C 3 -C 8 ) -cycloalkyl- (C 1 -C 8 ) -alkoxycarbonyl, aryloxycarbonyl, aryl- (C 1 -C 8 ) -alkoxycarbonyl, (C 2 -C 8 ) -alkenyloxycarbonyl, (C2 -Cs) -alkynyloxycarbonyl, aminocarbonyl, (C 1 -C 8) -alkylaminocarbonyl, bis [(C 1 -C 8) -alkyl] aminocarbonyl, (C 1 -C 8) -alkyl [(C 1 -C 8) -alkyl] aminocarbonyl, (C 1 -C 8) -alkyl [ (C 1 -C 8 ) -alkoxy] -aminocarbonyl, (C 2 -C 8 ) -alkenylaminocarbonyl, (C 3 -C 8 ) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 8 ) -alkylaminocarbonyl, amino, (C 1 -C 8 ) -alkylamino , (C 3 -C 8 ) -cycloalkylamino, bis- [(C 1 -C 8 ) -alkyl] -amino,
R25, R26, R28 und R29 unabhängig voneinander für Wasserstoff, (Ci-Cs)-Alkyl, Halogen, (C3-C8)-Cycloalkyl, Aryl, Heteroaryl, Heterocyclyl, (C2-C8)-Alkenyl, Aryl-(Ci-Ce)- alkyl, (Ci-C8)-Alkoxy, (Ci-C8)-Alkoxy-(Ci-C8)-alkoxy, (Ci-C8)-Alkoxy-(Ci-C8)- alkyl, (d-C8)-Haloalkyl stehen, R 25, R 26, R 28 and R 29 are independently hydrogen, (Ci-Cs) alkyl, halogen, (C3-C8) cycloalkyl, aryl, heteroaryl, heterocyclyl, (C 2 -C 8) alkenyl , Aryl- (C 1 -C 6 ) -alkyl, (C 1 -C 8 ) -alkoxy, (C 1 -C 8 ) -alkoxy- (C 1 -C 8 ) -alkoxy, (C 1 -C 8 ) -alkoxy- (C 1 -C 4) -alkoxy C 8 ) -alkyl, (dC 8 ) -haloalkyl,
A8 für O (Sauerstoff), S (Schwefel), N-H, N-CH3, N-OCH3 oder die Gruppierung CHR27 steht und wobei R27 in der Gruppierung CHR27 die Bedeutung gemäß der nachstehenden Definition hat, R27 für Wasserstoff, Halogen, (Ci-CeJ-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (Ca-Ce)- Cycloalkyl, (C2-C8)-Alkenyl, (CrC8)-Alkoxy, (Ci-C8)-Alkoxy-(Ci-C8)-alkyl, Aryloxy-(CrC8)-alkyl, (d-C8)-Haloalkoxy, (d-C8)-Haloalkyl, (Ci-Cs)-Alkoxy- (d-C8)-haloalkyl, (Ci-C8)-Haloalkoxy-(CrC8)-haloalkyl, (d-C8)-Alkylthio, A 8 is O (oxygen), S (sulfur), NH, N-CH 3 , N -OCH 3 or the moiety CHR 27 , and wherein R 27 in the moiety CHR 27 has the meaning as defined below, R 27 is hydrogen, halogen, (Ci-CeJ-alkyl, aryl, heteroaryl, heterocyclyl, (Ca-Ce) - cycloalkyl, (C 2 -C 8) alkenyl, (CrC 8) -alkoxy, (Ci-C 8 ) alkoxy (Ci-C 8) alkyl, aryloxy- (CrC 8) alkyl, (dC 8) -haloalkoxy, (dC 8) -haloalkyl, (Ci-Cs) alkoxy (dC 8) -haloalkyl , (C 1 -C 8 ) -haloalkoxy- (C 1 -C 8 ) -haloalkyl, (C 1 -C 8 ) -alkylthio,
(Ci-Cs)-Haloalkylthio, (Ci-C8)-Alkylthio-(Ci-C8)-alkyl, Hydroxycarbonyl, (d-C8)- Alkoxycarbonyl, (C3-C8)-Cycloalkoxycarbonyl, Aryl-(d-C8)-alkoxycarbonyl, (C2-C8)-Alkenyloxycarbonyl, (C2-C8)-Alkinyloxycarbonyl, Aminocarbonyl, (C 1 -C 5) -haloalkylthio, (C 1 -C 8 ) -alkylthio (C 1 -C 8 ) -alkyl, hydroxycarbonyl, (C 1 -C 8 ) -alkoxycarbonyl, (C 3 -C 8 ) -cycloalkoxycarbonyl, aryl- (C 1 -C 8 ) alkoxycarbonyl, (C 2 -C 8 ) -alkenyloxycarbonyl, (C 2 -C 8 ) -alkynyloxycarbonyl, aminocarbonyl,
(Ci-Cs)-Alkylaminocarbonyl, Bis[(Ci-C8)-alkyl]aminocarbonyl, (Ci-C8)- Alkyl[(Ci-C8)-Alkyl]aminocarbonyl, (Ci-C8)-Alkyl[(Ci-C8)-Alkoxy]aminocarbonyl,(Ci-Cs) alkylaminocarbonyl, bis [(Ci-C 8) alkyl] aminocarbonyl, (Ci-C 8) - alkyl [(Ci-C 8) alkyl] aminocarbonyl, (Ci-C 8) alkyl [ (C 1 -C 8 ) -alkoxy] aminocarbonyl,
(C2-C8)-Alkenylaminocarbonyl, (C3-C8)-Cycloalkylaminocarbonyl, (C 2 -C 8 ) -alkenylaminocarbonyl, (C 3 -C 8 ) -cycloalkylaminocarbonyl,
Arylaminocarbonyl, Aryl-(Ci-C8)-alkylaminocarbonyl, Amino, (Ci-Cs)-Alkylamino, (C3-C8)-Cycloalkylamino, Bis-[(Ci-C8)-Alkyl]amino steht, R30, R3 , R32, R34, R35 und R36 unabhängig voneinander für Wasserstoff, (Ci-C8)-Alkyl, Halogen, (C:rC8)-Cycloalkyl, Aryl, Heteroaryl, Heterocyclyl, (C2-C8)-Alkenyl, (d-C8)-Alkoxy, (Ci-C8)-Alkoxy-(d-C8)-alkoxy, (Ci-C8)-Alkoxy-(CrC8)-alkyl, (Ci-Cs)-Haloalkyl, (Ci-C8)-Alkylthio, (Ci-Cs)-Haloalkylthio stehen, A9 für O (Sauerstoff), S (Schwefel), N-H, N-CH3, N-OCH3 oder die Gruppierung CHR steht und wobei R33 in der Gruppierung CHR33 die Bedeutung gemäß der nachstehenden Definition hat und Arylaminocarbonyl, aryl- (C 1 -C 8 ) -alkylaminocarbonyl, amino, (C 1 -C 8 ) -alkylamino, (C 3 -C 8 ) -cycloalkylamino, bis- [(C 1 -C 8 ) -alkyl] -amino, R 30 , R 3 , R 32 , R 34 , R 35 and R 36 independently of one another represent hydrogen, (C 1 -C 8 ) -alkyl, halogen, (C: rC 8 ) -cycloalkyl, aryl, heteroaryl, heterocyclyl, (C 2 -C 8 ) alkenyl, (dC 8) alkoxy, (Ci-C 8) alkoxy (dC 8) alkoxy, (Ci-C 8) alkoxy (CrC 8) alkyl, (Ci-Cs) -haloalkyl , (C 1 -C 8 ) -alkylthio, (C 1 -C 8 ) -haloalkylthio, A 9 is O (oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the grouping CHR and where R 33 in the grouping CHR 33 has the meaning as defined below and
R33 für Wasserstoff, Halogen, (d-C8)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (Ca-C8)- Cycloalkyl. (C2-C8)-Alkenyl, (d-C8)-Alkoxy, (Ci-C8)-Alkoxy-(CrC8)-alkyl,R 33 is hydrogen, halogen, (DC 8) alkyl, aryl, heteroaryl, heterocyclyl, (Ca-C8) - cycloalkyl. (C 2 -C 8) alkenyl, (DC 8) alkoxy, (Ci-C 8) alkoxy (CrC 8) alkyl,
Aryloxy-(Ci-C8)-alkyl, (Ci-C8)-Haloalkoxy, (d-C8)-Haloalkyl, (d-C8)-Alkylthio, (Ci-Cs)-Haloalkylthio, Hydroxycarbonyl, (Ci-Ce)-Alkoxycarbonyl, (Ca-Ce)- Cycloalkoxycarbonyl, Aryl-(Ci-C8)-alkoxycarbonyl, (C2-C8)-Alkenyloxycarbonyl, (C2-C8)-Alkinyloxycarbonyl, Aminocarbonyl, (Ci-C8)-Alkylaminocarbonyl, Bis[(Ci-C8)-alkyl]aminocarbonyl, (Ci-C8)-Alkyl[(Ci-C8)-Alkyl]aminocarbonyl,Aryloxy (Ci-C8) alkyl, (Ci-C8) -haloalkoxy, (DC 8) -haloalkyl, (DC 8) alkylthio, (Ci-Cs) haloalkylthio, hydroxycarbonyl, (Ci-Ce) - Alkoxycarbonyl, (Ca-Ce) -cycloalkoxycarbonyl, aryl- (C 1 -C 8) -alkoxycarbonyl, (C 2 -C 8) -alkenyloxycarbonyl, (C 2 -C 8) -alkynyloxycarbonyl, aminocarbonyl, (C 1 -C 8) -alkylaminocarbonyl, bis [(Ci -C 8) alkyl] aminocarbonyl, (Ci-C 8) alkyl [(Ci-C 8) -alkyl] aminocarbonyl,
(Ci-C8)-Alkyl[(Ci-C8)-Alkoxy]aminocarbonyl, (C2-C8)-Alkenylaminocarbonyl, (C3-C8)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C8)- alkylaminocarbonyl, Amino, (CrC8)-Alkylamino, (C3-C8)-Cycloalkylamino, Bis- [(Ci-C8)-Alkyl]amino steht, R37 für (CrC8)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (C3-C8)-Cycloalkyl, (C2-C8)-Alkenyl, (Ci-C8)-Alkoxy, (d-C8)-Alkoxy-(Ci-C8)-alkyl, Aryloxy-(Ci-C8)-alkyl, (Ci-C8)- Alkoxycarbonyl, (C3-C8)- Cycloalkoxycarbonyl, Aryl-(CrC8)-alkoxycarbonyl, (C2-C8)-Alkenyloxycarbonyl, (C2-C8)-Alkinyloxycarbonyl, (Ci-C8)-Alkylcarbonyl,(C 1 -C 8 ) -alkyl [(C 1 -C 8 ) -alkoxy] -aminocarbonyl, (C 2 -C 8 ) -alkenylaminocarbonyl, (C 3 -C 8 ) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 8 ) -alkylaminocarbonyl, Amino, (C 1 -C 8 ) -alkylamino, (C 3 -C 8 ) -cycloalkylamino, bis- [(C 1 -C 8 ) -alkyl] -amino, R 37 is (CrC 8) alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 8) cycloalkyl, (C 2 -C 8) alkenyl, (Ci-C 8) alkoxy, (DC 8) - alkoxy (Ci-C 8) alkyl, aryloxy (Ci-C8) alkyl, (Ci-C8) - alkoxycarbonyl, (C3-C8) - cycloalkoxycarbonyl, aryl (-C 8) -alkoxycarbonyl, ( C 2 -C 8 ) -alkenyloxycarbonyl, (C 2 -C 8 ) -alkynyloxycarbonyl, (C 1 -C 8 ) -alkylcarbonyl,
(C3-C8)-Cycloalkylcarbonyl, Arylcarbonyl, Heteroarylcarbonyl steht. (C3-C8) cycloalkylcarbonyl, arylcarbonyl, heteroarylcarbonyl stands.
Besonders bevorzugt ist die erfindungsgemäße Verwendung von Verbindungen der allgemeinen Formel (I), worin Particularly preferred is the use according to the invention of compounds of general formula (I) wherein
[X-Y] für die Gruppierungen [X-Y] for the groupings
[x-Y]i u nd [χ-γρ steht, Q für die Gruppierungen Q-1 bis Q-6 [xY] i and [χ-γρ s , Q stands for the groupings Q-1 to Q-6
steht, wobei R13, R14, R15, R16, R17, R18, R19, R20, R23, R24, R25, R26, R28, R29, R30, R31, R32, R34, R35 und R36 sowie A1 bis A9 jeweils die Bedeutung gemäß der nachstehenden Definitionen haben und wobei der Pfeil für eine Bindung zur jeweiligen Gruppierung C-R6 in der allgemeinen Formel (I) steht, R1 für (Ci-C7)-Alkyl, (C3-C7)-Cycloalkyl, (C4-C7)-Cycloalkenyl, (C2-C7)-Alkenyl, (C2-C7)-Alkinyl, (C2-C7)-Alkenyl-(Ci-C7)-aikyl, (C2-C7)-Alkinyl-(Ci-C7)-alkyi, (Ci-C7)-Alkoxy-(Ci-C7)-alkyl, Hydroxy-(Ci-C7)-alkyl, (Ci-C7)-Haloalkyl, (C2-C7)- Haloalkenyl, (C2-C7)-Haloalkinyl, (Ci-C7)-Haloalkoxy-(d-C7)-alkyl, (C1-C7)- Alkoxy-(d-C7)-haloalkyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-haloalkyi, (C1-C7)- Alkylthio-(d-C7)-alkyL (Ci-C7)-Haloalkylthio-(Ci-C7)-alkyl steht, where R 13 , R 14 , R 15 , R 16 , R 17 , R 18 , R 19 , R 20 , R 23 , R 24 , R 25 , R 26 , R 28 , R 29 , R 30 , R 31 , R 32 , R 34 , R 35 and R 36, and A 1 to A 9 are each as defined below and wherein the arrow represents a bond to the respective group CR 6 in the general formula (I), R 1 is (C 1 -C 7 ) -alkyl, (C 3 -C 7 ) -cycloalkyl, (C 4 -C 7 ) -cycloalkenyl, (C 2 -C 7 ) -alkenyl, (C 2 -C 7 ) - alkynyl, (C 2 -C 7) (alkenyl (Ci-C7) -alkyl, (C 2 -C 7) alkynyl (C 7) -alkyi, (Ci-C7) alkoxy Ci-C 7) alkyl, hydroxy (Ci-C7) alkyl, (Ci-C7) haloalkyl, (C2-C7) - haloalkenyl, (C 2 -C 7) haloalkynyl, (Ci-C 7) haloalkoxy (dC 7) alkyl, (C1-C7) - alkoxy (dC 7) -haloalkyl, (Ci-C7) haloalkoxy (Ci-C 7) -haloalkyi, (C1-C7) - alkylthio (dC 7) alkyl (Ci-C 7) -Haloalkylthio- (Ci-C7) alkyl,
R2, R3 und R4 unabhängig voneinander für Wasserstoff, Halogen, (Ci-C7)-Alkyl, R 2 , R 3 and R 4 independently of one another represent hydrogen, halogen, (C 1 -C 7 ) -alkyl,
(C3-C7)-Cycloalkyl, (C4-C7)-Cycloalkenyl, (C2-C7)-Alkenyl, (C2-C7)-Alkinyl, (C2-C7)-Alkenyl-(Ci-C7)-alkyl, (C2-C7)-Alkinyl-(Ci-C7)-alkyl, (Ci-C7)-Alkoxy- (CrC7)-alkyl, Hydroxy-(d-C7)-alkyi, (Ci-C7)-Haloalkyl, (C2-C7)-Haioalkenyl, (C2-C7)-Haioalkinyl, (Ci-C7)-Haloalkoxy-(CrC7)-alkyl, (Ci-C7)-Alkoxy-(Ci-C7)- haloalkyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-haloalkyi, (Ci-C7)-Aikylthio-(Ci-C7)-alkyl, (CrC7)-Haloalkylthio-(Ci-C7)-alkyl stehen, (C 3 -C 7 ) -cycloalkyl, (C 4 -C 7 ) -cycloalkenyl, (C 2 -C 7 ) -alkenyl, (C 2 -C 7 ) -alkynyl, (C 2 -C 7 ) -alkenyl- ( Ci-C 7) alkyl, (C 2 -C 7) alkynyl (Ci-C7) alkyl, (Ci-C7) alkoxy (CrC 7) alkyl, hydroxy (dC 7) - alkyi, (Ci-C7) haloalkyl, (C 2 -C 7) -Haioalkenyl, (C 2 -C 7) -Haioalkinyl, (Ci-C7) haloalkoxy (-C 7) alkyl, (Ci- C 7 ) -alkoxy- (C 1 -C 7 ) -haloalkyl, (C 1 -C 7 ) -haloalkoxy- (C 1 -C 7 ) -haloalkyl, (C 1 -C 7 ) -alkylthio (C 1 -C 7 ) -alkyl , (C 1 -C 7 ) -haloalkylthio (C 1 -C 7 ) -alkyl,
R5 für Hydroxy, (d-C7)-Alkoxy, Aryloxy, (C-3-C7)-Cycloalkyloxy, (C2-C7)-Alkenyloxy, (C2-C7)-Alkenyl-(CrC7)-alkyioxy, (CrC7)-Alkoxy-(Ci-C7)-alkyloxy, (C1-C7)- Alkylcarbonyloxy, Arylcarbonyloxy, Heteroarylcarbonyioxy, (C3-C7)- Cycloalkylcarbonyloxy, (Ci-C7)-Alkoxycarbonyloxy, (C2-C7)- Aikenyioxycarbonyloxy, Aryioxy-(Ci-C7)-aikyloxy, Aryl-(Ci-C7)-alkyioxy, (C1-C7)- Alkoxy-(Ci-C7)-alkoxy-(CrC7)-aikyloxy, (Ci-C7)-Alkylthio-(CrC7)-alkyioxy, Tris[(Ci-C7)-alkyl]silyloxy, (Ci-C7)-Alkyl-Bis[(CrC7)-alkyl]siiyloxy, (d-C7)-Alkyl- bis(Aryl)silyloxy, Aryl-bis[(Ci-C7)— alkyljsilyloxy, Cycloalkyl-bis[(Ci-C7)- aikyijsilyloxy, Halo-bis[(Ci-C7)-alkyl]silyloxy, Tris[(Ci-C7)-alkyl]silyl-(Ci-C7)- alkoxy-(d-C7)-alkyloxy, steht, R 5 is hydroxy, (dC 7) alkoxy, aryloxy, (C 3 -C 7) cycloalkyloxy, (C 2 -C 7) alkenyloxy, (C 2 -C 7) alkenyl (CrC 7) - alkyioxy, (CrC 7) alkoxy (Ci-C7) alkyloxy, (C1-C7) - alkylcarbonyloxy, arylcarbonyloxy, Heteroarylcarbonyioxy, (C3-C7) - cycloalkylcarbonyloxy, (Ci-C7) alkoxycarbonyloxy, (C 2 -C 7) - Aikenyioxycarbonyloxy, Aryioxy- (Ci-C 7) -aikyloxy, aryl (Ci-C 7) -alkyioxy, (C1-C7) - alkoxy (Ci-C7) alkoxy (CrC 7) -acyloxy, (Ci-C 7 ) -alkylthio (CrC 7 ) -alkyioxy, tris [(Ci-C 7 ) -alkyl] silyloxy, (Ci-C 7 ) -alkyl-bis [(CrC 7 ) -alkyl] siiyloxy, (dC 7 ) alkyl bis (aryl) silyloxy, aryl bis [(Ci-C 7 ) alkyljsilyloxy, cycloalkyl bis [(Ci-C 7 ) aikyijsilyloxy, halo bis [(Ci-C 7 ) -alkyl] silyloxy, tris [(C 1 -C 7 ) -alkyl] silyl- (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -alkyloxy,
R6 für Nitro, Amino, Hydroxy, Hydrothio, Thiocyanato, Isothiocyanato, Halogen,R 6 for nitro, amino, hydroxy, hydrothio, thiocyanato, isothiocyanato, halogen,
(Ci-C7)-Alkyl, (C3-C7)-Cycloalkyl, (C2-C7)-Alkenyl, (C4-C7)-Cycloalkenyl, (C2-C7)- Alkinyl. Aryl-(C2-C7)-alkinyl, Tris[(Ci-C7)-alkyl]silyl-(C2-C7)-alkinyl, Aryl, Aryl- (d-C7)-alkyl, Aryl-(CrC7)-alkoxy, Heteroaryl, (Ci-C7)-Haloalkyl, (C3-C7)- Halocycloalkyl, (C2-C7)-Haloalkenyl, (Ci-C7)-Alkoxy, (Ci-C7)-Haloalkoxy, Aryloxy, Heteroaryloxy, (C3-C7)-Cycloalkyloxy, (C3-C7)-Cycloalkyl-(Ci-C7)- alkoxy, (C2-C7)- (C2-C7)-Alkenyloxy, (C2-C7)-Alkinyl-(C2-C7)-alkyloxy, Hydroxy- (d-C7)-alkyl, (Ci-C7)-Alkoxy-(Ci-C7)-alkyl, Aryloxy-(d-C7)-alkyl, Heteroaryloxy- (Ci-C7)-alkyl, (Ci-C7)-Alkylthio, (Ci-C7)-Haloalkylthio, (Ci-C7)-Alkoxycarbonyl- (d-C7)-alkylthio, Arylthio, (C3-C7)-Cycloalkylthio, Heteroarylthio, (C1-C7)- Alkylthio-(Ci-C7)-alkyl. (Ci-C7)-Alkylamino, Bis[(Ci-C7)-alkyl]amino, (C2-C7)- Alkenylamino, (C:rC7)-Cycloalkylamino, (Ci-C7)-Alkylcarbonylamino, (C3-C7)- Cycloalkylcarbonylamino, Arylcarbonylamino, Heteroarylcarbonylamino, Formylamino, (Ci-C7)-Haloalkylcarbonylamino, (Ci-C7)-Alkoxycarbonylamino, (Ci-C7)-Alkylaminocarbonylamino, (Ci-C7)-Alkyl[(Ci-C7)- Alkyl]aminocarbonylamino, (Ci-C7)-Alkylsulfonylamino, (C3-C7)- Cycloalkylsulfonylamino, Arylsulfonylamino, Hetarylsulfonylamino, Sulfonyl- (Ci-C7)-haloalkylamino, Amino-(Ci-C7)-alkylsulfonyl, Amino-(Ci-C7)- haloalkylsulfonyl, (CrC7)-Alkylaminosulfonyl, Bis[(Ci-C7)-alkyl]aminosulfonyl, (C3-C7)-CycloalkylaminosulfonyL (CrC7)-Haloalkylaminosulfonyl, (C 1 -C 7 ) -alkyl, (C 3 -C 7 ) -cycloalkyl, (C 2 -C 7 ) -alkenyl, (C 4 -C 7 ) -cycloalkenyl, (C 2 -C 7 ) -alkynyl. Aryl (C 2 -C 7) alkynyl, tris [(Ci-C 7) alkyl] silyl (C 2 -C 7) alkynyl, aryl, aryl (dC 7) alkyl, aryl (-C 7) alkoxy, heteroaryl, (Ci-C7) haloalkyl, (C3-C7) - halocycloalkyl, (C 2 -C 7) haloalkenyl, (Ci-C7) alkoxy, (Ci-C7) - haloalkoxy, aryloxy, heteroaryloxy, (C3-C7) cycloalkyloxy, (C3-C7) -cycloalkyl- (Ci-C7) - alkoxy, (C 2 -C 7) - (C 2 -C 7) alkenyloxy , (C 2 -C 7) alkynyl (C 2 -C 7) alkyloxy, hydroxy (dC 7) alkyl, (Ci-C7) alkoxy (Ci-C7) alkyl, aryloxy (dC 7 ) -alkyl, heteroaryloxy (Ci-C7) alkyl, (Ci-C7) -alkylthio, (Ci-C 7) haloalkylthio, (Ci-C 7) alkoxycarbonyl (dC 7) alkylthio, arylthio, (C 3 -C 7 ) -cycloalkylthio, heteroarylthio, (C 1 -C 7 ) -alkylthio (C 1 -C 7 ) -alkyl. (C 1 -C 7 ) -alkylamino, bis [(C 1 -C 7 ) -alkyl] -amino, (C 2 -C 7 ) -alkenylamino, (C 1 -C -cycloalkylamino, (C 1 -C 7 ) -alkylcarbonylamino, (C 3 -C7) - cycloalkylcarbonylamino, arylcarbonylamino, heteroarylcarbonylamino, formylamino, (C 1 -C 7 ) -haloalkylcarbonylamino, (C 1 -C 7 ) -alkoxycarbonylamino, (C 1 -C 7 ) -alkylaminocarbonylamino, (C 1 -C 7 ) -alkyl [(Ci-C 7 ) alkyl] aminocarbonylamino, (C 1 -C 7 ) -alkylsulfonylamino, (C 3 -C 7 ) -cycloalkylsulfonylamino, arylsulfonylamino, hetarylsulfonylamino, sulfonyl- (C 1 -C 7) -haloalkylamino, amino- (C 1 -C 7) -alkylsulfonyl, amino- ( C 1 -C 7) - haloalkylsulfonyl, (C 1 -C 7) -alkylaminosulfonyl, bis [(C 1 -C 7) -alkyl] aminosulfonyl, (C 3 -C 7) -cycloalkylaminosulfonyL (C 1 -C 7) -haloalkylaminosulfonyl,
Heteroarylaminosulfonyl, Arylaminosulfonyi, Aryl-(Ci-C7)-alkylaminosulfonyl, (Ci-C7)-Alkylsulfonyl, (C3-C7)-Cycloalkylsulfonyl, Arylsulfonyl, (C1-C7)- AlkylsulfinyL (C3-C7)-Cycloalkylsulfinyl, Arylsulfinyl, N,S-Bis[(Ci-C7)- alkyljsulfonimidoyl, S-(CrC7)-Alkylsulfonimidoyl, (C1-C7)- Alkylsulfonylaminocarbonyl, (C3-C7)-Cycloalkylsulfonylaminocarbonyl, Aryl- (Ci-C7)-alkylcarbonylamino, (C3-C7)-Cycloalkyl-(Ci-C7)-alkylcarbonylamino, Heteroarylcarbonylamino, (Ci-C7)-Alkoxy-(Ci-C7)-alkylcarbonylamino, Hydroxy- (Ci-C7)-alkylcarbonylamino, (Ci-C7)-Alkoxycarbonylamino-(Ci-C7)- alkylcarbonylamino, Cyano, Cyano-(Ci-C-7)-alkyl, Hydroxycarbonyl, (C1-C7)- Alkoxycarbonyl, (C3-C7)-Cycloalkoxycarbonyl, (C3-C7)-Cycloalkyl-(Ci-C7)- alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C7)-alkoxycarbonyl, (C2-C7)- Alkenyloxycarbonyl, (C2-C7)-Alkinyloxycarbonyl, (Ci-C7)-Haloalkyloxycarbonyl, (Ci-C7)-Alkoxy-(Ci-C7)-alkoxycarbonyl, (C2-C7)-Alkenyloxy-(Ci-C7)- alkoxycarbonyl, (Ci-C7)-Alkylamino-(Ci-C7)-alkoxycarbonyl, Tris[(d-C7)- alkyl]silyloxy-(Ci-C7)-alkoxycarbonyl, Bis[(Ci-C7)-Alkyl]amino-(Ci-C7)- alkoxycarbonyl, (Ci-C7)-Alkyl[(Ci-C7)-alkyl]amino-(Ci-C7)-alkoxycarbonyl, Cyano-(Ci-C7)-alkoxycarbonyl, Heterocyclyl-N-(Ci-C7)-alkoxycarbonyl, Heteroarylaminosulfonyl, Arylaminosulfonyi, aryl (Ci-C7) alkylaminosulfonyl, (Ci-C7) alkylsulphonyl, (C 3 -C 7) cycloalkylsulfonyl, arylsulfonyl, (C1-C7) - alkylsulfinyl (C 3 -C 7) - Cycloalkylsulfinyl, arylsulfinyl, N, S-bis [(C 1 -C 7 ) -alkylsulfonimidoyl, S- (C 1 -C 7 ) -alkylsulfonimidoyl, (C 1 -C 7) -alkylsulfonylaminocarbonyl, (C 3 -C 7 ) -cycloalkylsulfonylaminocarbonyl, aryl- (C 1 -C 7 ) alkylcarbonylamino, (C 3 -C 7) -cycloalkyl- (C 1 -C 7) -alkylcarbonylamino, heteroarylcarbonylamino, (C 1 -C 7) -alkoxy- (C 1 -C 7) -alkylcarbonylamino, hydroxy- (C 1 -C 7) -alkylcarbonylamino, C7) alkoxycarbonylamino (Ci-C7) - alkylcarbonylamino, cyano, cyano (Ci-C7) alkyl, hydroxycarbonyl, (C1-C7) - alkoxycarbonyl, (C3-C7) -cycloalkoxycarbonyl, (C 3 -C 7 ) -Cycloalkyl- (C 1 -C 7) -alkoxycarbonyl, aryloxycarbonyl, aryl- (C 1 -C 7) -alkoxycarbonyl, (C 2 -C 7) -alkenyloxycarbonyl, (C 2 -C 7) -alkynyloxycarbonyl, (C 1 -C 7) -haloalkyloxycarbonyl, (Ci -C 7) alkoxy (Ci-C7) -alkoxycarbonyl, (C2-C7) alkenyloxy (Ci-C7) - alkoxycarbonyl, (Ci-C7) alkylamino (Ci- C7) -alkoxycarbonyl, tris [(C 1 -C 7) -alkyl] silyloxy- (C 1 -C 7) -alkoxycarbonyl, bis [(C 1 -C 7) -alkyl] amino- (C 1 -C 7) -alkoxycarbonyl, (C 1 -C 7) Alkyl [(C 1 -C 7) -alkyl] amino- (C 1 -C 7) -alkoxycarbonyl, cyano- (C 1 -C 7) -alkoxycarbonyl, heterocyclyl-N- (C 1 -C 7) -alkoxycarbonyl,
Heteroaryloxycarbonyl, Heteroaryl-(Ci-C7)-alkoxycarbonyl, Heterocyclyl-(CrC7)- alkoxycarbonyl, HeterocyclyloxycarbonyL (C2-C7)-Alkenyl-(Ci-C7)- alkoxycarbonyl, (C2-C7)-Alkinyl-(CrC7)-alkoxycarbonyl, Aryl-(C2-C7)- alkinyloxycarbonyl, Aryl-(C2-C7)-alkenyloxycarbonyl, Aminocarbonyl , (C1-C7)- Alkylaminocarbonyl, Bis[(Ci-C7)-alkyl]aminocarbonyl, (Ci-C7)-Alkyl[(Ci-C7)- Alkyl]aminocarbonyl, (Ci-C7)-Alkyl[(Ci-C7)-Alkoxy]aminocarbonyl, (C2-C7)- Alkenylaminocarbonyl, (C;i-C7)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C7)-alkylaminocarbonyl, Heteroaryl-(Ci-C7)-alkylaminocarbonyl, Cyano- (Ci-C7)-alkylaminocarbonyl, (Ci-C7)-Haloalkylaminocarbonyl, (C2-C7)-Alkinyl- (CrC7)-alkylaminocarbonyl, (CrC7)-Alkoxycarbonylaminocarbonyl, Aryl-(d-C7)- alkoxycarbonylaminocarbonyl, Hydroxycarbonyl-(d-C7)-alkyl, (C1-C7)- Alkoxycarbonyl-(d-C7)-alkyl, (C3-C7)-Cycloalkoxycarbonyl-(Ci-C7)-alkyl, (C3-C7)-Cycloalkyl-(Ci-C7)-alkoxycarbonyl-(Ci-C7)-alkyL (C2-C7)- Alkenyloxycarbonyl-(Ci-C7)-alkyl, Aryl-(Ci-C7)-alkoxycarbonyl-(Ci-C7)-alkyl, (Ci-C7)-Alkylaminocarbonyl-(Ci-C7)-alkyl, Aminocarbonyl-(Ci-C7)-alkyl, Heteroaryloxycarbonyl, heteroaryl- (C 1 -C 7) -alkoxycarbonyl, heterocyclyl- (C 1 -C 7) -alkoxycarbonyl, heterocyclyloxycarbonyL (C 2 -C 7) -alkenyl- (C 1 -C 7) -alkoxycarbonyl, (C 2 -C 7) -alkynyl- (C 1 -C 7) -alkoxycarbonyl , Aryl- (C 2 -C 7) -alkynyloxycarbonyl, aryl- (C 2 -C 7) -alkenyloxycarbonyl, aminocarbonyl, (C 1 -C 7) -alkylaminocarbonyl, bis [(C 1 -C 7) -alkyl] aminocarbonyl, (C 1 -C 7) -alkyl [(C-C7) - Alkyl] aminocarbonyl, (C 1 -C 7) -alkyl [(C 1 -C 7) -alkoxy] aminocarbonyl, (C 2 -C 7) -alkenylaminocarbonyl, (C 1 -C 7) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 7) - alkylaminocarbonyl, heteroaryl- (C 1 -C 7) -alkylaminocarbonyl, cyano- (C 1 -C 7) -alkylaminocarbonyl, (C 1 -C 7) -haloalkylaminocarbonyl, (C 2 -C 7) -alkynyl- (C 1 -C 7) -alkylaminocarbonyl, (C 1 -C 7) -alkoxycarbonylaminocarbonyl, Aryl- (C 1 -C 7) -alkoxycarbonylaminocarbonyl, hydroxycarbonyl- (C 1 -C 7) -alkyl, (C 1 -C 7) -alkoxycarbonyl- (C 1 -C 7) -alkyl, (C 3 -C 7) -cycloalkoxycarbonyl- (C 1 -C 7) - alkyl, (C3-C7) -cycloalkyl- (Ci-C7) alkoxycarbonyl (Ci-C7) alkyl (C2-C7) - alkenyloxycarbonyl (Ci-C7) alkyl, aryl (Ci-C7) - alkoxycarbonyl- (C 1 -C 7) -alkyl, (C 1 -C 7) -alkylaminocarbonyl- (C 1 -C 7) -alkyl, aminocarbonyl- (C 1 -C 7) -alkyl,
Bis[(Ci-C7)-alkyl]aminocarbonyl-(CrC7)-alkyl, (C3-C7)-Cycloalkylaminocarbonyl- (Ci-C7)-alkyl, Aryl-(Ci-C7)-alkylaminocarbonyl-(Ci-C7)-alkyL Heteroaryl-(Ci-C7)- alkylaminocarbonyl-(Ci-C7)-alkyl, Cyano-(Ci-C7)-alkylaminocarbonyl-(CrC7)- alkyl, (Ci-C7)-Haloalkylaminocarbonyl-(Ci-C7)-alkyl, (C2-C7)-Alkiny!-(Ci-C7)- alkylaminocarbonyl-(Ci-C7)-alkyl, (C3-C7)-Cycloalkyl-(Ci-C7)- alkylaminocarbonyl-(Ci-C7)-alkyl, (Ci-C7)-Alkoxycarbonylaminocarbonyl- (d-C7)-alkyl, Aryl-(CrC7)-alkoxycarbonylaminocarbonyl-(Ci-C7)-alkyl, (C1-C7)- Alkoxycarbonyl-(Ci-C7)-alkylaminocarbonyl, Hydroxycarbonyl-(Ci-C7)- alkylaminocarbonyl, Aryl-(Ci-C7)-alkoxycarbonyl-(Ci-C7)-alkylaminocarbonyl, Aminocarbonyl-(Ci-C7)-alkylaminocarbonyl, (Ci-C7)-Alkylaminocarbonyl- (Ci-C7)-alkylaminocarbonyl. Bis [(Ci-C7) alkyl] aminocarbonyl (CRC7) alkyl, (C3-C7) -Cycloalkylaminocarbonyl- (Ci-C7) alkyl, aryl (Ci-C7) alkylaminocarbonyl (Ci-C 7 ) -alkyL heteroaryl- (C 1 -C 7 ) -alkylaminocarbonyl- (C 1 -C 7 ) -alkyl, cyano- (C 1 -C 7 ) -alkylaminocarbonyl- (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -haloalkylaminocarbonyl- (C 1 -C 4 -alkyl) 7) alkyl, (C2-C7) -Alkiny - (Ci-C7) - alkylaminocarbonyl (Ci-C7) alkyl, (C 3 -C 7) cycloalkyl (Ci-C7) - alkylaminocarbonyl (C 1 -C 7) -alkyl, (C 1 -C 7) -alkoxycarbonylaminocarbonyl- (C 1 -C 7) -alkyl, aryl- (C 1 -C 7) -alkoxycarbonylaminocarbonyl- (C 1 -C 7) -alkyl, (C 1 -C 7) -alkoxycarbonyl- C 1 -C 7) -alkylaminocarbonyl, hydroxycarbonyl- (C 1 -C 7) -alkylaminocarbonyl, aryl- (C 1 -C 7) -alkoxycarbonyl- (C 1 -C 7) -alkylaminocarbonyl, aminocarbonyl- (C 1 -C 7) -alkylaminocarbonyl, (C 1 -C 7) -Alkylaminocarbonyl- (Ci-C7) -alkylaminocarbonyl.
(C3-C7)-Cycloalkylaminocarbonyl-(Ci-C7)-alkylaminocarbonyl, (C3-C7)- Cycloalkyl-(Ci-C7)-alkylaminocarbonyl, (C3-C7)-Cycloalkyl-(Ci-C7)- alkylaminocarbonyl-(Ci-C7)-alkyl, (C3-C7)-Cycloalkyl-(Ci-C7)- alkylaminocarbonyl-(Ci-C7)-alkylaminocarbonyl, (C2-C7)-Alkenyl-(Ci-C7)- alkylaminocarbonyl, (C2-C7)-Alkenylaminocarbonyl-(Ci-C7)-alkyl, (C2-C7)- Alkenyl-(Ci-C7)-alkylaminocarbonyl-(Ci-C7)-alkyl, (Ci-C7)-AlkylcarbonyL (C3-C7)- Cycloalkylcarbonyl, Arylcarbonyl, Formyl, Hydroxyiminomethyl, (C 3 -C 7 ) -cycloalkylaminocarbonyl- (C 1 -C 7 ) -alkylaminocarbonyl, (C 3 -C 7 ) -cycloalkyl- (C 1 -C 7 ) -alkylaminocarbonyl, (C 3 -C 7 ) -cycloalkyl- (C 1 -C 7 ) -alkylaminocarbonyl (C 1 -C 7 ) -alkyl, (C 3 -C 7 ) -cycloalkyl- (C 1 -C 7 ) -alkylaminocarbonyl- (C 1 -C 7 ) -alkylaminocarbonyl, (C 2 -C 7 ) -alkenyl- (C 1 -C 7 ) - alkylaminocarbonyl, (C 2 -C 7 ) -alkenylaminocarbonyl- (C 1 -C 7 ) -alkyl, (C 2 -C 7 ) -alkenyl- (C 1 -C 7 ) -alkylaminocarbonyl- (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -alkylcarbonyL (C3-C7) - cycloalkylcarbonyl, arylcarbonyl, formyl, hydroxyiminomethyl,
Aminoiminomethyl, (Ci-C7)-Alkoxyiminomethyl, (Ci-C7)-Alkylaminoiminomethyl, Bis[(Ci-C7)-alkyl]aminoiminomethyl, (C3-C7)-Cycloalkoxyiminomeihyl, (C3-C7)- Cycloalkyl-(CrC7)-alkoximinomethyl, Aryloximinomethyl, Aryl-(Ci-C7)- alkoxyiminomethyl, Aryl-(Ci-C7)-alkylaminoiminomethyl, (C2-C7)- Alkenyloxyiminomethyl, Arylaminoiminomethyl, Arylsulfonylaminoiminomethyl, Heteroaryl-(Ci-C7)-alkyl, Heterocyciyl-(Ci-C7)-alkyl, Hydroxycarbonylheterocyclyl, (Ci-C7)-Alkoxycarbonylheterocyclyl, (C2-C7)- Alkenyloxycarbonylheterocyclyl, (C2-C7)-Alkenyl-(Ci-C7)- alkoxycarbonylheterocyclyl, Aryl-(Ci-C7)-alkoxycarbonylheterocyclyl, (C3-C7)- Cycloalkoxycarbonylheterocyclyl, (C3-C7)-Cycloalkyl-(d-C7)- alkoxycarbonylheterocyclyl, Aminocarbonylheterocyclyl, (C1-C7)- Alkylaminocarbonylheterocyclyl, Bis[(CrC7)-Alkyl]aminocarbonylheterocyclyl, (C3-C7)-Cycloalkylaminocarbonylheterocyclyl, Aryl-(d-C7)- alkylaminocarbonylheterocyclyl, (C2-C7)-Alkenylaminocarbonylheterocyclyl, Hydroxycarbonylheterocyclyl-(Ci-C7)-alkyl, (Ci-C7)-Alkoxycarbonylheterocyclyl- (Ci-C7)-alkyl, Hydroxycarbonyl-(C3-C7)-cycloalkyl-(Ci-C7)-alkyl, (C1-C7)- Alkoxycarbonyl-(C3-C7)-cycloalkyl-(Ci-C7)-alkyl, Hydroxyaminocarbonyl, (Ci-C7)-Alkoxyaminocarbonyl, Aryl-(Ci-C7)-alkoxyaminocarbonyl, Heterocyclyl, (Ci-C7)-Alkylcarbonyloxy, Arylcarbonyloxy, Heteroarylcarbonyloxy, (C3-C7)- Cycloalkylcarbonyloxy, (Ci-C7)-Alkoxycarbonyloxy, (C2-C7)- Alkenyloxycarbonyloxy, Aminosulfonyi, (d-C7)-Alkoxycarbonyl-heterocyclyl-N- carbonyl, (Ci-C7)-Alkoxycarbonyl-(Ci-C7)-alkyl-heterocyclylidenaminocarbonyl, (Ci-C7)-Alkoxycarbonylheterocyclyliden-(CrC7)-alkylaminocarbonyl (C1-C7)- Alkoxycarbonyl-(Ci-C7)-Alkyl((Ci-C7)-alkyl)aminocarbonyl, (C1-C7)- Alkoxycarbonyl-(C3-C7)-cycloalkylidenaminocarbonyl, Heterocyclyl-N-carbonyl, (Ci-C7)-Alkoxy-(Ci-C7)-alkylaminocarbonyi steht, Aminoiminomethyl, (C 1 -C 7) -alkoxyiminomethyl, (C 1 -C 7) -alkylaminoiminomethyl, bis [(C 1 -C 7) -alkyl] aminoiminomethyl, (C 3 -C 7) -cycloalkoxyiminomethyl, (C 3 -C 7) -cycloalkyl- (C 1 -C 7) alkoximinomethyl, aryloximinomethyl, aryl- (C 1 -C 7 ) -alkoxyiminomethyl, aryl- (C 1 -C 7 ) -alkylaminoiminomethyl, (C 2 -C 7 ) -alkenyloxyiminomethyl, arylaminoiminomethyl, arylsulfonylaminoiminomethyl, heteroaryl- (C 1 -C 7 ) -alkyl, heterocyclic (C 1 -C 7 ) -alkyl, Hydroxycarbonylheterocyclyl, (C 1 -C 7) -alkoxycarbonylheterocyclyl, (C 2 -C 7) -alkenyloxycarbonylheterocyclyl, (C 2 -C 7) -alkenyl- (C 1 -C 7) -alkoxycarbonylheterocyclyl, aryl- (C 1 -C 7) -alkoxycarbonylheterocyclyl, (C 3 -C 7) - Cycloalkoxycarbonylheterocyclyl, (C 3 -C 7) cycloalkyl- (C 1 -C 7) alkoxycarbonylheterocyclyl, aminocarbonylheterocyclyl, (C 1 -C 7) -alkylaminocarbonylheterocyclyl, bis [(C 1 -C 7) -alkyl] aminocarbonylheterocyclyl, (C 3 -C 7) -cycloalkylaminocarbonyl-heterocyclyl, aryl (i.e. -C7) - alkylaminocarbonylheterocyclyl, (C 2 -C 7 ) -alkenylaminocarbonylheterocyclyl, hydroxycarbonylheterocyclyl- (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -alkoxycarbonylheterocyclyl- (C 1 -C 7 ) -alkyl, hydroxycarbonyl- (C 3 -C 7) - cycloalkyl- (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -alkoxycarbonyl- (C 3 -C 7 ) -cycloalkyl- (C 1 -C 7 ) -alkyl, hydroxyaminocarbonyl, (C 1 -C 7 ) -alkoxyaminocarbonyl, aryl- C 7 ) alkoxyaminocarbonyl, heterocyclyl, (C 1 -C 7 ) -alkylcarbonyloxy, arylcarbonyloxy, heteroarylcarbonyloxy, (C 3 -C 7 ) -cycloalkylcarbonyloxy, (C 1 -C 7 ) -alkoxycarbonyloxy, (C 2 -C 7 ) -alkenyloxycarbon yloxy, aminosulfonyi, (C 1 -C 7) -alkoxycarbonyl-heterocyclyl-N-carbonyl, (C 1 -C 7) -alkoxycarbonyl- (C 1 -C 7) -alkyl-heterocyclylideneaminocarbonyl, (C 1 -C 7) -alkoxycarbonylheterocyclylidene- (C 1 -C 7) -alkylaminocarbonyl ( C 1 -C 7) -alkoxycarbonyl- (C 1 -C 7) -alkyl (C 1 -C 7) -alkyl) aminocarbonyl, (C 1 -C 7) -alkoxycarbonyl- (C 3 -C 7) -cycloalkylidene-aminocarbonyl, heterocyclyl-N-carbonyl, C7) -alkoxy- (Ci-C7) -alkylaminocarbonyi,
R7, R8, R9, R10, R1 1 und R12 unabhängig voneinander für Wasserstoff, (Ci-C7)-Alkyl, (C3-C7)-Cycloalkyl, (C2-C7)-Alkenyl, (C2-C7)-Alkenyl-(Ci-C7)-alkyl, (C1-C7)- Alkoxy-(Ci-C7)-alkyl, Hydroxy-(Ci-C7)-alkyl, (Ci-C7)-Haloalkyl, (C2-C7)- Haloalkenyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-alkyl, (Ci-C7)-Alkoxy-(Ci-C7)-haloalkyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-haloalkyl, (CrC7)-Alkoxy, (CrC7)-Alkylthio, (C1-C7)- Alkylamino, Halogen, Amino stehen, wobei mindestens eine der Gruppen R7, R8, R9, R10, R1 1 und R12 nicht für Wasserstoff steht und R 7, R 8, R 9, R 10, R 1 1 and R 12 are independently hydrogen, (Ci-C7) alkyl, (C 3 -C 7) -cycloalkyl, (C 2 -C 7) - alkenyl, (C 2 -C 7) alkenyl (Ci-C7) alkyl, (C1-C7) - alkoxy (Ci-C7) alkyl, hydroxy (Ci-C 7) alkyl, ( C 1 -C 7 ) -haloalkyl, (C 2 -C 7 ) -haloalkenyl, (C 1 -C 7 ) -haloalkoxy- (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -haloalkyl , (Ci-C7) haloalkoxy (Ci-C7) haloalkyl, (CrC 7) alkoxy, (CrC 7) alkylthio, (C1-C7) - are alkylamino, halogen, amino, wherein at least one of R 7, R 8, R 9, R 10, R 1 1 and R 12 is not hydrogen, and
R3 und R4 mit dem Atom, an das sie gebunden sind, eine exo-Alkylidengruppe oder einen vollständig gesättigten, gegebenenfalls durch O (Sauerstoff), S R 3 and R 4 with the atom to which they are attached, an exo-alkylidene group or a fully saturated, optionally substituted by O (oxygen), S
(Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und (Sulfur) or a group NH, NR 37 interrupted and
gegebenenfalls weiter substituierten 3 bis 6-gliedrigen Ring bilden, R1 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, optionally form further substituted 3 to 6-membered ring, R 1 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
R1 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, R 1 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
R3 und R7 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 3 and R 7 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
R3 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, R 3 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
R1 und R3 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 1 and R 3 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
R7 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 7 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
R3 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, R7 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, R 3 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form, R 7 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
R 3, R14, R15 und R16 unabhängig voneinander für Wasserstoff, Halogen, Nitro, Amino, Cyano, (CrC7)-Alkyl, Aryl, Heteroaryl, (C3-C7)-Cycloalkyl, (C4-C7)-Cycloalkenyl, (C2-C7)-Alkenyl, (C2-C7)-Alkinyl, (C2-C7)-Alkenyl-(Ci-C7)-alkyl, (C2-C7)-Alkinyl- (Ci-C7)-alkyl, Hydroxy, (Ci-C7)-Alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkoxy, (C1-C7)- Alkoxy-(d-C7)-alkyl, Hydroxy-(d-C7)-alkyl, (d-C7)-Haloalkoxy, (C1-C7)- Haloalkyl, (C2-C7)-Haloalkenyl, (C2-C7)-Haloalkinyl, (Ci-C7)-Haloalkoxy-(Ci-C7)- alkyl, (Ci-C7)-Alkoxy-(Ci-C7)-haloalkyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-haloalkyl, Hydrothio, (d-C7)-Alkylthio, (d-C7)-Haloalkylthio, (Ci-C7)-Alkylthio-(Ci-C7)- alkyl, (CrC7)-Haloalkylthio-(Ci-C7)-alkyl, (Ci-C7)-Alkylamino, Bis-[(d-C7)- alkyljamino, (C2-C7)-Alkenylamino, (C3-C7)-Cycloalkylamino, (d-C7)- Alkylcarbonylamino, (C3-C7)-Cycloalkylcarbonylamino, Arylcarbonylamino, Heteroarylcarbonylamino, Formylamino, (Ci-C7)-Haloalkylcarbonylamino, R 3, R 14, R 15 and R 16 are independently hydrogen, halogen, nitro, amino, cyano, (CrC 7) alkyl, aryl, heteroaryl, (C 3 -C 7) cycloalkyl, (C 4 -C 7) cycloalkenyl, (C2-C7) alkenyl, (C 2 -C 7) -alkynyl, (C2-C7) alkenyl (Ci-C7) alkyl, (C 2 -C 7) - Alkynyl- (C 1 -C 7 ) -alkyl, hydroxy, (C 1 -C 7 ) -alkoxy, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -alkoxy, (C 1 -C 7 ) -alkoxy- (dC 7) alkyl, hydroxy (dC 7) alkyl, (dC 7) -haloalkoxy, (C1-C7) - haloalkyl, (C 2 -C 7) haloalkenyl, (C 2 -C 7) haloalkynyl, ( Ci-C7) haloalkoxy (Ci-C7) - alkyl, (Ci-C7) alkoxy (Ci-C7) haloalkyl, (Ci-C7) haloalkoxy (Ci-C 7) haloalkyl, Hydrothio, (dC 7) alkylthio, (dC 7) haloalkylthio, (Ci-C7) -alkylthio (Ci-C 7) - alkyl, (CrC 7) -Haloalkylthio- (Ci-C 7) alkyl, (Ci-C7) alkylamino, bis - [(dC 7) - alkyljamino, (C 2 -C 7) alkenylamino, (C3-C7) cycloalkylamino, (dC 7) - alkylcarbonylamino, (C3 -C 7 ) -cycloalkylcarbonylamino, arylcarbonylamino, heteroarylcarbonylamino, formylamino, (C 1 -C 7 ) -haloalkylcarbon ylamino,
(Ci-C7)-Alkoxycarbonylamino, (Ci-C7)-Alkylaminocarbonylamino, (C1-C7)- Alkyl[(Ci-C7)-Alkyl]aminocarbonylamino, (Ci-C7)-Alkylsulfonylamino, (C3-C7)- Cycloalkylsulfonylamino, Arylsulfonylamino, Hetarylsulfonylamino, Sulfonyl- (Ci-C7)-haloalkylamino, Amino-(Ci-C7)-alkylsulfonyl, Amino-(Ci-C7)- haloalkylsulfonyl, (d-C7)-Alkylaminosulfonyl, Bis[(d-C )-alkyl]aminosulfonyl, (C3-C7)-Cycloalkylaminosulfonyl, (Ci-C7)-Haloalkylaminosulfonyl, (C 1 -C 7 ) -alkoxycarbonylamino, (C 1 -C 7 ) -alkylaminocarbonylamino, (C 1 -C 7 ) -alkyl [(C 1 -C 7 ) -alkyl] aminocarbonylamino, (C 1 -C 7 ) -alkylsulfonylamino, (C 3 -C 7 ) ) - cycloalkylsulfonylamino, arylsulfonylamino, Hetarylsulfonylamino, sulfonyl (Ci-C 7) -haloalkylamino, amino (Ci-C7) alkylsulfonyl, amino (Ci-C7) - haloalkylsulfonyl, (dC 7) alkylaminosulfonyl, bis [ (C 1 -C 4) -alkyl] aminosulfonyl, (C 3 -C 7 ) -cycloalkylaminosulfonyl, (C 1 -C 7 ) -haloalkylaminosulfonyl,
Heteroarylaminosulfonyl, Arylaminosulfonyl, Aryl-(Ci-C7)-alkylaminosulfonyl, (d-C7)-Alkylsulfonyl, (C3-C7)-Cycloalkylsulfonyl, Arylsulfonyl, Hydroxycarbonyl, (Ci-C7)-Alkoxycarbonyl, (C3-C7)-Cycloalkoxycarbonyl, (C3-C7)-Cycloalkyl- (Ci-C7)-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C7)-alkoxycarbonyl, (C2-C7)- Alkenyloxycarbonyl, (C2-C7)-Alkinyloxycarbonyl, Aminocarbonyl, (C1-C7)- Alkylaminocarbonyl, Bis[(Ci-C7)-alkyl]aminocarbonyl, (Ci-C7)-Alkyl[(Ci-C7)- Alkyljaminocarbonyl, (Ci-C7)-Alkyl[(Ci-C7)-Alkoxy]aminocarbonyl, (C2-C )- Alkenylaminocarbonyl, (C3-C7)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(CrC )-alkylaminocarbonyl stehen, A\ A2, A3 und A4 gleich oder verschieden sind und unabhängig voneinander für NHeteroarylaminosulfonyl, arylaminosulfonyl, aryl- (Ci-C7) alkylaminosulfonyl, (dC 7) alkylsulfonyl, (C3-C7) cycloalkylsulfonyl, arylsulfonyl, hydroxycarbonyl, (Ci-C 7) alkoxycarbonyl, (C 3 -C 7 ) -cycloalkoxycarbonyl, (C3-C7) -cycloalkyl- (Ci-C 7) alkoxycarbonyl, aryloxycarbonyl, aryl- (Ci-C7) -alkoxycarbonyl, (C2-C7) - alkenyloxycarbonyl, (C 2 -C 7) Alkynyloxycarbonyl, aminocarbonyl, (C 1 -C 7 ) -alkylaminocarbonyl, bis [(C 1 -C 7 ) -alkyl] aminocarbonyl, (C 1 -C 7 ) -alkyl [(C 1 -C 7 ) -alkylaminocarbonyl, (C 1 -C 7 ) Alkyl [(C 1 -C 7 ) alkoxy] aminocarbonyl, (C 2 -C) -alkenylaminocarbonyl, (C 3 -C 7 ) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 4 ) -alkylaminocarbonyl, A \ A 2 , A 3 and A 4 are the same or different and are independently N
(Stickstoff) oder die Gruppierungen C-H, C-CH3, C-F, C-Cl, C-Br, Ol, OOCF3, C-OCH3, C-CF3, C-CO2H, C-CO2CH3 stehen, wobei jedoch in keinem Fall mehr als zwei N-Atome benachbart sind, (Nitrogen) or the groups CH, C-CH 3 , CF, C-Cl, C-Br, Ol, OOCF 3 , C-OCH 3, C-CF 3 , C-CO 2 H, C-CO 2 CH 3 , but in no Case more than two N atoms are adjacent,
R17 und R18 unabhängig voneinander für Wasserstoff, Halogen, (d-C7)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (C3-C7)-Cycloalkyl, (C2-C7)-Alkenyl, (C2-C7)-Alkinyl, (O-O)-Alkoxy, (Ci-C7)-Alkoxy-(d-C7)-alkyl, Aryloxy-(d-C7)-alkyl, (C1-C7)- Haloalkoxy, (Ci-C7)-Haloalkyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-alkyl, (Ci-O)-Alkoxy- (Ci-C7)-haloalkyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-haloalkyl, (Ci-C7)-Alkylthio, (d-C7)-Haloalkylthio, (0-C7)-Alkylthio-(0-C7)-alkyl, Hydroxycarbonyl, (O-O)- Alkoxycarbonyl, (C3-C7)-Cycloalkoxycarbonyl, (C3-C7)-Cycloalkyl-(0-C7)- alkoxycarbonyl, Aryloxycarbonyl, Aryl-(d-C7)-alkoxycarbonyl, (C2-C7)- Alkenyloxycarbonyl, (C2-C7)-Alkinyloxycarbonyl, Aminocarbonyl, (O-O)- Alkylaminocarbonyl, Bis[(Ci-C7)-alkyl]aminocarbonyl, (0-C7)-Alkyl[(0-C7)- Alkyl]aminocarbonyl, (CrC7)-Alkyl[(Ci-C7)-Alkoxy]aminocarbonyl, (C2-C7)- Alkenylaminocarbonyl, (C3-C7)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C7)-alkylaminocarbonyl stehen, R 17 and R 18 are independently hydrogen, halogen, (dC 7) alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 7) cycloalkyl, (C 2 -C 7) alkenyl, (C 2 -C 7 ) alkynyl, (OO) alkoxy, (C 1 -C 7 ) alkoxy (C 1 -C 7 ) -alkyl, aryloxy (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -haloalkoxy, (C 1 -C 7 ) Haloalkyl, (C 1 -C 7 ) -haloalkoxy- (C 1 -C 7 ) -alkyl, (C 1 -C 4) -alkoxy- (C 1 -C 7 ) -haloalkyl, (C 1 -C 7 ) -haloalkoxy- (C 1 -C 4 ) -alkyl C 7) -haloalkyl, (Ci-C7) -alkylthio, (dC 7) haloalkylthio, (0-C 7) alkylthio (0-C 7) alkyl, hydroxycarbonyl, (OO) - alkoxycarbonyl, (C3 -C 7) cycloalkoxycarbonyl, (C3-C7) -cycloalkyl- (0-C 7) - alkoxycarbonyl, aryloxycarbonyl, aryl (dC 7) -alkoxycarbonyl, (C2-C7) - alkenyloxycarbonyl, (C2-C7) alkynyloxycarbonyl, aminocarbonyl, (OO) - alkylaminocarbonyl, bis [(Ci-C 7) alkyl] aminocarbonyl, (0-C 7) alkyl [(0-C 7) - alkyl] aminocarbonyl, (CrC 7) alkyl [(C 1 -C 7 ) -alkoxy] aminocarbonyl, (C 2 -C 7 ) -alkenylaminocarbonyl, (C 3 -C 7 ) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 7 ) -alkylaminocarbonyl,
A5 für S (Schwefel), O (Sauerstoff) oder die Gruppierungen N-H, N-CH3, N-CH2CH3, N- CH(CH3)2, N-C02t-Bu, N-Aryl, N-Heteroaryl, N-Heterocyclyl steht, A 5 represents S (sulfur), O (oxygen) or the groupings NH, N-CH 3 , N-CH 2 CH 3 , N-CH (CH 3 ) 2 , N-CO 2 t-Bu, N-aryl, N-heteroaryl, N-heterocyclyl is
R19, R20, R23 und R24 unabhängig voneinander für Wasserstoff, (Ci-C7)-Alkyl, Halogen, (C3-C7)-Cycloalkyl, Aryl, Heteroaryl, Heterocyclyl, (C2-C7)-Alkenyl, (C2-C7)- Alkenyl-(C,-C7)-alkyl, Aryl-(d-C7)-alkyl, (d-C7)-Alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)- alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkyl, Hydroxy, (d-C7)-Haloalkyl, (C1-C7)- Haloalkylthio stehen, R 19, R 20, R 23 and R 24 are independently hydrogen, (Ci-C7) alkyl, halogen, (C 3 -C 7) cycloalkyl, aryl, heteroaryl, heterocyclyl, (C 2 -C 7) alkenyl, (C 2 -C 7) - alkenyl, (C, -C7) alkyl, aryl (dC 7) alkyl, (dC 7) alkoxy, (Ci-C7) alkoxy (Ci -C 7) - alkoxy, (Ci-C7) alkoxy (Ci-C7) alkyl, hydroxy, (dC 7) -haloalkyl, (C1-C7) - haloalkylthio stand,
R19 und R23 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 19 and R 23 with the atoms to which they are attached form a completely saturated or partially saturated, optionally further substituted 5 to 7-membered ring,
A6, A7 gleich oder verschieden sind und unabhängig voneinander für O (Sauerstoff), S (Schwefel), N-H, N-OCH3, N-CH3 oder die Gruppierung CR21R22 stehen, wobei jedoch in keinem Fall zwei N-, O- oder S-Atome benachbart sind, und wobei R21 und R22 in der Gruppierung CR21R22 jeweils gleiche oder verschiedene A 6 , A 7 are identical or different and independently of one another represent O (oxygen), S (sulfur), NH, N-OCH 3, N-CH 3 or the group CR 21 R 22 , where however, in no case are two N, O or S atoms adjacent, and wherein R 21 and R 22 in the group CR 21 R 22 are each the same or different
Bedeutungen gemäß der nachstehenden Definition haben und und R22 unabhängig voneinander für Wasserstoff, Halogen, (Ci-C7)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (C3-C7)-Cycloalkyl, (C2-C7)-Alkenyl, (Ci-C7)-Alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkyl, Aryloxy-(Ci-C7)-alkyl, (d-C7)-Haloalkoxy, (C1-C7)- Haloalkyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-alkyl, (Ci-C7)-Alkoxy-(d-C7)-haloalkyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-haloalkyl, (Ci-C7)-Alkylthio, (Ci-C7)-Haloalkylthio, (Ci-C7)-Alkylthio-(Ci-C7)-alkyl, Hydroxycarbonyl, (Ci-C7)-Alkoxycarbonyl, Have meanings as defined below and R 22 and are independently hydrogen, halogen, (Ci-C 7) alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 7) cycloalkyl, (C 2 -C 7) - Alkenyl, (C 1 -C 7 ) -alkoxy, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -alkyl, aryloxy- (C 1 -C 7 ) -alkyl, (C 1 -C 4 ) -haloalkoxy, (C 1 -C 4 ) -alkoxy C7) - haloalkyl, (C 1 -C 7 ) -haloalkoxy- (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -alkoxy- (C 1 -C 4 ) -haloalkyl, (C 1 -C 7 ) -haloalkoxy- (Ci -C 7) haloalkyl, (Ci-C7) -alkylthio, (Ci-C 7) haloalkylthio, (Ci-C7) -alkylthio (Ci-C 7) alkyl, hydroxycarbonyl, (Ci-C 7 ) alkoxycarbonyl,
(C3-C7)-Cycloalkoxycarbonyl, (C3-C )-Cycloalkyl-(CrC7)-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C7)-alkoxycarbonyl, (C2-C7)-Alkenyloxycarbonyl, (C2-C7)-Alkinyloxycarbonyl, Aminocarbonyl, (Ci-C7)-Alkylaminocarbonyl, Bis[(CrC7)-alkyl]aminocarbonyl, (Ci-C7)-Alkyl[(CrC7)-Alkyl]aminocarbonyl, (Ci-C7)-Alkyl[(CrC )-Alkoxy]aminocarbonyl, (C2-C7)-Alkenylaminocarbonyl, (C3-C )-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(d-C7)- alkylaminocarbonyl, Amino, (d-C7)-Alkylamino, (C-3-C7)-Cycloalkylamino, Bis- [(Ci-C7)-Alkyl]amino stehen, R25, R26, R28 und R29 unabhängig voneinander für Wasserstoff, (Ci-C7)-Alkyl, Halogen, (C3-C7)-Cycloalkyl, Aryl, Heteroaryl, Heterocyclyl, (C2-C7)-Alkenyl, Aryl-(d-C7)- alkyl, (Ci-C7)-Alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)- alkyl, (Ci-C7)-Haloalkyl stehen, A8 für O (Sauerstoff), S (Schwefel), N-H, N-CH3, N-OCH3 oder die Gruppierung CHR27 steht und wobei R27 in der Gruppierung CHR27 die Bedeutung gemäß der nachstehenden Definition hat, (C3-C 7) cycloalkoxycarbonyl, (C3-C) cycloalkyl (CrC 7) alkoxycarbonyl, aryloxycarbonyl, aryl- (Ci-C7) -alkoxycarbonyl, (C2-C7) alkenyloxycarbonyl, (C2-C 7 ) -Alkinyloxycarbonyl, aminocarbonyl, (Ci-C 7 ) -alkylaminocarbonyl, bis [(CrC 7 ) -alkyl] aminocarbonyl, (Ci-C 7 ) -alkyl [(CrC 7 ) -alkyl] aminocarbonyl, (Ci-C 7 ) -Alkyl [(C 1 -C 4) -alkoxy] -aminocarbonyl, (C 2 -C 7 ) -alkenylaminocarbonyl, (C 3 -C 4) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 7 ) -alkylaminocarbonyl, amino, (C 1 -C 7 ) -alkylamino, ( C 3 -C 7 -cycloalkylamino, bis- [(C 1 -C 7 ) -alkyl] -amino, R 25 , R 26 , R 28 and R 29 independently of one another represent hydrogen, (C 1 -C 7 ) -alkyl, Halogen, (C 3 -C 7 ) -cycloalkyl, aryl, heteroaryl, heterocyclyl, (C 2 -C 7 ) -alkenyl, aryl- (dC 7 ) -alkyl, (C 1 -C 7 ) -alkoxy, (Ci-C 7) alkoxy (Ci-C7) alkoxy, (Ci-C7) alkoxy (Ci-C7) - alkyl, (Ci-C7) haloalkyl are, A 8 (for O is oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the moiety CHR 27 and wherein R 27 in the moiety CHR 27 has the meaning as defined below,
R27 für Wasserstoff, Halogen, (Ci-C7)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (C3-C7)- Cycloalkyl, (C2-C7)-Alkenyl, (d-C7)-Alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkyl,R 27 is hydrogen, halogen, (Ci-C 7) alkyl, aryl, heteroaryl, heterocyclyl, (C3-C7) - cycloalkyl, (C 2 -C 7) alkenyl, (dC 7) alkoxy, (Ci- C 7 ) -alkoxy- (C 1 -C 7 ) -alkyl,
Aryloxy-(d-C7)-alkyl, (d-C7)-Haloalkoxy, (Ci-C7)-Haloalkyl, (Ci-C7)-Alkoxy- (d-C7)-haloalkyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-haloalkyl, (d-C7)-Alkylthio, Aryloxy (dC 7) alkyl, (dC 7) haloalkoxy, (Ci-C7) haloalkyl, (Ci-C7) alkoxy (dC 7) -haloalkyl, (Ci-C7) haloalkoxy (C 1 -C 7 ) -haloalkyl, (C 1 -C 4 ) -alkylthio,
(Ci-C7)-Haloalkylthio, (CrC7)-Alkylthio-(Ci-C7)-alkyl, Hydroxycarbonyl, (C1-C7)- Alkoxycarbonyl, (C3-C7)-Cycloalkoxycarbonyl, Aryl-(d-C7)-alkoxycarbonyl, (C2-C-7)-Alkenyloxycarbonyl, (C2-C7)-Alkinyloxycarbonyl, Aminocarbonyl, (Ci-C 7) haloalkylthio, (CrC 7) alkylthio (Ci-C 7) alkyl, hydroxycarbonyl, (C1-C7) - alkoxycarbonyl, (C3-C 7) cycloalkoxycarbonyl, aryl (dC 7) alkoxycarbonyl, (C 2 -C 7) -alkenyloxycarbonyl, (C 2 -C 7) -alkynyloxycarbonyl, aminocarbonyl,
(Ci-C7)-Alkylaminocarbonyl, Bis[(CrC7)-alkyl]aminocarbonyl, (C1-C7)- Alkyl[(Ci-C7)-Alkyl]aminocarbonyl, (Ci-C7)-Alkyl[(Ci-C7)-Alkoxy]aminocarbonyl, (C2-C7)-Alkenylaminocarbonyl, (C3-C7)-Cycloalkylaminocarbonyl,  (C 1 -C 7) -alkylaminocarbonyl, bis [(C 1 -C 7) -alkyl] aminocarbonyl, (C 1 -C 7) -alkyl [(C 1 -C 7) -alkyl] aminocarbonyl, (C 1 -C 7) -alkyl [(C 1 -C 7)] Alkoxy] aminocarbonyl, (C 2 -C 7) -alkenylaminocarbonyl, (C 3 -C 7) -cycloalkylaminocarbonyl,
Arylaminocarbonyl, Aryl-(Ci-C7)-alkylaminocarbonyl, Amino, (Ci-C7)-Alkylamino, (C3-C7)-Cycloalkylamino, Bis-[(Ci-C7)-Alkyl]amino steht,  Arylaminocarbonyl, aryl- (C 1 -C 7) -alkylaminocarbonyl, amino, (C 1 -C 7) -alkylamino, (C 3 -C 7) -cycloalkylamino, bis- [(C 1 -C 7) -alkyl] -amino,
R30, R31 , R32, R34, R35 und R36 unabhängig voneinander für Wasserstoff, (Ci-C7)-Alkyl, Halogen, (C-3-C7)-Cycloalkyl, Aryl, Heteroaryl, Heterocyclyl, (C2-C7)-Alkenyl, (Ci-C7)-Alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkyl, (Ci-C7)-Haloalkyl, (Ci-C7)-Alkylthio, (CrC7)-Haloalkylthio stehen, R 30 , R 31 , R 32 , R 34 , R 35 and R 36 independently of one another represent hydrogen, (C 1 -C 7 ) -alkyl, halogen, (C 3 -C 7 ) -cycloalkyl, aryl, heteroaryl, heterocyclyl, ( C 2 -C 7 ) -alkenyl, (C 1 -C 7 ) -alkoxy, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -alkoxy, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -alkyl, (Ci-C7) haloalkyl, (Ci-C7) alkylthio, (CrC 7) are haloalkylthio,
A9 für O (Sauerstoff), S (Schwefel), N-H, N-CH3, N-OCH3 oder die Gruppierung CHR33 steht und wobei R33 in der Gruppierung CHR33 die Bedeutung gemäß der nachstehenden Definition hat und A 9 is O (oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the group CHR 33 , and wherein R 33 in the group CHR 33 has the meaning as defined below and
R33 für Wasserstoff, Halogen, (d-C7)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (C3-C7)- Cycloalkyl, (C2-C7)-Alkenyl, (Ci-C7)-Alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkyl, Aryloxy-(Ci-C7)-alkyl, (Ci-C7)-Haloalkoxy, (Ci-C7)-Haloalkyl, (Ci-C7)-Alkylthio, (Ci-C7)-Haloalkylthio, Hydroxycarbonyl, (Ci-C7)-Alkoxycarbonyl, (C3-C7)- Cycloalkoxycarbonyl, Aryl-(d-C7)-alkoxycarbonyl, (C2-C7)-Alkenyloxycarbonyl, (C2-C7)-Alkinyloxycarbonyl, Aminocarbonyl, (Ci-C7)-Alkylaminocarbonyl, Bis[(d-C7)-alkyl]aminocarbonyl, (Ci-C7)-Alkyl[(CrC7)-Alkyl]aminocarbonyl, (Ci-C7)-Alkyl[(CrC7)-Alkoxy]aminocarbonyl, (C2-C7)-Alkenylaminocarbonyl, (C3-C7)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C7)- alkylaminocarbonyl, Amino, (Ci-C-7)-Alkylamino, (C3-C7)-Cycloalkylamino, Bis- [(Ci-C7)-Alkyl]amino steht, R 33 is hydrogen, halogen, (C 1 -C 7 ) -alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 7 ) -cycloalkyl, (C 2 -C 7 ) -alkenyl, (C 1 -C 7 ) -alkoxy, (Ci -C 7) alkoxy (Ci-C7) alkyl, aryloxy (Ci-C7) alkyl, (Ci-C7) haloalkoxy, (Ci-C7) haloalkyl, (Ci-C 7) Alkylthio, (C 1 -C 7) -haloalkylthio, hydroxycarbonyl, (C 1 -C 7) -alkoxycarbonyl, (C 3 -C 7) -cycloalkoxycarbonyl, aryl- (C 1 -C 7) -alkoxycarbonyl, (C 2 -C 7) -alkenyloxycarbonyl, (C 2 -C 7) -alkoxycarbonyl, C7) alkynyloxycarbonyl, aminocarbonyl, (C 1 -C 7) -alkylaminocarbonyl, bis [(C 1 -C 4) -alkyl] aminocarbonyl, (C 1 -C 7) -alkyl [(C 1 -C 7) -alkyl] aminocarbonyl, (C 1 -C 7) -alkyl [(C 1 -C 7) -alkoxy] aminocarbonyl, (C 2 -C 7) -alkenylaminocarbonyl, (C 3 -C 7) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 7) -alkylaminocarbonyl, amino, (C 1 -C-7) -alkylamino, (C 3 -C 7) -cycloalkylamino, bis- [(C 1 -C 7 ) -alkyl] -amino,
R37 für (Ci-C7)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (C3-C7)-Cycloalkyl, (C2-C7)-Alkenyl, (Ci-C7)-Alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkyl, Aryloxy-(Ci-C7)-alkyl, (C1-C7)- Alkoxycarbonyl, (C3-C7)- Cycloalkoxycarbonyl, Aryl-(Ci-C7)-alkoxycarbonyl, (C2-C7)-Alkenyloxycarbonyl, (C2-C7)-Alkinyloxycarbonyl, (Ci-C7)-Alkylcarbonyl, (C3-C7)-Cycloalkylcarbonyl, Arylcarbonyl, Heteroarylcarbonyl steht. Ganz besonders bevorzugt ist die erfindungsgemäße Verwendung von Verbindungen der allgemeinen Formel (I), worin R 37 is (Ci-C7) alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 7) cycloalkyl, (C2-C7) alkenyl, (Ci-C7) alkoxy, (Ci-C7 ) Alkoxy- (C 1 -C 7 ) -alkyl, aryloxy- (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -alkoxycarbonyl, (C 3 -C 7 ) -cycloalkoxycarbonyl, aryl- (C 1 -C 7 ) -alkoxycarbonyl, (C 2 -C 7) alkenyloxycarbonyl, (C 2 -C 7) -alkynyloxycarbonyl, (C 1 -C 7) -alkylcarbonyl, (C 3 -C 7) -cycloalkylcarbonyl, arylcarbonyl, heteroarylcarbonyl. Very particular preference is given to the use according to the invention of compounds of the general formula (I) in which
[X-Y] für die Gruppierungen [X-Y] for the groupings
EX-Y]1 steht, EX-Y] 1 ,
Q für die Gruppierungen Q-1 bis Q-6 Q for the groupings Q-1 to Q-6
Q-1 Q-2 Q-3  Q-1 Q-2 Q-3
Q-4 , Q-5 und Q-6 steht, wobei R13, R14, R15, R16, R17, R18, R19, R20, R23, R24, R25, R26, R28, R29, R30, R31, R32, R34, R35 und R36 sowie A1 bis A9 jeweils die Bedeutung gemäß der nachstehenden Definitionen haben und wobei der Pfeil für eine Bindung zur jeweiligen Gruppierung C-R6 in der allgemeinen Formel (I) steht, Q-4, Q -5 and Q -6, where R 13 , R 14 , R 15 , R 16 , R 17 , R 18 , R 19 , R 20 , R 23 , R 24 , R 25 , R 26 , R 28 , R 29 , R 30 , R 31 , R 32 , R 34 , R 35 and R 36 and A 1 to A 9 are each as defined below and wherein the arrow indicates a bond to the respective grouping CR 6 in the general formula (I) stands,
R1 für (Ci-C6)-Alkyl, (C3-C6)-Cycloalkyl, (C4-C6)-Cycloalkenyl, (C2-C6)-Alkenyl, (C2-C6)-Alkinyl, (C2-C6)-Alkenyl-(Ci-C6)-alkyl, (C2-C6)-Alkinyl-(Ci-C6)-alkyl, R 1 is (C 1 -C 6 ) -alkyl, (C 3 -C 6 ) -cycloalkyl, (C 4 -C 6 ) -cycloalkenyl, (C 2 -C 6 ) -alkenyl, (C 2 -C 6 ) - Alkynyl, (C 2 -C 6 ) -alkenyl- (C 1 -C 6 ) -alkyl, (C 2 -C 6 ) -alkynyl- (C 1 -C 6 ) -alkyl,
(Ci-C6)-Alkoxy-(Ci-C6)-alkyl, Hydroxy-(Ci-Cr>)-alkyl, (Ci-C6)-Haloalkyl, (C2-C6)- Haloalkenyl, (C2-C6)-Haloalkinyl steht, (Ci-C6) alkoxy (Ci-C 6) alkyl, hydroxy (Ci-Cr>) alkyl, (Ci-C 6) -haloalkyl, (C 2 -C 6) - haloalkenyl, (C2- C6) -haloalkynyl,
R2, R3 und R4 unabhängig voneinander für Wasserstoff, Fluor, Chlor, Brom, lod, R 2 , R 3 and R 4 independently of one another represent hydrogen, fluorine, chlorine, bromine, iodine,
(CrC6)-Alkyl, (C3-C6)-Cycloalkyl, (C4-C6)-Cycloalkenyl, (C2-C6)-Alkenyl, (C2-C6)- Alkinyl, (C2-C7)-Alkenyl-(Ci-C7)-alkyl, (C2-C7)-Alkinyl-(Ci-C7)-alkyl, (C1-C7)- Alkoxy-(Ci-C7)-alkyl, Hydroxy-(Ci-C7)-alkyl, (Ci-C7)-Haloalkyl stehen, (C 1 -C 6 ) -alkyl, (C 3 -C 6 ) -cycloalkyl, (C 4 -C 6 ) -cycloalkenyl, (C 2 -C 6 ) -alkenyl, (C 2 -C 6 ) - Alkynyl, (C2-C7) alkenyl (Ci-C7) alkyl, (C 2 -C 7) alkynyl (Ci-C7) alkyl, (C1-C7) - alkoxy (Ci-C 7 ) -alkyl, hydroxy- (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -haloalkyl,
R5 für Hydroxy, (Ci-Cc)-Alkoxy, Aryloxy, (C3-C6)-Cycloalkyloxy, (C2-C6)-Alkenyloxy, (C2-C6)-Alkenyl-(Ci-C6)-alkyloxy, (Ci-C6)-Aikoxy-(Ci-C6)-alkyloxy, (Ci-C6)- Alkylcarbonyloxy, Arylcarbonyloxy, Heteroarylcarbonyloxy, (C3-G3)- Cycloalkylcarbonyloxy, (CrC6)-Alkoxycarbonyloxy, (C2-C6)- Alkenyloxycarbonyloxy, Aryloxy-(Ci-C6)-alkyloxy, Aryl-(Ci-C6)-alkyloxy, (d-Ce)- Alkoxy-(Ci-C6)-alkoxy-(Ci-C6)-alkyloxy, (Ci-C6)-Alkylthio-(Ci-C6)-alkyloxy, Tris[(Ci-C6)-alkyl]silyloxy, (Ci-C6)-Alkyl-Bis[(Ci-C6)-alkyl]silyloxy, (Ci-Ce)-Alkyl- bis(Aryl)silyloxy, Aryl-bis[(d-C6)— aikyljsüyioxy, Cycloalkyl-bis[(Ci-C6)- alkyljsilyloxy, Halo-bis[(Ci-C6)-alkyl]silyloxy, Tns[(Ci-C6)-alky!]siiyi-(Ci-C6)- alkoxy-(Ci-C6)-alkyloxy, steht, R 5 is hydroxy, (C 1 -C 6 ) -alkoxy, aryloxy, (C 3 -C 6 ) -cycloalkyloxy, (C 2 -C 6 ) -alkenyloxy, (C 2 -C 6 ) -alkenyl- (C 1 -C 6 ) -alkyloxy, ( C 1 -C 6 -alkoxy- (C 1 -C 6 ) -alkyloxy, (C 1 -C 6 ) -alkylcarbonyloxy, arylcarbonyloxy, heteroarylcarbonyloxy, (C 3 -G 3) -cycloalkylcarbonyloxy, (C 1 -C 6 ) -alkoxycarbonyloxy, (C 2 -C 6 ) Alkenyloxycarbonyloxy, aryloxy- (C 1 -C 6 ) -alkyloxy, aryl- (C 1 -C 6 ) -alkyloxy, (d-Ce) -alkoxy- (C 1 -C 6 ) -alkoxy- (C 1 -C 6 ) -alkyloxy, C 6) alkylthio (Ci-C 6) alkyloxy, tris [(Ci-C6) alkyl] silyloxy, (Ci-C6) alkyl-bis [(Ci-C6) alkyl] silyloxy ( Ci-Ce) -alkyl bis (aryl) silyloxy, aryl-bis [(d-C6) -alkylsilyloxy, cycloalkyl-bis [(Ci-C6) alkylsilyloxy, halo-bis [(Ci-C 6 ) alkyl] silyloxy, Tns [(Ci-C 6 ) -alky!] siiyi- (Ci-C 6 ) - alkoxy- (Ci-C6) -alkyloxy, is,
R6 für Nitro, Amino, Hydroxy, Hydrothio, Thiocyanato, Isothiocyanato, Fluor, Chlor,R 6 for nitro, amino, hydroxy, hydrothio, thiocyanato, isothiocyanato, fluorine, chlorine,
Brom, lod, (Ci-C6)-Alkyl, (C3-C6)-Cycloalkyl, (C2-C6)-Alkenyl, (C4-C6)- Cycloalkenyl, (C2-C6)-Alkinyl, Aryl-(C2-Cö)-alkinyl, Tris[(Ci-C6)-alkyl]silyl-(C2-C6)- alkinyl, Aryl, Aryl-(Ci-C6)-alkyl, Aryl-(Ci-C6)-alkoxy, Heteroaryl, (Ci-Ce)- Haloalkyl, (C3-C6)-Halocycloalkyl, (C2-C6)-Haloalkenyl, (Ci-C6)-Alkoxy, (Ci-C6)- Haloalkoxy, Aryloxy, Heteroaryloxy, (C3-C6)-Cycloalkyloxy, (C3-C6)-Cycloalkyl- (Ci-C6)-alkoxy, (C2-C6)- (C2-C6)-Alkenyloxy, (C2-C6)-Alkinyl-(C2-C6)-alkyloxy, Hydroxy-(Ci-C6)-alkyl, (Ci-C6)-Alkoxy-(Ci-C6)-alkyl, Aryloxy-(CrC6)-alkyl, Heteroaryloxy-(Ci-C6)-alkyl, (CrC6)-Alkylthio, (Ci-C6)-Haloalkylthio, (Ci-C6)- Alkoxycarbonyl-(Ci-C6)-alkylthio, Aryithio, (Cs-CeJ-Cycloalkylthio, Heteroaryithio, (Ci-C6)-Alkylthio-(Ci-C6)-alkyl, (Ci-C6)-Alkylamino, Bis[(Ci-C6)-alkyl]amino, (C2-C6)-Alkenylamino, (C3-C6)-Cycloalkylamino, (Ci-Cc -Alkylcarbonylamino, (C3-C6)-Cycloalkylcarbonylamino, Arylcarbonylamino, Heteroarylcarbonylamino, Formylamino, (Ci-C6)-Haloalkylcarbonylamino, (Ci-C6)-Alkoxycarbonylamino, (Ci-C6)-Alkylaminocarbonylamino, (Ci-C6)-Alkyl[(Ci-C6)- Alkyl]aminocarbonylamino, (Ci-C6)-Alkylsulfonylamino, (C3-C6)- Cycloalkylsulfonylamino, Arylsulfonylamino, Hetarylsulfonylamino, Sulfonyl- (CrC6)-haloalkylamino, Amino-(Ci-C6)-alkylsulfonyl, Amino-(Ci-C6)- haloalkylsulfonyl, (Ci-CeJ-Alkylaminosulfonyl, Bis[(Ci-C6)-alkyl]aminosulfonyl, (C3-C6)-Cycloalkylaminosulfonyl, (Ci-C6)-Haloalkylaminosulfonyl, Heteroarylaminosulfonyl, Arylaminosulfonyl, Aryl-(Ci-C6)-alkylaminosulfonyl, (Ci-C6)-Alkylsulfonyl, (C3-C6)-Cycioalkylsulfonyl, Arylsulfonyl, (Ci-C6)- Alkylsulfinyl, (C3-C6)-Cycloalkylsulfinyl, Arylsulfinyl, N.S-Bis[(d-C6)- alkyl]sulfonimidoyl, S-(Ci-Cc>)-Alkylsulfonimidoyl, (d-Ce)- Alkylsulfonylaminocarbonyl, (C3-C6)-Cycloalkylsulfonylaminocarbonyl, Aryl- (CrCeJ-alkylcarbonylamino, (C3-C6)-Cycloalkyl-(CrC6)-alkylcarbonylamino, Heteroarylcarbonylamino, (Ci-C6)-Alkoxy-(Ci-Cö)-alkylcarbonylamino, Hydroxy- (Ci-C6)-alkylcarbonylamino, (Ci-C6)-Alkoxycarbonylamino-(Ci-C6)- alkylcarbonylamino, Cyano, Cyano-(Ci-Ce)-alkyl, Hydroxycarbonyl, (Ci-Ce)- Alkoxycarbonyl, (C3-Cr>)-Cycloalkoxycarbonyl, (C3-Cr>)-Cycloalkyl-(Ci-C6)- alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C6)-alkoxycarbonyl, (C2-Ce)- Alkenyloxycarbonyl, (C2-Cr>)-Alkinyloxycarbonyl, (Ci-CeJ-Haloalkyloxycarbonyl, (Ci-C6)-Alkoxy-(Ci-C6)-alkoxycarbonyl, (C2-C6)-Alkenyloxy-(Ci-C6)- alkoxycarbonyl, (Ci-C6)-Alkylamino-(CrC6)-alkoxycarbonyl, Tris[(Ci-C6)- alkyl]silyloxy-(Ci-C6)-alkoxycarbonyl, Bis[(Ci-C6)-Alkyl]amino-(Ci-C6)- alkoxycarbonyl, (Ci-C6)-Alkyl[(Ci-C6)-alkyl]amino-(Ci-C6)-alkoxycarbonyl, Cyano-(Ci-Co)-alkoxycarbonyl, Heterocyclyl-N-(Ci-C6)-alkoxycarbonyl, Bromine, iodine, (C 1 -C 6 ) -alkyl, (C 3 -C 6 ) -cycloalkyl, (C 2 -C 6 ) -alkenyl, (C 4 -C 6 ) -cycloalkenyl, (C 2 -C 6 ) Alkynyl, aryl (C 2 -C 6) alkynyl, tris [(C 1 -C 6 ) alkyl] silyl (C 2 -C 6 ) alkynyl, aryl, aryl (C 1 -C 6 ) alkyl, aryl - (Ci-C 6) alkoxy, heteroaryl, (Ci-Ce) - haloalkyl, (C3-C 6) halocycloalkyl, (C 2 -C 6) haloalkenyl, (Ci-C 6) alkoxy, (C -C 6) - haloalkoxy, aryloxy, heteroaryloxy, (C3-C6) cycloalkyloxy, (C3-C6) cycloalkyl (Ci-C 6) alkoxy, (C 2 -C 6) - (C 2 -C 6 ) Alkenyloxy, (C 2 -C 6 ) alkynyl (C 2 -C 6 ) alkyloxy, hydroxy (C 1 -C 6 ) alkyl, (C 1 -C 6 ) alkoxy (C 1 -C 6 ) alkyl , Aryloxy- (C 1 -C 6 ) -alkyl, heteroaryloxy- (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -alkylthio, (C 1 -C 6 ) -haloalkylthio, (C 1 -C 6 ) -alkoxycarbonyl- (C 1 -C 6 ) -alkyl ) -alkylthio, aryithio, (Cs-CeJ-cycloalkylthio, heteroaryithio, (C 1 -C 6 ) -alkylthio (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -alkylamino, bis [(C 1 -C 6 ) -alkyl] amino, (C 2 -C 6) -alkenylamino, (C 3 -C 6) -cycloalkylamino, (C 1 -C 6 -alkylcarbonylamino, (C 3 -C 6) -cycloalkylcarbonylamino, arylcarbonylamino, heter oarylcarbonylamino, formylamino, (C 1 -C 6) -haloalkylcarbonylamino, (C 1 -C 6) -alkoxycarbonylamino, (C 1 -C 6) -alkylaminocarbonylamino, (C 1 -C 6) -alkyl [(C 1 -C 6) -alkyl] aminocarbonylamino, (C 1 -C 6) ) Alkylsulfonylamino, (C 3 -C 6) -cycloalkylsulfonylamino, arylsulfonylamino, hetarylsulfonylamino, sulfonyl- (C 1 -C 6) -haloalkylamino, amino- (C 1 -C 6) -alkylsulfonyl, amino- (C 1 -C 6) -haloalkylsulfonyl, (C 1 -C 6 -alkylaminosulfonyl , Bis [(C 1 -C 6) -alkyl] aminosulfonyl, (C 3 -C 6) -cycloalkylaminosulfonyl, (C 1 -C 6) -haloalkylaminosulfonyl, Heteroarylaminosulfonyl, arylaminosulfonyl, aryl (Ci-C6) alkylaminosulfonyl, (Ci-C 6) alkylsulfonyl, (C 3 -C 6) -Cycioalkylsulfonyl, arylsulfonyl, (Ci-C6) - alkylsulphinyl, (C 3 -C 6 ) cycloalkylsulfinyl, arylsulfinyl, NS-bis [(dC 6) - alkyl] sulfonimidoyl, S- (Ci-Cc>) -Alkylsulfonimidoyl, (d-Ce) - alkylsulfonylaminocarbonyl, (C3-C6) -Cycloalkylsulfonylaminocarbonyl, aryl (CrCeJ alkylcarbonylamino, (C 3 -C 6) -cycloalkyl- (C 1 -C 6) -alkylcarbonylamino, heteroarylcarbonylamino, (C 1 -C 6) -alkoxy- (C 1 -C 6) -alkylcarbonylamino, hydroxy- (C 1 -C 6) -alkylcarbonylamino, (C 1 -C 6) alkoxycarbonylamino (Ci-C6) - alkylcarbonylamino, cyano, cyano (Ci-Ce) alkyl, hydroxycarbonyl, (Ci-Ce) - alkoxycarbonyl, (C3-Cr>) -cycloalkoxycarbonyl, (C3-Cr>) cycloalkyl - (Ci-C6) - alkoxycarbonyl, aryloxycarbonyl, aryl- (Ci-C6) -alkoxycarbonyl, (C2-Ce) - alkenyloxycarbonyl, (C2-Cr > ) -Alkinyloxycarbonyl, (Ci-CeJ-Haloalkyloxycarbonyl, (Ci-C 6 ) -Alkoxy- (C 1 -C 6 ) -alkoxycarbonyl, (C 2 -C 6 ) -alkenyloxy- (C 1 -C 6 ) -alkoxycarbonyl, (C 1 -C 6 ) -alkylamine o- (C 1 -C 6) alkoxycarbonyl, tris [(C 1 -C 6) alkyl] silyloxy- (C 1 -C 6) alkoxycarbonyl, bis [(C 1 -C 6) alkyl] amino- (C 1 -C 6) alkoxycarbonyl, (Ci -C 6) -alkyl [(C 1 -C 6) -alkyl] amino- (C 1 -C 6) -alkoxycarbonyl, cyano- (C 1 -C 6) -alkoxycarbonyl, heterocyclyl-N- (C 1 -C 6) -alkoxycarbonyl,
Heteroaryloxycarbonyl, Heteroaryl-(Ci-C6)-alkoxycarbonyl, Heterocyclyl-(Ci-C6)- alkoxycarbonyl, Heterocyclyloxycarbonyl, (C2-C6)-Alkenyl-(Ci-C6)- alkoxycarbonyl, (C2-Cö)-Alkinyl-(Ci-C6)-alkoxycarbonyl, Aryl-(C2-Ce)- alkinyloxycarbonyl, Aryl-(C2-C6)-alkenyloxycarbonyl, Aminocarbonyl, (d-Ce)- Alkylaminocarbonyl, Bis[(Ci-C6)-alkyl]aminocarbonyl, (Ci-C6)-Alkyl[(d-C6)- Alkyl]aminocarbonyl, (Ci-C6)-Alkyl[(CrC6)-Alkoxy]aminocarbonyl, (C2-Ce)- Alkenylaminocarbonyl, (Cs-CeJ-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C6)-alkylaminocarbonyl, Heteroaryl-(Ci-C6)-alkylaminocarbonyl, Cyano- (CrC6)-alkylaminocarbonyl, (CrCe Haloalkylaminocarbonyl, (C2-C6)-Alkinyl- (Ci-C6)-alkylaminocarbonyl, (Ci-Cö)-Alkoxycarbonylaminocarbonyl, Aryl-(Ci-Ce)- alkoxycarbonylaminocarbonyl, Hydroxycarbonyl-(Ci-C6)-alkyl, (Ci-Ce)- Alkoxycarbonyl-(Ci-Cö)-alkyl, (C3-C6)-Cycloalkoxycarbonyl-(Ci-C6)-alkyl, Heteroaryloxycarbonyl, heteroaryl- (C 1 -C 6) -alkoxycarbonyl, heterocyclyl- (C 1 -C 6) -alkoxycarbonyl, heterocyclyloxycarbonyl, (C 2 -C 6) -alkenyl- (C 1 -C 6) -alkoxycarbonyl, (C 2 -C 6) -alkynyl- (Ci -C6) alkoxycarbonyl, aryl- (C2-Ce) alkynyloxycarbonyl, aryl- (C2-C6) -alkenyloxycarbonyl, aminocarbonyl, (d-Ce) -alkylaminocarbonyl, bis [(Ci-C6) -alkyl] aminocarbonyl, (Ci -C6) alkyl [(d-C6) alkyl] aminocarbonyl, (Ci-C6) alkyl [(CrC6) alkoxy] aminocarbonyl, (C2-Ce) alkenylaminocarbonyl, (Cs-CeJ-cycloalkylaminocarbonyl, arylaminocarbonyl, aryl (C 1 -C 6) -alkylaminocarbonyl, heteroaryl- (C 1 -C 6) -alkylaminocarbonyl, cyano- (C 1 -C 6) -alkylaminocarbonyl, (C 1 -C 6 -alkylaminocarbonyl, (C 2 -C 6) -alkynyl- (C 1 -C 6) -alkylaminocarbonyl, C 6) alkoxycarbonylaminocarbonyl, aryl- (C 1 -C 6) -alkoxycarbonylaminocarbonyl, hydroxycarbonyl- (C 1 -C 6) -alkyl, (C 1 -C 6) -alkoxycarbonyl- (C 1 -C 6) -alkyl, (C 3 -C 6) -cycloalkoxycarbonyl- Ci-C6) alkyl,
(C3-C6)-Cycloalkyl-(Ci-C6)-alkoxycarbonyl-(Ci-C6)-alkyl, (C2-C6)- Alkenyloxycarbonyl-(CrC6)-alkyl, Aryl-(Ci-C6)-alkoxycarbonyl-(Ci-C6)-alkyl, (Ci-C6)-Alkylaminocarbonyi-(CrC6)-alkyl, Aminocarbonyl-(CrC6)-alkyl, (C3-C6) cycloalkyl (Ci-C 6) alkoxycarbonyl (Ci-C 6) alkyl, (C 2 -C 6) - alkenyloxycarbonyl (CRC6) alkyl, aryl (Ci-C6) - alkoxycarbonyl- (C 1 -C 6) -alkyl, (C 1 -C 6) -alkylaminocarbonyl (C 1 -C 6) -alkyl, aminocarbonyl- (C 1 -C 6) -alkyl,
Bis[(Ci-C6)-alkyl]aminocarbonyl-(Ci-C6)-alkyl, (C3-C6)-Cycloalkylaminocarbonyl- (Ci-C6)-alkyl, Aryl-(Ci-C6)-alkylaminocarbonyl-(Ci-C6)-alkyl, Heteroaryl-(Ci-C6)- alkylaminocarbonyl-(Ci-C6)-alkyl, Cyano-(Ci-C6)-alkylaminocarbonyl-(Ci-C6)- alkyl, (Ci-C6)-Haloalkylaminocarbonyi-(Ci-C6)-alkyl, (C2-C6)-Alkinyl-(Ci-C6)- alkylaminocarbonyl-(Ci-C6)-alkyl, (C3-C6)-Cycloalkyl-(Ci-C6)- alkylaminocarbonyl-(Ci-C6)-alkyl, (Ci-CeJ-Alkoxycarbonylaminocarbonyl- (Ci-Ce)-alkyl, Aryl-(Ci-C6)-alkoxycarbonylaminocarbonyl-(Ci-C6)-alkyl, (d-Ce)- Alkoxycarbonyl-(Ci-C6)-alkylaminocarbonyl, HydroxycarbonyKCrCe)- alkylaminocarbonyl, Aryl-(Ci-C6)-alkoxycarbonyl-(CrC6)-alkylaminocarbonyl, Aminocarbonyl-(Ci-C6)-alkylaminocarbonyl, (CrC6)-Alkylaminocarbonyl- (Ci-C6)-alkylaminocarbonyl. Bis [(C 1 -C 6 ) -alkyl] aminocarbonyl- (C 1 -C 6 ) -alkyl, (C 3 -C 6 ) -cycloalkylaminocarbonyl- (C 1 -C 6 ) -alkyl, aryl- (C 1 -C 6 ) -alkylaminocarbonyl- Ci-C 6) alkyl, heteroaryl (Ci-C 6) - alkylaminocarbonyl- (C 1 -C 6 ) -alkyl, cyano- (C 1 -C 6 ) -alkylaminocarbonyl- (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -haloalkylaminocarbonyl- (C 1 -C 6 ) -alkyl, (C 2 -C 6 ) -alkynyl- (C 1 -C 6 ) -alkylaminocarbonyl- (C 1 -C 6 ) -alkyl, (C 3 -C 6 ) -cycloalkyl- (C 1 -C 6 ) -alkylaminocarbonyl- (C 1 -C 6 ) -alkyl, (C 1 -C -J) Alkoxycarbonylaminocarbonyl- (C 1 -C 6) -alkyl, aryl- (C 1 -C 6) -alkoxycarbonylaminocarbonyl- (C 1 -C 6) -alkyl, (C 1 -C 6) -alkoxycarbonyl- (C 1 -C 6) -alkylaminocarbonyl, hydroxycarbonyKCrCe) -alkylaminocarbonyl, Aryl- (C 1 -C 6) alkoxycarbonyl- (C 1 -C 6) -alkylaminocarbonyl, aminocarbonyl- (C 1 -C 6) -alkylaminocarbonyl, (C 1 -C 6) -alkylaminocarbonyl- (C 1 -C 6) -alkylaminocarbonyl.
(C3-C6)-Cycloalkylaminocarbonyl-(Ci-C6)-alkylaminocarbonyl, (Ca-Ce)- Cycloalkyl-(CrC6)-alkylaminocarbonyl, (C3-C6)-Cycloalkyl-(Ci-C6)- alkylaminocarbonyl-(Ci-C6)-alkyl, (C3-C6)-Cycloalkyl-(Ci-C6)- alkylaminocarbonyl-(Ci-C6)-alkylaminocarbonyl, (C2-C6)-Alkenyl-(d-C6)- alkylaminocarbonyl, (C2-Cc>)-Alkenylaminocarbonyl-(Ci-C6)-alkyl, (C2-C6)- Alkenyl-(Ci-C6)-alkylaminocarbonyl-(Ci-C6)-alkyl, (d-CeJ-Alkylcarbonyl, (Ca-Ce)- Cycloalkylcarbonyl, Arylcarbonyl, Formyl, Hydroxyiminomethyl, (C3-C6) -cycloalkylaminocarbonyl- (Ci-C6) -alkylaminocarbonyl, (Ca-Ce) -cycloalkyl- (CrC6) -alkylaminocarbonyl, (C3-C6) -cycloalkyl- (Ci-C6) -alkylaminocarbonyl- (Ci-C 6 ) -alkyl, (C 3 -C 6 ) -cycloalkyl- (C 1 -C 6 ) -alkylaminocarbonyl- (C 1 -C 6 ) -alkylaminocarbonyl, (C 2 -C 6 ) -alkenyl- (C 1 -C 6 ) -alkylaminocarbonyl, (C 2 -C 6 -alkyl) cc>) -Alkenylaminocarbonyl- (Ci-C6) alkyl, (C2-C6) - alkenyl (Ci-C6) alkylaminocarbonyl (Ci-C6) alkyl, (d-CeJ-alkylcarbonyl, (Ca-Ce) Cycloalkylcarbonyl, arylcarbonyl, formyl, hydroxyiminomethyl,
Aminoiminomethyl, (Ci-C6)-Alkoxyiminomethyl, (Ci-C6)-A!kylaminoiminomethyl, Bis[(Ci-C6)-alkyl]aminoiminomethyl, (C3-Cö)-Cycloalkoxyiminomethyl, (C3-Ce)- Cycloalkyl-(Ci-C6)-alkoximinomethyl, Aryloximinomethyl, Aryl-(Ci-CG)- alkoxyiminomethyl, Aryl-(Ci-C6)-alkylaminoiminomethyi, (C2-C-6)- Alkenyloxyiminomethyl, Arylaminoiminomethyl, Arylsulfonylaminoiminomethyl, Heteroaryl-(Ci-C6)-alkyl, Heterocyclyl-(Ci-C6)-alkyl, Aminoiminomethyl, (C 1 -C 6) -alkoxyiminomethyl, (C 1 -C 6) -alkylaminoiminomethyl, bis [(C 1 -C 6) -alkyl] aminoiminomethyl, (C 3 -C 6) -cycloalkoxyiminomethyl, (C 3 -C 6) -cycloalkyl- (Ci -C6) -alkoximinomethyl, aryloximinomethyl, aryl- (Ci-CG) -alkoxyiminomethyl, aryl- (Ci-C6) -alkylaminoiminomethyl, (C2-C-6) -alkenyloxyiminomethyl, arylaminoiminomethyl, arylsulfonylaminoiminomethyl, heteroaryl- (Ci-C 6 ) -alkyl, heterocyclyl- (C 1 -C 6 ) -alkyl,
Hydroxycarbonylheterocyclyl, (CrC6)-Alkoxycarbonylheterocyclyl, (C2-Ce)- Alkenyloxycarbonylheterocyclyl, (C2-C6)-Alkenyl-(Ci-Cr,)- alkoxycarbonylheterocyclyl, Aryl-(Ci-Cc>)-alkoxycarbonylheterocyclyl, (Cs-Ce)- Cycloalkoxycarbonylheterocyclyl, (C3-C6)-Cycloalkyl-(CrC6)- a!koxycarbonylheterocyclyl, Aminocarbonylheterocyclyl, (Ci-Ce)- Alkylaminocarbonylheterocyclyl, Bis[(Ci-C6)-Alkyl]aminocarbonylheterocyclyl, (C3-C6)-Cycloalkylaminocarbonylheterocyclyl, Aryl-(Ci-Ce)- alkylaminocarbonylheterocyclyl, (C2-Cö)-Alkenylaminocarbonylheterocyclyl, Hydroxycarbonylheterocyclyl-(Ci-C6)-alkyl, (Ci-C6)-Alkoxycarbonylheterocyclyl- (CrC6)-alkyl, Hydroxycarbonyl-(C3-C6)-cycloalkyl-(Ci-C6)-alkyl, (CrC6)- Alkoxycarbonyl-(C3-C6)-cycloalkyl-(CrC6)-alkyl, Hydroxyaminocarbonyl, (Ci-C6)-Alkoxyaminocarbonyl, Aryl-(Ci-C6)-alkoxyaminocarbonyl, Heterocyclyl, (Ci-C-6)-Alkylcarbonyloxy, Arylcarbonyloxy, Heteroarylcarbonyloxy, (Ca-Ce)- Cycloalkylcarbonyloxy, (Ci-C6)-Alkoxycarbonyloxy, (C2-Ce)- Alkenyloxycarbonyloxy, Aminosulfonyl, (Ci-C6)-Alkoxycarbonyl-heterocyclyl-N- carbonyl, (Ci-C6)-Alkoxycarbonyl-(Ci-C6)-alkyl-heterocyclylidenaminocarbonyl, (Ci-C6)-Alkoxycarbonylheterocyclyliden-(CrC6)-alkylaminocarbonyl, (d-Ce)- Alkoxycarbonyl-(Ci-C6)-Alkyl((Ci-C6)-aikyl)aminocarbonyl, (d-Ce)- Alkoxycarbonyl-(C3-C6)-cycloalkylidenaminocarbonyl, Heterocyclyl-N-carbonyl, (Ci-C6)-Alkoxy-(Ci-C6)-alkylaminocarbonyi steht, Hydroxycarbonylheterocyclyl, (CRC6) -Alkoxycarbonylheterocyclyl, (C2-Ce) - Alkenyloxycarbonylheterocyclyl, (C2-C6) alkenyl (C Cr) - alkoxycarbonylheterocyclyl, aryl (Ci-Cc>) -alkoxycarbonylheterocyclyl, (Cs-Ce) - Cycloalkoxycarbonylheterocyclyl, (C3-C6) -cycloalkyl- (CrC6) -alkoxycarbonylheterocyclyl, aminocarbonylheterocyclyl, (Ci-Ce) -alkylaminocarbonylheterocyclyl, bis [(Ci-C6) -alkyl] aminocarbonylheterocyclyl, (C3-C6) -cycloalkylaminocarbonylheterocyclyl, aryl- (C 1 -C 6 ) -alkylaminocarbonylheterocyclyl, (C 2 -C 6 ) -alkenylaminocarbonylheterocyclyl, hydroxycarbonylheterocyclyl- (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -alkoxycarbonylheterocyclyl- (C 1 -C 6 ) -alkyl, hydroxycarbonyl- (C 3 -C 6 ) -cycloalkyl - (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -alkoxycarbonyl- (C 3 -C 6 ) -cycloalkyl- (C 1 -C 6 ) -alkyl, hydroxyaminocarbonyl, (C 1 -C 6 ) -alkoxyaminocarbonyl, aryl- (C 1 -C 6 ) -alkoxyaminocarbonyl , Heterocyclyl, (C 1 -C 6) -alkylcarbonyloxy, arylcarbonyloxy, heteroarylcarbonyloxy, (C 1 -C 6) -cycloalkylcarbonyloxy, (C 1 -C 6) -alkoxycarbonyloxy, (C 2 -C 6) -alkenyloxycarbonyloxy, aminosulfonyl, (C 1 -C 6) -alkoxycarbonyl-heterocyclyl- N-carbonyl, (C 1 -C 6) -alkoxycarbonyl- (C 1 -C 6) -alkyl-heterocyclylideneaminocarbonyl, (C 1 -C 6) -alkoxycarbonylheterocyclylidene (C 1 -C 6) -alkylaminocarbonyl, (C 1 -C 6) -alkoxycarbonyl- (C 1 -C 6) - Alkyl ((Ci-C6) -aikyl) aminocarbonyl, (d-Ce) - alkoxycarbonyl (C3-C6) -cycloalkylidenaminocarbonyl, heterocyclyl-N-carbonyl, (Ci-C6) -alkoxy- (Ci-C6) -alkylaminocarbonyi .
R7, R8, R9, R10, R11 und R12 unabhängig voneinander für Wasserstoff, (Ci-C6)-Alkyl, (C3-C6)-Cycloalkyl, (C2-C6)-Alkenyl, (C2-C6)-Alkenyl-(Ci-C6)-alkyl, (d-C6)- Alkoxy-(Ci-C6)-alkyl, Hydroxy-(Ci-C6)-alkyl, (CrC6)-Haioalkyl, (C2-C6)- Haioaikenyl, (Ci-C6)-Haloalkoxy-(Ci-C6)-alkyl. (Ci-C7)-Alkoxy, (CrC7)-Alkylthio, (CrC7)-Alkylamino, Halogen, Amino stehen, wobei mindestens eine der Gruppen R7, R8, R9, R10, R11 und R 2 nicht für Wasserstoff steht und R 7, R 8, R 9, R 10, R 11 and R 12 are independently hydrogen, (Ci-C 6) -alkyl, (C 3 -C 6) -cycloalkyl, (C 2 -C 6) alkenyl , (C2-C6) alkenyl (Ci-C 6) alkyl, (dC 6) - alkoxy- (Ci-C 6) alkyl, hydroxy (Ci-C 6) alkyl, (CrC 6) -Haioalkyl, (C 2 -C 6 ) - Haioaikenyl, (Ci-C 6 ) -haloalkoxy- (Ci-C6) -alkyl. (Ci-C7) alkoxy, (CrC 7) alkylthio, (CrC 7) -alkylamino, halogen, amino, with at least one of the groups R 7, R 8, R 9, R 10, R 11 and R 2 does not stand for hydrogen and
R3 und R4 mit dem Atom, an das sie gebunden sind, eine exo-Alkylidengruppe oder einen vollständig gesättigten, gegebenenfalls durch O (Sauerstoff), S R 3 and R 4 with the atom to which they are attached, an exo-alkylidene group or a fully saturated, optionally substituted by O (oxygen), S
(Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und (Sulfur) or a group NH, NR 37 interrupted and
gegebenenfalls weiter substituierten 3 bis 6-gliedrigen Ring bilden,  optionally form further substituted 3 to 6-membered ring,
R1 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 1 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
R1 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, R 1 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
R3 und R7 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H , N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 3 and R 7 with the atoms to which they are attached, a fully saturated or partially saturated, optionally by O (oxygen), S (sulfur) or form a group NH, NR 37 interrupted and optionally further substituted 5 to 7-membered ring,
R3 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, R 3 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
R1 und R3 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 1 and R 3 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
R7 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 7 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
R3 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, R 3 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
R7 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, R 7 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
R13, R14, R15 und R16 unabhängig voneinander für Wasserstoff, Fluor, Chlor, Brom, lod, Nitro, Amino, Cyano, (Ci-Ce)-Alkyl, gegebenenfalls substituiertes Phenyl, Heteroaryl, (C3-C6)-Cycloalkyl, (C4-C6)-Cycloalkenyl, (C2-C6)-Alkenyl, (C2-C6)- Alkinyl, (C2-C6)-Alkenyl-(Ci-C6)-alkyl, (C2-C6)-Alkinyl-(Ci-C6)-alkyl, Hydroxy, (Ci-C6)-Alkoxy, (Ci-C6)-Alkoxy-(Ci-C6)-alkoxy, (Ci-C6)-Alkoxy-(Ci-C6)-alkyl, Hydroxy-(Ci-C6)-alkyl, (CrC6)-Haloalkoxy, (Ci-C6)-Haloalkyl, (C2-C6)- Haloalkenyl, (C2-C6)-Haloalkinyl, (Ci-C6)-Haloalkoxy-(Ci-C6)-alkyl, (Ci-Ce)- Alkoxy-(Ci-C6)-haloalkyl, (Ci-C6)-Haloalkoxy-(Ci-C6)-haloalkyl, Hydrothio, (Ci-C6)-Alkylthio, (Ci-C6)-Haloalkylthio, (Ci-C6)-Alkylthio-(Ci-C6)-alkyl, (Ci-C6)- Haloalkylthio-(Ci-C6)-alkyl, (Ci-C6)-Alkylamino, Bis-[(Ci-C6)-alkyl]amino, (C2-C6)-Alkenylamino, (Cs-Ce Cycloalkylamino, (Ci-C6)-Alkylcarbonylamino, (Ca-Cr-Cycloalkylcarbonylamino, Arylcarbonyiamino, Heteroarylcarbonylamino, Formylamino, (Ci-C6)-Haloalkylcarbonylamino, (d-CeJ-Alkoxycarbonylamino, (Ci-C6)-Alkylaminocarbonylamino, (d-Ce)- Alkyl[(Ci-Ce)- Alkyl]aminocarbonylamino, (Ci-Cc>)-Alkylsulfonylamino, (C3-Ce)- Cycloalkylsulfonylamino, Arylsulfonylamino, Hetarylsulfonylamino, Sulfonyl- (CrC6)-haloalkylamino, Amino-(CrC6)-alkylsulfonyl, Amino-(Ci-Ce)- haloalkylsulfonyl, (Ci-CeJ-Alkylaminosulfonyl, Bis[(Ci-C6)-alkyl]aminosulfonyl, (C3-C6)-Cycloalkylaminosulfonyl, (Ci-C6)-Haloalkylaminosulfonyl, R 13, R 14, R 15 and R 16 independently of one another represent hydrogen, fluorine, chlorine, bromine, iodine, nitro, amino, cyano, (Ci-Ce) alkyl, optionally substituted phenyl, heteroaryl, (C 3 -C 6 ) cycloalkyl, (C 4 -C 6) -cycloalkenyl, (C 2 -C 6) alkenyl, (C 2 -C 6) - alkynyl, (C2-C6) alkenyl (Ci-C 6) - alkyl, (C 2 -C 6 ) -alkynyl- (C 1 -C 6 ) -alkyl, hydroxyl, (C 1 -C 6 ) -alkoxy, (C 1 -C 6 ) -alkoxy- (C 1 -C 6 ) -alkoxy, ( Ci-C 6) alkoxy (Ci-C6) alkyl, hydroxy (Ci-C 6) alkyl, (CrC 6) haloalkoxy, (Ci-C 6) -haloalkyl, (C 2 -C 6) - Haloalkenyl, (C2-C6) haloalkynyl, (Ci-C6) haloalkoxy (Ci-C 6) alkyl, (Ci-Ce) - alkoxy- (Ci-C 6) -haloalkyl, (Ci-C 6 ) Haloalkoxy- (C 1 -C 6 ) -haloalkyl, hydrothio, (C 1 -C 6 ) -alkylthio, (C 1 -C 6 ) -haloalkylthio, (C 1 -C 6 ) -alkylthio (C 1 -C 6 ) -alkyl , (C 1 -C 6 ) -haloalkylthio (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -alkylamino, bis [(C 1 -C 6 ) -alkyl] -amino, (C 2 -C 6 ) -alkenylamino, (C 1 -C 6 -cycloalkylamino, (C 1 -C 6) -alkylcarbonylamino, (C 1 -C 6 -cycloalkylcarbonylamino, arylcarbonyiamino, heteroarylcarbonylamino, formylamino, (C 1 -C 6) -haloalkylcarbonylamino, (d-CeJ-alkoxycarbonylamino, (C 1 -C 6) -alkylaminocarbonylamino, (d-Ce) - alkyl [(Ci-Ce) -alkyl] aminocarbonylamino, (Ci-Cc>) - alkylsulfonylamino, (C3-Ce) - cycloalkylsulfonylamino, arylsulfonylamino, hetarylsulfonylamino, sulfonyl (CrC6) -haloalkylamino, amino ( C 1 -C 6) -alkylsulfonyl, amino- (C 1 -C 6) -haloalkylsulfonyl, (C 1 -C 6 -alkylaminosulfonyl, bis [(C 1 -C 6) -alkyl] aminosulfonyl, (C 3 -C 6) -cycloalkylaminosulfonyl, (C 1 -C 6) -haloalkylaminosulfonyl,
Heteroarylaminosulfonyl, Arylaminosulfonyl, Aryl-(CrC6)-alkylaminosulfonyl, (Ci-Cc>)-Alkylsulfonyl, (Ca-CeJ-Cycloalkylsulfonyl, Arylsulfonyl, Hydroxycarbonyi, (Ci-C6)-Alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl- (d-Cr-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(d-C6)-alkoxycarbonyl, (C2-Ce)- Alkenyloxycarbonyl, (C2-C6)-Alkinyloxycarbonyl, Aminocarbonyl, (Ci-Ce)- Alkylaminocarbonyl, Bis[(Ci-C6)-alkyl]aminocarbonyl, (Ci-C6)-Alkyl[(Ci-Cf,)- Alkyljaminocarbonyl, (Ci-C6)-Alkyl-[(Ci-C6)-Alkoxy]aminocarbonyl, (C2-Ce)- Alkenylaminocarbonyl, (Ca-Ce Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C6)-alkylaminocarbonyl stehen, Heteroarylaminosulfonyl, arylaminosulfonyl, aryl (CRC6) alkylaminosulfonyl, (Ci-Cc>) alkylsulfonyl, (Ca-CeJ-cycloalkylsulfonyl, arylsulfonyl, Hydroxycarbonyi, (Ci-C6) alkoxycarbonyl, (C3-C6) cycloalkoxycarbonyl, (C3 -C6) -cycloalkyl- (d-Cr-alkoxycarbonyl, aryloxycarbonyl, aryl- (d-C6) -alkoxycarbonyl, (C2-Ce) -alkenyloxycarbonyl, (C2-C6) -alkynyloxycarbonyl, aminocarbonyl, (Ci-Ce) -alkylaminocarbonyl , Bis [(Ci-C6) alkyl] aminocarbonyl, (Ci-C6) alkyl [(Ci-Cf,) - alkyljaminocarbonyl, (Ci-C6) alkyl - [(Ci-C6) alkoxy] aminocarbonyl, ( C 2 -C 6) - alkenylaminocarbonyl, (C 1 -C 6 -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 6) -alkylaminocarbonyl,
A1, A2, A3 und A4 gleich oder verschieden sind und unabhängig voneinander für NA 1 , A 2 , A 3 and A 4 are the same or different and are independently N
(Stickstoff) oder die Gruppierungen C-H, C-CH3, C-F, C-Cl, C-Br, C-l, C-OCF3, C-OCH3, C-CF3, C-CO2H, C-CO2CH3 stehen, wobei jedoch in keinem Fall mehr als zwei N-Atome benachbart sind, (Nitrogen) or the groupings CH, C-CH 3, CF, C-Cl, C-Br, CI, C-OCF3, C-OCH3, C-CF 3, C-CO2H, C-CO2CH3 are, but using in no case are more than two N atoms adjacent,
R17 und R18 unabhängig voneinander für Wasserstoff, Halogen, (Ci-C6)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (C3-C6)-Cycloalkyl, (C2-C6)-Alkenyl, (C2-C6)-Alkinyl, (Ci-Ce)-Alkoxy, (Ci-C6)-Alkoxy-(Ci-C6)-alkyl, Aryloxy-(Ci-C6)-alkyl, (CrC6)- Haloalkoxy, (CrC6)-Haloalkyl, (Ci-C6)-Haloalkoxy-(Ci-C6)-alkyl, (Ci-C6)-Alkoxy- (Ci-C6)-haloalkyl, (Ci-C6)-Haloalkoxy-(Ci-C6)-haloalkyl, (Ci-C6)-Alkylthio, R 17 and R 18 independently of one another represent hydrogen, halogen, (C 1 -C 6 ) -alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 6 ) -cycloalkyl, (C 2 -C 6 ) -alkenyl, (C 2 -) C 6 ) -alkynyl, (C 1 -C 6 ) -alkoxy, (C 1 -C 6 ) -alkoxy- (C 1 -C 6 ) -alkyl, aryloxy- (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -haloalkoxy, ( C 1 -C 6 ) -haloalkyl, (C 1 -C 6 ) -haloalkoxy- (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -alkoxy- (C 1 -C 6 ) -haloalkyl, (C 1 -C 6 ) -haloalkoxy (C 1 -C 6 ) -haloalkyl, (C 1 -C 6 ) -alkylthio,
(Ci-Ce)-Haloalkylthio, (Ci-C6)-Alkylthio-(Ci-C6)-alkyl, Hydroxycarbonyi, (Ci-C6)- Alkoxycarbonyl, (C3-Ce)-Cycloalkoxycarbonyl, (C3-Ce)-Cycloalkyl-(Ci-C6)- alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C6)-alkoxycarbonyl, (C2-Ce)- Alkenyloxycarbonyl, (C2-C6)-Alkinyloxycarbonyl, Aminocarbonyl, (Ci-Ce)- Alkylaminocarbonyl, Bis[(Ci-C6)-alkyl]aminocarbonyl, (Ci-C6)-Alkyl[(d-C6)- Alkyl]aminocarbonyl, (Ci-C6)-Alkyl[(Ci-C6)-Alkoxy]aminocarbonyl, (C2-Ce)- Alkenylaminocarbonyl, (C3-C6)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(CrC6)-alkylaminocarbonyl stehen, (Ci-Ce) haloalkylthio, (Ci-C 6) alkylthio (Ci-C 6) alkyl, Hydroxycarbonyi, (Ci-C 6) - Alkoxycarbonyl, (C3-Ce) -cycloalkoxycarbonyl, (C3-Ce) -cycloalkyl- (Ci-C6) -alkoxycarbonyl, aryloxycarbonyl, aryl- (Ci-C6) -alkoxycarbonyl, (C2-Ce) -alkenyloxycarbonyl, (C2-C6 ) -Alkynyloxycarbonyl, aminocarbonyl, (C 1 -C 6) -alkylaminocarbonyl, bis [(C 1 -C 6) -alkyl] aminocarbonyl, (C 1 -C 6) -alkyl [(C 1 -C 6) -alkyl] aminocarbonyl, (C 1 -C 6) - Alkyl [(C 1 -C 6) -alkoxy] aminocarbonyl, (C 2 -C 6) -alkenylaminocarbonyl, (C 3 -C 6) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 6) -alkylaminocarbonyl,
A5 für S (Schwefel), O (Sauerstoff) oder die Gruppierungen N-H, N-CH3, N-CH2CH3, N- CH(CH3)2, N-C02t-Bu, N-Aryl, N-Heteroaryl, N-Heterocyclyl steht, A 5 for S (sulfur), O (oxygen) or the groupings NH, N-CH 3 , N-CH 2 CH 3 , N-CH (CH 3 ) 2 , N-CO 2 t-Bu, N-aryl, N-heteroaryl , N-heterocyclyl,
R19, R20, R23 und R24 unabhängig voneinander für Wasserstoff, (Ci-Ce)-Alkyl, Halogen, (C3-C6)-Cycloalkyl, Aryl, Heteroaryl, Heterocyclyl, (C2-C6)-Alkenyl, (C2-C6)- Alkenyl-(CrC6)-alkyl, Aryl-(Ci-C6)-alkyl, (Ci-Ce)-Alkoxy, (Ci-C6)-Alkoxy-(Ci-C6)- alkoxy, (Ci-C6)-Alkoxy-(Ci-C6)-alkyl, Hydroxy, (CrC6)-Haloalkyl, (d-C6)- Haloalkylthio stehen, R 19 , R 20 , R 23 and R 24 independently of one another represent hydrogen, (C 1 -C 6 ) -alkyl, halogen, (C 3 -C 6 ) -cycloalkyl, aryl, heteroaryl, heterocyclyl, (C 2 -C 6 ) - alkenyl, (C 2 -C 6) - alkenyl, (CrC 6) alkyl, aryl (Ci-C 6) alkyl, (Ci-Ce) alkoxy, (Ci-C 6) alkoxy (Ci- C 6) - alkoxy, (Ci-C6) alkoxy (Ci-C 6) alkyl, hydroxy, (CrC 6) -haloalkyl, (dC 6) - haloalkylthio stand,
R19 und R23 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 19 and R 23 with the atoms to which they are attached form a completely saturated or partially saturated, optionally further substituted 5 to 7-membered ring,
A6, A7 gleich oder verschieden sind und unabhängig voneinander für O (Sauerstoff), S (Schwefel), N-H, N-OCH3, N-CH3 oder die Gruppierung CR21 R22 stehen, wobei jedoch in keinem Fall zwei N-, O- oder S-Atome benachbart sind, und wobei R21 und R22 in der Gruppierung CR21 R22 jeweils gleiche oder verschiedene A 6 , A 7 are identical or different and independently of one another represent O (oxygen), S (sulfur), NH, N-OCH 3, N-CH 3 or the group CR 21 R 22 , but in no case are two N , O or S atoms are adjacent, and wherein R 21 and R 22 in the group CR 21 R 22 are each the same or different
Bedeutungen gemäß der nachstehenden Definition haben und  Have meanings as defined below and
R21 und R22 unabhängig voneinander für Wasserstoff, Fluor, Chlor, Brom, lod, (Ci-Ce)- Alkyl, Aryl, Heteroaryl, Heterocyclyl, (C3-C6)-Cycloalkyl, (C2-Ce)-Alkenyl, R 21 and R 22 independently of one another represent hydrogen, fluorine, chlorine, bromine, iodine, (C 1 -C 6) -alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 6) -cycloalkyl, (C 2 -C 6) -alkenyl,
(Ci-C6)-Alkoxy, (Ci-C6)-Alkoxy-(Ci-C6)-alkyl, Aryloxy-(Ci-C6)-alkyl, (CrC6)- Haloalkoxy, (Ci-Ce)-Haloalkyl, (Ci-C6)-Haloalkoxy-(Ci-C6)-alkyl, (Ci-Ce)-Alkoxy- (CrC6)-haloalkyl, (Ci-C6)-Haloalkoxy-(Ci-C6)-haloalkyl, (Ci-C6)-Alkylthio, (C 1 -C 6 ) -alkoxy, (C 1 -C 6 ) -alkoxy- (C 1 -C 6 ) -alkyl, aryloxy- (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -haloalkoxy, (C 1 -C 6 ) haloalkyl, (Ci-C 6) haloalkoxy (Ci-C 6) alkyl, (Ci-Ce) alkoxy (CrC 6) -haloalkyl, (Ci-C 6) haloalkoxy (Ci-C 6 ) -haloalkyl, (C 1 -C 6 ) -alkylthio,
(Ci-Ce)-Haloalkylthio, (Ci-C6)-Alkylthio-(Ci-C6)-alkyl, Hydroxycarbonyl, (d-C6)- Alkoxycarbonyl, (C3-Ce)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci-C6)- alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C-6)-alkoxycarbonyl, (Cz-Ce)- Alkenyloxycarbonyl, (C2-Co)-Alkinyloxycarbonyl, Aminocarbonyl, (d-Ce)- Alkylaminocarbonyl, Bis[(Ci-C6)-alkyl]aminocarbonyl, (Ci-C6)-Alkyl[(Ci-Cc,)- Alkyljaminocarbonyl, (Ci-C6)-Alkyl[(Ci-C6)-Alkoxy]aminocarbonyl, (C2-Ce)- Alkenylaminocarbonyl, (C3-Cö)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C6)-alkylaminocarbonyL Amino, (Ci-CeJ-Alkylamino, (Ca-Ce)- Cycloalkylamino, Bis-[(Ci-C6)-Alkyl]amino stehen, (C 1 -C 6 ) -haloalkylthio, (C 1 -C 6 ) -alkylthio (C 1 -C 6 ) -alkyl, hydroxycarbonyl, (C 1 -C 6 ) -alkoxycarbonyl, (C 3 -C 6 ) -cycloalkoxycarbonyl, (C 3 -C 6) - cycloalkyl- (Ci-C6) - alkoxycarbonyl, aryloxycarbonyl, aryl- (Ci-C-6) -alkoxycarbonyl, (Cz-Ce) -alkenyloxycarbonyl, (C2-Co) -alkynyloxycarbonyl, aminocarbonyl, (d-Ce) -alkylaminocarbonyl, bis [(Ci-C6) - alkyl] aminocarbonyl, (C 1 -C 6) -alkyl [(C 1 -C 4 -alkyl) aminocarbonyl, (C 1 -C 6) -alkyl [(C 1 -C 6) -alkoxy] aminocarbonyl, (C 2 -C 6) -alkenylaminocarbonyl, (C 3 -C 4) C 6) cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 6) -alkylaminocarbonyL amino, (C 1 -C 6 -alkylamino, (C 1 -C 6) -cycloalkylamino, bis [(C 1 -C 6) -alkyl] -amino,
R25, R26, R28 und R29 unabhängig voneinander für Wasserstoff, (Ci-Ce)-Alkyl, Halogen, (C3-C6)-Cycloalkyl, Aryl, Heteroaryl, Heterocyclyl, (C2-C6)-Alkenyl, Aryl-(Ci-Ce)- alkyl, (Ci-Ce)-Alkoxy, (Ci-C6)-Alkoxy-(Ci-C6)-alkoxy, (Ci-C6)-Alkoxy-(Ci-C6)- alkyl, (Ci-Ce)-Haloalkyl stehen, R 25 , R 26 , R 28 and R 29 independently of one another represent hydrogen, (C 1 -C 6 ) -alkyl, halogen, (C 3 -C 6 ) -cycloalkyl, aryl, heteroaryl, heterocyclyl, (C 2 -C 6 ) - alkenyl, aryl (Ci-Ce) - alkyl, (Ci-Ce) alkoxy, (Ci-C6) alkoxy (Ci-C 6) alkoxy, (Ci-C 6) alkoxy (Ci- C 6 ) -alkyl, (C 1 -C 6 ) -haloalkyl,
A8 für O (Sauerstoff), S (Schwefel), N-H, N-CH3, N-OCH3 oder die Gruppierung CHR27 steht und wobei R27 in der Gruppierung CHR27 die Bedeutung gemäß der nachstehenden Definition hat, A 8 is O (oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the moiety CHR 27 , and wherein R 27 in the moiety CHR 27 has the meaning as defined below,
R27 für Wasserstoff, Halogen, (Ci-CeJ-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (C3-Ce)- Cycloalkyl, (C2-C6)-Alkenyl, (Ci-C6)-Alkoxy, (Ci-C6)-Alkoxy-(Ci-C6)-alkyl, Aryloxy-(Ci-C6)-alkyl, (Ci-C6)-Haloalkoxy, (Ci-C6)-Haloalkyl. (Ci-C6)-Alkoxy- (Ci-C6)-haloalkyl, (Ci-C6)-Haloalkoxy-(Ci-C6)-haloalkyl, (Ci-C6)-Alkylthio, R 27 is hydrogen, halogen, (Ci-CeJ-alkyl, aryl, heteroaryl, heterocyclyl, (C3-Ce) - cycloalkyl, (C 2 -C 6) alkenyl, (Ci-C 6) alkoxy, (Ci- C 6 ) -alkoxy- (C 1 -C 6 ) -alkyl, aryloxy- (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -haloalkoxy, (C 1 -C 6 ) -haloalkyl. (C 1 -C 6 ) Alkoxy- (C 1 -C 6 ) -haloalkyl, (C 1 -C 6 ) -haloalkoxy- (C 1 -C 6 ) -haloalkyl, (C 1 -C 6 ) -alkylthio,
(Ci-C6)-Haloalkylthio, (Ci-C6)-Alkylthio-(Ci-C6)-alkyl, Hydroxycarbonyl, (CrC6)- Alkoxycarbonyl, (Ca-CeJ-Cycloalkoxycarbonyl, Aryl-(Ci-C6)-alkoxycarbonyl, (C2-C6)-Alkenyloxycarbonyl, (C2-C6)-Alkinyloxycarbonyl, Aminocarbonyl, (C 1 -C 6 ) -haloalkylthio, (C 1 -C 6 ) -alkylthio (C 1 -C 6 ) -alkyl, hydroxycarbonyl, (C 1 -C 6 ) -alkoxycarbonyl, (C 1 -C 12 -cycloalkoxycarbonyl, aryl- (C 1 -C 6 ) alkoxycarbonyl, (C 2 -C 6) -alkenyloxycarbonyl, (C 2 -C 6) -alkynyloxycarbonyl, aminocarbonyl,
(CrC6)-Alkylaminocarbonyl, Bis[(Ci-C6)-alkyl]aminocarbonyl, (d-Ce)- Alkyl[(CrC6)-Alkyl]aminocarbonyl, (Ci-C6)-Alkyl[(Ci-C6)-Alkoxy]aminocarbonyl, (C2-C6)-Alkenylaminocarbonyl, (C3-C6)-Cycloalkylaminocarbonyl,  (C 1 -C 6) -alkylaminocarbonyl, bis [(C 1 -C 6) -alkyl] aminocarbonyl, (C 1 -C 6) -alkyl [(C 1 -C 6) -alkyl] aminocarbonyl, (C 1 -C 6) -alkyl [(C 1 -C 6) -alkoxy] aminocarbonyl, (C 2 -C 6) -alkenylaminocarbonyl, (C 3 -C 6) -cycloalkylaminocarbonyl,
Arylaminocarbonyl, Aryl-(Ci-C6)-alkylaminocarbonyl, Amino, (Ci-C6)-Alkylamino, (Ca-CeJ-Cycloalkylamino, Bis-[(Ci-C6)-Alkyl]amino steht,  Arylaminocarbonyl, aryl- (C 1 -C 6) -alkylaminocarbonyl, amino, (C 1 -C 6) -alkylamino, (C 1 -C 12 -cycloalkylamino, bis - [(C 1 -C 6) -alkyl] -amino,
R30, R31, R32, R34, R35 und R36 unabhängig voneinander für Wasserstoff. (Ci-C6)-Alkyl, Halogen, (Ca-CeJ-Cycloalkyl, Aryl, Heteroaryl, Heterocyclyl, (C2-C6)-Alkenyl, (Ci-C6)-Alkoxy, (Ci-C6)-Alkoxy-(Ci-C6)-alkoxy, (Ci-C6)-Alkoxy-(Ci-C6)-alkyl, (Ci-C6)-Haloalkyl, (Ci-C6)-Alkylthio, (Ci-C6)-Haloalkylthio stehen, A9 für O (Sauerstoff), S (Schwefel), N-H, N-CH3, N-OCH3 oder die Gruppierung CHR33 steht und wobei R33 in der Gruppierung CHR33 die Bedeutung gemäß der nachstehenden Definition hat und R 30 , R 31 , R 32 , R 34 , R 35 and R 36 are each independently hydrogen. (C 1 -C 6 ) -alkyl, halogen, (C 1 -C 6 -cycloalkyl, aryl, heteroaryl, heterocyclyl, (C 2 -C 6 ) -alkenyl, (C 1 -C 6 ) -alkoxy, (C 1 -C 6 ) -alkoxy) (Ci-C 6) alkoxy, (Ci-C6) alkoxy (Ci-C 6) alkyl, (Ci-C 6) -haloalkyl, (Ci-C 6) alkylthio, (Ci-C 6 ) Haloalkylthio, A 9 is O (oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the group CHR 33 and wherein R 33 in the group CHR 33 has the meaning as defined below and
R33 für Wasserstoff, Halogen, (Ci-Ce)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (Ca-Ce)- Cycloalkyl, (C2-C6)-Alkenyl, (Ci-Ce)-Alkoxy, (Ci-C6)-Alkoxy-(Ci-C6)-alkyl, Aryloxy-(Ci-C6)-alkyl, (Ci-C6)-Haloalkoxy, (Ci-C6)-Haloalkyl, (Ci-Ce)-Alkylthio, (Ci-C6)-Haloalkylthio, Hydroxycarbonyl, (Ci-C6)-Alkoxycarbonyl, (Ca-Ce)- Cycloalkoxycarbonyl, Aryl-(Ci-C6)-alkoxycarbonyl, (C2-Ce)-Alkenyloxycarbonyl, (C2-C6)-Alkinyloxycarbonyl, Aminocarbonyl, (Ci-CeJ-Alkylaminocarbonyl, Bis[(Ci-C6)-alkyl]aminocarbonyl, (CrC6)-Alkyl[(Ci-C6)-Alkyl]aminocarbonyl, (d-C6)-Alkyl[(Ci-C6)-Alkoxy]aminocarbonyl, (C2-C6)-Alkenylaminocarbonyl, (C3-C6)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-Ce)- alkylaminocarbonyl, Amino, (Ci-C6)-Alkylamino, (C3-C6)-Cycloalkylamino, Bis- [(CrC6)-Alkyl]amino steht, R 33 is hydrogen, halogen, (C 1 -C 6 ) -alkyl, aryl, heteroaryl, heterocyclyl, (C 1 -C 6 ) -cycloalkyl, (C 2 -C 6 ) -alkenyl, (C 1 -C 6 ) -alkoxy, ( C 6 ) -alkoxy- (C 1 -C 6 ) -alkyl, aryloxy- (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -haloalkoxy, (C 1 -C 6 ) -haloalkyl, (C 1 -C 4) - Alkylthio, (C 1 -C 6) -haloalkylthio, hydroxycarbonyl, (C 1 -C 6) -alkoxycarbonyl, (C 1 -C 6) -cycloalkoxycarbonyl, aryl- (C 1 -C 6) -alkoxycarbonyl, (C 2 -C 6) -alkenyloxycarbonyl, (C 2 -C 6) ) -Alkynyloxycarbonyl, aminocarbonyl, (C 1 -C 6 -alkylaminocarbonyl, bis [(C 1 -C 6) -alkyl] aminocarbonyl, (C 1 -C 6) -alkyl [(C 1 -C 6) -alkyl] aminocarbonyl, (C 1 -C 6) -alkyl [( C 1 -C 6) -alkoxy] aminocarbonyl, (C 2 -C 6) -alkenylaminocarbonyl, (C 3 -C 6) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 6) -alkylaminocarbonyl, amino, (C 1 -C 6) -alkylamino, (C 3 -C 6) -cycloalkylamino, bis- [(C 1 -C 6 ) -alkyl] -amino,
R37 für (Ci-C6)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (C3-C6)-Cycloalkyl, (C2-C6)-Alkenyl, (Ci-C6)-Alkoxy, (Ci-C6)-Alkoxy-(Ci-C6)-alkyl, Aryloxy-(Ci-Cr>)-alkyl, (Ci-C6)- Alkoxycarbonyl, (C3-C6)- Cycloalkoxycarbonyl, Aryl-(Ci-C6)-alkoxycarbonyl, (C2-C6)-Alkenyloxycarbonyl, (C2-C6)-Alkinyloxycarbonyl, (d-Cö)-Alkylcarbonyl, (C3-Cr,)-Cycloalkylcarbonyl, Arylcarbonyl, Heteroarylcarbonyl steht. R 37 is (Ci-C 6) alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 6) -cycloalkyl, (C 2 -C 6) alkenyl, (Ci-C 6) alkoxy, (Ci- C 6) alkoxy- (Ci-C 6) alkyl, aryloxy (Ci-Cr>) alkyl, (Ci-C6) - alkoxycarbonyl, (C3-C6) - cycloalkoxycarbonyl, aryl (Ci-C6) alkoxycarbonyl, (C 2 -C 6) alkenyloxycarbonyl, (C 2 -C 6) alkynyloxycarbonyl, (C 1 -C 6) alkylcarbonyl, (C 3 -C 18) cycloalkylcarbonyl, arylcarbonyl, heteroarylcarbonyl.
Im Speziellen bevorzugt ist die erfindungsgemäße Verwendung von Verbindungen der allgemeinen Formel (I), die durch die Formeln (la) bis (lo) beschrieben werden, Especially preferred is the use according to the invention of compounds of the general formula (I) which are described by the formulas (Ia) to (Io)
worin wherein
[X-Y] für die Gruppierung  [X-Y] for grouping
[x-Y]1 steht,[xY] 1 stands,
Q für die Gruppierungen Q-1 bis Q-6 Q for the groupings Q-1 to Q-6
steht, wobei R13, R14, R15, R16, R17, R18, R19, R20, R23, R24, R25, R26, R28, R29, R30, R31, R32, R34, R35 und R36 sowie A1 bis A9 jeweils die Bedeutung gemäß der nachstehenden Definitionen haben und wobei der Pfeil für eine Bindung zur jeweiligen Gruppierung C-R6 in den vorgenannten Formeln (la) bis (lo) steht, where R 13 , R 14 , R 15 , R 16 , R 17 , R 18 , R 19 , R 20 , R 23 , R 24 , R 25 , R 26 , R 28 , R 29 , R 30 , R 31 , R 32 , R 34 , R 35 and R 36 and A 1 to A 9 each have the meaning as defined below and wherein the arrow for a bond to the respective group CR 6 in the aforementioned formulas (la) to (lo) .
R5 für Hydroxy, (Ci-Ce)-Alkoxy, Aryloxy, (C3-Cr,)-Cycloalkyloxy, (C2-C6)-Alkenyloxy, (C2-C6)-Alkenyl-(Ci-C6)-alkyloxy, (Ci-C6)-Alkoxy-(Ci-C6)-alkyloxy, (Ci-C6)- Alkylcarbonyloxy, Arylcarbonyloxy, Heteroarylcarbonyloxy, (Ca-Ce)- Cycloalkylcarbonyloxy, (d-CeJ-Alkoxycarbonyloxy, (Cz-Ce)- Alkenyloxycarbonyloxy, Aryloxy-(d-C6)-alkyloxy, Aryl-(d-C6)-alkyloxy, (d-Ce)- Alkoxy-(Ci-C6)-alkoxy-(Ci-C6)-alkyloxy, (Ci-C6)-Alkylthio-(Ci-C6)-alkyloxy, Ths[(Ci-C6)-alkyl]silyloxy, (Ci-C6)-Alkyl-Bis[(Ci-C6)-alkyl]silyloxy, (Ci-C6)-Alkyl- bis(Aryl)silyloxy, Aryl-bis[(Ci-Cr>)— alkyljsilyloxy, Cycloalkyl-bis[(Ci-C6)- alkyljsilyloxy, Halo-bis[(Ci-C6)-alkyl]silyloxy, Tris[(Ci-C6)-alkyl]silyl-(Ci-C6)- alkoxy-(Ci-C6)-alkyloxy, steht, R 5 is hydroxy, (C 1 -C 6 ) -alkoxy, aryloxy, (C 3 -C 8) -cycloalkyloxy, (C 2 -C 6 ) -alkenyloxy, (C 2 -C 6 ) -alkenyl- (C 1 -C 6 ) -alkyloxy, (C 1 -C 6 ) -alkoxy- (C 1 -C 6 ) -alkyloxy, (C 1 -C 6 ) -alkylcarbonyloxy, arylcarbonyloxy, heteroarylcarbonyloxy, (Ca-Ce) -cycloalkylcarbonyloxy, (d-CeJ-alkoxycarbonyloxy, (Cz-Ce Alkenyloxycarbonyloxy, aryloxy- (C 1 -C 6 ) -alkyloxy, aryl- (C 1 -C 6 ) -alkyloxy, (C 1 -C 6 ) -alkoxy- (C 1 -C 6 ) -alkoxy- (C 1 -C 6 ) -alkyloxy, (C 1 -C 6 ) -alkylthio (C 1 -C 6 ) -alkyloxy, Ths [(C 1 -C 6 ) -alkyl] silyloxy, (C 1 -C 6 ) -alkyl-bis [(C 1 -C 6 ) -alkyl ] silyloxy, (C 1 -C 6 ) -alkyl bis (aryl) silyloxy, aryl-bis [(C 1 -C 8) 2 -alkyl] silylxy, cycloalkyl-bis [(C 1 -C 6 ) -alkyl] ssilyloxy, halo-bis [(ci) C 6 ) -alkyl] silyloxy, tris [(C 1 -C 6 ) -alkyl] silyl- (C 1 -C 6 ) -alkoxy- (C 1 -C 6 ) -alkyloxy,
R6 für Nitro, Amino, Hydroxy, Hydrothio, Thiocyanato, Isothiocyanato, Fluor, Chlor, Brom, lod, (CrC6)-Alkyl, (C3-C6)-Cycloalkyl, (C2-C6)-Alkenyl, (C4-C6)- Cycloalkenyl, (C2-C6)-Alkinyl, Aryl-(C2-C6)-alkinyl, Tris[(Ci-C6)-alkyl]silyl-(C2-C6)- alkinyl, Aryl, Aryl-(Ci-C6)-alkyl, Aryl-(Ci-C6)-alkoxy, Heteroaryl, (d-C6)- Haloalkyl, (C3-C6)-Halocycloalkyl, (C2-C6)-Haloalkenyl, (Ci-C6)-Alkoxy, (d-Ce)- Haloalkoxy, Aryloxy, Heteroaryloxy, (C3-C-6)-Cycloalkyloxy, (C3-C6)-Cycloalkyl- (Ci-C6)-alkoxy, (C2-C6)- (C2-C6)-Alkenyloxy, (C2-C6)-Alkinyl-(C2-C6)-alkyloxy, Hydroxy-(Ci-C6)-alkyl, (Ci-C6)-Alkoxy-(Ci-C6)-alkyl, Aryloxy-(Ci-Ce)-alkyl, Heteroaryloxy-(Ci-C6)-alkyl, (CrC6)-Alkylthio, (Ci-C6)-Haloalkylthio, (Ci-C6)- Alkoxycarbonyl-(Ci-C6)-alkylthio, Arylthio, (Ca-Ce Cycloalkylthio, Heteroarylthio, (Ci-C6)-Alkylthio-(Ci-C6)-alkyl, (Ci-C6)-Alkylamino, Bis[(Ci-C6)-alkyl]amino, (C2-C6)-Alkenylamino, (C3-C6)-Cycloalkylamino, (CrCeJ-Alkylcarbonylamino, (Ca-Ce Cycloalkylcarbonylamino, Arylcarbonylamino, Heteroarylcarbonylamino, Formylamino, (Ci-C6)-Haloalkylcarbonylamino, (Ci-C6)-Alkoxycarbonylamino, (Ci-C6)-Alkylaminocarbonylamino, (d-C6)-Alkyl[(Ci-C6)- Alkyl]aminocarbonylamino, (Ci-C6)-Alkylsulfonylamino, (Ca-Ce)- Cycloalkylsulfonylamino, Arylsulfonylamino, Hetarylsulfonylamino, Sulfonyl- (CrCc -haloalkylamino, Amino-(Ci-C6)-alkylsulfonyl, Amino-(CrC6)- haloalkylsulfonyl, (Ci-CeJ-Alkylaminosulfonyl, Bis[(Ci-C6)-alkyl]aminosulfonyl, (Ca-Ce Cycloalkylaminosulfonyl, (Ci-Cr -Haloalkylaminosulfonyl, R 6 represents nitro, amino, hydroxy, Hydrothio, thiocyanato, isothiocyanato, fluorine, chlorine, bromine, iodine, (CrC 6) alkyl, (C 3 -C 6) -cycloalkyl, (C 2 -C 6) alkenyl, (C 4 -C 6) - cycloalkenyl, (C 2 -C 6) alkynyl, aryl (C2-C6) -alkynyl, tris [(Ci-C6) alkyl] silyl (C2-C 6) - alkynyl, aryl, aryl (Ci-C 6) alkyl, aryl (Ci-C 6) alkoxy, heteroaryl, (dC 6) - haloalkyl, (C 3 -C 6) halocycloalkyl, (C 2 - C 6) haloalkenyl, (Ci-C 6) alkoxy, (d-Ce) - haloalkoxy, aryloxy, heteroaryloxy, (C3-C6) cycloalkyloxy, (C3-C6) cycloalkyl (Ci-C 6 ) -alkoxy, (C 2 -C 6 ) - (C 2 -C 6 ) -alkenyloxy, (C 2 -C 6 ) -alkynyl- (C 2 -C 6 ) -alkyloxy, Hydroxy (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -alkoxy- (C 1 -C 6 ) -alkyl, aryloxy- (C 1 -C 6 ) -alkyl, heteroaryloxy- (C 1 -C 6 ) -alkyl, ( C 1 -C 6 -alkylthio, (C 1 -C 6 ) -haloalkylthio, (C 1 -C 6 ) -alkoxycarbonyl- (C 1 -C 6 ) -alkylthio, arylthio, (C 1 -C 6 -cycloalkylthio, heteroarylthio, (C 1 -C 6 ) -alkylthio - (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -alkylamino, bis [(C 1 -C 6 ) -alkyl] -amino, (C 2 -C 6 ) -alkenylamino, (C 3 -C 6 ) -cycloalkylamino, (CrCeJ) Alkylcarbonylamino, (C 1 -C 6 -cycloalkylcarbonylamino, arylcarbonylamino, heteroarylcarbonylamino, formylamino, (C 1 -C 6) -haloalkylcarbonylamino, (C 1 -C 6) -alkoxycarbonylamino, (C 1 -C 6) -alkylaminocarbonylamino, (C 1 -C 6) -alkyl [( C6) alkyl] aminocarbonylamino, (C 1 -C 6) -alkylsulfonylamino, (C 1 -C 6) -cycloalkylsulfonylamino, arylsulfonylamino, hetarylsulfonylamino, sulfonyl- (C 1 -C 6 -haloalkylamino, amino- (C 1 -C 6) -alkylsulfonyl, amino- (C 1 -C 6) -cycloalkylsulfonylamino haloalkylsulfonyl, (C 1 -C 6 -alkylaminosulfonyl, bis [(C 1 -C 6) -alkyl] aminosulfonyl, (C 1 -C 6 -cycloalkylaminosulfonyl, (C 1 -C 6 -haloalkylaminosulfonyl)
Heteroarylaminosulfonyl, Arylaminosulfonyl, Aryl-(Ci-C6)-alkylaminosulfonyl, (Ci-C6)-Alkylsulfonyl, (C3-C6)-Cycloalkylsulfonyl, Arylsulfonyl. (Ci-C6)- Alkylsulfinyl, (C3-C6)-Cycloalkylsulfinyl, Arylsulfinyl, N,S-Bis[(CrC6)- alkyl]sulfonimidoyl, S-(Ci-C6)-Alkylsulfonimidoyl, (d-Ce)- Alkylsulfonylaminocarbonyl, (C3-C6)-Cycloalkylsulfonylaminocarbonyl, Aryl- (Ci-C6)-alkylcarbonylamino, (C3-C6)-Cycloalkyl-(Ci-C6)-alkylcarbonylamino, Heteroarylcarbonylamino, (Ci-C6)-Alkoxy-(Ci-C6)-alkylcarbonylamino, Hydroxy- (Ci-Cö)-alkylcarbonylamino, (Ci-C6)-Alkoxycarbonylamino-(CrC6)- alkylcarbonylamino, Cyano, Cyano-(Ci-C6)-alkyl, Hydroxycarbonyl, (Ci-Cr,)- Alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(d-C6)- alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C6)-alkoxycarbonyl, (C2-Ce)- Alkenyloxycarbonyl, (C2-C6)-Alkinyloxycarbonyl, (d-CeJ-Haloalkyloxycarbonyl, (Ci-C6)-Alkoxy-(Ci-C6)-alkoxycarbonyl, (C2-C6)-Alkenyloxy-(Ci-C6)- alkoxycarbonyl, (Ci-Cö)-Alkylamino-(Ci-C6)-alkoxycarbonyl, Tris[(Ci-C6)- alkyl]silyloxy-(Ci-C6)-alkoxycarbonyl, Bis[(Ci-C6)-Alkyl]amino-(Ci-C6)- alkoxycarbonyl, (Ci-C6)-Alkyl[(Ci-C6)-alkyl]amino-(Ci-C6)-alkoxycarbonyl, Cyano-(Ci-Cö)-alkoxycarbonyl, Heterocyclyl-N-(CrC6)-alkoxycarbonyl, Heteroarylaminosulfonyl, arylaminosulfonyl, aryl (Ci-C6) alkylaminosulfonyl, (Ci-C 6) alkylsulfonyl, (C 3 -C 6) cycloalkylsulfonyl, arylsulfonyl. (Ci-C 6) - alkylsulfinyl, (C3-C 6) cycloalkylsulfinyl, arylsulfinyl, N, S-bis [(CrC 6) - alkyl] sulfonimidoyl, S- (Ci-C6) -Alkylsulfonimidoyl, (d-Ce) Alkylsulfonylaminocarbonyl, (C 3 -C 6) -cycloalkylsulfonylaminocarbonyl, aryl- (C 1 -C 6) -alkylcarbonylamino, (C 3 -C 6) -cycloalkyl- (C 1 -C 6) -alkylcarbonylamino, heteroarylcarbonylamino, (C 1 -C 6) -alkoxy- (C 1 -C 4) -cycloalkyl C 6) -alkylcarbonylamino, hydroxy- (C 1 -C 6) -alkylcarbonylamino, (C 1 -C 6) -alkoxycarbonylamino- (C 1 -C 6) -alkylcarbonylamino, cyano, cyano- (C 1 -C 6) -alkyl, hydroxycarbonyl, (C 1 -C 8) 2 - Alkoxycarbonyl, (C3-C6) -cycloalkoxycarbonyl, (C3-C6) -cycloalkyl- (d-C6) -alkoxycarbonyl, aryloxycarbonyl, aryl- (Ci-C6) -alkoxycarbonyl, (C2-Ce) -alkenyloxycarbonyl, (C2-C6 ) Alkynyloxycarbonyl, (C 1 -C 6 -haloalkyloxycarbonyl, (C 1 -C 6 ) -alkoxy- (C 1 -C 6 ) -alkoxycarbonyl, (C 2 -C 6 ) -alkenyloxy- (C 1 -C 6 ) -alkoxycarbonyl, C 6) -alkylamino- (C 1 -C 6) -alkoxycarbonyl, tris [(C 1 -C 6) -alkyl] silyloxy- (C 1 -C 6) -alkoxycarbonyl, bis [(C 1 -C 6) -alkyl] amino- (C 1 -C 6) - alkoxycarbonyl, (C 1 -C 6) -alkyl [(C 1 -C 6) -alkyl] a mino- (C 1 -C 6) -alkoxycarbonyl, cyano- (C 1 -C 6) -alkoxycarbonyl, heterocyclyl-N- (C 1 -C 6) -alkoxycarbonyl,
Heteroaryloxycarbonyl, Heteroaryl-(Ci-C6)-alkoxycarbonyl, Heterocyclyl-(Ci-Cr,)- alkoxycarbonyl, Heterocyclyloxycarbonyl, (C2-C6)-Alkenyl-(d-C6)- alkoxycarbonyl, (C2-C6)-Alkinyl-(Ci-C6)-alkoxycarbonyl, Aryl-(C2-Ce)- alkinyloxycarbonyl, Aryl-(C2-C6)-alkenyloxycarbonyl, Aminocarbonyl, (Ci-Ce)- Alkylaminocarbonyl, Bis[(Ci-C6)-alkyl]aminocarbonyl, (Ci-C6)-Alkyl[(Ci-C6)- Alkyljaminocarbonyl, (Ci-C6)-Alkyl[(Ci-C6)-Alkoxy]aminocarbonyl, (C2-C6)- Alkenylaminocarbonyl, (Ca-CeJ-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C6)-alkylaminocarbonyl, Heteroaryl-(Ci-C6)-alkylaminocarbonyl, Cyano- (CrCe alkylaminocarbonyl, (Ci-Cr -Haloalkylaminocarbonyl, (C2-C6)-Alkinyl- (Ci-C6)-alkylaminocarbonyl, (CrCe AIkoxycarbonylaminocarbonyl, Aryl-(Ci-Cr,)- alkoxycarbonylaminocarbonyl, Hydroxycarbonyl-(CrC6)-alkyl, (Ci-Ce)- Aikoxycarbonyl-(Ci-C6)-alkyl, (C3-C6)-Cycloalkoxycarbonyl-(CrC6)-alkyl, (C3-C6)-Cycloalky!-(Ci-C6)-alkoxycarbonyl-(Ci-C6)-alkyl, (C2-C6)- Alkenyloxycarbonyl-(Ci-C6)-alkyl, Aryl-(Ci-Cr>)-alkoxycarbonyl-(Ci-C6)-alkyl, (Ci-C6)-Alkylaminocarbonyl-(CrC6)-alkyl, Aminocarbonyl-(Ci-C6)-alkyl, Heteroaryloxycarbonyl, heteroaryl- (C 1 -C 6) -alkoxycarbonyl, heterocyclyl- (C 1 -C 4) -alkoxycarbonyl, heterocyclyloxycarbonyl, (C 2 -C 6) -alkenyl- (C 1 -C 6) -alkoxycarbonyl, (C 2 -C 6) -alkynyl- C 1 -C 6) -alkoxycarbonyl, aryl- (C 2 -C 6) -alkynyloxycarbonyl, aryl- (C 2 -C 6) -alkenyloxycarbonyl, aminocarbonyl, (C 1 -C 4) - Alkylaminocarbonyl, bis [(Ci-C6) -alkyl] aminocarbonyl, (Ci-C6) -alkyl [(Ci-C6) - alkyl] aminocarbonyl, (Ci-C6) -alkyl [(Ci-C6) -alkoxy] aminocarbonyl, (C2 -C6) - alkenylaminocarbonyl, (Ca-CeJ-cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (Ci-C6) -alkylaminocarbonyl, heteroaryl- (Ci-C6) -alkylaminocarbonyl, cyano- (CrCe alkylaminocarbonyl, (Ci-Cr -Haloalkylaminocarbonyl, (C2 -C 6) alkynyl (C 1 -C 6) -alkylaminocarbonyl, (C 1 -C 4 -alkoxycarbonylaminocarbonyl, aryl- (C 1 -C 8) -alkoxycarbonylaminocarbonyl, hydroxycarbonyl- (C 1 -C 6) -alkyl, (C 1 -C 6) -acoxycarbonyl- (C 1 -C 6) alkyl, (C3-C6) -Cycloalkoxycarbonyl- (CRC6) alkyl, (C 3 -C 6) -Cycloalky - (Ci-C 6) alkoxycarbonyl (Ci-C6) alkyl, (C 2 -C 6 ) - alkenyloxycarbonyl- (Ci-C6) -alkyl, aryl- (Ci-Cr > ) -alkoxycarbonyl- (Ci-C6) -alkyl, (Ci-C6) -Alkylaminocarbonyl- (CrC6) -alkyl, aminocarbonyl- (Ci-) C6) alkyl,
Bis[(Ci-C6)-alkyl]aminocarbonyl-(Ci-C6)-alkyl, (Ca-Cr -Cycloalkylaminocarbonyl- (Ci-C6)-alkyl, Aryl-(Ci-C6)-alkylaminocarbonyl-(Ci-C6)-alkyl, Heteroaryl-(Ci-C6)- alkylaminocarbonyl-(Ci-Cö)-alkyl, Cyano-(Ci-C6)-alkylaminocarbonyl-(Ci-C6)- alkyl, (Ci-C6)-Ha!oa!kylaminocarbonyl-(Ci-C6)-alkyl, (C2-C6)-Alkinyl-(Ci-C6)- alkylaminocarbonyl-(Ci-C6)-alkyl, (C3-C6)-Cycloalkyl-(Ci-C6)- alkylaminocarbonyl-(CrC6)-alkyl, (CrC6)-Alkoxycarbonylaminocarbonyl- (Ci-C6)-alkyl, Aryl-(Ci-C6)-alkoxycarbonylaminocarbonyl-(Ci-C6)-alkyl, (Ci-Ce)- Alkoxycarbonyl-(Ci-C6)-alkylaminocarbonyl, Hydroxycarbonyl-(Ci-C6)- alkylaminocarbonyl, Ary!-(Ci-C6)-alkoxycarbonyl-(Ci-C6)-alkylaminocarbonyl, Aminocarbonyl-(Ci-C6)-alkylaminocarbonyl, (CrCeJ-Alkylaminocarbonyl- (Ci-C6)-alkylaminocarbonyl, Bis [(Ci-C6) -alkyl] aminocarbonyl- (Ci-C6) -alkyl, (Ca-Cr -cycloalkylaminocarbonyl- (Ci-C 6 ) -alkyl, aryl- (Ci-C6) -alkylaminocarbonyl- (Ci-C 6 ) -alkyl, heteroaryl- (C 1 -C 6 ) -alkylaminocarbonyl- (C 1 -C 6 ) -alkyl, cyano- (C 1 -C 6 ) -alkylaminocarbonyl- (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -Ha Cylaminocarbonyl- (C 1 -C 6 ) -alkyl, (C 2 -C 6 ) -alkynyl- (C 1 -C 6 ) -alkylaminocarbonyl- (C 1 -C 6 ) -alkyl, (C 3 -C 6 ) -cycloalkyl- (C 1 -C 6 ) -alkylaminocarbonyl- (C 1 -C 6) -alkyl, (C 1 -C 6 ) -alkoxycarbonylaminocarbonyl- (C 1 -C 6 ) -alkyl, aryl- (C 1 -C 6 ) -alkoxycarbonylaminocarbonyl- (C 1 -C 6 ) -alkyl, Ce) - alkoxycarbonyl- (C 1 -C 6) -alkylaminocarbonyl, hydroxycarbonyl- (C 1 -C 6) -alkylaminocarbonyl, aryl- (C 1 -C 6) -alkoxycarbonyl- (C 1 -C 6) -alkylaminocarbonyl, aminocarbonyl- (C 1 -C 6) - alkylaminocarbonyl, (C 1 -C 6 -alkylaminocarbonyl- (C 1 -C 6) -alkylaminocarbonyl,
(C3-C6)-Cycloalkylaminocarbonyl-(Ci-C6)-alkylaminocarbonyl, (Ca-Ce)- Cycloalkyl-(Ci-C6)-alkylaminocarbonyl, (C3-C6)-Cycloalkyl-(Ci-C6)- alkylaminocarbonyl-(Ci-C6)-alkyl, (Ca-CeV-CycloalkyKCrCe)- alkylaminocarbonyl-(Ci-C6)-alkylaminocarbonyl, (C2-C6)-Alkenyl-(d-C6)- alkylaminocarbonyl, (C2-C6)-Alkenylaminocarbonyl-(Ci-C6)-alkyl, (C2-Ce)- Alkenyl-(Ci-C6)-alkylaminocarbonyl-(Ci-C6)-alkyl, (Ci-C6)-Alkylcarbonyl, (C3-C6)- Cycloalkylcarbonyl, Arylcarbonyl, Formyl, HydroxyiminomethyL (C 3 -C 6 ) -cycloalkylaminocarbonyl- (C 1 -C 6 ) -alkylaminocarbonyl, (Ca-Ce) -cycloalkyl- (C 1 -C 6 ) -alkylaminocarbonyl, (C 3 -C 6 ) -cycloalkyl- (C 1 -C 6 ) -alkylaminocarbonyl - (Ci-C6) -alkyl, (Ca-CeV-CycloalkyKCrCe) - alkylaminocarbonyl- (Ci-C6) -alkylaminocarbonyl, (C2-C6) -alkenyl- (d-C6) - alkylaminocarbonyl, (C2-C6) -alkenylaminocarbonyl - (Ci-C6) alkyl, (C2-Ce) - alkenyl, (Ci-C6) alkylaminocarbonyl (Ci-C 6) alkyl, (Ci-C 6) alkylcarbonyl, (C 3 -C 6 ) - cycloalkylcarbonyl, arylcarbonyl, formyl, hydroxyiminomethyl
Aminoiminomethyl, (CrCeJ-Alkoxyiminomethyl, (CrCeJ-Alkylaminoiminomethyl, Bis[(Ci-C6)-alkyl]aminoiminomethyl, (C3-C6)-Cycloalkoxyiminomethyl, (Ca-Ce)- Cycloalkyl-(Ci-C6)-alkoximinomethyl, Aryloximinomethyl, Aryl-(Ci-Ce)- alkoxyiminomethyl, Aryl-(Ci-C6)-alkylaminoiminomethyl, (C2-Ce)- Alkenyloxyiminomethyl, Arylaminoiminomethyl, Arylsulfonylaminoiminomethyl, Heieroaryl-(Ci-C6)-alkyl, Heierocyclyl-(Ci-C6)-alkyl, Aminoiminomethyl, (CrCeJ-alkoxyiminomethyl, (CrCeJ-alkylaminoiminomethyl, bis [(Ci-C6) -alkyl] aminoiminomethyl, (C3-C6) -cycloalkoxyiminomethyl, (Ca-Ce) -cycloalkyl- (Ci-C6) -alkoximinomethyl, aryloximinomethyl, Aryl- (C 1 -C 6) -alkoxyiminomethyl, aryl- (C 1 -C 6) -alkylaminoiminomethyl, (C 2 -C 6) -alkenyloxyiminomethyl, arylaminoiminomethyl, arylsulfonylaminoiminomethyl, Heieroaryl- (Ci-C 6 ) -alkyl, Heierocyclyl- (Ci-C 6 ) alkyl,
Hydroxycarbonylheterocyclyl, (d-d -Alkoxycarbonylheterocyclyl, (d-d)- Alkenyloxycarbonylheterocyclyl, (C2-C6)-Alkenyl-(Ci-d)- alkoxycarbonylheterocyclyl, Aryl-(CrC6)-alkoxycarbonylheterocyclyl, (d-d)- Cycloalkoxycarbonylheterocyclyl, (C3-C6)-Cycloalkyl-(Ci-d.)- alkoxycarbonylheterocyclyl, Aminocarbonylheterocyclyl, (Ci-d)- Alkylaminocarbonylheterocyclyl, Bis[(d-d)-Alkyl]aminocarbonylheterocyclyl, (Ca-Ce Cycloalkylaminocarbonylheterocyclyl, Aryl-(d-d)- alkylaminocarbonylheterocyclyl, (C2-C6)-Alkenylaminocarbonylheterocyclyl, Hydroxycarbonylheterocyclyl-(Ci-C6)-alkyl, (Ci-d)-Alkoxycarbonylheterocyclyl- (Ci-C6)-alkyl, Hydroxycarbonyl-(C3-C6)-cycloalkyl-(Ci-C6)-alkyl, (Ci-d)- Alkoxycarbonyl-(C3-C6)-cycloalkyl-(Ci-C6)-alkyl, Hydroxyaminocarbonyl, (Ci-C6)-Alkoxyaminocarbonyl, Aryi-(Ci-C6)-alkoxyaminocarbonyl, Heterocyclyl, (d-C6)-Alkylcarbonyloxy, Arylcarbonyloxy, Heteroarylcarbonyloxy, (d-d)- Cycloalkylcarbonyloxy, (Ci-d)-Alkoxycarbonyloxy, (d-d)- Alkenyloxycarbonyloxy, Aminosulfonyl, (CrCeJ-Alkoxycarbonyl-heterocyclyl-N- carbonyl, (Ci-C6)-Alkoxycarbonyl-(Ci-C6)-alkyl-heterocyclylidenaminocarbonyl, (Ci-C6)-Alkoxycarbonylheterocyclyliden-(Ci-C6)-alkylaminocarbonyl, (Ci-Ce)- Alkoxycarbonyl-(Ci-C6)-Alkyl((Ci-C6)-alkyl)aminocarbonyl, (Ci-d)- Alkoxycarbonyl-(di-d)-cycloalkylidenaminocarbonyl, Heterocyclyl-N-carbonyl, (Ci-C6)-Alkoxy-(CrC6)-alkylaminocarbonyl steht, Hydroxycarbonylheterocyclyl, (dd-alkoxycarbonylheterocyclyl, (dd) -alkenyloxycarbonylheterocyclyl, (C 2 -C 6) -alkenyl- (C 1 -d) -alkoxycarbonylheterocyclyl, aryl- (C 1 -C 6) -alkoxycarbonyl-heterocyclyl, (dd) -cycloalkoxycarbonyl-heterocyclyl, (C 3 -C 6) -cycloalkyl - (Ci-d.) - alkoxycarbonylheterocyclyl, aminocarbonylheterocyclyl, (Ci-d) - alkylaminocarbonylheterocyclyl, bis [(dd) -alkyl] aminocarbonylheterocyclyl, (Ca-Ce cycloalkylaminocarbonylheterocyclyl, aryl- (dd) -alkylaminocarbonylheterocyclyl, (C2-C6) - Alkenylaminocarbonylheterocyclyl, hydroxycarbonylheterocyclyl (C 1 -C 6 ) -alkyl, (C 1 -C 4) -alkoxycarbonylheterocyclyl (C 1 -C 6 ) -alkyl, hydroxycarbonyl- (C 3 -C 6 ) -cycloalkyl- (C 1 -C 6 ) -alkyl, ( Ci-d) - alkoxycarbonyl- (C3-C6) -cycloalkyl- (Ci-C6) -alkyl, hydroxyaminocarbonyl, (Ci-C6) -alkoxyaminocarbonyl, aryl- (Ci-C6) -alkoxyaminocarbonyl, heterocyclyl, (d-C6) -Alkylcarbonyloxy, arylcarbonyloxy, heteroarylcarbonyloxy, (dd) -cycloalkylcarbonyloxy, (Ci-d) -alkoxycarbonyloxy, (dd) -alkenyloxycarbonyloxy, aminosulfonyl, (CrCeJ Alkoxycarbonyl-heterocyclyl-N-carbonyl, (Ci-C6) -alkoxycarbonyl- (Ci-C6) -alkyl-heterocyclylidenaminocarbonyl, (Ci-C6) -alkoxycarbonylheterocyclyliden- (Ci-C6) -alkylaminocarbonyl, (Ci-Ce) - alkoxycarbonyl (C 1 -C 6) -alkyl (C 1 -C 6) -alkyl) aminocarbonyl, (C 1 -C 4) -alkoxycarbonyl- (di-d) -cycloalkylideneaminocarbonyl, heterocyclyl-N-carbonyl, (C 1 -C 6) -alkoxy- C 1 -C 6) -alkylaminocarbonyl,
R13, R14, R15 und R16 unabhängig voneinander für Wasserstoff, Fluor, Chlor, Brom, lod, Nitro, Amino, Cyano, (d-d)-Alkyl, gegebenenfalls substituiertes Phenyl, Heteroaryl, (C3-C6)-Cycloalkyl, (C4-C6)-Cycloalkenyl, (C2-C5)-Alkenyl, (d-d)- Alkinyl, (C2-C5)-Alkenyl-(Ci-C5)-alkyl, (C2-C5)-Alkinyl-(Ci-C5)-alkyl, Hydroxy, (Ci-C5)-Alkoxy, (Ci-C5)-Alkoxy-(Ci-C5)-alkoxy, (Ci-C5)-Alkoxy-(Ci-C5)-alkyl, Hydroxy-(Ci-C5)-alkyl, (Ci-C5)-Haloalkoxy, (Ci-C5)-Haloalkyl, (C2-C5)- Haloalkenyl, (C2-C5)-Haloalkinyl, (Ci-d)-Haloalkoxy-(Ci-d)-alkyl, (C1-C5)- Alkoxy-(Ci-C5)-haloalkyl, (Ci-C5)-Haloalkoxy-(Ci-C5)-haloalkyl, Hydrothio, (Ci-C5)-Alkylthio, (d-C5)-Haloalkylthio, (Ci-d)-Alkylthio-(Ci-d)-alkyl, (C1-C5)- Haloalkylthio-(Ci-C5)-alkyl, (Ci-C5)-Alkylamino, Bis-[(Ci-C5)-alkyl]amino, (C2-C5)-Alkenylamino, (C3-d)-Cycloalkylamino, (Ci-C5)-Alkylcarbonylamino, (C3-C6)-Cycloalkylcarbonylamino, Aryicarbonylamino, Heteroarylcarbonylamino, Formylamino, (Ci-C5)-Haloalkylcarbonylamino, (Ci-C5)-Alkoxycarbonylamino, (CrCsJ-Alkylaminocarbonylamino, (C1-C5)- Alkyl[(Ci-Cs)- Alkyljaminocarbonylamino, (Ci-Cr>)-Alkylsulfonylamino, (Ca-Ce)- Cycloalkylsulfonylamino, Arylsulfonylamino, Hetarylsulfonylamino, Sulfonyl- (CrC5)-haloalkylamino, Amino-(Ci-C5)-alkylsulfonyl, Amino-(Ci-C5)- haloalkylsulfonyl, (Ci-Cr -Alkylaminosulfonyl, Bis[(CrC5)-alkyl]aminosulfonyl, (C3-Cö)-Cycloalkylaminosulfonyl, (Ci-C5)-Haloalkylaminosulfonyl, R 13 , R 14 , R 15 and R 16 independently of one another represent hydrogen, fluorine, chlorine, bromine, iodine, nitro, amino, cyano, (dd) -alkyl, optionally substituted phenyl, heteroaryl, (C 3 -C 6 ) - Cycloalkyl, (C 4 -C 6 ) cycloalkenyl, (C 2 -C 5 ) alkenyl, (dd) alkynyl, (C 2 -C 5 ) alkenyl (Ci-C 5 ) alkyl, (C 2 -C 5 ) -alkynyl- (C 1 -C 5 ) -alkyl, hydroxy, (C 1 -C 5 ) -alkoxy, (C 1 -C 5 ) -alkoxy- (C 1 -C 5 ) -alkoxy, (C 1 -C 5 ) - Alkoxy- (C 1 -C 5 ) -alkyl, hydroxy- (C 1 -C 5 ) -alkyl, (C 1 -C 5 ) -haloalkoxy, (C 1 -C 5 ) -haloalkyl, (C 2 -C 5 ) -haloalkenyl, (C 2 -C 5 ) -haloalkynyl, (Ci-d) -haloalkoxy- (Ci-d) -alkyl, (C1-C5) -alkoxy- (Ci-C 5 ) -haloalkyl, (Ci-C 5 ) -haloalkoxy- (C 1 -C 5 ) -haloalkyl, hydrothio, (C 1 -C 5 ) -alkylthio, (C 1 -C 5 ) -haloalkylthio, (C 1 -C 4) -alkylthio (C 1 -C 4) -alkyl, (C 1 -C 5 ) -haloalkylthio (C 1 -C 5 ) -alkyl, (C 1 -C 5 ) -alkylamino, bis - [(C 1 -C 5 ) -alkyl] -amino, (C 2 -C 5 ) -alkenylamino, (C 3 -d) -cycloalkylamino, ( C 1 -C 5) -alkylcarbonylamino, (C 3 -C 6) -cycloalkylcarbonylamino, arylcarbonylamino, heteroarylcarbonylamino, Formylamino, (Ci-C5) -Haloalkylcarbonylamino, (Ci-C5) alkoxycarbonylamino, (CrCsJ-alkylaminocarbonylamino, (C1-C5) - alkyl [(Ci-Cs) - Alkyljaminocarbonylamino, (Ci-Cr>) alkylsulfonylamino, (Ca -Ce) - cycloalkylsulfonylamino, arylsulfonylamino, hetarylsulfonylamino, sulfonyl- (CrC5) -haloalkylamino, amino- (Ci-C5) -alkylsulfonyl, amino- (Ci-C5) -haloalkylsulfonyl, (Ci-Cr-alkylaminosulfonyl, bis [(CrC5) alkyl] aminosulfonyl, (C 3 -C 6) -cycloalkylaminosulfonyl, (C 1 -C 5) -haloalkylaminosulfonyl,
Heteroarylaminosulfonyl, Arylaminosulfonyl, Aryl-(Ci-C5)-alkylaminosulfonyl, (Ci-C5)-Alkylsulfonyl, (Ca-CeJ-Cycloalkylsulfonyl, Arylsuifonyi, Hydroxycarbonyl, (Ci-C5)-Alkoxycarbonyl, (Ca-Ce -Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl- (d-C5)-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(d-C5)-alkoxycarbonyl, (C2-C5)- Alkenyloxycarbonyl, (C2-Cr>)-Alkinyloxycarbonyl, Aminocarbonyl, (C1-C5)- Alkylaminocarbonyl, Bis[(CrC5)-alkyl]aminocarbonyl, (d-C5)-Alkyl[(Ci-C5)- Alkyljaminocarbonyl, (CrC5)-Alkyl-[(Ci-C5)-Alkoxy]aminocarbonyl, (C2-C5)- Alkenylaminocarbonyl, (C3-C6)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(CrC5)-alkylaminocarbonyl stehen, Heteroarylaminosulfonyl, arylaminosulfonyl, aryl- (Ci-C5) -alkylaminosulfonyl, (Ci-C5) -alkylsulfonyl, (Ca-CeJ-cycloalkylsulfonyl, arylsulfonyl, hydroxycarbonyl, (Ci-C5) -alkoxycarbonyl, (Ca-Ce-cycloalkoxycarbonyl, (C3 C6) cycloalkyl (d-C5) alkoxycarbonyl, aryloxycarbonyl, aryl (d-C5) -alkoxycarbonyl, (C2-C5) - alkenyloxycarbonyl, (C2-Cr>) -alkynyloxycarbonyl, aminocarbonyl, (C1-C5) - alkylaminocarbonyl, bis [(C 1 -C 5) -alkyl] aminocarbonyl, (C 1 -C 5) -alkyl [(C 1 -C 5) -alkyl] aminocarbonyl, (C 1 -C 5) -alkyl [(C 1 -C 5) -alkoxy] aminocarbonyl, (C 2 -C 5) ) - alkenylaminocarbonyl, (C 3 -C 6) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 5) -alkylaminocarbonyl,
A1, A2, A3 und A4 gleich oder verschieden sind und unabhängig voneinander für NA 1 , A 2 , A 3 and A 4 are the same or different and are independently N
(Stickstoff) oder die Gruppierungen C-H, C-CH3, C-F, C-Cl, C-Br, C-l, C-OCF3, C-OCH3, C-CF3, C-CO2H, C-CO2CH3 stehen, wobei jedoch in keinem Fall mehr als zwei N-Atome benachbart sind, (Nitrogen) or the groups CH, C-CH3, CF, C-Cl, C-Br, Cl, C-OCF3, C-OCH3, C-CF3, C-CO2H, C-CO2CH3, but in no case more than two N atoms are adjacent,
R17 und R18 unabhängig voneinander für Wasserstoff, Fluor, Chlor, Brom, lod, (C1-C5)- Alkyl, gegebenenfalls substituiertes Phenyl, Heteroaryl, Heterocyclyl, (Cs-Cr,)- Cycloalkyl, (C2-C5)-Alkenyl, (C2-C5)-Alkinyl, (CrC5)-Haloalkyl, (C1-C5)- Haloalkoxy-(Ci-C5)-alkyl, (Ci-C5)-Alkylthio-(Ci-C5)-alkyl, Hydroxycarbonyl, (Ci-C5)-Alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl- (Ci-C5)-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C5)-alkoxycarbonyl, (C2-C5)- Alkenyloxycarbonyl, (C2-Cs)-Alkinyloxycarbonyl, Aminocarbonyl, (C1-C5)- Alkylaminocarbonyl, Bis[(Ci-C5)-alkyl]aminocarbonyl, (Ci-C5)-Alkyl[(Ci-Cr>)- Alkyljaminocarbonyl, (Ci-C5)-Alkyl[(CrC5)-Alkoxy]aminocarbonyl, (C2-C5)- Alkenylaminocarbonyl, (Cs-CeJ-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C5)-alkylaminocarbonyl stehen, A5 für S (Schwefel), O (Sauerstoff) oder die Gruppierungen N-H, N-CH3, N-CH2CH3, N- CH(CH3)2, N-C02t-Bu, N-Aryl, N-Heteroaryl, N-Heterocyclyl steht, R 17 and R 18 independently of one another represent hydrogen, fluorine, chlorine, bromine, iodine, (C 1 -C 5 ) -alkyl, optionally substituted phenyl, heteroaryl, heterocyclyl, (Cs-Cr,) -cycloalkyl, (C 2 -C 5 ) alkenyl, (C 2 -C 5) alkynyl, (-C 5) haloalkyl, (C1-C5) - haloalkoxy (Ci-C 5) alkyl, (Ci-C 5) (Ci alkylthio-C 5 ) -alkyl, hydroxycarbonyl, (C 1 -C 5 ) -alkoxycarbonyl, (C 3 -C 6) -cycloalkoxycarbonyl, (C 3 -C 6) -cycloalkyl- (C 1 -C 5) -alkoxycarbonyl, aryloxycarbonyl, aryl- (C 1 -C 5) -alkoxycarbonyl , (C 2 -C 5) -alkenyloxycarbonyl, (C 2 -C 5) -alkynyloxycarbonyl, aminocarbonyl, (C 1 -C 5) -alkylaminocarbonyl, bis [(C 1 -C 5) -alkyl] aminocarbonyl, (C 1 -C 5) -alkyl [(ci) Cr>) - Alkyljaminocarbonyl, (Ci-C5) alkyl, [(CRC5) alkoxy] aminocarbonyl, (C2-C5) - alkenylaminocarbonyl, (Cs-CeJ-cycloalkylaminocarbonyl, arylaminocarbonyl, aryl (Ci-C5) alkylaminocarbonyl stand, A 5 for S (sulfur), O (oxygen) or the groupings NH, N-CH 3 , N-CH 2 CH 3 , N-CH (CH 3 ) 2 , N-CO 2 t-Bu, N-aryl, N-heteroaryl , N-heterocyclyl,
R19, R20, R23 und R24 unabhängig voneinander für Wasserstoff, (Ci-Cs)-Alkyl, Fluor, Chlor, Brom, lod, (C3-C6)-Cycloalkyl, gegebenenfalls substituiertes Phenyl,R 19 , R 20 , R 23 and R 24 independently of one another represent hydrogen, (C 1 -C 5) -alkyl, fluorine, chlorine, bromine, iodine, (C 3 -C 6) -cycloalkyl, optionally substituted phenyl,
Heteroaryl, Heterocyclyl, (C2-C5)-Alkenyl, Aryl-(Ci-C5)-alkyl, (CrC5)-Alkoxy, (Ci-C5)-Alkoxy-(Ci-Cr.)-alkoxy, (Ci-C5)-Alkoxy-(Ci-C5)-alkyl, Hydroxy, (C1-C5)- Haloalkyl, (Ci-C-5)-Haloalkylthio stehen, R19 und R23 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, Heteroaryl, heterocyclyl, (C 2 -C 5) alkenyl, aryl (Ci-C 5) alkyl, (CrC 5) alkoxy, (Ci-C 5) alkoxy (Ci-Cr.) - alkoxy, (C 1 -C 5 ) -alkoxy- (C 1 -C 5 ) -alkyl, hydroxy, (C 1 -C 5 ) -haloalkyl, (C 1 -C-5) -haloalkylthio, R 19 and R 23 with the atoms to which they are bonded to form a fully saturated or partially saturated, optionally further substituted 5 to 7-membered ring,
A6, A7 gleich oder verschieden sind und unabhängig voneinander für O (Sauerstoff), S (Schwefel), N-H, N-OCH3, N-CH3 oder die Gruppierung CR21R22 stehen, wobei jedoch in keinem Fall zwei N-, O- oder S-Atome benachbart sind, und wobei R21 und R22 in der Gruppierung CR21R22 jeweils gleiche oder verschiedene A 6 , A 7 are identical or different and independently of one another represent O (oxygen), S (sulfur), NH, N-OCH 3, N-CH 3 or the group CR 21 R 22 , but in no case are two N , O or S atoms are adjacent, and wherein R 21 and R 22 in the group CR 21 R 22 are each the same or different
Bedeutungen gemäß der nachstehenden Definition haben und R21 und R22 unabhängig voneinander für Wasserstoff, Fluor, Chlor, Brom, lod, (Ci-Ce)- Alkyl, gegebenenfalls substituiertes Phenyl, Heteroaryl, Heterocyclyl, (C3-C13)- Cycloalkyl, (C2-C5)-Alkenyl, (Ci-C5)-Alkoxy, (Ci-C5)-Alkoxy-(Ci-C5)-alkyl, Have meanings as defined below and R 21 and R 22 independently of one another represent hydrogen, fluorine, chlorine, bromine, iodine, (C 1 -C 6) -alkyl, optionally substituted phenyl, heteroaryl, heterocyclyl, (C 3 -C 13) -cycloalkyl, ( C 2 -C 5) alkenyl, (Ci-C 5) alkoxy, (Ci-C 5) alkoxy (Ci-C 5) alkyl,
(Ci-C5)-Haloalkoxy, (Ci-C5)-Haloalkyl, (Ci-C5)-Alkylthio, (CrC5)-Haloalkylthio, (Ci-C5)-Alkylthio-(CrC5)-alkyl, Hydroxycarbonyl, (Ci-CsJ-Alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(CrC5)-alkoxycarbonyl,(C 1 -C 5 ) -haloalkoxy, (C 1 -C 5 ) -haloalkyl, (C 1 -C 5 ) -alkylthio, (C 1 -C 5 ) -haloalkylthio, (C 1 -C 5 ) -alkylthio (C 1 -C 5 ) -alkyl, hydroxycarbonyl, (C 1 -C 5 -alkoxycarbonyl, (C 3 -C 6) -cycloalkoxycarbonyl, (C 3 -C 6) -cycloalkyl- (C 1 -C 5) -alkoxycarbonyl,
Aryloxycarbonyl, Aryl-(Ci-Cr3)-alkoxycarbonyl, (C2-C5)-Alkenyloxycarbonyl, (C2-C5)-Alkinyloxycarbonyl, Aminocarbonyl, (Ci-C5)-Alkylaminocarbonyl, Bis[(Ci-Cr>)-alkyl]aminocarbonyl, (Ci-C5)-Alkyl[(Ci-C5)-Alkyl]aminocarbonyl, (Ci-C5)-Alkyl[(Ci-C5)-Alkoxy]aminocarbonyl, (C2-C5)-Alkenylaminocarbonyl, (Cs-CeJ-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-Cs)- alkylaminocarbonyl, Amino, (Ci-Cr))-Alkylamino, (Ca-CeJ-Cycloalkylamino, Bis- [(CrC5)-Alkyl]amino stehen, R25, R26, R28 und R29 unabhängig voneinander für Wasserstoff, (Ci-C-5)-Alkyl, Fluor, Chlor, Brom, lod, (C3-Cö)-Cycloalkyl, gegebenenfalls substituiertes Phenyl, Heteroaryl, Heterocyclyl, (C2-C5)-Alkenyl, Aryl-(Ci-C5)-alkyl, (CrC5)-Alkoxy, (CrC5)-Haloalkyl stehen, Aryloxycarbonyl, aryl (Ci-Cr 3) -alkoxycarbonyl, (C2-C5) alkenyloxycarbonyl, (C 2 -C 5) -alkynyloxycarbonyl, aminocarbonyl, (Ci-C5) alkylaminocarbonyl, bis [(Ci-Cr>) alkyl ] aminocarbonyl, (C 1 -C 5) -alkyl [(C 1 -C 5) -alkyl] aminocarbonyl, (C 1 -C 5) -alkyl [(C 1 -C 5) -alkoxy] -aminocarbonyl, (C 2 -C 5) -alkenylaminocarbonyl, (Cs -CeJ-cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (Ci-Cs) - alkylaminocarbonyl, amino, (Ci-Cr)) - alkylamino, (Ca-CeJ-cycloalkylamino, bis- [(CrC5) -alkyl] amino, R 25 , R 26 , R 28 and R 29 independently of one another are hydrogen, (C 1 -C 5) -alkyl, fluorine, chlorine, bromine, iodine, (C 3 -C 6) -cycloalkyl, optionally substituted phenyl, heteroaryl, heterocyclyl, (C 2 -C 5) alkenyl, aryl (Ci-C 5) alkyl, (CrC 5) alkoxy, (CrC 5) -haloalkyl stand,
A8 für O (Sauerstoff), S (Schwefel), N-H, N-CH3, N-OCH3 oder die Gruppierung CHR27 steht und wobei R27 in der Gruppierung CHR27 die Bedeutung gemäß der nachstehenden Definition hat, A 8 is O (oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the moiety CHR 27 , and wherein R 27 in the moiety CHR 27 has the meaning as defined below,
R27 für Wasserstoff, Fluor, Chlor, Brom, lod, (Ci-Cs)-Alkyl, Aryl, Heteroaryl, R 27 is hydrogen, fluorine, chlorine, bromine, iodine, (C 1 -C 5) -alkyl, aryl, heteroaryl,
Heterocyclyl, (C3-C6)-Cycloalkyl, (C2-C5)-Alkenyl, (d-C5)-Alkoxy, (C1-C5)- Haloalkoxy, (Ci-C5)-Haloalkyl, (Ci-C5)-Alkylthio, (Ci-C5)-Haloalkylthio, Heterocyclyl, (C 3 -C 6) -cycloalkyl, (C 2 -C 5) alkenyl, (dC 5) alkoxy, (C1-C5) - haloalkoxy, (Ci-C5) haloalkyl, (Ci-C 5 ) -alkylthio, (C 1 -C 5 ) -haloalkylthio,
Hydroxycarbonyl, (Ci-Cs)-Alkoxycarbonyl, (C C6)-Cycloalkoxycarbonyl, Aryl- (d-C5)-alkoxycarbonyl, (C2-C5)-Alkenyloxycarbonyl, (C2-C5)-Alkinyloxycarbonyl, Aminocarbonyl, (Ci-CsJ-Alkylaminocarbonyl, Bis[(d-C5)-alkyl]aminocarbonyl, (Ci-C5)-Alkyl[(Ci-C5)-Alkyl]aminocarbonyl, (Ci-C5)-Alkyl[(Ci-C5)- Alkoxy]aminocarbonyl, (C2-C5)-Alkenylaminocarbonyl, (Ca-Ce)- Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C5)-alkylaminocarbonyl, Amino, (Ci-C5)-Alkylamino, (Ca-CeJ-Cycloalkylamino, Bis-[(Ci-C5)-Alkyl]amino steht, Hydroxycarbonyl, (C 1 -C 6) -alkoxycarbonyl, (C -C 6) -cycloalkoxycarbonyl, aryl- (C 1 -C 5) -alkoxycarbonyl, (C 2 -C 5) -alkenyloxycarbonyl, (C 2 -C 5) -alkynyloxycarbonyl, aminocarbonyl, (C 1 -C 5) -cycloalkoxycarbonyl, alkylaminocarbonyl, bis [(d-C5) alkyl] aminocarbonyl, (Ci-C 5) alkyl [(Ci-C5) alkyl] aminocarbonyl, (Ci-C 5) alkyl [(Ci-C 5) - Alkoxy] aminocarbonyl, (C2-C5) alkenylaminocarbonyl, (Ca-Ce) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (Ci-C5) -alkylaminocarbonyl, amino, (Ci-C5) -alkylamino, (Ca-CeJ-Cycloalkylamino, Bis - [(C 1 -C 5) -alkyl] -amino,
R31 , R32, R34, R35 und R36 unabhängig voneinander für Wasserstoff, (Ci-Cs)-Alkyl, Fluor, Chlor, Brom, lod, (Ca-CeJ-Cycloalkyl, gegebenenfalls substituiertes Phenyl, Heteroaryl. Heterocyclyl, (C2-C5)-Alkenyl, (Ci-C5)-Alkoxy, (C1-C5)- Haloalkyl, (CrC5)-Alkylthio, (Ci-C5)-Haloalkylthio stehen, R 31 , R 32 , R 34 , R 35 and R 36 independently of one another represent hydrogen, (C 1 -C 5) -alkyl, fluorine, chlorine, bromine, iodine, (C 1 -C 6 -cycloalkyl, optionally substituted phenyl, heteroaryl, heterocyclyl, (C 2 -C 5) alkenyl, (Ci-C 5) alkoxy, (C1-C5) - haloalkyl, (CrC 5) alkylthio, (Ci-C 5) are haloalkylthio,
A9 für O (Sauerstoff), S (Schwefel), N-H, N-CH3, N-OCH3 oder die Gruppierung CHR steht und wobei R33 in der Gruppierung CHR33 die Bedeutung gemäß der nachstehenden Definition hat und A 9 is O (oxygen), S (sulfur), NH, N-CH 3, N -OCH 3 or the group CHR and wherein R 33 in the group CHR 33 has the meaning as defined below and
R33 für Wasserstoff, Halogen, (Ci-CsJ-Alkyl, gegebenenfalls substituiertes Phenyl, Heteroaryl, Heterocyclyl, (C3-C6)-Cycloalkyl, (C2-C5)-Alkenyl, (CrC5)-Alkoxy, (Ci-Cr>)-Alkoxy-(Ci-C5)-alkyl, (CrC5)-Haloalkoxy, (Ci-C5)-Haloalkyl, (C1-C5)- Alkylthio, (Ci-C-5)-Haloalkylthio, Hydroxycarbonyl, (Ci-C5)-Alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, Aryl-(Ci-C5)-alkoxycarbonyl, (C2-C5)- Alkenyloxycarbonyl, (C2-C5)-Alkinyloxycarbonyl, Aminocarbonyl, (C1-C5)- Alkylaminocarbonyl, Bis[(Ci-C5)-alkyl]aminocarbonyl, (Ci-C-5)-Alkyl[(Ci-C5)- Alkyl]aminocarbonyl, (Ci-C5)-Alkyl[(Ci-C5)-Alkoxy]aminocarbonyl, (C2-C5)- Alkenylaminocarbonyl, (C3-C6)-Cycloalkylaminocarbonyl, Arylaminocarbonyl,R 33 is hydrogen, halogen, (C 1 -C 8 -alkyl, optionally substituted phenyl, heteroaryl, heterocyclyl, (C 3 -C 6 ) -cycloalkyl, (C 2 -C 5 ) -alkenyl, (C 1 -C 5 ) -alkoxy, (Ci -C r>) alkoxy (Ci-C 5) alkyl, (CrC 5) haloalkoxy, (Ci-C5) haloalkyl, (C1-C5) - alkylthio, (Ci-C5) haloalkylthio , Hydroxycarbonyl, (C 1 -C 5) -alkoxycarbonyl, (C 3 -C 6) -cycloalkoxycarbonyl, aryl- (C 1 -C 5) -alkoxycarbonyl, (C 2 -C 5) -alkenyloxycarbonyl, (C 2 -C 5) -alkynyloxycarbonyl, aminocarbonyl, (C 1 -C 5) -alkylaminocarbonyl, bis [(C 1 -C 5 ) -alkyl] aminocarbonyl, (C 1 -C 5) -alkyl [(C 1 -C 5) -alkyl] aminocarbonyl, (C 1 -C 5) -alkyl [(C 1 -C 5) -alkoxy] -aminocarbonyl, (C 2 -C 5) - Alkenylaminocarbonyl, (C 3 -C 6) -cycloalkylaminocarbonyl, arylaminocarbonyl,
Aryl-(Ci-C5)-alkylaminocarbonyl, Amino, (CrC5)-Aikylamino, (Ca-Cr,)- Cycloalkylamino, Bis-[(d-C5)-Alkyl]amino steht, Aryl- (Ci-C5) -alkylaminocarbonyl, amino, (CrC5) -alkylamino, (Ca-Cr,) -cycloalkylamino, bis - [(d-C5) -alkyl] -amino,
I m ganz Speziellen bevorzugt ist die erfindungsgemäße Verwendung von I m very special preferred is the inventive use of
Verbindungen der allgemeinen Formel (I), die durch die Formeln (la) bis (lo) beschrieben werden, Compounds of the general formula (I) which are described by the formulas (Ia) to (Io)
worin [X-Y] für die Gruppierung where [X-Y] is the grouping
[x-ΥΓ sieht, für die Gruppierungen Q-1 bis Q-6 [x-ΥΓ sees, for the groupings Q-1 to Q-6
Q-1 Q-2 Q-3  Q-1 Q-2 Q-3
Q-4 , Q-5 und Q-6 steht, wobei R13, R14, R15, R16, R17, R18, R19, R20, R23, R24, R25, R26, R28, R29, R30, R31, R32, R34, R35 und R36 sowie A1 bis A9 jeweils die Bedeutung gemäß der nachstehenden Definitionen haben und wobei der Pfeil für eine Bindung zur jeweiligen Gruppierung C-R6 in den vorgenannten Formeln (la) bis (lo) steht, Q-4, Q-5 and Q -6, wherein R 13 , R 14 , R 15 , R 16 , R 17 , R 18 , R 19 , R 20 , R 23 , R 24 , R 25 , R 26 , R 28 , R 29 , R 30 , R 31 , R 32 , R 34 , R 35 and R 36 and A 1 to A 9 are each as defined in the have the following definitions and wherein the arrow for a bond to the respective grouping CR 6 is in the abovementioned formulas (Ia) to (Io),
R5 für Hydroxy, Methoxy, Ethoxy, n-Propyloxy, Methylcarbonyloxy, R 5 is hydroxy, methoxy, ethoxy, n-propyloxy, methylcarbonyloxy,
Ethylcarbonyloxy, n-Propylcarbonyloxy, i-Propylcarbonyloxy, n- Butylcarbonyloxy, sec-Butylcarbonyloxy, tert.-Butylcarbonyloxy, n- Pentylcarbonyloxy, Phenylcarbonyloxy, p-CI-Phenylcarbonyloxy, p- Methylphenylcarbonyloxy, p-Trifluormethylphenylcarbonyloxy, p- Methoxyphenylcarbonyloxy, o-CI-Phenylcarbonyloxy, o- Methylphenylcarbonyloxy, o-Trifluormethylphenylcarbonyloxy, o- Methoxyphenylcarbonyloxy, 2-Pyridylcarbonyloxy, 3-Pyridylcarbonyloxy, 4- Pyridylcarbonyloxy, 6-Trifluormethyl-3-Pyridylcarbonyloxy, 4-Chlor-3- Pyridylcarbonyloxy, Cyclopropylcarbonyloxy, Cyclobutylcarbonyloxy,  Ethylcarbonyloxy, n-propylcarbonyloxy, i -propylcarbonyloxy, n-butylcarbonyloxy, sec-butylcarbonyloxy, tert -butylcarbonyloxy, n-pentylcarbonyloxy, phenylcarbonyloxy, p-CI-phenylcarbonyloxy, p-methylphenylcarbonyloxy, p-trifluoromethylphenylcarbonyloxy, p-methoxyphenylcarbonyloxy, o-CI Phenylcarbonyloxy, o-methylphenylcarbonyloxy, o-trifluoromethylphenylcarbonyloxy, o-methoxyphenylcarbonyloxy, 2-pyridylcarbonyloxy, 3-pyridylcarbonyloxy, 4-pyridylcarbonyloxy, 6-trifluoromethyl-3-pyridylcarbonyloxy, 4-chloro-3-pyridylcarbonyloxy, cyclopropylcarbonyloxy, cyclobutylcarbonyloxy,
Cyclopentylcarbonyloxy, Cyclohexylcarbonyloxy, Methoxycarbonyloxy,  Cyclopentylcarbonyloxy, cyclohexylcarbonyloxy, methoxycarbonyloxy,
Ethoxycarbonyloxy, Trimethylsilyloxy, Triethylsilyloxy, Triisopropylsilyloxy Dimethylphenylsilyloxy, tert.-Butyldimethylsilyloxy steht,  Ethoxycarbonyloxy, trimethylsilyloxy, triethylsilyloxy, triisopropylsilyloxy, dimethylphenylsilyloxy, tert-butyldimethylsilyloxy,
R6 für Fluor, Chlor, Brom, lod, Cyano, Cyanomethyl, Trifluormethyl, R 6 represents fluorine, chlorine, bromine, iodine, cyano, cyanomethyl, trifluoromethyl,
Pentafluorethyl, Difluormethyl, Nitro, Amino, Hydroxy, Hydroxymethyl,  Pentafluoroethyl, difluoromethyl, nitro, amino, hydroxy, hydroxymethyl,
Hydrothio, Thiocyanato, Isothiocyanato, Trifluormethylthio, Methylthio, Methyl, Ethyl, n-Propyl, iso-Propyl, n-Butyl, iso-Butyl, tert.-Butyl, Hydroxy, Methoxy, Ethoxy, iso-Propyloxy, n-Propyloxy, n-Butyloxy, sec-Butyloxy, tert.-Butyloxy, n- Pentyloxy, Benzyloxy, p-Chlorbenzyloxy, p-Methoxybenzyloxy, p- Fluorbenzyloxy, p-Methylbenzyloxy, Difluormethoxy, Trifluormethoxy, 2,2- Difluorethoxy, 2,2,2-Trifluorethoxy, Phenoxy, p-Chlorphenoxy, p- Methylphenoxy, p-Fluorphenoxy, p-Methoxyphenoxy, p-Trifluormethylphenoxy, p-Trifluormethoxyphenoxy, m-Chlorphenoxy, m-Methylphenoxy, m- Fluorphenoxy, m-Methoxyphenoxy, m-Trifluormethylphenoxy, m- Trifluormethoxyphenoxy, o-Chlorphenoxy, o-Methylphenoxy, o-Fluorphenoxy, o- Methoxyphenoxy, o-Trifluormethylphenoxy, o-Trifluormethoxyphenoxy, 2,4- Dichlorphenoxy, 3.5-Dichlorphenoxy, 3.4-Dichlorphenoxy, 2,5-Dichlorphenoxy, Cyclopropylmethyloxy, Hydroxycarbonyl, Methoxycarbonyl, Ethoxycarbonyl, n- Propyloxycarbonyl, iso-Propyloxycarbonyl, n-Butyloxycarbonyl, sec- Butyloxycarbonyl, iso-Butyloxycarbonyl, tert.-Butyloxycarbonyl, n- Pentyloxycarbonyl, neo-Pentyloxycarbonyl, n-Hexyloxycarbonyl, Hydrothio, thiocyanato, isothiocyanato, trifluoromethylthio, methylthio, methyl, ethyl, n-propyl, iso-propyl, n-butyl, iso-butyl, tert-butyl, hydroxy, methoxy, ethoxy, iso-propyloxy, n-propyloxy, n Butyloxy, sec-butyloxy, tert -butyloxy, n-pentyloxy, benzyloxy, p-chlorobenzyloxy, p-methoxybenzyloxy, p-fluorobenzyloxy, p-methylbenzyloxy, difluoromethoxy, trifluoromethoxy, 2,2-difluoroethoxy, 2,2,2- Trifluoroethoxy, phenoxy, p-chlorophenoxy, p-methylphenoxy, p-fluorophenoxy, p-methoxyphenoxy, p-trifluoromethylphenoxy, p-trifluoromethoxyphenoxy, m-chlorophenoxy, m-methylphenoxy, m-fluorophenoxy, m-methoxyphenoxy, m-trifluoromethylphenoxy, m- Trifluoromethoxyphenoxy, o-chlorophenoxy, o-methylphenoxy, o-fluorophenoxy, o-methoxyphenoxy, o-trifluoromethylphenoxy, o-trifluoromethoxyphenoxy, 2,4-dichlorophenoxy, 3,5-dichlorophenoxy, 3,4-dichlorophenoxy, 2,5-dichlorophenoxy, cyclopropylmethyloxy, hydroxycarbonyl, Methoxycarbonyl, ethoxycarbonyl, n-propyloxycarbonyl, iso-propyloxycarbonyl, n-butyloxycarbonyl, s ec-butyloxycarbonyl, iso-butyloxycarbonyl, tert-butyloxycarbonyl, n- Pentyloxycarbonyl, neo-pentyloxycarbonyl, n-hexyloxycarbonyl,
Benzyloxycarbonyl, p-Chlorbenzyloxycarbonyl, p-Methoxybenzyloxycarbonyl, p- Fluorbenzyloxycarbonyl, p-Methylbenzyloxycarbonyl, Allyloxycarbonyl, Benzyloxycarbonyl, p-chlorobenzyloxycarbonyl, p-methoxybenzyloxycarbonyl, p-fluorobenzyloxycarbonyl, p-methylbenzyloxycarbonyl, allyloxycarbonyl,
Methoxyethoxycarbonyl, Ethoxyethoxycarbonyl, Ethoxymethoxycarbonyl, Methoxy-n-propyloxycarbonyl, Ethoxy-n-propoxycarbonyl, Methoxyethoxycarbonyl, ethoxyethoxycarbonyl, ethoxymethoxycarbonyl, methoxy-n-propyloxycarbonyl, ethoxy-n-propoxycarbonyl,
Cyclopropyloxycarbonyl, Cyclobutyloxycarbonyl, Cyclopentyloxycarbonyl, Cyclohexyloxycarbonyl, (C2-C6)-alkinyloxycarbonyl, 2,2,-Difluorethoxycarbonyl, 2.2.2-Trifluorethoxycarbonyl, Methylaminocarbonyl, Ethylaminocarbonyl, n- Propylaminocarbonyl, iso-Propylaminocarbonyl, n-Butylaminocarbonyl, iso- Butylaminocarbonyl, tert.-Butylaminocarbonyl, n-Pentylaminocarbonyl, neo- Pentylaminocarbonyl, iso-Pentylaminocarbonyl, Cyclopropylaminocarbonyl, Cyclobutylaminocarbonyl, Cyclopentylaminocarbonyl, Cyclopropyloxycarbonyl, cyclobutyloxycarbonyl, cyclopentyloxycarbonyl, cyclohexyloxycarbonyl, (C 2 -C 6) -alkynyloxycarbonyl, 2,2'-difluoroethoxycarbonyl, 2,2,2-trifluoroethoxycarbonyl, methylaminocarbonyl, ethylaminocarbonyl, n -propylaminocarbonyl, iso -propylaminocarbonyl, n-butylaminocarbonyl, isobutylaminocarbonyl, tert -Butylaminocarbonyl, n-pentylaminocarbonyl, neopentylaminocarbonyl, isopentylaminocarbonyl, cyclopropylaminocarbonyl, cyclobutylaminocarbonyl, cyclopentylaminocarbonyl,
Cyclohexylaminocarbonyl, Piperidinyl-N-carbonyl, Pyrrolidinyl-N-carbonyl, Cyanomethylaminocarbonyl, Cyanoethylaminocarbonyl, Cyclohexylaminocarbonyl, piperidinyl-N-carbonyl, pyrrolidinyl-N-carbonyl, cyanomethylaminocarbonyl, cyanoethylaminocarbonyl,
Dimethylaminocarbonyl, Diethylaminocarbonyl, Ethyl(methyl)aminocarbonyl, Diisopropylaminocarbonyl, Methoxyethylaminocarbonyl, Dimethylaminocarbonyl, diethylaminocarbonyl, ethyl (methyl) aminocarbonyl, diisopropylaminocarbonyl, methoxyethylaminocarbonyl,
Ethoxyethylaminocarbonyi, (C2-C6)-alkinylaminocarbonyl, Methyisuifonylamino, Ethylsulfonylamino, iso-Propylsulfonylamino, Cyclopropylsulfonylamino, Phenylsulfonylamino, p-Chlorphenylsulfonylamino, o-Chlorphenylsulfonylamino, m-Chlorphenylsulfonylamino, p-Fluorphenylsulfonylamino, o- Fluorphenylsulfonylamino, m-Fluorphenylsulfonylamino, p- lodphenylsulfonylamino, o-lodphenylsulfonylamino, m- lodphenylsulfonylamino.p-Methoxyphenylsulfonylamino, o- Methoxyphenylsulfonylamino, m-Methoxyphenylsulfonylamino, p- Trifluormethylphenylsulfonylamino, o-Trifluormethylphenylsulfonylamino, m- Trifluormethylphenylsulfonylamino, p-Methylphenylsulfonylamino, o- Methylphenylsulfonylamino, m-Methylphenylsulfonylamino, Ethoxyethylaminocarbonyi, (C2-C6) -alkinylaminocarbonyl, Methyisuifonylamino, ethylsulfonylamino, iso-propylsulfonylamino, Cyclopropylsulfonylamino, phenylsulfonylamino, p-chlorophenylsulfonylamino, o-chlorophenylsulfonylamino, m-chlorophenylsulfonylamino, p-fluorophenylsulfonylamino, o- fluorophenylsulfonylamino, m-fluorophenylsulfonylamino, p-lodphenylsulfonylamino, o-iodophenylsulfonylamino, m-iodophenylsulfonylamino, p-methoxyphenylsulfonylamino, o-methoxyphenylsulfonylamino, m-methoxyphenylsulfonylamino, p-trifluoromethylphenylsulfonylamino, o-trifluoromethylphenylsulfonylamino, m-trifluoromethylphenylsulfonylamino, p-methylphenylsulfonylamino, o-methylphenylsulfonylamino, m-methylphenylsulfonylamino,
Methoxycarbonyiamino, Ethoxycarbonylamino, n-Propyloxycarbonylamino, iso- Propyloxycarbonylamino, tert.-Butyloxycarbonylamino, n- Butyloxycarbonylamino.Methylamino, Ethylamino, n-Propylamino, iso- Propylamino, Cyclopropylamino, Cyclobutylamino, Cyclopentylamino, Methoxycarbonyiamino, ethoxycarbonylamino, n-propyloxycarbonylamino, isopropyloxycarbonylamino, tert-butyloxycarbonylamino, n-butyloxycarbonylamino, methylamino, ethylamino, n-propylamino, iso-propylamino, cyclopropylamino, cyclobutylamino, cyclopentylamino,
Methylcarbonylamino, Ethylcarbonylamino, n-Propylcarbonylamino, iso- Propylcarbonylamino, n-Butylcarbonylamino, iso-Butylcarbonylamino, tert.- Butylcarbonylamino, Cyclopropycarbonylamino, Phenylcarbonylamino, Formyl, Methylcarbonyloxy, Ethylcarbonyloxy, n-Propylcarbonyloxy, iso- Propylcarbonyloxy, n-Butylcarbonyloxy, tert.-Butylcarbonyloxy, Methylcarbonylamino, ethylcarbonylamino, n-propylcarbonylamino, iso-propylcarbonylamino, n-butylcarbonylamino, iso-butylcarbonylamino, tert-butylcarbonylamino, cyclopropycarbonylamino, phenylcarbonylamino, formyl, Methylcarbonyloxy, ethylcarbonyloxy, n-propylcarbonyloxy, iso -propylcarbonyloxy, n-butylcarbonyloxy, tert-butylcarbonyloxy,
Cyclopropylcarbonyloxy, Cyclobutylcarbonyloxy, Cyclopentylcarbonyloxy, Cyclohexylcarbonyloxy, Aminosulfonyl, Methylaminosulfonyl, Cyclopropylcarbonyloxy, cyclobutylcarbonyloxy, cyclopentylcarbonyloxy, cyclohexylcarbonyloxy, aminosulfonyl, methylaminosulfonyl,
Ethylaminosulfonyl, n-Propylaminosulfonyl, iso-Propylaminosulfonyl, n- Butylaminosulfonyl, tert.-Butylaminosulfonyl, iso-Butylaminosulfonyl, Ethylaminosulfonyl, n-propylaminosulfonyl, iso-propylaminosulfonyl, n-butylaminosulfonyl, tert-butylaminosulfonyl, iso-butylaminosulfonyl,
Cyclopropylaminosulfonyl, Hydroxyiminomethyl, Methoxyiminomethyl, Cyclopropylaminosulfonyl, hydroxyiminomethyl, methoxyiminomethyl,
Ethoxyiminomethyl, n-Propyloxyiminomethyl, iso-Propyloxyiminomethyl, n- Butyloxyiminomethyl, iso-Butyloxyiminomethyl, tert.-Butyloxyiminomethyl, Cyclopropylmethoxyiminomethyl, (Ci-Cr>)-Alkoxycarbonyl-heterocyclyl-N- carbonyl, (Ci-Cö)-Alkoxycarbonyl-(Ci-C6)-alkyl-heterocyclylidenaminocarbonyl, (Ci-C6)-Alkoxycarbonylheterocyclyliden-(Ci-C6)-alkylaminocarbonyl, (Ci-Ce)- Alkoxycarbonyl-(Ci-C6)-Alkylaminocarbonyl, (Ci-C6)-Alkoxycarbonyl-(d-C6)- Alkyl((Ci-C6)-alkyl)aminocarbonyl, (CrC6)-Alkoxycarbonyl-(C:rC6)- cycloalkylidenaminocarbonyl, (CrCe AIkoxycarbonyKCa-Ce)- cycloalkylaminocarbonyl, Aminocarbonyl, (C3-C5)-Cycloalkyl-(d-C5)- alkoxycarbonyl, , (C2-C5)-Alkenyloxy-(CrC5)-alkoxycarbonyl, (C1-C5)- Alkylamino-(Ci-C5)-alkoxycarbonyl, Tris[(Ci-Crj)-alkyl]silyioxy-(Ci-C5)- alkoxy carbonyl, Bis[(Ci-C5)-Alkyl]amino-(Ci-Cr>)-alkoxycarbonyl, (C1-C5)- Alkyl[(Ci-C5)-alkyl]amino-(Ci-C5)-alkoxycarbonyl, Cyano-(Ci-Cs)- alkoxycarbonyl, Heterocyclyl-N-(CrCr>)-alkoxycarbonyl, Heteroaryloxycarbonyl, Heteroaryl-(Ci-Cr,)-alkoxycarbonyl, Heterocyclyl-(Ci-C5)-alkoxycarbonyl, Heterocyclyloxycarbonyl, (C2-C5)-Alkenyl-(d-C5)-alkoxycarbonyl, (C2-C5)- Alkinyl-(d-C5)-alkoxycarbonyl, Aryl-(C2-C5)-alkinyloxycarbonyl, Aryl-(C2-Cs)- alkenyloxycarbonyl, (Ci-C5)-Alkyl[(Ci-C5)-Alkoxy]aminocarbonyl, (C2-C5)- Alkenylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C5)-alkylaminocarbonyl, Heteroaryl-(Ci-C5)-alkylaminocarbonyl, (Ci-C5)-Haloalkylaminocarbonyl, (C2-C5)-Alkinyl-(Ci-C5)-alkylaminocarbonyl, (C1-C5)- Alkoxycarbonylaminocarbonyl, Aryl-(Ci-Cf))-alkoxycarbonylaminocarbonyl, Hydroxycarbonyl-(CrC5)-alkyl, (Ci-C5)-Alkoxycarbonyl-(Ci-C5)-alkyl, (C3-C6)- Cycloalkoxycarbonyl-(CrC5)-alkyl, (C3-C6)-Cycloalkyl-(Ci-Cr,)-alkoxycarbonyl- (Ci-C5)-alkyl, (C2-C5)-Alkenyloxycarbonyl-(Ci-C5)-alkyl, Aryl-(Ci-C5)- alkoxycarbonyl-(d-C5)-alkyl, (Ci-Cs)-Alkylaminocarbonyl-(Ci-C5)-alkyl, Aminocarbonyl-(Ci-C5)-alkyl, Bis[(Ci-C5)-alkyl]aminocarbonyl-(Ci-Cr,)-alkyl, (C3-C6)-Cycloalkylaminocarbonyl-(Ci-C5)-alkyl, Aryl-(Ci-C5)-alkylaminocarbonyl- (Ci-Cs)-alkyl, Heteroaryl-(CrC5)-alkylaminocarbonyl-(Ci-C5)-alkyl, Cyano- (Ci-C5)-alkylaminocarbonyl-(Ci-C5)-alkyl, (CrC5)-Haloalkylaminocarbonyl- (Ci-C5)-alkyl, (C2-C5)-Alkinyl-(Ci-C5)-alkylaminocarbonyl-(Ci-C5)-alkyl, (C3-C6)- Cycloalkyl-(Ci-C5)-alkylaminocarbonyl-(Ci-C5)-alkyl, (C1-C5)- Alkoxycarbonylaminocarbonyl-(CrC5)-alkyl, Aryl-(d-C5)- alkoxycarbonylaminocarbonyl-(Ci-C5)-alkyl, Hydroxycarbonyl-(Ci-C5)- alkylaminocarbonyl, Aryl-(Ci-C5)-alkoxycarbonyl-(Ci-C5)-alkylaminocarbonyl, Aminocarbonyl-(Ci-Crj)-alkylaminocarbonyl, (Ci-C5)-Alkylaminocarbonyl- (Ci-C5)-alkylaminocarbonyl, Ethoxyiminomethyl, n-Propyloxyiminomethyl, iso-Propyloxyiminomethyl, n- Butyloxyiminomethyl, iso-Butyloxyiminomethyl, tert-Butyloxyiminomethyl, Cyclopropylmethoxyiminomethyl, (Ci-Cr>) alkoxycarbonyl-heterocyclyl-N- carbonyl, (Ci-COE) alkoxycarbonyl (C -C 6) -alkyl-heterocyclylideneaminocarbonyl, (C 1 -C 6) -alkoxycarbonylheterocyclylido- (C 1 -C 6) -alkylaminocarbonyl, (C 1 -C 6) -alkoxycarbonyl- (C 1 -C 6) -alkylaminocarbonyl, (C 1 -C 6) -alkoxycarbonyl- (i.e. -C 6) - alkyl ((C 1 -C 6) -alkyl) aminocarbonyl, (C 1 -C 6) -alkoxycarbonyl- (C 1 -C 6) -cycloalkylideneaminocarbonyl, (C 1 -C 6 -alkoxycarbonyKCa-Ce) -cycloalkylaminocarbonyl, aminocarbonyl, (C 3 -C 5) -cycloalkyl- d-C5) alkoxycarbonyl, (C 2 -C 5) -alkenyloxy- (C 1 -C 5) -alkoxycarbonyl, (C 1 -C 5) -alkylamino- (C 1 -C 5) -alkoxycarbonyl, tris [(C 1 -C 6) -alkyl] silyioxy- (Ci-C5) - alkoxy carbonyl, bis [(Ci-C5) alkyl] amino- (Ci-Cr>) -alkoxycarbonyl, (C1-C5) - alkyl [(Ci-C5) alkyl] amino- (Ci C5) alkoxycarbonyl, cyano (Ci-Cs) - alkoxycarbonyl, heterocyclyl-N- (CrCr>) -alkoxycarbonyl, heteroaryloxy, Heteroaryl (C 1 -C 4) alkoxycarbonyl, heterocyclyl (C 1 -C 5) alkoxycarbonyl, heterocyclyloxycarbonyl, (C 2 -C 5) alkenyl (C 1 -C 5) alkoxycarbonyl, (C 2 -C 5) -alkynyl- (d-) C5) -alkoxycarbonyl, aryl- (C 2 -C 5) -alkynyloxycarbonyl, aryl- (C 2 -C 5) -alkenyloxycarbonyl, (C 1 -C 5) -alkyl [(C 1 -C 5) -alkoxy] -aminocarbonyl, (C 2 -C 5) -alkenylaminocarbonyl , Arylaminocarbonyl, aryl- (C 1 -C 5 ) -alkylaminocarbonyl, heteroaryl- (C 1 -C 5 ) -alkylaminocarbonyl, (C 1 -C 5 ) -haloalkylaminocarbonyl, (C 2 -C 5 ) -alkynyl- (C 1 -C 5 ) -alkylaminocarbonyl, (C1 -C5) - alkoxycarbonylaminocarbonyl, aryl- (Ci-Cf)) - alkoxycarbonylaminocarbonyl, hydroxycarbonyl- (CrC 5 ) -alkyl, (Ci-C 5 ) -alkoxycarbonyl- (Ci-C 5 ) -alkyl, (C 3 -C 6 ) - cycloalkoxycarbonyl (CRC5) alkyl, (C3-C6) cycloalkyl (Ci-Cr,) - alkoxycarbonyl (Ci-C 5) alkyl, (C2-C5) -Alkenyloxycarbonyl- (Ci-C 5 ) -alkyl, aryl- (C 1 -C 5 ) -alkoxycarbonyl- (C 1 -C 5 ) -alkyl, (C 1 -C 8) -alkylaminocarbonyl- (C 1 -C 5) -alkyl, aminocarbonyl- (C 1 -C 5) -alkyl, bis [(C-C5) alkyl] aminocarbonyl (C Cr) - alkyl, (C 3 -C 6) -cycloalkylaminocarbonyl- (C 1 -C 5) -alkyl, aryl- (C 1 -C 5) -alkylaminocarbonyl- (C 1 -C 8) -alkyl, heteroaryl- (C 1 -C 5) -alkylaminocarbonyl- (C 1 -C 5) -alkyl, Cyano- (C 1 -C 5 ) -alkylaminocarbonyl- (C 1 -C 5 ) -alkyl, (C 1 -C 5 ) -haloalkylaminocarbonyl- (C 1 -C 5 ) -alkyl, (C 2 -C 5 ) -alkynyl- (C 1 -C 5 ) -alkylaminocarbonyl- (Ci-C 5) alkyl, (C 3 -C 6) - cycloalkyl, (Ci-C 5) alkylaminocarbonyl (Ci-C 5) alkyl, (C1-C5) - Alkoxycarbonylaminocarbonyl- (CRC5) alkyl , Aryl- (C 1 -C 5) -alkoxycarbonylaminocarbonyl- (C 1 -C 5) -alkyl, hydroxycarbonyl- (C 1 -C 5) -alkylaminocarbonyl, aryl- (C 1 -C 5) -alkoxycarbonyl- (C 1 -C 5) -alkylaminocarbonyl, aminocarbonyl- C 1 -C 18) -alkylaminocarbonyl, (C 1 -C 5) -alkylaminocarbonyl- (C 1 -C 5) -alkylaminocarbonyl,
(C3-C6)-Cycloalkylaminocarbonyl-(Ci-C5)-alkylaminocarbonyl, (C3-C5)- Cycloalkyl-(Ci-C5)-alkylaminocarbonyl, (C3-C6)-Cycloalkyl-(Ci-C5)- alkylaminocarbonyl-(Ci-C5)-alkyl, (C3-C5)-Cycloalky!-(Ci-C6)- alkylaminocarbonyl-(Ci-C5)-alkylaminocarbonyl, (C2-C5)-Alkenyl-(d-C5)- alkylaminocarbonyl, (C2-C5)-Alkenylaminocarbonyl-(CrC5)-alkyl, (C2-C5)- Alkenyl-(Ci-C5)-alkylaminocarbonyl-(Ci-C5)-alkyl, (CrC5)-Alkylcarbonyl, (C3-C5)- Cycloalkylcarbonyl, Arylcarbonyl, Formyl, Hydroxyiminomethyl, (C 3 -C 6 ) -cycloalkylaminocarbonyl- (C 1 -C 5 ) -alkylaminocarbonyl, (C 3 -C 5 ) -cycloalkyl- (C 1 -C 5 ) -alkylaminocarbonyl, (C 3 -C 6 ) -cycloalkyl- (C 1 -C 5 ) -alkylaminocarbonyl (C 1 -C 5 ) -alkyl, (C 3 -C 5 ) -cycloalkyl- (C 1 -C 6 ) -alkylaminocarbonyl- (C 1 -C 5 ) -alkylaminocarbonyl, (C 2 -C 5 ) -alkenyl- (C 1 -C 5 ) alkylaminocarbonyl, (C 2 -C 5 ) -alkenylaminocarbonyl- (C 1 -C 5 ) -alkyl, (C 2 -C 5 ) -alkenyl- (C 1 -C 5 ) -alkylaminocarbonyl- (C 1 -C 5 ) -alkyl, (C 1 -C 5 ) -alkylcarbonyl, (C3-C5) - cycloalkylcarbonyl, arylcarbonyl, formyl, hydroxyiminomethyl,
Aminoiminomethyl, (Ci-C5)-Alkoxyiminomethyl, (Ci-C5)-Alkylaminoiminomethyl, Bis[(Ci-C5)-alkyl]aminoiminomethyl, (C3-C6)-Cycloalkoxyiminomethyl, (CS-CG)- Cycloalkyl-(Ci-Cr»)-alkoximinomethyl, Aryloximinomethyl, Aryl-(Ci-Cr>)- alkoxyiminomethyl, Aryl-(Ci-C5)-alkylaminoiminomethyl, (C2-C5)- Alkenyloxyiminomethyl, Arylaminoiminomethyl, Arylsulfonylaminoiminomethyl, Heteroaryl-(CrCr>)-alkyl, Heterocyclyl-(Ci-C5)-alkyl, Aminoiminomethyl, (Ci-C5) -alkoxyiminomethyl, (Ci-C5) -alkylaminoiminomethyl, bis [(Ci-C5) -alkyl] aminoiminomethyl, (C3-C6) -cycloalkoxyiminomethyl, (CS-CG) -cycloalkyl- (Ci-Cr ») -alkoximinomethyl, Aryloximinomethyl, aryl (Ci-Cr>) - alkoxyiminomethyl, aryl (Ci-C5) -alkylaminoiminomethyl, (C2-C5) - Alkenyloxyiminomethyl, Arylaminoiminomethyl, Arylsulfonylaminoiminomethyl, heteroaryl (CrCr>) alkyl, heterocyclic - (C 1 -C 5 ) -alkyl,
Hydroxycarbonylheterocyclyl, (CrC5)-Alkoxycarbonylheterocyclyl, (C2-C5)- Alkenyloxycarbonylheterocyclyl, (C2-C5)-Alkenyl-(d-C5)- alkoxycarbonylheterocyclyl, Aryl-(d-C5)-alkoxycarbonylheterocyclyl, (C3-C6)- Cycloalkoxycarbonylheterocyclyl, (C3-C5)-Cycloalkyl-(Ci-Cr>)- alkoxycarbonylheterocyclyl, Aminocarbonylheterocyclyl, (C1-C5)- Alkylaminocarbonylheterocyclyl, Bis[(Ci-C5)-Alkyl]aminocarbonylheterocyclyL (C3-C6)-Cycloalkylaminocarbonylheterocyclyl, Aryl-(Ci-Cs)- alkylaminocarbonylheterocyclyl, (C2-C5)-Alkenylaminocarbonylheterocyclyl, Hydroxycarbonylheterocyclyl-(CrCr>)-alkyl, (Ci-C5)-Alkoxycarbonylheterocyclyl- (Ci-C5)-alkyl, Hydroxycarbonyl-(C3-C6)-cycloalkyl-(Ci-C5)-alkyl, (C1-C5)- Alkoxycarbonyl-(C3-C5)-cycloalkyl-(Ci-C6)-alkyl, Hydroxyaminocarbonyl, (Ci-C5)-Alkoxyaminocarbonyl, Aryl-(Ci-C5)-alkoxyaminocarbonyl, Heterocyclyl steht, Hydroxycarbonylheterocyclyl, (C 1 -C 5) -alkoxycarbonyl-heterocyclyl, (C 2 -C 5) -alkenyloxycarbonyl-heterocyclyl, (C 2 -C 5) -alkenyl- (C 1 -C 5) -alkoxycarbonyl-heterocyclyl, aryl- (C 1 -C 5) -alkoxycarbonyl-heterocyclyl, (C 3 -C 6) -cycloalkoxycarbonyl-heterocyclyl, (C 3 -C 5) -cycloalkyl- (C 1 -C 8) -alkoxycarbonylheterocyclyl, aminocarbonyl-heterocyclyl, (C 1 -C 5) -alkylaminocarbonyl-heterocyclyl, bis [(C 1 -C 5) -alkyl] -aminocarbonyl-heterocyclyl (C 3 -C 6) -cycloalkylaminocarbonyl-heterocyclyl, aryl- (Ci -Cs) - alkylaminocarbonylheterocyclyl, (C2-C5) -Alkenylaminocarbonylheterocyclyl, Hydroxycarbonylheterocyclyl- (CrCr>) alkyl, (Ci-C5) -Alkoxycarbonylheterocyclyl- (Ci-C 5) alkyl, hydroxycarbonyl (C 3 -C 6) cycloalkyl (C 1 -C 5 ) -alkyl, (C 1 -C 5 ) -alkoxycarbonyl- (C 3 -C 5 ) -cycloalkyl- (C 1 -C 6) -alkyl, hydroxyaminocarbonyl, (C 1 -C 5) -alkoxyaminocarbonyl, aryl- (C 1 -C 5) -alkoxyaminocarbonyl, heterocyclyl,
R13, R14, R15 und R16 unabhängig voneinander für Wasserstoff, Fluor, Chlor, Brom, lod, Nitro, Amino, Cyano, Methyl, Ethyl, n-Propyl, iso-Propyl, n-Butyl, sec-Butyl, iso- Butyl, tert. Butyl, Cyclopropyl, Cyclobutyl, Cyclopentyl, Cyclohexyl, R 13 , R 14 , R 15 and R 16 independently of one another represent hydrogen, fluorine, chlorine, bromine, iodine, nitro, amino, cyano, methyl, ethyl, n-propyl, isopropyl, n-butyl, sec-butyl, iso-butyl, tert. Butyl, cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl,
gegebenenfalls substituiertes Phenyl, Heteroaryl, Hydroxy, Methoxy, Ethoxy, n- Propyloxy, iso-Propyloxy, n-Butyloxy, sec-Butyloxy, iso-Butyloxy, tert.-Butyloxy, Methoxyethoxy, Methoxymethoxy, Ethoxyethoxy, Ethoxymethoxy, Methoxy-n- propyloxy, Methoxymethyl, Ethoxymethyl, Methoxyethyl, Ethoxyethyl ,  optionally substituted phenyl, heteroaryl, hydroxy, methoxy, ethoxy, n-propyloxy, iso-propyloxy, n-butyloxy, sec-butyloxy, iso-butyloxy, tert-butyloxy, methoxyethoxy, methoxymethoxy, ethoxyethoxy, ethoxymethoxy, methoxy-n-propyloxy , Methoxymethyl, ethoxymethyl, methoxyethyl, ethoxyethyl,
Hydroxymethyl, Trifluormethoxy, Difiuormethoxy, 2,2-Difluorethoxy, 3,3.3- Trifluorethoxy, Trifluormethyl, Difluormethyl, 2,2-Difluorethyl, 3,3.3-Trifluorethyl, Hydrothio, Methylthio, Trifluormethylthio, Methylamino, Ethylamino,  Hydroxymethyl, trifluoromethoxy, difluoromethoxy, 2,2-difluoroethoxy, 3,3,3-trifluoroethoxy, trifluoromethyl, difluoromethyl, 2,2-difluoroethyl, 3,3,3-trifluoroethyl, hydrothio, methylthio, trifluoromethylthio, methylamino, ethylamino,
Dimethylamino, Diethylamino, Allylamino, Cyclopropylamino, Cyclobutylamino, Cyclopentylamino, Cyclohexylamino, Methylcarbonylamino,  Dimethylamino, diethylamino, allylamino, cyclopropylamino, cyclobutylamino, cyclopentylamino, cyclohexylamino, methylcarbonylamino,
Ethylcarbonylamino, n-Propylcarbonylamino, iso-Propylcarbonylamino, n- Butylcarbonylamino, iso-Butylcarbonylamino, tert.-Butylcarbonylamino,  Ethylcarbonylamino, n-propylcarbonylamino, iso -propylcarbonylamino, n-butylcarbonylamino, iso-butylcarbonylamino, tert-butylcarbonylamino,
Cyclopropylcarbonylamino, Cyclobutylcarbonylamino,  Cyclopropylcarbonylamino, cyclobutylcarbonylamino,
Cyclopentylcarbonylamino, Cyclohexylcarbonylamino, Arylcarbonylamino, Heteroarylcarbonylamino, Trifluormethylcarbonylamino, Methoxycarbonylamino, Ethoxycarbonylamino, Methylsulfonylamino, Ethylsulfonylamino, n- Propylsulfonylamino, Cyclopropylsulfonylamino, Cyclobutylsulfonylamino, Cyclopentylsulfonylamino, Cyclohexylsulfonylamino, Arylsulfonylamino,  Cyclopentylcarbonylamino, cyclohexylcarbonylamino, arylcarbonylamino, heteroarylcarbonylamino, trifluoromethylcarbonylamino, methoxycarbonylamino, ethoxycarbonylamino, methylsulfonylamino, ethylsulfonylamino, n-propylsulfonylamino, cyclopropylsulfonylamino, cyclobutylsulfonylamino, cyclopentylsulfonylamino, cyclohexylsulfonylamino, arylsulfonylamino,
Hetarylsulfonylamino, Hydroxy carbonyl, Methoxycarbonyl, Ethoxycarbonyl, n- Propyloxycarbonyl, iso-Propyloxycarbonyl, n-Butyloxycarbonyl, iso- Butyloxycarbonyl, tert.-Butyloxycarbonyl, Cyclopropyloxycarbonyl,  Hetarylsulfonylamino, hydroxy carbonyl, methoxycarbonyl, ethoxycarbonyl, n-propyloxycarbonyl, isopropyloxycarbonyl, n-butyloxycarbonyl, isobutoxycarbonyl, tert-butyloxycarbonyl, cyclopropyloxycarbonyl,
Cyclobutyloxycarbonyl, Cyclopentyloxycarbonyl, Cyclohexyloxycarbonyl, Cyclopropylmethoxycarbonyl, Cyclohexylmethoxy carbonyl, Aryloxycarbonyl, Benzyloxycarbonyl, p-Chlorbenzyloxycarbonyl, p-methoxybenzyloxycarbonyl, Allyloxycarbonyl, (C2-Cs)-Alkinyloxycarbonyl, Aminocarbonyl, (C1-C5)- Alkylaminocarbonyl, Bis[(Ci-C5)-alkyl]aminocarbonyl, (CrCr,)-Alkyl[(Ci-C5)- Alkyljaminocarbonyl, (Ci-C5)-Alkyl-[(CrC5)-Alkoxy]aminocarbonyl, (C2-C5)- Alkenylaminocarbonyl, (Ca-Cc -Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(d-C5)-alkylaminocarbonyl stehen, A\ A2, A3 und A4 gleich oder verschieden sind und unabhängig voneinander für NCyclobutyloxycarbonyl, cyclopentyloxycarbonyl, cyclohexyloxycarbonyl, cyclopropylmethoxycarbonyl, cyclohexylmethoxycarbonyl, aryloxycarbonyl, benzyloxycarbonyl, p-chlorobenzyloxycarbonyl, p-methoxybenzyloxycarbonyl, allyloxycarbonyl, (C 2 -C 5) -alkynyloxycarbonyl, aminocarbonyl, (C 1 -C 5) -alkylaminocarbonyl, bis [(C 1 -C 5) -alkyl] aminocarbonyl, (CrCr,) - alkyl [(Ci-C5) - alkyljaminocarbonyl, (Ci-C5) -alkyl - [(CrC5) alkoxy] aminocarbonyl, (C2-C5) - alkenylaminocarbonyl, (Ca-Cc - Cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 5) -alkylaminocarbonyl, A \ A 2 , A 3 and A 4 are the same or different and are independently N
(Stickstoff) oder die Gruppierungen C-H, C-CH3, C-F, C-Cl, C-Br. C-l, C-OCF3, C-OCH3, C-CF3, C-CO2H, C-CO2CH3 stehen, wobei jedoch in keinem Fall mehr als zwei N-Atome benachbart sind, (Nitrogen) or the groups CH, C-CH 3 , CF, C-Cl, C-Br. Cl, C-OCF3, C-OCH3, C-CF 3, C-CO2H, C-CO2CH3 are, but in no case more than two N atoms are adjacent,
R17 und R18 unabhängig voneinander für Wasserstoff, Fluor, Chlor, Brom, lod, Methyl, Ethyl, iso-Propyl, gegebenenfalls substituiertes Phenyl, Heteroaryl, R 17 and R 18 independently of one another represent hydrogen, fluorine, chlorine, bromine, iodine, methyl, ethyl, isopropyl, optionally substituted phenyl, heteroaryl,
Heterocyclyl, Cyclopropyl, Cyclobutyl, Cyclopentyl, Cyclohexyl, Trifluormethyl, Difluormethyl, Hydroxycarbonyl, Methoxycarbonyl, Ethoxycarbonyl, tert.- Butyloxycarbonyl, Benzyloxycarbonyl, Allyloxycarbonyl, Aminocarbonyl, Methylaminocarbonyl, Ethylaminocarbonyl, iso-Propylaminocarbonyl,  Heterocyclyl, cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, trifluoromethyl, difluoromethyl, hydroxycarbonyl, methoxycarbonyl, ethoxycarbonyl, tert-butyloxycarbonyl, benzyloxycarbonyl, allyloxycarbonyl, aminocarbonyl, methylaminocarbonyl, ethylaminocarbonyl, isopropylaminocarbonyl,
Dimethylaminocarbonyl, Allylaminocarbonyl, Cyclopropylaminocarbonyl, Cyclobutylaminocarbonyl, Cyclopentylaminocarbonyl,  Dimethylaminocarbonyl, allylaminocarbonyl, cyclopropylaminocarbonyl, cyclobutylaminocarbonyl, cyclopentylaminocarbonyl,
Cyclohexylaminocarbonyl, Benzylaminocarbonyl stehen,  Cyclohexylaminocarbonyl, benzylaminocarbonyl,
A5 für S (Schwefel), O (Sauerstoff) oder die Gruppierungen N-H, N-CH3, N-CH2CH3, N- CH(CH3)2, N-C02t-Bu, N-Aryl, N-Heteroaryl, N-Heterocyclyl steht, A 5 for S (sulfur), O (oxygen) or the groupings NH, N-CH 3 , N-CH 2 CH 3 , N-CH (CH 3 ) 2 , N-CO 2 t-Bu, N-aryl, N-heteroaryl , N-heterocyclyl,
R19, R2Ü, R23 und R24 unabhängig voneinander für Wasserstoff, Methyl, Ethyl, iso- Propyl, Fluor, Chlor, Brom, lod, Cyclopropyl, Cyclobutyl, Cyclopentyl, R 19 , R 2Ü , R 23 and R 24 are each independently hydrogen, methyl, ethyl, iso-propyl, fluorine, chlorine, bromine, iodine, cyclopropyl, cyclobutyl, cyclopentyl,
Cyclohexyl, gegebenenfalls substituiertes Phenyl, Heteroaryl, Heterocyclyl, Trifluormethyl, Difluormethyl stehen,  Cyclohexyl, optionally substituted phenyl, heteroaryl, heterocyclyl, trifluoromethyl, difluoromethyl,
R19 und R23 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 19 and R 23 with the atoms to which they are attached form a completely saturated or partially saturated, optionally further substituted 5 to 7-membered ring,
A6, A7 gleich oder verschieden sind und unabhängig voneinander für O (Sauerstoff), S (Schwefel), N-H, N-OCH3, N-CH3 oder die Gruppierung CR2 R22 stehen, wobei jedoch in keinem Fall zwei N-, O- oder S-Atome benachbart sind, und wobei R21 und R22 in der Gruppierung CR21R22 jeweils gleiche oder verschiedene A 6 , A 7 are identical or different and independently of one another represent O (oxygen), S (sulfur), NH, N-OCH 3, N-CH 3 or the group CR 2 R 22 , but in no case are two N , O or S atoms are adjacent, and wherein R 21 and R 22 in the group CR 21 R 22 are each the same or different
Bedeutungen gemäß der nachstehenden Definition haben und R21 und R22 unabhängig voneinander für Wasserstoff, Fluor, Chlor, Brom, lod, Methyl, Ethyl, is-Propyl, n-Propyl, gegebenenfalls substituiertes Phenyl, Heteroaryl, Heterocyclyl, Cyclopropyl, Cyclobutyl, Cyclopentyl, Cyclohexyl, Methoxy, Ethoxy, Trifluormethyl, Difluormethyl, Trifiuormethoxy, Methylthio, Have meanings as defined below and R 21 and R 22 independently of one another are hydrogen, fluorine, chlorine, bromine, iodine, methyl, ethyl, isopropyl, n-propyl, optionally substituted phenyl, heteroaryl, heterocyclyl, cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, methoxy, ethoxy, Trifluoromethyl, difluoromethyl, trifluoromethoxy, methylthio,
Trifluormethylthio, Hydroxycarbonyl, Methoxycarbonyl, Ethoxycarbonyl, n- Propyloxycarbonyl, iso-Propyloxycarbonyl, tert.-Butyloxycarbonyl,  Trifluoromethylthio, hydroxycarbonyl, methoxycarbonyl, ethoxycarbonyl, n-propyloxycarbonyl, isopropyloxycarbonyl, tert-butyloxycarbonyl,
Benzyloxycarbonyi, Cyclopropylmethoxycarbonyl, Allyloxycarbonyl,  Benzyloxycarbonyi, cyclopropylmethoxycarbonyl, allyloxycarbonyl,
Aminocarbonyl, Methylaminocarbonyl, Ethylaminocarbonyl, n- Propylaminocarbonyl, iso-Propylaminocarbonyl, Dimethylaminocarbonyl, Cyclopropylaminocarbonyl, Cyclobutylaminocarbonyl stehen,  Aminocarbonyl, methylaminocarbonyl, ethylaminocarbonyl, n-propylaminocarbonyl, iso-propylaminocarbonyl, dimethylaminocarbonyl, cyclopropylaminocarbonyl, cyclobutylaminocarbonyl,
R25, R26, R28 und R29 unabhängig voneinander für Wasserstoff, Methyl, Ethyl, n-Propyl, iso-Propyl, n-Butyl, tert.-Butyl, Cyclopropyl, Cyclobutyl, Cyclopentyl, Cyclohexyl, Fluor, Chlor, Brom, lod, gegebenenfalls substituiertes Phenyl, Heteroaryl, Heterocyclyl, Methoxy, Ethoxy, Trifluormethyl, Difluormethyl stehen, R 25 , R 26 , R 28 and R 29 independently of one another represent hydrogen, methyl, ethyl, n-propyl, isopropyl, n-butyl, tert-butyl, cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, fluorine, chlorine, bromine , iodine, optionally substituted phenyl, heteroaryl, heterocyclyl, methoxy, ethoxy, trifluoromethyl, difluoromethyl,
A8 für O (Sauerstoff), S (Schwefel), N-H, N-CH3, N-OCH3 oder die Gruppierung CHR27 steht und wobei R27 in der Gruppierung CHR27 die Bedeutung gemäß der nachstehenden Definition hat, A 8 is O (oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the moiety CHR 27 , and wherein R 27 in the moiety CHR 27 has the meaning as defined below,
R27 für Wasserstoff, Fluor, Chlor, Brom, lod, Methyl, Ethyl, is-Propyl, n-Propyl, R 27 is hydrogen, fluorine, chlorine, bromine, iodine, methyl, ethyl, isopropyl, n-propyl,
gegebenenfalls substituiertes Phenyl, Heteroaryl, Heterocyclyl, Cyclopropyl, Cyclobutyl, Cyclopentyl, Cyclohexyl, Methoxy, Ethoxy, Trifluormethyl,  optionally substituted phenyl, heteroaryl, heterocyclyl, cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, methoxy, ethoxy, trifluoromethyl,
Difluormethyl, Trifiuormethoxy, Difluormethoxy, Methylthio, Trifluormethylthio, Hydroxycarbonyl, Methoxycarbonyl, Ethoxycarbonyl, n-Propyloxycarbonyl, iso- Propyloxycarbonyl, tert.-Butyloxycarbonyl, Benzyloxycarbonyi, Allyloxycarbonyl, Aminocarbonyl, Methylaminocarbonyl, Ethylaminocarbonyl, n- Propylaminocarbonyl, iso-Propylaminocarbonyl, Dimethylaminocarbonyl, Cyclopropylaminocarbonyl, Cyclobutylaminocarbonyl steht,  Difluoromethyl, trifluoromethoxy, difluoromethoxy, methylthio, trifluoromethylthio, hydroxycarbonyl, methoxycarbonyl, ethoxycarbonyl, n -propyloxycarbonyl, iso -propyloxycarbonyl, tert-butyloxycarbonyl, benzyloxycarbonyi, allyloxycarbonyl, aminocarbonyl, methylaminocarbonyl, ethylaminocarbonyl, n -propylaminocarbonyl, isopropylaminocarbonyl, dimethylaminocarbonyl, cyclopropylaminocarbonyl , Cyclobutylaminocarbonyl,
R30, R31, R32, R34, R35 und R36 unabhängig voneinander für Wasserstoff, Methyl, Ethyl, n-Propyl, iso-Propyl, Fluor, Chlor, Brom, lod, Cyclopropyl, gegebenenfalls substituiertes Phenyl, Heteroaryl, Heterocyclyl, Methoxy, Ethoxy, n-Propyloxy, iso-Propyloxy, Trifluormethyl, Difluormethyl, Methylthio, Trifluormethylthio stehen, R 30 , R 31 , R 32 , R 34 , R 35 and R 36 independently of one another are hydrogen, methyl, ethyl, n-propyl, isopropyl, fluorine, chlorine, bromine, iodine, cyclopropyl, optionally substituted phenyl, heteroaryl, Heterocyclyl, methoxy, ethoxy, n-propyloxy, iso-propyloxy, trifluoromethyl, difluoromethyl, methylthio, trifluoromethylthio,
A9 für O (Sauerstoff), S (Schwefel), N-H, N-CH3, N-OCH3 oder die Gruppierung CHR steht und wobei R33 in der Gruppierung CHR33 die Bedeutung gemäß der nachstehenden Definition hat und A 9 is O (oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the group CHR and wherein R 33 in the group CHR 33 has the meaning as defined below, and
R33 für Wasserstoff, Fluor, Chlor, Brom, lod, Methyl, Ethyl, is-Propyl, n-Propyl, R 33 is hydrogen, fluorine, chlorine, bromine, iodine, methyl, ethyl, isopropyl, n-propyl,
gegebenenfalls substituiertes Phenyl, Heteroaryl, Heterocyclyl, Cyclopropyl, Cyclobutyl, Cyclopentyl, Cyclohexyl, Methoxy, Ethoxy, Trifluormethyl,  optionally substituted phenyl, heteroaryl, heterocyclyl, cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, methoxy, ethoxy, trifluoromethyl,
Difluormethyl, Trifluormethoxy, Difluormethoxy, Methylthio, Trifluormethylthio, Hydroxycarbonyl, Methoxycarbonyl, Ethoxycarbonyl, n-Propyloxycarbonyl, iso- Propyloxycarbonyl, tert.-Butyloxycarbonyl, Benzyloxycarbonyl, Allyloxycarbonyl, Aminocarbonyl, Methylaminocarbonyl, Ethylaminocarbonyl, n- Propylaminocarbonyl, iso-Propylaminocarbonyl, Dimethylaminocarbonyl, Difluoromethyl, trifluoromethoxy, difluoromethoxy, methylthio, trifluoromethylthio, hydroxycarbonyl, methoxycarbonyl, ethoxycarbonyl, n-propyloxycarbonyl, isopropyloxycarbonyl, tert-butyloxycarbonyl, benzyloxycarbonyl, allyloxycarbonyl, aminocarbonyl, methylaminocarbonyl, ethylaminocarbonyl, n-propylaminocarbonyl, isopropylaminocarbonyl, dimethylaminocarbonyl,
Cyclopropylaminocarbonyl, Cyclobutylaminocarbonyl steht. Cyclopropylaminocarbonyl, cyclobutylaminocarbonyl.
Die oben aufgeführten allgemeinen oder in Vorzugsbereichen aufgeführten The general or preferred ones listed above
Restedefinitionen gelten sowohl für die Endprodukte der allgemeinen Formel (I) als auch entsprechend für die jeweils zur Herstellung benötigten Ausgangs- oder Residue definitions apply both to the end products of the general formula (I) and correspondingly to the starting material or preparation required in each case for the preparation
Zwischenprodukte. Diese Restedefinitionen können untereinander, also auch zwischen den angegebenen bevorzugten Bereichen beliebig kombiniert werden. Intermediates. These remainder definitions can be combined with one another as desired, ie also between the specified preferred ranges.
Im Wesentlichen sind die zuvor genannten substituierten 1 -(Aryiethinyl)-, 1 - (Heteroarylethinyl)-, 1 -(Heterocyciyiethinyl)- und 1 -(Cyloalkenylethinyl)-bicycloalkanole der allgemeinen Formel (I) ebenfalls noch nicht im Stand der Technik bekannt. Somit gelten als weiterer Teil der Erfindung 1 -(Aryiethinyl)-, 1 -(Heteroarylethinyl)-, 1 - (Heterocyclylethinyl)- und 1-(Cyloalkenylethinyl)-bicycloalkanole der allgemeinen Formel (I), oder deren Salze In essence, the abovementioned substituted 1 - (aryiethynyl) -, 1 - (heteroarylethynyl) -, 1 - (Heterocyciyiethinyl) - and 1 - (Cyloalkenylethinyl) bicycloalkanols of the general formula (I) are also not yet known in the art. Thus, as a further part of the invention are 1 - (Aryiethinyl) -, 1- (heteroarylethynyl) -, 1- (heterocyclylethynyl) - and 1- (cycloalkenylethynyl) bicycloalkanols of the general formula (I), or salts thereof
wori Wori
[X-Y] für die Gruppierung [X-Y] for grouping
[x-YT steht, [x-YT stands,
Q für die Gruppierungen Q-1 bis Q-6 Q for the groupings Q-1 to Q-6
Q-1 Q-2 Q-3  Q-1 Q-2 Q-3
Q-4 i Q-5 und Q-6 steht, wobei R13, R14, R15, R16, R17, R18, R19, R20, R23, R24, R25, R26, R28, R29, R30, R31, R32, R34, R35 und R36 sowie A1 bis A9 jeweils die Bedeutung gemäß der nachstehenden Definitionen haben und wobei der Pfeil für eine Bindung zur jeweiligen Gruppierung C-R6 in der allgemeinen Formel (I) steht, Q-4 i Q-5 and Q-6 wherein R 13 , R 14 , R 15 , R 16 , R 17 , R 18 , R 19 , R 20 , R 23 , R 24 , R 25 , R 26 , R 28 , R 29 , R 30 , R 31 , R 32 , R 34 , R 35 and R 36 and A 1 to A 9 each have the meaning according to the definitions below and wherein the arrow for a bond to the respective group CR 6 in the general formula (I),
R1 für (Ci-C7)-Alkyl, (C3-C7)-Cycloalkyl, (C4-C7)-Cycloalkenyl, (C2-C7)-Alkenyl, (C2-C7)-Alkinyl. (C2-C7)-Alkenyl-(Ci-C7)-alkyl, (C2-C7)-Alkinyl-(Ci-C7)-alkyl, R 1 is (Ci-C7) alkyl, (C 3 -C 7) cycloalkyl, (C 4 -C 7) cycloalkenyl, (C2-C7) alkenyl, (C 2 -C 7) alkynyl , (C 2 -C 7) alkenyl (Ci-C7) alkyl, (C 2 -C 7) alkynyl (Ci-C7) alkyl,
(Ci-C7)-Alkoxy-(Ci-C7)-alkyl, Hydroxy-(Ci-C7)-alkyl, (C,-C7)-Haloalkyl, (C2-C7)- Haloalkenyl, (C2-C7)-Haloalkinyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-alkyl, (C1-C7)- Alkoxy-(Ci-C7)-haloalkyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-haloalkyl, (C1-C7)- Alkylthio-(d-C7)-alkyl, (Ci-C7)-Haloalkylthio-(CrC7)-alkyl steht, (Ci-C7) alkoxy (Ci-C7) alkyl, hydroxy (Ci-C7) alkyl, (C, -C 7) haloalkyl, (C2-C7) - haloalkenyl, (C 2 -C 7) haloalkynyl, (Ci-C7) haloalkoxy (Ci-C7) alkyl, (C1-C7) - Alkoxy (Ci-C7) haloalkyl, (Ci-C7) haloalkoxy (Ci-C7) haloalkyl, (C1-C7) - alkylthio (dC 7) alkyl, (Ci-C 7) Haloalkylthio (C 1 -C 7 ) -alkyl,
I3 und R4 unabhängig voneinander für Wasserstoff, Halogen, (d-C7)-Alkyl, I 3 and R 4 independently of one another represent hydrogen, halogen, (C 1 -C 7 ) -alkyl,
(C3-C7)-Cycloalkyl, (C4-C7)-Cycloalkenyl, (C2-C7)-Alkenyl, (C2-C7)-Alkinyl, (C2-C7)-Alkenyl-(CrC7)-alkyl, (C2-C7)-Alkinyl-(Ci-C7)-a!kyl, (Ci-C7)-Alkoxy- (Ci-C7)-alkyl, Hydroxy-(Ci-C7)-alkyl, (Ci-C7)-Haloa!kyl, (C2-C7)-Haloalkenyl, (C2-C7)-Haloalkinyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-alkyl, (Ci-C7)-Alkoxy-(Ci-C7)- haloalkyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-haloalkyl, (Ci-C7)-Alkylthio-(Ci-C7)-alkyl, (Ci-C7)-Haloalkylthio-(Ci-C7)-alkyl stehen, für Hydroxy, (d-C7)-Alkoxy, Aryloxy, (C3-C7)-Cycloalkyloxy, (C2-C7)-Alkenyloxy, (C2-C7)-Alkenyl-(Ci-C7)-alkyloxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkyloxy, (C1-C7)- Alkylcarbonyloxy, Arylcarbonyloxy, Heteroarylcarbonyloxy, (C3-C )- Cycloalkylcarbonyloxy, (Ci-C7)-Alkoxycarbonyloxy, (C2-C7)- Alkenyloxycarbonyloxy, Aryloxy-(d-C7)-alkyloxy, Aryl-(d-C7)-alkyloxy, (d-C )- Alkoxy-(Ci-C7)-alkoxy-(d-C7)-alkyloxy, (Ci-C7)-Alkylthio-(CrC7)-alkyloxy, Tris[(Ci-C7)-alkyl]silyloxy, (Ci-C7)-Alkyl-Bis[(Ci-C7)-alkyl]silyloxy, (Ci-C7)-Alkyl- bis(Aryl)silyloxy, Aryl-bis[(Ci-C7)— alkyl]silyloxy, Cycloalkyl-bis[(Ci-C7)- alkyl]silyloxy, Halo-bis[(Ci-C7)-alkyl]silyloxy, Tris[(Ci-C7)-alkyl]silyl-(Ci-C7)- alkoxy-(d-C7)-alkyloxy, steht, für (Ci-C )-Alkylsulfonylaminocarbonyl, (C3-C7)-Cycloalkylsulfonyl- aminocarbonyl, Hydroxycarbonyl, (C 1 -C7)- AI koxyca rbony I , (C3-C7)- Cycloalkoxycarbonyl, (C3-C7)-Cycloalkyl-(CrC7)-alkoxycarbonyl, (C 3 -C 7 ) -cycloalkyl, (C 4 -C 7 ) -cycloalkenyl, (C 2 -C 7 ) -alkenyl, (C 2 -C 7 ) -alkynyl, (C 2 -C 7 ) -alkenyl- ( -C 7) alkyl, (C 2 -C 7) alkynyl (C 7) -a! kyl, (Ci-C7) alkoxy (Ci-C7) alkyl, hydroxy (Ci- C 7) alkyl, (Ci-C 7) -Haloa! kyl, (C 2 -C 7) haloalkenyl, (C 2 -C 7) haloalkynyl, (Ci-C7) haloalkoxy (Ci-C 7) alkyl, (Ci-C7) alkoxy (Ci-C7) - haloalkyl, (Ci-C7) haloalkoxy (Ci-C7) haloalkyl, (Ci-C7) -alkylthio (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -haloalkylthio (C 1 -C 7 ) -alkyl, for hydroxy, (C 1 -C 7 ) -alkoxy, aryloxy, (C 3 -C 7 ) -cycloalkyloxy, ( C 2 -C 7) alkenyloxy, (C 2 -C 7) alkenyl (Ci-C7) alkyloxy, (Ci-C7) alkoxy (Ci-C7) alkyloxy, (C1-C7 ) - alkylcarbonyloxy, arylcarbonyloxy, heteroarylcarbonyloxy, (C3-C) - cycloalkylcarbonyloxy, (Ci-C7) alkoxycarbonyloxy, (C2-C7) - Alkenyloxycarbonyloxy, aryloxy (dC 7) alkyloxy, aryl (dC 7) alkyloxy , (dC) - alkoxy- (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -alkyloxy, (C 1 -C 7 ) -alkylthio (C 1 -C 7 ) -alkyloxy, tris [(C 1 -C 7 ) -alkyl] silyloxy, (Ci-C 7 ) Alkyl bis [(C 1 -C 7 ) alkyl] silyloxy, (C 1 -C 7 ) alkyl bis (aryl) silyloxy, aryl bis [(C 1 -C 7 ) alkyl] silyloxy, cycloalkyl bis [ (C 1 -C 7 ) alkyl] silyloxy, halo-bis [(C 1 -C 7 ) alkyl] silyloxy, tris [(C 1 -C 7 ) alkyl] silyl (C 1 -C 7 ) alkoxy (dC 7) alkyloxy, stands for (C) -Alkylsulfonylaminocarbonyl, (C3-C 7) -Cycloalkylsulfonyl- aminocarbonyl, hydroxycarbonyl, (C 1 -C 7) - AI koxyca rbony I, (C3-C7) - cycloalkoxycarbonyl , (C 3 -C 7 ) -cycloalkyl- (C 1 -C 7 ) -alkoxycarbonyl,
Aryloxycarbonyl, Aryl-(d-C7)-alkoxycarbonyl, (C2-C7)-Alkenyloxycarbonyl, (C2-C7)-Alkinyloxycarbonyl, (Ci-C7)-Haloalkyloxycarbonyl, (Ci-C7)-Alkoxy- (Ci-C7)-alkoxycarbonyl, (C2-C7)-Alkenyloxy-(Ci-C7)-alkoxycarbonyl, (C1-C7)- Alkylamino-(Ci-C7)-alkoxycarbonyl, Tris[(Ci-C7)-alkyl]silyloxy-(Ci-C7)- a I koxyca rbony I, Bis[(Ci-C7)-Alkyl]amino-(Ci-C7)-alkoxycarbonyl, (d-C7)- Alkyl[(Ci-C7)-alkyl]amino-(CrC7)-alkoxycarbonyl, Cyano-(Ci-C7)- alkoxycarbonyl, Heterocyclyl-N-(Ci-C7)-alkoxycarbonyl, Heteroaryloxycarbonyl, Heteroaryl-(d-C )-alkoxycarbonyl, Heterocyclyl-(CrC7)-alkoxycarbonyl, Heterocyclyloxycarbonyl, (C2-C7)-Alkenyl-(Ci-C7)-alkoxycarbonyl, (C2-C7)- Alkinyl-(Ci-C-7)-alkoxycarbonyl, Aryl-(C2-C-7)-alkinyloxycarbonyl, Aryl-(C-2-C-7)- alkenyloxycarbonyl, Aminocarbonyl, (CrC7)-Alkylaminocarbonyl, Bis[(d-C7)- alkyljaminocarbonyl, (Ci-C7)-Alkyl[(Ci-C7)-Alkyl]aminocarbonyl, (C1-C7)- Alkyl[(Ci-C7)-Alkoxy]aminocarbonyl, (C2-C7)-Alkenylaminocarbonyl, (C3-C7)- Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C7)-alkylaminocarbonyl, Heteroaryl-(Ci-C7)-alkylaminocarbonyl, Cyano-(Ci-C7)-alkylaminocarbonyl, (Ci-C7)-Haloalkylaminocarbonyl, (C2-C7)-Alkinyl-(Ci-C7)-alkylaminocarbonyl, (Ci-C7)-Alkoxycarbonylaminocarbonyl, Aryl-(d-C7)-alkoxycarbonyl- aminocarbonyl, Hydroxycarbonyl-(Ci-C7)-alkyl, (Ci-C7)-Alkoxycarbonyl-(Ci-C7)- alkyl, (C3-C7)-Cycloalkoxycarbonyl-(Ci-C7)-alkyl, (C3-C7)-Cycloalkyi-(Ci-C7)- alkoxycarbonyl-(d-C7)-alkyl, (C2-C7)-Alkenyloxycarbonyl-(d-C7)-alkyl, Aryl- (Ci-C7)-alkoxycarbonyl-(CrC7)-alkyl, (Ci-C7)-Alkylaminocarbonyl-(Ci-C7)-alkyl, Aminocarbonyl-(Ci-C7)-alkyl, Bis[(Ci-C7)-alkyl]aminocarbonyl-(Ci-C7)-alkyl, (C3-C7)-Cycloalkylaminocarbonyl-(Ci-C7)-alkyl, Aryl-(CrC7)-alkylaminocarbonyl- (Ci-C7)-alkyl, Heteroaryl-(Ci-C7)-alkylaminocarbonyl-(Ci-C7)-alkyl, Cyano- (CrC7)-alkylaminocarbonyl-(Ci-C7)-alkyl, (CrC7)-Haloalkylaminocarbonyl- (Ci-C7)-alkyl, (C2-C7)-Alkinyl-(Ci-C7)-alkylaminocarbonyl-(Ci-C7)-alkyl, (C3-C7)- Cycloalkyl-(Ci-C7)-alkylaminocarbonyl-(Ci-C7)-alkyl, (C1-C7)- Alkoxycarbonylaminocarbonyl-(Ci-C7)-alkyl, Aryl-(Ci-C7)-alkoxycarbonyl- aminocarbonyl-(Ci-C7)-alkyl, (Ci-C7)-Alkoxycarbonyl-(Ci-C7)- alkylaminocarbonyl, Hydroxycarbonyl-(Ci-C7)-alkylaminocarbonyl, Aryl-(d-C7)- alkoxycarbonyl-(Ci-C7)-alkylaminocarbonyl, Aminocarbonyl-(CrC7)- alkylaminocarbonyl, (Ci-C7)-Alkylaminocarbonyl-(Ci-C7)-alkylaminocarbonyl, (C3-C7)-Cycloalkylaminocarbonyl-(Ci-C7)-alkylaminocarbonyl, (C3-C7)- Cycloalkyl-(Ci-C7)-alkylaminocarbonyl, (C3-C7)-Cycloalkyl-(Ci-C7)- alkylaminocarbonyl-(Ci-C7)-alkyl, (C3-C7)-Cycloalkyl-(Ci-C7)-alkyl- aminocarbonyl-(Ci-C7)-alkylaminocarbonyl, (C2-C7)-Alkenyl-(Ci-C7)- alkylaminocarbonyl, (C2-C7)-Alkenylaminocarbonyl-(Ci-C7)-alkyl, (C2-C7)- Alkenyl-(Ci-C7)-alkylaminocarbonyl-(Ci-C7)-alkyl, (Ci-C7)-Alkylcarbonyl. (C3-C7)- Cycloalkylcarbonyl, Arylcarbonyl, Formyl, Hydroxyiminomethyl, Aryloxycarbonyl, aryl (dC 7) -alkoxycarbonyl, (C 2 -C 7) alkenyloxycarbonyl, (C 2 -C 7) -alkynyloxycarbonyl, (C 7) -Haloalkyloxycarbonyl, (Ci-C7) alkoxy ( Ci-C 7) alkoxycarbonyl, (C 2 -C 7) alkenyloxy (Ci-C7) -alkoxycarbonyl, (C1-C7) - alkylamino (Ci-C7) -alkoxycarbonyl, tris [(Ci-C 7) alkyl] silyloxy (C 7) - a I koxyca rbony I, bis [(Ci-C 7) alkyl] amino- (Ci-C 7) alkoxycarbonyl, (dC 7) - alkyl [( C 1 -C 7 ) -alkyl] amino- (C 1 -C 7 ) -alkoxycarbonyl, cyano- (C 1 -C 7 ) -alkoxycarbonyl, heterocyclyl-N- (C 1 -C 7 ) -alkoxycarbonyl, heteroaryloxycarbonyl, heteroaryl- (C 1 -C 4) -alkoxycarbonyl , Heterocyclyl (C 1 -C 4 ) -alkoxycarbonyl, heterocyclyloxycarbonyl, (C 2 -C 7 ) -alkenyl- (C 1 -C 7 ) -alkoxycarbonyl, (C 2 -C 7 ) - Alkynyl- (C 1 -C 7) alkoxycarbonyl, aryl- (C 2 -C 7) alkynyloxycarbonyl, aryl- (C-2-C-7) alkenyloxycarbonyl, aminocarbonyl, (C 1 -C 7) -alkylaminocarbonyl, bis [(d -C 7) - alkyljaminocarbonyl, (C 1 -C 7) -alkyl [(C 1 -C 7) -alkyl] aminocarbonyl, (C 1 -C 7) -alkyl [(C 1 -C 7) -alkoxy] aminocarbonyl, (C 2 -C 7) -alkenylaminocarbonyl, (C 3 -C 7) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 7) -alkylaminocarbonyl, heteroaryl- (C 1 -C 7) -alkylaminocarbonyl, cyano- (C 1 -C 7) -alkylaminocarbonyl, (C 1 -C 7) -haloalkylaminocarbonyl, (C2 -C 7) alkynyl (C 1 -C 7) -alkylaminocarbonyl, (C 1 -C 7) -alkoxycarbonylaminocarbonyl, aryl- (C 1 -C 7) -alkoxycarbonylaminocarbonyl, hydroxycarbonyl- (C 1 -C 7) -alkyl, (C 1 -C 7) - Alkoxycarbonyl- (C 1 -C 7 ) -alkyl, (C 3 -C 7 ) -cycloalkoxycarbonyl- (C 1 -C 7 ) -alkyl, (C 3 -C 7 ) -cycloalkyi (C 1 -C 7 ) -alkoxycarbonyl- (C 1 -C 7) - alkyl, (C 2 -C 7) -alkenyloxycarbonyl- (C 1 -C 7) -alkyl, aryl- (C 1 -C 7) -alkoxycarbonyl- (C 1 -C 7) -alkyl, (C 1 -C 7) -alkylaminocarbonyl- (C 1 -C 7) -alkyl, Aminocarbonyl- (C 1 -C 7) -alkyl, bis [(C 1 -C 7) -alkyl] aminocarbonyl- (C 1 -C 7) -alkyl, (C 3 -C 7) -cyclo alkylaminocarbonyl- (C 1 -C 7) -alkyl, aryl- (C 1 -C 7) -alkylaminocarbonyl- (C 1 -C 7) -alkyl, heteroaryl- (C 1 -C 7) -alkylaminocarbonyl- (C 1 -C 7) -alkyl, cyano- (C 1 -C 7) -alkyl alkylaminocarbonyl- (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -haloalkylaminocarbonyl- (C 1 -C 7 ) -alkyl, (C 2 -C 7 ) -alkynyl- (C 1 -C 7 ) -alkylaminocarbonyl- (C 1 -C 7 ) -alkyl, (C 3 -C 7) -cycloalkyl- (C 1 -C 7) -alkylaminocarbonyl- (C 1 -C 7) -alkyl, (C 1 -C 7) -alkoxycarbonylaminocarbonyl- (C 1 -C 7) -alkyl, aryl- (C 1 -C 7) -alkoxycarbonyl- aminocarbonyl- (C 1 -C 7) -alkyl, (C 1 -C 7) -alkoxycarbonyl- (C 1 -C 7) -alkylaminocarbonyl, hydroxycarbonyl- (C 1 -C 7) -alkylaminocarbonyl, aryl- (C 1 -C 7) -alkoxycarbonyl- (C 1 -C 7) ) -alkylaminocarbonyl, aminocarbonyl- (C 1 -C 7) -alkylaminocarbonyl, (C 1 -C 7) -alkylaminocarbonyl- (C 1 -C 7) -alkylaminocarbonyl, (C 3 -C 7) -cycloalkylaminocarbonyl- (C 1 -C 7) -alkylaminocarbonyl, (C 3 -C 7) - cycloalkyl- (Ci-C7) -alkylaminocarbonyl, (C3-C7) -cycloalkyl- (Ci-C 7) - alkylaminocarbonyl (Ci-C7) alkyl, (C 3 -C 7) -cycloalkyl- (C -C 7) -alkylaminocarbonyl- (C 1 -C 7) -alkylaminocarbonyl, (C 2 -C 7) -alkenyl- (C 1 -C 7) -alkyl minocarbonyl, (C 2 -C 7 ) -alkenylaminocarbonyl- (C 1 -C 7 ) -alkyl, (C 2 -C 7 ) -alkenyl- (C 1 -C 7 ) -alkylaminocarbonyl- (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) - alkylcarbonyl. (C3-C7) - cycloalkylcarbonyl, arylcarbonyl, formyl, hydroxyiminomethyl,
Aminoiminomethyl, (Ci-C7)-Alkoxyiminomethyl, (Ci-C7)-Alkylaminoiminomethyl, Bis[(Ci-C7)-alkyl]aminoiminomethyl, (C3-C7)-Cycloalkoxyiminomethyl, (C3-C7)- Cycloalkyl-(Ci-C7)-alkoximinomethyl, Aryloximinomethyl, Aryl-(d-C7)- alkoxyiminomethyL Aryl-(Ci-C7)-alkylaminoiminomethyL (C2-C7)- Alkenyloxyiminomethyl, Arylaminoiminomethyl, Arylsulfonylaminoiminomethyl, Hydroxycarbonylheterocyclyl-(CrC7)-alkyl, (CrC7)-Alkoxycarbonylheterocyclyl- (Ci-C7)-alkyl, Hydroxycarbonyl-(C3-C7)-cycloalkyl-(Ci-C7)-alkyl, (C1-C7)- Alkoxycarbonyl-(C3-C7)-cycloalkyl-(CrC7)-alkyl, Hydroxyaminocarbonyl, Aminoiminomethyl, (C 1 -C 7) -alkoxyiminomethyl, (C 1 -C 7) -alkylaminoiminomethyl, bis [(C 1 -C 7) -alkyl] aminoiminomethyl, (C 3 -C 7) -cycloalkoxyiminomethyl, (C 3 -C 7) -cycloalkyl- C7) -alkoximinomethyl, aryloximinomethyl, aryl- (d-C7) -alkoxyiminomethyl, aryl- (Ci-C7) -alkylaminoiminomethyl (C2-C7) - Alkenyloxyiminomethyl, Arylaminoiminomethyl, Arylsulfonylaminoiminomethyl, Hydroxycarbonylheterocyclyl- (CRC7) alkyl, (CRC7) -Alkoxycarbonylheterocyclyl- (Ci-C 7) alkyl, hydroxycarbonyl (C 3 -C 7) cycloalkyl- (Ci-C7) alkyl, ( C 1 -C 7 ) - alkoxycarbonyl- (C 3 -C 7 ) -cycloalkyl- (C 1 -C 7 ) -alkyl, hydroxyaminocarbonyl,
(CrC7)-Alkoxyaminocarbonyl, Aryl-(Ci-C7)-alkoxyaminocarbonyl, (d-Ce)-(CrC 7 ) -alkoxyaminocarbonyl, aryl- (C 1 -C 7 ) -alkoxyaminocarbonyl, (d-Ce) -
Alkoxycarbonyl-heterocyclyl-N-carbonyl, (Ci-C6)-Alkoxycarbonyl-(Ci-C6)-alkyl- heterocyclylidenaminocarbonyl, (CrC6)-Alkoxycarbonylheterocyclyliden-(Ci-C6)- alkylaminocarbonyl, (Ci-C6)-Alkoxycarbonyl-(CrC6)-Alkyl((Ci-C6)- alkyl)aminocarbonyl, (Ci-C6)-Alkoxycarbony!-(C3-Cö)- cycloalkylidenaminocarbonyl, Heterocyclyl-N-carbonyl, (Ci-C6)-Alkoxy-(Ci-C6)- alkyiaminocarbonyl steht, Alkoxycarbonyl-heterocyclyl-N-carbonyl, (Ci-C6) -alkoxycarbonyl- (Ci-C6) -alkyl-heterocyclylidenaminocarbonyl, (CrC6) -alkoxycarbonylheterocyclyliden- (Ci-C6) - alkylaminocarbonyl, (Ci-C6) -alkoxycarbonyl- (CrC6 ) -Alkyl ((C 1 -C 6) -alkyl) aminocarbonyl, (C 1 -C 6) -alkoxycarbony! - (C 3 -C 6) -cycloalkylideneaminocarbonyl, heterocyclyl-N-carbonyl, (C 1 -C 6) -alkoxy- (C 1 -C 6) - Alkyiaminocarbonyl stands,
R7, R8, R9, R10, R11 und R12 unabhängig voneinander für Wasserstoff. (d-C7)-Alkyl, (C3-C7)-Cycloalkyl, (C2-C7)-Alkenyl, (C2-C7)-Aikenyl-(Ci-C7)-alkyl, (C1-C7)- Aikoxy-(Ci-C7)-alkyl, Hydroxy-(Ci-C7)-alkyl, (Ci-C7)-Haloalkyl, (C2-C7)-R 7 , R 8 , R 9 , R 10 , R 11 and R 12 are independently hydrogen. (dC 7) alkyl, (C 3 -C 7) cycloalkyl, (C 2 -C 7) alkenyl, (C 2 -C 7) -Aikenyl- (Ci-C7) alkyl, (C1-C7 ) - Aikoxy- (Ci-C 7 ) -alkyl, hydroxy (Ci-C 7 ) -alkyl, (Ci-C 7 ) -haloalkyl, (C 2 -C 7 ) -
Haloalkenyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-alkyl, (Ci-C7)-Aikoxy-(Ci-C7)-haloalkyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-haloalkyl, (CrC7)-Aikoxy, (Ci-C7)-Aikylthio, (C1-C7)- Alkylamino, Halogen, Amino stehen, wobei mindestens eine der Gruppen R7, R8, R9, R10, R1 1 und R12 nicht für Wasserstoff steht und Haloalkenyl, (Ci-C 7 ) -haloalkoxy- (Ci-C 7 ) -alkyl, (Ci-C7) -Aikoxy- (Ci-C 7 ) -haloalkyl, (Ci-C 7 ) -haloalkoxy- (Ci-C 7 ) -haloalkyl, (C 1 -C 7 ) -alkoxy, (C 1 -C 7 ) -alkylthio, (C 1 -C 7 ) -alkylamino, halogen, amino, where at least one of the groups R 7 , R 8 , R 9 , R 10 , R 1 1 and R 12 is not hydrogen, and
R3 und R4 mit dem Atom, an das sie gebunden sind, eine exo-Alkylidengruppe oder einen vollständig gesättigten, gegebenenfalls durch O (Sauerstoff), S R 3 and R 4 with the atom to which they are attached, an exo-alkylidene group or a fully saturated, optionally substituted by O (oxygen), S
(Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und (Sulfur) or a group NH, NR 37 interrupted and
gegebenenfalls weiter substituierten 3 bis 6-gliedrigen Ring bilden,  optionally form further substituted 3 to 6-membered ring,
R1 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 1 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
R1 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, R3 und R7 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 1 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form, R 3 and R 7 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
R3 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, R 3 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
R1 und R3 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 1 and R 3 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
R7 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 7 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
R3 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, R 3 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
R7 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, R 7 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
R13, R14, R 5 und R16 unabhängig voneinander für Wasserstoff, Halogen, Nitro, Amino, Cyano. (Ci-C7)-Alkyl, Aryl, Heteroaryl, (C3-C7)-Cycloalkyl, (C4-C7)-Cycloalkenyl, (C2-C7)-Alkenyl, (C2-C7)-Alkinyl, (C2-C7)-Alkenyl-(Ci-C7)-alkyl, (C2-C7)-Alkinyl- (Ci-C7)-alkyl, Hydroxy, (Ci-C7)-Alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkoxy, (C1-C7)- Alkoxy-(Ci-C7)-alkyl, Hydroxy-(Ci-C7)-alkyl, (Ci-C7)-Haloalkoxy, (C1-C7)- Haloalkyl, (C2-C7)-Haloalkenyl, (C2-C7)-Haloalk!nyl, (Ci-C7)-Haloalkoxy-(Ci-C7)- alkyl, (Ci-C7)-Alkoxy-(CrC7)-haloalkyl, (CrC7)-Haloalkoxy-(Ci-C7)-haloalkyl, Hydrothio, (Ci-C7)-Alkylthio, (d-C7)-Haloalkylthio, (Ci-C7)-Alkyithio-(Ci-C7)- alkyl, (Ci-C7)-Haloalkylthio-(Ci-C7)-alkyl, (Ci-C7)-Alkylamino, Bis-[(Ci-C7)- alkyljamino, (C2-C7)-Alkenylamino, (C3-C7)-Cycloalkylamino, (C1-C7)- Alkylcarbonylamino, (C3-C7)-Cycloalkylcarbonylamino, Arylcarbonylamino, Heteroarylcarbonylamino, Formylamino, (Ci-C7)-Haloalkylcarbonylamino, (Ci-C )-Alkoxycarbonylamino, (Ci-C7)-Alkylaminocarbonylamino, (C1-C7)- Alkyl[(Ci-C7)-Alkyl]aminocarbonylamino, (Ci-C7)-Alkylsulfonyiamino, (C3-C7)- Cycloalkylsulfonylamino, Arylsulfonylamino, Hetarylsulfonylamino, Sulfonyl- (Ci-C7)-haloalkylamino, Amino-(Ci-C7)-alkylsulfonyl, Amino-(Ci-C7)- haloalkylsulfonyl, (Ci-C7)-Alkylaminosulfonyl, Bis[(Ci-C7)-alkyl]aminosulfonyl, (C3-C7)-Cycloalkylaminosulfonyl, (Ci-C7)-Haloalkylaminosulfonyl, R 13 , R 14 , R 5 and R 16 independently represent hydrogen, halogen, nitro, amino, cyano. (Ci-C7) alkyl, aryl, heteroaryl, (C 3 -C 7) cycloalkyl, (C 4 -C 7) cycloalkenyl, (C2-C7) alkenyl, (C 2 -C 7) - alkynyl, (C 2 -C 7) alkenyl (Ci-C7) alkyl, (C 2 -C 7) alkynyl (C 1 -C 7 ) -alkyl, hydroxy, (C 1 -C 7 ) -alkoxy, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -alkoxy, (C 1 -C 7 ) -alkoxy- (C 1 -C 4 -alkyl) 7) alkyl, hydroxy (Ci-C7) alkyl, (Ci-C7) haloalkoxy, (C1-C7) - haloalkyl, (C 2 -C 7) haloalkenyl, (C 2 -C 7) -Haloalk! Nyl, (Ci-C 7 ) -haloalkoxy- (Ci-C 7 ) - alkyl, (Ci-C 7 ) -Alkoxy- (CrC 7 ) -haloalkyl, (CrC 7 ) -haloalkoxy- (Ci-C 7) -haloalkyl, Hydrothio, (Ci-C7) -alkylthio, (dC 7) haloalkylthio, (Ci-C 7) -Alkyithio- (Ci-C7) - alkyl, (Ci-C 7) -Haloalkylthio- (Ci-C7) alkyl, (Ci-C7) alkylamino, - bis [(Ci-C 7) - alkyljamino, (C2-C7) alkenylamino, (C3-C7) cycloalkylamino, (C1 -C 7) -alkylcarbonylamino, (C 3 -C 7 ) -cycloalkylcarbonylamino, arylcarbonylamino, heteroarylcarbonylamino, formylamino, (C 1 -C 7 ) -haloalkylcarbonylamino, (C 1 -C 4 ) -alkoxycarbonylamino, (C 1 -C 7 ) -alkylaminocarbonylamino, (C1- C7) - alkyl [(C 1 -C 7 ) -alkyl] aminocarbonylamino, (C 1 -C 7 ) -alkylsulfonyiamino, (C 3 -C 7 ) -cycloalkylsulfonylamino, arylsulfonylamino, hetarylsulfonylamino, sulfonyl- (C 1 -C 7) -haloalkylamino, amino (Ci -C 7) -alkylsulfonyl, amino- (C 1 -C 7) -haloalkylsulfonyl, (C 1 -C 7) -alkylaminosulfonyl, bis [(C 1 -C 7) -alkyl] aminosulfonyl, (C 3 -C 7) -cycloalkylaminosulfonyl, (C 1 -C 7) -haloalkylaminosulfonyl .
Heteroarylaminosulfonyl, Arylaminosulfonyl, Aryl-(Ci-C7)-alkylaminosulfonyl, (Ci-C7)-Alkylsulfonyl, (C3-C7)-Cycloalkylsulfonyl, Arylsulfonyl, Hydroxycarbonyl, (Ci-C7)-Alkoxycarbonyl, (C3-C7)-Cycloalkoxycarbonyl, (C3-C7)-Cycloalkyl- (Ci-C7)-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C7)-alkoxycarbonyl, (C2-C7)- Alkenyloxycarbonyl, (C2-C7)-Alkinyloxycarbonyl, Aminocarbonyl, (C1-C7)- Alkylaminocarbonyl, Bis[(Ci-C7)-alkyl]aminocarbonyl, (Ci-C7)-Alkyl[(Ci-C7)- Alkyl]aminocarbonyl, (Ci-C7)-Alkyl[(Ci-C7)-Alkoxy]aminocarbonyl, (C2-C7)- Alkenylaminocarbonyl, (C3-C7)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C7)-alkylaminocarbonyl stehen,  Heteroarylaminosulfonyl, arylaminosulfonyl, aryl- (C 1 -C 7) -alkylaminosulfonyl, (C 1 -C 7) -alkylsulfonyl, (C 3 -C 7) -cycloalkylsulfonyl, arylsulfonyl, hydroxycarbonyl, (C 1 -C 7) -alkoxycarbonyl, (C 3 -C 7) -cycloalkoxycarbonyl, (C 3 -C 7) -cycloalkyl- (C 1 -C 7) -alkoxycarbonyl, aryloxycarbonyl, aryl- (C 1 -C 7) -alkoxycarbonyl, (C 2 -C 7) -alkenyloxycarbonyl, (C 2 -C 7) -alkynyloxycarbonyl, aminocarbonyl, (C 1 -C 7 ) - alkylaminocarbonyl, bis [(C 1 -C 7) -alkyl] aminocarbonyl, (C 1 -C 7) -alkyl [(C 1 -C 7) -alkyl] aminocarbonyl, (C 1 -C 7) -alkyl [(C 1 -C 7) -alkoxy] aminocarbonyl, (C 2 -C 7) alkenylaminocarbonyl, (C 3 -C 7) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 7) -alkylaminocarbonyl,
A\ A2, A3 und A4 gleich oder verschieden sind und unabhängig voneinander für NA \ A 2 , A 3 and A 4 are the same or different and are independently N
(Stickstoff) oder die Gruppierungen C-H, C-CH3, C-F, C-Cl, C-Br, C-l, C-OCF3, C-OCH3, C-CF3, C-CO2H, C-CO2CH3 stehen, wobei jedoch in keinem Fall mehr als zwei N-Atome benachbart sind, (Nitrogen) or the groupings CH, C-CH 3, CF, C-Cl, C-Br, CI, C-OCF3, C-OCH3, C-CF 3, C-CO2H, C-CO2CH3 are, however, in no more than two N-atoms are adjacent,
R17 und R18 unabhängig voneinander für Wasserstoff, Halogen, (d-C7)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (C3-C7)-Cycloalkyl, (C2-C7)-Alkenyl, (C2-C7)-Alkinyl, (Ci-C7)-Alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkyl, Aryloxy-(Ci-C7)-alkyl, (C1-C7)- Haloalkoxy, (Ci-C7)-Haloalkyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-alkyl, (Ci-C7)-Alkoxy- (Ci-C7)-haloalkyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-haloalkyl, (Ci-C7)-Alkylthio, (d-C7)-Haloalkylthio, (Ci-C7)-Alkylthio-(d-C7)-alkyl, Hydroxycarbonyl, (C1-C7)- Alkoxycarbonyl, (C3-C7)-Cycloalkoxycarbonyl, (C3-C7)-Cycloalkyl-(Ci-C7)- alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C7)-alkoxycarbonyl, (C2-C7)- Alkenyloxycarbonyl, (C2-C7)-Alkinyloxycarbonyl, Aminocarbonyl, (C1-C7)-R 17 and R 18 independently of one another represent hydrogen, halogen, (C 1 -C 7 ) -alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 7 ) -cycloalkyl, (C 2 -C 7 ) -alkenyl, (C 2 -C 7 ) alkynyl, (C 1 -C 7 ) alkoxy, (C 1 -C 7 ) alkoxy- (C 1 -C 7 ) -alkyl, aryloxy- (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -haloalkoxy , (C 1 -C 7 ) -haloalkyl, (C 1 -C 7 ) -haloalkoxy- (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -alkoxy-, (Ci-C7) haloalkyl, (Ci-C7) haloalkoxy (Ci-C7) haloalkyl, (Ci-C7) -alkylthio, (dC 7) haloalkylthio, (Ci-C7) - alkylthio (dC 7) alkyl, hydroxycarbonyl, (C1-C7) - alkoxycarbonyl, (C3-C 7) cycloalkoxycarbonyl, (C 3 -C 7) cycloalkyl (Ci-C7) - alkoxycarbonyl, aryloxycarbonyl, aryl - (C 1 -C 7 ) -alkoxycarbonyl, (C 2 -C 7 ) -alkenyloxycarbonyl, (C 2 -C 7 ) -alkynyloxycarbonyl, aminocarbonyl, (C 1 -C 7 ) -
Alkylaminocarbonyl, Bis[(Ci-C7)-alkyl]aminocarbonyl, (Ci-C7)-Alkyl[(Ci-C7)- Alkyljaminocarbonyl, (CrC7)-Alkyl[(Ci-C7)-Alkoxy]aminocarbonyl, (C2-C7)- Alkenylaminocarbonyl, (C3-C7)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C7)-alkylaminocarbonyl stehen, Alkylaminocarbonyl, bis [(Ci-C 7) alkyl] aminocarbonyl, (Ci-C 7) alkyl [(Ci-C 7) - Alkyljaminocarbonyl, (CrC 7) alkyl [(Ci-C7) alkoxy] aminocarbonyl , (C 2 -C 7 ) alkenylaminocarbonyl, (C 3 -C 7 ) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 7 ) -alkylaminocarbonyl,
A5 für S (Schwefel), O (Sauerstoff) oder die Gruppierungen N-H, N-CH3, N-CH2CH3, N- CH(CH3)2, N-C02t-Bu, N-Aryl, N-Heteroaryl, N-Heterocyclyl steht, A 5 for S (sulfur), O (oxygen) or the groupings NH, N-CH 3 , N-CH 2 CH 3 , N-CH (CH 3 ) 2 , N-CO 2 t-Bu, N-aryl, N-heteroaryl , N-heterocyclyl,
R20, R23 und R24 unabhängig voneinander für Wasserstoff, (Ci-C7)-Alkyl, Halogen, (C3-C7)-Cycloalkyl, Aryl, Heteroaryl, Heterocyclyl, (C2-C7)-Alkenyl, (C2-C7)- Alkenyl-(CrC7)-alkyl, Aryl-(CrC7)-alkyl, (d-C7)-Alkoxy, (Ci-C7)-Alkoxy-(CrC7)- alkoxy, (Ci-C7)-Alkoxy-(CrC7)-alkyl, Hydroxy, (CrC7)-Haloalkyl, (C1-C7)- Haloalkylthio stehen, und R23 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 20, R 23 and R 24 are independently hydrogen, (Ci-C7) alkyl, halogen, (C 3 -C 7) cycloalkyl, aryl, heteroaryl, heterocyclyl, (C2-C7) alkenyl, ( C2-C7) - alkenyl (-C 7) alkyl, aryl (-C 7) alkyl, (dC 7) alkoxy, (Ci-C7) alkoxy (CrC 7) - alkoxy, (Ci-C 7 ) alkoxy- (C 1 -C 7 ) -alkyl, hydroxy, (C 1 -C 7 ) -haloalkyl, (C 1 -C 7 ) -haloalkylthio, and R 23 having the atoms to which they are attached, a fully saturated or partially saturated, optionally form further substituted 5 to 7-membered ring,
A6, A7 gleich oder verschieden sind und unabhängig voneinander für O (Sauerstoff), S (Schwefel), N-H, N-OCH3, N-CH3 oder die Gruppierung CR21R22 stehen, wobei jedoch in keinem Fall zwei N-, O- oder S-Atome benachbart sind, und wobei R21 und R22 in der Gruppierung CR21R22 jeweils gleiche oder verschiedene A 6 , A 7 are identical or different and independently of one another represent O (oxygen), S (sulfur), NH, N-OCH 3, N-CH 3 or the group CR 21 R 22 , but in no case are two N , O or S atoms are adjacent, and wherein R 21 and R 22 in the group CR 21 R 22 are each the same or different
Bedeutungen gemäß der nachstehenden Definition haben und R21 und R22 unabhängig voneinander für Wasserstoff, Halogen, (Ci-C7)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (C3-C7)-Cycloalkyl, (C2-C7)-Alkenyl, (d-C7)-Alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkyl, Aryloxy-(CrC7)-alkyl, (d-C7)-Haloalkoxy, (C1-C7)- Haloalkyl, (CrC7)-Haloalkoxy-(Ci-C7)-alkyl, (Ci-C7)-Alkoxy-(Ci-C7)-haloalkyl, (Ci-C7)-Haloalkoxy-(CrC7)-haloalkyl, (Ci-C7)-Alkylthio, (Ci-C7)-Haloalkylthio, (Ci-C7)-Alkylthio-(Ci-C-7)-alkyl, Hydroxycarbonyl, (Ci-C-7)-Alkoxycarbonyl, (C3-C7)-Cycloalkoxycarbonyl, (C3-C7)-Cycloalkyl-(CrC7)-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C7)-alkoxycarbonyl, (C2-C7)-Alkenyloxycarbonyl, (C2-C7)-Alkinyloxycarbonyl, Aminocarbonyl, (Ci-C7)-Alkylaminocarbonyl, Bis[(Ci-C7)-alkyl]aminocarbonyl, (Ci-C7)-Alkyl[(Ci-C7)-Alkyl]aminocarbonyl, (CrC7)-Alkyl[(Ci-C7)-Alkoxy]aminocarbonyl, (C2-C7)-Alkenylaminocarbonyi, (C3-C7)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C-7)- alkylaminocarbonyl, Amino, (Ci-C7)-Alkylamino, (C3-C7)-Cycloalkyiamino, Bis- [(Ci-C7)-Alkyl]amino stehen, Have meanings as defined below and R 21 and R 22 are independently hydrogen, halogen, (Ci-C 7) alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 7) cycloalkyl, (C 2 -C 7 ) alkenyl, (dC 7) alkoxy, (Ci-C7) alkoxy (Ci-C7) alkyl, aryloxy- (CrC 7) alkyl, (dC 7) -haloalkoxy, (C1-C7) Haloalkyl, (CrC 7 ) -haloalkoxy- (Ci-C 7 ) -alkyl, (Ci-C 7 ) -alkoxy- (Ci-C 7 ) -haloalkyl, (Ci-C 7 ) -haloalkoxy- (CrC 7 ) haloalkyl, (C 1 -C 7 ) -alkylthio, (C 1 -C 7 ) -haloalkylthio, (C 1 -C 7) -alkylthio (C 1 -C-7) -alkyl, hydroxycarbonyl, (C 1 -C 7) -alkoxycarbonyl, (C 3 -C 7) -cycloalkoxycarbonyl, (C 3 -C 7) -cycloalkyl (C 1 -C 7) - alkoxycarbonyl, aryloxycarbonyl, aryl- (C 1 -C 7) -alkoxycarbonyl, (C 2 -C 7) -alkenyloxycarbonyl, (C 2 -C 7) -alkynyloxycarbonyl, aminocarbonyl, (C 1 -C 7) -alkylaminocarbonyl, bis [(C 1 -C 7) -alkyl] aminocarbonyl, (C 1 -C 7) -alkyl [(C 1 -C 7) -alkyl] aminocarbonyl, (C 1 -C 7) -alkyl [(C 1 -C 7) -alkoxy] -aminocarbonyl, (C 2 -C 7) -alkenylaminocarbonyi, (C 3 -C 7) - Cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 7) -alkylaminocarbonyl, amino, (C 1 -C 7) -alkylamino, (C 3 -C 7) -cycloalkylamino, bis [(C 1 -C 7) -alkyl] -amino,
R25, R26, R28 und R29 unabhängig voneinander für Wasserstoff, (Ci-C7)-Alkyl, Halogen, (C3-C7)-Cycloalkyl, Aryl, Heteroaryl, Heterocyclyl, (C2-C7)-Alkenyl, Aryl-(Ci-C7)- alkyl, (Ci-C7)-Alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)- alkyl, (CrC7)-Haloalkyl stehen, R 25 , R 26 , R 28 and R 29 independently of one another represent hydrogen, (C 1 -C 7 ) -alkyl, halogen, (C 3 -C 7 ) -cycloalkyl, aryl, heteroaryl, heterocyclyl, (C 2 -C 7 ) - alkenyl, aryl (Ci-C7) - alkyl, (Ci-C7) alkoxy, (Ci-C7) alkoxy (Ci-C7) alkoxy, (Ci-C7) alkoxy ( Ci-C7) - alkyl, (CrC 7) -haloalkyl stand,
A8 für O (Sauerstoff), S (Schwefel), N-H, N-CH3, N-OCH3 oder die Gruppierung CHR27 steht und wobei R27 in der Gruppierung CHR27 die Bedeutung gemäß der nachstehenden Definition hat, A 8 is O (oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the moiety CHR 27 , and wherein R 27 in the moiety CHR 27 has the meaning as defined below,
R27 für Wasserstoff, Halogen, (Ci-C7)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (C3-C7)- Cycloalkyl, (C2-C7)-Alkenyl, (CrC7)-Alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkyl, Aryloxy-(Ci-C7)-alkyl, (Ci-C7)-Haloalkoxy, (Ci-C7)-Haloalkyl, (CrC7)-Alkoxy- (Ci-C7)-haloalkyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-haloalkyl, (CrC7)-Alkylthio, R 27 represents hydrogen, halogen, (C 1 -C 7 ) -alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 7 ) -cycloalkyl, (C 2 -C 7 ) -alkenyl, (C 1 -C 7 ) -alkoxy, (Ci-C 7 ) -alkoxy- (C 1 -C 7 ) -alkyl, aryloxy- (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -haloalkoxy, (C 1 -C 7 ) -haloalkyl, (C 1 -C 7 ) -alkoxy (C 1 -C 7 ) -haloalkyl, (C 1 -C 7 ) -haloalkoxy- (C 1 -C 7 ) -haloalkyl, (C 1 -C 7 ) -alkylthio,
(Ci-C7)-Haloalkylthio, (Ci-C7)-Alkylthio-(Ci-C7)-alkyl, Hydroxycarbonyl, (C1-C7)- Alkoxycarbonyl, (C3-C7)-Cycloalkoxycarbonyl, Aryl-(Ci-C7)-alkoxycarbonyl, (C2-C7)-Alkenyloxycarbonyl, (C2-C7)-Alkinyloxycarbonyl, Aminocarbonyl, (C 1 -C 7 ) -haloalkylthio, (C 1 -C 7 ) -alkylthio (C 1 -C 7 ) -alkyl, hydroxycarbonyl, (C 1 -C 7 ) -alkoxycarbonyl, (C 3 -C 7 ) -cycloalkoxycarbonyl, aryl- (C 1 -C 7 ) alkoxycarbonyl, (C 2 -C 7) -alkenyloxycarbonyl, (C 2 -C 7) -alkynyloxycarbonyl, aminocarbonyl,
(Ci-C7)-Alkylaminocarbonyl, Bis[(Ci-C7)-alkyl]aminocarbonyl, (C1-C7)- Alkyl[(Ci-C7)-Alkyl]aminocarbonyl, (Ci-C7)-Alkyl[(Ci-C7)-Alkoxy]aminocarbonyl, (C2-C7)-Alkenylaminocarbonyl, (C3-C7)-Cycloalkylaminocarbonyl,  (C 1 -C 7) -alkylaminocarbonyl, bis [(C 1 -C 7) -alkyl] aminocarbonyl, (C 1 -C 7) -alkyl [(C 1 -C 7) -alkyl] aminocarbonyl, (C 1 -C 7) -alkyl [(C 1 -C 7 ) -Alkoxy] aminocarbonyl, (C 2 -C 7) -alkenylaminocarbonyl, (C 3 -C 7) -cycloalkylaminocarbonyl,
Arylaminocarbonyl, Aryl-(CrC7)-alkylaminocarbonyl, Amino, (Ci-C7)-Alkylamino, (C3-C7)-Cycloalkylamino, Bis-[(d-C7)-Alkyl]amino steht,  Arylaminocarbonyl, aryl- (C 1 -C 7) -alkylaminocarbonyl, amino, (C 1 -C 7) -alkylamino, (C 3 -C 7) -cycloalkylamino, bis- [(C 1 -C 7) -alkyl] -amino,
R30, R31 , R32, R34, R35 und R36 unabhängig voneinander für Wasserstoff, (Ci-C7)-Alkyl, Halogen, (C3-C7)-Cycloalkyl, Aryl, Heteroaryl, Heterocyclyl, (C2-C7)-Alkenyl, (Ci-C7)-Alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkyl, (d-C7)-Haloalkyl, (Ci-C7)-Alkylthio, (d-C7)-Haloalkylthio stehen, R 30 , R 31 , R 32 , R 34 , R 35 and R 36 independently of one another are hydrogen, (C 1 -C 7 ) -alkyl, halogen, (C 3 -C 7 ) -cycloalkyl, aryl, heteroaryl, heterocyclyl, (C 2 -C 4 ) -cycloalkyl, C7) alkenyl, (Ci-C7) alkoxy, (Ci-C7) alkoxy (Ci-C7) alkoxy, (Ci-C7) alkoxy (Ci-C7) alkyl, (dC 7) -haloalkyl , (C 1 -C 7 ) -alkylthio, (C 1 -C 4 ) -haloalkylthio,
A9 für O (Sauerstoff), S (Schwefel), N-H, N-CH3, N-OCH3 oder die Gruppierung CHR33 steht und wobei R33 in der Gruppierung CHR33 die Bedeutung gemäß der nachstehenden Definition hat und A 9 is O (oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the group CHR 33 and wherein R 33 in the group CHR 33 has the meaning as defined below and
R33 für Wasserstoff, Halogen, (d-C7)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (C3-C7)- Cycloalkyl, (C2-C7)-Alkenyl, (Ci-C7)-Alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkyl, Aryloxy-(Ci-C7)-alkyl, (Ci-C7)-Haloalkoxy, (Ci-C7)-Haloalkyl, (Ci-C7)-Alkylthio, (Ci-C7)-Haloalkylthio, Hydroxycarbonyl, (d-C7)-Alkoxycarbonyl, (C3-C7)- Cycloalkoxycarbonyl, Aryl-(Ci-C7)-alkoxycarbonyl, (C2-C7)-Alkenyloxycarbonyl, (C2-C7)-Alkinyloxycarbonyl, Aminocarbonyl, (Ci-C7)-Alkylaminocarbonyl, Bis[(CrC7)-alkyl]aminocarbonyl, (Ci-C7)-Alkyl[(Ci-C7)-Alkyl]aminocarbonyl, (Ci-C7)-Alkyl[(Ci-C7)-Alkoxy]aminocarbonyl, (C2-C7)-Alkenylaminocarbonyl, (C3-C7)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C )- alkylaminocarbonyl, Amino, (Ci-C7)-Alkylamino, (C3-C7)-Cycloalkylamino, Bis- [(Ci-C7)-Alkyl]amino steht, R 33 is hydrogen, halogen, (dC 7) alkyl, aryl, heteroaryl, heterocyclyl, (C3-C7) - cycloalkyl, (C 2 -C 7) alkenyl, (Ci-C7) alkoxy, (C -C 7) alkoxy (Ci-C7) alkyl, aryloxy (Ci-C7) alkyl, (Ci-C7) haloalkoxy, (Ci-C7) haloalkyl, (Ci-C 7 ) -Alkylthio, (C 1 -C 7 ) -haloalkylthio, hydroxycarbonyl, (C 1 -C 4 ) -alkoxycarbonyl, (C 3 -C 7 ) -cycloalkoxycarbonyl, aryl- (C 1 -C 7 ) -alkoxycarbonyl, (C 2 -C 7 ) -alkenyloxycarbonyl, (C 2 -C 7 ) -alkynyloxycarbonyl, aminocarbonyl, (C 1 -C 7 ) -alkylaminocarbonyl, bis [(C 1 -C 7 ) -alkyl] aminocarbonyl, (C 1 -C 7 ) -alkyl [(C 1 -C 7 ) -alkyl] aminocarbonyl , (C 1 -C 7 ) -alkyl [(C 1 -C 7 ) -alkoxy] -aminocarbonyl, (C 2 -C 7 ) -alkenylaminocarbonyl, (C 3 -C 7 ) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 4) -alkylaminocarbonyl , Amino, (C 1 -C 7 ) -alkylamino, (C 3 -C 7 ) -cycloalkylamino, bis- [(C 1 -C 7 ) -alkyl] -amino,
R37 für (Ci-C/)-Alkyl. Aryl, Heteroaryl, Heterocyclyl, (C3-C7)-Cycloalkyl, (C2-C7)-Alkenyl, (d-C7)-Alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkyl, Aryloxy-(Ci-C7)-alkyl, (C1-C7)- Alkoxycarbonyl, (C3-C7)- Cycloalkoxycarbonyl, Aryl-(Ci-C7)-alkoxycarbonyl, (C-2-C7)-Alkenyloxycarbonyl, (C2-C7)-Alkinyloxycarbonyl, (d-C7)-Alkylcarbonyl, (C3-C7)-Cycloalkylcarbonyl, Arylcarbonyl, Heteroarylcarbonyl steht. R 37 is (Ci-C /) -alkyl. Aryl, heteroaryl, heterocyclyl, (C 3 -C 7) cycloalkyl, (C 2 -C 7) alkenyl, (dC 7) alkoxy, (Ci-C7) alkoxy (Ci-C7) alkyl , aryloxy (Ci-C7) alkyl, (C1-C7) - alkoxycarbonyl, (C3-C7) - cycloalkoxycarbonyl, aryl (Ci-C7) -alkoxycarbonyl, (C-2-C 7) alkenyloxycarbonyl , (C 2 -C 7) -alkynyloxycarbonyl, (dC 7) alkylcarbonyl, (C3-C7) cycloalkylcarbonyl, arylcarbonyl, heteroarylcarbonyl stands.
Bevorzugt sind Verbindungen der allgemeinen Formel (I), worin Preference is given to compounds of the general formula (I) in which
[X-Y] für die Gruppierung [X-Y] for grouping
[x-YT steht, Q für die Gruppierungen Q-1 bis Q-6 [x-YT stands, Q stands for the groupings Q-1 to Q-6
steht, wobei R13, R14, R15, R16, R17, R18, R19, R20, R23, R24, R25, R26, R28, R29,R 13 , R 14 , R 15 , R 16 , R 17 , R 18 , R 19 , R 20 , R 23 , R 24 , R 25 , R 26 , R 28 , R 29
R30, R31, R32, R34, R35 und R36 sowie A1 bis A9 jeweils die Bedeutung gemäß der nachstehenden Definitionen haben und wobei der Pfeil für eine Bindung zur jeweiligen Gruppierung C-R6 in der allgemeinen Formel (I) steht, für (Ci-C6)-Alkyl, (C3-C6)-Cycloalkyl, (C4-C6)-Cycloalkenyl, (C2-C6)-Alkenyl, (C2-C6)-Alkinyl, (C2-C6)-Alkenyl-(Ci-C6)-alkyl, (C2-C6)-Alkinyl-(Ci-C6)-alkyl, (Ci-C6)-Alkoxy-(Ci-C6)-alkyl, Hydroxy-(Ci-C6)-alkyl, (Ci-C6)-Haloalkyl, (C2-C6)- Haloalkenyl, (C2-C6)-Haloalkinyl steht, R2, R3 und R4 unabhängig voneinander für Wasserstoff, Fluor, (d-CeJ-Alkyl, (Ca-Co)- Cycloalkyl, (C4-C6)-Cycloalkenyl, (C2-C6)-Alkenyl, (C2-Cr>)-Alkinyl, (C2-C6)- Alkenyl-(Ci-C6)-alkyl, (C2-C6)-Alkinyl-(Ci-C6)-alkyl, (Ci-C6)-Alkoxy-(Ci-C6)-alkyl, Hydroxy-(CrC6)-alkyl, (Ci-C6)-Haloalkyl stehen, für Hydroxy, (Ci-Cej-Alkoxy, Aryloxy, (Ca-CeJ-Cycloalkyloxy, (C2-C6)-Alkenyloxy, (C2-C6)-Alkenyl-(Ci-C6)-alkyloxy, (Ci-C6)-Alkoxy-(Ci-C6)-alkyloxy, (Ci-C6)- Alkylcarbonyloxy, Arylcarbonyloxy, Heteroarylcarbonyloxy, (Ca-Co)- Cycloalkylcarbonyloxy, (d-CeJ-Alkoxycarbonyloxy, (Cz-Ce)- Alkenyloxycarbonyloxy, Aryloxy-(d-C6)-alkyloxy, Aryl-(Ci-C6)-alkyloxy, (Ci-Ce)- Alkoxy-(Ci-C6)-alkoxy-(Ci-C6)-alkyloxy, (Ci-C6)-Alkylthio-(Ci-C6)-alkyloxy, Ths[(Ci-C6)-alkyl]silyloxy, (Ci-C6)-Alkyl-Bis[(Ci-C6)-alkyl]silyloxy, (Ci-Ce)-Alkyl- bis(Aryl)silyloxy, Aryl-bis[(Ci-C6)-alkyl]silyloxy, Cycloalkyl-bis[(Ci-C6)- alkyljsilyloxy, Halo-bis[(Ci-C6)-alkyl]silyloxy, Tris[(Ci-C6)-aikyl]silyl-(Ci-C6)- alkoxy-(Ci-C6)-alkyloxy, sieht, für (d-Ce)- Alkylsulfonylaminocarbonyl, (C3-G5)-R 30 , R 31 , R 32 , R 34 , R 35 and R 36 and A 1 to A 9 each have the meaning according to the definitions below and wherein the arrow for a bond to the respective group CR 6 in the general formula (I) (C 1 -C 6 ) -alkyl, (C 3 -C 6 ) -cycloalkyl, (C 4 -C 6 ) -cycloalkenyl, (C 2 -C 6 ) -alkenyl, (C 2 -C 6 ) - alkynyl, (C2-C6) alkenyl (Ci-C 6) alkyl, (C 2 -C 6) alkynyl (Ci-C 6) alkyl, (Ci-C 6) alkoxy (C -C 6) alkyl, hydroxy (Ci-C 6) alkyl, (Ci-C 6) -haloalkyl, (C 2 -C 6) - haloalkenyl, (C 2 -C 6) haloalkynyl, R 2, R 3 and R 4 independently of one another represent hydrogen, fluorine, (C 1 -C 6 -alkyl, (C 1 -C 6 ) -cycloalkyl, (C 4 -C 6 ) -cycloalkenyl, (C 2 -C 6 ) -alkenyl, (C 2 -Cr>) -alkynyl, (C 2 -C 6) - alkenyl, (Ci-C 6) alkyl, (C 2 -C 6) alkynyl (Ci-C 6) alkyl, (Ci-C 6 ) Alkoxy- (Ci-C 6 ) alkyl, hydroxy (CrC 6 ) alkyl, (Ci-C 6 ) haloalkyl, for hydroxy, (Ci-Cej-alkoxy, aryloxy, (Ca-CeJ-cycloalkyloxy , (C 2 -C 6 ) -alkenyloxy, (C 2 -C 6 ) -alkenyl- (C 1 -C 6 ) -alkyloxy, (C 1 -C 6 ) -alkoxy- (C 1 -C 6 ) -alkyloxy, (C 1 -C 6 ) -alkylcarbonyloxy, arylcarbonyloxy, heteroarylcarbonyloxy, (Ca-Co) -cycloalkylcarbonyloxy, (d-CeJ-alkoxycarbonyloxy, ( Cz-Ce) - alkenyloxycarbonyloxy, aryloxy- (C 1 -C 6 ) -alkyloxy, aryl- (C 1 -C 6 ) -alkyloxy, (C 1 -C 6 ) -alkoxy- (C 1 -C 6 ) -alkoxy- (C 1 -C 6 ) -alkyloxy, (C 1 -C 6 ) -alkylthio (C 1 -C 6 ) -alkyloxy, Ths [(C 1 -C 6 ) -alkyl] silyloxy, (C 1 -C 6 ) -alkyl-bis [(C 1 -C 6 ) -alkyl ] silyloxy, (C 1 -C 6) -alkyl bis (aryl) silyloxy, aryl bis [(Ci-C6) alkyl] silyloxy, cycloalkyl bis [(Ci-C6) alkylsilyloxy, halo bis [(Ci-C 6 ) alkyl] silyloxy, Tris [( C 1 -C 6 ) -alkyl] silyl- (C 1 -C 6 ) -alkoxy- (C 1 -C 6 ) -alkyloxy, see, for (C 1 -C 6 ) -alkylsulfonylaminocarbonyl, (C 3 -G 5) -
Cycloalkylsulfonylaminocarbonyl, Hydroxycarbonyl, (Ci-C6)-Alkoxycarbonyl, (C-3-C6)-Cycloalkoxycarbonyl, (C3-Cö)-Cycloalkyl-(Ci-C6)-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C6)-alkoxycarbonyl, (C2-C6)-Alkenyloxycarbonyl, (C2-Cö)-Alkinyloxycarbonyl, (Ci-C6)-Haloalkyloxycarbonyl, (Ci-C6)-Alkoxy- (Ci-C6)-alkoxycarbonyl, (C2-C6)-Alkenyloxy-(Ci-C6)-alkoxycarbonyl, (Ci-Ce)- Alkylamino-(CrC6)-alkoxycarbonyl, T s[(Ci-C6)-alkyl]silyloxy-(CrC6)- alkoxycarbonyl, Bis[(CrC6)-Alkyl]amino-(Ci-C6)-alkoxycarbonyl, (d-Cr,)- Alkyl[(Ci-C6)-alkyl]amino-(CrC6)-alkoxycarbonyl, Cyano-(Ci-Ce)- alkoxycarbonyl, Heterocyclyl-N-(CrC6)-alkoxycarbonyl, Heteroaryloxycarbonyl, Heteroaryl-(Ci-C6)-alkoxycarbonyl, Heterocyclyl-(Ci-C6)-alkoxycarbonyl, Heterocyclyloxycarbonyl, (C2-C6)-Alkenyl-(CrC6)-alkoxycarbonyl, (C2-C13)- Alkinyl-(Ci-C6)-alkoxycarbonyl, Aryl-(C2-C6)-alkinyloxycarbonyl, Aryl-(C2-Cc>)- alkenyloxycarbonyl, Aminocarbonyl, (Ci-C6)-Alkylaminocarbonyl, Bis[(Ci-C6)- alkyl]aminocarbonyl, (Ci-C6)-Alkyl[(Ci-C6)-Alkyl]aminocarbonyl, (Ci-Ce)- Alkyl[(Ci-C6)-Alkoxy]aminocarbonyl, (C2-C6)-Alkenylaminocarbonyl, (Ca-Ce)- Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C6)-alkylaminocarbonyl, Heteroaryl-(Ci-C6)-alkylaminocarbonyl, Cyano-(Ci-C6)-alkylaminocarbonyl, (CrC6)-Haloalkylaminocarbonyl, (C2-C6)-Alkinyl-(CrC6)-alkylaminocarbonyl, (Ci-C6)-Alkoxycarbonylaminocarbonyl, Aryl-(Ci-Ce)- alkoxycarbonylaminocarbonyl, Hydroxycarbonyl-(Ci-Cr,)-alkyl, (d-Ce)- Alkoxycarbonyl-(d-C6)-alkyl, (C3-C6)-Cycloalkoxycarbonyl-(CrC6)-alkyl, (C3-C6)-Cycloalkyl-(Ci-C6)-alkoxycarbonyl-(Ci-Cö)-alkyl, (C2-C6)- Alkenyloxycarbonyl-(Ci-C6)-alkyl, Aryl-(Ci-C6)-alkoxycarbonyl-(Ci-C6)-alkyl, (Ci-C6)-Alkylaminocarbonyl-(Ci-C6)-alkyl, Aminocarbonyl-(Ci-C6)-alkyl, Cycloalkylsulfonylaminocarbonyl, hydroxycarbonyl, (C 1 -C 6) -alkoxycarbonyl, (C 3 -C 6) -cycloalkoxycarbonyl, (C 3 -C 6) -cycloalkyl- (C 1 -C 6) -alkoxycarbonyl, aryloxycarbonyl, aryl- (C 1 -C 6) -alkoxycarbonyl, (C 2 -C 6) -alkenyloxycarbonyl, (C 2 -C 6) -alkynyloxycarbonyl, (C 1 -C 6) -haloalkyloxycarbonyl, (C 1 -C 6) -alkoxy- (C 1 -C 6) -alkoxycarbonyl, (C 2 -C 6) -alkenyloxy- (Ci -C 6) alkoxycarbonyl, (C 1 -C 6) alkylamino (C 1 -C 6) alkoxycarbonyl, T s [(C 1 -C 6) alkyl] silyloxy (C 1 -C 6) alkoxycarbonyl, bis [(C 1 -C 6) alkyl] amino ( Ci-C6) -alkoxycarbonyl, (d-Cr,) - alkyl [(Ci-C6) alkyl] amino- (CrC6) alkoxycarbonyl, cyano (Ci-Ce) alkoxycarbonyl, heterocyclyl-N- (CrC6) - alkoxycarbonyl, heteroaryloxycarbonyl, heteroaryl- (Ci-C6) -alkoxycarbonyl, heterocyclyl- (Ci-C6) -alkoxycarbonyl, heterocyclyloxycarbonyl, (C2-C6) -alkenyl- (CrC6) -alkoxycarbonyl, (C2-C13) -alkynyl- (Ci C6) -alkoxycarbonyl, aryl (C2-C6) -alkynyloxycarbonyl, aryl (C2-Cc>) - alkenyloxycarbonyl, aminocarbonyl, (Ci-C6) alkylaminocarbonyl, bis [(Ci-C6) - alkyl] aminocarbonyl, ( Ci-C6) alkyl [(Ci-C6 ) -Alkyl] aminocarbonyl, (C 1 -C 6) -alkyl [(C 1 -C 6) -alkoxy] -aminocarbonyl, (C 2 -C 6) -alkenylaminocarbonyl, (C 2 -C 6) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 6) - alkylaminocarbonyl, heteroaryl- (C 1 -C 6) -alkylaminocarbonyl, cyano- (C 1 -C 6) -alkylaminocarbonyl, (C 1 -C 6) -haloalkylaminocarbonyl, (C 2 -C 6) -alkynyl- (C 1 -C 6) -alkylaminocarbonyl, (C 1 -C 6) -alkoxycarbonylaminocarbonyl, Aryl- (Ci-Ce) alkoxycarbonylaminocarbonyl, hydroxycarbonyl- (Ci-Cr,) -alkyl, (d-Ce) -alkoxycarbonyl- (d-C6) -alkyl, (C3-C6) -cycloalkoxycarbonyl- (CrC6) -alkyl , (C 3 -C 6 ) -cycloalkyl- (C 1 -C 6 ) -alkoxycarbonyl- (C 1 -C 6 ) -alkyl, (C 2 -C 6 ) -alkenyloxycarbonyl- (C 1 -C 6 ) -alkyl, aryl- (C 1 -C 6 ) -alkoxycarbonyl- (C 1 -C 6) -alkyl, (C 1 -C 6) -alkylaminocarbonyl- (C 1 -C 6) -alkyl, aminocarbonyl- (C 1 -C 6) -alkyl,
Bis[(CrC6)-alkyl]aminocarbonyl-(Ci-C6)-alkyl, (C3-C6)-Cycloalkylaminocarbonyl- (Ci-C6)-alkyl, Aryl-(Ci-C6)-alkylaminocarbonyl-(Ci-C6)-alkyl, Heteroaryl-(Ci-C6)- alkylaminocarbonyl-(Ci-C6)-alkyl, Cyano-(Ci-C6)-alkylaminocarbonyl-(Ci-C6)- alkyl, (Ci-C6)-Haloalkylaminocarbonyl-(Ci-C6)-alkyl, (C2-C6)-Alkinyl-(Ci-C6)- alkylaminocarbonyl-(Ci-C6)-alkyl, (C3-C6)-Cycloalkyl-(Ci-C6)- alkylaminocarbonyl-(Ci-C-6)-alkyl, (Ci-C6)-Alkoxycarbonylaminocarbonyl- (d-C6)-alkyl, Aryl-(Ci-C6)-alkoxycarbonylaminocarbonyl-(CrC6)-alkyl, (d-Ce)- Alkoxycarbonyl-(Ci-C6)-alkylaminocarbonyl, Hydroxycarbonyl-(Ci-C6)- alkylaminocarbonyl, Aryl-(Ci-C6)-alkoxycarbonyl-(CrC6)-alkylaminocarbonyl, Aminocarbonyl-(Ci-C6)-alkylaminocarbonyl, (d-Cc -Alkylaminocarbonyl- (Ci-C6)-alkylaminocarbonyl. Bis [(CRC6) alkyl] aminocarbonyl (Ci-C6) alkyl, (C3-C6) -Cycloalkylaminocarbonyl- (Ci-C 6) alkyl, aryl (Ci-C6) alkylaminocarbonyl (Ci-C 6 ) -alkyl, heteroaryl- (C 1 -C 6 ) -alkylaminocarbonyl- (C 1 -C 6 ) -alkyl, cyano- (C 1 -C 6 ) -alkylaminocarbonyl- (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -haloalkylaminocarbonyl- (Ci-C 6) alkyl, (C2-C6) alkynyl (Ci-C6) - alkylaminocarbonyl (Ci-C 6) alkyl, (C3-C6) cycloalkyl (Ci-C 6 ) - alkylaminocarbonyl- (C 1 -C 6) -alkyl, (C 1 -C 6) -alkoxycarbonylaminocarbonyl- (C 1 -C 6) -alkyl, aryl- (C 1 -C 6) -alkoxycarbonylaminocarbonyl- (C 1 -C 6) -alkyl, (C 1 -C 6) - Alkoxycarbonyl- (C 1 -C 6) -alkylaminocarbonyl, hydroxycarbonyl- (C 1 -C 6) -alkylaminocarbonyl, aryl- (C 1 -C 6) -alkoxycarbonyl- (C 1 -C 6) -alkylaminocarbonyl, aminocarbonyl- (C 1 -C 6) -alkylaminocarbonyl, (d-Cc -Alkylaminocarbonyl- (C 1 -C 6) -alkylaminocarbonyl.
(C3-C6)-Cycloalkylaminocarbonyl-(Ci-C6)-alkylaminocarbonyl, (C3-C6)- Cycloalkyl-(Ci-C6)-alky!aminocarbonyl, (C3-C6)-Cycloalkyl-(Ci-C6)- alkylaminocarbonyl-(Ci-Cö)-alkyL (C3-C6)-Cycloalkyl-(Ci-Cö)- alkylaminocarbonyl-(Ci-C6)-alkylaminocarbonyl, (C2-C6)-Alkenyl-(Ci-C6)- alkylaminocarbonyl, (C2-C6)-Alkenylaminocarbonyl-(CrC6)-alkyl, (C2-Ce)- Alkenyl-(Ci-C6)-alkylaminocarbonyl-(Ci-C6)-alkyl, (Ci-C6)-Alkylcarbonyl, (C3-C6)- Cycloalkylcarbonyl, Arylcarbonyl, Formyl, Hydroxyiminomethyl, (C 3 -C 6 ) -cycloalkylaminocarbonyl- (C 1 -C 6 ) -alkylaminocarbonyl, (C 3 -C 6 ) -cycloalkyl- (C 1 -C 6 ) -alkylaminocarbonyl, (C 3 -C 6 ) -cycloalkyl- (C 1 -C 6 ) alkylaminocarbonyl- (C 1 -C 6) -alkyL (C 3 -C 6) -cycloalkyl- (C 1 -C 6) -alkylaminocarbonyl- (C 1 -C 6) -alkylaminocarbonyl, (C 2 -C 6) -alkenyl- (C 1 -C 6) -alkylaminocarbonyl, (C2-C6) -Alkenylaminocarbonyl- (CRC6) alkyl, (C2-Ce) - alkenyl, (Ci-C6) alkylaminocarbonyl (Ci-C 6) alkyl, (Ci-C 6) alkylcarbonyl, (C 3 -C 6 ) - cycloalkylcarbonyl, arylcarbonyl, formyl, hydroxyiminomethyl,
Aminoiminomethyl, (Ci-CeJ-Alkoxyiminomethyl, (CrCeJ-Alkylaminoiminomethyl, Bis[(Ci-C6)-alkyl]aminoiminomethyl, (C3-C6)-Cycloalkoxyiminomethyl, (Ca-Ce)- Cycloalkyl-(CrC6)-alkoximinomethyl, Aryloximinomethyl, Aryl-(Ci-Ce)- alkoxyiminomethyl, Aryl-(Ci-C6)-alkylaminoiminomethyl, (C2-C-6)- Alkenyloxyiminomethyl, Arylaminoiminomethyl, Arylsulfonylaminoiminomethyl, Hydroxycarbonylheterocyclyl-(Ci-C6)-alkyl, (Ci-CeJ-Alkoxycarbonylheterocyclyl- (Ci-Co)-alkyl, Hydroxycarbonyl-(C3-C6)-cycloalkyl-(Ci-Cö)-alkyl, (Ci-Ce)- Alkoxycarbonyl-(C3-C6)-cycloalkyl-(Ci-C6)-alkyl, Hydroxyaminocarbonyl,  Aminoiminomethyl, (C 1 -C 6) -alkoxyiminomethyl, (C 1 -C 6 -alkylaminoiminomethyl, bis [(C 1 -C 6) -alkyl] aminoiminomethyl, (C 3 -C 6) -cycloalkoxyiminomethyl, (C 2 -C 6) -cycloalkyl- (C 1 -C 6) -alkoximinomethyl, aryloximinomethyl, Aryl- (C 1 -C 6) -alkoxyiminomethyl, aryl- (C 1 -C 6) -alkylaminoiminomethyl, (C 2 -C 6) -alkenyloxyiminomethyl, arylaminoiminomethyl, arylsulfonylaminoiminomethyl, hydroxycarbonylheterocyclyl- (C 1 -C 6) -alkyl, (C 1 -C 12 -alkoxycarbonylheterocyclyl - (Ci-Co) -alkyl, hydroxycarbonyl- (C3-C6) -cycloalkyl- (Ci-Cö) -alkyl, (Ci-Ce) - alkoxycarbonyl- (C3-C6) -cycloalkyl- (Ci-C6) -alkyl , Hydroxyaminocarbonyl,
(Ci-C6)-Alkoxyaminocarbonyl, Aryl-(Ci-C6)-alkoxyaminocarbonyl, (d-Ce)- Alkoxycarbonyl-heterocyclyl-N-carbonyl, (CrC6)-Alkoxycarbonyl-(Ci-C6)-alkyl- heterocyclylidenaminocarbonyl, (CrC6)-Alkoxycarbonylheterocyclyliden-(Ci-C6)- alkylaminocarbonyl, (Ci-C6)-Alkoxycarbonyl-(Ci-C6)-Alkyl((d-C6)- alkyl)aminocarbonyl, (Ci-C6)-Alkoxycarbonyl-(C3-C6)- cycloalkylidenaminocarbonyl, Heterocyclyl-N-carbonyl, (Ci-C6)-Alkoxy-(Ci-C6)- alkylaminocarbonyl steht,  (C 1 -C 6) -alkoxyaminocarbonyl, aryl- (C 1 -C 6) -alkoxyaminocarbonyl, (C 1 -C 6) -alkoxycarbonyl-heterocyclyl-N-carbonyl, (C 1 -C 6) -alkoxycarbonyl- (C 1 -C 6) -alkyl-heterocyclylideneaminocarbonyl, (C 1 -C 6 ) Alkoxycarbonylheterocyclylido- (C 1 -C 6) -alkylaminocarbonyl, (C 1 -C 6) -alkoxycarbonyl- (C 1 -C 6) -alkyl ((C 1 -C 6) -alkyl) aminocarbonyl, (C 1 -C 6) -alkoxycarbonyl- (C 3 -C 6) ) - cycloalkylidenaminocarbonyl, heterocyclyl-N-carbonyl, (C 1 -C 6) -alkoxy- (C 1 -C 6) -alkylaminocarbonyl,
R7, R8, R9, R10, R11 und R12 unabhängig voneinander für Wasserstoff, (CrC6)-Alkyl, (C3-C6)-Cyc!oalkyl, (C2-C6)-Alkenyl, (C2-C6)-Alkenyl-(Ci-C6)-alkyl, (Ci-C6)- Alkoxy-(CrC6)-alkyl, Hydroxy-(CrC6)-aikyl, (CrC6)-Haloalkyl, (C2-C6)- Haloaikenyl, (Ci-C6)-Haloalkoxy-(Ci-C6)-aikyl, (Ci-C6)-Alkoxy-(Ci-C6)-haloalkyl, (Ci-C6)-Haloalkoxy-(Ci-C6)-haloalkyl, (Ci-C6)-Alkoxy, (Ci-Ce)-Alkylthio, (Ci-C6)- Alkylamino, Halogen, Amino stehen, wobei mindestens eine der Gruppen R7,R 7, R 8, R 9, R 10, R 11 and R 12 independently represent hydrogen, (CrC 6) alkyl, (C 3 -C 6) -Cyc! Oalkyl, (C 2 -C 6) alkenyl , (C2-C6) alkenyl (Ci-C 6) alkyl, (Ci-C6) - alkoxy (CrC 6) alkyl, hydroxy (CrC 6) -alkyl, (CrC 6) -haloalkyl , (C 2 -C 6 ) - Haloaikenyl, (Ci-C6) -haloalkoxy- (Ci-C 6 ) -aikyl, (Ci-C 6 ) -Alkoxy- (Ci-C 6 ) -haloalkyl, (Ci-C 6 ) -haloalkoxy- (C 1 -C 6 ) -haloalkyl, (C 1 -C 6 ) -alkoxy, (C 1 -C 6 ) -alkylthio, (C 1 -C 6 ) - Alkylamino, halogen, amino, wherein at least one of the groups R 7 ,
R8, R9, R10, R11 und R12 nicht für Wasserstoff steht und R 8 , R 9 , R 10 , R 11 and R 12 are not hydrogen and
R3 und R4 mit dem Atom, an das sie gebunden sind, eine exo-Alkylidengruppe oder einen vollständig gesättigten, gegebenenfalls durch O (Sauerstoff), S R 3 and R 4 with the atom to which they are attached, an exo-alkylidene group or a fully saturated, optionally substituted by O (oxygen), S
(Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 6-gliedrigen Ring bilden, (Sulfur) or a group NH, NR 37 form interrupted and optionally further substituted 3 to 6-membered ring,
R1 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 1 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
R1 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, R 1 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
R3 und R7 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 3 and R 7 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
R3 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, R 3 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
R1 und R3 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R7 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 1 and R 3 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 5 to 7-membered ring form, R 7 and R 11 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 5 to 7-membered ring form,
R3 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, R 3 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
R7 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, R 7 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
R13, R14, R15 und R16 unabhängig voneinander für Wasserstoff, Fluor, Chlor, Brom, lod, Nitro, Amino, Cyano, (Ci-Ce)-Alkyl, gegebenenfalls substituiertes Phenyl, Heteroaryl, (C3-C6)-Cycloalkyl, (C4-C6)-Cycloalkenyl, (C2-C6)-Alkenyl, (C2-C6)- Alkinyl, (C2-C6)-Alkenyl-(Ci-C6)-alkyl, (C2-C6)-Alkinyl-(Ci-C6)-alkyl, Hydroxy, (Ci-Co)-Alkoxy, (Ci-C6)-Alkoxy-(Ci-C6)-alkoxy, (Ci-C6)-Alkoxy-(Ci-C6)-alkyl,R 13 , R 14 , R 15 and R 16 independently of one another represent hydrogen, fluorine, chlorine, bromine, iodine, nitro, amino, cyano, (C 1 -C 6 ) -alkyl, optionally substituted phenyl, heteroaryl, (C 3 -C 6 ) cycloalkyl, (C 4 -C 6) -cycloalkenyl, (C 2 -C 6) alkenyl, (C 2 -C 6) - alkynyl, (C2-C6) alkenyl (Ci-C 6) - alkyl, (C 2 -C 6 ) -alkynyl (C 1 -C 6 ) -alkyl, hydroxy, (C 1 -C 6 ) -alkoxy, (C 1 -C 6 ) -alkoxy- (C 1 -C 6 ) -alkoxy, C 6 ) -alkoxy- (C 1 -C 6 ) -alkyl,
Hydroxy-(CrC6)-alkyl, (Ci-Ce)-Haloalkoxy, (Ci-C6)-Haloalkyl, (C2-C6)- Haloalkenyl, (C2-C6)-Haloalkinyl, (Ci-C6)-Haloalkoxy-(Ci-C6)-alkyl, (Ci-C6)- Alkoxy-(Ci-C6)-haloalkyl, (Ci-C6)-Haloalkoxy-(Ci-C6)-haloalkyl, Hydrothio, Hydroxy (CrC 6) alkyl, (Ci-Ce) haloalkoxy, (Ci-C 6) -haloalkyl, (C 2 -C 6) - haloalkenyl, (C2-C6) haloalkynyl, (Ci-C 6 ) haloalkoxy (Ci-C 6) alkyl, (Ci-C6) - alkoxy- (Ci-C 6) -haloalkyl, (Ci-C 6) haloalkoxy (Ci-C 6) -haloalkyl, Hydrothio .
(Ci-Ce)-Alkylthio, (Ci-C6)-Haloalkylthio, (Ci-C6)-Alkylthio-(Ci-C6)-alkyl, (Ci-C6)- Haloalkylthio-(Ci-C6)-alkyl, (Ci-C6)-Alkylamino, Bis-[(Ci-C6)-alkyl]amino,(C 1 -C 6 ) -alkylthio, (C 1 -C 6 ) -haloalkylthio, (C 1 -C 6 ) -alkylthio (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -haloalkylthio (C 1 -C 6 ) alkyl, (C 1 -C 6 ) -alkylamino, bis - [(C 1 -C 6 ) -alkyl] -amino,
(C2-C-6)-Alkenylamino, (C3-C6)-Cycloalkylamino, (Ci-C6)-Alkylcarbonylamino, (Ca-CeJ-Cycloalkylcarbonylamino, Arylcarbonylamino, Heteroarylcarbonylamino, Formylamino, (Ci-C6)-Haloalkylcarbonylamino, (Ci-C6)-Alkoxycarbonylamino, (Ci-C6)-Alkylaminocarbonylamino, (Ci-Ce)- Alkyl[(Ci-Cö)- Alkyl]aminocarbonylamino, (Ci-C6)-Alkylsulfonylamino, (Ca-Ce)-(C 2 -C 6) alkenylamino, (C 3 -C 6) -cycloalkylamino, (C 1 -C 6) -alkylcarbonylamino, (Ca-CeJ-cycloalkylcarbonylamino, arylcarbonylamino, heteroarylcarbonylamino, formylamino, (C 1 -C 6) -haloalkylcarbonylamino, (Ci -C 6) alkoxycarbonylamino, (C 1 -C 6) -alkylaminocarbonylamino, (C 1 -C 6) -alkyl [(C 1 -C 6) -alkyl] aminocarbonylamino, (C 1 -C 6) -alkylsulfonylamino, (Ca-Ce) -
Cycloalkylsulfonylamino, Arylsulfonylamino, Hetarylsulfonylamino, Sulfonyl- (d-Cr -haloalkylamino, Amino-(CrC6)-alkylsulfonyl, Amino-(Ci-C6)- haloalkylsulfonyl, (Ci-C6)-Alkylaminosulfonyl, Bis[(Ci-C6)-alkyl]aminosulfonyl, (Ca-CeJ-Cycloalkylaminosulfonyl, (CrC6)-Haloalkylaminosulfonyl, Heteroarylaminosulfonyl, Arylaminosulfonyl, Aryl-(Ci-C6)-alkylaminosulfonyl, (CrCeJ-Alkylsulfonyl, (C3-C6)-Cycloalkylsulfonyl, Arylsulfonyl, Hydroxycarbonyl, (Ci-C-6)-Alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, (Ca-CeJ-Cycloalkyl- (Ci-C6)-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(d-C6)-alkoxycarbonyl, (C2-Ce)- Alkenyloxycarbonyl, (C2-C6)-Alkinyloxycarbonyl, Aminocarbonyl, (d-Ce)- Alkylaminocarbonyl, Bis[(CrC6)-alkyl]aminocarbonyl, (Ci-C6)-Alkyl[(d-C6)- Alkyljaminocarbonyl, (Ci-C6)-Alkyl[(Ci-C6)-Alkoxy]aminocarbonyl, (C2-C6)- Alkenylaminocarbonyl, (Ca-CeJ-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C6)-alkylaminocarbonyl stehen, Cycloalkylsulfonylamino, arylsulfonylamino, hetarylsulfonylamino, sulfonyl- (d-Cr-haloalkylamino, amino- (CrC6) -alkylsulfonyl, amino- (Ci-C6) -haloalkylsulfonyl, (Ci-C6) -alkylaminosulfonyl, bis [(Ci-C6) -alkyl ] aminosulfonyl, (Ca-CeJ-cycloalkylaminosulfonyl, (CrC6) -haloalkylaminosulfonyl, Heteroarylaminosulfonyl, arylaminosulfonyl, aryl- (C 1 -C 6) -alkylaminosulfonyl, (C 1 -C 6 -alkylsulfonyl, (C 3 -C 6) -cycloalkylsulfonyl, arylsulfonyl, hydroxycarbonyl, (C 1 -C 6) -alkoxycarbonyl, (C 3 -C 6) -cycloalkoxycarbonyl, ( Ca-CeJ-cycloalkyl- (C 1 -C 6) -alkoxycarbonyl, aryloxycarbonyl, aryl- (C 1 -C 6) -alkoxycarbonyl, (C 2 -C 6) -alkenyloxycarbonyl, (C 2 -C 6) -alkynyloxycarbonyl, aminocarbonyl, (d-Ce) - Alkylaminocarbonyl, bis [(C 1 -C 6) -alkyl] aminocarbonyl, (C 1 -C 6) -alkyl [(C 1 -C 6) -alkyl] aminocarbonyl, (C 1 -C 6) -alkyl [(C 1 -C 6) -alkoxy] aminocarbonyl, (C 2 -C 6) ) - alkenylaminocarbonyl, (Ca-CeJ-cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (Ci-C6) -alkylaminocarbonyl,
A1 , A2, A3 und A4 gleich oder verschieden sind und unabhängig voneinander für N A 1 , A 2 , A 3 and A 4 are the same or different and are independently N
(Stickstoff) oder die Gruppierungen C-H, C-CH3, C-F, C-Cl, C-Br. C-l, C-OCF3, C-OCH3, C-CF3, C-CO2H, C-CO2CH3 stehen, wobei jedoch in keinem Fall mehr als zwei N-Atome benachbart sind, (Nitrogen) or the groups CH, C-CH 3 , CF, C-Cl, C-Br. Cl, C-OCF3, C-OCH3, C-CF 3, C-CO2H, C-CO2CH3 are, but in no case more than two N atoms are adjacent,
R17 und R18 unabhängig voneinander für Wasserstoff, Fluor, Chlor, Brom, lod, (Ci-Ce)- Alkyl, gegebenenfalls substituiertes Phenyl, Heteroaryl, Heterocyclyl, (Ca-Ce)- Cycloalkyl, (C2-C6)-Alkenyl, (C2-C6)-Alkinyl, (Ci-Ce)-Alkoxy, (Ci-Ce)-Alkoxy- (Ci-C6)-alkyl, Aryloxy-(Ci-C6)-alkyl, (Ci-C6)-Haloalkoxy, (Ci-C6)-Haloalkyl, R 17 and R 18 independently of one another represent hydrogen, fluorine, chlorine, bromine, iodine, (C 1 -C 6 ) -alkyl, optionally substituted phenyl, heteroaryl, heterocyclyl, (C 1 -C 6 ) -cycloalkyl, (C 2 -C 6 ) - Alkenyl, (C 2 -C 6 ) -alkynyl, (C 1 -C 6 ) -alkoxy, (C 1 -C 6 ) -alkoxy- (C 1 -C 6 ) -alkyl, aryloxy- (C 1 -C 6 ) -alkyl, C 6 ) -haloalkoxy, (C 1 -C 6 ) -haloalkyl,
(Ci-C6)-Haloalkoxy-(Ci-C6)-alkyl, (Ci-C6)-Alkoxy-(Ci-C6)-haloalkyl, (Ci-Ce)- Haloalkoxy-(Ci-C6)-haloalkyl, (CrC6)-Alkylthio, (Ci-C6)-Haloalkylthio, (Ci-C6)- Alkylthio-(Ci-C6)-alkyl, Hydroxycarbonyl, (d-CeJ-Alkoxycarbonyl, (C3-C6)- Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(CrC6)-alkoxycarbonyl, (C 1 -C 6 ) -haloalkoxy- (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -alkoxy- (C 1 -C 6 ) -haloalkyl, (C 1 -C 6 ) -haloalkoxy- (C 1 -C 6 ) - haloalkyl, (CrC 6) alkylthio, (Ci-C 6) haloalkylthio, (Ci-C 6) - alkylthio, (Ci-C6) alkyl, hydroxycarbonyl, (d-CeJ-alkoxy, (C3-C6) - Cycloalkoxycarbonyl, (C 3 -C 6) -cycloalkyl- (C 1 -C 6) -alkoxycarbonyl,
Aryloxycarbonyl, Aryl-(Ci-Cr,)-alkoxycarbonyl, (C2-C6)-Alkenyloxycarbonyl, (C2-C6)-Alkinyloxycarbonyl, Aminocarbonyl, (Ci-CeJ-Alkylaminocarbonyl, Bis[(d-C6)-alkyl]aminocarbonyl, (Ci-C6)-Alkyl[(CrC6)-Alkyl]aminocarbonyl, (Ci-C6)-Alkyl[(Ci-C6)-Alkoxy]aminocarbonyl, (C2-C6)-Alkenylaminocarbonyl, (C3-C6)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-Cf,)- alkylaminocarbonyl stehen,  Aryloxycarbonyl, aryl- (Ci-Cr,) -alkoxycarbonyl, (C2-C6) -alkenyloxycarbonyl, (C2-C6) -alkynyloxycarbonyl, aminocarbonyl, (Ci-CeJ-alkylaminocarbonyl, bis [(d-C6) -alkyl] aminocarbonyl, (C 1 -C 6) -alkyl [(C 1 -C 6) -alkyl] aminocarbonyl, (C 1 -C 6) -alkyl [(C 1 -C 6) -alkoxy] -aminocarbonyl, (C 2 -C 6) -alkenylaminocarbonyl, (C 3 -C 6) -cycloalkylaminocarbonyl, Arylaminocarbonyl, aryl- (Ci-Cf,) - alkylaminocarbonyl,
A5 für S (Schwefel), O (Sauerstoff) oder die Gruppierungen N-H, N-CH3, N-CH2CH3, N- CH(CH3)2, N-C02t-Bu, N-Aryl, N-Heteroaryl, N-Heterocyclyl steht, R19, R20, R23 und R24 unabhängig voneinander für Wasserstoff, (Ci-Ce)-Alkyl, Fluor, Chlor, Brom, lod, (C3-C6)-Cycloalkyl, gegebenenfalls substituiertes Phenyl,A 5 for S (sulfur), O (oxygen) or the groupings NH, N-CH 3 , N-CH 2 CH 3 , N-CH (CH 3 ) 2, N-CO 2 t-Bu, N-aryl, N-heteroaryl , N-heterocyclyl, R 19 , R 20 , R 23 and R 24 independently of one another represent hydrogen, (C 1 -C 6) -alkyl, fluorine, chlorine, bromine, iodine, (C 3 -C 6) -cycloalkyl, optionally substituted phenyl,
Heteroaryl, Heterocyclyl, (C2-Ce)-Alkenyl, Aryl-(d-C6)-alkyl, (Ci-Ce)-Alkoxy,Heteroaryl, heterocyclyl, (C 2 -C 6) -alkenyl, aryl- (C 1 -C 6) -alkyl, (C 1 -C 6) -alkoxy,
(Ci-C6)-Alkoxy-(Ci-C6)-alkoxy, (Ci-C6)-Alkoxy-(Ci-C6)-alkyl, Hydroxy, (Ci-C6)- Haloalkyl, (Ci-Cö)-Haloalkylthio stehen, (C 1 -C 6 ) -alkoxy- (C 1 -C 6 ) -alkoxy, (C 1 -C 6 ) -alkoxy- (C 1 -C 6 ) -alkyl, hydroxyl, (C 1 -C 6 ) -haloalkyl, Cö) haloalkylthio,
R19 und R23 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 19 and R 23 with the atoms to which they are attached form a completely saturated or partially saturated, optionally further substituted 5 to 7-membered ring,
A6, A7 gleich oder verschieden sind und unabhängig voneinander für O (Sauerstoff), S (Schwefel), N-H, N-OCH3, N-CH3 oder die Gruppierung CR21R22 stehen, wobei jedoch in keinem Fall zwei N-, O- oder S-Atome benachbart sind, und wobei R21 und R22 in der Gruppierung CR21R22 jeweils gleiche oder verschiedene A 6 , A 7 are the same or different and are each independently O (oxygen), S (sulfur), NH, N-OCH 3 , N-CH 3 or the group CR 21 R 22 , but in no case two N -, O or S atoms are adjacent, and wherein R 21 and R 22 in the group CR 21 R 22 are identical or different
Bedeutungen gemäß der nachstehenden Definition haben und  Have meanings as defined below and
R21 und R22 unabhängig voneinander für Wasserstoff, Fluor, Chlor, Brom, lod, (d-Co)- Alkyl, gegebenenfalls substituiertes Phenyl, Heteroaryl, Heterocyclyl, (Ca-Ce)- Cycloalkyl, (C2-Ce)-Alkenyl, (Ci-Cr,)-Alkoxy, (Ci-C6)-Alkoxy-(Ci-Cc,)-alkyl, R 21 and R 22 independently of one another represent hydrogen, fluorine, chlorine, bromine, iodine, (d-Co) -alkyl, optionally substituted phenyl, heteroaryl, heterocyclyl, (Ca-Ce) -cycloalkyl, (C 2 -C 6) -alkenyl, (Ci-Cr,) - alkoxy, (Ci-C6) -alkoxy- (Ci-Cc,) - alkyl,
(Ci-C6)-Haloalkoxy, (Ci-C6)-Haloalkyl, (Ci-C6)-Alkylthio, (Ci-Ce)-Haloalkylthio,(C 1 -C 6 ) -haloalkoxy, (C 1 -C 6 ) -haloalkyl, (C 1 -C 6 ) -alkylthio, (C 1 -C 6 ) -haloalkylthio,
(Ci-Cc>)-Alkylthio-(Ci-C6)-alkyl, Hydroxycarbonyl, (Ci-Cc>)-Alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci-C6)-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-Co)-alkoxycarbonyl, (C2-C6)-Alkenyloxycarbonyl, (C2-C6)-Alkinyloxycarbonyl, Aminocarbonyl, (Ci-C6)-Alkylaminocarbonyl, Bis[(CrC6)-alkyl]aminocarbonyl, (Ci-C6)-Alkyl[(CrC6)-Alkyl]aminocarbonyl,(Ci-Cc > ) -alkylthio (Ci-C6) -alkyl, hydroxycarbonyl, (Ci-Cc > ) alkoxycarbonyl, (C3-C6) -cycloalkoxycarbonyl, (C3-C6) -cycloalkyl- (Ci-C6) - alkoxycarbonyl, aryloxycarbonyl, aryl- (C 1 -C 6) -alkoxycarbonyl, (C 2 -C 6) -alkenyloxycarbonyl, (C 2 -C 6) -alkynyloxycarbonyl, aminocarbonyl, (C 1 -C 6) -alkylaminocarbonyl, bis [(C 1 -C 6) -alkyl] -aminocarbonyl, (Ci-C6) alkyl [(CRC6) alkyl] aminocarbonyl,
(CrC6)-Alkyl[(Ci-C6)-Alkoxy]aminocarbonyl, (C2-C6)-Alkenylaminocarbonyl, (C3-C6)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-Ce)- alkylaminocarbonyl, Amino, (Ci-C6)-Alkylamino, (Ca-CeJ-Cycloalkylamino, Bis- [(Ci-C6)-Alkyl]amino stehen, (C 1 -C 6) -alkyl [(C 1 -C 6) -alkoxy] -aminocarbonyl, (C 2 -C 6) -alkenylaminocarbonyl, (C 3 -C 6) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 6) -alkylaminocarbonyl, amino, (C 1 -C 6 ) -Alkylamino, (Ca-CeJ-cycloalkylamino, bis- [(Ci-C6) -alkyl] -amino,
R25, R26, R28 und R29 unabhängig voneinander für Wasserstoff, (Ci-Ce)-Alkyl, Fluor, Chlor, Brom, lod, (Ca-Ce-Cycloalkyl, Aryl, Heteroaryl, Heterocyclyl, (C2-C6)- Alkenyl, Aryl-(Ci-C6)-alkyl, (Ci-C6)-Alkoxy. (Ci-C6)-Haloalkyl stehen, A8 für O (Sauerstoff), S (Schwefel), N-H, N-CH3, N-OCH3 oder die Gruppierung CHR27 steht und wobei R27 in der Gruppierung CHR27 die Bedeutung gemäß der nachstehenden Definition hat, R 25 , R 26 , R 28 and R 29 independently of one another represent hydrogen, (C 1 -C 6) -alkyl, fluorine, chlorine, bromine, iodine, (C 1 -C 6 -cycloalkyl, aryl, heteroaryl, heterocyclyl, (C 2 -C 6) Alkenyl, aryl- (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -alkoxy. (C 1 -C 6 ) -haloalkyl, A 8 is O (oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the moiety CHR 27 , and wherein R 27 in the moiety CHR 27 has the meaning as defined below,
R27 für Wasserstoff, Fluor, Chlor, Brom, lod, (Ci-Ce)-Alkyl, gegebenenfalls R 27 is hydrogen, fluorine, chlorine, bromine, iodine, (C 1 -C 6) -alkyl, if appropriate
substituiertes Phenyi, Heteroaryi, Heterocyclyl, (C3-C6)-Cycloalkyl, (C2-C6)- Alkenyl, (CrC6)-Alkoxy, (CrCö)-Haloalkoxy, (Ci-C6)-Haloalkyl, (CrC6)-Alkylthio, (d-CeJ-Haloalkylthio, Hydroxycarbonyi, (Ci-C-6)-Alkoxycarbonyl, (Ca-Ce)- Cycloalkoxycarbonyl, Aryl-(Ci-C6)-alkoxycarbonyl, (C2-C6)-Alkenyloxycarbonyl, (C2-Cr>)-Alkinyloxycarbonyl, Aminocarbonyl, (Ci-C6)-Alkylaminocarbonyl, Bis[(CrC6)-alkyl]aminocarbonyl, (CrC6)-Alkyl[(Ci-C6)-Alkyl]aminocarbonyl, (Ci-C6)-Alkyl[(Ci-C6)-Alkoxy]aminocarbonyl, (C2-C6)-Alkenylaminocarbonyl, (C3-C6)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(C i-CG)- alkylaminocarbonyl, Amino, (Ci-C-6)-Alkylamino, (Ca-CeJ-Cycloalkylamino, Bis- [(Ci-C6)-Alkyl]amino steht, substituted phenyl, heteroaryl, heterocyclyl, (C3-C6) cycloalkyl, (C2-C6) - alkenyl, (CrC 6) alkoxy, (CrCö) haloalkoxy, (Ci-C 6) -haloalkyl, (CrC 6) - Alkylthio, (d-CeJ-haloalkylthio, hydroxycarbonyl, (C 1 -C 6) -alkoxycarbonyl, (C 1 -C 6) -cycloalkoxycarbonyl, aryl- (C 1 -C 6) -alkoxycarbonyl, (C 2 -C 6) -alkenyloxycarbonyl, (C 2 -C 6) -alkoxycarbonyl) Cr > ) alkynyloxycarbonyl, aminocarbonyl, (C 1 -C 6) -alkylaminocarbonyl, bis [(C 1 -C 6) -alkyl] aminocarbonyl, (C 1 -C 6) -alkyl [(C 1 -C 6) -alkyl] aminocarbonyl, (C 1 -C 6) -alkyl [ (C 1 -C 6) -alkoxy] -aminocarbonyl, (C 2 -C 6) -alkenylaminocarbonyl, (C 3 -C 6) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 4) -alkylaminocarbonyl, amino, (C 1 -C 6) -alkylamino , (Ca-CeJ-cycloalkylamino, bis- [(C 1 -C 6 ) -alkyl] -amino,
R30, R31 , R32, R34, R35 und R36 unabhängig voneinander für Wasserstoff, (CrC6)-Alkyl, Halogen, (C3-C6)-Cycloalkyl, Aryl, Heteroaryi, Heterocyclyl, (C2-Ce)-Alkenyl, (Ci-C6)-Alkoxy, (Ci-C6)-Haloalkyl, (Ci-Ce)-Alkylthio, (Ci-C6)-Haloalkylthio stehen, R 30 , R 31 , R 32 , R 34 , R 35 and R 36 independently of one another represent hydrogen, (C 1 -C 6 ) -alkyl, halogen, (C 3 -C 6 ) -cycloalkyl, aryl, heteroaryl, heterocyclyl, (C 2 -C 6) Alkenyl, (C 1 -C 6 ) -alkoxy, (C 1 -C 6 ) -haloalkyl, (C 1 -C 6 ) -alkylthio, (C 1 -C 6 ) -haloalkylthio,
A9 für O (Sauerstoff), S (Schwefel), N-H, N-CH3, N-OCH3 oder die Gruppierung CHR33 steht und wobei R33 in der Gruppierung CHR33 die Bedeutung gemäß der nachstehenden Definition hat und A 9 is O (oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the group CHR 33 , and wherein R 33 in the group CHR 33 has the meaning as defined below and
R33 für Wasserstoff, Fluor, Chlor, Brom, lod, (Ci-Ce)-Alkyl, gegebenenfalls R 33 represents hydrogen, fluorine, chlorine, bromine, iodine, (C 1 -C 6) -alkyl, if appropriate
substituiertes Phenyi, Heteroaryi, Heterocyclyl, (C3-C-6)-Cycloalkyl, (C2-C6)- Alkenyl, (Ci-C6)-Alkoxy, (Ci-C6)-Alkoxy-(Ci-C6)-alkyl, (Ci-Cr>)-Haloalkoxy, substituted phenyl, heteroaryl, heterocyclyl, (C 3 -C 6) -cycloalkyl, (C 2 -C 6) -alkenyl, (C 1 -C 6) -alkoxy, (C 1 -C 6 ) -alkoxy- (C 1 -C 6 ) -alkyl, (Ci-Cr>) -haloalkoxy,
(Ci-C6)-Haloalkyl, (Ci-C6)-Alkylthio, (Ci-Cö)-Haloalkylthio, Hydroxycarbonyi, (d-C6)-Alkoxycarbonyl, (C3-Cr>)-Cycloalkoxycarbonyl, Aryl-(Ci-Ce)- alkoxycarbonyl, (C2-C6)-Alkenyloxycarbonyl, (C2-C6)-Alkinyloxycarbonyl, Aminocarbonyl, (Ci-C6)-Alkylaminocarbonyl, Bis[(d-C6)-alkyl]aminocarbonyl, (Ci-C6)-Alkyl[(Ci-C6)-Alkyl]aminocarbonyl, (Ci-C6)-Alkyl[(Ci-C6)- Alkoxy]aminocarbonyl, (C2-C6)-Alkenylaminocarbonyl, (C3-Ce)- Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C6)-alkylaminocarbonyl, Amino, (CrC6)-Alkylamino, (C3-C6)-Cycloalkylamino, Bis-[(Ci-C6)-Alkyl]amino steht, R37 für (Ci-Co)-Alkyl, gegebenenfalls substituiertes Phenyl, Heteroaryl, Heterocyclyl,(Ci-C 6) -haloalkyl, (Ci-C 6) alkylthio, (Ci-COE) haloalkylthio, Hydroxycarbonyi, (d-C6) alkoxycarbonyl, (C3-Cr>) -cycloalkoxycarbonyl, aryl (Ci- Ce) alkoxycarbonyl, (C 2 -C 6 ) -alkenyloxycarbonyl, (C 2 -C 6 ) -alkynyloxycarbonyl, aminocarbonyl, (C 1 -C 6) -alkylaminocarbonyl, bis [(C 1 -C 6 ) -alkyl] aminocarbonyl, (C 1 -C 6 ) Alkyl [(C 1 -C 6 ) -alkyl] aminocarbonyl, (C 1 -C 6 ) -alkyl [(C 1 -C 6 ) -alkoxy] -aminocarbonyl, (C 2 -C 6) -alkenylaminocarbonyl, (C 3 -Ce) - Cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 6) -alkylaminocarbonyl, amino, (C 1 -C 6) -alkylamino, (C 3 -C 6) -cycloalkylamino, bis- [(C 1 -C 6) -alkyl] -amino, R 37 represents Co) -alkyl, optionally substituted phenyl, heteroaryl, heterocyclyl,
(C3-C6)-Cycloalkyl, (C2-C6)-Alkenyl, (Ci-Ce)-Alkoxy, (Ci-C6)-Alkoxy-(Ci-C6)-alkyl, Aryloxy-(Ci-C-6)-alkyl, (Ci-C6)-Alkoxycarbonyl, (Ca-Ce)- Cycloalkoxycarbonyl, Aryl-(d-C6)-alkoxycarbonyl, (C2-C6)-Alkenyloxycarbonyl, (C2-C-6)- Alkinyloxycarbonyl, (Ci-Cö)-Alkylcarbonyl, (C3-Ce)-Cycloalkylcarbonyl, (C 3 -C 6) -cycloalkyl, (C 2 -C 6) alkenyl, (Ci-Ce) alkoxy, (Ci-C6) alkoxy (Ci-C 6) alkyl, aryloxy (C -C-6) -alkyl, (Ci-C6) -alkoxycarbonyl, (Ca-Ce) - cycloalkoxycarbonyl, aryl- (d-C6) -alkoxycarbonyl, (C2-C6) -alkenyloxycarbonyl, (C2-C-6) - Alkynyloxycarbonyl, (C 1 -C 6) -alkylcarbonyl, (C 3 -C 6) -cycloalkylcarbonyl,
Arylcarbonyl, Heteroarylcarbonyl steht.  Arylcarbonyl, heteroarylcarbonyl.
Besonders bevorzugt sind Verbindungen der allgemeinen Formel (I), die durch die Formeln (la) bis (lo) beschrieben werden, Particular preference is given to compounds of the general formula (I) which are described by the formulas (Ia) to (Io)
worin [X-Y] für die Gruppierung where [X-Y] is the grouping
[x-ΥΓ steht, für die Gruppierungen Q-1 bis Q-6 [x-ΥΓ stands for the groupings Q-1 to Q-6
Q-1 Q-2 Q-3  Q-1 Q-2 Q-3
Q-4 ; Q-5 und Q-6 steht, wobei R13, R 4, R15, R16, R17, R18, R19, R20, R23, R24, R25, R26, R28, R29, R30, R31, R32, R34, R35 und R36 sowie A1 bis A9 jeweils die Bedeutung gemäß der nachstehenden Definitionen haben und wobei der Pfeil für eine Bindung zur jeweiligen Gruppierung C-R6 in den vorgenannten Formeln (la) bis (lo) steht, Q-4 ; Q -5 and Q -6 wherein R 13 , R 4 , R 15 , R 16 , R 17 , R 18 , R 19 , R 20 , R 23 , R 24 , R 25 , R 26 , R 28 , R 29 , R 30 , R 31 , R 32 , R 34 , R 35 and R 36 and A 1 to A 9 each have the meaning according to the have the following definitions and wherein the arrow for a bond to the respective grouping CR 6 is in the abovementioned formulas (Ia) to (Io),
R5 für Hydroxy, (d-CeJ-Alkoxy, Aryioxy, (Ca-CeJ-Cycloalkyloxy, (C2-C-6)-Alkenyloxy, (C2-C6)-Alkenyl-(Ci-C6)-alkyloxy, (Ci-C6)-Alkoxy-(Ci-C6)-alkyloxy, (Ci-Ce)- Alkylcarbonyloxy, Arylcarbonyloxy, Heteroarylcarbonyloxy, (Ca-Ce)- Cycloalkylcarbonyloxy, (d-Cr -Alkoxycarbonyloxy, (C2-Ce)- Alkenyloxycarbonyloxy, Aryloxy-(Ci-C6)-alkyloxy, Aryl-(Ci-C6)-alkyloxy, (d-Ce)- Alkoxy-(Ci-C6)-alkoxy-(Ci-C6)-alkyloxy, (Ci-C6)-Alkylthio-(Ci-C6)-alkyloxy, Tris[(Ci-C6)-alkyl]silyloxy, (Ci-C6)-Alkyl-Bis[(Ci-C6)-alkyl]silyloxy, (Ci-Ce)-Alkyl- bis(Aryl)silyloxy, Aryl-bis[(CrCc>)— alkyljsilyloxy, Cycloalkyl-bis[(d-C6)- alkyl]silyloxy, Halo-bis[(Ci-C6)-alkyl]silyloxy, Tris[(Ci-C6)-alkyl]silyl-(Ci-C6)- alkoxy-(Ci-C6)-alkyloxy, steht, R 5 is hydroxy, (d-CeJ) alkoxy, aryloxy, (C 1 -C 12 -cycloalkyloxy, (C 2 -C 6) -alkenyloxy, (C 2 -C 6 ) -alkenyl- (C 1 -C 6 ) -alkyloxy, ( C 1 -C 6 -alkoxy- (C 1 -C 6 ) -alkyloxy, (C 1 -C 6 ) -alkylcarbonyloxy, arylcarbonyloxy, heteroarylcarbonyloxy, (C 1 -C 6 ) -cycloalkylcarbonyloxy, (C 1 -C 6 -alkoxycarbonyloxy, (C 2 -C 6 ) - Alkenyloxycarbonyloxy, aryloxy- (C 1 -C 6 ) -alkyloxy, aryl- (C 1 -C 6 ) -alkyloxy, (d-Ce) -alkoxy- (C 1 -C 6 ) -alkoxy- (C 1 -C 6 ) -alkyloxy, (Ci -C 6) -alkylthio (C 1 -C 6 ) -alkyloxy, tris [(C 1 -C 6 ) -alkyl] silyloxy, (C 1 -C 6 ) -alkyl bis [(C 1 -C 6 ) -alkyl] silyloxy, (Ci -Ce) -alkyl bis (aryl) silyloxy, aryl bis [(CrCc) alkyl] silyloxy, cycloalkyl bis [(d-C6) alkyl] silyloxy, halo bis [(Ci-C 6 ) alkyl] silyloxy, tris [(C 1 -C 6 ) alkyl] silyl (C 1 -C 6 ) alkoxy (C 1 -C 6 ) alkyloxy,
R6 für (Ci-C6)-Alkylsulfonylaminocarbonyl, (Ca-Ce)-R 6 is (C 1 -C 6 ) -alkylsulfonylaminocarbonyl, (Ca-Ce) -
Cycloalkylsulfonylaminocarbonyl, Hydroxycarbonyl, (Ci-Cc)-Alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(CrC6)-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C6)-alkoxycarbonyl, (C2-C6)-Alkenyloxycarbonyl, (C2-C6)-Alkinyloxycarbonyl, (Ci-C6)-Haloalkyloxycarbonyl, (Ci-C6)-Alkoxy- (Ci-Ce)-alkoxycarbonyl, (C2-Cö)-Alkenyloxy-(Ci-C6)-alkoxycarbonyl, (Ci-Ce)- Alkylamino-(Ci-C6)-alkoxycarbonyl, Ths[(Ci-C6)-alkyl]silyloxy-(CrC6)- alkoxycarbonyl, Bis[(Ci-C6)-Alkyl]amino-(CrQ;)-alkoxycarbonyl, (Ci-Ce)- Alkyl[(CrC6)-alkyl]amino-(Ci-C6)-alkoxycarbonyl, Cyano-(CrCö)- alkoxycarbonyl, Heterocyclyl-N-(Ci-C6)-alkoxycarbonyl, Heteroaryloxycarbonyl, Heteroaryl-(Ci-C6)-alkoxycarbonyl, Heterocyclyl-(Ci-C6)-alkoxycarbonyl, Heterocyclyloxycarbonyl, (C2-C6)-Alkenyl-(CrC6)-alkoxycarbonyl, (C2-Ce)- Alkinyl-(Ci-C6)-alkoxycarbonyl, Aryl-(C2-C6)-alkinyloxycarbonyl, Aryl-(C2-Ce)- alkenyloxycarbonyl, Aminocarbonyl, (Ci-Cc -Alkylaminocarbonyl, Bis[(Ci-Cc>)- alkyljaminocarbonyl, (Ci-C6)-Alkyl[(Ci-C6)-Alkyl]aminocarbonyl, (Ci-Ce)- Alkyl[(Ci-C6)-Alkoxy]aminocarbonyl, (C2-C6)-Alkenylaminocarbonyl, (C Ce)- Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-Ce)-alkylaminocarbonyl, Heteroaryl-(CrC6)-alkylaminocarbonyl, Cyano-(d-C6)-alkylaminocarbonyl, (Ci-Cc>)-Haloalkylaminocarbonyl, (C2-C6)-Alkinyl-(d-C6)-alkylaminocarbonyl, (Ci-C6)-Alkoxycarbonylaminocarbonyl, Aryl-(Ci-Cr,)- alkoxycarbonylaminocarbonyl, Hydroxycarbonyl-(Ci-C6)-alkyl, (Ci-Ce)- Alkoxycarbonyl-(CrC6)-alkyl, (C3-C6)-Cycloalkoxycarbonyl-(Ci-C6)-alkyl, (C3-C6)-Cycloaikyl-(Ci-C6)-alkoxycarbonyl-(Ci-C6)-alkyl. (C2-C6)- Alkenyloxycarbonyl-(CrC6)-alkyl, Aryl-(Ci-Ce)-alkoxycarbonyl-(Ci-C6)-alkyl, (Ci-C6)-Alkylaminocarbonyl-(Ci-C6)-alkyl, Aminocarbonyl-(Ci-C6)-alkyl, Cycloalkylsulfonylaminocarbonyl, hydroxycarbonyl, (Ci-Cc) -alkoxycarbonyl, (C3-C6) -cycloalkoxycarbonyl, (C3-C6) -cycloalkyl- (CrC6) -alkoxycarbonyl, aryloxycarbonyl, aryl- (Ci-C6) -alkoxycarbonyl, (C2-C6 ) Alkenyloxycarbonyl, (C 2 -C 6) -alkynyloxycarbonyl, (C 1 -C 6) -haloalkyloxycarbonyl, (C 1 -C 6) -alkoxy- (C 1 -C 6) -alkoxycarbonyl, (C 2 -C 6) -alkenyloxy- (C 1 -C 6) - alkoxycarbonyl, (Ci-Ce) - alkylamino- (Ci-C6) -alkoxycarbonyl, Ths [(Ci-C6) -alkyl] silyloxy- (CrC6) -alkoxycarbonyl, bis [(Ci-C6) -alkyl] amino- (CrQ ;) - alkoxycarbonyl, (C 1 -C 6) -alkyl [(C 1 -C 6) -alkyl] amino- (C 1 -C 6) -alkoxycarbonyl, cyano- (C 1 -C 4) -alkoxycarbonyl, heterocyclyl-N- (C 1 -C 6) -alkoxycarbonyl, heteroaryloxycarbonyl , Heteroaryl- (C 1 -C 6) -alkoxycarbonyl, heterocyclyl- (C 1 -C 6) -alkoxycarbonyl, heterocyclyloxycarbonyl, (C 2 -C 6) -alkenyl- (C 1 -C 6) -alkoxycarbonyl, (C 2 -C 6) -alkynyl- (C 1 -C 6) -alkoxycarbonyl, aryl- (C 2 -C 6) -alkynyloxycarbonyl, aryl- (C 2 -C 6) -alkenyloxycarbonyl, aminocarbonyl, (C 1 -C 6 -alkylaminocarbonyl, bis [(C 1 -C 4) -alkyl] -aminocarbonyl, (C 1 -C 6) -alkyl [(Ci-C6) -Al kyl] aminocarbonyl, (Ci-Ce) - alkyl [(Ci-C6) -alkoxy] aminocarbonyl, (C2-C6) alkenylaminocarbonyl, (C Ce) - cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (Ci-Ce) -alkylaminocarbonyl, heteroaryl - (CRC6) alkylaminocarbonyl, cyano (d-C6) alkylaminocarbonyl, (C Cc>) -Haloalkylaminocarbonyl, (C2-C6) alkynyl (d-C6) alkylaminocarbonyl, (C-C6) -Alkoxycarbonylaminocarbonyl, aryl (C Cr) - alkoxycarbonylaminocarbonyl, hydroxycarbonyl- (C 1 -C 6) -alkyl, (C 1 -C 6) -alkoxycarbonyl- (C 1 -C 6) -alkyl, (C 3 -C 6) -cycloalkoxycarbonyl- (C 1 -C 6) -alkyl, (C 3 -C 6) -cycloacyl- (C 1 -C 6 ) -alkoxycarbonyl- (C 1 -C 6 ) -alkyl. (C 2 -C 6 ) -alkenyloxycarbonyl- (C 1 -C 6 ) -alkyl, aryl- (C 1 -C 6 ) -alkoxycarbonyl- (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -alkylaminocarbonyl- (C 1 -C 6 ) -alkyl, aminocarbonyl (Ci-C6) alkyl,
Bis[(Ci-C6)-alkyl]aminocarbonyl-(Ci-C6)-alkyl, (C3-C6)-Cycloalkylaminocarbonyl- (Ci-C6)-alkyl, Aryl-(Ci-C6)-alkylaminocarbonyl-(Ci-C6)-alkyl, Heteroaryl-(CrC6)- alkylaminocarbonyl-(Ci-C6)-alkyl, Cyano-(Ci-C6)-alkylaminocarbonyl-(Ci-C6)- alkyl, (Ci-C6)-Haioalkylaminocarbonyl-(Ci-C6)-alkyl, (C2-C6)-Alkinyl-(Ci-C6)- alkylaminocarbonyl-(Ci-C6)-alkyl, (C3-C6)-Cycloalkyl-(Ci-C6)- alkylaminocarbonyl-(Ci-C6)-alkyl, (Ci-Cö)-Alkoxycarbonylaminocarbonyl- (Ci-Cc>)-alkyl, Aryl-(Ci-C6)-alkoxycarbonylaminocarbonyl-(Ci-C6)-alkyl, (Ci-Ce)- Alkoxycarbonyl-(Ci-C6)-alkylaminocarbonyl, Hydroxycarbonyl-(Ci-C6)- alkylaminocarbonyl, Aryl-(Ci-C6)-alkoxycarbonyl-(Ci-C6)-alkylaminocarbonyl, Aminocarbonyl-(Ci-C6)-alkylaminocarbonyl, (Ci-CeJ-Alkylaminocarbonyl- (CrCe alkylaminocarbonyL Bis [(C 1 -C 6 ) -alkyl] aminocarbonyl- (C 1 -C 6 ) -alkyl, (C 3 -C 6 ) -cycloalkylaminocarbonyl- (C 1 -C 6 ) -alkyl, aryl- (C 1 -C 6 ) -alkylaminocarbonyl- (Ci -C 6) -alkyl, heteroaryl- (C 1 -C 6 ) -alkylaminocarbonyl- (C 1 -C 6 ) -alkyl, cyano- (C 1 -C 6 ) -alkylaminocarbonyl- (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -haloalkylaminocarbonyl- C 1 -C 6 ) -alkyl, (C 2 -C 6 ) -alkynyl- (C 1 -C 6 ) -alkylaminocarbonyl- (C 1 -C 6 ) -alkyl, (C 3 -C 6 ) -cycloalkyl- (C 1 -C 6 ) -alkylaminocarbonyl- (Ci-C6) alkyl, (Ci-Cö) alkoxycarbonylaminocarbonyl (Ci-Cc > ) alkyl, aryl (Ci-C6) -alkoxycarbonylaminocarbonyl (Ci-C6) -alkyl, (Ci-Ce) - Alkoxycarbonyl (C 1 -C 6) -alkylaminocarbonyl, hydroxycarbonyl- (C 1 -C 6) -alkylaminocarbonyl, aryl- (C 1 -C 6) -alkoxycarbonyl- (C 1 -C 6) -alkylaminocarbonyl, aminocarbonyl- (C 1 -C 6) -alkylaminocarbonyl, (C 1 -C 4) -alkylaminocarbonyl, CeJ-alkylaminocarbonyl (CrCe alkylaminocarbonyL
(C3-C6)-Cycloalkylaminocarbonyl-(Ci-Cö)-alkylaminocarbonyl, (Cs-Ce)- Cycloalkyl-(Ci-C6)-alkylaminocarbonyl, (C3-C6)-Cycloalkyl-(Ci-C6)- alkylaminocarbonyl-(Ci-C6)-alkyl, (C3-C6)-Cycloalkyl-(Ci-C6)- alkylaminocarbonyl-(Ci-C6)-alkylaminocarbonyl, (C2-Cö)-Alkenyl-(Ci-C6)- alkylaminocarbonyl, (C2-C6)-Alkenylaminocarbonyl-(Ci-Cö)-alkyl, (C2-Ce)- Alkenyl-(Ci-C6)-alkylaminocarbonyl-(CrC6)-alkyi, (Ci-C6)-Alkylcarbonyl, (Ca-Cr,)- Cycioalkylcarbonyl, Arylcarbonyl, Formyl, Hydroxyiminomethyl, (C 3 -C 6 ) -cycloalkylaminocarbonyl- (C 1 -C 6 ) -alkylaminocarbonyl, (Cs-Ce) -cycloalkyl- (C 1 -C 6 ) -alkylaminocarbonyl, (C 3 -C 6 ) -cycloalkyl- (C 1 -C 6 ) -alkylaminocarbonyl (C 1 -C 6 ) -alkyl, (C 3 -C 6 ) -cycloalkyl- (C 1 -C 6 ) -alkylaminocarbonyl- (C 1 -C 6 ) -alkylaminocarbonyl, (C 2 -C 6 ) -alkenyl- (C 1 -C 6 ) - alkylaminocarbonyl, (C 2 -C 6) -alkenylaminocarbonyl (C 1 -C 6) -alkyl, (C 2 -C 6) -alkenyl- (C 1 -C 6) -alkylaminocarbonyl- (C 1 -C 6) -alkyl, (C 1 -C 6) -alkylcarbonyl, (Ca -Cr,) - cycloalkylcarbonyl, arylcarbonyl, formyl, hydroxyiminomethyl,
Aminoiminomethyl, (Ci-C6)-Alkoxyiminomethyl, (Ci-CeJ-Alkylaminoiminomethyl, Bis[(Ci-C6)-alkyl]aminoiminomethyl, (C3-C6)-Cycloalkoxyiminomethyl, (Ca-Ce)- Cycloalkyl-(Ci-C6)-alkoximinomethyl, Aryloximinomethyl, Aryl-(d-C6)- alkoxyiminomethyl, Aryl-(Ci-C6)-alkylaminoiminomethyl, (C2-C-6)- Alkenyloxyiminomethyl, Arylaminoiminomethyl, Arylsulfonylaminoiminomethyl, Hydroxycarbonylheterocyclyl-(Ci-C6)-alkyl, (Ci-C6)-Alkoxycarbonylheterocyclyl- (CrC6)-alkyl, Hydroxycarbonyl-(C3-C6)-cycloalkyl-(Ci-C6)-alkyl, (d-Ce)- Alkoxycarbonyl-(C3-C6)-cycloalkyl-(Ci-C6)-alkyl, Hydroxyaminocarbonyl, Aminoiminomethyl, (C 1 -C 6) -alkoxyiminomethyl, (C 1 -C 6 -alkylaminoiminomethyl, bis [(C 1 -C 6) -alkyl] aminoiminomethyl, (C 3 -C 6) -cycloalkoxyiminomethyl, (C 2 -C 6) -cycloalkyl- (C 1 -C 6) -alkoximinomethyl, aryloximinomethyl, aryl- (d-C6) -alkoxyiminomethyl, aryl- (Ci-C6) -alkylaminoiminomethyl, (C2-C-6) -alkenyloxyiminomethyl, arylaminoiminomethyl, arylsulfonylaminoiminomethyl, hydroxycarbonylheterocyclyl- (Ci-C6) -alkyl, ( C 1 -C 6 ) -alkoxycarbonylheterocyclyl- (C 1 -C 6 ) -alkyl, hydroxycarbonyl- (C 3 -C 6 ) -cycloalkyl- (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -alkoxycarbonyl- (C 3 -C 6 ) -cycloalkyl) (C 1 -C 6) -alkyl, hydroxyaminocarbonyl,
(Ci-C6)-Alkoxyaminocarbonyl, Aryl-(CrC6)-alkoxyaminocarbonyl, (d-Ce)- Alkoxycarbonyl-heterocyclyl-N-carbonyl, (Ci-Cr>)-Alkoxycarbonyl-(Ci-C6)-alkyl- heterocyclyiidenaminocarbonyl, (CrC6)-Alkoxycarbonylheterocyclyliden-(Ci-C6)- alkylaminocarbonyl, (Ci-C6)-Alkoxycarbonyl-(Ci-C6)-Alkyl((Ci-C-6)- alkyl)aminocarbonyl, (Ci-C6)-Alkoxycarbonyl-(C3-C6)- cycloalkylidenaminocarbonyl, Heterocyclyl-N-carbonyL (Ci-C6)-Alkoxy-(Ci-C6)- alkylaminocarbonyl steht, (Ci-C6) alkoxyaminocarbonyl, aryl (CRC6) alkoxyaminocarbonyl, (d-Ce) - alkoxycarbonyl-heterocyclyl-N-carbonyl, (Ci-Cr>) alkoxycarbonyl (Ci-C6) alkyl heterocyclyiidenaminocarbonyl, ( CRC6) -Alkoxycarbonylheterocyclyliden- (Ci-C6) - alkylaminocarbonyl, (C 1 -C 6) -alkoxycarbonyl- (C 1 -C 6) -alkyl ((C 1 -C 6) -alkyl) aminocarbonyl, (C 1 -C 6) -alkoxycarbonyl- (C 3 -C 6) -cycloalkylideneaminocarbonyl, heterocyclyl-N- carbonyl (C 1 -C 6) alkoxy- (C 1 -C 6) -alkylaminocarbonyl,
R13, R14, R15 und R16 unabhängig voneinander für Wasserstoff, Fluor, Chlor, Brom, lod, Nitro, Amino, Cyano, (C1-C5)- Alkyl, gegebenenfalls substituiertes Phenyl, Heteroaryl, (C3-C6)-Cycloalkyl, (C4-C6)-Cycloalkenyl, (C2-C5)-Alkenyl, (C2-C5)- Alkinyl, (C2-C5)-Alkenyl-(Ci-C5)-alkyl, (C2-C5)-Alkinyl-(Ci-C5)-alkyl, Hydroxy, (Ci-C5)-Alkoxy, (Ci-C5)-Alkoxy-(Ci-C5)-alkoxy, (Ci-C5)-Alkoxy-(Ci-C5)-alkyl, Hydroxy-(Ci-C5)-alkyl, (CrC5)-Haloalkoxy, (CrC5)-Haloalkyl, (C2-C5)- Haloalkenyl, (C2-C5)-Haloalkinyl, (Ci-C5)-Haloalkoxy-(Ci-C5)-alkyl, (C1-C5)- Alkoxy-(Ci-C5)-haloalkyl, (Ci-C5)-Haloalkoxy-(Ci-C5)-haloalkyl, Hydrothio, (CrC5)-Alkylthio, (CrC5)-Haloalkylthio, (Ci-Cr>)-Alkylthio-(Ci-C5)-alkyl, (C1-C5)- Haloalkylthio-(CrC5)-alkyl, (Ci-C5)-Alkylamino, Bis-[(Ci-C5)-alkyl]amino, (C2-C5)-Alkenylamino, (Ca-Ce Cycloalkylamino, (Ci-Cr>)-Alkylcarbonylamino, (C3-C6)-Cycloalkylcarbonylamino, Arylcarbonylamino, Heteroarylcarbonylamino, Formylamino, (Ci-C5)-Haloalkylcarbonylamino, (Ci-C5)-Alkoxycarbonylamino, (Ci-C5)-Alkylaminocarbonylamino, (C1-C5)- Alkyl[(Ci-Cs)- Alkyljaminocarbonylamino, (Ci-Cr>)-Alkylsulfonylamino, (Ca-Ce)- Cycloalkylsulfonylamino, Arylsulfonylamino, Hetarylsulfonylamino, Sulfonyl- (Ci-C5)-haloalkylamino, Amino-(CrC5)-alkylsulfonyl, Amino-(Ci-C5)- haloalkylsulfonyl, (Ci-C5)-Alkylaminosulfonyl, Bis[(Ci-Cr,)-alkyl]aminosulfonyl, (Ca-Ce Cycloalkylaminosulfonyl, (Ci-C5)-Haloalkylaminosulfonyl, R 13 , R 14 , R 15 and R 16 independently of one another represent hydrogen, fluorine, chlorine, bromine, iodine, nitro, amino, cyano, (C 1 -C 5 ) -alkyl, optionally substituted phenyl, heteroaryl, (C 3 -C 6 ) Cycloalkyl, (C 4 -C 6 ) cycloalkenyl, (C 2 -C 5 ) alkenyl, (C 2 -C 5 ) alkynyl, (C 2 -C 5 ) alkenyl (C 1 -C 5 ) alkyl , (C 2 -C 5 ) -alkynyl (C 1 -C 5 ) -alkyl, hydroxy, (C 1 -C 5 ) -alkoxy, (C 1 -C 5 ) -alkoxy- (C 1 -C 5 ) -alkoxy, (Ci -C 5) alkoxy (Ci-C 5) alkyl, hydroxy (Ci-C 5) alkyl, (CrC 5) -haloalkoxy, (CrC 5) haloalkyl, (C2-C5) - haloalkenyl, ( C 2 -C 5) haloalkynyl, (Ci-C 5), haloalkoxy (Ci-C 5) alkyl, (C1-C5) - alkoxy (Ci-C5) haloalkyl, (Ci-C 5) haloalkoxy (Ci-C5) haloalkyl, Hydrothio, (CrC 5) alkylthio, (CrC 5) haloalkylthio, (Ci-Cr>) alkylthio (Ci-C5) alkyl, (C1-C5 ) - haloalkylthio (C 1 -C 5 ) -alkyl, (C 1 -C 5 ) -alkylamino, bis - [(C 1 -C 5 ) -alkyl] -amino, (C 2 -C 5 ) -alkenylamino, (C 1 -C 6 -cycloalkylamino, (Ci cr>) alkylcarbonylamino, (C3-C6) -Cycloalkylcarbonylamino, arylcarbonylamino, Heteroarylcarbonylam ino, formylamino, (C 1 -C 5) -haloalkylcarbonylamino, (C 1 -C 5) -alkoxycarbonylamino, (C 1 -C 5) -alkylaminocarbonylamino, (C 1 -C 5) -alkyl [(C 1 -C 5) -alkyl] -aminocarbonylamino, (C 1 -C 8 -cr>) Alkylsulfonylamino, (Ca-Ce) -cycloalkylsulfonylamino, arylsulfonylamino, hetarylsulfonylamino, sulfonyl- (C 1 -C 5) -haloalkylamino, amino- (C 1 -C 5) -alkylsulfonyl, amino- (C 1 -C 5) -haloalkylsulfonyl, (C 1 -C 5) -alkylaminosulfonyl , Bis [(Ci-Cr,) - alkyl] aminosulfonyl, (Ca-Ce cycloalkylaminosulfonyl, (Ci-C5) -haloalkylaminosulfonyl,
Heteroarylaminosulfonyl, Arylaminosulfonyl, Aryl-(CrC5)-alkylaminosulfonyl, (Ci-C5)-Alkylsulfonyl, (C3-C6)-Cycloalkylsulfonyl, Arylsulfonyl, Hydroxycarbonyl, (Ci-Cr>)-Alkoxycarbonyl, (Ca-CeJ-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl- (Ci-C5)-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C5)-alkoxycarbonyl, (C2-C5)- Alkenyloxycarbonyl, (C2-C5)-Alkinyloxycarbonyl, Aminocarbonyl, (C1-C5)- Alkylaminocarbonyl, Bis[(Ci-C5)-alkyl]aminocarbonyl, (Ci-C5)-Alkyl[(d-C5)- Alkyl]aminocarbonyl, (CrC5)-Alkyl[(Ci-C5)-Alkoxy]aminocarbonyl, (C2-C5)- Alkenylaminocarbonyl, (C3-C6)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(CrC5)-alkylaminocarbonyl stehen, A\ A2, A3 und A4 gleich oder verschieden sind und unabhängig voneinander für NHeteroarylaminosulfonyl, arylaminosulfonyl, aryl (CRC5) alkylaminosulfonyl, (Ci-C5) alkylsulfonyl, (C3-C6) cycloalkylsulfonyl, arylsulfonyl, hydroxycarbonyl, (Ci-Cr>) alkoxycarbonyl, (Ca-CeJ-cycloalkoxycarbonyl, (C3 -C 6) -cycloalkyl- (C 1 -C 5) -alkoxycarbonyl, aryloxycarbonyl, aryl- (C 1 -C 5) -alkoxycarbonyl, (C 2 -C 5) -alkenyloxycarbonyl, (C 2 -C 5) -alkynyloxycarbonyl, aminocarbonyl, (C 1 -C 5) - Alkylaminocarbonyl, bis [(Ci-C5) -alkyl] aminocarbonyl, (Ci-C5) -alkyl [(d-C5) - alkyl] aminocarbonyl, (CrC5) -alkyl [(Ci-C5) -alkoxy] aminocarbonyl, (C2 -C 5) - alkenylaminocarbonyl, (C 3 -C 6) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 5) -alkylaminocarbonyl, A \ A 2 , A 3 and A 4 are the same or different and are independently N
(Stickstoff) oder die Gruppierungen C-H, C-CH3, C-F, C-Cl, C-Br, Ol, OOCF3, C-OCH3, C-CF3, C-CO2H, C-CO2CH3 stehen, wobei jedoch in keinem Fall mehr als zwei N-Atome benachbart sind, (Nitrogen) or the groups CH, C-CH 3 , CF, C-Cl, C-Br, Ol, OOCF 3 , C-OCH 3 , C-CF 3 , C-CO 2 H, C-CO 2 CH 3 , but in no case more than two N atoms are adjacent,
R17 und R18 unabhängig voneinander für Wasserstoff, Fluor, Chlor, Brom, lod, (C1-C5)- Alkyl, gegebenenfalls substituiertes Phenyl, Heteroaryl, Heterocyclyl, (Cs-Ce)- Cycloalkyl, (C2-C5)-Alkenyl, (C2-C5)-Alkinyl, (Ci-C5)-Alkoxy, (0-C5)-Alkoxy- (Ci-O)-alkyl, Aryloxy-(Ci-C5)-alkyl, (Ci-C5)-Haloalkyl, (O-Oj)-Haloalkoxy- (Ci-Cr.)-alkyl, (Ci-C5)-Alkoxy-(Ci-C5)-haloalkyl, (Ci-C5)-Haloalkoxy-(Ci-C5)- haloalkyl, (Ci-C5)-Alkylthio-(Ci-C5)-alkyl, Hydroxycarbonyl, (C1-C5)- Alkoxycarbonyl, (O-OJ-Cycloalkoxycarbonyl, (O-O -CycloalkyKO-O)- alkoxycarbonyl, Aryloxycarbonyl, Aryl-(0-C5)-alkoxycarbonyl, (C2-C5)- Alkenyloxycarbonyl, (C2-C5)-Alkinyloxycarbonyl, Aminocarbonyl, (C1-C5)- Alkylaminocarbonyl, Bis[(Ci-C5)-alkyl]aminocarbonyl, (O-CsJ-Alkyl O-Cs)- Alkyljaminocarbonyl, (CrC5)-Alkyl[(Ci-Cr))-Alkoxy]aminocarbonyl, (C2-C5)- Alkenylaminocarbonyl, (C3-C6)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C5)-alkylaminocarbonyl stehen, R 17 and R 18 independently of one another represent hydrogen, fluorine, chlorine, bromine, iodine, (C 1 -C 5 ) -alkyl, optionally substituted phenyl, heteroaryl, heterocyclyl, (Cs-Ce) -cycloalkyl, (C 2 -C 5 ) - alkenyl, (C 2 -C 5) alkynyl, (Ci-C 5) alkoxy, (0-C 5) alkoxy (C-O) alkyl, aryloxy (Ci-C 5) alkyl, ( Ci-C 5 ) -haloalkyl, (O-Oj) -haloalkoxy- (Ci-Cr.) - alkyl, (Ci-C 5 ) -alkoxy- (Ci-C 5 ) -haloalkyl, (Ci-C 5 ) - Haloalkoxy- (C 1 -C 5 ) -haloalkyl, (C 1 -C 5 ) -alkylthio (C 1 -C 5 ) -alkyl, hydroxycarbonyl, (C 1 -C 5 ) -alkoxycarbonyl, (O-OJ-cycloalkoxycarbonyl, (OO -cycloalkyKO -O) - alkoxycarbonyl, aryloxycarbonyl, aryl- (O-C5) -alkoxycarbonyl, (C 2 -C 5) -alkenyloxycarbonyl, (C 2 -C 5) -alkynyloxycarbonyl, aminocarbonyl, (C 1 -C 5) -alkylaminocarbonyl, bis [(C 1 -C 5 ) -alkyl] aminocarbonyl, (O-CsJ-alkyl O-Cs) - alkyljaminocarbonyl, (CrC5) -alkyl [(Ci-Cr)) - alkoxy] aminocarbonyl, (C2-C5) -alkenylaminocarbonyl, (C3-C6) - Cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 5) -alkylaminocarbonyl,
A5 für S (Schwefel), O (Sauerstoff) oder die Gruppierungen N-H, N-CH3, N-CH2CH3, N- CH(CH3)2, N-C02t-Bu, N-Aryl, N-Heteroaryl, N-Heterocyclyl steht, A 5 represents S (sulfur), O (oxygen) or the groupings NH, N-CH 3 , N-CH 2 CH 3 , N-CH (CH 3 ) 2 , N-CO 2 t-Bu, N-aryl, N-heteroaryl, N-heterocyclyl is
R19, R20, R23 und R24 unabhängig voneinander für Wasserstoff, (Ci-Cs)-Alkyl, Fluor, Chlor, Brom, lod, (C3-C6)-Cycloalkyl, gegebenenfalls substituiertes Phenyl, Heteroaryl, Heterocyclyl, (C2-C5)-Alkenyl, Aryl-(Ci-C5)-alkyl, (Ci-C5)-Alkoxy, (Ci-C5)-Alkoxy-(Ci-C5)-alkoxy, (Ci-C5)-Alkoxy-(Ci-C5)-alkyl, Hydroxy, (C1-C5)- Haloalkyl, (Ci-CsJ-Haloalkylthio stehen, R 19 , R 20 , R 23 and R 24 independently of one another represent hydrogen, (C 1 -C 5) -alkyl, fluorine, chlorine, bromine, iodine, (C 3 -C 6) -cycloalkyl, optionally substituted phenyl, heteroaryl, heterocyclyl, (C 2 -C 5) alkenyl, aryl (Ci-C 5) alkyl, (Ci-C 5) alkoxy, (Ci-C 5) alkoxy (Ci-C 5) alkoxy, (Ci-C 5 ) alkoxy- (C 1 -C 5 ) -alkyl, hydroxy, (C 1 -C 5 ) -haloalkyl, (C 1 -C 5 -haloalkylthio),
R19 und R23 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden. R 19 and R 23 with the atoms to which they are attached form a fully saturated or partially saturated, optionally further substituted 5 to 7-membered ring.
A6, A7 gleich oder verschieden sind und unabhängig voneinander für O (Sauerstoff), S (Schwefel), N-H, N-OCH3, N-CH3 oder die Gruppierung CR21 R22 stehen, wobei jedoch in keinem Fall zwei N-, O- oder S-Atome benachbart sind, und wobei R21 und R22 in der Gruppierung CR21 R22 jeweils gleiche oder verschiedene A 6 , A 7 are identical or different and independently of one another represent O (oxygen), S (sulfur), NH, N-OCH 3, N-CH 3 or the group CR 21 R 22 , where however, in no case are two N, O or S atoms adjacent, and wherein R 21 and R 22 in the group CR 21 R 22 are each the same or different
Bedeutungen gemäß der nachstehenden Definition haben und  Have meanings as defined below and
R21 und R22 unabhängig voneinander für Wasserstoff, Fluor, Chlor, Brom, lod, (C1-C5)- Alkyl, gegebenenfalls substituiertes Phenyl, Heteroaryl, Heterocyclyl, (Ca-Ce)- Cycloalkyl, (C2-C5)-Alkenyl, (Ci-C5)-Alkoxy, (Ci-C5)-Alkoxy-(Ci-C5)-alkyl, (CrC5)-Haloalkoxy. (Ci-C5)-Haloalkyl, (CrC5)-Alkylthio, (Ci-C5)-Haloalkylthio, (Ci-C5)-Alkylthio-(Ci-C5)-alkyl, Hydroxycarbonyl, (Ci-Cr>)-Alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci-C5)-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(d-C5)-alkoxycarbonyl, (C2-C5)-Alkenyloxycarbonyl, (C2-C5)-Alkinyloxycarbonyl, Aminocarbonyl, (Ci-C5)-Alkylaminocarbonyl, Bis[(d-C5)-alkyl]aminocarbonyl, (Ci-C5)-Alkyl[(Ci-C5)-Alkyl]aminocarbonyl, (Ci-C5)-Alkyl[(CrC5)-Alkoxy]aminocarbonyl, (C2-C5)-Alkenylaminocarbonyl, (Ca-CeJ-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-Cs)- alkylaminocarbonyl, Amino, (Ci-Ca)-Alkylamino, (C3-C6)-Cycloalkylamino, Bis- [(d-Cr -Alkyljamino stehen, R 21 and R 22 independently of one another represent hydrogen, fluorine, chlorine, bromine, iodine, (C 1 -C 5 ) -alkyl, optionally substituted phenyl, heteroaryl, heterocyclyl, (Ca-Ce) -cycloalkyl, (C 2 -C 5 ) - Alkenyl, (C 1 -C 5 ) -alkoxy, (C 1 -C 5 ) -alkoxy- (C 1 -C 5 ) -alkyl, (C 1 -C 5 ) -haloalkoxy. (C 1 -C 5 ) -haloalkyl, (C 1 -C 5 ) -alkylthio, (C 1 -C 5 ) -haloalkylthio, (C 1 -C 5 ) -alkylthio (C 1 -C 5 ) -alkyl, hydroxycarbonyl, (C 1 -C 5 ) 2) Alkoxycarbonyl, (C3-C6) -cycloalkoxycarbonyl, (C3-C6) -cycloalkyl- (Ci-C5) -alkoxycarbonyl, aryloxycarbonyl, aryl- (d-C5) -alkoxycarbonyl, (C2-C5) -alkenyloxycarbonyl, (C2-C5 ) -Alkynyloxycarbonyl, aminocarbonyl, (C 1 -C 5) -alkylaminocarbonyl, bis [(C 1 -C 5) -alkyl] aminocarbonyl, (C 1 -C 5) -alkyl [(C 1 -C 5) -alkyl] aminocarbonyl, (C 1 -C 5) - Alkyl [(C 1 -C 5) -alkoxy] -aminocarbonyl, (C 2 -C 5) -alkenylaminocarbonyl, (C 1 -C 12 -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 8) -alkylaminocarbonyl, amino, (C 1 -C 4) -alkylamino, (C 3 -C 4) -alkyl) C 6) cycloalkylamino, bis [(d-C r -alkylamino,
R25, R26, R28 und R29 unabhängig voneinander für Wasserstoff, (Ci-Cs)-Alkyl, Fluor, Chlor, Brom, lod, (Ca-CeJ-Cycloalkyl, Aryl, Heteroaryl, Heterocyclyl, (C2-C5)- Alkenyl, Aryl-(CrC5)-alkyl, (CrC5)-Alkoxy, (Ci-C5)-Haloalkyl stehen, R 25 , R 26 , R 28 and R 29 independently of one another represent hydrogen, (C 1 -C 5) -alkyl, fluorine, chlorine, bromine, iodine, (C 1 -C 6 -cycloalkyl, aryl, heteroaryl, heterocyclyl, (C 2 -C 5) - alkenyl, aryl- (-C 5) alkyl, (CrC 5) alkoxy, (Ci-C 5) -haloalkyl stand,
A8 für O (Sauerstoff), S (Schwefel), N-H, N-CH3, N-OCH3 oder die Gruppierung CHR27 steht und wobei R27 in der Gruppierung CHR27 die Bedeutung gemäß der nachstehenden Definition hat, A 8 is O (oxygen), S (sulfur), NH, N-CH 3 , N -OCH 3 or the moiety CHR 27 , and wherein R 27 in the moiety CHR 27 has the meaning as defined below,
R27 für Wasserstoff, Fluor, Chlor, Brom, lod, (Ci-Cs)-Alkyl, gegebenenfalls R 27 represents hydrogen, fluorine, chlorine, bromine, iodine, (C 1 -C 8) -alkyl, if appropriate
substituiertes Phenyl, Heteroaryl, Heterocyclyl, (C:3-C6)-Cycloalkyl, (C2-C5)- Alkenyl, (Ci-C5)-Alkoxy, (Ci-C5)-Haloalkoxy, (Ci-C5)-Haloalkyl, (Ci-Cs)-Alkylthio, (CrCr>)-Haloalkylthio, Hydroxycarbonyl, (Ci-Cr>)-Alkoxycarbonyl, (Ca-Ce)- Cycloalkoxycarbonyl, Aryl-(d-C5)-alkoxycarbonyl, (C2-C5)-Alkenyloxycarbonyl, (C2-C5)-Alkinyloxycarbonyl, Aminocarbonyl, (d-C5)-Alkylaminocarbonyl, Bis[(Ci-C5)-alkyl]aminocarbonyl, (Ci-C5)-Alkyl[(Ci-C5)-Alkyl]aminocarbonyl, (Ci-C5)-Alkyl[(Ci-C5)-Alkoxy]aminocarbonyl, (C2-C5)-Alkenylaminocarbonyl, (C3-C6)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-Cs)- alkylaminocarbonyl, Amino, (Ci-Cr,)-Alkylamino, (Ca-CeJ-Cycloalkylamino, Bis- [(Ci-C5)-Alkyl]amino sieht, substituted phenyl, heteroaryl, heterocyclyl, (C: 3-C6) -cycloalkyl, (C 2 -C 5 ) -alkenyl, (C 1 -C 5 ) -alkoxy, (C 1 -C 5 ) -haloalkoxy, (C 1 -C 5 ) - haloalkyl, (Ci-Cs) -alkylthio, (CrCr>) haloalkylthio, hydroxycarbonyl, (Ci-Cr>) alkoxycarbonyl, (Ca-Ce) - cycloalkoxycarbonyl, aryl (d-C5) -alkoxycarbonyl, (C2-C5 ) Alkenyloxycarbonyl, (C 2 -C 5) -alkynyloxycarbonyl, aminocarbonyl, (C 1 -C 5) -alkylaminocarbonyl, bis [(C 1 -C 5) -alkyl] aminocarbonyl, (C 1 -C 5) -alkyl [(C 1 -C 5) -alkyl] aminocarbonyl, (C 1 -C 5) -alkyl [(C 1 -C 5) -alkoxy] -aminocarbonyl, (C 2 -C 5) -alkenylaminocarbonyl, (C3-C6) cycloalkylaminocarbonyl, arylaminocarbonyl, aryl (Ci-Cs) - alkylaminocarbonyl, amino, (Ci-Cr,) - alkylamino, (Ca-CeJ-cycloalkylamino, bis [(Ci-C 5) -alkyl] amino looks,
R30, R31, R32, R34, R35 und R36 unabhängig voneinander für Wasserstoff, (CrC5)-Alkyl, Halogen, (Ca-CeJ-Cycloalkyl, Aryl, Heteroaryl, Heterocyclyl, (C2-Cs)-Alkenyl, (CrC5)-Alkoxy, (CrC5)-Haloalkyl, (CrC5)-Alkylthio, (Ci-C5)-Haloalkylthio stehen. R 30 , R 31 , R 32 , R 34 , R 35 and R 36 independently of one another represent hydrogen, (C 1 -C 5 ) -alkyl, halogen, (C 1 -C 6 -cycloalkyl, aryl, heteroaryl, heterocyclyl, (C 2 -C 5 ) - alkenyl, (CrC 5) alkoxy, (CrC 5) haloalkyl, (CrC 5) alkylthio, (Ci-C 5) are haloalkylthio.
A9 für O (Sauerstoff), S (Schwefel), N-H, N-CH3, N-OCH3 oder die Gruppierung CHR3: steht und wobei R33 in der Gruppierung CHR33 die Bedeutung gemäß der nachstehenden Definition hat und A 9 is O (oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the moiety CHR 3: and wherein R 33 in the moiety CHR 33 has the meaning as defined below and
R33 für Wasserstoff, Fluor, Chlor, Brom, lod, (d-CsJ-Alkyl, gegebenenfalls R 33 is hydrogen, fluorine, chlorine, bromine, iodine, (d-CsJ-alkyl, optionally
substituiertes Phenyl, Heteroaryl, Heterocyclyl, (Cs-CeJ-Cycloalkyl, (C2-C5)- Alkenyl, (CrC5)-Alkoxy, (Ci-C5)-Alkoxy-(Ci-Cr>)-alkyl, (CrC5)-Haloalkoxy, substituted phenyl, heteroaryl, heterocyclyl, (Cs-CeJ-cycloalkyl, (C2-C5) - alkenyl, (CrC 5) alkoxy, (Ci-C 5) alkoxy (Ci-Cr>) alkyl, (CrC 5 ) -haloalkoxy,
(CrCr.)-Haloalkyl, (Ci-Cr.)-Alkylthio, (CrC5)-Haloalkylthio, Hydroxycarbonyl, (Ci-C5)-Alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, Aryl-(Ci-Cs)- alkoxycarbonyl, (C2-C5)-Alkenyloxycarbonyl, (C2-Cr>)-Alkinyloxycarbonyl, Aminocarbonyl, (Ci-C5)-Alkylaminocarbonyl, Bis[(Ci-C5)-alkyl]aminocarbonyl, (Ci-C5)-Alkyl[(Ci-C5)-Alkyl]aminocarbonyl, (Ci-C5)-Alkyl[(Ci-C5)- Alkoxyjaminocarbonyl, (C2-C5)-Alkenylaminocarbonyl, (Ca-Ce)- Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(CrCr»)-alkylaminocarbonyl, Amino, (Ci-Cr,)-Alkylamino, (Ca-CeJ-Cycloalkylamino, Bis-[(Ci-C5)-Alkyl]amino steht. (CrCr.) - Haloalkyl, (Ci-Cr.) - Alkylthio, (CrC 5 ) haloalkylthio, hydroxycarbonyl, (Ci-C5) alkoxycarbonyl, (C3-C6) -cycloalkoxycarbonyl, aryl- (Ci-Cs) - alkoxycarbonyl , (C2-C5) alkenyloxycarbonyl, (C2-Cr>) -alkynyloxycarbonyl, aminocarbonyl, (Ci-C5) alkylaminocarbonyl, bis [(Ci-C5) alkyl] aminocarbonyl, (Ci-C 5) alkyl [( Ci-C 5 ) -alkyl] aminocarbonyl, (Ci-C 5 ) -alkyl [(Ci-C 5 ) - Alkoxyjaminocarbonyl, (C2-C5) -alkenylaminocarbonyl, (Ca-Ce) - Cycloalkylaminocarbonyl, arylaminocarbonyl, aryl (CrCr ») -Alkylaminocarbonyl, amino, (Ci-Cr,) - alkylamino, (Ca-CeJ-cycloalkylamino, bis - [(Ci-C5) -alkyl] amino.
Ganz besonders bevorzugt sind Verbindungen der allgemeinen Formel (I), die durch die Formeln (la) bis (lo) beschrieben werden, Very particular preference is given to compounds of the general formula (I) which are described by the formulas (Ia) to (Io)
worin  wherein
[X-Y] für die Gruppierung [XY] for the grouping
steht, wobei R13, R14, R15, R16, R17, R18, R19, R20, R23, R24, R25, R26, R28, R29, R30, R31, R32, R34, R35 und R36 sowie A1 bis A9 jeweils die Bedeutung gemäß der nachstehenden Definitionen haben und wobei der Pfeil für eine Bindung zur jeweiligen Gruppierung C-R6 in den vorgenannten Formeln (la) bis (lo) steht, für Hydroxy, Methoxy, Ethoxy, n-Propyloxy, Methylcarbonyloxy, where R 13 , R 14 , R 15 , R 16 , R 17 , R 18 , R 19 , R 20 , R 23 , R 24 , R 25 , R 26 , R 28 , R 29 , R 30 , R 31 , R 32 , R 34 , R 35 and R 36 and A 1 to A 9 each have the meaning as defined below and wherein the arrow for a bond to the respective group CR 6 in the aforementioned formulas (la) to (lo) , for hydroxy, methoxy, ethoxy, n-propyloxy, methylcarbonyloxy,
Ethylcarbonyloxy, n-Propylcarbonyloxy, i-Propylcarbonyloxy, n- Butylcarbonyloxy, sec-Butylcarbonyloxy, tert.-Butylcarbonyloxy, n- Pentylcarbonyloxy, Phenylcarbonyloxy, p-CI-Phenylcarbonyloxy, p- Methylphenylcarbonyloxy, p-Trifluormethylphenylcarbonyloxy, p- Methoxyphenylcarbonyloxy, o-CI-Phenylcarbonyloxy, o- Methylphenylcarbonyloxy, o-Trifluormethylphenylcarbonyloxy, o- Methoxyphenylcarbonyloxy, 2-Pyridylcarbonyloxy, 3-Pyridylcarbonyloxy, 4- Pyridylcarbonyloxy, 6-Trifluormethyl-3-Pyridylcarbonyloxy, 4-Chlor-3- Pyridylcarbonyloxy, Cyclopropylcarbonyloxy, Cyclobutylcarbonyloxy, Ethylcarbonyloxy, n-propylcarbonyloxy, i -propylcarbonyloxy, n-butylcarbonyloxy, sec-butylcarbonyloxy, tert -butylcarbonyloxy, n-pentylcarbonyloxy, phenylcarbonyloxy, p-CI-phenylcarbonyloxy, p-methylphenylcarbonyloxy, p-trifluoromethylphenylcarbonyloxy, p-methoxyphenylcarbonyloxy, o-CI Phenylcarbonyloxy, o-methylphenylcarbonyloxy, o-trifluoromethylphenylcarbonyloxy, o-methoxyphenylcarbonyloxy, 2-pyridylcarbonyloxy, 3-pyridylcarbonyloxy, 4-pyridylcarbonyloxy, 6-trifluoromethyl-3-pyridylcarbonyloxy, 4-chloro-3-pyridylcarbonyloxy, cyclopropylcarbonyloxy, cyclobutylcarbonyloxy,
Cyclopentylcarbonyloxy, Cyclohexylcarbonyloxy, Methoxycarbonyloxy, Cyclopentylcarbonyloxy, cyclohexylcarbonyloxy, methoxycarbonyloxy,
Ethoxycarbonyloxy, Trimethylsilyloxy, Triethylsilyloxy, Triisopropylsilyloxy Dirne thylphenylsilyloxy, tert.-Butyldimethylsilyloxy steht, für ethylsulfonylaminocarbonyl, Ethylsulfonylaminocarbonyl, n- Propylsulfonylaminocarbonyl, iso-Propylsulfonylaminocarbonyl, Ethoxycarbonyloxy, trimethylsilyloxy, triethylsilyloxy, triisopropylsilyloxy, thylphenylsilyloxy, tert-butyldimethylsilyloxy, ethylsulfonylaminocarbonyl, ethylsulfonylaminocarbonyl, n-propylsulfonylaminocarbonyl, iso-propylsulfonylaminocarbonyl,
Cyclopropylsulfonylaminocarbonyl, Cyclobutylsulfonylaminocarbonyl, Cyclopropylsulfonylaminocarbonyl, cyclobutylsulfonylaminocarbonyl,
Cyclopentylsulfonylaminocarbonyl, Cyclohexylsulfonylaminocarbonyl, Cyclopentylsulfonylaminocarbonyl, cyclohexylsulfonylaminocarbonyl,
Hydroxycarbonyl, Methoxycarbonyl, Ethoxycarbonyl, n-Propyloxycarbonyl, iso- Propyloxycarbonyl, n-Butyloxycarbonyl, sec-Butyloxycarbonyl, tert.- Butyloxycarbonyl, n-Pentyloxycarbonyl, neo-Pentyloxycarbonyl, n- Hexyloxycarbonyl, Benzyloxycarbonyl, p-Chlorbenzyloxycarbonyl, p- Methoxybenzyloxycarbonyl, p-Fluorbenzyloxycarbonyl, p- Methylbenzyloxycarbonyl, Methoxyethoxycarbonyl, Ethoxyethoxycarbonyl, Ethoxymethoxycarbonyl, ethoxy-n-propyloxycarbonyl, Ethoxy-n- propoxycarbonyl, Cyclopropyloxycarbonyl, Cyclobutyloxycarbonyl, Hydroxycarbonyl, methoxycarbonyl, ethoxycarbonyl, n-propyloxycarbonyl, iso -propyloxycarbonyl, n-butyloxycarbonyl, sec-butyloxycarbonyl, tert-butyloxycarbonyl, n-pentyloxycarbonyl, neo-pentyloxycarbonyl, n-hexyloxycarbonyl, benzyloxycarbonyl, p-chlorobenzyloxycarbonyl, p-methoxybenzyloxycarbonyl, p Fluorobenzyloxycarbonyl, p-methylbenzyloxycarbonyl, methoxyethoxycarbonyl, ethoxyethoxycarbonyl, ethoxymethoxycarbonyl, ethoxy-n-propyloxycarbonyl, ethoxy-n-propoxycarbonyl, cyclopropyloxycarbonyl, cyclobutyloxycarbonyl,
Cyclopentyloxycarbonyl, Cyclohexyloxycarbonyl, (C2-C6)-alkinyloxycarbonyl, 2.2,-Difluorethoxycarbonyl, 2,2,2-Trifluorethoxycarbonyl, Methylaminocarbonyl, Ethylaminocarbonyl, n-Propylaminocarbonyl, iso-Propylaminocarbonyl, n- Butylaminocarbonyl, iso-Butylaminocarbonyl, tert.-Butylaminocarbonyl, n- Pentylaminocarbonyl, neo-Pentylaminocarbonyl, iso-Pentylaminocarbonyl, Cyclopropylaminocarbonyl, Cyclobutylaminocarbonyl, Cyclopentyloxycarbonyl, cyclohexyloxycarbonyl, (C 2 -C 6) -alkynyloxycarbonyl, 2,2-difluoroethoxycarbonyl, 2,2,2-trifluoroethoxycarbonyl, methylaminocarbonyl, ethylaminocarbonyl, n-propylaminocarbonyl, isopropylaminocarbonyl, n-butylaminocarbonyl, isobutylaminocarbonyl, tert-butylaminocarbonyl, n-pentylaminocarbonyl, neo-pentylaminocarbonyl, iso-pentylaminocarbonyl, cyclopropylaminocarbonyl, cyclobutylaminocarbonyl,
Cyclopentylaminocarbonyl, Cyclohexylaminocarbonyl, Piperidinyl-N-carbonyl, Pyrrolidinyl-N-carbonyl, Cyanomethylaminocarbonyi, Cyanoethylaminocarbonyl, Cyano-n-propylaminocarbonyl, Cyano-n-butylaminocarbonyl, Cyclopentylaminocarbonyl, cyclohexylaminocarbonyl, piperidinyl-N-carbonyl, pyrrolidinyl-N-carbonyl, cyanomethylaminocarbonyl, cyanoethylaminocarbonyl, cyano-n-propylaminocarbonyl, cyano-n-butylaminocarbonyl,
Dimethylaminocarbonyl, Diethylaminocarbonyl, Diisopropylaminocarbonyl, Methoxyethylaminocarbonyl, Ethoxyethylaminocarbonyl, Formyl, Dimethylaminocarbonyl, diethylaminocarbonyl, diisopropylaminocarbonyl, methoxyethylaminocarbonyl, ethoxyethylaminocarbonyl, formyl,
Hydroxyiminomethyl, Methoxyiminomethyl, Ethoxyiminomethyl, n- Propyloxyiminomethyl, iso-Propyloxyiminomethyl, n-Butyloxyiminomethyl, iso- Butyloxyiminomethyl, tert.-Butyloxyiminomethyl, Hydroxyiminomethyl, methoxyiminomethyl, ethoxyiminomethyl, n-propyloxyiminomethyl, iso-propyloxyiminomethyl, n-butyloxyiminomethyl, iso-butyloxyiminomethyl, tert-butyloxyiminomethyl,
Cyclopropylmethoxyiminomethyl, (C1-C5)- Alkylsulfonylaminocarbonyl, (C3-C5)- Cycloalkylsulfonylaminocarbonyl, (C3-C6)-Cycloalkyl-(Ci-C5)-alkoxycarbonyl, Aryloxycarbonyl, (C2-C5)-Alkenyloxycarbonyl, (C2-C5)-Alkinyloxycarbonyl, (d-C5)-Haloalkyloxycarbonyl, (C2-C5)-Alkenyloxy-(Ci-C5)-alkoxycarbonyl, (Ci-C5)-Alkylamino-(Ci-C5)-alkoxycarbonyl, Tris[(Ci-C5)-alkyl]silyloxy-(Ci-Cr>)- alkoxycarbonyl, Bis[(Ci-C5)-Alkyl]amino-(CrC5)-alkoxycarbonyl, (C1-C5)- Alkyl[(Ci-C5)-alkyl]amino-(Ci-C5)-alkoxycarbonyl, Cyano-(Ci-Cs)- alkoxycarbonyl, Heierocyclyl-N-(Ci-C5)-alkoxycarbonyl, Heteroaryloxycarbonyl, Heteroaryl-(CrC5)-alkoxycarbonyl, Heterocyclyl-(CrC5)-alkoxycarbonyl, Heterocyclyloxycarbonyl, (C2-C5)-Alkenyl-(d-C5)-alkoxycarbonyl, (C2-C5)- Alkinyl-(d-C5)-alkoxycarbonyl, Aryl-(C2-C5)-alkinyloxycarbonyl, Aryi-(C2-Cs)- alkenyloxycarbonyl, Aminocarbonyl, (Ci-C5)-Alkyl[(Ci-C5)-Alkyl]aminocarbonyl, (Ci-C5)-Alkyl[(CrC5)-Alkoxy]aminocarbonyl, (C2-C5)-Alkenylaminocarbonyl, (C3-C6)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(CrC5)- alkylaminocarbonyl, Heteroaryl-(Ci-Cr,)-alkylaminocarbonyl, (C1-C5)- Haloalkylaminocarbonyl, (C2-C5)-Alkinyl-(Ci-C5)-alkylaminocarbonyl, (C1-C5)- Alkoxycarbonylaminocarbonyl, Aryl-(Ci-C5)-alkoxycarbonylaminocarbonyl, Hydroxycarbonyl-(Ci-C5)-alkyl, (Ci-C5)-Alkoxycarbonyl-(Ci-C5)-alkyl, (C3-C6)- Cycloalkoxycarbonyl-(CrC5)-alkyl, (C:rC6)-Cycloalkyl-(Ci-C5)-alkoxycarbonyl- (Ci-C5)-alkyl, (C2-C5)-Alkenyloxycarbonyl-(Ci-C5)-alkyl, Aryl-(Ci-C5)- alkoxycarbonyl-(d-C5)-alkyl, Aminosulfonyl, (Ci-C8)-Alkoxycarbonyl- heterocyclyl-N-carbonyl, (Ci-C8)-Alkoxycarbonyl-(d-C8)-alkyl- heterocyclylidenaminocarbonyl, (Ci-C8)-Alkoxycarbonylheterocyclyliden-(CrC8)- alkylaminocarbonyl (Ci-C8)-Alkoxycarbonyl-(CrC8)-Alkyl((Ci-C8)- alkyl)aminocarbonyl, (Ci-C8)-Alkoxycarbonyl-(C3-C8)- cycloalkylidenaminocarbonyl, (Ci-C5)-Alkylaminocarbonyl-(Ci-C5)-alkyl, Cyclopropylmethoxyiminomethyl, (C 1 -C 5) -alkylsulfonylaminocarbonyl, (C 3 -C 5) -cycloalkylsulfonylaminocarbonyl, (C 3 -C 6) -cycloalkyl- (C 1 -C 5) -alkoxycarbonyl, aryloxycarbonyl, (C 2 -C 5) -alkenyloxycarbonyl, (C 2 -C 5) - Alkynyloxycarbonyl, (C 1 -C 5 ) -haloalkyloxycarbonyl, (C 2 -C 5 ) -alkenyloxy- (C 1 -C 5 ) -alkoxycarbonyl, (C 1 -C 5 ) -alkylamino- (C 1 -C 5 ) -alkoxycarbonyl, tris [(Ci-C 5 ) -alkyl] silyloxy- (C 1 -C 8) - alkoxycarbonyl, bis [(C 1 -C 5) -alkyl] amino- (C 1 -C 5) -alkoxycarbonyl, (C 1 -C 5) -alkyl [(C 1 -C 5) -alkyl] amino (Ci-C5) alkoxycarbonyl, cyano (Ci-Cs) - alkoxycarbonyl, heierocyclyl-N- (C 1 -C 5) -alkoxycarbonyl, heteroaryloxycarbonyl, heteroaryl- (C 1 -C 5) -alkoxycarbonyl, heterocyclyl- (C 1 -C 5) -alkoxycarbonyl, heterocyclyloxycarbonyl, (C 2 -C 5) -alkenyl- (C 1 -C 5) -alkoxycarbonyl, (C 2 -C 5) - alkynyl- (C 1 -C 5) -alkoxycarbonyl, aryl- (C 2 -C 5) -alkynyloxycarbonyl, aryl- (C 2 -C 5) -alkenyloxycarbonyl, aminocarbonyl, (C 1 -C 5) -alkyl [(C 1 -C 5) ) -Alkyl] aminocarbonyl, (C 1 -C 5) -alkyl [(C 1 -C 5) -alkoxy] -aminocarbonyl, (C 2 -C 5) -alkenylaminocarbonyl, (C 3 -C 6) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 5) -alkylaminocarbonyl, heteroaryl- (C 1 -C 18) -alkylaminocarbonyl, (C 1 -C 5) -haloalkylaminocarbonyl, (C 2 -C 5) -alkynyl- (C 1 -C 5) -alkylaminocarbonyl, (C 1 -C 5) -alkoxycarbonylaminocarbonyl, aryl- (C 1 -C 5) -alkoxycarbonylaminocarbonyl , hydroxycarbonyl- (Ci-C 5) alkyl, (Ci-C 5) alkoxycarbonyl (Ci-C 5) alkyl, (C 3 -C 6) - cycloalkoxycarbonyl (CRC5) alkyl, (C: RC6 ) -Cycloalkyl- (C 1 -C 5 ) -alkoxycarbonyl- (C 1 -C 5 ) -alkyl, (C 2 -C 5 ) -alkenyloxycarbonyl- (C 1 -C 5 ) -alkyl, aryl- (C 1 -C 5 ) -alkoxycarbonyl- (d-C5) -al kyl, aminosulfonyl, (C 1 -C 8) -alkoxycarbonyl-heterocyclyl-N-carbonyl, (C 1 -C 8) -alkoxycarbonyl- (C 1 -C 8) -alkyl-heterocyclylideneaminocarbonyl, (C 1 -C 8) -alkoxycarbonylheterocyclylidene- (C 1 -C 8) -alkylaminocarbonyl ( C 1 -C 8) -alkoxycarbonyl- (C 1 -C 8) -alkyl ((C 1 -C 8) -alkyl) aminocarbonyl, (C 1 -C 8) -alkoxycarbonyl- (C 3 -C 8) -cycloalkylideneaminocarbonyl, (C 1 -C 5) -alkylaminocarbonyl- (C 1 -C 4) -cyclo C5) alkyl,
Aminocarbonyl-(Ci-C5)-alkyl, Bis[(Ci-C5)-alkyl]aminocarbonyl-(Ci-Cr>)-alkyl, (C3-Cr>)-Cycloalkylaminocarbonyl-(Ci-C5)-alkyl, Aryl-(CrC5)-alkylaminocarbonyl- (Ci-C5)-alkyl, Heteroaryl-(Ci-C5)-alkylaminocarbonyl-(Ci-C5)-alkyl, Cyano- (Ci-C5)-alkylaminocarbonyl-(Ci-C5)-alkyl, (Ci-Cr>)-Haloalkylaminocarbonyl- (CrC5)-alkyl, (C2-C5)-Alkinyi-(Ci-C5)-alkylaminocarbonyl-(Ci-C5)-alkyl, (C3-C6)- Cycloalkyl-(Ci-C5)-alkylaminocarbonyl-(Ci-C5)-alkyl, (C1-C5)- Alkoxycarbonylaminocarbonyl-(CrC5)-alkyl, Aryl-(Ci-Cr>)- alkoxycarbonylaminocarbonyl-(Ci-C5)-alkyl, (Ci-C5)-Alkoxycarbonyl-(Ci-C5)- alkylaminocarbonyl, Hydroxycarbonyl-(Ci-C5)-alkylaminocarbonyl, Aryl-(Ci-C5)- alkoxycarbonyl-(Ci-C5)-alkylaminocarbonyl, Aminocarbonyl-(Ci-C5)- alkylaminocarbonyl, (Ci-C5)-Alkylaminocarbonyl-(Ci-Cr>)-alkylaminocarbonyl, (C3-C6)-Cycloalkylaminocarbony!-(Ci-C5)-alkylaminocarbonyL (Cs-Ce)- Cycloalkyl-(Ci-C5)-alkylaminocarbonyl, (C3-C6)-Cycloalkyl-(Ci-C5)- alkylaminocarbonyi-(Ci-C5)-alkyl, (C3-C6)-Cycloalkyl-(Ci-C5)- alkylaminocarbonyl-(Ci-C5)-alkylaminocarbonyl, (C2-C5)-Alkenyl-(Ci-C5)- alkylaminocarbonyl, (C2-C5)-Alkenylaminocarbonyl-(Ci-C5)-alkyl, (C2-C5)- Alkenyl-(Ci-C5)-alkylaminocarbonyl-(Ci-Cr.)-alkyl, (CrC5)-Alkylcarbonyl, (C3-C6)- Cycloalkylcarbonyl, Arylcarbonyl, Formyl, Aminoiminomethyl, (C1-C5)- Alkylaminoiminomethyl, Bis[(Ci-C5)-alkyl]aminoiminomethyl, (C3-C6)- Cycloalkoxyiminomethyl, Aryloximinomethyl, Aryl-(C i-C5)-alkoxyiminomethyl,Aminocarbonyl (Ci-C5) alkyl, bis [(Ci-C5) alkyl] aminocarbonyl (C Cr>) alkyl, (C3-Cr>) -Cycloalkylaminocarbonyl- (Ci-C5) alkyl, aryl (C 1 -C 5) -alkylaminocarbonyl- (C 1 -C 5) -alkyl, heteroaryl- (C 1 -C 5) -alkylaminocarbonyl- (C 1 -C 5) -alkyl, cyano- (C 1 -C 5) -alkylaminocarbonyl- (C 1 -C 5) -alkyl, (Ci-Cr>) -Haloalkylaminocarbonyl- (-C 5) alkyl, (C2-C5) -Alkinyi- (Ci-C 5) alkylaminocarbonyl (Ci-C5) alkyl, (C 3 -C 6) - cycloalkyl (Ci-C5) alkylaminocarbonyl (Ci-C 5) alkyl, (C1-C5) - alkoxycarbonylaminocarbonyl- (CRC5) alkyl, aryl (Ci-Cr>) - alkoxycarbonylaminocarbonyl- (Ci-C5) alkyl, (C 1 -C 5) -alkoxycarbonyl- (C 1 -C 5) -alkylaminocarbonyl, hydroxycarbonyl- (C 1 -C 5) -alkylaminocarbonyl, aryl- (C 1 -C 5) -alkoxycarbonyl- (C 1 -C 5) -alkylaminocarbonyl, aminocarbonyl- Ci-C5) - alkylaminocarbonyl, (C-C5) alkylaminocarbonyl (Ci-Cr>) alkylaminocarbonyl, (C3-C6) -Cycloalkylaminocarbony - (Ci-C5) alkylaminocarbonyl (Cs-Ce) - cycloalkyl- (Ci -C 5) alkylaminocarbonyl, (C3-C6) cycloalkyl (Ci-C 5) - alkylaminocarbonyi- (Ci-C5) -alky l, (C 3 -C 6 ) -cycloalkyl- (C 1 -C 5 ) -alkylaminocarbonyl- (C 1 -C 5 ) -alkylaminocarbonyl, (C 2 -C 5 ) -alkenyl- (C 1 -C 5 ) - alkylaminocarbonyl, (C 2 -C 5 ) -alkenylaminocarbonyl- (C 1 -C 5 ) -alkyl, (C 2 -C 5 ) -alkenyl- (C 1 -C 5 ) -alkylaminocarbonyl- (C 1 -C 6) -alkyl, (C 1 -C 5 ) -alkylcarbonyl , (C 3 -C 6 ) -cycloalkylcarbonyl, arylcarbonyl, formyl, aminoiminomethyl, (C 1 -C 5 ) -alkylaminoiminomethyl, bis [(C 1 -C 5 ) -alkyl] aminoiminomethyl, (C 3 -C 6 ) -cycloalkoxyiminomethyl, aryloximinomethyl, aryl- C i -C 5) alkoxyiminomethyl,
Aryl-(Ci-C5)-alkylaminoiminomethyL (C2-C5)-Alkenyloxyiminomethyl, Aryl- (C 1 -C 5) -alkylaminoiminomethyl (C 2 -C 5) -alkenyloxyiminomethyl,
Arylaminoiminomethyl, Arylsulfonylaminoiminomethyl, Hydroxyaminocarbonyl, (Ci-C5)-Alkoxyaminocarbonyl, Aryl-(Ci-C6)-alkoxyaminocarbonyl steht, R13, R14, R15 und R16 unabhängig voneinander für Wasserstoff, Fluor, Chlor, Brom, lod, Nitro, Amino, Cyano, Methyl, Ethyl, n-Propyl, iso-Propyl, n-Butyl, sec-Butyl, iso- Butyl, tert. Butyl, Cyclopropyl, Cyclobutyl, Cyclopentyl, Cyclohexyl, Arylaminoiminomethyl, arylsulfonylaminoiminomethyl, hydroxyaminocarbonyl, (C 1 -C 5) -alkoxyaminocarbonyl, aryl- (C 1 -C 6) -alkoxyaminocarbonyl, R 13 , R 14 , R 15 and R 16 are each independently hydrogen, fluoro, chloro, bromo, iodo, nitro , Amino, cyano, methyl, ethyl, n-propyl, iso-propyl, n-butyl, sec-butyl, iso-butyl, tert. Butyl, cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl,
gegebenenfalls substituiertes Phenyl, Heteroaryl, Hydroxy, Methoxy, Ethoxy, n- Propyloxy, iso-Propyloxy, n-Butyloxy, sec-Butyloxy, iso-Butyloxy, tert.-Butyloxy, Methoxyethoxy, Methoxymethoxy, Ethoxyethoxy, Ethoxymethoxy, Methoxy-n- propyloxy, Methoxymethyl, Ethoxymethyl, Methoxyethyl, Ethoxyethyl,  optionally substituted phenyl, heteroaryl, hydroxy, methoxy, ethoxy, n-propyloxy, iso-propyloxy, n-butyloxy, sec-butyloxy, iso-butyloxy, tert-butyloxy, methoxyethoxy, methoxymethoxy, ethoxyethoxy, ethoxymethoxy, methoxy-n-propyloxy , Methoxymethyl, ethoxymethyl, methoxyethyl, ethoxyethyl,
Hydroxymethyl, Trifluormethoxy, Difluormethoxy, 2,2-Difluorethoxy, 3,3,3- Trifluorethoxy, Trifluormethyl, Difluormethyl, 2.2-Difluorethyl, 3.3,3-Trifluorethyl, Pentafluorethyl, Hydrothio, Methylthio, Trifluormethylthio, Methylamino,  Hydroxymethyl, trifluoromethoxy, difluoromethoxy, 2,2-difluoroethoxy, 3,3,3-trifluoroethoxy, trifluoromethyl, difluoromethyl, 2,2-difluoroethyl, 3,3,3-trifluoroethyl, pentafluoroethyl, hydrothio, methylthio, trifluoromethylthio, methylamino,
Ethylamino, Dimethylamino, Diethylamino, Allylamino, Cyclopropylamino, Ethylamino, dimethylamino, diethylamino, allylamino, cyclopropylamino,
Cyclobutylamino, Cyclopentylamino, Cyclohexylamino, Methylcarbonylamino, Ethylcarbonylamino, n-Propylcarbonylamino, iso-Propylcarbonylamino, n- Butylcarbonylamino, iso-Butylcarbonylamino, tert.-Butylcarbonylamino, Cyclobutylamino, cyclopentylamino, cyclohexylamino, methylcarbonylamino, ethylcarbonylamino, n-propylcarbonylamino, iso-propylcarbonylamino, n-butylcarbonylamino, iso-butylcarbonylamino, tert-butylcarbonylamino,
Cyclopropylcarbonylamino, Cyclobutylcarbonylamino,  Cyclopropylcarbonylamino, cyclobutylcarbonylamino,
Cyclopentylcarbonylamino, Cyclohexylcarbonylamino, Arylcarbonylamino, Cyclopentylcarbonylamino, cyclohexylcarbonylamino, arylcarbonylamino,
Heteroarylcarbonylamino, Trifiuormethylcarbonylamino, Methoxycarbonyiamino, Ethoxycarbonylamino, Methylsulfonylamino, Ethylsulfonylamino, n- Propylsulfonylamino, Cyclopropylsulfonylamino, Cyclobutylsulfonylamino, Cyclopentylsulfonylamino, Cyclohexylsulfonylamino, Arylsulfonylamino, Heteroarylcarbonylamino, trifluoromethylcarbonylamino, methoxycarbonyiamino, ethoxycarbonylamino, methylsulfonylamino, ethylsulfonylamino, n-propylsulfonylamino, cyclopropylsulfonylamino, cyclobutylsulfonylamino, cyclopentylsulfonylamino, cyclohexylsulfonylamino, arylsulfonylamino,
Hetarylsulfonylamino, Hydroxy carbonyl, Methoxycarbonyl, Ethoxycarbonyl, n- Hetarylsulfonylamino, hydroxy carbonyl, methoxycarbonyl, ethoxycarbonyl, n-
Propyloxycarbonyl, iso-Propyloxycarbonyl, n-Butyloxycarbonyl, iso- Butyloxycarbonyl, tert.-Butyloxycarbonyl, Cyclopropyloxycarbonyl, Propyloxycarbonyl, iso-propyloxycarbonyl, n-butyloxycarbonyl, iso-butyloxycarbonyl, tert-butyloxycarbonyl, cyclopropyloxycarbonyl,
Cyclobutyloxycarbonyl, Cyclopentyloxycarbonyl, Cyclohexyloxycarbonyl, Cyclopropylmethoxycarbonyl, Cyclohexylmethoxycarbonyl, Aryloxycarbonyl, Benzyloxycarbonyl, p-Chlorbenzyloxycarbonyl, p- ethoxybenzyloxycarbonyl, Allyloxycarbonyl, (C2-C5)-Alkinyloxycarbonyl, Aminocarbonyl, (C1-C5)- Alkylaminocarbonyl, Bis[(Ci-C5)-alkyl]aminocarbonyl, (Ci-C5)-Alkyl[(d-C5)- Alkyljaminocarbonyl, (Ci-C5)-Alkyl-[(CrC5)-Alkoxy]aminocarbonyl, (C2-C5)- Alkenylaminocarbonyl, (C3-C6)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C5)-alkylaminocarbonyl stehen, Cyclobutyloxycarbonyl, cyclopentyloxycarbonyl, cyclohexyloxycarbonyl, cyclopropylmethoxycarbonyl, cyclohexylmethoxycarbonyl, aryloxycarbonyl, Benzyloxycarbonyl, p-chlorobenzyloxycarbonyl, p-ethoxybenzyloxycarbonyl, allyloxycarbonyl, (C 2 -C 5) -alkynyloxycarbonyl, aminocarbonyl, (C 1 -C 5) -alkylaminocarbonyl, bis [(C 1 -C 5) -alkyl] aminocarbonyl, (C 1 -C 5) -alkyl [ (d-C5) - alkylaminocarbonyl, (C 1 -C 5) -alkyl- [(C 1 -C 5) -alkoxy] -aminocarbonyl, (C 2 -C 5) -alkenylaminocarbonyl, (C 3 -C 6) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 5) alkylaminocarbonyl,
A1 , A2, A3 und A4 gleich oder verschieden sind und unabhängig voneinander für N A 1 , A 2 , A 3 and A 4 are the same or different and are independently N
(Stickstoff) oder die Gruppierungen C-H, C-CH3, C-F, C-Cl, C-Br, C-l, C-OCF3, C-OCH3, C-CF3, C-CO2H, C-CO2CH3 stehen, wobei jedoch in keinem Fall mehr als zwei N-Atome benachbart sind, (Nitrogen) or the groupings CH, C-CH3, CF, C-Cl, are C-Br Cl, C-OCF3, C-OCH3, C-CF 3, C-CO2H, C-CO2CH3, but in no Case more than two N atoms are adjacent,
R17 und R18 unabhängig voneinander für Wasserstoff, Fluor, Chlor, Brom, lod, Methyl, Ethyl, iso-Propyl, gegebenenfalls substituiertes Phenyl, Heteroaryl, R 17 and R 18 independently of one another represent hydrogen, fluorine, chlorine, bromine, iodine, methyl, ethyl, isopropyl, optionally substituted phenyl, heteroaryl,
Heterocyclyl, Cyclopropyl, Cyclobutyl, Cyclopentyl, Cyclohexyl, Trifluormethyl, Difluormethyl, Hydroxycarbonyl, Methoxycarbonyl, Ethoxycarbonyl, tert.- Butyloxycarbonyl, Benzyloxycarbonyl, Allyloxycarbonyl, Aminocarbonyl, Methylaminocarbonyl, Ethylaminocarbonyl , iso-Propylaminocarbonyl,  Heterocyclyl, cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, trifluoromethyl, difluoromethyl, hydroxycarbonyl, methoxycarbonyl, ethoxycarbonyl, tert-butyloxycarbonyl, benzyloxycarbonyl, allyloxycarbonyl, aminocarbonyl, methylaminocarbonyl, ethylaminocarbonyl, isopropylaminocarbonyl,
Dimethylaminocarbonyl, Allylaminocarbonyl, Cyclopropylaminocarbonyl, Cyclobutylaminocarbonyl, Cyclopentylaminocarbonyl,  Dimethylaminocarbonyl, allylaminocarbonyl, cyclopropylaminocarbonyl, cyclobutylaminocarbonyl, cyclopentylaminocarbonyl,
Cyclohexylaminocarbonyl, Benzylaminocarbonyl stehen,  Cyclohexylaminocarbonyl, benzylaminocarbonyl,
A5 für S (Schwefel), O (Sauerstoff) oder die Gruppierungen N-H, N-CH3, N-CH2CH3, N- CH(CH3)2, N-C02t-Bu, N-Aryl, N-Heteroaryl, N-Heterocyclyl steht, A 5 for S (sulfur), O (oxygen) or the groupings NH, N-CH 3 , N-CH 2 CH 3 , N-CH (CH 3 ) 2 , N-CO 2 t-Bu, N-aryl, N-heteroaryl , N-heterocyclyl,
R19, R20, R23 und R24 unabhängig voneinander für Wasserstoff, Methyl, Ethyl, iso- Propyl, Fluor, Chlor, Brom, lod, Cyclopropyl, Cyclobutyl, Cyclopentyl, R 19 , R 20 , R 23 and R 24 are each independently hydrogen, methyl, ethyl, iso-propyl, fluorine, chlorine, bromine, iodine, cyclopropyl, cyclobutyl, cyclopentyl,
Cyclohexyl, gegebenenfalls substituiertes Phenyl, Heteroaryl, Heterocyclyl, Trifluormethyl, Difluormethyl stehen,  Cyclohexyl, optionally substituted phenyl, heteroaryl, heterocyclyl, trifluoromethyl, difluoromethyl,
R19 und R23 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden. A6, A7 gleich oder verschieden sind und unabhängig voneinander für O (Sauerstoff), S (Schwefel), N-H, N-OCH3, N-CH3 oder die Gruppierung CR21R22 stehen, wobei jedoch in keinem Fall zwei N-, O- oder S-Atome benachbart sind, und wobei R21 und R22 in der Gruppierung CR21R22 jeweils gleiche oder verschiedene R 19 and R 23 with the atoms to which they are attached form a fully saturated or partially saturated, optionally further substituted 5 to 7-membered ring. A 6 , A 7 are identical or different and independently of one another are O (oxygen), S (sulfur), NH, N-OCH 3 , N-CH 3 or the group CR 21 R 22 , but in no case are two N , O or S atoms are adjacent, and wherein R 21 and R 22 in the group CR 21 R 22 are each the same or different
Bedeutungen gemäß der nachstehenden Definition haben und  Have meanings as defined below and
R21 und R22 unabhängig voneinander für Wasserstoff, Fluor, Chlor, Brom, lod, Methyl, Ethyl, is-Propyl, n-Propyl, gegebenenfalls substituiertes Phenyl, Heteroaryl, Heterocyclyl, Cyclopropyl, Cyclobutyl, Cyclopentyl, Cyclohexyl, Methoxy, Ethoxy, Trifluormethyl, Difluormethyl, Trifluormethoxy, Methylthio, R 21 and R 22 independently of one another are hydrogen, fluorine, chlorine, bromine, iodine, methyl, ethyl, isopropyl, n-propyl, optionally substituted phenyl, heteroaryl, heterocyclyl, cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, methoxy, ethoxy, Trifluoromethyl, difluoromethyl, trifluoromethoxy, methylthio,
Trifluormethylthio, Hydroxycarbonyl, Methoxycarbonyl, Ethoxycarbonyl, n- Propyloxycarbonyl, iso-Propyloxycarbonyl, tert.-Butyloxycarbonyl,  Trifluoromethylthio, hydroxycarbonyl, methoxycarbonyl, ethoxycarbonyl, n-propyloxycarbonyl, isopropyloxycarbonyl, tert-butyloxycarbonyl,
Benzyloxycarbonyl, Cyclopropylmethoxycarbonyl, Allyloxycarbonyl,  Benzyloxycarbonyl, cyclopropylmethoxycarbonyl, allyloxycarbonyl,
Aminocarbonyl, Methylaminocarbonyl, Ethylaminocarbonyl, n- Propylaminocarbonyl, iso-Propylaminocarbonyl, Dimethylaminocarbonyl, Cyclopropylaminocarbonyl, Cyclobutylaminocarbonyl stehen,  Aminocarbonyl, methylaminocarbonyl, ethylaminocarbonyl, n-propylaminocarbonyl, iso-propylaminocarbonyl, dimethylaminocarbonyl, cyclopropylaminocarbonyl, cyclobutylaminocarbonyl,
R25, R26, R28 und R29 unabhängig voneinander für Wasserstoff, Methyl, Ethyl, n-Propyl, iso-Propyl, n-Butyl, tert.-Butyl, Cyclopropyl, Cyclobutyl, Cyclopentyl, Cyclohexyl, Fluor, Chlor, Brom, lod, gegebenenfalls substituiertes Phenyl, Heteroaryl, Heterocyclyl, Methoxy, Ethoxy, Trifluormethyl, Difluormethyl stehen, R 25 , R 26 , R 28 and R 29 independently of one another represent hydrogen, methyl, ethyl, n-propyl, isopropyl, n-butyl, tert-butyl, cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, fluorine, chlorine, bromine , iodine, optionally substituted phenyl, heteroaryl, heterocyclyl, methoxy, ethoxy, trifluoromethyl, difluoromethyl,
A8 für O (Sauerstoff), S (Schwefel), N-H, N-CH3, N-OCH3 oder die Gruppierung CHR27 steht und wobei R27 in der Gruppierung CHR27 die Bedeutung gemäß der nachstehenden Definition hat, A 8 is O (oxygen), S (sulfur), NH, N-CH 3, N -OCH 3 or the moiety CHR 27 and wherein R 27 in the moiety CHR 27 has the meaning as defined below,
R27 für Wasserstoff, Fluor, Chlor, Brom, lod, Methyl, Ethyl, is-Propyl, n-Propyl, R 27 is hydrogen, fluorine, chlorine, bromine, iodine, methyl, ethyl, isopropyl, n-propyl,
gegebenenfalls substituiertes Phenyl, Heteroaryl, Heterocyclyl, Cyclopropyl, Cyclobutyl, Cyclopentyl, Cyclohexyl, Methoxy, Ethoxy, Trifluormethyl,  optionally substituted phenyl, heteroaryl, heterocyclyl, cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, methoxy, ethoxy, trifluoromethyl,
Difluormethyl, Trifluormethoxy, Difluormethoxy, Methylthio, Trifluormethylthio, Hydroxycarbonyl, Methoxycarbonyl, Ethoxycarbonyl, n-Propyloxycarbonyl, iso- Propyloxycarbonyl, tert.-Butyloxycarbonyl, Benzyloxycarbonyl, Allyloxycarbonyl, Aminocarbonyl, Methylaminocarbonyl, Ethylaminocarbonyl, n- Propylaminocarbonyl, iso-Propylaminocarbonyl, Dimethylaminocarbonyl, Cyclopropylaminocarbonyl, Cyclobutylaminocarbonyl steht, Difluoromethyl, trifluoromethoxy, difluoromethoxy, methylthio, trifluoromethylthio, hydroxycarbonyl, methoxycarbonyl, ethoxycarbonyl, n-propyloxycarbonyl, isopropyloxycarbonyl, tert-butyloxycarbonyl, benzyloxycarbonyl, allyloxycarbonyl, aminocarbonyl, methylaminocarbonyl, ethylaminocarbonyl, n- Propylaminocarbonyl, iso-propylaminocarbonyl, dimethylaminocarbonyl, cyclopropylaminocarbonyl, cyclobutylaminocarbonyl,
R30, R31, R32, R34, R35 und R36 unabhängig voneinander für Wasserstoff, Methyl, Ethyl, n-Propyl, iso-Propyl, Fluor, Chlor, Brom, lod, Cyclopropyl, gegebenenfalls substituiertes Phenyl, Heteroaryl, Heterocyclyl, Methoxy, Ethoxy, n-Propyloxy, iso-Propyloxy, Trifluormethyl, Difluormethyl, Methylthio, Trifluormethylthio stehen. A9 für O (Sauerstoff), S (Schwefel), N-H, N-CH3, N-OCH3 oder die Gruppierung CHR steht und wobei R33 in der Gruppierung CHR33 die Bedeutung gemäß der nachstehenden Definition hat und R 30 , R 31 , R 32 , R 34 , R 35 and R 36 independently of one another are hydrogen, methyl, ethyl, n-propyl, isopropyl, fluorine, chlorine, bromine, iodine, cyclopropyl, optionally substituted phenyl, heteroaryl, Heterocyclyl, methoxy, ethoxy, n-propyloxy, iso-propyloxy, trifluoromethyl, difluoromethyl, methylthio, trifluoromethylthio. A 9 is O (oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the group CHR and wherein R 33 in the group CHR 33 has the meaning as defined below, and
R33 für Wasserstoff, Fluor, Chlor, Brom, lod, Methyl, Ethyl, is-Propyl, n-Propyl, R 33 is hydrogen, fluorine, chlorine, bromine, iodine, methyl, ethyl, isopropyl, n-propyl,
gegebenenfalls substituiertes Phenyl, Heteroaryl, Heterocyclyl, Cyclopropyl, optionally substituted phenyl, heteroaryl, heterocyclyl, cyclopropyl,
Cyclobutyl, Cyclopentyl, Cyclohexyl, Methoxy, Ethoxy, Trifluormethyl, Cyclobutyl, cyclopentyl, cyclohexyl, methoxy, ethoxy, trifluoromethyl,
Difluormethyl, Trifluormethoxy, Difluormethoxy, Methylthio, Trifluormethylthio, Hydroxycarbonyl, Methoxycarbonyl, Ethoxycarbonyl, n-Propyloxycarbonyl, iso- Propyloxycarbonyl, tert.-Butyloxycarbonyl, Benzyloxycarbonyl, Allyloxycarbonyl, Aminocarbonyl, Methylaminocarbonyl, Ethylaminocarbonyl, n- Difluoromethyl, trifluoromethoxy, difluoromethoxy, methylthio, trifluoromethylthio, hydroxycarbonyl, methoxycarbonyl, ethoxycarbonyl, n-propyloxycarbonyl, isopropyloxycarbonyl, tert-butyloxycarbonyl, benzyloxycarbonyl, allyloxycarbonyl, aminocarbonyl, methylaminocarbonyl, ethylaminocarbonyl, n-
Propylaminocarbonyl, iso-Propylaminocarbonyl, Dimethylaminocarbonyl, Cyclopropylaminocarbonyl, Cyclobutylaminocarbonyl steht. Propylaminocarbonyl, iso-propylaminocarbonyl, dimethylaminocarbonyl, cyclopropylaminocarbonyl, cyclobutylaminocarbonyl.
Im Hinblick auf die erfindungsgemäßen Verbindungen werden die vorstehend und weiter unten verwendeten Bezeichnungen erläutert. Diese sind dem Fachmann geläufig und haben insbesondere die im Folgenden erläuterten Bedeutungen: With regard to the compounds according to the invention, the terms used above and below are explained. These are familiar to the person skilled in the art and in particular have the meanings explained below:
Erfindungsgemäß steht "Arylsulfonyi" für gegebenenfalls substituiertes Phenylsulfonyl oder gegebenenfalls substituiertes polycyclisches Arylsulfonyi, hier insbesondere gegebenenfalls substituiertes Naphthyl-sulfonyl, beispielsweise substituiert durch Fluor, Chlor, Brom, lod, Cyano, Nitro, Alkyl-, Haloalkyl-, Haloalkoxy-, Amino-, According to the invention, "arylsulfonyi" is optionally substituted phenylsulfonyl or optionally substituted polycyclic arylsulfonyi, here in particular optionally substituted naphthylsulfonyl, for example substituted by fluorine, chlorine, bromine, iodine, cyano, nitro, alkyl, haloalkyl, haloalkoxy, amino,
Alkylamino-, Alkylcarbonylamino-, Dialkylamino- oder Alkoxy-gruppen. Alkylamino, alkylcarbonylamino, dialkylamino or alkoxy groups.
Erfindungsgemäß steht "Cycloalkylsulfonyl" - in Alleinstellung oder als Bestandteil einer chemischen Gruppe - für gegebenenfalls substituiertes Cycloalkylsulfonyl, vorzugsweise mit 3 bis 6 Kohlenstoffatomen wie beispielsweise Cyclopropylsulfonyl, Cyclobutylsulfonyl, Cyclopentylsulfonyl oder Cyclohexylsulfonyl. Erfindungsgemäß steht "Alkylsuifonyi" - in Alleinstellung oder als Bestandteil einer chemischen Gruppe - für geradkettiges oder verzweigtes Alkylsuifonyi, vorzugsweise mit 1 bis 8, oder mit 1 bis 6 Kohlenstoffatomen wie beispielsweise Methylsulfonyl, Ethylsulfonyl, n-Propylsulfonyl, Isopropylsulfonyl, n-Butylsulfonyl, Isobutylsulfonyl, sec- Butylsulfonyl und tert-Butylsulfonyl. According to the invention "cycloalkylsulfonyl" - in isolation or as a component a chemical group - optionally substituted cycloalkylsulfonyl, preferably having 3 to 6 carbon atoms such as cyclopropylsulfonyl, cyclobutylsulfonyl, cyclopentylsulfonyl or cyclohexylsulfonyl. According to the invention "alkylsuifonyi" - alone or as part of a chemical group - is straight-chain or branched Alkylsuifonyi, preferably having 1 to 8, or having 1 to 6 carbon atoms such as methylsulfonyl, ethylsulfonyl, n-propylsulfonyl, isopropylsulfonyl, n-butylsulfonyl, isobutylsulfonyl , sec-butylsulfonyl and tert-butylsulfonyl.
Erfindungsgemäß steht "Heteroarylsulfonyl" für gegebenenfalls substituiertes According to the invention "heteroarylsulfonyl" is optionally substituted
Pyridylsulfonyl, Pyrimidinylsulfonyl, Pyrazinylsulfonyl oder gegebenenfalls Pyridylsulfonyl, pyrimidinylsulfonyl, pyrazinylsulfonyl or optionally
substituiertes polycyclisches Heteroarylsulfonyl, hier insbesondere gegebenenfalls substituiertes Chinolinylsulfonyl, beispielsweise substituiert durch Fluor, Chlor, Brom, lod, Cyano, Nitro, Alkyl-, Haloalkyl-, Haloalkoxy-, Amino-, Alkylamino-, substituted polycyclic heteroarylsulfonyl, here in particular optionally substituted quinolinylsulfonyl, for example substituted by fluorine, chlorine, bromine, iodine, cyano, nitro, alkyl, haloalkyl, haloalkoxy, amino, alkylamino,
Alkylcarbonylamino-, Dialkylamino- oder Alkoxygruppen. Alkylcarbonylamino, dialkylamino or alkoxy groups.
Erfindungsgemäß steht "Alkylthio" - in Alleinstellung oder als Bestandteil einer chemischen Gruppe - für geradkettiges oder verzweigtes S-Alkyl, vorzugsweise mit 1 bis 8, oder mit 1 bis 6 Kohlenstoffatomen, wie beispielsweise Methylthio, Ethylthio, n- Propylthio, Isopropylthio, n-Butylthio, Isobutylthio, sec-Butylthio und tert-Butylthio. Alkenylthio bedeutet ein über ein Schwefelatom gebundenen Aikenylrest, Alkinylthio bedeutet ein über ein Schwefelatom gebundenen Alkinylrest, Cycloalkylthio bedeutet ein über ein Schwefelatom gebundenen Cycloalkyirest und Cycloalkenylthio bedeutet ein über ein Schwefelatom gebundenen Cycloalkenylrest. According to the invention, "alkylthio" - alone or as part of a chemical group - represents straight-chain or branched S-alkyl, preferably having 1 to 8, or having 1 to 6 carbon atoms, such as, for example, methylthio, ethylthio, n-propylthio, isopropylthio, n- Butylthio, isobutylthio, sec-butylthio and tert-butylthio. Alkenylthio means an akenyl radical bonded via a sulfur atom, alkynylthio means an alkynyl radical bonded via a sulfur atom, cycloalkylthio means a cycloalkyl radical bonded via a sulfur atom, and cycloalkenylthio means a cycloalkenyl radical bonded via a sulfur atom.
„Alkoxy" bedeutet ein über ein Sauerstoffatom gebundenen Alkylrest, Alkenyloxy bedeutet ein über ein Sauerstoffatom gebundenen Aikenylrest, Alkinyloxy bedeutet ein über ein Sauerstoffatom gebundenen Alkinylrest, Cycloalkyloxy bedeutet ein über ein Sauerstoffatom gebundenen Cycloalkyirest und Cycloaikenyioxy bedeutet ein über ein Sauerstoffatom gebundenen Cycloalkenylrest. "Alkoxy" denotes an alkyl radical bonded via an oxygen atom, alkenyloxy denotes an alkynyl radical bound via an oxygen atom, alkynyloxy denotes an alkynyl radical bound via an oxygen atom, cycloalkyloxy denotes a cycloalkyl radical bonded via an oxygen atom, and cycloalkylcyclopentyl denotes an cycloalkenyl radical bonded via an oxygen atom.
Der Begriff„Aryl" bedeutet ein gegebenenfalls substituiertes mono-, bi- oder polycyclisches aromatisches System mit vorzugsweise 6 bis 14, insbesondere 6 bis 10 Ring-C-Atomen, beispielsweise Phenyl, Naphthyl, Anthryl, Phenanthrenyl, und ähnliches, vorzugsweise Phenyl. The term "aryl" means an optionally substituted mono-, bi- or polycyclic aromatic system having preferably 6 to 14, in particular 6 to 10 Ring C atoms, for example, phenyl, naphthyl, anthryl, phenanthrenyl, and the like, preferably phenyl.
Vom Begriff„gegebenenfalls substituiertes Aryl" sind auch mehrcyclische Systeme, wie Tetrahydronaphtyl, Indenyl, Indanyl, Fluorenyl, Biphenylyl, umfasst, wobei die Bindungsstelle am aromatischen System ist. Von der Systematik her ist„Aryl" in der Regel auch von dem Begriff„gegebenenfalls substituiertes Phenyl" umfasst. The term "optionally substituted aryl" also includes polycyclic systems, such as tetrahydronaphthyl, indenyl, indanyl, fluorenyl, biphenylyl, the binding site being on the aromatic system. "Aryl" is also generally known from the term "optionally substituted phenyl ".
Bevorzugte Aryl-Substituenten sind hier zum Beispiel Wasserstoff, Halogen, Alkyl, Cycloalkyl, Cycloalkylalkyl, Cycloalkenyl, Halocycloalkyl, Alkenyl, Alkinyl, Aryl, Preferred aryl substituents here are, for example, hydrogen, halogen, alkyl, cycloalkyl, cycloalkylalkyl, cycloalkenyl, halocycloalkyl, alkenyl, alkynyl, aryl,
Arylalkyl, Arylalkenyl, Heteroaryl, Heteroarylalkyl, Heterocyclyl, Heterocyclylalkyl, Alkoxyalkyl, Alkylthio, Haloalkylthio, Haloalkyl, Alkoxy, Haloalkoxy, Cycloalkoxy, Cycloalkylalkoxy, Aryloxy, Heteroraryloxy, Alkoxyalkoxy, Alkinylalkoxy, Alkenyloxy, Bis- alkylaminoalkoxy, Tris-[alkyl]silyl, Bis-[alkyl]arylsilyl, Bis-[alkyl]alkylsilyl, Tris- [aikyljsilylalkinyl, Arylalkinyl, Heteroarylalkinyl, Alkylalkinyl, Cycloalkylalkinyl, Arylalkyl, arylalkenyl, heteroaryl, heteroarylalkyl, heterocyclyl, heterocyclylalkyl, alkoxyalkyl, alkylthio, haloalkylthio, haloalkyl, alkoxy, haloalkoxy, cycloalkoxy, cycloalkylalkoxy, aryloxy, heteroaryloxy, alkoxyalkoxy, alkynylalkoxy, alkenyloxy, bisalkylaminoalkoxy, tris [alkyl] silyl, bis [alkyl] arylsilyl, bis [alkyl] alkylsilyl, tris [aikylsilylalkynyl, arylalkynyl, heteroarylalkynyl, alkylalkynyl, cycloalkylalkynyl,
Haloalkylalkinyl, Heterocyclyl-N-alkoxy, Nitro, Cyano, Amino, Alkylamino, Bis- alkylamino, Alkylcarbonylamino, Cycloalkylcarbonylamino, Arylcarbonylamino, Alkoxycarbonylamino, Alkoxycarbonylalkylamino, Arylalkoxycarbonylalkylamino, Hydroxycarbonyl, Alkoxycarbonyl, Aminocarbonyl, Alkylaminocarbonyl, Haloalkylalkynyl, heterocyclyl-N-alkoxy, nitro, cyano, amino, alkylamino, bisalkylamino, alkylcarbonylamino, cycloalkylcarbonylamino, arylcarbonylamino, alkoxycarbonylamino, alkoxycarbonylalkylamino, arylalkoxycarbonylalkylamino, hydroxycarbonyl, alkoxycarbonyl, aminocarbonyl, alkylaminocarbonyl,
Cycloalkylaminocarbonyl, Bis-Alkylaminocarbonyl, Heteroarylalkoxy, Arylalkoxy Cycloalkylaminocarbonyl, bis-alkylaminocarbonyl, heteroarylalkoxy, arylalkoxy
Ein heterocyclischer Rest (Heterocyclyl) enthält mindestens einen heterocyclischen Ring (=carbocyclischer Ring, in dem mindestens ein C-Atom durch ein Heteroatom ersetzt ist, vorzugsweise durch ein Heteroatom aus der Gruppe N, O, S, P) der gesättigt, ungesättigt, teilgesättigt oder heteroaromatisch ist und dabei unsubstituiert oder substituiert sein kann, wobei die Bindungsstelle an einem Ringatom lokalisiert ist. Ist der Heterocyclylrest oder der heterocyclische Ring gegebenenfalls substituiert, kann er mit anderen carbocyclischen oder heterocyclischen Ringen anneliiert sein. Im Falle von gegebenenfalls substituiertem Heterocyclyl werden auch mehrcyclische Systeme umfaßt, wie beispielsweise 8-Aza-bicyclo[3.2.1 ]octanyl, 8-Aza- bicyclo[2.2.2]octanyl oder 1-Aza-bicyclo[2.2.1 ]heptyl. Im Falle von gegebenenfalls substituiertem Heterocyclyl werden auch spirocyclische Systeme umfaßt, wie beispielsweise 1 -Oxa-5-aza-spiro[2.3]hexyl. Wenn nicht anders definiert, enthält der heterocyclische Ring vorzugsweise 3 bis 9 Ringatome, insbesondere 3 bis 6 A heterocyclic radical (heterocyclyl) contains at least one heterocyclic ring (= carbocyclic ring in which at least one C atom is replaced by a heteroatom, preferably by a heteroatom from the group N, O, S, P) which is saturated, unsaturated, partially saturated or is heteroaromatic and may be unsubstituted or substituted, wherein the binding site is located on a ring atom. If the heterocyclyl or heterocyclic ring is optionally substituted, it may be annelated with other carbocyclic or heterocyclic rings. In the case of optionally substituted heterocyclyl, more cyclic systems are also included, for example 8-azabicyclo [3.2.1] octanyl, 8-azabicyclo [2.2.2] octanyl or 1-azabicyclo [2.2.1] heptyl. In the case of optionally substituted heterocyclyl, spirocyclic systems are also included, such as 1-oxa-5-aza-spiro [2.3] hexyl. Unless defined otherwise, the heterocyclic ring preferably contains 3 to 9 ring atoms, especially 3 to 6
Ringatome, und ein oder mehrere, vorzugsweise 1 bis 4, insbesondere 1 , 2 oder 3 Heteroatome im heterocyclischen Ring, vorzugsweise aus der Gruppe N, O, und S, wobei jedoch nicht zwei Sauerstoffatome direkt benachbart sein sollen, wie Ring atoms, and one or more, preferably 1 to 4, in particular 1, 2 or 3 Heteroatoms in the heterocyclic ring, preferably from the group N, O, and S, but not two oxygen atoms should be directly adjacent, such as
beispielsweise mit einem Heteroatom aus der Gruppe N, O und S 1 - oder 2- oder 3- Pyrrolidinyl, 3,4-Dihydro-2H-pyrrol-2- oder 3-yl, 2,3-Dihydro-1 H-pyrrol-1 - oder 2- oder 3- oder 4- oder 5-yl; 2,5-Dihydro-1 H-pyrrol-1 - oder 2- oder 3-yl, 1 - oder 2- oder 3- oder 4-Piperidinyl; 2.3,4.5-Tetrahydropyridin-2- oder 3- oder 4- oder 5-yl oder 6-yl; 1 ,2,3,6- Tetrahydropyridin-1 - oder 2- oder 3- oder 4- oder 5- oder 6-yl; 1 ,2,3.4- Tetrahydropyridin-1 - oder 2- oder 3- oder 4- oder 5- oder 6-yl; 1 ,4-Dihydropyridin-1 - oder 2- oder 3- oder 4-yl; 2,3-Dihydropyridin-2- oder 3- oder 4- oder 5- oder 6-yl; 2,5- Dihydropyridin-2- oder 3- oder 4- oder 5- oder 6-yl, 1 - oder 2- oder 3- oder 4-Azepanyl; 2,3,4,5-Tetrahydro-1 H-azepin-1 - oder 2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,3,4,7-Tetrahydro-1 H-azepin-1 - oder 2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2.3,6.7-Tetrahydro-1 H-azepin-1 - oder 2- oder 3- oder 4-yl; 3.4,5,6-Tetrahydro-2H- azepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 4.5-Dihydro-1 H-azepin-1 - oder 2- oder 3- oder 4-yl; 2.5-Dihydro-1 H-azepin-1 - oder -2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,7-Dihydro-1 H-azepin-1 - oder -2- oder 3- oder 4-yl; 2,3-Dihydro-1 H-azepin-for example with a heteroatom from the group N, O and S 1 - or 2- or 3-pyrrolidinyl, 3,4-dihydro-2H-pyrrol-2 or 3-yl, 2,3-dihydro-1 H-pyrrole 1 or 2 or 3 or 4 or 5-yl; 2,5-dihydro-1H-pyrrol-1 - or 2- or 3-yl, 1- or 2- or 3- or 4-piperidinyl; 2,3,4,5-tetrahydropyridine-2- or 3- or 4- or 5-yl or 6-yl; 1, 2,3,6-tetrahydropyridine-1 - or 2- or 3- or 4- or 5- or 6-yl; 1, 2,3,4-tetrahydropyridine-1 - or 2- or 3- or 4- or 5- or 6-yl; 1,4-dihydropyridine-1 - or 2- or 3- or 4-yl; 2,3-dihydropyridine-2- or 3- or 4- or 5- or 6-yl; 2,5-dihydropyridine-2- or 3- or 4- or 5- or 6-yl, 1- or 2- or 3- or 4-azepanyl; 2,3,4,5-tetrahydro-1H-azepine-1 - or 2- or 3- or 4- or 5- or 6- or 7-yl; 2,3,4,7-tetrahydro-1H-azepine-1 - or 2- or 3- or 4- or 5- or 6- or 7-yl; 2,3,6,7-tetrahydro-1H-azepine-1 - or 2- or 3- or 4-yl; 3,4,5,6-tetrahydro-2H-azepine-2 or 3 or 4 or 5 or 6 or 7-yl; 4,5-dihydro-1H-azepine-1 - or 2- or 3- or 4-yl; 2,5-dihydro-1H-azepine-1 or -2 or 3 or 4 or 5 or 6 or 7-yl; 2,7-dihydro-1H-azepine-1 - or -2- or 3- or 4-yl; 2,3-dihydro-1H-azepine
1 - oder -2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 3.4-Dihydro-2H-azepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 3,6-Dihydro-2H-azepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 5.6-Dihydro-2H-azepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 4,5-Dihydro-3H-azepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 1 H-Azepin-1 - oder -2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2H-Azepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 3H-Azepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 4H-Azepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl, 2- oder 3-Oxolanyl (= 2- oder 3-Tetrahydrofuranyl); 2 , 3- Di hyd rof u ra n-2- oder 3- oder 4- oder 5-yl; 2.5- Di hy d rof u ra n-2- oder 3-yl, 2- oder 3- oder 4-Oxanyl (= 2- oder 3- oder 4-Tetrahydropyranyl); 3,4-Dihydro-2H-pyran-2- oder 3- oder 4- oder 5- oder 6-yl; 3,6-Dihydro-2H-pyran-2- oder 3-oder 4- oder 5- oder 6-yl; 2H-Pyran-2- oder 3- oder 4- oder 5- oder 6-yl; 4H-Pyran-2- oder 3- oder 4-yl, 2- oder 3- oder 4-Oxepanyl; 2.3,4.5-Tetrahydrooxepin-2- oder 3- oder 4- oder 5- oder 6- oder 7- yl; 2,3.4,7-Tetrahydrooxepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,3,6,7- Tetrahydrooxepin-2- oder 3- oder 4-yl; 2.3-Dihydrooxepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 4,5-Dihydrooxepin-2- oder 3- oder 4-yl; 2.5-Dihydrooxepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; Oxepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl;1 - or -2 or 3 or 4 or 5 or 6 or 7-yl; 3,4-dihydro-2H-azepine-2 or 3 or 4 or 5 or 6 or 7-yl; 3,6-dihydro-2H-azepine-2 or 3 or 4 or 5 or 6 or 7-yl; 5.6-dihydro-2H-azepine-2- or 3- or 4- or 5- or 6- or 7-yl; 4,5-dihydro-3H-azepine-2 or 3 or 4 or 5 or 6 or 7-yl; 1 H-azepine-1 or -2 or 3 or 4 or 5 or 6 or 7-yl; 2H-azepine-2- or 3- or 4- or 5- or 6- or 7-yl; 3H-azepine-2- or 3- or 4- or 5- or 6- or 7-yl; 4H-azepine-2- or 3- or 4- or 5- or 6- or 7-yl, 2- or 3-oxolanyl (= 2- or 3-tetrahydrofuranyl); 2,3-dihydrogen, 2- or 3- or 4- or 5-yl; 2.5-dehydro-2- or 3-yl, 2- or 3- or 4-oxanyl (= 2- or 3- or 4-tetrahydropyranyl); 3,4-dihydro-2H-pyran-2 or 3 or 4 or 5 or 6-yl; 3,6-dihydro-2H-pyran-2 or 3 or 4 or 5 or 6-yl; 2H-pyran-2- or 3- or 4- or 5- or 6-yl; 4H-pyran-2- or 3- or 4-yl, 2- or 3- or 4-oxepanyl; 2,3,4,5-tetrahydrooxepin-2 or 3 or 4 or 5 or 6 or 7 yl; 2,3,4,7-tetrahydrooxepin-2 or 3 or 4 or 5 or 6 or 7-yl; 2,3,6,7-tetrahydrooxepin-2 or 3 or 4-yl; 2,3-dihydrooxepin-2 or 3 or 4 or 5 or 6 or 7-yl; 4,5-dihydrooxepin-2 or 3 or 4-yl; 2,5-dihydrooxepin-2 or 3 or 4 or 5 or 6 or 7-yl; Oxepin-2 or 3 or 4 or 5 or 6 or 7-yl;
2- oder 3-Tetrahydrothiophenyl; 2,3-Dihydrothiophen-2- oder 3- oder 4- oder 5-yl; 2,5- Dihydrothiophen-2- oder 3-yl; Tetrahydro-2H-thiopyran-2- oder 3- oder 4-yl; 3,4- Dihydro-2H-thiopyran-2- oder 3- oder 4- oder 5- oder 6-yl; 3,6-Dihydro-2H-thiopyran-2- or 3-tetrahydrothiophenyl; 2,3-dihydrothiophene-2 or 3 or 4 or 5-yl; 2,5-dihydrothiophene-2 or 3-yl; Tetrahydro-2H-thiopyran-2- or 3- or 4-yl; 3,4- Dihydro-2H-thiopyran-2 or 3 or 4 or 5 or 6-yl; 3,6-dihydro-2H-thiopyran
2- oder 3- oder 4- oder 5- oder 6-yl; 2H-Thiopyran-2- oder 3- oder 4- oder 5- oder 6-yl; 4H-Thiopyran-2- oder 3- oder 4-yl. Bevorzugte 3-Ring und 4-Ring-Heterocyclen sind beispielsweise 1 - oder 2-Aziridinyl, Oxiranyl, Thiiranyl, 1 - oder 2- oder 3-Azetidinyl, 2- oder 3-Oxetanyl, 2- oder 3-Thietanyl, 1 ,3-Dioxetan-2-yl. Weitere Beispiele für 2- or 3- or 4- or 5- or 6-yl; 2H-thiopyran-2 or 3 or 4 or 5 or 6-yl; 4H-thiopyran-2- or 3- or 4-yl. Preferred 3-membered and 4-membered heterocycles are, for example, 1- or 2-aziridinyl, oxiranyl, thiiranyl, 1- or 2- or 3-azetidinyl, 2- or 3-oxetanyl, 2- or 3-thietanyl, 1,3 -Dioxetan-2-yl. Further examples of
"Heterocyclyl" sind ein partiell oder vollständig hydrierter heterocyclischer Rest mit zwei Heteroatomen aus der Gruppe N, O und S, wie beispielsweise 1 - oder 2- oder 3- oder 4-Pyrazolidinyl; 4.5-Dihydro-3H-pyrazol- 3- oder 4- oder 5-yl; 4,5-Dihydro-1 H- pyrazol-1- oder 3- oder 4- oder 5-yl; 2.3-Dihydro-1 H-pyrazol-1 - oder 2- oder 3- oder 4- oder 5-yl; 1 - oder 2- oder 3- oder 4- Imidazolidinyl; 2.3-Dihydro-1 H-imidazol-1 - oder 2- oder 3- oder 4-yl; 2,5-Dihydro-1 H-imidazol-1 - oder 2- oder 4- oder 5-yl; 4,5-Dihydro- 1 H-imidazol-1 - oder 2- oder 4- oder 5-yl; Hexahydropyridazin-1 - oder 2- oder 3- oder 4-yl; 1 ,2.3,4-Tetrahydropyridazin-1 - oder 2- oder 3- oder 4- oder 5- oder 6-yl; 1 ,2,3,6- Tetrahydropyridazin-1 - oder 2- oder 3- oder 4- oder 5- oder 6-yl; 1 ,4,5.6- Tetrahydropyridazin-1 - oder 3- oder 4- oder 5- oder 6-yl; 3,4,5,6-Tetrahydropyridazin- "Heterocyclyl" are a partially or fully hydrogenated heterocyclic radical having two heteroatoms from the group N, O and S, such as 1- or 2- or 3- or 4-pyrazolidinyl; 4,5-dihydro-3H-pyrazole-3- or 4- or 5-yl; 4,5-dihydro-1H-pyrazole-1 or 3 or 4 or 5-yl; 2,3-dihydro-1H-pyrazole-1 - or 2- or 3- or 4- or 5-yl; 1- or 2- or 3- or 4-imidazolidinyl; 2,3-dihydro-1H-imidazole-1 - or 2- or 3- or 4-yl; 2,5-dihydro-1H-imidazole-1 - or 2- or 4- or 5-yl; 4,5-dihydro-1H-imidazole-1 - or 2- or 4- or 5-yl; Hexahydropyridazine-1 - or 2- or 3- or 4-yl; 1, 2,3,4-tetrahydropyridazine-1 - or 2- or 3- or 4- or 5- or 6-yl; 1, 2,3,6-tetrahydropyridazine-1 - or 2- or 3- or 4- or 5- or 6-yl; 1, 4,5,6-tetrahydropyridazine-1 - or 3- or 4- or 5- or 6-yl; 3,4,5,6-Tetrahydropyridazin-
3- oder 4- oder 5-yl; 4,5-Dihydropyridazin-3- oder 4-yl; 3.4-Dihydropyridazin-3- oder 4- oder 5- oder 6-yl; 3,6-Dihydropyridazin-3- oder 4-yl; 1 ,6-Dihydropyriazin-1 - oder 3- oder 4- oder 5- oder 6-yl; Hexahydropyrimidin-1 - oder 2- oder 3- oder 4-yl; 1 ,4.5,6- Tetrahydropyrimidin-1 - oder 2- oder 4- oder 5- oder 6-yl; 1 .2,5,6-Tetrahydropyrimidin- 1 - oder 2- oder 4- oder 5- oder 6-yl; 1 ,2,3,4-Tetrahydropyrimidin-1- oder 2- oder 3- oder 4- oder 5- oder 6-yl; 1 ,6-Dihydropyrimidin-1 - oder 2- oder 4- oder 5- oder 6-yl;3- or 4- or 5-yl; 4,5-dihydropyridazine-3 or 4-yl; 3,4-dihydropyridazine-3- or 4- or 5- or 6-yl; 3,6-dihydropyridazine-3 or 4-yl; 1,6-dihydropyriazine-1 - or 3- or 4- or 5- or 6-yl; Hexahydropyrimidine-1 - or 2- or 3- or 4-yl; 1, 4.5, 6-tetrahydropyrimidine-1 - or 2- or 4- or 5- or 6-yl; 1, 2, 5, 6-tetrahydropyrimidine-1 or 2 or 4 or 5 or 6-yl; 1,2,3,4-tetrahydropyrimidine-1 or 2 or 3 or 4 or 5 or 6-yl; 1,6-dihydropyrimidine-1 - or 2- or 4- or 5- or 6-yl;
1 .2- Dihydropyrimidin-1 - oder 2- oder 4- oder 5- oder 6-yl; 2,5-Dihydropyrimidin-2- oder1, 2-dihydropyrimidine-1 - or 2- or 4- or 5- or 6-yl; 2,5-dihydropyrimidine-2- or
4- oder 5-yl; 4,5-Dihydropyrimidin- 4- oder 5- oder 6-yl; 1 ,4-Dihydropyrimidin-1 - oder 2- oder 4- oder 5- oder 6-yl; 1- oder 2- oder 3-Piperazinyl; 1 ,2,3,6-Tetrahydropyrazin-1- oder 2- oder 3- oder 5- oder 6-yl; 1 ,2.3.4-Tetrahydropyrazin-1 - oder 2- oder 3- oder 4- oder 5- oder 6-yl; 1 ,2-Dihydropyrazin-1- oder 2- oder 3- oder 5- oder 6-yl; 1 ,4- Dihydropyrazin-1 - oder 2- oder 3-yl; 2.3-Dihydropyrazin-2- oder 3- oder 5- oder 6-yl; 2,5-Dihydropyrazin-2- oder 3-yl; 1 ,3-Dioxolan-2- oder 4- oder 5-yl; 1 ,3-Dioxol-2- oder 4-yl; 1 .3-Dioxan-2- oder 4- oder 5-yl; 4H-1 ,3-Dioxin-2- oder 4- oder 5- oder 6-yl; 1 ,4- Dioxan-2- oder 3- oder 5- oder 6-yl; 2,3-Dihydro-1 ,4-dioxin-2- oder 3- oder 5- oder 6-yl; 1 ,4-Dioxin-2- oder 3-yl; 1 ,2-Dithiolan-3- oder 4-yl; 3H-1 .2-Dithiol-3- oder 4- oder 5-yl;4- or 5-yl; 4,5-dihydropyrimidine-4- or 5- or 6-yl; 1,4-dihydropyrimidine-1 - or 2- or 4- or 5- or 6-yl; 1- or 2- or 3-piperazinyl; 1, 2,3,6-tetrahydropyrazine-1 or 2 or 3 or 5 or 6-yl; 1, 2.3.4-tetrahydropyrazine-1 - or 2- or 3- or 4- or 5- or 6-yl; 1,2-dihydropyrazine-1- or 2- or 3- or 5- or 6-yl; 1,4-dihydropyrazine-1 - or 2- or 3-yl; 2,3-dihydropyrazine-2- or 3- or 5- or 6-yl; 2,5-dihydropyrazine-2 or 3-yl; 1,3-dioxolane-2- or 4- or 5-yl; 1,3-dioxol-2- or 4-yl; 1, 3-dioxan-2 or 4 or 5-yl; 4H-1, 3-dioxin-2 or 4 or 5 or 6-yl; 1, 4-dioxane-2 or 3 or 5 or 6-yl; 2,3-dihydro-1,4-dioxin-2- or 3- or 5- or 6-yl; 1, 4-dioxin-2 or 3-yl; 1,2-dithiolan-3 or 4-yl; 3H-1,2-dithiol-3- or 4- or 5-yl;
1 .3- Dithiolan-2- oder 4-yl; 1 ,3-Dithiol-2- oder 4-yl; 1 ,2-Dithian-3- oder 4-yl; 3.4-Dihydro- 1 ,2-dithiin-3- oder 4- oder 5- oder 6-yl; 3,6-Dihydro-1 ,2-dithiin-3- oder 4-yl; 1 ,2-Dithiin- 3- oder 4-yl; 1 ,3-Dithian-2- oder 4- oder 5-yl; 4H-1 ,3-Dithiin-2- oder 4- oder 5- oder 6- yl; lsoxazolidin-2- oder 3- oder 4- oder 5-yl; 2,3-Dihydroisoxazol-2- oder 3- oder 4- oder 5-yl; 2,5-Dihydroisoxazol-2- oder 3- oder 4- oder 5-yl; 4.5-Dihydroisoxazol-3- oder1, 3-dithiolan-2 or 4-yl; 1,3-dithiol-2- or 4-yl; 1,2-dithian-3 or 4-yl; 3,4-dihydro-1,2-dithiin-3- or 4- or 5- or 6-yl; 3,6-dihydro-1,2-dithiin-3 or 4-yl; 1,2-dithiine-3 or 4-yl; 1,3-dithian-2- or 4- or 5-yl; 4H-1, 3-dithiine-2 or 4 or 5 or 6 yl; Isoxazolidine-2 or 3 or 4 or 5-yl; 2,3-dihydroisoxazole-2 or 3 or 4 or 5-yl; 2,5-dihydroisoxazole-2 or 3 or 4 or 5-yl; 4.5-dihydroisoxazole-3-Or
4- oder 5-yl; 1 ,3-Oxazolidin-2- oder 3- oder 4- oder 5-yl; 2,3-Dihydro-1 ,3-oxazol-2- oder4- or 5-yl; 1,3-oxazolidine-2- or 3- or 4- or 5-yl; 2,3-dihydro-1,3-oxazole-2-or
3- oder 4- oder 5-yl; 2,5-Dihydro-1 ,3-oxazol-2- oder 4- oder 5-yl; 4,5-Dihydro-1 ,3- oxazol-2- oder 4- oder 5-yl; 1 ,2-Oxazinan-2- oder 3- oder 4- oder 5- oder 6-yl; 3.4-3- or 4- or 5-yl; 2,5-dihydro-1,3-oxazol-2- or 4- or 5-yl; 4,5-dihydro-1,3-oxazol-2 or 4 or 5-yl; 1, 2-oxazinan-2 or 3 or 4 or 5 or 6-yl; 3.4-
Dihydro-2H-1 ,2-oxazin-2- oder 3- oder 4- oder 5- oder 6-yl; 3,6-Dihydro-2H-1 .2-oxazin- 2- oder 3- oder 4- oder 5- oder 6-yl; 5,6-Dihydro-2H-1 .2-oxazin-2- oder 3- oder 4- oderDihydro-2H-1,2-oxazine-2- or 3- or 4- or 5- or 6-yl; 3,6-dihydro-2H-1, 2-oxazine-2- or 3- or 4- or 5- or 6-yl; 5,6-dihydro-2H-1, 2-oxazine-2 or 3 or 4 or
5- oder 6-yl; 5.6-Dihydro-4H-1 ,2-oxazin-3- oder 4- oder 5- oder 6-yl; 2H-1 ,2-Oxazin-2- oder 3- oder 4- oder 5- oder 6-yl; 6H-1 ,2-Oxazin-3- oder 4- oder 5- oder 6-yl; 4H-1 ,2- Oxazin-3- oder 4- oder 5- oder 6-yl; 1 .3-Oxazinan-2- oder 3- oder 4- oder 5- oder 6-yl; 3,4-Dihydro-2H-1 ,3-oxazin-2- oder 3- oder 4- oder 5- oder 6-yl; 3,6-Dihydro-2H-1 .3- oxazin-2- oder 3- oder 4- oder 5- oder 6-yl; 5,6-Dihydro-2H-1 ,3-oxazin-2- oder 4- oder 5- oder 6-yl; 5,6-Dihydro-4H-1 ,3-oxazin-2- oder 4- oder 5- oder 6-yl; 2H-1 ,3-Oxazin-2- oder 4- oder 5- oder 6-yl; 6H-1 ,3-Oxazin-2- oder 4- oder 5- oder 6-yl; 4H-1 ,3-Oxazin-2- oder 4- oder 5- oder 6-yl; Morpholin-2- oder 3- oder 4-yl; 3,4-Dihydro-2H-1 ,4-oxazin-2- oder 3- oder 4- oder 5- oder 6-yl; 3,6-Dihydro-2H-1 ,4-oxazin-2- oder 3- oder 5- oder 6- yl; 2H-1 ,4-oxazin-2- oder 3- oder 5- oder 6-yl; 4H-1 ,4-oxazin-2- oder 3-yl; 1 ,2- Oxazepan-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2.3,4,5-Tetrahydro-1 ,2- oxazepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,3,4,7-Tetrahydro-1 ,2-oxazepin- 2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,3,6,7-Tetrahydro-1 .2-oxazepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,5,6,7-Teirahydro-1 ,2-oxazepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 4,5,6,7-Tetrahydro-1 ,2-oxazepin-3- oder 4- oder 5- oder 6- oder 7-yl; 2,3-Dihydro-1 ,2-oxazepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,5- Dihydro-1 ,2-oxazepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,7-Dihydro-1 ,2- oxazepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 4,5-Dihydro-1 ,2-oxazepin-3- oder5- or 6-yl; 5.6-dihydro-4H-1,2-oxazine-3- or 4- or 5- or 6-yl; 2H-1, 2-oxazine-2 or 3 or 4 or 5 or 6-yl; 6H-1, 2-oxazine-3 or 4 or 5 or 6-yl; 4H-1, 2-oxazine-3 or 4 or 5 or 6-yl; 1, 3-oxazinan-2 or 3 or 4 or 5 or 6-yl; 3,4-dihydro-2H-1,3-oxazine-2- or 3- or 4- or 5- or 6-yl; 3,6-dihydro-2H-1, 3-oxazine-2 or 3 or 4 or 5 or 6-yl; 5,6-dihydro-2H-1,3-oxazine-2- or 4- or 5- or 6-yl; 5,6-dihydro-4H-1,3-oxazine-2- or 4- or 5- or 6-yl; 2H-1, 3-oxazine-2- or 4- or 5- or 6-yl; 6H-1, 3-oxazine-2 or 4 or 5 or 6-yl; 4H-1, 3-oxazine-2 or 4 or 5 or 6-yl; Morpholine-2- or 3- or 4-yl; 3,4-dihydro-2H-1,4-oxazine-2- or 3- or 4- or 5- or 6-yl; 3,6-dihydro-2H-1,4-oxazine-2 or 3 or 5 or 6-yl; 2H-1,4-oxazine-2- or 3- or 5- or 6-yl; 4H-1,4-oxazine-2 or 3-yl; 1, 2- oxazepan-2- or 3- or 4- or 5- or 6- or 7-yl; 2,3,4,5-tetrahydro-1, 2-oxazepine-2 or 3 or 4 or 5 or 6 or 7-yl; 2,3,4,7-tetrahydro-1,2-oxazepine 2- or 3- or 4- or 5- or 6- or 7-yl; 2,3,6,7-tetrahydro-1, 2-oxazepine-2 or 3 or 4 or 5 or 6 or 7-yl; 2,5,6,7-Teirahydro-1,2-oxazepine-2- or 3- or 4- or 5- or 6- or 7-yl; 4,5,6,7-tetrahydro-1,2-oxazepine-3- or 4- or 5- or 6- or 7-yl; 2,3-dihydro-1,2-oxazepine-2- or 3- or 4- or 5- or 6- or 7-yl; 2,5-dihydro-1,2-oxazepine-2- or 3- or 4- or 5- or 6- or 7-yl; 2,7-dihydro-1, 2-oxazepine-2 or 3 or 4 or 5 or 6 or 7-yl; 4,5-dihydro-1,2-oxazepine-3 or
4- oder 5- oder 6- oder 7-yl; 4.7-Dihydro-1 ,2-oxazepin-3- oder 4- oder 5- oder 6- oder 7-yl; 6,7-Dihydro-1 .2-oxazepin-3- oder 4- oder 5- oder 6- oder 7-yl; 1 ,2-Oxazepin-3- oder 4- oder 5- oder 6- oder 7-yl; 1 ,3-Oxazepan-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,3,4, 5-Tetrahydro-1 ,3-oxazepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,3.4.7-Tetrahydro-1 ,3-oxazepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,3,6.7- Tetrahydro-1 ,3-oxazepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2.5.6,7- Tetrahydro-1 ,3-oxazepin-2- oder 4- oder 5- oder 6- oder 7-yl; 4.5.6.7-Tetrahydro-1 ,3- oxazepin-2- oder 4- oder 5- oder 6- oder 7-yl; 2,3-Dihydro-1 ,3-oxazepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,5-Dihydro-1 ,3-oxazepin-2- oder 4- oder 5- oder 6- oder 7-yl; 2,7-Dihydro-1 ,3-oxazepin-2- oder 4- oder 5- oder 6- oder 7-yl; 4,5-Dihydro-1 ,3- oxazepin-2- oder 4- oder 5- oder 6- oder 7-yl; 4,7-Dihydro-1 ,3-oxazepin-2- oder 4- oder4- or 5- or 6- or 7-yl; 4.7-dihydro-1,2-oxazepine-3- or 4- or 5- or 6- or 7-yl; 6,7-dihydro-1, 2-oxazepine-3 or 4 or 5 or 6 or 7-yl; 1,2-oxazepine-3- or 4- or 5- or 6- or 7-yl; 1,3-oxazepan-2- or 3- or 4- or 5- or 6- or 7-yl; 2,3,4,5-tetrahydro-1,3-oxazepine-2- or 3- or 4- or 5- or 6- or 7-yl; 2,3,4,7-tetrahydro-1,3-oxazepine-2- or 3- or 4- or 5- or 6- or 7-yl; 2,3,6,7-tetrahydro-1,3-oxazepine-2- or 3- or 4- or 5- or 6- or 7-yl; 2.5.6,7-tetrahydro-1,3-oxazepine-2- or 4- or 5- or 6- or 7-yl; 4.5.6.7-tetrahydro-1,3,10-oxazepine-2- or 4- or 5- or 6- or 7-yl; 2,3-dihydro-1,3-oxazepine-2- or 3- or 4- or 5- or 6- or 7-yl; 2,5-dihydro-1,3-oxazepine-2 or 4 or 5 or 6 or 7-yl; 2,7-dihydro-1,3-oxazepine-2- or 4- or 5- or 6- or 7-yl; 4,5-dihydro-1,3-oxazepine-2- or 4- or 5- or 6- or 7-yl; 4,7-dihydro-1,3-oxazepine-2- or 4- or
5- oder 6- oder 7-yl; 6,7-Dihydro-1 ,3-oxazepin-2- oder 4- oder 5- oder 6- oder 7-yl; 1 .3-Oxazepin-2- oder 4- oder 5- oder 6- oder 7-yl; 1 ,4-Oxazepan-2- oder 3- oder 5- oder 6- oder 7-yl; 2,3,4, 5-Tetrahydro-1 ,4-oxazepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,3,4,7-Tetrahydro-1 ,4-oxazepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,3,6,7-Tetrahydro-1 ,4-oxazepin-2- oder 3- oder 5- oder 6- oder 7-yl; 2,5,6.7- Tetrahydro-1 ,4-oxazepin-2- oder 3- oder 5- oder 6- oder 7-yl; 4,5,6,7-Tetrahydro-1 ,4- oxazepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,3-Dihydro-1 ,4-oxazepin-2- oder 3- oder 5- oder 6- oder 7-yl; 2,5-Dihydro-1 ,4-oxazepin-2- oder 3- oder 5- oder 6- oder 7-yl; 2,7-Dihydro-1 ,4-oxazepin-2- oder 3- oder 5- oder 6- oder 7-yl; 4,5-Dihydro-1 ,4- oxazepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 4,7-Dihydro-1 ,4-oxazepin-2- oder5- or 6- or 7-yl; 6,7-dihydro-1,3-oxazepine-2- or 4- or 5- or 6- or 7-yl; 1, 3-oxazepine-2 or 4 or 5 or 6 or 7-yl; 1,4-oxazepan-2- or 3- or 5- or 6- or 7-yl; 2,3,4,5-tetrahydro-1,4-oxazepine-2- or 3- or 4- or 5- or 6- or 7-yl; 2,3,4,7-tetrahydro-1,4-oxazepine-2- or 3- or 4- or 5- or 6- or 7-yl; 2,3,6,7-tetrahydro-1,4-oxazepine-2- or 3- or 5- or 6- or 7-yl; 2,5,6,7-tetrahydro-1,4-oxazepine-2- or 3- or 5- or 6- or 7-yl; 4,5,6,7-tetrahydro-1, 4-oxazepine-2 or 3 or 4 or 5 or 6 or 7-yl; 2,3-dihydro-1,4-oxazepine-2- or 3- or 5- or 6- or 7-yl; 2,5-dihydro-1,4-oxazepine-2- or 3- or 5- or 6- or 7-yl; 2,7-dihydro-1,4-oxazepine-2- or 3- or 5- or 6- or 7-yl; 4,5-dihydro-1,4-oxazepine-2- or 3- or 4- or 5- or 6- or 7-yl; 4,7-Dihydro-1,4-oxazepine-2-Or
3- oder 4- oder 5- oder 6- oder 7-yl; 6,7-Dihydro-1 ,4-oxazepin-2- oder 3- oder 5- oder3- or 4- or 5- or 6- or 7-yl; 6,7-dihydro-1, 4-oxazepine-2 or 3 or 5 or
6- oder 7-yl; 1 ,4-Oxazepin-2- oder 3- oder 5- oder 6- oder 7-yl; lsothiazolidin-2- oder 3- oder 4- oder 5-yl; 2,3-Dihydroisothiazol-2- oder 3- oder 4- oder 5-yl; 2.5-6- or 7-yl; 1,4-oxazepine-2- or 3- or 5- or 6- or 7-yl; isothiazolidine-2- or 3- or 4- or 5-yl; 2,3-dihydroisothiazole-2- or 3- or 4- or 5-yl; 2.5-
Dihydroisothiazol-2- oder 3- oder 4- oder 5-yl; 4,5-Dihydroisothiazol-3- oder 4- oder 5- yl; 1 ,3-Thiazolidin-2- oder 3- oder 4- oder 5-yl; 2.3-Dihydro-1 ,3-thiazol-2- oder 3- oderDihydroisothiazole-2- or 3- or 4- or 5-yl; 4,5-dihydroisothiazole-3 or 4 or 5-yl; 1,3-thiazolidine-2- or 3- or 4- or 5-yl; 2,3-dihydro-1, 3-thiazole-2 or 3 or
4- oder 5-yl; 2,5-Dihydro-1 ,3-thiazol-2- oder 4- oder 5-yl; 4,5-Dihydro-1 ,3-thiazol-2- oder 4- oder 5-yl; 1 ,3-Thiazinan-2- oder 3- oder 4- oder 5- oder 6-yl; 3,4-Dihydro-2H- 1 ,3-thiazin-2- oder 3- oder 4- oder 5- oder 6-yl; 3,6-Dihydro-2H-1 ,3-thiazin-2- oder 3- oder 4- oder 5- oder 6-yl; 5,6-Dihydro-2H-1 ,3-thiazin-2- oder 4- oder 5- oder 6-yl; 5.6- Dihydro-4H-1 .3-thiazin-2- oder 4- oder 5- oder 6-yl; 2H-1 ,3-Thiazin-2- oder 4- oder 5- oder 6-yl; 6H-1 ,3-Thiazin-2- oder 4- oder 5- oder 6-yl; 4H-1 ,3-Thiazin-2- oder 4- oder4- or 5-yl; 2,5-dihydro-1,3-thiazole-2 or 4 or 5-yl; 4,5-dihydro-1,3-thiazole-2- or 4- or 5-yl; 1, 3-thiazinan-2 or 3 or 4 or 5 or 6-yl; 3,4-dihydro-2H-1, 3-thiazine-2 or 3 or 4 or 5 or 6-yl; 3,6-dihydro-2H-1, 3-thiazine-2 or 3 or 4 or 5 or 6-yl; 5,6-dihydro-2H-1, 3-thiazine-2 or 4 or 5 or 6-yl; 5.6-dihydro-4H-1, 3-thiazine-2 or 4 or 5 or 6-yl; 2H-1, 3-thiazine-2 or 4 or 5 or 6-yl; 6H-1, 3-thiazine-2 or 4 or 5 or 6-yl; 4H-1, 3-thiazine-2 or 4 or
5- oder 6-yl. Weitere Beispiele für "Heterocyclyl" sind ein partiell oder vollständig hydrierter heterocyclischer Rest mit 3 Heteroatomen aus der Gruppe N, O und S, wie beispielsweise 1 ,4.2-Dioxazolidin-2- oder 3- oder 5-yl; 1 ,4,2-Dioxazol-3- oder 5-yl; 1 ,4.2-Dioxazinan-2- oder -3- oder 5- oder 6-yl; 5,6-Dihydro-1 ,4.2-dioxazin-3- oder 5- oder 6-yl; 1 ,4.2-Dioxazin-3- oder 5- oder 6-yl; 1 ,4,2-Dioxazepan-2- oder 3- oder 5- oder5- or 6-yl. Further examples of "heterocyclyl" are a partially or fully hydrogenated heterocyclic radical having 3 heteroatoms from the group consisting of N, O and S, such as 1,2,2-dioxazolidin-2- or 3- or 5-yl; 1, 4,2-dioxazol-3 or 5-yl; 1,2,2-dioxazinan-2- or -3- or 5- or 6-yl; 5,6-dihydro-1,2,2-dioxazine-3- or 5- or 6-yl; 1, 4.2-dioxazine-3- or 5- or 6-yl; 1, 4,2-Dioxazepan-2 or 3 or 5 or
6- oder 7-yl; 6,7-Dihydro-5H-1 ,4.2-Dioxazepin-3- oder 5- oder 6- oder 7-yl; 2.3- Dihydro-7H-1 ,4.2-Dioxazepin-2- oder 3- oder 5- oder 6- oder 7-yl; 2,3-Dihydro-5H-6- or 7-yl; 6,7-dihydro-5H-1, 4.2-dioxazepine-3 or 5 or 6 or 7-yl; 2.3-dihydro-7H-1, 4.2-dioxazepine-2- or 3- or 5- or 6- or 7-yl; 2,3-dihydro-5H-
1 ,4,2-Dioxazepin-2- oder 3- oder 5- oder 6- oder 7-yl; 5H-1 ,4,2-Dioxazepin-3- oder 5- oder 6- oder 7-yl; 7H-1 ,4,2-Dioxazepin-3- oder 5- oder 6- oder 7-yl. Strukturbeispiele für gegebenenfalls weiter substituierte Heterocyclen sind auch im Folgenden aufgeführt: 1,2,2-dioxazepine-2- or 3- or 5- or 6- or 7-yl; 5H-1, 4,2-dioxazepine-3 or 5 or 6 or 7-yl; 7H-1, 4,2-dioxazepine-3 or 5 or 6 or 7-yl. Structural examples of optionally further substituted heterocycles are also listed below:
Die oben aufgeführten Heterocyclen sind bevorzugt beispielsweise durch Wasserstoff, Halogen, Alkyl, Haloalkyl, Hydroxy, Alkoxy, Cycloalkoxy, Aryloxy, Alkoxyalkyl, The heterocycles listed above are preferably, for example, hydrogen, halogen, alkyl, haloalkyl, hydroxy, alkoxy, cycloalkoxy, aryloxy, alkoxyalkyl,
Alkoxyalkoxy, Cycloalkyl, Halocycloalkyl, Aryl, Arylalkyl, Heteroaryl, Heterocyclyl, Alkenyl, Alkylcarbonyl, Cycloalkylcarbonyl, Arylcarbonyl, Heteroarylcarbonyl, Alkoxyalkoxy, cycloalkyl, halocycloalkyl, aryl, arylalkyl, heteroaryl, heterocyclyl, alkenyl, alkylcarbonyl, cycloalkylcarbonyl, arylcarbonyl, heteroarylcarbonyl,
Alkoxycarbonyl, Hydroxycarbonyl, Cycloalkoxy carbonyl, Cycloalkylalkoxycarbonyl, Alkoxy carbonylalkyl, Arylalkoxycarbonyl, Arylalkoxycarbonylalkyl, Alkinyl, Alkinylalkyl, Alkylalkinyl, Tris-alkylsilylalkinyl, Nitro, Amino, Cyano, Haloalkoxy, Haloalkylthio, Alkylthio, Hydrothio, Hydroxyalkyl, Oxo, Heteroarylalkoxy, Arylalkoxy,  Alkoxycarbonyl, hydroxycarbonyl, cycloalkoxycarbonyl, cycloalkylalkoxycarbonyl, alkoxycarbonylalkyl, arylalkoxycarbonyl, arylalkoxycarbonylalkyl, alkynyl, alkynylalkyl, alkylalkynyl, trisalkylsilylalkynyl, nitro, amino, cyano, haloalkoxy, haloalkylthio, alkylthio, hydrothio, hydroxyalkyl, oxo, heteroarylalkoxy, arylalkoxy,
Heterocyclylalkoxy, Heterocyclylalkylthio, Heterocyclyloxy, Heterocyclylthio, Heterocyclylalkoxy, heterocyclylalkylthio, heterocyclyloxy, heterocyclylthio,
Heteroaryloxy, Bis-alkylamino, Alkylamino, Cycloalkylamino, Heteroaryloxy, bis-alkylamino, alkylamino, cycloalkylamino,
Hydroxycarbonylalkylamino, Alkoxycarbonylalkylamino, Arylalkoxycarbonylalkylamino, Alkoxycarbonylalkyl(alkyl)amino, Aminocarbonyl, Alkylaminocarbonyl, Bis- alkylaminocarbonyl, Cycloalkylaminocarbonyl, Hydroxycarbonylalkylaminocarbonyl, Alkoxycarbonylalkylaminocarbonyl, Arylalkoxycarbonylalkylaminocarbonyl substituiert.  Hydroxycarbonylalkylamino, alkoxycarbonylalkylamino, arylalkoxycarbonylalkylamino, alkoxycarbonylalkyl (alkyl) amino, aminocarbonyl, alkylaminocarbonyl, bis-alkylaminocarbonyl, cycloalkylaminocarbonyl, hydroxycarbonylalkylaminocarbonyl, alkoxycarbonylalkylaminocarbonyl, arylalkoxycarbonylalkylaminocarbonyl.
Wenn ein Grundkörper "durch einen oder mehrere Reste" aus einer Aufzählung von Resten (= Gruppe) oder einer generisch definierten Gruppe von Resten substituiert ist, so schließt dies jeweils die gleichzeitige Substitution durch mehrere gleiche und/oder strukturell unterschiedliche Reste ein. If a main body is "substituted by one or more radicals" from an enumeration of radicals (= group) or a generically defined group of radicals, this includes the simultaneous substitution by a plurality of identical and / or structurally different radicals.
Handelt es sich es sich um einen teilweise oder vollständig gesättigten Stickstoff- Heterocyclus, so kann dieser sowohl über Kohlenstoff als auch über den Stickstoff mit dem Rest des Moleküls verknüpft sein. If it is a partially or fully saturated nitrogen heterocycle, it may be linked to the rest of the molecule via both carbon and nitrogen.
Als Substituenten für einen substituierten heterocyclischen Rest kommen die weiter unten genannten Substituenten in Frage, zusätzlich auch Oxo und Thioxo. Die Suitable substituents for a substituted heterocyclic radical are the substituents mentioned below, in addition to oxo and thioxo. The
Oxogruppe als Substituent an einem Ring-C-Atom bedeutet dann beispielsweise eine Carbonylgruppe im heterocyclischen Ring. Dadurch sind vorzugsweise auch Lactone und Lactame umfasst. Die Oxogruppe kann auch an den Heteroringatomen, die in verschiedenen Oxidationsstufen existieren können, z.B. bei N und S, auftreten und bilden dann beispielsweise die divalenten Gruppen N(O) , S(O) (auch kurz SO) und S(0)2 (auch kurz S02) im heterocyclischen Ring. Im Fall von -N(O)- und -S(O)- Gruppen sind jeweils beide Enantiomere umfasst. Oxo group as a substituent on a ring C atom then means, for example, a carbonyl group in the heterocyclic ring. As a result, lactones are preferably also and lactams. The oxo group can also occur at the hetero ring atoms, which can exist in different oxidation states, for example at N and S, and then form, for example, the divalent groups N (O), S (O) (also SO for short) and S (O) 2 ( also briefly S02) in the heterocyclic ring. In the case of -N (O) and -S (O) groups, both enantiomers are included.
Erfindungsgemäß steht der Ausdruck„Heteroaryl" für heteroaromatische According to the invention, the term "heteroaryl" is heteroaromatic
Verbindungen, d. h. vollständig ungesättigte aromatische heterocyclische Compounds, d. H. fully unsaturated aromatic heterocyclic
Verbindungen, vorzugsweise für 5- bis 7-gliedrige Ringe mit 1 bis 4, vorzugsweise 1 oder 2 gleichen oder verschiedenen Heteroatomen, vorzugsweise O, S oder N. Compounds, preferably for 5- to 7-membered rings having 1 to 4, preferably 1 or 2 identical or different heteroatoms, preferably O, S or N.
Erfindungsgemäße Heteroaryle sind beispielsweise 1 H-Pyrrol-1 -yl; 1 H-Pyrrol-2-yl; 1 H- Pyrrol-3-yl; Furan-2-yl; Furan-3-yl; Thien-2-yl; Thien-3-yl, 1 H-lmidazol-1 -yl; 1 H- lmidazol-2-yl; 1 H-lmidazol-4-yl; 1 H-lmidazol-5-yl; 1 H-Pyrazol-1 -yl; 1 H-Pyrazol-3-yl; 1 H- Pyrazol-4-yl; 1 H-Pyrazol-5-yi, 1 H-1 ,2,3-Triazol-1 -yl, 1 H-1 ,2,3-Triazol-4-yl, 1 H-1 , 2,3- Triazol-5-yl, 2H-1 ,2.3-Triazol-2-yl, 2H-1 ,2,3-Triazol-4-yl, 1 H-1 ,2.4-Triazol-1 -yl, 1 H- 1 ,2,4-Triazol-3-yl, 4H-1 .2,4-Triazol-4-yl, 1 .2,4-Oxadiazol-3-yl, 1 ,2,4-Oxadiazol-5-yl, 1 .3.4-Oxadiazol-2-yl, 1 ,2.3-Oxadiazol-4-yl, 1 ,2.3-Oxadiazol-5-yl, 1 ,2,5-Oxadiazol-3-yl, Azepinyl, Pyridin-2-yl, Pyridin-3-yl, Pyridin-4-yl, Pyrazin-2-yl, Pyrazin-3-yl, Pyrimidin-2- yl, Pyrimidin-4-yl, Pyrimidin-5-yl, Pyridazin-3-yl, Pyridazin-4-yl, 1 ,3,5-Triazin-2-yl, 1 ,2,4- Triazin-3-yl, 1 ,2,4-Triazin-5-yl, 1 ,2.4-Triazin-6-yl, 1 ,2,3-Triazin-4-yl, 1 ,2,3-Triazin-5-yl, 1 ,2,4-, 1 .3,2-, 1 ,3,6- und 1 .2,6-Oxazinyl, lsoxazol-3-yl, lsoxazol-4-yl, lsoxazol-5-yl, 1 ,3- Oxazol-2-yl, 1 .3-Oxazol-4-yl, 1 .3-Oxazol-5-yl, lsothiazol-3-yl, lsothiazol-4-yl, Isothiazol- 5-yl, 1 .3-Thiazol-2-yl, 1 .3-Thiazol-4-yl, 1 ,3-Thiazol-5-yl, Oxepinyl, Thiepinyl, 1 ,2,4- Triazolonyl und 1 .2,4-Diazepinyl, 2H-1 ,2,3,4-Tetrazol-5-yl, 1 H-1 ,2.3.4-Tetrazol-5-yl, 1 .2,3.4-Oxatriazol-5-yl, 1 ,2,3.4-Thiatriazol-5-yl, 1 ,2,3,5-Oxatriazol-4-yl, 1 ,2.3,5- Heteroaryls of the invention are, for example, 1H-pyrrol-1-yl; 1H-pyrrol-2-yl; 1H-pyrrol-3-yl; Furan-2-yl; Furan-3-yl; Thien-2-yl; Thien-3-yl, 1H-imidazole-1-yl; 1 H-imidazol-2-yl; 1 H -imidazol-4-yl; 1 H -imidazol-5-yl; 1H-pyrazole-1-yl; 1H-pyrazol-3-yl; 1H-pyrazol-4-yl; 1 H-pyrazol-5-yl, 1 H-1, 2,3-triazol-1-yl, 1 H-1, 2,3-triazol-4-yl, 1 H-1, 2,3-triazole 5-yl, 2H-1, 2,3-triazol-2-yl, 2H-1, 2,3-triazol-4-yl, 1H-1, 2,4-triazol-1-yl, 1H-1, 2, 4-triazol-3-yl, 4H-1,2,4-triazol-4-yl, 1, 2, 4-oxadiazol-3-yl, 1, 2,4-oxadiazol-5-yl, 1 .3.4- Oxadiazol-2-yl, 1, 2.3-oxadiazol-4-yl, 1, 2.3-oxadiazol-5-yl, 1, 2,5-oxadiazol-3-yl, azepinyl, pyridin-2-yl, pyridine-3 yl, pyridin-4-yl, pyrazine-2-yl, pyrazine-3-yl, pyrimidin-2-yl, pyrimidin-4-yl, pyrimidin-5-yl, pyridazin-3-yl, pyridazin-4-yl, 1, 3,5-triazin-2-yl, 1, 2,4-triazin-3-yl, 1, 2,4-triazin-5-yl, 1, 2,4-triazin-6-yl, 1, 2, 3-triazin-4-yl, 1, 2,3-triazin-5-yl, 1, 2,4-, 1, 3, 2, 1, 3, 6 and 1, 2, 6-oxazinyl, isoxazole 3-yl, isoxazol-4-yl, isoxazol-5-yl, 1,3-oxazol-2-yl, 1, 3-oxazol-4-yl, 1, 3-oxazol-5-yl, isothiazole-3 -yl, isothiazol-4-yl, isothiazol-5-yl, 1, 3-thiazol-2-yl, 1, 3-thiazol-4-yl, 1, 3-thiazol-5-yl, oxepinyl, thiepinyl, 1 , 2,4-triazolonyl and 1, 2, 4-diazepinyl, 2H-1, 2,3,4-tetrazol-5-yl, 1H-1, 2,3,4-tetrazol-5-yl, 1, 2, 3, 4-oxatriazol-5-yl, 1, 2,3,4-thiatriazol-5-yl, 1, 2,3,5-oxatriazol-4-yl, 1, 2.3,5-
Thiatriazol-4-yl. Die erfindungsgemäßen Heteroarylgruppen können ferner mit einem oder mehreren, gleichen oder verschiedenen Resten substituiert sein. Sind zwei benachbarte Kohlenstoffatome Bestandteil eines weiteren aromatischen Rings, so handelt es sich um anneliierte heteroaromatische Systeme, wie benzokondensierte oder mehrfach annellierte Heteroaromaten. Bevorzugt sind beispielsweise Chinoline (z. B. Chinolin-2-yl, Chinolin-3-yl, Chinolin-4-yl, Chinolin-5-yl, Chinolin-6-yl, Chinolin-7- yl, Chinolin-8-yl); Isochinoline (z. B. lsochinolin-1 -yl, lsochinolin-3-yl, lsochinolin-4-yl, lsochinolin-5-yl, lsochinolin-6-yl, lsochinolin-7-yl, lsochinolin-8-yl); Chinoxalin; Thiatriazole-4-yl. The heteroaryl groups according to the invention may furthermore be substituted by one or more identical or different radicals. If two adjacent carbon atoms are part of another aromatic ring, these are annelated heteroaromatic systems, such as benzo-fused or multiply fused heteroaromatics. Preference is given, for example, to quinolines (for example quinolin-2-yl, quinolin-3-yl, quinolin-4-yl, quinolin-5-yl, quinolin-6-yl, quinolin-7-yl, quinolin-8-yl ); Isoquinolines (e.g., isoquinolin-1-yl, isoquinolin-3-yl, isoquinolin-4-yl, isoquinolin-5-yl, isoquinolin-6-yl, isoquinolin-7-yl, isoquinolin-8-yl); quinoxaline;
Chinazolin; Cinnolin; 1 ,5-Naphthyridin; 1 .6-Naphthyridin; 1 ,7-Naphthyridin; 1 .8- Naphthyridin; 2,6-Naphthyridin; 2,7-Naphthyridin; Phthalazin; Pyridopyrazine; quinazoline; cinnoline; 1,5-naphthyridine; 1, 6-naphthyridine; 1,7-naphthyridine; 1 .8- naphthyridine; 2,6-naphthyridine; 2,7-naphthyridine; phthalazine; Pyridopyrazine;
Pyridopyrimidine; Pyridopyridazine; Pteridine; Pyrimidopyrimidine. Beispiele für Heteroaryl sind auch 5- oder 6-gliedrige benzokondensierte Ringe aus der Gruppe 1 H- lndol-1 -yl, 1 H-lndol-2-yl, 1 H-lndol-3-yl, 1 H-lndol-4-yl, 1 H-lndol-5-yl, 1 H-lndol-6-yl, 1 H- lndol-7-yl, 1 -Benzofuran-2-yl, 1 -Benzofuran-3-yl, 1 -Benzofuran-4-yl, 1-Benzofuran-5-yl, 1 -Benzofuran-6-yl, 1 -Benzofuran-7-yl, 1 -Benzothiophen-2-yl, 1 -Benzothiophen-3-yl, 1 - Benzothiophen-4-yl, 1 -Benzothiophen-5-yl, 1 -Benzothiophen-6-yl, 1 -Benzothiophen-7- yl, 1 H-lndazol-1 -yl, 1 H-lndazol-3-yl, 1 H-lndazol-4-yl, 1 H-lndazol-5-yl, 1 H-lndazol-6-yl, 1 H-lndazol-7-yl, 2H-lndazol-2-yl, 2H-lndazol-3-yl, 2H-lndazol-4-yl, 2H-lndazol-5-yl. 2H- lndazol-6-yl, 2H-lndazol-7-yl, 2H-lsoindol-2-yl, 2H-lsoindol-1 -yl, 2H-lsoindol-3-yl, 2H- lsoindol-4-yl, 2H-lsoindol-5-yl, 2H-lsoindol-6-yl; 2H-lsoindol-7-yl, 1 H-Benzimidazoi-1 -yl, 1 H-Benzimidazol-2-yl, 1 H-Benzimidazol-4-yl, 1 H-Benzimidazol-5-yl, 1 H-Benzimidazol- 6-yl, 1 H-Benzimidazol-7-yl, 1 ,3-Benzoxazol-2-yl, 1 ,3-Benzoxazol-4-yl, 1 ,3-Benzoxazol- 5-yl, 1 .3-Benzoxazol-6-yl, 1 .3-Benzoxazol-7-yl, 1 ,3-Benzthiazol-2-yl, 1 ,3-Benzthiazol-4- yl, 1 .3-Benzthiazol-5-yl. 1 ,3-Benzthiazol-6-yl, 1 .3-Benzthiazol-7-yl, 1 .2-Benzisoxazol-3- yl, 1 ,2-Benzisoxazol-4-yl, 1 ,2-Benzisoxazol-5-yl, 1 ,2-Benzisoxazol-6-yl, 1 ,2- Benzisoxazol-7-yl, 1 ,2-Benzisothiazol-3-yl, 1 ,2-Benzisothiazol-4-yl, 1 ,2-Benzisothiazol- 5-yl, 1 ,2-Benzisothiazol-6-yl, 1 ,2-Benzisothiazol-7-yl. Die Bezeichnung "Halogen" bedeutet beispielsweise Fluor, Chlor, Brom oder lod. Wird die Bezeichnung für einen Rest verwendet, dann bedeutet "Halogen" beispielsweise ein Fluor-, Chlor-, Brom- oder lodatom. pyridopyrimidines; Pyridopyridazine; pteridines; Pyrimidopyrimidine. Examples of heteroaryl are also 5- or 6-membered benzo-fused rings from the group 1H-indol-1-yl, 1H-indol-2-yl, 1H-indol-3-yl, 1H-indole-4 yl, 1H-indol-5-yl, 1H-indol-6-yl, 1H-indol-7-yl, 1-benzofuran-2-yl, 1-benzofuran-3-yl, 1-benzofuran-4 -yl, 1-benzofuran-5-yl, 1-benzofuran-6-yl, 1-benzofuran-7-yl, 1-benzothiophen-2-yl, 1-benzothiophen-3-yl, 1-benzothiophen-4-yl , 1-benzothiophene-5-yl, 1-benzothiophene-6-yl, 1-benzothiophene-7-yl, 1-indazol-1-yl, 1-indazol-3-yl, 1-indazole-4-yl yl, 1H-indazol-5-yl, 1H-indazol-6-yl, 1H-indazol-7-yl, 2H-indazol-2-yl, 2H-indazol-3-yl, 2H-indazole-4 -yl, 2H-indazol-5-yl. 2H-indazol-6-yl, 2H-indazol-7-yl, 2H-isoindol-2-yl, 2H-isoindol-1-yl, 2H-isoindol-3-yl, 2H-isoindol-4-yl, 2H- isoindol-5-yl, 2H-isoindol-6-yl; 2H-isoindol-7-yl, 1H-benzimidazol-1-yl, 1H-benzimidazol-2-yl, 1H-benzimidazol-4-yl, 1H-benzimidazol-5-yl, 1H-benzimidazole-6 -yl, 1H-benzimidazol-7-yl, 1,3-benzoxazol-2-yl, 1,3-benzoxazol-4-yl, 1,3-benzoxazol-5-yl, 1, 3-benzoxazole-6 yl, 1, 3-Benzoxazol-7-yl, 1, 3-benzthiazol-2-yl, 1, 3-benzthiazol-4-yl, 1, 3-benzthiazol-5-yl. 1, 3-benzthiazol-6-yl, 1, 3-benzthiazol-7-yl, 1, 2-benzisoxazol-3-yl, 1, 2-benzisoxazol-4-yl, 1, 2-benzisoxazol-5-yl, 1, 2-Benzisoxazol-6-yl, 1,2-benzisoxazol-7-yl, 1,2-benzisothiazol-3-yl, 1,2-benzisothiazol-4-yl, 1,2-benzisothiazol-5-yl, 1,2-benzisothiazol-6-yl, 1,2-benzisothiazol-7-yl. The term "halogen" means, for example, fluorine, chlorine, bromine or iodine. When the term for a group is used, "halogen" means, for example, a fluorine, chlorine, bromine or iodine atom.
Erfindungsgemäß bedeutet„Alkyl" einen geradkettigen oder verzweigten offen kettigen, gesättigten Kohlenwasserstoffrest, der gegebenenfalls ein- oder mehrfach substituiert ist. Bevorzugte Substituenten sind Halogenatome, Alkoxy-, Haloalkoxy-, Cyano-, Alkylthio, Haloalkylthio-, Amino- oder Nitrogruppen, besonders bevorzugt sind According to the invention, "alkyl" means a straight-chain or branched open-chain, saturated hydrocarbon radical which is optionally monosubstituted or polysubstituted Preferred substituents are halogen atoms, alkoxy, haloalkoxy, cyano, alkylthio, haloalkylthio, amino or nitro groups, more preferably are
Methoxy, Methyl, Fluoralkyl, Cyano, Nitro, Fluor, Chlor, Brom oder lod. „Haloalkyl", ,,-alkenyl" und ,,-alkinyl" bedeuten durch gleiche oder verschiedene Methoxy, methyl, fluoroalkyl, cyano, nitro, fluoro, chloro, bromo or iodo. "Haloalkyl", "- alkenyl" and "alkynyl" mean the same or different
Halogenatome, teilweise oder vollständig substituiertes Alkyl, Alkenyl bzw. Alkinyl, z.B. Monohaloalkyl (= Monohalogenalkyl) wie z. B. CH2CH2CI, CH2CH2Br, CHCICH3, CH2CI, CH2F; Perhaloalkyl wie z. B. CCI3, CCIF2, CFCI2,CF2CCIF2. CF2CCIFCF3; Polyhaloalkyl wie z. B. CH2CHFCI, CF2CCIFH, CF2CBrFH, CH2CF3; Der Begriff Perhaloalkyl umfasst dabei auch den Begriff Perfluoralkyl. Halogen atoms, partially or fully substituted alkyl, alkenyl or alkynyl, for example monohaloalkyl (= monohaloalkyl) such. CH 2 CH 2 Cl, CH 2 CH 2 Br, CHCICH 3 , CH 2 Cl, CH 2 F; Perhaloalkyl such. CCI 3 , CCIF 2 , CFCI 2 , CF 2 CCIF 2 . CF 2 CCIFCF 3 ; Polyhaloalkyl such. B. CH2CHFCI, CF2CCIFH, CF 2 CBrFH, CH2CF3; The term perhaloalkyl also encompasses the term perfluoroalkyl.
Teilfiuoriertes Alkyl bedeutet einen geradkettigen oder verzweigten, gesättigten Kohlenwasserstoff, der einfach oder mehrfach durch Fluor substituiert ist, wobei sich die entsprechenden Fluoratome als Substituenten an einem oder mehreren Partially fluorinated alkyl means a straight-chain or branched, saturated hydrocarbon which is monosubstituted or polysubstituted by fluorine, the corresponding fluorine atoms being present as substituents on one or more
verschiedenen Kohlenstoffatomen der geradkettigen oder verzweigten different carbon atoms of the straight-chain or branched
Kohlenwasserstoffkette befinden können, wie z. B. CHFCH3, CH2CH2F, CH2CH2CF3, CHF2, CH2F, CHFCF2CF3 Hydrocarbon chain can be located, such as. B. CHFCH3, CH2CH2F, CH2CH2CF3, CHF 2, CH 2 F, CHFCF2CF3
Teilfluoriertes Haloalkyl bedeutet einen geradkettigen oder verzweigten, gesättigten Kohlenwasserstoff, der durch verschiedenene Halogenatomen mit mindestens einem Fluoratom substituiert ist, wobei alle anderen gegebenenfalls vorhandenen Partially fluorinated haloalkyl means a straight-chain or branched, saturated hydrocarbon which is substituted by various halogen atoms having at least one fluorine atom, all other optionally present
Halogenatome ausgewählt sind aus der Gruppe Fluor, Chlor oder Brom, lod. Die entsprechenden Halogenatome können sich dabei als Substituenten an einem oder mehreren verschiedenen Kohlenstoffatomen der geradkettigen oder verzweigten Kohlenwasserstoffkette befinden. Teilfluoriertes Haloalkyl schließt auch die Halogen atoms are selected from the group fluorine, chlorine or bromine, iodine. The corresponding halogen atoms may be present as substituents on one or more different carbon atoms of the straight-chain or branched hydrocarbon chain. Partially fluorinated haloalkyl also includes the
vollständige Substitution der geradkettigen oder verzweigten Kette durch Halogen unter Beteiligung von mindestens einem Fluoratom ein. complete substitution of the straight-chain or branched chain by halogen with the participation of at least one fluorine atom.
Haloalkoxy ist z.B. OCF3, OCHF2, OCH2F, OCF2CF3, OCH2CF3 und OCH2CH2CI; Entsprechendes gilt für Haloalkenyl und andere durch Halogen substituierten Reste. Haloalkoxy is eg OCF 3 , OCHF 2 , OCH 2 F, OCF 2 CF 3 , OCH 2 CF 3 and OCH 2 CH 2 Cl; The same applies to haloalkenyl and other halogen-substituted radicals.
Der hier beispielhaft genannte Ausdruck "(C1-C4)- Alkyl" bedeutet eine The term "(C 1 -C 4) -alkyl" exemplified herein means a
Kurzschreibweise für geradkettiges oder verzweigtes Alkyl mit einem bis 4 Short notation for straight-chain or branched alkyl having one to four
Kohlenstoffatomen entsprechend der Bereichsangabe für C-Atome, d. h. umfasst die Reste Methyl, Ethyl, 1 -Propyl, 2-Propyl, 1 -Butyl, 2-Butyl, 2-Methylpropyl oder tert-Butyl Allgemeine Alkylreste mit einem größeren angegebenen Bereich von C-Atomen, z. B. "(Ci-Ce)- Alkyl", umfassen entsprechend auch geradkettige oder verzweigte Alkylreste mit einer größeren Zahl von C-Atomen, d. h. gemäß Beispiel auch die Alkylreste mit 5 und 6 C-Atomen.  Carbon atoms corresponding to the range for C atoms, d. H. includes the radicals methyl, ethyl, 1-propyl, 2-propyl, 1-butyl, 2-butyl, 2-methylpropyl or tert-butyl General alkyl radicals having a larger specified range of carbon atoms, eg. B. "(Ci-Ce) - alkyl", accordingly also include straight-chain or branched alkyl radicals having a larger number of C atoms, d. H. according to example, the alkyl radicals with 5 and 6 carbon atoms.
Wenn nicht speziell angegeben, sind bei den Kohlenwasserstoffresten wie Alkyl-, Alkenyl- und Alkinylresten, auch in zusammengesetzten Resten, die niederen Kohlenstoffgerüste, z.B. mit 1 bis 6 C- Atomen bzw. bei ungesättigten Gruppen mit 2 bis 6 C-Atomen, bevorzugt. Alkylreste, auch in den zusammengesetzten Resten wie Alkoxy, Haloalkyl usw., bedeuten z.B. Methyl, Ethyl, n- oder i-Propyl, n-, i-, t- oder 2-Butyl, Pentyle, Hexyle, wie n-Hexyl, i-Hexyl und 1 .3-Dimethylbutyl, Heptyle, wie n-Heptyl, 1-Methylhexyl und 1 ,4-Dimethylpentyl; Alkenyl- und Alkinylreste haben die Bedeutung der den Alkyiresten entsprechenden möglichen ungesättigten Reste, wobei mindestens eine Doppelbindung bzw. Dreifachbindung enthalten ist. Bevorzugt sind Reste mit einer Doppelbindung bzw. Dreifachbindung. Der Begriff„Alkenyl" schließt insbesondere auch geradkettige oder verzweigte offenkettige Kohlenwasserstoffreste mit mehr als einer Doppelbindung ein, wie 1 .3- Butadienyl und 1 ,4-Pentadienyl, aber auch Allenyl- oder Kumulenyl-reste mit einer bzw. mehreren kumulierten Doppelbindungen, wie beispielsweise Allenyl (1 ,2- Propadienyl), 1 .2-Butadienyi und 1 ,2,3-Pentatrienyl. Alkenyl bedeutet z.B. Vinyl, welches ggf. durch weitere Alkylreste substituiert sein kann, z.B. Prop-1 -en-1-yl, But-1 - en-1 -yl, Allyl, 1-Methyl-prop-2-en-1 -yl, 2-Methyl-prop-2-en-1 -yl, But-2-en-1-yl, 1 - Methyl-but-3-en-1-yl und 1 -Methyl-but-2-en-1 -yl, 2-Methyl-prop-1 -en-1 -yl, Unless specifically stated, the hydrocarbon radicals such as alkyl, alkenyl and alkynyl radicals, even in assembled radicals, are lower Carbon skeletons, for example having 1 to 6 carbon atoms or in unsaturated groups having 2 to 6 carbon atoms, are preferred. Alkyl radicals, including in the assembled radicals such as alkoxy, haloalkyl, etc., mean, for example, methyl, ethyl, n- or i-propyl, n-, i-, t- or 2-butyl, pentyls, hexyls, such as n-hexyl, i -Hexyl and 1, 3-dimethylbutyl, heptyls, such as n-heptyl, 1-methylhexyl and 1, 4-dimethylpentyl; Alkenyl and alkynyl radicals have the meaning of the possible unsaturated radicals corresponding to the alkyl radicals, wherein at least one double bond or triple bond is contained. Preference is given to radicals having a double bond or triple bond. In particular, the term "alkenyl" also includes straight-chain or branched open-chain hydrocarbon radicals having more than one double bond, such as 1, 3-butadienyl and 1, 4-pentadienyl, but also allenyl or cumulenyl radicals having one or more cumulative double bonds, such as for example allenyl (1,2-propadienyl), 1,2-butadienyl and 1,2,3-pentatrienyl.Alkenyl is, for example, vinyl, which may optionally be substituted by further alkyl radicals, for example prop-1-en-1-yl, But-1 - en-1-yl, allyl, 1-methyl-prop-2-en-1-yl, 2-methyl-prop-2-en-1-yl, but-2-en-1-yl, 1-methylbut-3-en-1-yl and 1-methylbut-2-en-1-yl, 2-methyl-prop-1 -ene-1-yl,
1 -Methylpro p-1 -en-1 -yl, 1 -Methylprop-2-en-1 -yl, 2-Methyl-prop-2-en-1 -yl, But-2-en-1 -yl, But-3-en-1 -yl, 1-Methyl-but-3-en-1-yl oder 1 -Methyl-but-2-en-1 -yl, Pentenyl, 1-methylpro p-1 -ene-1-yl, 1-methylprop-2-en-1-yl, 2-methyl-prop-2-en-1-yl, but-2-en-1-yl, but 3-en-1-yl, 1-methyl-but-3-en-1-yl or 1-methylbut-2-en-1-yl, pentenyl,
2-Methylpentenyl oder Hexenyl. 2-methylpentenyl or hexenyl.
Der Begriff„Alkinyl" schließt insbesondere auch geradkettige oder verzweigte offenkettige Kohlenwasserstoffreste mit mehr als einer Dreifachbindung oder auch mit einer oder mehreren Dreifachbindungen und einer oder mehreren Doppelbindungen ein, wie beispielsweise 1 ,3-Butatrienyl bzw. 3-Penten-1 -in-1 -yl. (C2-Ce)-Alkinyl bedeutet beispielsweise Ethinyl, Propargyl, 1 -Methyl-prop-2-in-1 -yl, 2-Butinyl, The term "alkynyl" in particular also includes straight-chain or branched open-chain hydrocarbon radicals having more than one triple bond or else having one or more triple bonds and one or more double bonds, for example 1,3-butatrienyl or 3-penten-1-yn-1 -yl. (C 2 -C 6) -alkynyl, for example, is ethynyl, propargyl, 1-methyl-prop-2-yn-1-yl, 2-butynyl,
2-Pentinyl oder 2-Hexinyl, vorzugsweise Propargyl, But-2-in-1 -yl, But-3-in-1 -yl oder 1 -Methyl-but-3-in-1 -yl. Der Begriff„Cycloalkyl" bedeutet ein carbocyclisches, gesättigtes Ringsystem mit vorzugsweise 3-8 Ring-C-Atomen, z.B. Cyclopropyl, Cyclobutyl, Cyclopentyl oder Cyclohexyl. Im Falle von gegebenenfalls substituiertem Cycloalkyl werden cyclische Systeme mit Substituenten umfasst, wobei auch Substituenten mit einer 2-pentynyl or 2-hexynyl, preferably propargyl, but-2-yn-1-yl, but-3-yn-1-yl or 1-methylbut-3-yn-1-yl. The term "cycloalkyl" means a carbocyclic saturated ring system preferably having 3-8 ring C atoms, e.g., cyclopropyl, cyclobutyl, cyclopentyl, or cyclohexyl In the case of optionally substituted cycloalkyl, cyclic systems having substituents are also included wherein substituents also have one
Doppelbindung am Cycloalkylrest, z. B. eine Alkylidengruppe wie Methyliden, umfasst sind. Im Falle von gegebenenfalls substituiertem Cycloalkyl werden auch Double bond on the cycloalkyl, z. An alkylidene group such as methylidene are. In the case of optionally substituted cycloalkyl also become
mehrcyclische aliphatische Systeme umfaßt, wie beispielsweise Bicyclo[1 .1 .0]butan-1 - yl, Bicyclo[1 .1 .0]butan-2-yl, Bicyclo[2.1 .0]pentan-1 -yl, Bicyclo[2.1 .0]pentan-2-yl, Bicyclo[2.1 .0]pentan-5-yl, Bicyclo[2.2.1 ]hept-2-yl (Norbornyl), Bicyclo[2.2.2]octan-2-yl, Adamantan-1 -yl und Adamantan-2-yl. Der Ausdruck "(C3-C7)-Cycloalkyl" bedeutet eine Kurzschreibweise für Cycloalkyl mit drei bis 7 Kohlenstoffatomen entsprechend der Bereichsangabe für C-Atome. polycyclic aliphatic systems such as, for example, bicyclo [1, 1] -butan-1-yl, bicyclo [1, 1] -butan-2-yl, bicyclo [2.1.0] pentan-1-yl, bicyclo [2.1 .0] pentan-2-yl, bicyclo [2.1.0] pentan-5-yl, bicyclo [2.2.1] hept-2-yl (norbornyl), bicyclo [2.2.2] octan-2-yl, adamantane 1 -yl and adamantan-2-yl. The term "(C3-C7) cycloalkyl" means a shorthand notation for cycloalkyl having from three to seven carbon atoms corresponding to the range of C atoms.
Im Falle von substituiertem Cycloalkyl werden auch spirocyclische aliphatische Systeme umfaßt, wie beispielsweise Spiro[2.2]pent-1 -yl, Spiro[2.3]hex-1 -yl, In the case of substituted cycloalkyl, spirocyclic aliphatic systems are also included, such as spiro [2.2] pent-1-yl, spiro [2.3] hex-1-yl,
Spiro[2.3]hex-4-yl, 3-Spiro[2.3]hex-5-yl. Spiro [2.3] hex-4-yl, 3-spiro [2.3] hex-5-yl.
„Cycioaikenyl" bedeutet ein carbocyciisches, nicht aromatisches, partiell ungesättigtes Ringsystem mit vorzugsweise 4-8 C-Atomen, z.B. 1 -Cyclobutenyl, 2-Cyclobutenyl, 1- Cyclopentenyl, 2-Cyclopentenyl, 3-Cyclopentenyl, oder 1 -Cyclohexenyl, 2-"Cycioalkylcyclic" means a carbocyclic, non-aromatic, partially unsaturated ring system preferably having 4-8 C atoms, for example 1-cyclobutenyl, 2-cyclobutenyl, 1-cyclopentenyl, 2-cyclopentenyl, 3-cyclopentenyl, or 1-cyclohexenyl, 2-
Cyclohexenyl, 3-Cyclohexenyl, 1 .3-Cyclohexadienyl oder 1 ,4-Cyclohexadienyl, wobei auch Substituenten mit einer Doppelbindung am Cycloalkenylrest, z. B. eine Cyclohexenyl, 3-cyclohexenyl, 1 .3-cyclohexadienyl or 1, 4-cyclohexadienyl, wherein also substituents having a double bond on the cycloalkenyl radical, z. Legs
Alkylidengruppe wie Methyliden, umfasst sind. Im Falle von gegebenenfalls substituiertem Cycioaikenyl gelten die Erläuterungen für substituiertes Cycloalkyl entsprechend. Alkylidene group such as methylidene, are included. In the case of optionally substituted Cycioaikenyl the explanations for substituted cycloalkyl apply accordingly.
Der Begriff„Alkyliden", z. B. auch in der Form (Ci-Cio)-Alkyliden, bedeutet den Rest eines geradkettigen oder verzweigten offenkettigen Ko h I e n wa sse rstoff re sts , der über eine Zweifachbindung gebunden ist. Als Bindungsstelle für Alkyliden kommen naturgemäß nur Positionen am Grundkörper in Frage, an denen zwei H -Atome durch die Doppelbindung ersetzt werden können; Reste sind z. B. =CH-CH3, The term "alkylidene", for example also in the form (C 1 -C 10) -alkylidene, means the radical of a straight-chain or branched open-chain cohydrogen radical which is bonded via a double bond By definition, alkylidene is only possible on the basis of positions on which two H atoms can be replaced by the double bond. = CH-CH 3,
=C(CH3)-CH3, =C(CH3)-C2H5 oder =C(C2H5)-C2H5 Cycloalkyliden bedeutet ein carbocyclischer Rest, der über eine Zweifachbindung gebunden ist. Der Begriff„Stannyl" steht für einen weiter substituierten Rest, der ein Zinn-Atom enthält;„Germanyl" steht analog für einen weiter substituierten Rest, der ein = C (CH 3 ) -CH 3 , = C (CH 3 ) -C 2 H 5 or = C (C 2 H 5 ) -C 2 H 5 Cycloalkylidene means a carbocyclic radical bonded via a double bond. The term "stannyl" stands for a further substituted radical containing a tin atom, "Germanyl" is analogous to a further substituted radical which is a
Germanium-Atom enthält.„Zirconyl" steht für einen weiter substituierten Rest, der ein Zirconium-Atom enthält.„Hafnyl" steht für einen weiter substituierten Rest, der ein Hafnium-Atom enthält.„Boryl",„Borolanyl" und„Borinanyl" steht für weiter substituierte und gegebenenfalls cyclische Gruppen, die jeweils ein Bor-Atom enthalten. "Zirconyl" represents a further substituted radical containing a zirconium atom. "Hafnyl" represents a further substituted radical containing a hafnium atom. "Boryl", "Borolanyl" and "Borinanyl". stands for more substituted and optionally cyclic groups each containing a boron atom.
„Plumbanyl" steht für einen weiter substituierten Rest, der ein Blei-Atom enthält. "Plumbanyl" represents a further substituted radical containing a lead atom.
„Hydra rgyl" steht für einen weiter substituierten Rest, der ein Quecksilber-Atom enthält. „Alanyl" steht für einen weiter substituierten Rest, der ein Aluminium-Atom enthält. „Magnesyl" steht für einen weiter substituierten Rest, der ein Magnesium-Atom enthält. „Zinkyl" steht für einen weiter substituierten Rest, der ein Zink- Atom enthält. "Hydra rgyl" stands for a further substituted radical containing a mercury atom. "Alanyl" stands for a further substituted radical containing an aluminum atom. "Magnesyl" represents a further substituted radical containing a magnesium atom. "Zincyl" represents a further substituted radical containing a zinc atom.
Die Verbindungen der allgemeinen Formel (I) können je nach Art und Verknüpfung der Substituenten als Stereoisomere vorliegen. Die durch ihre spezifische Raumform definierten möglichen Stereoisomere, wie Enantiomere, Diastereomere, Z- und E- Isomere sind alle von der Formel (I) umfasst. Sind beispielsweise eine oder mehrere Alkenylgruppen vorhanden, so können Diastereomere (Z- und E-Isomere) auftreten. Sind beispielsweise ein oder mehrere asymmetrische Kohlenstoffatome vorhanden, so können Enantiomere und Diastereomere auftreten. Stereoisomere lassen sich aus den bei der Herstellung anfallenden Gemischen nach üblichen Trennmethoden erhalten. Die chromatographische Trennung kann sowohl im analytischen Maßstab zur Depending on the nature and linkage of the substituents, the compounds of the general formula (I) can exist as stereoisomers. The possible stereoisomers defined by their specific spatial form, such as enantiomers, diastereomers, Z and E isomers, are all encompassed by the formula (I). If, for example, one or more alkenyl groups are present, diastereomers (Z and E isomers) can occur. For example, if one or more asymmetric carbon atoms are present, enantiomers and diastereomers may occur. Stereoisomers can be obtained from the resulting mixtures in the preparation by conventional separation methods. The chromatographic separation can be used both on an analytical scale for
Feststellung des Enantiomerenüberschusses bzw. des Diastereomerenüberschusses, wie auch im präparativen Maßstab zur Herstellung von Prüfmustern für die biologische Ausprüfung erfolgen. Ebenso können Stereoisomere durch Einsatz stereoselektiver Reaktionen unter Verwendung optisch aktiver Ausgangs- und/oder Hilfsstoffe selektiv hergestellt werden. Die Erfindung betrifft somit auch alle Stereoisomeren, die von der allgemeinen Formel (I) umfasst, jedoch nicht mit ihrer spezifischen Stereoform angegeben sind, sowie deren Gemische Synthese: Determination of the enantiomeric excess or of the diastereomeric excess, as also carried out on a preparative scale for the production of test samples for biological testing. Similarly, stereoisomers can be selectively prepared by using stereoselective reactions using optically active sources and / or adjuvants. The invention thus also relates to all stereoisomers which comprises the general formula (I) but are not specified with their specific stereoform, and their mixtures Synthesis:
Die erfindungsgemäßen l -(Arylethinyl)-, l -(Heteroarylethinyl)-, 1 -(Heterocyclylethinyl)- und 1 -(Cyloalkenylethinyl)-bicycloalkanole der allgemeinen Formel (I) können ausgehend von bekannten Verfahren hergestellt werden (vgl. Qing et al. J. Fluorine Chem. 2000, 101 , 31 ; WO2009005794; Schmidt et al. Can. J. Chem. 1973, 51 , 3620; Zhu et al. Org. Lett. 201 1 , 13, 684; Zh. Org. Khim. 2007, 43, 679; Zh. Org. Khim. 2002, 38, 202; Compt. Rend. Acad. Sc. 267, 1968, 91 1 ; Zh. Org. Khim. 2002, 38, 1316). Einige der darin beschriebenen Verfahren zur Synthese von Vinyl- und The 1- (arylethynyl) -, 1- (heteroarylethynyl) -, 1- (heterocyclylethynyl) - and 1- (cycloalkenylethynyl) -bicycloalkanols of the general formula (I) according to the invention can be prepared starting from known processes (compare Qing et al. J. Fluorine Chem. 2000, 101, 31; WO2009005794; Schmidt et al., Can. J. Chem., 1973, 51, 3620; Zhu et al., Org. Lett. 201: 1, 13, 684; Zh. Org. Khim. 2007, 43, 679; Zh. Org. Khim. 2002, 38, 202; Compt. Rend. Acad. Sc. 267, 1968, 91 1; Zh. Org. Khim. 2002, 38, 1316). Some of the methods described therein for the synthesis of vinyl and
Alkinylbicycloalkanolgrundgerüsten wurden optimiert und durch alternative Syntheseschritte ersetzt. Die eingesetzten und untersuchten Syntheserouten gehen dabei von kommerziell erhältlichen oder leicht herstellbaren Bicycloalkanonen, Heteroaryl- und Arylhalogeniden sowie Aryl-, Heteroaryl-, Heterocyclyl- und Alkynylbicycloalkanol backbones were optimized and replaced by alternative Replaced synthesis steps. The synthetic routes used and investigated are based on commercially available or easily prepared bicycloalkanones, heteroaryl and aryl halides and also aryl, heteroaryl, heterocyclyl and
Alkenyltriflaten aus. Als ein Schlüsselintermediat für die Synthese der Alkenyl triflates. As a key intermediate for the synthesis of
erfindungsgemäßen Verbindungen der allgemeinen Formel (I) wird ein entsprechend substituiertes und Ethinylbicycloalkanol hergestellt. Dazu wird ein entsprechend substituiertes Keton entweder direkt mit einem Lithiumacetylid-Ethylendiaminkomplex in einem geeigneten polar-aproti sehen Lösungsmittel (z. B. Tetra hydrofu ran) oder in zwei Schritten durch Umsetzung mit Trimethylsilylacetylen und LDA Compounds of the general formula (I) according to the invention are prepared according to a substituted and Ethinylbicycloalkanol. For this purpose, an appropriately substituted ketone is either directly with a lithium acetylide-ethylenediamine complex in a suitable polar-aproti see solvent (eg., Tetra hydrofu ran) or in two steps by reaction with trimethylsilylacetylene and LDA
(Lithiumdiisopropylamid) in einem Temperaturbereich von -78 °C bis 0 °C in einem geeigneten polar-aproti sehen Lösungsmittel (z. B. THF = Tetra hydrofu ran) und nachfolgende Abspaltung der Trimethylsilylgruppe mit Hilfe eines geeigneten (Lithiumdiisopropylamid) in a temperature range of -78 ° C to 0 ° C in a suitable polar-aproti see solvent (eg., THF = tetrahydrofuran) and subsequent cleavage of the trimethylsilyl using a suitable
Trialkylammoniumfluorids (z. B. Tetrabutylammoniumfluorid = TBAF) in einem polar- aprotischen Lösungsmittel oder mit einer geeigneten Carbonatbase (z. B. Trialkylammonium fluoride (eg tetrabutylammonium fluoride = TBAF) in a polar aprotic solvent or with a suitable carbonate base (eg.
Kaliumcarbonat) in einem polar-proti sehen Lösungsmittel (z. B. Methanol) (vgl. J. Chem. Res. (S) 2003, 426) in das entsprechend substituierte Ethinylbicycloalkanol überführt werden (Schema 1 ). Ausgehend von den obenen beschrieben und entsprechend substituierten Ethinylcyclohexanolen können die erfindungsgemäßen substituierten 1 -(Arylethsnyl)-, l-(Heteroarylethinyl)-, l-(Heterocyclylethinyl)- und 1 - (Cyloalkenylethinyl)-bicycloalkanole (1.1 ) durch Übergangsmetall-katalysierte Kupplung mit geeigneten substituierten Aryl-, Cycloalkenyl- und Heteroarylhalogeniden oder den entsprechenden Triflaten (vgl. J. Chem. Res. (S), 2003, 426; J. Chem. Soc, Perkin Trans. 1 2001 , 47; Adv. Synth. Catal. 2005, 347, 872; Synlett 2010, 150; Org. Lett. 2008, 10, 1569; Helv. Chim. Acta 2009, 92, 826, Can. J. Chem. 1993, 71 , 983) unter Verwendung eines geeigneten Übergangsmetallkatalysatorsystems (z. B. Potassium carbonate) in a polar-protic solvent (eg methanol) (see J. Chem. Res. (S) 2003, 426) are converted into the corresponding substituted ethynylbicycloalkanol (Scheme 1). Starting from the above-described and correspondingly substituted ethynylcyclohexanols, the substituted 1- (arylethsyl) -, 1- (heteroarylethynyl) -, 1- (heterocyclylethynyl) - and 1- (cycloalkenylethynyl) -bicycloalkanols (1.1) according to the invention can be obtained by transition metal-catalyzed coupling suitable substituted aryl, cycloalkenyl and heteroaryl halides or the corresponding triflates (see J. Chem. Res. (S), 2003, 426; J. Chem. Soc, Perkin Trans. 1 2001, 47; Adv. Synth. Catal. Synlett 2010, 150; Org. Lett., 2008, 10, 1569; Helv. Chim. Acta 2009, 92, 826, Can. J. Chem., 1993, 71, 983) using a suitable transition metal catalyst system ( eg
Bis(Triphenylphosphin)palladiumdichlorid, Palladium(ll)acetat zusammen mit Bis (triphenylphosphine) palladium dichloride, palladium (II) acetate together with
Triphenylphosphin oder Bis-(Cycloacta-1 .5-dienyl)lridiumchlorid in Kombination mit einem bidentaten Liganden, z.B. 2,2'-Bis(diphenylphosphino)-1 ,1 '— binaphthyl oder 1 ,4-bis-(diphenylphosphino)butan) und eines geeigneten Kupfer(l)halogenids (z. B. Kupfer(l)iodid) in einem geeigneten Lösungsmittelgemisch aus einem Amin und einem polar aprotischen Lösungsmittel (z. B. Diisopropylamin und Toluol oder Triethylamin und Tetra hydrofu ran) hergestellt werden (Schema 1 ). R\ R2, R3, R4, R6, R7, R8, R9, R10, R11, R12 und Q haben im folgenden Schema 1 die zuvor definierten Bedeutungen. Triphenylphosphine or bis (Cycloacta-1 .5-dienyl) lridiumchlorid in combination with a bidentate ligand such as 2,2 '-bis (diphenylphosphino) -1, 1' - binaphthyl or 1, 4-bis- (diphenylphosphino) butane) and a suitable copper (I) halide (eg, copper (I) iodide) in a suitable solvent mixture of an amine and a polar aprotic solvent (eg, diisopropylamine and toluene or triethylamine and tetrahydrofuran) (Scheme 1 ). R 1 , R 3 , R 4 , R 6 , R 7 , R 8 , R 9 , R 10 , R 11 , R 12 and Q in the following Scheme 1 have the meanings defined above.
X = CI, Br, I, OTf  X = CI, Br, I, OTf
Schema 1 .  Scheme 1.
Alternativ können die erfindungsgemäßen substituierten 1 -(Arylethinyl)-, 1 - (Heteroarylethinyl)-, 1 -(Heterocyclylethinyl)- und 1 -(Cyloalkenylethinyl)-bicycloalkanole (1.1 ) durch Indiumsalz vermittelte Addition (z. B. mit lndium(lll)trifluormethansulfonat, lndium(lll)bromid, lndium(lll)chlorid, Indium(lll)iodid) eines entsprechend substituierten Aryl-, Cycloalkenyl- oder Heteroarylalkins an ein entsprechend substituiertes Keton unter Verwendung einer geeigneten Aminbase (z. B. Diisopropylamin, Triethylamin, Diisopropylethylamin, Bis-cyclohexyl(methyl)amin, N-Methylpiperidin, 1 ,8-Alternatively, the substituted 1 - (arylethynyl) -, 1- (heteroarylethynyl) -, 1 - (heterocyclylethynyl) - and 1- (cycloalkenylethynyl) -bicycloalkanols (1.1) according to the invention may be indium salt-mediated addition (eg with indium (III) trifluoromethanesulfonate, indium (III) bromide, indium (III) chloride, indium (III) iodide) of an appropriately substituted aryl, cycloalkenyl or heteroaryl alkyne to an appropriately substituted ketone using a suitable amine base (e.g., diisopropylamine, triethylamine, diisopropylethylamine , Bis-cyclohexyl (methyl) amine, N-methylpiperidine, 1, 8-
Diazabicyclo[5.4.0]undec-7-en) in einem geeigneten polar-aprotischen Lösungsmittel (z. B. Dimethoxyethan = DME, Dichlormethan = DCM, Dichlorethan, Toluol, Diazabicyclo [5.4.0] undec-7-ene) in a suitable polar aprotic solvent (eg dimethoxyethane = DME, dichloromethane = DCM, dichloroethane, toluene,
Cyclohexan) hergestellt werden (Schema 2). R1, R2, R3, R4, R6, R7, R8, R9, R10, R11, R12 und Q haben im folgenden Schema 2 die zuvor definierten Bedeutungen. Das dabei verwendete weiter substituierte Aryl-, Cycloalkenyl- oder Heteroarylalkin kann ausgehend von den entsprechenden Triflaten durch eine Palladium-Katalysator vermittelte Kupplung mit Trimethylsilylacetylen hergestellt werden (vgl. Org. Lett. 2005, 7, 1363). Cyclohexane) (Scheme 2). R 1 , R 2 , R 3 , R 4 , R 6 , R 7 , R 8 , R 9 , R 10 , R 11 , R 12 and Q in the following Scheme 2 have the meanings defined above. The further substituted aryl, cycloalkenyl or heteroarylalky used here can be prepared starting from the corresponding triflates by a palladium catalyst-mediated coupling with trimethylsilylacetylene (compare Org. Lett. 2005, 7, 1363).
Schema 2. Die erfindungsgemäßen substituierten 1 -(Arylethinyl)-, l -(Heteroarylethinyl)-, 1- (Heterocyciylethinyl)- und 1-(Cyloalkenylethinyl)-bicycloalkanole (1.1 ) können durch Folgeraktionen in die entsprechenden Analoga (I.2) bis (I.4) überführt werden. Die Hydroxygruppe der betreffenden erfindungsgemäßen substituierten Scheme 2. The substituted 1 - (arylethynyl) -, 1- (heteroarylethynyl) -, 1- (heterocyclicethynyl) - and 1- (cycloalkenylethynyl) -bicycloalkanols (1.1) according to the invention can be prepared by subsequent reactions in the corresponding analogs (I.2) to (I. 4) are transferred. The hydroxy group of the relevant substituted according to the invention
Alkinylbicycloalkanole (1.1 ) kann durch Umsetzung mit einem geeigneten  Alkynylbicycloalkanols (1.1) can be prepared by reaction with a suitable
Silyltrifluormethansulfonat-Reagenz (z. B. Triethylsilylmethansulfonat = TES-OTf) unter Verwendung einer geeigneten Base (z. B. 2,6-Lutidin) in einem geeigneten polar- aprotischen Lösungsmittel (z. B. Dichlormethan) in ein substituiertes 1 - Ethinylbicycloalkyloxy(alkyl)silan (I.2) überführt werden. Stellvertretend wird diese Umsetzung in Schema 3 unter Verwendung von Triethylsilyltrifluormethansulfonat beschrieben. Die Umsetzung eines erfindungsgemäßen substituierten Silyl trifluoromethanesulfonate reagent (eg, triethylsilyl methanesulfonate = TES-OTf) using a suitable base (e.g., 2,6-lutidine) in a suitable polar aprotic solvent (e.g., dichloromethane) to a substituted 1-ethynylbicycloalkyloxy (alkyl) silane (I.2) are transferred. By way of illustration, this reaction is described in Scheme 3 using triethylsilyl trifluoromethanesulfonate. The reaction of a substituted according to the invention
Alkinylbicycioaikanois (1.1 ) mit einem geeigneten Acylchlorid (exemplarisch in Schema 3 gezeigt durch die Reaktion mit Acetylchlorid) und einer geeigneten Aminbase (z. B. Triethylamin, Dimethylaminopyridin) in einem polar-aproti sehen Lösungsmittel (z. B. Tetra hydrofu ran oder Dichlormethan) liefert die substituierten erfindungsgemäßen Verbindungen (I.2). Alkinylbicycioaikanois (1.1) with a suitable acyl chloride (exemplified in Scheme 3 by the reaction with acetyl chloride) and a suitable amine base (eg., Triethylamine, dimethylaminopyridine) in a polar-aproti see solvent (eg., Tetra hydrofu ran or dichloromethane ) provides the substituted compounds of the invention (I.2).
Schema 3. Scheme 3.
Durch Reaktion eines erfindungsgemäßen substituierten Alkinylbicycioaikanois (1.1 ) mit einem geeigneten Gold-Katalysator (z. B. Gold(lll)bromid, Gold(lll)chlorid, By reaction of a substituted alkynylbicycioanoisine (1.1) according to the invention with a suitable gold catalyst (for example gold (III) bromide, gold (III) chloride,
Natriumtetrachloroaurat, Tetrachlorogoldsäure) und einem geeigneten nukleophilen Reaktionspartner (exemplarisch in Schema 3 gezeigt mit n-Butanol) in einem geeigneten polar-aprotischen Lösungsmittel (z. B. Tetra hydrofu ran, Dichlormethan) können die entsprechenden substituierten Alkoxythinylbicycloalkane (I.4) erhalten werden (vgl. auch J. Am. Chem. Soc. 2005, 127, 14181 ). R\ R2, R3, R4, R6, R7, R8, 9, R10, R1 1, R12 und Q haben in Schema 3 die zuvor definierten Bedeutungen. Natriumtetrachloroaurat, tetrachloroauric acid) and a suitable nucleophilic reactant (exemplified in Scheme 3 with n-butanol) in one Suitable polar aprotic solvents (eg., Tetra hydrofu ran, dichloromethane), the corresponding substituted alkoxythinylbicycloalkanes (I.4) are obtained (see also J. Am Chem, Soc., 2005, 127, 14181). R \ R 2, R 3, R 4, R 6, R 7, R 8, 9, R 10, R 1 1, R 12 and Q are as previously defined in Scheme. 3
Schema 4.  Scheme 4.
Die erfindungsgemäßen substituierten (E)-konfigurierten 1 -Arylvinyl-, 1 - Heteroarylvinyl-, 1-Cycloalkenylvinylbicycloalkanole (I.5) können durch Reduktion der Aikingruppe der entsprechenden substituierten 1 -(Arylethinyl)-, 1 -(Heteroarylethinyl)-, 1 -(Heterocyclylethinyl)- und 1 -(Cyloalkenylethinyl)-bicycloalkanole (1.1 ) unter The substituted (E) -configured 1-arylvinyl-, 1-heteroarylvinyl-, 1-cycloalkenylvinylbicycloalkanols (I.5) according to the invention can be prepared by reduction of the Aicyruppe of the corresponding substituted 1- (arylethynyl) -, 1 - (heteroarylethynyl) -, 1 - (Heterocyclylethynyl) - and 1 - (cycloalkenylethynyl) bicycloalkanols (1.1)
Verwendung geeigneter Aluminiumhydridreagenzien (z. B. Natrium-bis-(2- methoxyethoxy)-aluminiumhydrid oder Lithiumaluminiumhydrid) in einem geeigneten polar-aprotischen Lösungsmittel (z. B. Tetra hydrofu ran) (vgl. Org. Biomol. Chem.  Use of suitable aluminum hydride reagents (for example sodium bis (2-methoxyethoxy) aluminum hydride or lithium aluminum hydride) in a suitable polar aprotic solvent (for example tetrahydrofuran) (compare Org. Biomol. Chem.
2006, 4, 4186; Bioorg. Med. Chem. 2004, 12, 363-370; Tetrahedron 2003, 59, 9091 - 9100; Org. Biomol. Chem. 2006, 4, 1400-1412; Synthesis 1977, 561 ; Tetrahedron Letters 1992, 33, 3477 und Tetrahedron Letters 1974, 1593), unter Einsatz von Borhydridreagenzien (z. B. Natriumborhydrid) in einem geeigneten polar-protischen Lösungsmittel (z. B. Methanol) (vgl. Org. Lett. 2004, 6, 1785), unter Verwendung von Lithium gelöst in einem Gemisch aus Ethylamin und tert.-Butanol (z. B. Helvetica Chimica Acta 1986, 69, 368) oder unter Nutzung eines geeigneten Trialkoxysilans in Gegenwart eines geeigneten Übergangsmetallkatalysators (z. B. Tris- (acetonitril)ruthenium-l ,2,3,4.5-pentamethylcyclopentadienylhexafluorophosphat oder Tris-(acetonitril)ruthenium-cyclopentadienylhexafluorophosphat; vgl. J. Am. Chem. Soc. 2002, 124, 7622; J. Am. Chem. Soc. 2005, 127, 17645) hergestellt werden (Schema 4). Eine weitere Variante zur Reduktion der Aikingruppe stellt die Umsetzung des betreffenden Alkins mit Zink in konz. Essigsäure oder mit Zink und einem passenden Ammoniumsalz in einem geeigneten polar-aprotischen Lösungsmittel (z. B. Dichlormethan) dar (vgl. WO2006027243). In Abhängigkeit von den 2006, 4, 4186; Bioorg. Med. Chem. 2004, 12, 363-370; Tetrahedron 2003, 59, 9091 - 9100; Org. Biomol. Chem. 2006, 4, 1400-1412; Synthesis 1977, 561; Tetrahedron Letters 1992, 33, 3477 and Tetrahedron Letters 1974, 1593) using borohydride reagents (eg, sodium borohydride) in a suitable polar protic solvent (eg, methanol) (see Org. Lett., 2004, 6 , 1785), using lithium dissolved in a mixture of ethylamine and tert-butanol (eg Helvetica Chimica Acta 1986, 69, 368) or using a suitable trialkoxysilane in the presence of a suitable transition metal catalyst (eg Tris - (acetonitrile) ruthenium-1,2,3,4,5-pentamethylcyclopentadienyl hexafluorophosphate or tris (acetonitrile) ruthenium cyclopentadienyl hexafluorophosphate, see J. Am. Chem. Soc., 2002, 124, 7622; J. Am. Chem. Soc., 2005 , 127, 17645) (Scheme 4). Another variant for the reduction of the Aikingruppe represents the implementation of the respective alkyne with zinc in conc. Acetic acid or with zinc and an appropriate ammonium salt in a suitable polar aprotic solvent (e.g. Dichloromethane) (cf., WO2006027243). Depending on the
Reaktionsbedingungen können bei den Hydrierungen der Dreifachbindung als weitere Reaktionsprodukte auch die entsprechenden erfindungsgemäßen (Z)-konfigurierten Analoga erhalten werden. R\ R2, R3, R4, R5, R6, R7, R8, R9, R10, R1 1, R12 und Q haben in Schema 4 die zuvor definierten Bedeutungen. Die Reduktion von Reaction conditions can be obtained in the hydrogenation of the triple bond as further reaction products and the corresponding inventive (Z) -configured analogs. R \ R 2, R 3, R 4, R 5, R 6, R 7, R 8, R 9, R 10, R 1 1, R 12 and Q are as previously defined in Scheme. 4 The reduction of
erfindungsgemäßen substituierten 1 -(ArySethinyl)-, l-(Heteroarylethinyl)-, 1 - (Heterocyclylethinyl)- und 1-(Cyloalkenylethinyl)-bicycloalkanolen (1.1 ) zu den erfindungsgemäßen substituierten (Z)-konfigurierten 1 -Arylvinyl-, 1 -Heteroarylvinyl-, 1 - Cycloalkenylvinylbicycloalkanolen (I.6) läßt sich in Gegenwart eines  Substituted 1 - (arylsethinyl) -, 1- (heteroarylethynyl) -, 1 - (heterocyclylethynyl) - and 1- (cycloalkenylethynyl) -bicycloalkanols (1.1) according to the invention to the substituted (Z) -configured 1-arylvinyl, 1-heteroarylvinyl according to the invention -, 1 - Cycloalkenylvinylbicycloalkanolen (I.6) can be in the presence of a
Übergangsmetallkatalysators wie zum Beispiel Lindlars Katalysator mit Wasserstoff in einem geeigneten polar-apro tischen Lösungsmittel (wie z. B. n-Butanol) durchführen (vgl. Tetrahedron 1987, 43, 4107; Tetrahedron 1983, 39, 2315; J. Org. Synth. 1983, 48, 4436 und J. Am. Chem. Soc. 1984, 106, 2735) (Schema 5). R1, R2, R3, R4, R5, R6, 7, R8, R9, R10, R11, R12 und Q haben in Schema 5 die zuvor definierten Bedeutungen. Transition metal catalyst such as Lindlar's catalyst with hydrogen in a suitable polar-apro tic solvent (such as n-butanol) perform (see Tetrahedron 1987, 43, 4107, Tetrahedron 1983, 39, 2315, J. Org. 1983, 48, 4436 and J. Am. Chem. Soc., 1984, 106, 2735) (Scheme 5). R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , 7, R 8 , R 9 , R 10 , R 11 , R 12 and Q in Scheme 5 have the meanings defined above.
Schema 5.  Scheme 5.
Falls Re in den erfindungsgemäßen substituierten l -(Arylethinyl)-, 1- (Heteroarylethinyl)-, 1 -(Heterocyclylethinyl)- und 1 -(Cyloalkenylethinyl)- bicycloalkanolen (1.1 ) für eine Carboxyl- oder Formylgruppe steht, ergeben sich weitere Reaktionsmöglichkeiten. Die Carbonsäurefunktion kann mit Aminen oder Aminosäuren unter Verwendung von geeigneten Kupplungsreagenzien (z. B. 1 - Hydroxybenzotriazol = HOBt; 1 -Ethyl-3-(3-dimethylaminopropyl)carbodiimid = EDC; Dicyclohexylcarbodiimid = DCC; Benzotriazolyloxytrisfdimethylamino]-If Re in the substituted 1- (arylethinyl), 1- (heteroarylethynyl) -, 1- (heterocyclylethynyl) - and 1- (cycloalkenylethynyl) -bicycloalkanols (1.1) according to the invention represents a carboxyl or formyl group, further reaction possibilities result. The carboxylic acid function can be carried out with amines or amino acids using suitable coupling reagents (eg 1-hydroxybenzotriazole = HOBt; 1-ethyl-3- (3-dimethylaminopropyl) carbodiimide = EDC; dicyclohexylcarbodiimide = DCC; benzotriazolyloxytrifluorodimethylamino] -
10-phosphoniumhexafluorophosphat = BOP; 2-(1 H-benzotriazol-1-yL)-1 ,1 ,3,3- tetramethyluroniumhexafluorophosphat = HBTU; 2-(7-Aza-1 H-benzotriazole-1 -yl)- 1 ,1 ,3,3-tetramethyluronium hexafluorophosphat = HATU) und einer geeigneten Base (z. B. Triethylamin, Diisopropylethylamin) in einem geeigneten polar-aprotischen Lösungsmittel (z. B. Tetrahydrofuran, Dichlormethan) in ein entsprechendes erfindungsgemäßes Amid (I.7) überführt werden. Diese Umsetzung wird in Schema 6 exemplarisch am Beispiel von Glycin gezeigt. Die Formylfunktion kann mit einem gegebenenfalls weiter substituierten Hydroxylamin unter Verwendung einer geeigneten Base (z. B. Natriumacetat) in einem geeigneten polar-aprotischen Lösungsmittel (z. B. Dichlormethan, Tetrahydrofuran, Acetonitril) in entsprechendes erfindungsgemäßes Hydroxylamin (I.8) überführt werden. Diese Umsetzung wird in Schema 6 10-phosphonium hexafluorophosphate = BOP; 2- (1H-benzotriazol-1-yl) -1, 1, 3,3-tetramethyluronium hexafluorophosphate = HBTU; 2- (7-aza-1H-benzotriazole-1-yl) -1,1,3,3-tetramethyluronium hexafluorophosphate (HATU) and a suitable base (e.g., triethylamine, diisopropylethylamine) in a suitable polar aprotic Solvent (eg., Tetrahydrofuran, dichloromethane) are converted into a corresponding inventive amide (I.7). This reaction is shown in Scheme 6 using the example of glycine as an example. The formyl function can be converted with an optionally further substituted hydroxylamine using a suitable base (eg sodium acetate) in a suitable polar aprotic solvent (eg dichloromethane, tetrahydrofuran, acetonitrile) into corresponding hydroxylamine (I.8) according to the invention , This implementation is shown in Scheme 6
exemplarisch unter Verwendung von H3C-CH2-O-NH2 gezeigt. R1, R2, R3, R4, R5, R7, R8, R9, R10, R11, R12 und Q haben im folgenden Schema 6 die zuvor definierten Bedeutungen. exemplified using H3C-CH2-O-NH2. R 1 , R 2 , R 3 , R 4 , R 5 , R 7 , R 8 , R 9 , R 10 , R 11 , R 12 and Q in the following Scheme 6 have the meanings defined above.
Schema 6. Die oben beschriebenen bicyclischen Ketone können weitere Verbrückungen enthalten, so daß die in den obigen Schemata 1 bis 6 dargestellten Syntheseschritte auch auf tricyclische Ketone übertragbar sind. Beispielhaft wird dies im folgenden Schema 7 mit Hilfe der Umsetzung von Adamantanon beschrieben. R5 und Q haben im folgenden Schema 7 die zuvor definierten Bedeutungen und OH steht beispielhaft für R5. Scheme 6. The bicyclic ketones described above may contain further bridging so that the synthetic steps outlined in Schemes 1 through 6 above are also applicable to tricyclic ketones. This is described by way of example in the following Scheme 7 with the aid of the reaction of adamantanone. R 5 and Q in the following Scheme 7 have the meanings defined above and OH is exemplified by R 5 .
amine base  amine base
X = Cl, Br, I, OTf  X = Cl, Br, I, OTf
Schema 7.  Scheme 7.
Ausgewählte detaillierte Synthesebeispiele für die erfindungsgemäßen Verbindungen der allgemeinen Formel (I) sind im Folgenden aufgeführt. Die angegebenen Selected detailed synthesis examples of the compounds of the general formula (I) according to the invention are listed below. The specified
Beispielnummern entsprechen den in den nachstehenden Tabellen 1 bis XX genannten Numerierungen. Die H-NMR-, 13C-NMR- und 9F-NMR-spektroskopischen Daten, die für die in den nachfolgenden Abschnitten beschriebenen chemischen Beispiele angegeben sind, (400 MHz bei H-NMR und 150 MHz bei 13C-NMR und 375 MHz bei 9F-NMR, Lösungsmittel CDCh, CD3OD oder d6-DMSO, interner Standard: Tetramethylsilan δ = 0.00 ppm), wurden mit einem Gerät der Firma Bruker erhalten, und die bezeichneten Signale haben die nachfolgend aufgeführten Bedeutungen: br = breit(es); s = Singulett, d = Dublett, t = Triplett, dd = Doppeldublett, ddd = Dublett eines Doppeldubletts, m = Multiplett, q = Quartett, quint = Quintett, sext = Sextett, sept = Septett, dq = Doppelquartett, dt = Doppeltriplett. Bei Diastereomerengemischen werden entweder die jeweils signifikanten Signale beider Diastereomere oder das charakteristische Signal des Hauptdiastereomers angegeben. Die verwendeten Abkürzungen für chemische Gruppen haben die nachfolgenden Bedeutungen: Me = CH3, Et = CH2CH3, t-Hex = C(CH3)2CH(CH3)2, t-Bu = C(CH3)3, n-Bu = unverzweigtes Butyl, n-Pr = unverzweigtes Propyl, c-Hex = Cyclohexyl. Example numbers correspond to the numbers given in Tables 1 to XX below. The H-NMR, 13 C-NMR and 9 F-NMR spectroscopic data given for the chemical examples described in the following sections (400 MHz for H-NMR and 150 MHz for 13 C-NMR and 375 MHz at 9 F-NMR, solvent CDCh, CD 3 OD or d 6 -DMSO, internal standard: tetramethylsilane δ = 0.00 ppm), were obtained with a device from Bruker, and the signals indicated have the following meanings: br = wide (it); s = singlet, d = doublet, t = triplet, dd = double doublet, ddd = doublet of double doublet, m = multiplet, q = quartet, quint = quintet, sext = sextet, sept = septet, dq = double quartet, dt = double triplet. For diastereomeric mixtures, either the respective significant signals of both diastereomers or the characteristic signal of the main diastereomer are given. The abbreviations used have the following meanings for chemical groups: Me = CH3, Et = CH2CH3, t-Hex = C (CH 3) 2 CH (CH 3) 2, t-Bu = C (CH 3) 3, n- Bu = unbranched butyl, n-Pr = unbranched propyl, c-hex = cyclohexyl.
No. 1.1 -61 : 2-[(2-Hydroxy-1 ,3.3-trimethylbicyclo[2.2.1 ]hept-2-yl)ethinyl]benzonitril No. 1.1 -61: 2 - [(2-Hydroxy-1,3,3-trimethyl-bicyclo [2.2.1] hept-2-yl) -ethynyl] -benzonitrile
Fenchon (1500 mg, 9.85 mmol) wurde in einem Rundkolben unter Argon in abs. Fenchone (1500 mg, 9.85 mmol) was dissolved in a round bottom flask under argon in abs.
Tetra hydrofu ran (5 ml) gelöst und tropfenweise zu einer Lösung eines Lithiumacetylid- Ethylendiaminkomplexes (1474 mg, 12.81 mmol, 80% Gehalt) in abs. Tetrahydrofuran (10 ml) gegeben. Die Reaktionslösung wurde nach erfolgter Zugabe 2 h lang bei Raumtemperatur gerührt, anschließend mit Wasser versetzt und unter vermindertem Druck eingeengt. Der verbleibende Rückstand wurde mit Wasser und Dichlormethan versetzt und die wässrige Phase mehrfach mit Dichlormethan extrahiert. Die vereinigten organischen Phasen wurden über Magnesiumsulfat getrocknet, filtriert und unter vermindertem Druck eingeengt. Durch saulenchromatographische Reinigung des erhaltenen Rohproduktes (Gradient Essigester/Heptan) wurde 2-Ethinyl-1 ,3,3- trimethylbicyclo[2.2.1 ]heptan-2-ol (1400 mg, 76 % der Theorie) als farbloser wachsartiger Feststoff isoliert. Anschließend wurden Kupfer(l)iodid (6 mg, 0.03 mmol) und Bis(triphenylphosphin)palladium(ll)chlorid (18 mg, 0.3 mmol) unter Argon in einem ausgeheizten Rundkolben vorgelegt und mit abs. Toluol (2 ml) sowie 2- Cyanoiodbenzol (193 mg, 0.84 mmol) versetzt. Nach 10 Min Rühren bei Tetra hydrofu ran (5 ml) and added dropwise to a solution of a lithium acetylide-ethylenediamine complex (1474 mg, 12.81 mmol, 80% content) in abs. Tetrahydrofuran (10 ml) was added. The reaction solution was stirred for 2 h after the addition at room temperature, then treated with water and concentrated under reduced pressure. The remaining residue was mixed with water and dichloromethane and the aqueous phase extracted several times with dichloromethane. The combined organic phases were dried over magnesium sulfate, filtered and concentrated under reduced pressure. By column chromatography purification of the resulting crude product (gradient ethyl acetate / heptane) 2-ethynyl-1, 3,3-trimethylbicyclo [2.2.1] heptan-2-ol (1400 mg, 76% of theory) was isolated as a colorless waxy solid. Then copper (I) iodide (6 mg, 0.03 mmol) and bis (triphenylphosphine) palladium (II) chloride (18 mg, 0.3 mmol) were placed under argon in a heated round bottom flask and treated with abs. Toluene (2 ml) and 2-cyanoiodobenzene (193 mg, 0.84 mmol) were added. After stirring for 10 min
Raumtemperatur erfolgte die tropfenweise Zugabe einer Lösung von 2-Ethinyl-1 ,3,3- trimethylbicyclo[2.2.1 ]heptan-2-ol (150 mg, 0.84 mmol) in abs. Toluol (6 ml) und von Diisopropylamin (0.35 ml, 2.52 mmol). Das resultierende orangefarbene  Room temperature, the dropwise addition of a solution of 2-ethynyl-1, 3,3-trimethylbicyclo [2.2.1] heptan-2-ol (150 mg, 0.84 mmol) in abs. Toluene (6 mL) and diisopropylamine (0.35 mL, 2.52 mmol). The resulting orange
Reaktionsgemisch wurde 3 h lang bei Raumtemperatur gerührt und danach mit Wasser versetzt. Die wässrige Phase wurde mehrfach mit Dichlormethan extrahiert. Die vereinigten organischen Phasen wurden über Magnesiumsulfat getrocknet, filtriert und unter vermindertem Druck eingeengt. Durch abschließende The reaction mixture was stirred for 3 hours at room temperature and then treated with water. The aqueous phase was extracted several times with dichloromethane. The combined organic phases were dried over magnesium sulfate, filtered and concentrated under reduced pressure. By final
säulenchromatographische Reinigung des erhaltenen Rohproduktes (unter column chromatographic purification of the resulting crude product (under
Verwendung eines Essigester/Heptan-Gradienten) wurde 2-[(2-Hydroxy-1 ,3,3- trimethylbicyclo[2.2.1 ]hept-2-yl)ethinyl]benzonitril (108 mg, 46 % der Theorie) in Form eines schwach gelblichen Feststoffes isoliert. Ή-NMR (400 MHz, CDC δ, ppm) 7.92 (d, 1 H), 7.59 (d, 1 H), 7.45 (t, 1 H), 7.37 (t, 1 H), 2.02 (br. s, 1 H, OH), 1 .97 (m, 1 H), 1 .86 (m, 1 H), 1 .72 (m, 3H), 1 .42 (m, 1 H), 1 .21 (s. 3H), 1 .16 (s. 3H), 1 .12 (m, 1 H), 0.98 / 0.96 (s, 3H). Use of an ethyl acetate / heptane gradient) was 2 - [(2-hydroxy-1,3,3-trimethylbicyclo [2.2.1] hept-2-yl) ethynyl] benzonitrile (108 mg, 46% of theory) in the form of a isolated slightly yellowish solid. Ή-NMR (400 MHz, CDC δ, ppm) 7.92 (d, 1H), 7.59 (d, 1H), 7.45 (t, 1H), 7.37 (t, 1H), 2.02 (br. S, 1 H, OH), 1 .97 (m, 1 H), 1 .86 (m, 1 H), 1 .72 (m, 3H), 1 .42 (m, 1 H), 1 .21 (s 3H), 1 .16 (see 3H), 1 .12 (m, 1H), 0.98 / 0.96 (s, 3H).
No. 1.1 -107: 2-[(2-Hydroxy-1 ,3,3-trimethylbicyclo[2.2.1 ]hept-2-yl)ethinyl]benzoesäure No. 1.1 -107: 2 - [(2-Hydroxy-1,3,3-trimethyl-bicyclo [2.2.1] hept-2-yl) -ethynyl] benzoic acid
Fenchon (1500 mg, 9.85 mmol) wurde in einem Rundkolben unter Argon in abs. Fenchone (1500 mg, 9.85 mmol) was dissolved in a round bottom flask under argon in abs.
Tetra hydrofu ran (5 ml) gelöst und tropfenweise zu einer Lösung eines Lithiumacetylid- Ethylendiaminkomplexes (1474 mg, 12.81 mmol, 80% Gehalt) in abs. Tetrahydrofuran (10 ml) gegeben. Die Reaktionslösung wurde nach erfolgter Zugabe 2 h lang bei Raumtemperatur gerührt, anschließend mit Wasser versetzt und unter vermindertem Druck eingeengt. Der verbleibende Rückstand wurde mit Wasser und Dichlormethan versetzt und die wässrige Phase mehrfach mit Dichlormethan extrahiert. Die vereinigten organischen Phasen wurden über Magnesiumsulfat getrocknet, filtriert und unter vermindertem Druck eingeengt. Durch saulenchromatographische Reinigung des erhaltenen Rohproduktes (Gradient Essigester/Heptan) wurde 2-Ethinyl-1 ,3,3- trimethylbicyclo[2.2.1 ]heptan-2-ol (1400 mg, 76 % der Theorie) als farbloser wachsartiger Feststoff isoliert. Anschließend wurden Kupfer(l)iodid (29 mg, 0.15 mmol) und Bis(triphenylphosphin)palladium(ll)chlorid (81 mg, 0.12 mmol) unter Argon in einem ausgeheizten Rundkolben vorgelegt und mit abs. Toluol (12 ml) sowie Methyl-2- lodbenzoat (1027 mg, 3.84 mmol) versetzt. Nach 10 Min Rühren bei Raumtemperatur erfolgte die tropfenweise Zugabe einer Lösung von 1 -Ethinyl-2,2,6- trimethylcyclohexanol (685 mg, 3.84 mmol) in abs. Toluol (7 ml) und von Tetra hydrofu ran (5 ml) and added dropwise to a solution of a lithium acetylide-ethylenediamine complex (1474 mg, 12.81 mmol, 80% content) in abs. Tetrahydrofuran (10 ml) was added. The reaction solution was stirred for 2 h after the addition at room temperature, then treated with water and concentrated under reduced pressure. The remaining residue was mixed with water and dichloromethane and the aqueous phase extracted several times with dichloromethane. The combined organic phases were dried over magnesium sulfate, filtered and concentrated under reduced pressure. By column chromatography purification of the resulting crude product (gradient ethyl acetate / heptane) 2-ethynyl-1, 3,3-trimethylbicyclo [2.2.1] heptan-2-ol (1400 mg, 76% of theory) was isolated as a colorless waxy solid. Then copper (I) iodide (29 mg, 0.15 mmol) and bis (triphenylphosphine) palladium (II) chloride (81 mg, 0.12 mmol) were placed under argon in a heated round bottom flask and washed with abs. Toluene (12 ml) and methyl 2-iodobenzoate (1027 mg, 3.84 mmol) were added. After 10 min stirring at room temperature, the dropwise addition of a solution of 1-ethynyl-2,2,6-trimethylcyclohexanol (685 mg, 3.84 mmol) in abs. Toluene (7 ml) and from
Diisopropylamin (1 .62 ml, 1 1 .53 mmol). Das resultierende orangefarbene Diisopropylamine (1 .62 ml, 1 1 .53 mmol). The resulting orange
Reaktionsgemisch wurde 5 h lang bei Raumtemperatur gerührt und danach mit Wasser versetzt. Die wässrige Phase wurde mehrfach mit Dichlormethan extrahiert. Die vereinigten organischen Phasen wurden über Magnesiumsulfat getrocknet, filtriert und unter vermindertem Druck eingeengt. Durch abschließende  The reaction mixture was stirred for 5 h at room temperature and then treated with water. The aqueous phase was extracted several times with dichloromethane. The combined organic phases were dried over magnesium sulfate, filtered and concentrated under reduced pressure. By final
saulenchromatographische Reinigung des erhaltenen Rohproduktes (unter saulenchromatographic purification of the resulting crude product (under
Verwendung eines Essigester/Heptan-Gradienten) wurde Methyl-2-[(2-hydroxy-1 .3.3- trimethylbicyclo[2.2.1 ]hept-2-yl)ethinyl]benzoat (530 mg, 44 % der Theorie) in Form eines schwach gelblichen Feststoffes isoliert. Methyl-2-[(2-hydroxy-1 ,3.3- trimethylbicyclo[2.2.1 ]hept-2-yl)ethinyl]benzoat (530 mg, 1 .69 mmol) wurde in Ethanol (4 ml) gelöst und mit Wasser (25 ml) sowie fein gepulvertem Natriumhydroxid (204 mg, 5.09 mmol) versetzt. Das resultierende Reaktionsgemisch wurde 2 h lang unter Rückflußbedingungen gerührt und nach dem Abkühlen auf Raumtemperatur mit Wasser versetzt und mit verd. Salzsäure auf pH7 eingestellt. Die wässrige Phase wurde mehrfach mit Dichlormethan extrahiert. Die vereinigten organischen Phasen wurden über Magnesiumsulfat getrocknet, filtriert und unter vermindertem Druck eingeengt. Durch abschließende saulenchromatographische Reinigung des erhaltenen Rohproduktes (unter Verwendung eines Essigester/Heptan-Gradienten) wurde 2-[(2- Hydroxy-1 ,3.3-trimethylbicyclo[2.2.1 ]hept-2-yl)ethinyl]benzoesäure (460 mg, 91 % der Theorie) in Form eines farblosen Feststoffes isoliert. H-NMR (400 MHz, CDC 6, ppm) 8.08 (d, 1 H), 7.57 (d, 1 H), 7.50 (dd, 1 H), 7.40 (dd, 1 H), 2.18 (br. s, 1 H, OH), 1 .99 (m, 1 H). 1 .88 (m, 1 H), 1 .77 (m, 1 H), 1 .74 (m, 1 H), 1 .44 (m, 1 H), 1 .28 (s, 3H), 1 .24 (s, 3H), 1 .20 (m, 1 H), 1 .17 (m, 1 H), 1 .03 (s, 3H). Using an ethyl acetate / heptane gradient) was methyl 2 - [(2-hydroxy-1 .3.3-trimethylbicyclo [2.2.1] hept-2-yl) ethynyl] benzoate (530 mg, 44% of theory) in the form of a isolated slightly yellowish solid. Methyl 2 - [(2-hydroxy-1,3,3-trimethyl-bicyclo [2.2.1] hept-2-yl) -ethynyl] -benzoate (530 mg, 1.69 mmol) was dissolved in ethanol (4 ml) and washed with water ( 25 ml) and finely powdered sodium hydroxide (204 mg, 5.09 mmol). The resulting reaction mixture was allowed to stand for 2 hours Stirred reflux conditions and after cooling to room temperature with water and adjusted with dilute hydrochloric acid to pH7. The aqueous phase was extracted several times with dichloromethane. The combined organic phases were dried over magnesium sulfate, filtered and concentrated under reduced pressure. Final purification by column of the crude product obtained (using an ethyl acetate / heptane gradient) gave 2 - [(2-hydroxy-1,3,3-trimethyl-bicyclo [2.2.1] hept-2-yl) -ethynyl] benzoic acid (460 mg, 91 % of theory) in the form of a colorless solid. H-NMR (400 MHz, CDC 6, ppm) 8.08 (d, 1H), 7.57 (d, 1H), 7.50 (dd, 1H), 7.40 (dd, 1H), 2.18 (br. 1H, OH), 1 .99 (m, 1H). 1 .88 (m, 1H), 1 .77 (m, 1H), 1 .74 (m, 1H), 1 .44 (m, 1H), 1 .28 (s, 3H), 1 .24 (s, 3H), 1 .20 (m, 1H), 1 .17 (m, 1H), 1 .03 (s, 3H).
No. 1.1 -132: 2-Methoxyethyl-2-[(2-hydroxy-1 ,3,3-trimethylbicyclo[2.2.1 ]hept-2- yl)ethinyl]benzoat No. 1.1 -132: 2-Methoxyethyl 2 - [(2-hydroxy-1,3,3-trimethyl-bicyclo [2.2.1] hept-2-yl) ethynyl] benzoate
2-[(2-Hydroxy-1 ,3.3-trimethylbicyclo[2.2.1 ]hept-2-yl)ethinyl]benzoesäure (1 15 mg, 0.39 mmol), 1 -Hydroxy-1 H-benzotriazol (62 mg, 0.46 mmol) und 1 -Ethyl-3-(3- dimethylaminopropyl)carbodiimid-Hydrochlorid (89 mg, 0.46 mmol) wurden in 2 - [(2-Hydroxy-1,3,3-trimethyl-bicyclo [2.2.1] hept-2-yl) -ethynyl] -benzoic acid (15 mg, 0.39 mmol), 1-hydroxy-1H-benzotriazole (62 mg, 0.46 mmol ) and 1-ethyl-3- (3-dimethylaminopropyl) carbodiimide hydrochloride (89 mg, 0.46 mmol) were added in
Dichlormethan (6 ml) gelöst, 5 Minuten lang unter Argon gerührt und danach mit 2- Methoxyethanol (0.03 ml, 0.39 mmol) sowie Triethylamin (0.12 ml, 0.85 mmol) versetzt. Das resultierende Reaktionsgemisch wurde 3 h lang bei einer Temperatur von 50 °C gerührt und nach dem Abkühlen auf Raumtemperatur mit Wasser versetzt. Die wässrige Phase wurde mehrfach mit Dichlormethan extrahiert. Die vereinigten organischen Phasen wurden über Magnesiumsulfat getrocknet, filtriert und unter vermindertem Druck eingeengt. Durch abschließende säulenchromatographische Reinigung des erhaltenen Rohproduktes (unter Verwendung eines Essigester/Heptan- Gradienten) wurde 2-Methoxyethyl-2-[(2-hydroxy-1 ,3,3-trimethylbicyclo[2.2.1 ]hept-2- yl)ethinyl]benzoat (94 mg, 68 % der Theorie) in Form eines farblosen Feststoffes isoliert. 1H-NMR (400 MHz, CDCb 6, ppm) 7.95 (d, 1 H), 7.51 (m, 1 H), 7.44 (m, 1 H), 7.33 (m, 1 H), 4.50 (m, 2H), 3.77 (m, 2H), 3.42 (s, 3H), 3.18 (br. s, 1 H, OH), 2.04 (m, 1H), 1.86 (m, 1H), 1.78 (m, 2H), 1.43 (m, 1H), 1.24 (s, 3H), 1.21 (s, 3H), 1.18 (m, 1H), 1.13 (m, 1H), 1.02 (s, 3H). Dichloromethane (6 ml) was dissolved, stirred under argon for 5 minutes and then treated with 2-methoxyethanol (0.03 ml, 0.39 mmol) and triethylamine (0.12 ml, 0.85 mmol). The resulting reaction mixture was stirred for 3 hours at a temperature of 50 ° C and after cooling to room temperature with water. The aqueous phase was extracted several times with dichloromethane. The combined organic phases were dried over magnesium sulfate, filtered and concentrated under reduced pressure. Final purification by column chromatography of the resulting crude product (using an ethyl acetate / heptane gradient) gave 2-methoxyethyl-2 - [(2-hydroxy-1,3,3-trimethyl-bicyclo [2.2.1] hept-2-yl) -ethynyl]. Benzoate (94 mg, 68% of theory) isolated in the form of a colorless solid. 1 H-NMR (400 MHz, CDCb 6, ppm) 7.95 (d, 1H), 7.51 (m, 1H), 7.44 (m, 1H), 7.33 (m, 1H), 4.50 (m, 2H ), 3.77 (m, 2H), 3.42 (s, 3H), 3.18 (brs s, 1 H, OH), 2.04 (m, 1H), 1.86 (m, 1H), 1.78 (m, 2H), 1.43 (m, 1H), 1.24 (s, 3H), 1.21 (s, 3H), 1.18 (m, 1H), 1.13 (m, 1H ), 1.02 (s, 3H).
No.1.1-181: Methyl-N-{2-[(2-hydroxy-1 ,3,3-trimeihylbicyclo[2.2.1]hepi-2- yl)ethinyl]benzoyl}alaninat No.1.1-181: Methyl-N- {2 - [(2-hydroxy-1,3,3-trimethyl-bicyclo [2.2.1] hepi-2-yl) -ethynyl] -benzoyl-alaninate
2-[(2-Hydroxy-1.3,3-trimethylbicyclo[2.2.1]hept-2-yl)ethinyl]benzoesäure (115 mg, 0.39 mmol), 1 -Hydroxy-1 H-benzotriazol (62 mg, 0.46 mmol) und 1-Ethyl-3-(3- dimethylaminopropyl)carbodiimid-Hydrochlorid (89 mg, 0.46 mmol) wurden in 2 - [(2-Hydroxy-1,3,3-trimethyl-bicyclo [2.2.1] hept-2-yl) -ethynyl] -benzoic acid (115 mg, 0.39 mmol), 1-hydroxy-1H-benzotriazole (62 mg, 0.46 mmol) and 1-ethyl-3- (3-dimethylaminopropyl) carbodiimide hydrochloride (89 mg, 0.46 mmol) were added in
Dichlormethan (6 ml) gelöst, 5 Minuten lang unter Argon gerührt und danach mit Methylalaninat (40 mg, 0.39 mmol) sowie Triethylamin (0.12 ml, 0.85 mmol) versetzt. Das resultierende Reaktionsgemisch wurde 3 h lang bei einer Temperatur von 50 °C gerührt und nach dem Abkühlen auf Raumtemperatur mit Wasser versetzt. Die wässrige Phase wurde mehrfach mit Dichlormethan extrahiert. Die vereinigten organischen Phasen wurden über Magnesiumsulfat getrocknet, filtriert und unter vermindertem Druck eingeengt. Durch abschließende säulenchromatographische Reinigung des erhaltenen Rohproduktes (unter Verwendung eines Essigester/Heptan- Gradienten) wurde Methyl-N-{2-[(2-hydroxy-1.3.3-trimethylbicyclo[2.2.1]hept-2- yl)ethinyl]benzoyl}alaninat (105 mg, 71 % der Theorie) in Form eines farblosen Dichloromethane (6 ml) was dissolved, stirred under argon for 5 minutes and then treated with methylalaninate (40 mg, 0.39 mmol) and triethylamine (0.12 ml, 0.85 mmol). The resulting reaction mixture was stirred for 3 hours at a temperature of 50 ° C and after cooling to room temperature with water. The aqueous phase was extracted several times with dichloromethane. The combined organic phases were dried over magnesium sulfate, filtered and concentrated under reduced pressure. Final purification by column chromatography of the obtained crude product (using an ethyl acetate / heptane gradient) gave methyl N- {2 - [(2-hydroxy-1,3,3-trimethyl-bicyclo [2.2.1] -hept-2-yl) -ethynyl] -benzoyl } alaninate (105 mg, 71% of theory) in the form of a colorless
Feststoffes isoliert.1H-NMR (400 MHz, CDCh 6, ppm) 8.46 (br. m, 1H, NH), 8.15 (m, 1 H), 7.51 (m, 1 H), 7.42 (m, 2H), 4.92 (m, 1 H), 3.82 / 3.80 (s, 3H), 3.69 / 3.67 (br. s, 1 H, OH), 2.08 (m, 1 H), 1.87 (m, 1 H), 1.78 (m, 2H), 1.56 /1.53 (d, 3H), 1.48 (m, 1 H), 1.28 / 1.26 (s, 3H), 1.23/ 1.22 (s, 3H), 1.19 (m, 1H), 1.17 (m, 1H), 1.06/ 1.03 (s, 3H). Solid isolated. 1 H-NMR (400 MHz, CDCh 6, ppm) 8.46 (br, m, 1H, NH), 8.15 (m, 1H), 7.51 (m, 1H), 7.42 (m, 2H), 4.92 (m , 1H), 3.82 / 3.80 (s, 3H), 3.69 / 3.67 (brs s, 1H, OH), 2.08 (m, 1H), 1.87 (m, 1H), 1.78 (m, 2H) , 1.56 / 1.53 (d, 3H), 1.48 (m, 1H), 1.28 / 1.26 (s, 3H), 1.23 / 1.22 (s, 3H), 1.19 (m, 1H), 1.17 (m, 1H), 1.06 / 1.03 (s, 3H).
No.1.18-1: Methyl-2-[(1-ethyl-2-hydroxybicyclo[2.2.1]hept-2-yl)ethinyl]cyclohept-1-en-1- carboxylat No.1.18-1: Methyl 2 - [(1-ethyl-2-hydroxybicyclo [2.2.1] hept-2-yl) ethynyl] cyclohept-1-ene-1-carboxylate
Natriumhydrid (242 mg, 6.05 mmol, 60%ige Suspension) wurde in einem ausgeheizten Rundkolben mit abs. Diethylether (10 ml) unter Argon versetzt und nach 5 Minuten Rühren bei Raumtemperatur auf 0 °C eingekühlt. Danach erfolgte die Zugabe einer Lösung von Methylcycloheptanon-2-carboxylat (800 mg, 4.65 mmol) und nach weiteren 10 min bei 0 °C wurde Trifluormethansulfonsäureanhydrid langsam zugetropft (6.05 ml einer 1 M Lösung in Diethylether, 6.05 mmol). Das resultierende Sodium hydride (242 mg, 6.05 mmol, 60% suspension) was dissolved in a heated round bottom flask with abs. Diethyl ether (10 ml) under argon and cooled after stirring for 5 minutes at room temperature to 0 ° C. This was followed by the addition of a solution of methylcycloheptanone-2-carboxylate (800 mg, 4.65 mmol) and after a further 10 min at 0 ° C trifluoromethanesulfonic anhydride was slowly added dropwise (6.05 ml of a 1 M solution in diethyl ether, 6.05 mmol). The resulting
Reaktionsgemisch wurde 1 h lang bei 0 °C gerührt und danach mit ges. The reaction mixture was stirred for 1 h at 0 ° C and then washed with sat.
Ammoniumchloridlösung versetzt. Die wässrige Phase wurde mehrfach mit Ammonium chloride solution added. The aqueous phase was washed several times
Diethylether extrahiert. Die vereinigten organischen Phasen wurden über Extracted diethyl ether. The combined organic phases were over
Magnesiumsulfat getrocknet, filtriert und vorsichtig unter vermindertem Druck eingeengt. Durch abschließende saulenchromatographische Reinigung des erhaltenen Rohproduktes (unter Verwendung eines Essigester/Heptan-Gradienten) wurde Methyl- 2-{[(trifluormethyl)sulfonyl]oxy}cyclohept-1 -en-1 -carboxylat (900 mg, 64 % der Theorie) als farblose Flüssigkeit erhalten. 1-Ethylbicyclo[2.2.1 ]heptan-2-on (1000 mg, 7.24 mmol) wurde in einem Rundkolben unter Argon in abs. Tetra hydrofu ran (5 ml) gelöst und tropfenweise zu einer Lösung eines Lithiumacetylid-Ethylendiaminkomplexes (1962 mg, 9.41 mmol, 90% Gehalt) in abs. Tetra hydrofu ran (3 ml) gegeben. Die Reaktionslösung wurde nach erfolgter Zugabe 4 h lang bei Raumtemperatur gerührt, anschließend mit Wasser versetzt und unter vermindertem Druck eingeengt. Der verbleibende Rückstand wurde mit Wasser und Dichlormethan versetzt und die wässrige Phase mehrfach mit Dichlormethan extrahiert. Die vereinigten organischen Phasen wurden über Magnesiumsulfat getrocknet, filtriert und unter vermindertem Druck eingeengt. Durch saulenchromatographische Reinigung des erhaltenen Dried magnesium sulfate, filtered and concentrated under reduced pressure. Final purification by column of the crude product obtained (using an ethyl acetate / heptane gradient) gave methyl 2 - {[(trifluoromethyl) sulfonyl] oxy} cyclohept-1-ene-1-carboxylate (900 mg, 64% of theory) as obtained colorless liquid. 1-Ethylbicyclo [2.2.1] heptan-2-one (1000 mg, 7.24 mmol) was dissolved in a round bottom flask under argon in abs. Tetra hydrofu ran (5 ml) and added dropwise to a solution of a Lithiumacetylid-ethylenediamine complex (1962 mg, 9.41 mmol, 90% content) in abs. Tetrahydrofuran (3 ml). The reaction solution was stirred for 4 h after the addition at room temperature, then treated with water and concentrated under reduced pressure. The remaining residue was mixed with water and dichloromethane and the aqueous phase extracted several times with dichloromethane. The combined organic phases were dried over magnesium sulfate, filtered and concentrated under reduced pressure. By column chromatography purification of the obtained
Rohproduktes (Gradient Essigester/Heptan) wurde 2-Ethinyl-1 - ethylbicyclo[2.2.1 ]heptan-2-ol (700 mg, 56 % der Theorie) als farbloser wachsartiger Feststoff isoliert. Anschließend wurden Kupfer(l)iodid (19 mg, 0.09 mmol) und Crude product (gradient ethyl acetate / heptane) was isolated as a colorless waxy solid 2-ethynyl-1 - ethylbicyclo [2.2.1] heptan-2-ol (700 mg, 56% of theory). Subsequently, copper (I) iodide (19 mg, 0.09 mmol) and
Bis(triphenylphosphin)palladium(ll)chlorid (137 mg, 0.19 mmol) unter Argon in einem ausgeheizten Rundkolben vorgelegt und mit abs. Tetrahydrofuran (2 ml) sowie einer Lösung von 2-Ethinyl-1 -ethylbicyclo[2.2.1 ]heptan-2-ol (160 mg, 0.97 mmol) in abs. Tetra hydrofu ran (2 ml) und mit Diisopropylamin (0.27 ml, 1 .95 mmol) versetzt. Danach erfolgte die Zugabe einer Lösung von Methyl-2-{[(trifluormethyl)sulfonyl]oxy}cyclohept- 1 -en-1 -carboxylat (294 mg, 0.97 mmol) in abs. Tetra hydrofu ran (1 ml). Das Provided bis (triphenylphosphine) palladium (II) chloride (137 mg, 0.19 mmol) under argon in a heated round bottom flask and with abs. Tetrahydrofuran (2 ml) and a Solution of 2-ethynyl-1-ethylbicyclo [2.2.1] heptan-2-ol (160 mg, 0.97 mmol) in abs. Tetrahydrofuran (2 ml) and diisopropylamine (0.27 ml, 1 .95 mmol). This was followed by the addition of a solution of methyl 2 - {[(trifluoromethyl) sulfonyl] oxy} cyclohept-1 -ene-1-carboxylate (294 mg, 0.97 mmol) in abs. Tetra hydrofluan (1 ml). The
resultierende Reaktionsgemisch wurde 4 h lang bei Raumtemperatur gerührt und danach mit Wasser versetzt. Die wässrige Phase wurde mehrfach mit Dichlormethan extrahiert. Die vereinigten organischen Phasen wurden über Magnesiumsulfat getrocknet, filtriert und unter vermindertem Druck eingeengt. Durch abschließende säulenchromatographische Reinigung des erhaltenen Rohproduktes (unter resulting reaction mixture was stirred for 4 h at room temperature and then treated with water. The aqueous phase was extracted several times with dichloromethane. The combined organic phases were dried over magnesium sulfate, filtered and concentrated under reduced pressure. By final column chromatographic purification of the resulting crude product (under
Verwendung eines Essigester/Heptan-Gradienten) wurde Methyl-2-[(1 -ethyl-2- hydroxybicyclo[2.2.1 ]hept-2-yl)ethinyl]cyclohept-1 -en-1 -carboxylat Using an ethyl acetate / heptane gradient) became methyl 2 - [(1-ethyl-2-hydroxybicyclo [2.2.1] hept-2-yl) ethynyl] cyclohept-1-ene-1-carboxylate
(214 mg, 69 % der Theorie) in Form eines farblosen Öls isoliert. 1H-NMR (400 MHz, CDCh 6, ppm) 3.75 (s, 3H), 2.55 (m, 2H), 2.51 (m, 2H), 2.16 (m, 1 H), 1 .98 (m, 1 H), 1 .92 (br. s, 1 H, OH), 1 .77 (m, 4H), 1 .60-1 .52 (m, 7H), 1 .43 (m, 1 H), 1 .33 (m, 3H), 0.97 (t, 3H). (214 mg, 69% of theory) as a colorless oil. 1 H-NMR (400 MHz, CDCh 6, ppm) 3.75 (s, 3H), 2.55 (m, 2H), 2.51 (m, 2H), 2.16 (m, 1H), 1.98 (m, 1H ), 1 .92 (brs s, 1 H, OH), 1 .77 (m, 4H), 1 .60-1 .52 (m, 7H), 1 .43 (m, 1 H), 1. 33 (m, 3H), 0.97 (t, 3H).
No. I.25-30: Methyl-2-[(2-hydroxy-5,5,6-trimethylbicyclo[2.2.1 ]hept-2-yl)ethinyl]benzoat No. I.25-30: Methyl 2 - [(2-hydroxy-5,5,6-trimethylbicyclo [2.2.1] hept-2-yl) ethynyl] benzoate
5,5.6-Trimethylbicycloheptan-2-on (1000 mg, 6.57 mmol) wurde in einem Rundkolben unter Argon in abs. Tetra hydrofu ran (4 ml) gelöst und tropfenweise zu einer Lösung eines Lithiumacetylid-Ethylendiaminkomplexes (925 mg, 8.54 mmol, 85% Gehalt) in abs. Tetra hydrofu ran (6 ml) gegeben. Die Reaktionslösung wurde nach erfolgter Zugabe 3 h lang bei Raumtemperatur gerührt, anschließend mit Wasser versetzt und unter vermindertem Druck eingeengt. Der verbleibende Rückstand wurde mit Wasser und Dichlormethan versetzt und die wässrige Phase mehrfach mit Dichlormethan extrahiert. Die vereinigten organischen Phasen wurden über Magnesiumsulfat getrocknet, filtriert und unter vermindertem Druck eingeengt. Durch 5,5,6-Trimethylbicycloheptan-2-one (1000 mg, 6.57 mmol) was dissolved in a round bottom flask under argon in abs. Tetra hydrofu ran (4 ml) and added dropwise to a solution of a Lithiumacetylid-ethylenediamine complex (925 mg, 8.54 mmol, 85% content) in abs. Tetra hydrofu ran (6 ml). After completion of the addition, the reaction solution was stirred for 3 hours at room temperature, then treated with water and concentrated under reduced pressure. The remaining residue was mixed with water and dichloromethane and the aqueous phase extracted several times with dichloromethane. The combined organic phases were dried over magnesium sulfate, filtered and concentrated under reduced pressure. By
säulenchromatographische Reinigung des erhaltenen Rohproduktes (Gradient Essigester/Heptan) wurde 2-Ethinyl-5,5,6-trimethylbicyclo[2.2.1 ]heptan-2-ol (920 mg, 75 % der Theorie) als farbloser wachsartiger Feststoff isoliert. Anschließend wurden Kupfer(l)iodid (32 mg, 0.17 mmol) und Bis(triphenylphosphin)palladium(ll)chlorid (89 mg, 0.13 mmol) unter Argon in einem ausgeheizten Rundkolben vorgelegt und mit abs. Toluol (2 ml) sowie Methyl-2-iodbenzoat (220 mg, 0.84 mmol) versetzt. Nach 10 Min Rühren bei Raumtemperatur erfolgte die tropfenweise Zugabe einer Lösung von 2- Ethinyl-5,5,6-trimethylbicyclo[2.2.1 ]heptan-2-ol (150 mg, 0.84 mmol) in abs. Toluol (3 ml) und von Diisopropylamin (0.24 ml, 1 .68 mmol). Das resultierende orangefarbene Reaktionsgemisch wurde 2 h lang bei Raumtemperatur gerührt und danach mit Wasser versetzt. Die wässrige Phase wurde mehrfach mit Dichlormethan extrahiert. Die vereinigten organischen Phasen wurden über Magnesiumsulfat getrocknet, filtriert und unter vermindertem Druck eingeengt. Durch abschließende column-chromatographic purification of the crude product obtained (gradient Ethyl acetate / heptane), 2-ethynyl-5,5,6-trimethyl-bicyclo [2.2.1] heptan-2-ol (920 mg, 75% of theory) was isolated as a colorless waxy solid. Then copper (I) iodide (32 mg, 0.17 mmol) and bis (triphenylphosphine) palladium (II) chloride (89 mg, 0.13 mmol) were placed under argon in a heated round bottom flask and washed with abs. Toluene (2 ml) and methyl 2-iodobenzoate (220 mg, 0.84 mmol) were added. After 10 min stirring at room temperature, the dropwise addition of a solution of 2-ethynyl-5,5,6-trimethylbicyclo [2.2.1] heptan-2-ol (150 mg, 0.84 mmol) in abs. Toluene (3 mL) and diisopropylamine (0.24 mL, 1.68 mmol). The resulting orange reaction mixture was stirred for 2 h at room temperature and then water was added. The aqueous phase was extracted several times with dichloromethane. The combined organic phases were dried over magnesium sulfate, filtered and concentrated under reduced pressure. By final
säulenchromatographische Reinigung des erhaltenen Rohproduktes (unter column chromatographic purification of the resulting crude product (under
Verwendung eines Essigester/Heptan-Gradienten) wurde Methyl-2-[(2-hydroxy-5,5,6- trimethylbicyclo[2.2.1 ]hept-2-yl)ethinyl]benzoat (60 mg, 22 % der Theorie) in Form eines farblosen Feststoffes isoliert. Ή-NMR (400 MHz, CDCh δ, ppm) 7.91 (d, 1 H), 7.50 (d, 1 H), 7.43 (dd, 1 H), 7.34 (dd, 1 H), 3.91 (s, 3H), 2.08-2.02 (m, 2 H), 1 .98 (br. s, 1 H, OH), 1 .92 (m, 1 H), 1 .88 (m, 2H), 1 .76 (m, 1 H), 1 .69 (m, 1 H), 1 .08 / 1 .02 (s, 3H), 0.92 / 0.90 (s, 3H), 0.88 / 0.86 (d, 3H). Using an ethyl acetate / heptane gradient) was methyl 2 - [(2-hydroxy-5,5,6-trimethylbicyclo [2.2.1] hept-2-yl) ethynyl] benzoate (60 mg, 22% of theory) in Isolated form of a colorless solid. Ή-NMR (400 MHz, CDCh δ, ppm) 7.91 (d, 1H), 7.50 (d, 1H), 7.43 (dd, 1H), 7.34 (dd, 1H), 3.91 (s, 3H) , 2.08-2.02 (m, 2H), 1 .98 (br s, 1H, OH), 1 .92 (m, 1H), 1 .88 (m, 2H), 1 .76 (m, 1H), 1 .69 (m, 1H), 1 .08 / 1 .02 (s, 3H), 0.92 / 0.90 (s, 3H), 0.88 / 0.86 (d, 3H).
No. I.27-30: Methyl-2-[(2-hydroxy-3-methylenbicyclo[2.2.1 ]hept-2-yl)ethinyl]benzoat No. I.27-30: Methyl 2 - [(2-hydroxy-3-methylenebicyclo [2.2.1] hept-2-yl) ethynyl] benzoate
3-Methylen-2-Norbornanon (1000 mg, 8.19 mmol) wurde in einem Rundkolben unter Argon in abs. Tetrahydrofuran (2 ml) gelöst und tropfenweise zu einer Lösung eines Lithiumacetylid-Ethylendiaminkomplexes (1 153 mg, 10.64 mmol, 85% Gehalt) in abs. Tetrahydrofuran (4 ml) gegeben. Die Reaktionslösung wurde nach erfolgter Zugabe 3 h lang bei Raumtemperatur gerührt, anschließend mit Wasser versetzt und unter vermindertem Druck eingeengt. Der verbleibende Rückstand wurde mit Wasser und Dichlormethan versetzt und die wässrige Phase mehrfach mit Dichlormethan extrahiert. Die vereinigten organischen Phasen wurden über Magnesiumsulfat getrocknet, filtriert und unter vermindertem Druck eingeengt. Durch 3-Methylene-2-norbornanone (1000 mg, 8.19 mmol) was dissolved in a round bottom flask under argon in abs. Tetrahydrofuran (2 ml) was dissolved and added dropwise to a solution of a Lithiumacetylid-ethylenediamine complex (1 153 mg, 10.64 mmol, 85% content) in abs. Tetrahydrofuran (4 ml). After completion of the addition, the reaction solution was stirred for 3 hours at room temperature, then treated with water and concentrated under reduced pressure. The remaining residue was mixed with water and dichloromethane and the aqueous phase repeatedly with dichloromethane extracted. The combined organic phases were dried over magnesium sulfate, filtered and concentrated under reduced pressure. By
säulenchromatographische Reinigung des erhaltenen Rohproduktes (Gradient column-chromatographic purification of the crude product obtained (gradient
Essigester/Heptan) wurde 2-Ethinyl-3-methylenbicyclo[2.2.1 ]heptan-2-ol (510 mg, 40 % der Theorie) als farbloser wachsartiger Feststoff isoliert. Anschließend wurden Kupfer(l)iodid (39 mg, 0.20 mmol) und Bis(triphenylphosphin)palladium(ll)chlorid (107 mg, 0.15 mmol) unter Argon in einem ausgeheizten Rundkolben vorgelegt und mit abs. Toluol (2 ml) sowie Methyl-2-iodbenzoat (265 mg, 1 .01 mmol) versetzt. Nach 10 Min Rühren bei Raumtemperatur erfolgte die tropfenweise Zugabe einer Lösung von 2- Ethinyl-3-methylenbicyclo[2.2.1 ]heptan-2-ol (150 mg, 1 .01 mmol) in abs. Toluol (3 ml) und von Diisopropylamin (0.28 ml, 2.02 mmol). Das resultierende orangefarbene Reaktionsgemisch wurde 2 h lang bei Raumtemperatur gerührt und danach mit Wasser versetzt. Die wässrige Phase wurde mehrfach mit Dichlormethan extrahiert. Die vereinigten organischen Phasen wurden über Magnesiumsulfat getrocknet, filtriert und unter vermindertem Druck eingeengt. Durch abschließende Ethyl acetate / heptane), 2-ethynyl-3-methylenebicyclo [2.2.1] heptan-2-ol (510 mg, 40% of theory) was isolated as a colorless waxy solid. Then copper (I) iodide (39 mg, 0.20 mmol) and bis (triphenylphosphine) palladium (II) chloride (107 mg, 0.15 mmol) were placed under argon in a heated round bottom flask and washed with abs. Toluene (2 ml) and methyl 2-iodobenzoate (265 mg, 1 .01 mmol) were added. After 10 min stirring at room temperature, the dropwise addition of a solution of 2-ethynyl-3-methylenbicyclo [2.2.1] heptan-2-ol (150 mg, 1 .01 mmol) in abs. Toluene (3 ml) and diisopropylamine (0.28 ml, 2.02 mmol). The resulting orange reaction mixture was stirred for 2 h at room temperature and then water was added. The aqueous phase was extracted several times with dichloromethane. The combined organic phases were dried over magnesium sulfate, filtered and concentrated under reduced pressure. By final
säulenchromatographische Reinigung des erhaltenen Rohproduktes (unter column chromatographic purification of the resulting crude product (under
Verwendung eines Essigester/Heptan-Gradienten) wurde Methyl-2-[(2-hydroxy-3- methylenbicyclo[2.2.1 ]hept-2-yl)ethinyl]benzoat (100 mg, 33 % der Theorie) in Form eines farblosen Feststoffes isoliert. H-NMR (400 MHz, CDCb δ, ppm) 7.93 (d, 1 H), 7.51 (d, 1 H), 7.44 (dd, 1 H), 7.35 (dd, 1 H), 5.22 / 5.12 (s, 1 H), 5.05 / 5.01 (s, 1 H), 3.92 (s, 3H), 2.86 / 2.79 (m, 1 H), 2.65 / 2.53 (m, 1 H), 2.17 (br. s, 1 H, OH), 2.02 (m, 1 H), 1 .98 (m, 1 H), 1 .84 (m, 1 H), 1 .77-1 .68 (m, 1 H), 1 .52 (m, 1 H), 1 .43 (m, 1 H). Using an ethyl acetate / heptane gradient) was added methyl 2 - [(2-hydroxy-3-methylenebicyclo [2.2.1] hept-2-yl) ethynyl] benzoate (100 mg, 33% of theory) as a colorless solid isolated. H-NMR (400 MHz, CDCb δ, ppm) 7.93 (d, 1H), 7.51 (d, 1H), 7.44 (dd, 1H), 7.35 (dd, 1H), 5.22 / 5.12 (s, 1 H), 5.05 / 5.01 (s, 1H), 3.92 (s, 3H), 2.86 / 2.79 (m, 1H), 2.65 / 2.53 (m, 1H), 2.17 (brs s, 1 H, OH), 2.02 (m, 1H), 1 .98 (m, 1H), 1 .84 (m, 1H), 1 .77-1 .68 (m, 1H), 1 .52 (m , 1 H), 1 .43 (m, 1 H).
In Analogie zu oben angeführten und in den nachstehenden Tabellen rezitierten Herstellungsbeispielen und unter Berücksichtigung der allgemeinen Angaben zur Herstellung von substituierten 1 -(Ar lethinyl)-, 1 -(Heteroarylethinyl)-, 1 - (Heterocyclylethinyl)- und 1-(Cyloalkenylethinyl)-bicycloalkanolen sowie deren Analoga der allgemeinen Formel (I) erhält man folgende in den Tabellen 1 bis 37 spezifisch genannten Verbindungen: Tabelle 1:By analogy with the preparation examples cited above and recited in the tables below, and taking into account the general information on the preparation of substituted 1 - (arethethinyl) -, 1 - (heteroarylethynyl) -, 1 - (heterocyclylethynyl) - and 1- (cycloalkenylethynyl) - bicycloalkanols and their analogs of general formula (I), the following are given in Table 1 to 37 specifically mentioned compounds: Table 1:
No. R5 R6 R13 R4 R5 R16 No. R 5 R 6 R 13 R 4 R 5 R 16
1.1-101 OH C2F5 H H H H1.1-101 OH C 2 F 5 HHHH
1.1-102 OH CHF2 H H H H 1.1-102 OH CHF 2 HHHH
1.1-103 OH H H H H 1.1-103 OH H H H H
OH  OH
1.1-104 OH H H H H1.1-104 OH H H H H
! !
/°  / °
1.1-105 OH H H H H 1.1-105 OH H H H H
I  I
\^,0  \ ^ 0
1.1-106 OH H H H H 1.1-106 OH H H H H
1.1-107 OH X H H H H 1.1-107 OH X H H H H
OH  OH
1.1-108 OH X F H H H 1.1-108 OH X F H H H
OH  OH
1.1-109 OH H H1.1-109 OH H H
C X H F T OH C X H F T OH
1.1-110 OH X H H F H 1.1-110 OH X H H F H
OH i.1-111 OH X H H H F  OH i.1-111 OH X H H H F
OH  OH
1.1-112 OH X CH3 H H H er OH 1.1-112 OH X CH 3 HHH he OH
1.1-113 OH H CH3 H H 1.1-113 OH H CH 3 HH
O^OH i.1-114 OH H H CH3 HO ^ OH i.1-114 OH HH CH 3 H
CT X OH CT X OH
1.1-115 OH H H H CH3 1.1-115 OH HHH CH 3
O X"^ OH No. R5 R6 R13 R4 R5 R16 OX "^ OH No. R 5 R 6 R 13 R 4 R 5 R 16
1.1-131 OH H H H H 1.1-131 OH H H H H
1.1-132 OH H H H H 1.1-132 OH H H H H
er o ^  he o ^
1.1-133 OH H H H H 1.1-133 OH H H H H
1.1-134 OH H H H H 1.1-134 OH H H H H
er o i.1-135 OH H H H H  he o i.1-135 OH H H H H
1.1-136 OH H H H H 1.1-136 OH H H H H
1.1-137 OH H H H H 1.1-137 OH H H H H
1.1-138 OH H H H H 1.1-138 OH H H H H
1.1-139 OH H H H H 1.1-139 OH H H H H
1.1-140 OH H H H H 1.1-140 OH H H H H
1.1-141 OH H H H H 1.1-141 OH H H H H
1.1-142 OH H H H H 1.1-142 OH H H H H
F  F
1.1-143 OH F H H H cr^o-" 1.1-143 OH F H H H cr ^ o- "
1.1-144 OH Cl H H H No. R5 R6 R13 R14 R15 R16 1.1-144 OH Cl HHH No. R 5 R 6 R 13 R 14 R 15 R 16
1.1-159 OH H H H H 1.1-159 OH H H H H
1.1-160 OH H H H H1.1-160 OH H H H H
H H
1.1-161 OH H H H H 1.1-161 OH H H H H
1.1-162 OH H H H H 1.1-162 OH H H H H
1.1-163 OH H H H H 1.1-163 OH H H H H
1.1-164 OH H H H H1.1-164 OH H H H H
H H
1.1-165 OH H H H H 1.1-165 OH H H H H
I  I
1.1-166 OH H H H H 1.1-166 OH H H H H
1.1-167 OH H H H H 1.1-167 OH H H H H
1.1-168 OH O N \ H H H H H 1.1-168 OH O N HH H H
1.1-169 OH H H H H1.1-169 OH H H H H
0 0
1.1-170 OH H H H H1.1-170 OH H H H H
' 0 No. R5 R6 R13 R4 R5 R16 '0 No. R 5 R 6 R 13 R 4 R 5 R 16
1.1-209 OnPr H H H H 1.1-209 O n Pr HHHH
1.1-210 OnPr H H CH3 H 1.1-210 O n Pr HH CH 3 H
1.1-211 0"Pr H H H CH3 1.1-211 0 "Pr HHH CH 3
1.1-212 OnBu F H H H H1.1-212 O n Bu FHHHH
1.1-213 OnBu CH3 H H H H1.1-213 O n Bu CH 3 HHHH
1.1-214 OnBu OCH3 H H H H 1.1-214 O n Bu OCH 3 HHHH
1.1-215 OnBu H H H H 1.1-215 O n Bu HHHH
1.1-216 OnBu H H CH3 H 1.1-216 O n Bu HH CH 3 H
1.1-217 OnBu H H H CH3 1.1-217 O n Bu HHH CH 3
1.1-224 OSi(Et)3 F H H H H1.1-224 OSi (Et) 3 FHHHH
1.1-225 OSi(Et)3 CH3 H H H H1.1-225 OSi (Et) 3 CH 3 HHHH
1.1-226 OSi(Et)3 OCH3 H H H H 1.1-226 OSi (Et) 3 OCH3 HHHH
1.1-227 OSi(Et)3 H H H H 1.1-227 OSi (Et) 3 HHHH
1.1-228 OSi(Et)3 H H CH3 H 1.1-228 OSi (Et) 3 HH CH 3 H
1.1-229 OSi(Et)3 H H H CH3 1.1-229 OSi (Et) 3 3 HHH CH
1.1-230 OSiMe2t-Bu F H H H H1.1-230 OSiMe 2 t-Bu FHHHH
1.1-231 OSiMe2t-Bu CH3 H H H H1.1-231 OSiMe 2 t-Bu CH 3 HHHH
1.1-232 OSiMe2t-Bu OCH3 H H H H 1.1-232 OSiMe 2 t-Bu OCH3 HHHH
1.1-233 OSiMe2t-Bu H H H H 1.1-233 OSiMe 2 t-Bu HHHH
1.1-234 OSi e2t-Bu H H CH3 H 1.1-234 OSi e 2 t-Bu HH CH 3 H
Tabelle 2: Table 2:
No. R5 R6 A5 R 7 R18 No. R 5 R 6 A 5 R 7 R 18
I.3-23 OSi(Et)3 S H H I.3-23 OSi (Et) 3 SHH
I.3-24 OSiMe2t-Bu S H H I.3-24 OSiMe 2 t-Bu SHH
I.3-25 OAc s H H I.3-25 OAc s H H
Tabelle 4: Table 4:
No. R5 R6 A6 A7 R19 R20 R23 R24 No. R 5 R 6 A 6 A 7 R 19 R 20 R 23 R 24
1.4-1 OH CH2 CH2 H H H H 1.4-1 OH CH 2 CH 2 HHHH
I.4-2 OH CH2 CH2 H H H H I.4-2 OH CH 2 CH 2 HHHH
I.4-3 OH CH2 0 H H H H I.4-3 OH CH 2 0 HHHH
I.4-4 OH CH2 0 H H H H I.4-4 OH CH 2 0 HHHH
I.4-5 OH CH2 s H H H H I.4-5 OH CH 2 s HHHH
I.4-6 OH CH2 s H H H H I.4-6 OH CH 2 s HHHH
I.4-7 OH CH2 H H H H I.4-7 OH CH 2 HHHH
Tabelle 5:Table 5:
No. R5 R6 A8 R25 R26 R28 R29 No. R 5 R 6 A 8 R 25 R 26 R 28 R 29
1.5-13 OAc CH2 H H H H 1.5-13 OAc CH 2 HHHH
1.5-14 OAc CH2 H H H H 1.5-14 OAc CH 2 HHHH
1.5-15 OSiEt3 CH2 H H H H 1.5-15 OSiEt 3 CH 2 HHHH
1.5-16 OSiEt3 CH2 H H H H 1.5-16 OSiEt 3 CH 2 HHHH
Tabelle 6: Table 6:
No. R5 R6 A9 R31 R32 R34 R35No. R 5 R 6 A 9 R 31 R 32 R 34 R 35
1.6-1 OH CH2 H H H H 1.6-1 OH CH 2 HHHH
I.6-2 OH CH2 H H H H I.6-2 OH CH 2 HHHH
I.6-3 OH 0 H H H H I.6-3 OH 0 H H H H
I.6-4 OH 0 H H H H I.6-4 OH 0 H H H H
I.6-5 OH s H H H H I.6-5 OH s H H H H
I.6-6 OH s H H H H No. R5 R6 A9 R3 R32 R34 R35 I.6-6 OH s HHHH No. R 5 R 6 R 9 A 3 R32 R34 R 35
I.6-7 OH I.6-7 OH
o^o^ -X- H H H H  o ^ o ^ -X- H H H H
I.6-8 OH ■· · H H H H I.6-8 OH ■ · · HHHH
I.6-9 OH CH2 H H H HI.6-9 OH CH 2 HHHH
0 X^ OH .6-10 OH CH2 H H H H .6-1 1 OH CH2 H H H H .6-12 OH CH2 H H H H .6-13 OAc CH2 H H H H .6-14 OAc CH2 H H H H o^o^ .6-15 OSiEt;, CH2 H H H H .6-16 OSiEt3 CH2 H H H H o^o^ 0 X ^ OH .6-10 OH CH 2 HHHH .6-1 1 OH CH 2 HHHH .6-12 OH CH 2 HHHH .6-13 OAc CH 2 HHHH .6-14 OAc CH 2 HHHH o ^ o ^. 6-15 OSiEt ;, CH 2 HHHH .6-16 OSiEt 3 CH 2 HHHH o ^ o ^
Tabelle 7:Table 7:
No. R5 R6 R13 R4 R5 R16 No. R 5 R 6 R 13 R 4 R 5 R 16
1.7-116 OH H H H H 1.7-116 OH H H H H
1.7-117 OH F H H H 1.7-117 OH F H H H
1.7-118 OH H F H H 1.7-118 OH H F H H
1.7-119 OH H H F H 1.7-119 OH H H F H
1.7-120 OH H H H F 1.7-120 OH H H H F
1.7-121 OH CH3 H H H 1.7-121 OH CH 3 HHH
1.7-122 OH H CH3 H H 1.7-122 OH H CH 3 HH
1.7-123 OH H H CH3 H 1.7-123 OH HH CH 3 H
1.7-124 OH H H H CH3 1.7-124 OH HHH CH 3
1.7-125 OH H H H H 1.7-125 OH H H H H
1.7-126 OH H H H H 1.7-126 OH H H H H
1.7-127 OH H H H H 1.7-127 OH H H H H
CT 0 Ph  CT 0 Ph
1.7-128 OH H H H H 1.7-128 OH H H H H
1.7-129 OH H H H H 1.7-129 OH H H H H
1.7-130 OH H H H H No. R5 R6 R13 R 4 R 5 R16 1.7-130 OH HHHH No. R 5 R 6 R 13 R 4 R 5 R 16
1.7-131 OH H H H H1.7-131 OH H H H H
1.7-132 OH H H H H 1.7-132 OH H H H H
er o ^  he o ^
1.7-133 OH H H H H1.7-133 OH H H H H
1.7-134 OH H H H H1.7-134 OH H H H H
CT O \/ \^ CT O \ / \ ^
1.7-1 35 OH H H H H 1.7-1 35 OH H H H H
1.7-136 OH H H H H 1.7-136 OH H H H H
1.7-137 OH H H H H 1.7-137 OH H H H H
1.7-138 OH H H H H 1.7-138 OH H H H H
1.7-139 OH H H H H1.7-139 OH H H H H
1.7-140 OH H H H H1.7-140 OH H H H H
1.7-141 OH H H H H 1.7-141 OH H H H H
1.7-142 OH H H H H 1.7-142 OH H H H H
F  F
1.7-143 OH F H H H1.7-143 OH F H H H
1.7-144 OH Cl H H H No. R5 R6 R13 R 4 R 5 R16 1.7-144 OH Cl HHH No. R 5 R 6 R 13 R 4 R 5 R 16
1.7-159 OH H H H H 1.7-159 OH H H H H
1.7-160 OH H H H H 1.7-160 OH H H H H
H  H
1.7-161 OH H H H H 1.7-161 OH H H H H
1.7-162 OH H H H H 1.7-162 OH H H H H
H ^  H ^
1.7-163 OH H H H H 1.7-163 OH H H H H
1.7-164 OH H H H H 1.7-164 OH H H H H
H  H
1.7-165 OH H H H H 1.7-165 OH H H H H
I  I
1.7-166 OH H H H H 1.7-166 OH H H H H
1.7-167 OH H H H H 1.7-167 OH H H H H
1.7-168 OH /\ /O. 1.7-168 OH / \ / O.
0 N \ H H H H 0 N \ H H H H
H H
1.7-169 OH H H H H 1.7-169 OH H H H H
0  0
1.7-170 OH H H H H 1.7-170 OH H H H H
' 0 No. R5 R6 R13 R 4 R 5 R16 '0 No. R 5 R 6 R 13 R 4 R 5 R 16
I.7-209 OnPr H H H H I.7-209 O n Pr HHHH
1.7-210 OnPr H H CH3 H 1.7-210 O n Pr HH CH 3 H
1.7-21 1 0"Pr H H H CH3 1.7-21 1 0 "Pr HHH CH 3
1.7-212 OnBu F H H H H1.7-212 O n Bu FHHHH
1.7-213 OnBu CH3 H H H H1.7-213 O n Bu CH 3 HHHH
1.7-214 OnBu OCH3 H H H H 1.7-214 O n Bu OCH 3 HHHH
1.7-215 OnBu H H H H 1.7-215 O n Bu HHHH
1.7-216 OnBu H H CH3 H 1.7-216 O n Bu HH CH 3 H
1.7-217 OnBu H H H CH3 1.7-217 O n Bu HHH CH 3
I.7-224 OSi(Et)3 F H H H HI.7-224 OSi (Et) 3 FHHHH
I.7-225 OSi(Et)3 CH3 H H H HI.7-225 OSi (Et) 3 CH 3 HHHH
I.7-226 OSi(Et)3 OCH3 H H H H I.7-226 OSi (Et) 3 OCH3 HHHH
I.7-227 OSi(Et)3 H H H H I.7-227 OSi (Et) 3 HHHH
I.7-228 OSi(Et)3 H H CH3 H I.7-228 OSi (Et) 3 CH3 H HH
I.7-229 OSi(Et)3 H H H CH3 I.7-229 OSi (Et) 3 3 HHH CH
I.7-230 OSiMe2t-Bu F H H H HI.7-230 OSiMe 2 t-Bu FHHHH
1.7-231 OSiMe2t-Bu CH3 H H H H1.7-231 OSiMe 2 t-Bu CH 3 HHHH
I.7-232 OSiMe2t-Bu OCH3 H H H H I.7-232 OSiMe 2 t-Bu OCH3 HHHH
I.7-233 OSiMe2t-Bu H H H H I.7-233 OSiMe 2 t-Bu HHHH
I.7-234 OSiMe2t-Bu H H CH3 H I.7-234 OSiMe 2 t-Bu HH CH 3 H
No. R5 R6 A1 A2 A3 A4 No. R 5 R 6 A 1 A 2 A 3 A 4
1.8-1 OH F N C-H C-H C-H1.8-1 OH F N C-H C-H C-H
I.8-2 OH Cl N C-H C-H C-HI.8-2 OH Cl N C-H C-H C-H
I.8-3 OH Br N C-H C-H C-HI.8-3 OH Br N C-H C-H C-H
I.8-4 OH I N C-H C-H C-HI.8-4 OH I N C-H C-H C-H
I.8-5 OH CH3 N C-H C-H C-HI.8-5 OH CH 3 N CH CH CH
I.8-6 OH OCH3 N C-H C-H C-HI.8-6 OH OCH3 N C-H C-H C-H
I.8-7 OH SCH3 N C-H C-H C-H I.8-7 OH SCH 3 CH CH CH
No. R5 R6 A5 R 7 R18 No. R 5 R 6 A 5 R 7 R 18
I.9-8 OH S H H I.9-8 OH S H H
I  I
I.9-9 OH S CH3 H I.9-9 OH S CH 3 H
1.9-10 OH s CH3 CH3 1.9-10 OH s CH 3 CH 3
1.9-1 1 OH s H CH3 1.9-1 1 OH s H CH 3
1.9-12 OH 0 H H 1.9-12 OH 0 H H
1.9-13 OH 0 H H 1.9-13 OH 0 H H
1.9-14 OH 0 CH3 H 1.9-14 OH 0 CH 3 H
1.9-15 OH 0 H CH3 1.9-15 OH 0 H CH 3
1.9-16 OH 0 H H 1.9-16 OH 0 H H
0 X^ OH  0 X ^ OH
1.9-17 OH X s H H 1.9-17 OH X s H H
OH  OH
1.9-18 OH 1.9-18 OH
0 X N-CH3 H H ^ OH 0 X N-CH 3 HH ^ OH
1.9-19 OH N-CH3 H H o^o-" 1.9-19 OH N-CH 3 HH o ^ o- "
I.9-20 OH N-CH3 H H I.9-20 OH N-CH3 HH
O^o"^  O ^ o '^
1.9-21 OH N-CH3 CH3 H ο^ο-" 1.9-21 OH N-CH3 CH3 H ο ^ ο- "
I.9-22 OH N-CH3 H CH3 I.9-22 OH N-CH3 H CH3
0^0^ No. R5 R6 A5 R 7 R18 0 ^ 0 ^ No. R 5 R 6 A 5 R 7 R 18
I.9-23 OSi(Et)3 S H H I.9-23 OSi (Et) 3 SHH
I.9-24 OSiMe2t-Bu 0J 0/ s H H I.9-24 OSiMe 2 t-Bu 0 J 0 / s HH
I.9-25 OAc s H H I.9-25 OAc s H H
Tabelle 10: Table 10:
No. R5 R6 A6 A7 R19 R20 R23 R24 No. R 5 R 6 A 6 A 7 R 19 R 20 R 23 R 24
1.10-1 OH CH2 CH2 H H H H 1.10-1 OH CH 2 CH 2 HHHH
1.10-2 OH CH2 CH2 H H H H 1.10-2 OH CH 2 CH 2 HHHH
1.10-3 OH CH2 0 H H H H 1.10-3 OH CH 2 0 HHHH
1.10-4 OH CH2 0 H H H H 1.10-4 OH CH 2 0 HHHH
1.10-5 OH CH2 s H H H H 1.10-5 OH CH 2 s HHHH
1.10-6 OH CH2 s H H H H 1.10-6 OH CH 2 s HHHH
1.10-7 OH CH2 •· · H H H H 1.10-7 OH CH 2 • · · HHHH
Tabelle 11:Table 11:
Tabelle 12: Table 12:
No. R5 R6 Α9 R25 R26 R28 R29 No. R 5 R 6 Α 9 R 25 R 26 R 28 R 29
1.12-7 OH 1.12-7 OH
o^o^ -X- H H H H  o ^ o ^ -X- H H H H
1.12-8 OH ■· · H H H H 1.12-8 OH ■ · · HHHH
1.12-9 OH CH2 H H H H1.12-9 OH CH 2 HHHH
0 X^ OH 0 X ^ OH
1.12-10 OH CH2 H H H H 1.12-10 OH CH 2 HHHH
1.12-1 1 OH CH2 H H H H ο^ο^ 1.12-1 1 OH CH 2 HHHH ο ^ ο ^
1.12-12 OH CH2 H H H H 1.12-12 OH CH 2 HHHH
1.12-13 OAc CH2 H H H H ο^ο^ 1.12-13 OAc CH 2 HHHH ο ^ ο ^
1.12-14 OAc CH2 H H H H ο^ο^ 1.12-14 OAc CH 2 HHHH ο ^ ο ^
1.12-15 OSiEis CH2 H H H H ο^ο^ 1.12-15 OSiEis CH 2 HHHH ο ^ ο ^
1.12-16 OSiEt3 CH2 H H H H 1.12-16 OSiEt 3 CH 2 HHHH
Tabelle 13:Table 13:
No. R5 R6 R13 R4 R15 R16 No. R 5 R 6 R 13 R 4 R 15 R 16
1.13-101 OH C2F5 H H H H1.13-101 OH C 2 F 5 HHHH
1.13-102 OH CHF2 H H H H 1.13-102 OH CHF 2 HHHH
1.13-103 OH H H H H 1.13-103 OH H H H H
OH  OH
1.13-104 OH H H H H 1.13-104 OH H H H H
I  I
/°  / °
1.13-105 OH H H H H 1.13-105 OH H H H H
I  I
1.13-106 OH H H H H 1.13-106 OH H H H H
1.13-107 OH X H H H H 1.13-107 OH X H H H H
OH  OH
1.13-108 OH X F H H H 1.13-108 OH X F H H H
0^ OH  0 ^ OH
1.13-109 OH X H F H H 1.13-109 OH X H F H H
OH  OH
1.13-110 OH X H H F H 1.13-110 OH X H H F H
OH  OH
1.13-111 OH X H H H F 1.13-111 OH X H H H F
OH  OH
1.13-112 OH CH3 H H H o X^ OH 1.13-112 OH CH 3 HHH o X ^ OH
1.13-113 OH H CH3 H H 1.13-113 OH H CH 3 HH
O^OH  O ^ OH
1.13-114 OH H H CH3 H 1.13-114 OH HH CH 3 H
O X"^ OH  O X "^ OH
1.13-115 OH X H H H CH3 1.13-115 OH XHHH CH 3
OH OH
No. R5 R6 R13 R 4 R15 R16 No. R 5 R 6 R 13 R 4 R 15 R 16
1.13-159 OH H H H H 1.13-159 OH H H H H
1.13-160 OH H H H H 1.13-160 OH H H H H
H  H
1.13-161 OH H H H H 1.13-161 OH H H H H
1.13-162 OH H H H H 1.13-162 OH H H H H
1.13-163 OH H H H H 1.13-163 OH H H H H
1.13-164 OH H H H H 1.13-164 OH H H H H
H  H
1.13-165 OH H H H H 1.13-165 OH H H H H
I  I
1.13-166 OH H H H H 1.13-166 OH H H H H
1.13-167 OH H H H H 1.13-167 OH H H H H
1.13-168 OH H H H H 1.13-168 OH H H H H
0 N  0 N
H  H
1.13-169 OH H H H H 1.13-169 OH H H H H
0  0
1.13-170 OH H H H H 1.13-170 OH H H H H
' O No. R5 R6 R13 R 4 R15 R16 'O No. R 5 R 6 R 13 R 4 R 15 R 16
1.13-209 OnPr H H H H 1.13-209 O n Pr HHHH
1.13-210 0"Pr 0Λ0/ H H CH3 H 1.13-210 0 "Pr 0 Λ 0 / HH CH 3 H
1.13-21 1 OnPr H H H CH3 1.13-21 1 O n Pr HHH CH 3
1.13-212 OnBu F H H H H1.13-212 O n Bu FHHHH
1.13-213 0"Bu CH3 H H H H i.13-214 OnBu OCH3 H H H H 1.13-213 0 "Bu CH 3 HHHH i.13-214 O n Bu OCH 3 HHHH
1.13-215 OnBu H H H H 1.13-215 O n Bu HHHH
1.13-216 OnBu H H CH3 H 1.13-216 O n Bu HH CH 3 H
1.13-217 OnBu H H H CH3 1.13-217 O n Bu HHH CH 3
1.13-224 OSi(Et)3 F H H H H1.13-224 OSi (Et) 3 FHHHH
1.13-225 OSi(Et)3 CH3 H H H H1.13-225 OSi (Et) 3 CH 3 HHHH
1.13-226 OSi(Et)3 OCH3 H H H H 1.13-226 OSi (Et) 3 OCH3 HHHH
1.13-227 OSi(Et)3 H H H H 1.13-227 OSi (Et) 3 HHHH
1.13-228 OSi(Et)3 H H CH3 H 1.13-228 OSi (Et) 3 HH CH 3 H
1.13-229 OSi(Et)3 H H H CH3 1.13-229 OSi (Et) 3 3 HHH CH
1.13-230 OSiMe2t-Bu F H H H H1.13-230 OSiMe 2 t-Bu FHHHH
1.13-231 OSiMe2t-Bu CH3 H H H H1.13-231 OSiMe 2 t-Bu CH 3 HHHH
1.13-232 OSiMe2t-Bu OCH3 H H H H 1.13-232 OSiMe 2 t-Bu OCH3 HHHH
1.13-233 OSiMe2t-Bu H H H H 1.13-233 OSiMe 2 t-Bu HHHH
1.13-234 OSi e2t-Bu H H CH3 H 1.13-234 OSi e 2 t-Bu HH CH 3 H
0^0^ 0 ^ 0 ^
Tabelle 14: Table 14:
No. R5 R6 A5 R7 R18 No. R 5 R 6 A 5 R 7 R 18
1.15-23 OSi(Et)3 S H H 1.15-23 OSi (Et) 3 SHH
1.15-24 OSiMe2t-Bu S H H 1.15-24 OSiMe 2 t-Bu SHH
1.15-25 OAc s H H1.15-25 OAc s H H
0^0^ 0 ^ 0 ^
Tabelle 16: Table 16:
No. R5 R6 A6 A7 R19 R20 R23 R24 No. R 5 R 6 A 6 A 7 R 19 R 20 R 23 R 24
1.16-1 OH CH2 CH2 H H H H 1.16-1 OH CH 2 CH 2 HHHH
1.16-2 OH CH2 CH2 H H H H 1.16-2 OH CH 2 CH 2 HHHH
1.16-3 OH CH2 0 H H H H 1.16-3 OH CH 2 0 HHHH
1.16-4 OH CH2 0 H H H H 1.16-4 OH CH 2 0 HHHH
1.16-5 OH CH2 s H H H H 1.16-5 OH CH 2 s HHHH
1.16-6 OH CH2 s H H H H 1.16-6 OH CH 2 s HHHH
1.16-7 OH CH2 H H H H 1.16-7 OH CH 2 HHHH
1.16-8 OH CH2 H H H H 1.16-8 OH CH 2 HHHH
Tabelle 17:Table 17:
Tabelle 18: Table 18:
No. R5 R6 A9 R31 R32 R34 R35 No. R 5 R 6 A 9 R 31 R32 R 34 R35
1.18-1 OH CH2 H H H H 1.18-1 OH CH 2 HHHH
1.18-2 OH CH2 H H H H 1.18-2 OH CH 2 HHHH
1.18-3 OH 0 H H H H 1.18-3 OH 0 H H H H
1.18-4 OH 0 H H H H 1.18-4 OH 0 H H H H
1.18-5 OH S H H H H 1.18-5 OH S H H H H
1.18-6 OH s H H H H 1.18-6 OH s H H H H
0^0^ No. R5 R6 A9 R3 R32 R34 R35 0 ^ 0 ^ No. R 5 R 6 R 9 A 3 R32 R34 R 35
1.18-7 OH 1.18-7 OH
o^o^ -X- H H H H  o ^ o ^ -X- H H H H
1.18-8 OH ■· · H H H H 1.18-8 OH ■ · · HHHH
1.18-9 OH CH2 H H H H 1.18-9 OH CH 2 HHHH
0 X^ OH  0 X ^ OH
1.18-10 OH CH2 H H H H 1.18-10 OH CH 2 HHHH
1.18-1 1 OH CH2 H H H H 1.18-1 1 OH CH 2 HHHH
1.18-12 OH CH2 H H H H o^o^ h 1.18-12 OH CH 2 HHHH o ^ o ^ h
1.18-13 OAc CH2 H H H H o^o^ 1.18-13 OAc CH 2 HHHH o ^ o ^
1.18-14 OAc CH2 H H H H 1.18-14 OAc CH 2 HHHH
1.18-15 OSiEi3 CH2 H H H H o^o^ 1.18-15 OSiEi 3 CH 2 HHHH o ^ o ^
1.18-16 OSiEia CH2 H H H H 1.18-16 OSiEia CH 2 HHHH
Tabelle 20: Table 20:
No. R5 R6 A5 R17 R18 No. R 5 R 6 A 5 R 17 R 18
1.22-1 OH S H H 1.22-1 OH S H H
I.22-2 OH S H H i.22-3 OH S H H I.22-2 OH S H H i.22-3 OH S H H
O^H  O ^ H
I.22-4 OH s H H I.22-4 OH s H H
I.22-5 OH s CH3 H I.22-5 OH s CH 3 H
I.22-6 OH s CH3 CH3 I.22-6 OH s CH 3 CH 3
I.22-7 OH s H CH3 Tabelle 23:I.22-7 OH s H CH 3 Table 23:
Tabelle 25: Table 25:
Tabelle 27: Table 27:
Tabelle 28: Tabelle 29:Table 28: Table 29:
Tabelle 33: Table 33:
Tabelle 34: Table 34:
Tabelle 35: Table 35:
Tabelle 36:Table 36:
Tabelle 37:Table 37:
o. R5 R6 A6 A7 R 9 R20 R23 R24 -12 OH CH2 CH2 H H H H -13 OH o. R 5 R 6 A 6 A 7 R 9 R 20 R 23 R 24 -12 OH CH 2 CH 2 HHHH -13 OH
C X CH2 0 H H H H T OH -14 OH X CH2 s H H H H CX CH 2 0HHHHT OH -14 OH X CH 2 s HHHH
0^ OH  0 ^ OH
Spektroskopische Daten ausgewählter Tabellenbeispiele: Spectroscopic data of selected table examples:
Beispiel No. 1.1 -1 : Example No. 1.1 -1:
1H-NMR (400 MHz, CDCb δ, ppm) 7.40 (m, 1 H), 7.29 (m, 1 H), 7.08 (m, 2H), 1 .99 (m, 1 H), 1 .83 (m, 1 H), 1 .74 (br. s, 1 H, OH), 1 .71 (m, 2H), 1 .44 (m, 1 H), 1 .29 (s, 3H), 1 .22 (s, 3H), 1 .21 -1 .12 (m, 2H), 1 .03 (s, 3H). 1H-NMR (400 MHz, CDCb δ, ppm) 7.40 (m, 1H), 7.29 (m, 1H), 7.08 (m, 2H), 1 .99 (m, 1H), 1 .83 (m , 1 H), 1 .74 (br s, 1 H, OH), 1 .71 (m, 2H), 1 .44 (m, 1 H), 1 .29 (s, 3H), 1 .22 (s, 3H), 1 .21 -1 .12 (m, 2H), 1 .03 (s, 3H).
Beispiel No. 1.1 -53:Example No. 1.1 -53:
H-NMR (400 MHz, CDCb δ, ppm) 7.39 (m, 1 H), 7.18 (m, 2H), 7.1 1 (m, 1 H), 2.44 (s, 3H), 1 .99 (m, 1 H), 1 .82 (m, 1 H), 1 .73 (m, 2H), 1 .71 (br. s, 1 H, OH), 1 .44 (m, 1 H), 1 .28 (s, 3H), 1 .24 (s, 3H), 1 .20-1 .13 (m, 2H), 1 .02 (s, 3H).  H-NMR (400 MHz, CDCb δ, ppm) 7.39 (m, 1H), 7.18 (m, 2H), 7.1 1 (m, 1H), 2.44 (s, 3H), 1.99 (m, 1 H), 1 .82 (m, 1H), 1 .73 (m, 2H), 1 .71 (br. S, 1H, OH), 1 .44 (m, 1H), 1 .28 ( s, 3H), 1 .24 (s, 3H), 1 .20-1 .13 (m, 2H), 1 .02 (s, 3H).
Beispiel No. 1.1 -56:Example No. 1.1 -56:
H-NMR (400 MHz, CDCb δ, ppm) 7.63 (m, 1 H), 7.58 (m, 1 H), 7.47 (m, 1 H), 7.38 (m, 1 H), 1 .98 (m, 1 H), 1 .88 (m, 2H), 1 .75 (br. s, 1 H, OH), 1 .72 (m, 2H), 1 .41 (m, 1 H), 1 .21 (s, 3H), 1 .17 (s, 3H), 1 .12 (m, 1 H), 0.96 (s, 3H).  H-NMR (400 MHz, CDCb δ, ppm) 7.63 (m, 1H), 7.58 (m, 1H), 7.47 (m, 1H), 7.38 (m, 1H), 1.98 (m, 1 H), 1 .88 (m, 2H), 1 .75 (brs s, 1 H, OH), 1 .72 (m, 2H), 1 .41 (m, 1 H), 1 .21 ( s, 3H), 1 .17 (s, 3H), 1 .12 (m, 1H), 0.96 (s, 3H).
Beispiel No. 1.1 -57: Example No. 1.1 -57:
H-NMR (400 MHz, CDCb δ, ppm) 7.48 (m, 1 H), 7.31 (m, 1 H), 7.24 (m, 2H), 1 .97 (m, 1 H), 1 .83 (m, 1 H), 1 .77 (br. s, 1 H, OH), 1 .76 (m, 2H), 1 .46 (m, 1 H), 1 .27 (s, 3H), 1 .21 H NMR (400 MHz, CDCb δ, ppm) 7.48 (m, 1H), 7.31 (m, 1H), 7.24 (m, 2H), 1 .97 (m, 1H), 1 .83 (m , 1 H), 1 .77 (br s, 1 H, OH), 1 .76 (m, 2H), 1 .46 (m, 1 H), 1 .27 (s, 3H), 1 .21
(s, 3H), 1 .21 -1 .14 (m, 2H), 1 .03 (s, 3H). Beispiel No.1.1-66: (s, 3H), 1 .21 -1 .14 (m, 2H), 1 .03 (s, 3H). Example No.1.1-66:
1H-NMR (400 MHz, CDCh δ, ppm) 7.40 (m, 1 H), 7.20 (m, 2H), 7.11 (m, 1 H), 2.81 (q, 1 H), 1.99 (m, 1 H), 1.82 (m, 1 H), 1.73 (m, 2H), 1.71 (br. s, 1 H, OH), 1.42 (m, 1 H), 1.26 1 H-NMR (400 MHz, CDCh δ, ppm) 7.40 (m, 1H), 7.20 (m, 2H), 7.11 (m, 1H), 2.81 (q, 1H), 1.99 (m, 1H ), 1.82 (m, 1H), 1.73 (m, 2H), 1.71 (br s, 1H, OH), 1.42 (m, 1H), 1.26
(s, 3H), 1.22 (t, 3H), 1.20 (s, 3H), 1.19-1.12 (m, 2H), 1.03 (s, 3H). (s, 3H), 1.22 (t, 3H), 1.20 (s, 3H), 1.19-1.12 (m, 2H), 1.03 (s, 3H).
Beispiel No.1.1-67:Example No.1.1-67:
H-NMR (400 MHz, CDCh δ, ppm) 7.41 (m, 1 H), 7.29 (m, 2H), 7.11 (m, 1 H), 3.45 (sepi, 1 H), 2.00 (m, 1 H), 1.82 (m, 1 H), 1.74 (m, 2H), 1.72 (br. s, 1 H, OH), 1.44 (m, 1 H), 1.28 (s, 3H), 1.27 (d, 3H), 1.23 (d, 3H), 1.21 (s.3H), 1.20-1.10 (m.2H), 1.03 (s, 3H).  H-NMR (400 MHz, CDCh δ, ppm) 7.41 (m, 1H), 7.29 (m, 2H), 7.11 (m, 1H), 3.45 (sepi, 1H), 2.00 (m, 1H) , 1.82 (m, 1H), 1.74 (m, 2H), 1.72 (brs s, 1H, OH), 1.44 (m, 1H), 1.28 (s, 3H), 1.27 (d, 3H), 1.23 (d, 3H), 1.21 (s.3H), 1.20-1.10 (m.2H), 1.03 (s, 3H).
Beispiel No.1.1-70:Example No.1.1-70:
H-NMR (400 MHz, CDCh 6, ppm) 7.46 (m, 1H), 7.31 (m, 2H), 7.16 (m, 1H), 6.72-6.36 (t, 1 H), 1.92 (m, 1 H), 1.84 (m, 1 H), 1.76 (br. s, 1 H, OH), 1.72 (m, 2H), 1.42 (m, 1 H), H NMR (400 MHz, CDCh6, ppm) 7.46 (m, 1H), 7.31 (m, 2H), 7.16 (m, 1H), 6.72-6.36 (t, 1H), 1.92 (m, 1H) , 1.84 (m, 1H), 1.76 (brs s, 1H, OH), 1.72 (m, 2H), 1.42 (m, 1H),
1.20 (s, 3H), 1.16 (s, 3H), 1.20-1.10 (m, 2H), 0.96 (s, 3H). 1.20 (s, 3H), 1.16 (s, 3H), 1.20-1.10 (m, 2H), 0.96 (s, 3H).
Beispiel No.1.1-71: Example No.1.1-71:
1H-NMR (400 MHz, CDCh δ, ppm) 9.87 (s, 1 H), 7.92 (m, 1 H), 7.53 (m, 2H), 7.43 (m, 1 H), 2.77 (br. s, 1 H, OH), 1.97 (m, 1 H), 1.79 (m, 1 H), 1.73 (m, 1 H), 1.46 (m, 2H), 1.27 (s, 3H), 1.22 (s, 3H), 1.25-1.14 (m, 2H), 1.04 (s, 3H). 1 H-NMR (400 MHz, CDCh δ, ppm) 9.87 (s, 1H), 7.92 (m, 1H), 7.53 (m, 2H), 7.43 (m, 1H), 2.77 (br. S, 1 H, OH), 1.97 (m, 1H), 1.79 (m, 1H), 1.73 (m, 1H), 1.46 (m, 2H), 1.27 (s, 3H), 1.22 (s, 3H) , 1.25-1.14 (m, 2H), 1.04 (s, 3H).
Beispiel No.1.1-74:Example No.1.1-74:
H-NMR (400 MHz, CDCh δ, ppm) 7.47 (m, 2H), 7.33 (m, 1H), 7.29 (m, 1H), 3.89 (s, 2H), 2.00 (m, 1 H), 1.87 (br. s, 1 H, OH), 1.79 (m, 1 H), 1.76 (m, 2H), 1.46 (m, 1 H), 1.28 (s, 3H), 1.23 (s, 3H), 1.22-1.15 (m, 2H), 1.03 (s, 3H).  H-NMR (400 MHz, CDCh δ, ppm) 7.47 (m, 2H), 7.33 (m, 1H), 7.29 (m, 1H), 3.89 (s, 2H), 2.00 (m, 1H), 1.87 ( br. s, 1H, OH), 1.79 (m, 1H), 1.76 (m, 2H), 1.46 (m, 1H), 1.28 (s, 3H), 1.23 (s, 3H), 1.22-1.15 (m, 2H), 1.03 (s, 3H).
Beispiel No.1.1-75:Example No.1.1-75:
H-NMR (400 MHz, CDCh δ, ppm) 8.52 (s, 1 H), 7.73 (m, 1 H), 7.60 (m, 1 H), 7.48-7.32 (m, 3H), 2.08 (m, 1H), 1.90 (br. m, 1H, OH), 1.80 (m, 1H), 1.77 (m, 1H), 1.48 (m, 2H), 1.28 (s, 3H), 1.20 (s, 3H), 1.26-1.15 (m, 2H), 1.08 (s, 3H). Beispiel No.1.1-77: H-NMR (400 MHz, CDCh δ, ppm) 8.52 (s, 1H), 7.73 (m, 1H), 7.60 (m, 1H), 7.48-7.32 (m, 3H), 2.08 (m, 1H , 1.90 (br, m, 1H, OH), 1.80 (m, 1H), 1.77 (m, 1H), 1.48 (m, 2H), 1.28 (s, 3H), 1.20 (s, 3H), 1.26- 1.15 (m, 2H), 1.08 (s, 3H). Example No.1.1-77:
Isomer 1 - 1H-NMR (400 MHz, CDCh δ, ppm) 8.53 (s, 1 H), 7.88 (m, 1 H), 7.43 (m, 1 H), 7.29 (m, 2H), 4.24 (q, 2H), 1.99 (m, 1H), 1.81 (m, 1H), 1.77 (br. s, 1H, OH), 1.73 (m, 2H), 1.43 (m, 1 H), 1.32 (t, 3H), 1.28 (s, 3H), 1.22 (s, 3H), 1.20-1.12 (m, 2H), 1.03 (s, 3H); Isomer 2 - 8.39 (m, 1 H), 7.85 (s, 1 H), 7.48 (m, 1 H), 7.32 (m, 2H), 4.27 (q, 2H), 1.93 (m, 1 H), 1.80 (m, 1 H), 1.74 (m, 2H), 1.69 (br. s, 1 H, OH), 1.40 (m, 1 H), 1.34 (t, 3H), 1.24 (s, 3H), 1.21-1.12 (m, 2H), 1.17 (s,3H), 0.96 (s, 3H); Isomer 1 - 1 H-NMR (400 MHz, CDCh δ, ppm) 8.53 (s, 1H), 7.88 (m, 1H), 7.43 (m, 1H), 7.29 (m, 2H), 4.24 (q , 2H), 1.99 (m, 1H), 1.81 (m, 1H), 1.77 (br.s, 1H, OH), 1.73 (m, 2H), 1.43 (m, 1H), 1.32 (t, 3H) , 1.28 (s, 3H), 1.22 (s, 3H), 1.20-1.12 (m, 2H), 1.03 (s, 3H); Isomer 2 - 8.39 (m, 1H), 7.85 (s, 1H), 7.48 (m, 1H), 7.32 (m, 2H), 4.27 (q, 2H), 1.93 (m, 1H), 1.80 (m, 1H), 1.74 (m, 2H), 1.69 (br s, 1H, OH), 1.40 (m, 1H), 1.34 (t, 3H), 1.24 (s, 3H), 1.21- 1.12 (m, 2H), 1.17 (s, 3H), 0.96 (s, 3H);
Beispiel No.1.1-79: Example No.1.1-79:
1H-NMR (400 MHz, CDCh δ, ppm) 7.48 (m, 1H), 7.31 (m, 1H).7.18 (m, 1H), 7.07 (d, 1 H), 2.33 (s, 3H), 1.98 (m, 1 H), 1.80 (br. s, 1 H, OH), 1.79-1.70 (m, 3H), 1.44 (m, 1 H), 1.26 (s, 3H), 1.20 (s, 3H), 1.19-1.11 (m, 2H), 1.01 (s, 3H). 1H-NMR (400 MHz, CDCh δ, ppm) 7.48 (m, 1H), 7.31 (m, 1H) .7.18 (m, 1H), 7.07 (d, 1H), 2.33 (s, 3H), 1.98 ( m, 1H), 1.80 (brs s, 1H, OH), 1.79-1.70 (m, 3H), 1.44 (m, 1H), 1.26 (s, 3H), 1.20 (s, 3H), 1.19 -1.11 (m, 2H), 1.01 (s, 3H).
Beispiel No.1.1-87: Example No.1.1-87:
1H-NMR (400 MHz, CDCh δ, ppm) 8.10 (d, 1H, NH), 7.35 (m.2H).7.30 (m, 2H), 6.941H-NMR (400 MHz, CDCh δ, ppm) 8.10 (d, 1H, NH), 7.35 (m.2H) .7.30 (m, 2H), 6.94
(m, 1 H), 2.00 (m, 1 H), 1.80 (m, 2H), 1.75 (m, 1 H), 1.70 (br. s, 1 H, OH), 1.52 (s, 9H), 1.48 (m, 1 H), 1.30 (s, 3H), 1.27 (s, 3H), 1.26-1.14 (m, 2H), 1.06 (s, 3H). (m, 1H), 2.00 (m, 1H), 1.80 (m, 2H), 1.75 (m, 1H), 1.70 (br, s, 1H, OH), 1.52 (s, 9H), 1.48 (m, 1H), 1.30 (s, 3H), 1.27 (s, 3H), 1.26-1.14 (m, 2H), 1.06 (s, 3H).
Beispiel No.1.1-88: Example No.1.1-88:
1H-NMR (400 MHz, CDCh δ, ppm) 7.59 (d, 1 H), 7.43 (m, 1 H), 7.33 (m, 1 H), 7.11 (m, 1H), 7.02 (br. s, 1H, NH), 3.02 (s, 3H), 1.99 (m, 1H), 1.86 (br. s, 1H, OH), 1.80 (m, 1H), 1.75 (m, 2H), 1.48 (m, 1H), 1.28 (s, 3H), 1.26 (s, 3H), 1.27-1.17 (m, 2H), 1.04 (s, 3H). 1H-NMR (400 MHz, CDCh δ, ppm) 7.59 (d, 1H), 7.43 (m, 1H), 7.33 (m, 1H), 7.11 (m, 1H), 7.02 (br. S, 1H , NH), 3.02 (s, 3H), 1.99 (m, 1H), 1.86 (br, s, 1H, OH), 1.80 (m, 1H), 1.75 (m, 2H), 1.48 (m, 1H), 1.28 (s, 3H), 1.26 (s, 3H), 1.27-1.17 (m, 2H), 1.04 (s, 3H).
Beispiel No.1.1-91: Example No.1.1-91:
1H-NMR (400 MHz, CDCh δ, ppm) 7.58 (d, 1 H), 7.51 (m, 1 H), 7.43 (m, 1 H), 7.21 (m, 1H), 5.33 (br. s, 2H, NH), 2.37 (br. s, 1H, OH), 1.94 (m, 1H), 1.82 (m, 2H), 1.73 (m, 1H), 1.48 (m, 1H), 1.28 (s, 3H), 1.26 (s, 3H), 1.26-1.17 (m, 2H), 1.03 (s, 3H). 1H-NMR (400 MHz, CDCh δ, ppm) 7.58 (d, 1H), 7.51 (m, 1H), 7.43 (m, 1H), 7.21 (m, 1H), 5.33 (br. S, 2H , NH), 2.37 (brs s, 1H, OH), 1.94 (m, 1H), 1.82 (m, 2H), 1.73 (m, 1H), 1.48 (m, 1H), 1.28 (s, 3H), 1.26 (s, 3H), 1.26-1.17 (m, 2H), 1.03 (s, 3H).
Beispiel No.1.1-99:Example No.1.1-99:
H-NMR (400 MHz, CDCh δ, ppm) 7.50 (m, 1 H), 7.45 (d, 1 H), 7.30 (m, 1 H), 7.12 (m, H-NMR (400 MHz, CDCh δ, ppm) 7.50 (m, 1H), 7.45 (d, 1H), 7.30 (m, 1H), 7.12 (m,
2H), 6.95 (dd, 1H), 6.67 (d, 1H), 1.92 (m, 1H), 1.76 (m, 1H), 1.69 (m, 2H), 1.61 (br. s, 1 H, OH), 1.41 (m, 1 H), 1.18-1.04 (m, 2H), 1.11 (s, 3H), 1.06 (s, 3H), 0.94 (s, 3H). Beispiel No.1.1-116: 2H), 6.95 (dd, 1H), 6.67 (d, 1H), 1.92 (m, 1H), 1.76 (m, 1H), 1.69 (m, 2H), 1.61 (br.s, 1H, OH), 1.41 (m, 1H), 1.18-1.04 (m, 2H), 1.11 (s, 3H), 1.06 (s, 3H), 0.94 (s, 3H). Example No.1.1-116:
1H-NMR (400 MHz, CDCh δ, ppm) 7.91 (d, 1 H), 7.51 (d, 1 H), 7.44 (dd, 1 H), 7.33 (dd, 1 H), 3.90 (s, 3H), 2.00 (m, 1 H), 1.86 (m, 1 H), 1.72 (m, 2H), 1.42 (m, 1 H), 1.28 (s, 3H), 1.21 (s, 3H), 1.20-1.10 (m, 2H), 1.02 (s, 3H). 1 H-NMR (400 MHz, CDCh δ, ppm) 7.91 (d, 1H), 7.51 (d, 1H), 7.44 (dd, 1H), 7.33 (dd, 1H), 3.90 (s, 3H ), 2.00 (m, 1H), 1.86 (m, 1H), 1.72 (m, 2H), 1.42 (m, 1H), 1.28 (s, 3H), 1.21 (s, 3H), 1.20-1.10 (m, 2H), 1.02 (s, 3H).
Beispiel No.1.1-123: Example No.1.1-123:
1H-NMR (400 MHz, CDCh δ, ppm) 7.70 (s, 1 H), 7.40 (d, 1 H), 7.21 (m, 1 H), 3.90 (s, 3H), 2.38 (s, 3H), 1.98 (m, 1H), 1.87 (m, 1H), 1.73 (m, 2H), 1.42 (m, 2H), 1.28 (s, 3H), 1.21 (s, 3H), 1.18 (m, 2H), 1.02 (s, 3H). 1 H-NMR (400 MHz, CDCh δ, ppm) 7.70 (s, 1H), 7.40 (d, 1H), 7.21 (m, 1H), 3.90 (s, 3H), 2.38 (s, 3H) , 1.98 (m, 1H), 1.87 (m, 1H), 1.73 (m, 2H), 1.42 (m, 2H), 1.28 (s, 3H), 1.21 (s, 3H), 1.18 (m, 2H), 1.02 (s, 3H).
Beispiel No.1.1-125:Example No.1.1-125:
H-NMR (400 MHz, CDCb δ, ppm) 7.89 (d, 1 H), 7.51 (d, 1 H), 7.42 (t, 1 H), 7.32 (t, 1 H), H-NMR (400 MHz, CDCbδ, ppm) 7.89 (d, 1H), 7.51 (d, 1H), 7.42 (t, 1H), 7.32 (t, 1H),
4.39 (q, 2H), 2.00 (m, 1H), 1.88 (m, 2H), 1.78-1.65 (m, 3H), 1.40 (m, 4H), 1.21 (s, 3H), 1.19 (s, 3H), 1.11 (m, 1H), 1.01 (s, 3H). 4.39 (q, 2H), 2.00 (m, 1H), 1.88 (m, 2H), 1.78-1.65 (m, 3H), 1.40 (m, 4H), 1.21 (s, 3H), 1.19 (s, 3H) , 1.11 (m, 1H), 1.01 (s, 3H).
Beispiel No.1.1-126: Example No.1.1-126:
1H-NMR (400 MHz, CDCb δ, ppm) 7.77 (d, 1 H), 7.49 (d, 1 H), 7.40 (t, 1 H), 7.30 (t, 1 H), 2.00 (m, 1 H), 1.88 (m, 1 H), 1.71 (m, 2H), 1.58 (m, 1 H), 1.41 (m, 1 H), 1.27 (s, 3H), 1.21 (s, 3H), 1.17 (m, 2H), 1.01 (s, 3H). 1 H-NMR (400 MHz, CDCbδ, ppm) 7.77 (d, 1H), 7.49 (d, 1H), 7.40 (t, 1H), 7.30 (t, 1H), 2.00 (m, 1 H), 1.88 (m, 1H), 1.71 (m, 2H), 1.58 (m, 1H), 1.41 (m, 1H), 1.27 (s, 3H), 1.21 (s, 3H), 1.17 ( m, 2H), 1.01 (s, 3H).
Beispiel No.1.1-127: Example No.1.1-127:
1H-NMR (400 MHz, CDCb δ, ppm) 7.93 (d, 1 H), 7.52 (d, 1 H), 7.44 (m, 2H), 7.40-7.32 (m, 5H), 5.37 (s, 2H), 1.99-1.90 (m, 1 H), 1.86 (m, 1 H), 1.76-1.58 (m, 3H), 1.45-1.39 1 H-NMR (400 MHz, CDCb δ, ppm) 7.93 (d, 1H), 7.52 (d, 1H), 7.44 (m, 2H), 7.40-7.32 (m, 5H), 5.37 (s, 2H ), 1.99-1.90 (m, 1H), 1.86 (m, 1H), 1.76-1.58 (m, 3H), 1.45-1.39
(m, 1H), 1.22 (s, 3H), 1.19/ 1.16 (s, 3H), 1.18- 1.10 (m, 2H), 0.98/0.96 (s, 3H). (m, 1H), 1.22 (s, 3H), 1.19 / 1.16 (s, 3H), 1.18-1.10 (m, 2H), 0.98 / 0.96 (s, 3H).
Beispiel No.1.1-129:Example No.1.1-129:
H-NMR (400 MHz, CDCh δ, ppm) 7.90 (d, 1 H), 7.53 (d, 1 H), 7.43 (m, 1 H), 7.33 (m, 1H), 4.30 (t, 2H), 2.09 (br. s, 1H, OH), 2.00 (m, 1H), 1.88 (m, 1H), 1.81-1.73 (m, 4H), 1.44 (m, 1H), 1.27 (s, 3H), 1.23 (s, 3H), 1.19 (m, 1H), 1.16 (m, 1H), 1.03 (t, 3H), 1.02 (s, 3H). Beispiel No.1.1-162: H NMR (400 MHz, CDCh δ, ppm) 7.90 (d, 1H), 7.53 (d, 1H), 7.43 (m, 1H), 7.33 (m, 1H), 4.30 (t, 2H), 2.09 (brs s, 1H, OH), 2.00 (m, 1H), 1.88 (m, 1H), 1.81-1.73 (m, 4H), 1.44 (m, 1H), 1.27 (s, 3H), 1.23 ( s, 3H), 1.19 (m, 1H), 1.16 (m, 1H), 1.03 (t, 3H), 1.02 (s, 3H). Example No.1.1-162:
1H-NMR (400 MHz, CDCb δ, ppm) 8.05 (m, 1 H), 7.62 (br. m, 1 H, NH), 7.49 (m, 1 H), 7.42 (m, 2H), 4.29 (m, 2H), 2.32 (t, 1H), 2.04 (br. s, 1H, OH), 2.00 (m, 1H), 1.82 (m, 1 H-NMR (400 MHz, CDCb δ, ppm) 8.05 (m, 1H), 7.62 (br, m, 1H, NH), 7.49 (m, 1H), 7.42 (m, 2H), 4.29 ( m, 2H), 2.32 (t, 1H), 2.04 (brs s, 1H, OH), 2.00 (m, 1H), 1.82 (m,
1H), 1.81-1.73 (m, 2H), 1.48 (m, 1H), 1.29 (s, 3H), 1.24 (s, 3H), 1.21 (m, 1H), 1.19 (m, 1H), 1.04 (s, 3H). 1H), 1.81-1.73 (m, 2H), 1.48 (m, 1H), 1.29 (s, 3H), 1.24 (s, 3H), 1.21 (m, 1H), 1.19 (m, 1H), 1.04 (s , 3H).
Beispiel No. I.3-9:Example No. I.3-9:
H-NMR (400 MHz, CDCb δ, ppm) 7.10 (s, 1H), 3.89 (s, 3H), 2.29 (s, 3H), 2.00 (m, 1 H), 1.88 (m, 1 H), 1.76 (m, 4H), 1.45 (m, 1 H), 1.30 (s, 3H), 1.23 (s, 3H), 1.04 (s, 3H).  H-NMR (400 MHz, CDCb δ, ppm) 7.10 (s, 1H), 3.89 (s, 3H), 2.29 (s, 3H), 2.00 (m, 1H), 1.88 (m, 1H), 1.76 (m, 4H), 1.45 (m, 1H), 1.30 (s, 3H), 1.23 (s, 3H), 1.04 (s, 3H).
Beispiel No. I.4-2: Example No. I.4-2:
1H-NMR (400 MHz, CDCb δ, ppm) 4.22 (q, 2H), 2.33 (m, 4H), 1.92 (m, 2H), 1.70 (m, 4H), 1.40 (m, 2H), 1.30 (t, 3H), 1.20 (s, 4H), 1.12 (d, 5H), 0.98 (d, 4H). Beispiel No. I.4-7: 1 H-NMR (400 MHz, CDCbδ, ppm) 4.22 (q, 2H), 2.33 (m, 4H), 1.92 (m, 2H), 1.70 (m, 4H), 1.40 (m, 2H), 1.30 ( t, 3H), 1.20 (s, 4H), 1.12 (d, 5H), 0.98 (d, 4H). Example No. I.4-7:
H-NMR (400 MHz, CDCb δ, ppm) 3.71 (s, 3H), 2.35 (m, 2H), 2.15 (m, 2H), 1.95 (m, 2H), 1.70 (m, 5H), 1.39 (t, 3H), 1.20 (s, 3H), 1.15 (s, 3H), 0.99 (s, 3H), 0.96 (m, 6H).  H-NMR (400 MHz, CDCb δ, ppm) 3.71 (s, 3H), 2.35 (m, 2H), 2.15 (m, 2H), 1.95 (m, 2H), 1.70 (m, 5H), 1.39 (t , 3H), 1.20 (s, 3H), 1.15 (s, 3H), 0.99 (s, 3H), 0.96 (m, 6H).
Beispiel No. I.5-2:Example No. I.5-2:
H-NMR (400 MHz, CDCb δ, ppm) 4.23 (q, 2H), 2.71-2.61 (m, 4H), 1.93 (m, 3H), 1.80 H NMR (400 MHz, CDCbδ, ppm) 4.23 (q, 2H), 2.71-2.61 (m, 4H), 1.93 (m, 3H), 1.80
(m, 1 H), 1.71 (m, 1 H), 1.40 (m, 1 H), 1.30 (t, 3H), 1.21 (s, 3H), 1.14 (m, 6H), 0.99 (s, 3H). (m, 1H), 1.71 (m, 1H), 1.40 (m, 1H), 1.30 (t, 3H), 1.21 (s, 3H), 1.14 (m, 6H), 0.99 (s, 3H) ,
Beispiel No.1.7-116: Example No.1.7-116:
1H-NMR (400 MHz, CDCb δ, ppm) 7.91 (dd, 1 H), 7.51 (m, 1 H), 7.46 (t, 1 H), 7.34 (t,1H-NMR (400 MHz, CDCb δ, ppm) 7.91 (dd, 1H), 7.51 (m, 1H), 7.46 (t, 1H), 7.34 (t,
1H), 3.90 (s, 3H), 2.40 (s, 1H, OH), 2.30 (m, 1H), 2.00 (m, 2H), 1.80-1.70 (m, 2H), 1.52 (m, 1H), 1.20 (m, 1H), 1.10 (s, 3H), 1.02 (s, 3H), 0.90 (s, 3H). 1H), 3.90 (s, 3H), 2.40 (s, 1H, OH), 2.30 (m, 1H), 2.00 (m, 2H), 1.80-1.70 (m, 2H), 1.52 (m, 1H), 1.20 (m, 1H), 1.10 (s, 3H), 1.02 (s, 3H), 0.90 (s, 3H).
Beispiel No.1.7-123:Example No.1.7-123:
H-NMR (400 MHz, CDCb δ, ppm) 7.71 (s, 1 H), 7.40 (d, 1 H), 7.23 (s, 1 H), 3.90 (s, 3H), 2.38 (s, 3H), 2.30 (m, 1H), 2.00 (m, 2H), 1.80-1.70 (m, 2H), 1.55 (m, 2H), 1.20 (m, 1H), 1.11 (s, 3H), 1.02 (s, 3H), 0.90 (s, 3H). Beispiel No.1.9-2: H-NMR (400 MHz, CDCb δ, ppm) 7.71 (s, 1H), 7.40 (d, 1H), 7.23 (s, 1H), 3.90 (s, 3H), 2.38 (s, 3H), 2.30 (m, 1H), 2.00 (m, 2H), 1.80-1.70 (m, 2H), 1.55 (m, 2H), 1.20 (m, 1H), 1.11 (s, 3H), 1.02 (s, 3H) , 0.90 (s, 3H). Example No.1.9-2:
1H-NMR (400 MHz, CDCh δ, ppm) 7.43 (d, 1 H), 7.11 (d, 1 H), 3.89 (s, 3H), 2.34 (m, 1 H), 2.31 (m, 1 H), 2.06 (m, 1 H), 2.02 / 1.98 (br. s, 1 H, OH), 1.81 (m, 1 H), 1.73 (m, 1 H), 1.52 (m, 1H), 1.22 (m, 1H), 1.12 (s, 3H), 1.04/ 1.03 (s, 3H), 0.90/0.87 (s, 3H). 1 H-NMR (400 MHz, CDCh δ, ppm) 7.43 (d, 1H), 7.11 (d, 1H), 3.89 (s, 3H), 2.34 (m, 1H), 2.31 (m, 1H ), 2.06 (m, 1H), 2.02 / 1.98 (br s, 1H, OH), 1.81 (m, 1H), 1.73 (m, 1H), 1.52 (m, 1H), 1.22 (m , 1H), 1.12 (s, 3H), 1.04 / 1.03 (s, 3H), 0.90 / 0.87 (s, 3H).
Beispiel No. I.9-9:Example No. I.9-9:
H-NMR (400 MHz, CDCh δ, ppm) 7.10 (s, 1 H), 3.89 (s, 3H), 2.36 (m, 1 H), 2.28 (s, H-NMR (400 MHz, CDCh δ, ppm) 7.10 (s, 1H), 3.89 (s, 3H), 2.36 (m, 1H), 2.28 (s,
3H), 2.21 (m, 1H), 1.98 (m, 3H), 1.52 (m, 3H), 1.12 (s, 3H), 1.04 (s, 3H), 0.90 (s, 3H). Beispiel No.1.11-2:3H), 2.21 (m, 1H), 1.98 (m, 3H), 1.52 (m, 3H), 1.12 (s, 3H), 1.04 (s, 3H), 0.90 (s, 3H). Example No.1.11-2:
H-NMR (400 MHz, CDCh δ, ppm) 4.22 (q, 2H), 2.68 (m, 4H), 2.28 (m, 1 H), 1.90 (m, 3H), 1.70 (m, 2H), 1.50 (m, 1H), 1.30 (t, 3H), 1.09 (s, 3H), 1.08-0.98-0.88 (s, 3H), 0.99 (s, 3H), 0.89 (s, 3H). Beispiel No.1.13-116:  H-NMR (400 MHz, CDCh δ, ppm) 4.22 (q, 2H), 2.68 (m, 4H), 2.28 (m, 1H), 1.90 (m, 3H), 1.70 (m, 2H), 1.50 ( m, 1H), 1.30 (t, 3H), 1.09 (s, 3H), 1.08-0.98-0.88 (s, 3H), 0.99 (s, 3H), 0.89 (s, 3H). Example No.1.13-116:
1H-NMR (400 MHz, CDCh δ, ppm) 7.90 (d, 1 H), 7.52 (d, 1 H), 7.44 (t, 1 H), 7.34 (t, 1 H), 3.91 (s, 3H), 2.43/2.32 (m, 1H), 2.20/2.16 (m, 1H), 2.02 (m, 1H), 1.85/1.75 (m, 2H), 1.55 (m, 3H), 1.35 (m, 3H), 1.03/0.97 (m, 3H). Beispiel No.1.19-30: 1 H-NMR (400 MHz, CDCh δ, ppm) 7.90 (d, 1H), 7.52 (d, 1H), 7.44 (t, 1H), 7.34 (t, 1H), 3.91 (s, 3H ), 2.43 / 2.32 (m, 1H), 2.20 / 2.16 (m, 1H), 2.02 (m, 1H), 1.85 / 1.75 (m, 2H), 1.55 (m, 3H), 1.35 (m, 3H), 1.03 / 0.97 (m, 3H). Example No.1.19-30:
H-NMR (400 MHz, CDCh δ, ppm) 7.91 (d, 1 H), 7.52 (d, 1 H), 7.43 (t, 1 H), 7.33 (t, 1 H), 3.90 (s, 3H), 2.25 (m, 4H), 2.12 (m, 1H), 2.08 (m, 2H), 1.95 (m, 1H), 1.88-1.55 (m, 6H).  H-NMR (400 MHz, CDCh δ, ppm) 7.91 (d, 1H), 7.52 (d, 1H), 7.43 (t, 1H), 7.33 (t, 1H), 3.90 (s, 3H) , 2.25 (m, 4H), 2.12 (m, 1H), 2.08 (m, 2H), 1.95 (m, 1H), 1.88-1.55 (m, 6H).
Beispiel No. I.20-2:Example No. I.20-2:
H-NMR (400 MHz, CDCh δ, ppm) 7.41 (d, 1 H), 7.11 (d, 1 H), 3.89 (s, 3H), 2.25 (m, H-NMR (400 MHz, CDCh δ, ppm) 7.41 (d, 1H), 7.11 (d, 1H), 3.89 (s, 3H), 2.25 (m,
4H), 2.09 (m, 2H), 1.83 (m, 2H), 1.80 (m, 2H), 1.72 (m, 2H), 1.60 (m, 2H). 4H), 2.09 (m, 2H), 1.83 (m, 2H), 1.80 (m, 2H), 1.72 (m, 2H), 1.60 (m, 2H).
Beispiel No.1.21-30:Example No.1.21-30:
H-NMR (400 MHz, CDCh δ, ppm) 7.91 (d, 1 H), 7.51 (d, 1 H), 7.44 (t, 1 H), 7.34 (t, 1 H), 3.91 (s, 3H), 2.51 (d, 1H), 2.30 (m, 1H), 2.25 (m, 1H), 2.15 (m, 1H), 1.95 (m, 1H), 1.48- 1.30 (m, 6H). Beispiel No.1.21-33: H-NMR (400 MHz, CDCh δ, ppm) 7.91 (d, 1H), 7.51 (d, 1H), 7.44 (t, 1H), 7.34 (t, 1H), 3.91 (s, 3H) , 2.51 (d, 1H), 2.30 (m, 1H), 2.25 (m, 1H), 2.15 (m, 1H), 1.95 (m, 1H), 1.48-1.30 (m, 6H). Example No.1.21-33:
1H-NMR (400 MHz, CDCb δ, ppm) 7.72 (s, 1 H), 7.40 (d, 1 H), 7.23 (m, 1 H), 3.91 (s, 3H), 2.50 (d, 1H), 2.37 (s, 3H), 2.27 (m, 2H), 2.13 (m, 1H), 2.04 (m, 1H), 1.48-1.30 (m, 1 H-NMR (400 MHz, CDCbδ, ppm) 7.72 (s, 1H), 7.40 (d, 1H), 7.23 (m, 1H), 3.91 (s, 3H), 2.50 (d, 1H) , 2.37 (s, 3H), 2.27 (m, 2H), 2.13 (m, 1H), 2.04 (m, 1H), 1.48-1.30 (m,
6H). 6H).
Beispiel No. I.23-30:Example No. I.23-30:
H-NMR (400 MHz, CDCb δ, ppm) 7.91 (d, 1 H), 7.53 (d, 1 H), 7.45 (1, 1 H), 7.34 (t, 1 H), 3.91 (s, 3H), 2.10-2.04 (m, 3H), 1.53 (m, 2H), 1.50 (m, 1H), 1.35 (m, 2H), 1.21 (m, 1H), 0.97/0.92 (m, 3H).  H-NMR (400 MHz, CDCb δ, ppm) 7.91 (d, 1H), 7.53 (d, 1H), 7.45 (1, 1H), 7.34 (t, 1H), 3.91 (s, 3H) , 2.10-2.04 (m, 3H), 1.53 (m, 2H), 1.50 (m, 1H), 1.35 (m, 2H), 1.21 (m, 1H), 0.97 / 0.92 (m, 3H).
Beispiel No. I.25-33: Example No. I.25-33:
1H-NMR (400 MHz, CDCb δ, ppm) 7.73 (s, 1 H), 7.41 (d, 1 H), 7.22 (d, 1 H), 3.90 (s, 3H), 2.37 (s, 3H), 2.12-2.08 (m, 2H), 2.03 (m, 1H), 1.97 (m, 1H), 1.92 (m, 2H), 1.74 (m, 1H), 1.71 (m, 1 H), 1.07 / 1.01 (s, 3H), 0.92 / 0.90 (s, 3H), 0.89 / 0.87 (d, 3H). 1 H-NMR (400 MHz, CDCb δ, ppm) 7.73 (s, 1H), 7.41 (d, 1H), 7.22 (d, 1H), 3.90 (s, 3H), 2.37 (s, 3H) , 2.12-2.08 (m, 2H), 2.03 (m, 1H), 1.97 (m, 1H), 1.92 (m, 2H), 1.74 (m, 1H), 1.71 (m, 1H), 1.07 / 1.01 ( s, 3H), 0.92 / 0.90 (s, 3H), 0.89 / 0.87 (d, 3H).
Beispiel No. I.27-33:Example No. I.27-33:
H-NMR (400 MHz, CDCb δ, ppm) 7.72 (s, 1 H), 7.40 (d, 1 H), 7.23 (m, 1 H), 5.20 (s, 1H), 5.03 (s, 1H), 3.91 (s, 3H), 2.82 (d, 1H), 2.38 (s, 3H), 2.01 (m, 2H), 1.72 (m, 1H), 1.50 (m, 5H).  H-NMR (400 MHz, CDCbδ, ppm) 7.72 (s, 1H), 7.40 (d, 1H), 7.23 (m, 1H), 5.20 (s, 1H), 5.03 (s, 1H), 3.91 (s, 3H), 2.82 (d, 1H), 2.38 (s, 3H), 2.01 (m, 2H), 1.72 (m, 1H), 1.50 (m, 5H).
Beispiel No. I.29-26: Example No. I.29-26:
1H-NMR (400 MHz, CDCb δ, ppm) 7.90 (d, 1 H), 7.52 (d, 1 H), 7.44 (t, 1 H), 7.35 (m, 1H), 3.91 (s, 3H), 2.71 (m, 1H), 2.60 (m, 1H), 2.15 (m, 1H), 1.90 (m, 1H), 1.25 (m, 1H), 1.00 (m, 1H), 0.86 (m, 1H), 0.78 (m, 1H), 0.67 (m, 2H), 0.49 (m, 1H). 1 H-NMR (400 MHz, CDCbδ, ppm) 7.90 (d, 1H), 7.52 (d, 1H), 7.44 (t, 1H), 7.35 (m, 1H), 3.91 (s, 3H) , 2.71 (m, 1H), 2.60 (m, 1H), 2.15 (m, 1H), 1.90 (m, 1H), 1.25 (m, 1H), 1.00 (m, 1H), 0.86 (m, 1H), 0.78 (m, 1H), 0.67 (m, 2H), 0.49 (m, 1H).
Beispiel No.1.31-26: Example No.1.31-26:
1H-NMR (400 MHz, CDCb δ, ppm) 7.91 (s, 1 H), 7.51 (d, 1 H), 7.45 (t, 1 H), 7.35 (t, 1 H), 3.91 (s, 3H), 2.65 (m, 1H), 2.32 (m, 1H), 2.05 (d, 1H), 2.00 (d, 1H), 1.90 (m, 4H), 1.68 (m, 2H), 1.50 (s, 1H), 1.38 (dd, 1H), 1.29-1.13 (m, 3H). Beispiel No. 1.31 -29: 1 H-NMR (400 MHz, CDCb δ, ppm) 7.91 (s, 1H), 7.51 (d, 1H), 7.45 (t, 1H), 7.35 (t, 1H), 3.91 (s, 3H ), 2.65 (m, 1H), 2.32 (m, 1H), 2.05 (d, 1H), 2.00 (d, 1H), 1.90 (m, 4H), 1.68 (m, 2H), 1.50 (s, 1H) , 1.38 (dd, 1H), 1.29-1.13 (m, 3H). Example No. 1.31 -29:
1H-NMR (400 MHz, CDCh δ, ppm) 7.73 (s. 1 H), 7.50 (d, 1 H), 7.23 (d, 1 H), 3.91 (s, 3H), 2.65 (m, 1 H), 2.38 (s, 3H), 2.30 (m, 2H), 2.19 (m, 2H), 2.10 (m, 1 H), 2.05 (m, 1 H), 2.00 1 H-NMR (400 MHz, CDCh δ, ppm) 7.73 (see 1 H), 7.50 (d, 1 H), 7.23 (d, 1 H), 3.91 (s, 3H), 2.65 (m, 1 H ), 2.38 (s, 3H), 2.30 (m, 2H), 2.19 (m, 2H), 2.10 (m, 1H), 2.05 (m, 1H), 2.00
(m, 1 H), 1 .69 (m, 3H), 1 .50 (s, 1 H), 1 .38 (m, 1 H), 1 .24 (m, 2H). (m, 1H), 1 .69 (m, 3H), 1 .50 (s, 1H), 1 .38 (m, 1H), 1 .24 (m, 2H).
Beispiel No. I.33-26:Example No. I.33-26:
H-NMR (400 MHz, CDCh δ, ppm) 7.91 (d, 1 H), 7.52 (d, 1 H), 7.45 (t, 1 H), 7.34 (t, 1 H), 3.91 (s, 3H), 2.31 (m, 1 H), 2.00 (m, 1 H), 1 .80 (m, 1 H), 1 .53 (m, 3H), 1 .21 (m, 1 H), 1 .10 (s, 3H), 1 .02 (s, 3H), 0.90 (s, 3H), 1 .03/0.95/0.87 (s, 1 H).  H NMR (400 MHz, CDCh δ, ppm) 7.91 (d, 1H), 7.52 (d, 1H), 7.45 (t, 1H), 7.34 (t, 1H), 3.91 (s, 3H) , 2.31 (m, 1H), 2.00 (m, 1H), 1 .80 (m, 1H), 1 .53 (m, 3H), 1 .21 (m, 1H), 1 .10 ( s, 3H), 1 .02 (s, 3H), 0.90 (s, 3H), 1 .03 / 0.95 / 0.87 (s, 1H).
Beispiel No. I.35-26:Example No. I.35-26:
H-NMR (400 MHz, CDCh δ, ppm) 7.91 (d, 1 H), 7.56 (d, 1 H), 7.45 (dd, 1 H), 7.35 (dd, 1 H), 3.90 (s, 3H), 2.22 (s, 1 H), 1 .92 (m, 1 H), 1 .25 (s, 3H), 1 .20 (m, 2H), 1 .15 (d, 3H), 1 .09 (m, 4H), 1 .07 (m, 3H).  H NMR (400 MHz, CDCh δ, ppm) 7.91 (d, 1H), 7.56 (d, 1H), 7.45 (dd, 1H), 7.35 (dd, 1H), 3.90 (s, 3H) , 2.22 (s, 1H), 1 .92 (m, 1H), 1 .25 (s, 3H), 1 .20 (m, 2H), 1 .15 (d, 3H), 1 .09 ( m, 4H), 1 .07 (m, 3H).
Beispiel No. 1.35-29: Example No. 1.35-29:
1H-NMR (400 MHz, CDCh δ, ppm) 7.71 (s, 1 H), 7.42 (d, 1 H), 7.22 (m, 1 H), 3.90 (s, 3H), 2.38 (s, 3H), 1 .98 (m, 3H), 1 .30 (m, 1 H), 1 .23 (m, 3H), 1 .14 (d, 3H), 1 .06 (m, 6H). Beispiel No. I.37-2: 1 H-NMR (400 MHz, CDCh δ, ppm) 7.71 (s, 1H), 7.42 (d, 1H), 7.22 (m, 1H), 3.90 (s, 3H), 2.38 (s, 3H) , 1 .98 (m, 3H), 1 .30 (m, 1H), 1 .23 (m, 3H), 1 .14 (d, 3H), 1 .06 (m, 6H). Example No. I.37-2:
H-NMR (400 MHz, CDCh δ, ppm) 4.21 (q, 2H), 2.38-2.20 (m, 5H), 1 .88 (m, 2H), 1 .48 (m, 2H), 1 .30 (t, 3H), 1 .15 (m, 2H), 1 .07 (m, 4H), 0.98 (s, 6H), 0.88 (s, 6H).  H-NMR (400 MHz, CDCh δ, ppm) 4.21 (q, 2H), 2.38-2.20 (m, 5H), 1.88 (m, 2H), 1.48 (m, 2H), 1.30 ( t, 3H), 1 .15 (m, 2H), 1 .07 (m, 4H), 0.98 (s, 6H), 0.88 (s, 6H).
Gegenstand der vorliegenden Erfindung ist somit die Verwendung mindestens einer Verbindung, ausgewählt aus der Gruppe, bestehend aus erfindungsgemäß The present invention thus relates to the use of at least one compound selected from the group consisting of according to the invention
substituierten l -(Arylethinyl)-, l-(Heteroarylethinyl)-, l-(Heterocyclylethinyl)- und 1 - (Cyloalkenylethinyl)-bicycloalkanolen der allgemeinen Formel (I), sowie von beliebigen Mischungen dieser erfindungsgemäßen substituierten l -(Arylethinyl)-, 1 - (Heteroarylethinyl)-, l -(Heterocyclylethinyl)- und 1 -(Cyloalkenylethinyl)-bicycloalkanole der allgemeinen Formel (I) mit weiteren agrochemischen Wirkstoffen, zur Steigerung der Widerstandsfähigkeit von Pflanzen gegenüber abioti sehen Stressfaktoren, bevorzugt Trockenstress, sowie zur Stärkung des Pflanzenwachstums und/oder zur Erhöhung des Pflanzenertrags. Weiterer Gegenstand der vorliegenden Erfindung ist eine Sprühlösung zur Behandlung von Pflanzen, enthaltend eine zur Steigerung der Widerstandsfähigkeit von Pflanzen gegenüber abiotischen Stressfaktoren wirksame Menge von mindestens einer substituted L- (arylethynyl) -, L- (heteroarylethynyl) -, L- (heterocyclylethynyl) - and 1 - (cycloalkenylethynyl) -bicycloalkanols of the general formula (I), as well as any desired mixtures of these inventive substituted L- (arylethynyl) -, 1 - (heteroarylethynyl) -, l - (heterocyclylethynyl) - and 1 - (cycloalkenylethynyl) bicycloalkanols of general formula (I) with other agrochemical active ingredients, to increase the resistance of plants to abiotic stress factors, preferably drought stress, and to strengthen the plant Plant growth and / or increase the plant yield. A further subject of the present invention is a spray solution for the treatment of plants, comprising an amount of at least one effective for increasing the resistance of plants to abiotic stress factors
Verbindung, ausgewählt aus der Gruppe, bestehend aus erfindungsgemäß A compound selected from the group consisting of according to the invention
substituierten 1 -(Arylethinyi)-, l-(Heteroarylethinyl)-, l-(Heterocyclylethinyl)- und 1 - (Cyloalkenylethinyl)-bicycloalkanolen, der allgemeinen Formel (I). Zu den dabei relativierbaren abiotischen Streßbedingungen können zum Beispiel Hitze, Dürre, Kälte- und Trockenstress (Stress verursacht durch Trockenheit und/oder Wassenmangel), osmotischer Streß, Staunässe, erhöhter Bodensalzgehalt, erhöhtes Ausgesetztsein an Mineralien, Ozonbedingungen, Starklichtbedingungen, beschränkte Verfügbarkeit von S ti ckstoff n ä h rstoff e n , beschränkte Verfügbarkeit von Phosphornährstoffen zählen. substituted 1 - (arylethinyi) -, 1- (heteroarylethynyl) -, 1- (heterocyclylethynyl) - and 1 - (cycloalkenylethynyl) -bicycloalkanols, of the general formula (I). For example, heat, drought, cold and dry stress (stress caused by drought and / or water deficiency), osmotic stress, waterlogging, increased soil salt content, increased exposure to minerals, ozone conditions, high light conditions, limited availability of S ti nutrients, limited availability of phosphorus nutrients.
In einer Ausführungsform kann beispielsweise vorgesehen sein, dass die For example, in one embodiment, it may be provided that the
erfindungsgemäß vorgesehenen Verbindungen, d. h. die entsprechenden Compounds provided according to the invention, d. H. the corresponding
substituierten 1 -(Arylethinyi)-, l-(Heteroarylethinyl)-, l-(Heterocyclylethinyl)- und 1 - (Cyloalkenylethinyl)-bicycloalkanole der allgemeinen Formel (I), durch eine substituted 1 - (arylethinyi) -, 1- (heteroarylethynyl) -, 1- (heterocyclylethynyl) - and 1 - (cycloalkenylethynyl) -bicycloalkanols of the general formula (I), by a
Sprühapplikation auf entsprechende zu behandelnde Pflanzen oder Pflanzenteile aufgebracht werden. Die erfindungsgemäß vorgesehene Verwendung der Spray application can be applied to appropriate plants or plant parts to be treated. The inventively provided use of the
Verbindungen der allgemeinen Formel (I) oder deren Salze erfolgt vorzugsweise mit einer Dosierung zwischen 0,00005 und 3 kg/ha, besonders bevorzugt zwischen 0,0001 und 2 kg/ha, insbesondere bevorzugt zwischen 0.0005 und 1 kg/ha, im Speziellen bevorzugt zwischen 0,001 und 0,25 kg/ha. Wenn im Rahmen der vorliegenden Compounds of the general formula (I) or salts thereof are preferably present at a dosage of between 0.00005 and 3 kg / ha, more preferably between 0.0001 and 2 kg / ha, particularly preferably between 0.0005 and 1 kg / ha, especially preferred between 0.001 and 0.25 kg / ha. If under the present
Erfindung Abscisinsäure gleichzeitig mit substituierten 1 -(Arylethinyi)-, 1 - (Heteroarylethinyl)-, 1 -(Heterocyclylethinyl)- und 1 -(Cyloalkenylethinyl)- bicycloalkanolen der allgemeinen Formel (I), beispielsweise in Rahmen einer gemeinsamen Zubereitung oder Formulierung verwendet wird, so erfolgt die Invention abscisic acid is used simultaneously with substituted 1 - (arylethinyi) -, 1 - (heteroarylethynyl) -, 1 - (heterocyclylethynyl) - and 1 - (cycloalkenylethynyl) - bicycloalkanols of the general formula (I), for example in the context of a common preparation or formulation , then the
Zumischung von Abscisinsäure dabei vorzugsweise in einer Dosierung zwischen 0.0001 und 3 kg/ha, besonders bevorzugt zwischen 0.001 und 2 kg/ha, insbesondere bevorzugt zwischen 0.005 und 1 kg/ha, im Speziellen bevorzugt zwischen 0.006 und 0.25 kg/ha. Admixing of abscisic acid preferably in a dosage between 0.0001 and 3 kg / ha, more preferably between 0.001 and 2 kg / ha, particularly preferably between 0.005 and 1 kg / ha, in particular preferably between 0.006 and 0.25 kg / ha.
Unter der Bezeichnung Resistenz bzw. Widerstandsfähigkeit gegenüber abiotischem Stress werden im Rahmen der vorliegenden Erfindung verschiedenartige Vorteile für Pflanzen verstanden. Solche vorteilhaften Eigenschaften äußern sich beispielsweise in den nachfolgend genannten verbesserten Pflanzencharakteristika: verbessertes Wurzelwachstum hinsichtlich Oberfläche und Tiefe, vermehrte Ausläuferbildung oder Bestockung, stärkere und produktivere Ausläufer und Bestockungstriebe, The term resistance or resistance to abiotic stress in the context of the present invention, various advantages for Plants understood. Such advantageous properties are manifested, for example, in the following improved plant characteristics: improved root growth in terms of surface area and depth, increased lagging or tillering, stronger and more productive shoots and tillers,
Verbesserung des Sproßwachstums, erhöhte Standfestigkeit, vergrößerte Improvement of shoot growth, increased stability, increased
Sprossbasisdurchmesser, vergrößerte Blattfläche, höhere Erträge an Nähr- und Inhaltsstoffen, wie z.B. Kohlenhydrate, Fette, öle, Proteine, Vitamine, Mineralstoffe, ätherische öle, Farbstoffe, Fasern, bessere Faserqualität, früheres Blühen, gesteigerte Blütenanzahl, reduzierter Gehalt an toxischen Produkten wie Mycotoxine, reduzierter Gehalt an Rückständen oder unvorteilhaften Bestandteilen jeglicher Art oder bessere Verdaulichkeit, verbesserte Lagerstabilität des Erntegutes, verbesserter Toleranz gegenüber unvorteilhaften Temperaturen, verbesserter Toleranz gegenüber Dürre und Trockenheit, wie auch Sauerstoffmangel durch Wasserüberschuß, verbesserte Toleranz gegenüber erhöhten Salzgehalten in Böden und Wasser, gesteigerte  Shoot base diameter, increased leaf area, higher yields of nutrients and ingredients, e.g. Carbohydrates, fats, oils, proteins, vitamins, minerals, essential oils, dyes, fibers, better fiber quality, earlier flowering, increased number of flowers, reduced content of toxic products such as mycotoxins, reduced content of residues or unfavorable ingredients of any kind or better digestibility, improved Storage stability of the crop, improved tolerance to unfavorable temperatures, improved tolerance to drought and drought, as well as lack of oxygen due to excess water, improved tolerance to increased salt levels in soils and water, increased
Toleranz gegenüber Ozonstress, verbesserte Verträglichkeit gegenüber Herbiziden und anderen Pflanzenbehandlungsmitteln, verbesserte Wasseraufnahme und Tolerance to ozone stress, improved tolerance to herbicides and other plant treatment agents, improved water absorption and
Photosyntheseleistung, vorteilhafte Pflanzeneigenschaften, wie beispielsweise Beschleunigung der Reifung, gleichmäßigere Abreife, größere Anziehungskraft für Nützlinge, verbesserte Bestäubung oder andere Vorteile, die einem Fachmann durchaus bekannt sind. Photosynthetic performance, beneficial plant properties, such as acceleration of maturation, more uniform maturity, greater attraction for beneficials, improved pollination or other benefits that are well known to a person skilled in the art.
Insbesondere zeigt die erfindungsgemäße Verwendung einer oder mehrerer In particular, the use according to the invention shows one or more
Verbindungen der allgemeinen Formel (I) in der Sprühapplikation auf Pflanzen und Pflanzenteilen die beschriebenen Vorteile. Kombinationen von den Compounds of general formula (I) in the spray application to plants and parts of plants the advantages described. Combinations of the
erfindungsgemäßen substituierten l-(Arylethinyl)-, l-(Heteroarylethinyl)-, 1 -substituted l- (arylethynyl) -, l- (heteroarylethynyl) -, 1 -
(Heterocyclylethinyl)- und 1-(Cyloalkenylethinyl)-bicycloalkanolen der allgemeinen Formel (I) unter anderem mit Insektiziden, Lockstoffen, Akariziden, Fungiziden, Nematiziden, Herbiziden, wachstumsregulierenden Stoffen, Safenern, die (Heterocyclylethinyl) - and 1- (cycloalkenylethynyl) bicycloalkanols of general formula (I) inter alia with insecticides, attractants, acaricides, fungicides, nematicides, herbicides, growth regulators, safeners, the
Pflanzenreife beeinflussenden Stoffen und Bakteriziden können bei der Bekämpfung von Pflanzenkrankheiten und/oder zur Steigerung des Pflanzenertrags im Rahmen der vorliegenden Erfindung ebenfalls Anwendung finden. Die kombinierte Verwendung von erfindungsgemäßen substituierten l-(Arylethinyl)-, l-(Heteroarylethinyl)-, 1 - (Heterocyclylethinyl)- und 1-(Cyloalkenylethinyl)-bicycloalkanolen der allgemeinen Formel (I) mit gentechnisch veränderten Sorten in Bezug auf erhöhte abiotische Stresstoleranz ist darüber hinaus ebenfalls möglich. Plant-maturity influencing substances and bactericides can also find application in the control of plant diseases and / or to increase the plant yield in the context of the present invention. The combined use of substituted l- (arylethynyl) -, l- (heteroarylethynyl) -, 1- (heterocyclylethynyl) - and 1- (cycloalkenylethynyl) -bicycloalkanols of the general invention Moreover, formula (I) with genetically modified varieties in relation to increased abiotic stress tolerance is also possible.
Die weiter oben genannten verschiedenartigen Vorteile für Pflanzen lassen sich bekannterweise partiell zusammenfassen und mit allgemein gültigen Begriffen belegen. Soche Begriffe sind beispielsweise die nachfolgend aufgeführten The various advantages for plants mentioned above can, as is known, be partially summarized and substantiated by generally valid terms. Soche terms are, for example, those listed below
Bezeichnungen: phytotonischer Effekt, Widerstandsfähigkeit gegenüber Terms: phytotonic effect, resistance to
Stressfaktoren, weniger Pflanzenstress, Pflanzengesundheit, gesunde Pflanzen, Pflanzenfitness, („Plant Fitness"),„Plant Wellness",„Plant Concept",„Vigor Effect", „Stress Shield", Schutzschild,„Crop Health",„Crop Health Properties",„Crop Health Products",„Crop Health Management",„Crop Health Therapy",„Plant Health", Plant Health Properties", Plant Health Products",„Plant Health Management",„Plant Health Therapy", Grünungseffekt („Greening Effect" oder„Re-greening Effect"),„Freshness" oder andere Begriffe, die einem Fachmann durchaus bekannt sind. Stress Factors, Less Plant Stress, Plant Health, Healthy Plants, Plant Fitness, Plant Wellness, Plant Concept, Vigor Effect, Stress Shield, Shield, Crop Health, Crop Health Properties "Crop Health Products", "Crop Health Management", "Crop Health Therapy", "Plant Health", Plant Health Properties, "Plant Health Products", "Plant Health Management", "Plant Health Therapy", Greening Effect (" Greening effect "or" re-greening effect ")," Freshness "or other terms that are well known to a person skilled in the art.
Im Rahmen der vorliegenden Erfindung wird unter einem guten Effekt auf die In the present invention is under a good effect on the
Widerstandsfähigkeit gegenüber abiotischem Stress nicht beschränkend mindestens ein um im Allgemeinen 3 %, insbesondere größer als 5 % besonders bevorzugt größer als 10 % verbessertes Auflaufen, Resistance to abiotic stress not limiting at least one emergence improved by generally 3%, in particular greater than 5%, more preferably greater than 10%,
mindestens einen im Allgemeinen 3 %, insbesondere größer als 5 % besonders bevorzugt größer als 10 % gesteigerten Ertrag,  at least one generally 3%, in particular greater than 5%, particularly preferably greater than 10% increased yield,
mindestens eine um im Allgemeinen 3 %, insbesondere größer als 5 % besonders bevorzugt größer als 10 % verbesserte Wurzelentwicklung,  at least one root development generally improved by 3%, in particular greater than 5%, particularly preferably greater than 10%,
· mindestens eine um im Allgemeinen 3 %, insbesondere größer als 5 % besonders bevorzugt größer als 10 % ansteigende Sproßgröße, At least one shoot size increasing by generally 3%, in particular greater than 5%, particularly preferably greater than 10%,
mindestens eine um im Allgemeinen 3 %, insbesondere größer als 5 % besonders bevorzugt größer als 10 % vergrößerte Blattfläche,  at least one leaf area increased by generally 3%, in particular greater than 5%, particularly preferably greater than 10%,
mindestens eine um im Allgemeinen 3 %, insbesondere größer als 5 % besonders bevorzugt größer als 10 % verbesserte Photosyntheseleistung und/oder mindestens eine um im Allgemeinen 3 %, insbesondere größer als 5 % besonders bevorzugt größer als 10 % verbesserte Blütenausbildung verstanden, wobei die Effekte einzeln oder aber in beliebiger Kombination von zwei oder mehreren Effekten auftreten können. at least one photosynthesis performance improved by generally 3%, in particular greater than 5%, particularly preferably greater than 10%, and / or at least one improved flower formation by generally 3%, in particular greater than 5%, particularly preferably greater than 10% understood, the effects can occur individually or in any combination of two or more effects.
Weiterer Gegenstand der vorliegenden Erfindung ist eine Sprühlösung zur Behandlung von Pflanzen, enthaltend eine zur Steigerung der Widerstandsfähigkeit von Pflanzen gegenüber abioti sehen Stressfaktoren wirksame Menge von mindestens einer Another object of the present invention is a spray solution for the treatment of plants, containing an effective for increasing the resistance of plants to Abioti see stress factors amount of at least one
Verbindung aus der Gruppe der substituierten l -(Arylethinyl)-, 1 -(Heteroarylethinyl)-, 1- (Heterocyclylethinyl)- und 1-(Cyloalkenylethinyl)-bicycloalkanole der allgemeinen Formel (I). Die Sprühlösung kann andere übliche Bestandteile aufweisen, wie Compound selected from the group consisting of the substituted 1- (arylethynyl), 1- (heteroarylethynyl), 1- (heterocyclylethynyl) and 1- (cycloalkenylethynyl) -bicycloalkanols of the general formula (I). The spray solution may have other common ingredients, such as
Lösungsmittel, Formulierhilfsstoffe, insbesondere Wasser, enthalten. Weitere Solvents, formulation auxiliaries, especially water. Further
Bestandteile können unter anderem agrochemische Wirkstoffe sein, welche unten noch weiter beschrieben werden.  Ingredients may include, but are not limited to, agrochemical agents, which are further described below.
Weiterer Gegenstand der vorliegenden Erfindung ist die Verwendung von Another object of the present invention is the use of
entsprechenden Sprühlösungen zur Steigerung der Widerstandsfähigkeit von Pflanzen gegenüber abioti sehen Stressfaktoren. Die nachfolgenden Ausführungen gelten sowohl für die erfindungsgemäße Verwendung einer oder mehrerer Verbindungen der allgemeinen Formel (I) an sich als auch für die entsprechenden Sprühlösungen. Erfindunsgemäß wurde darüber hinaus gefunden, dass die Anwendung einer oder mehrerer Verbindungen der allgemeinen Formel (I) in Kombination mit mindestens einem Düngemittel wie weiter unten stehend definiert auf Pflanzen oder in deren Umgebung möglich ist. Düngemittel, die erfindungsgemäß zusammen mit den oben näher erläuterten erfindungsgemäßen Verbindungen der allgemeinen Formel (I) verwendet werden können, sind im Allgemeinen organische und anorganische Stickstoff-haltige corresponding spray solutions to increase the resistance of plants to abioti see stress factors. The following statements apply both to the inventive use of one or more compounds of general formula (I) per se and for the corresponding spray solutions. According to the invention, moreover, it has been found that the use of one or more compounds of general formula (I) in combination with at least one fertilizer as defined below is possible on plants or in their environment. Fertilizers which, according to the invention, can be used together with the compounds of the general formula (I) according to the invention which are explained in more detail above, are generally organic and inorganic nitrogen-containing
Verbindungen wie beispielsweise Harnstoffe, Harnstoff-Formaldehyd- Kondensationsprodukte, Aminosäuren, Ammoniumsalze und -nitrate, Kaliumsalze (bevorzugt Chloride, Sulfate, Nitrate), Phosphorsäuresalze und/oder Salze vonCompounds such as ureas, urea-formaldehyde condensation products, amino acids, ammonium salts and nitrates, potassium salts (preferably chlorides, sulfates, nitrates), phosphoric acid salts and / or salts of
Phosphoriger Säure (bevorzugt Kaliumsalze und Ammoniumsalze). Insbesondere zu nennen sind in diesem Zusammenhang die NPK-Dünger, d.h. Düngemittel, die Phosphoric acid (preferably potassium salts and ammonium salts). Particularly noteworthy in this connection are the NPK fertilizers, i. Fertilizers that
Stickstoff, Phosphor und Kalium enthalten, Kalkammonsalpeter, d.h. Düngemittel, die noch Calcium enthalten, Ammonsulfatsalpeter (Allgemeine Formel (NH4)2S04 NH4NO3), Ammonphosphat und Ammonsulfat. Diese Düngemittel sind dem Fachmann allgemein bekannt, siehe auch beispielsweise Ullmann's Encyclopedia of Industrial Chemistry, 5. Edition, Vol. A 10, Seiten 323 bis 431 , Verlagsgesellschaft, Weinheim, 1987. Nitrogen, phosphorus and potassium, calcium ammonium nitrate, ie fertilizers that still contain calcium, ammonium sulfate nitrate (general formula (NH 4 ) 2 SO 4 NH4NO3), ammonium phosphate and ammonium sulfate. These fertilizers are well known to those skilled in the art, see also, for example, Ullmann's Encyclopedia of Industrial Chemistry, 5th Edition, Vol. A 10, pages 323 to 431, Verlagsgesellschaft, Weinheim, 1987.
Die Düngemittel können auch Salze aus Mikronährstoffen (bevorzugt Calcium, Schwefel, Bor, Mangan, Magnesium, Eisen, Bor, Kupfer, Zink, Molybdän und Kobalt) und Phytohormonen (z. B. Vitamin B1 und Indol-(ll l)essigsäure) oder Gemische davon enthalten. Erfindungsgemäß eingesetzte Düngemittel können auch weitere Salze wie Monoammoniumphosphat (MAP), Diammoniumphosphat (DAP), Kaliumsulfat, The fertilizers may also contain salts of micronutrients (preferably calcium, sulfur, boron, manganese, magnesium, iron, boron, copper, zinc, molybdenum and cobalt) and phytohormones (eg, vitamin B1 and indole (II) acetic acid) or Mixtures thereof included. Fertilizers used according to the invention may also contain other salts such as monoammonium phosphate (MAP), diammonium phosphate (DAP), potassium sulfate,
Kaliumchlorid, Magnesiumsulfat enthalten. Geeignete Mengen für die sekundären Nährstoffe oder Spurenelemente sind Mengen von 0.5 bis 5 Gew.-%, bezogen auf das gesamte Düngemittel. Weitere mögliche Inhaltsstoffe sind Pflanzenschutzmittel, Insektizide oder Fungizide, Wachstumsregulatoren oder Gemische davon. Hierzu folgen weiter unten weitergehende Ausführungen. Containing potassium chloride, magnesium sulfate. Suitable amounts for the secondary nutrients or trace elements are amounts of 0.5 to 5 wt .-%, based on the total fertilizer. Further possible ingredients are crop protection agents, insecticides or fungicides, growth regulators or mixtures thereof. Further explanations follow below.
Die Düngemittel können beispielsweise in Form von Pulvern, Granulaten, Phils oder Kompaktaten eingesetzt werden. Die Düngemittel können jedoch auch in flüssiger Form, gelöst in einem wässrigen Medium, eingesetzt werden. In diesem Fall kann auch verdünnter wässriger Ammoniak als Stickstoffdüngemittel eingesetzt werden. Weitere mögliche Inhaltsstoffe für Düngemittel sind beispielsweise in Ullmann's Encyclopedia of Industrial Chemistry, 5. Auflage, 1987, Band A 10, Seiten 363 bis 401 , DE-A 41 28 828, DE-A 19 05 834 und DE-A 196 31 764 beschrieben. Die allgemeine Zusammensetzung der Düngemittel, bei welchen es sich im Rahmen der vorliegenden Erfindung um Einzelnährstoff- und/oder Mehrnährstoffdünger handeln kann, beispielsweise aus Stickstoff, Kalium oder Phosphor, kann innerhalb eines breiten Bereichs variieren. Im Allgemeinen ist ein Gehalt von 1 bis 30 Gew.-% Stickstoff (bevorzugt 5 bis 20 Gew.-%), von 1 bis 20 Gew.-% Kalium (bevorzugt 3 bis 15 Gew.- %) und ein Gehalt von 1 bis 20 Gew.-% Phosphor (bevorzugt 3 bis 10 Gew.-%) vorteilhaft. Der Gehalt von Mikroelementen ist üblicherweise im ppm-Bereich, bevorzugt im Bereich von von 1 bis 1000 ppm. The fertilizers can be used, for example, in the form of powders, granules, phils or compactates. However, the fertilizers can also be used in liquid form dissolved in an aqueous medium. In this case, dilute aqueous ammonia can be used as nitrogen fertilizer. Further possible ingredients for fertilizers are described, for example, in Ullmann's Encyclopedia of Industrial Chemistry, 5th Edition, 1987, Volume A 10, pages 363 to 401, DE-A 41 28 828, DE-A 19 05 834 and DE-A 196 31 764 , The general composition of the fertilizers, which in the context of the present invention may be single nutrient and / or multi-nutrient fertilizers, for example nitrogen, potassium or phosphorus, may vary within a wide range. In general, a content of 1 to 30 wt .-% of nitrogen (preferably 5 to 20 wt .-%), from 1 to 20 wt .-% potassium (preferably 3 to 15% by weight) and a content of 1 to 20% by weight of phosphorus (preferably 3 to 10% by weight) is advantageous. The content of microelements is usually in the ppm range, preferably in the range of from 1 to 1000 ppm.
Im Rahmen der vorliegenden Erfindung können das Düngemittel sowie eine oder mehrere erfindungsgemäße Verbindungen der allgemeinen Formel (I) zeitgleich verabreicht werden. Es ist jedoch auch möglich, zunächst das Düngemittel und dann eine oder mehrere erfindungsgemäße Verbindungen der allgemeinen Formel (I) oder zunächst eine oder mehrere Verbindungen der allgemeinen Formel (I) und dann das Düngemittel anzuwenden. Bei nicht zeitgleicher Anwendung einer oder mehrerer Verbindungen der allgemeinen Formel (I) und des Düngemittels erfolgt im Rahmen der vorliegenden Erfindung jedoch die Anwendung in funktionellem Zusammenhang, insbesondere innerhalb eines Zeitraums von im Allgemeinen 24 Stunden, bevorzugt 18 Stunden, besonders bevorzugt 12 Stunden, speziell 6 Stunden, noch spezieller 4 Stunden, noch weiter spezieller innerhalb 2 Stunden. In ganz besonderen In the context of the present invention, the fertilizer and one or more compounds of the general formula (I) according to the invention can be used simultaneously be administered. However, it is also possible first to apply the fertilizer and then one or more compounds of the general formula (I) according to the invention or first of all one or more compounds of the general formula (I) and then the fertilizer. In the case of non-simultaneous application of one or more compounds of the general formula (I) and of the fertilizer, however, the application is carried out in a functional context, especially within a period of generally 24 hours, preferably 18 hours, more preferably 12 hours, especially 6 hours, more specifically 4 hours, even more special within 2 hours. In a very special way
Ausführungsformen der vorliegenden Erfindung erfolgt die Anwendung einer oder mehrerer erfindungsgemäßer Verbindungen der Formel (I) und des Düngemittels in einem zeitlichen Rahmen von weniger als 1 Stunden, vorzugsweise weniger als 30 Minuten, besonders bevorzugt weniger als 15 Minuten. Bevorzugt ist die Verwendung von Verbindungen der allgemeinen Formel (I) auf Pflanzen aus der Gruppe der Nutzpflanzen, Zierpflanzen, Rasenarten, allgemein genutzte Bäume, die in öffentlichen und privaten Bereichen als Zierpflanzen Embodiments of the present invention use one or more compounds of the formula (I) and the fertilizer according to the invention in a time frame of less than 1 hour, preferably less than 30 minutes, more preferably less than 15 minutes. Preference is given to the use of compounds of the general formula (I) on plants from the group of crops, ornamental plants, lawn species, generally used trees, which are used in ornamental plants in public and private sectors
Verwendungen finden, und Forstbestand. Der Forstbestand umfasst Bäume für die Herstellung von Holz, Zellstoff, Papier und Produkten die aus Teilen der Bäume hergestellt werden. Der Begriff Nutzpflanzen, wie hier verwendet, bezeichnet Find uses, and forest stands. The forest stock includes trees for the production of wood, pulp, paper and products made from parts of the trees. The term crops as used herein refers to
Kulturpflanzen, die als Pflanzen für die Gewinnung von Nahrungsmitteln, Futtermitteln, Treibstoffe oder für technische Zwecke eingesetzt werden.  Crop plants used as plants for the production of food, feed, fuel or for technical purposes.
Zu den Nutzpflanzen zählen z. B. folgende Pflanzenarten: Triticale, Durum Among the useful plants include z. For example, the following plant species: Triticale, Durum
(Hartweizen), Turf, Reben, Getreide, beispielsweise Weizen, Gerste, Roggen, Hafer, Reis, Mais und Hirse; Rüben, beispielsweise Zuckerrüben und Futterrüben; Früchte, beispielsweise Kernobst, Steinobst und Beerenobst, beispielsweise Äpfel, Birnen, Pflaumen, Pfirsiche, Mandeln, Kirschen und Beeren, z. B. Erdbeeren, Himbeeren, Brombeeren; Hülsenfrüchte, beispielsweise Bohnen, Linsen, Erbsen und Sojabohnen; Ölkulturen, beispielsweise Raps, Senf, Mohn, Oliven, Sonnenblumen, Kokos, (Durum wheat), turf, vines, cereals, such as wheat, barley, rye, oats, rice, corn and millet; Beets, for example sugar beets and fodder beets; Fruits, such as pome fruit, stone fruit and soft fruit, such as apples, pears, plums, peaches, almonds, cherries and berries, eg. Strawberries, raspberries, blackberries; Legumes, such as beans, lentils, peas and soybeans; Oil crops, such as oilseed rape, mustard, poppy, olives, sunflowers, coconut,
Castorölpflanzen, Kakaobohnen und Erdnüsse; Gurkengewächse, beispielsweise Kürbis, Gurken und Melonen; Fasergewächse, beispielsweise Baumwolle, Flachs, Hanf und Jute; Citrusfrüchte, beispielsweise Orangen, Zitronen, Pampelmusen und Mandarinen; Gemüsesorten, beispielsweise Spinat, (Kopf)-Salat, Spargel, Kohlarten, Möhren, Zwiebeln, Tomaten, Kartoffeln und Paprika; Lorbeergewächse, beispielsweise Avocado, Cinnamomum, Kampfer, oder ebenso Pflanzen wie Tabak, Nüsse, Kaffee, Aubergine, Zuckerrohr, Tee, Pfeffer, Weinreben, Hopfen, Bananen, Castor oil plants, cocoa beans and peanuts; Cucurbits, for example squash, cucumbers and melons; Fiber plants, for example cotton, flax, hemp and jute; Citrus fruits, such as oranges, lemons, grapefruit and mandarins; Vegetables such as spinach, (head) salad, asparagus, cabbage, Carrots, onions, tomatoes, potatoes and peppers; Laurel family, such as avocado, cinnamomum, camphor, or plants such as tobacco, nuts, coffee, eggplant, sugar cane, tea, pepper, vines, hops, bananas,
Naturkautschukgewächse sowie Zierpflanzen, beispielsweise Blumen, Sträucher, Laubbäume und Nadelbäume wie Koniferen. Diese Aufzählung stellt keine Limitierung dar. Natural rubber plants and ornamental plants, such as flowers, shrubs, deciduous trees and conifers such as conifers. This list is not a limitation.
Als besonders geeignete Zielkulturen für die Anwendung des erfindungsgemäßen Verfahrens sind folgende Pflanzen anzusehen: Hafer, Roggen, Triticale, Durum, Baumwolle, Aubergine, Turf, Kernobst, Steinobst, Beerenobst, Mais, Weizen, Gerste, Gurke, Tabak, Reben, Reis, Getreide, Birne, Pfeffer, Bohnen, Sojabohnen, Raps, Tomate, Paprika, Melonen, Kohl, Kartoffel und Apfel. Particularly suitable target crops for the application of the method according to the invention are the following plants: oats, rye, triticale, durum, cotton, aubergine, turf, pome fruit, stone fruit, berry fruit, corn, wheat, barley, cucumber, tobacco, vines, rice, cereals , Pear, pepper, beans, soybeans, rape, tomato, paprika, melons, cabbage, potato and apple.
Als Bäume, die entsprechend dem erfindungsgemäßen Verfahren verbessert werden können, seien beispielhaft genannt: Abies sp., Eucalyptus sp., Picea sp., Pinus sp., Aesculus sp., Platanus sp., Tilia sp., Acer sp., Tsuga sp., Fraxinus sp., Sorbus sp., Betula sp., Crataegus sp., Ulmus sp., Quercus sp., Fagus sp., Salix sp., Populus sp.. Examples of trees which can be improved according to the method of the invention are: Abies sp., Eucalyptus sp., Picea sp., Pinus sp., Aesculus sp., Platanus sp., Tilia sp., Acer sp., Tsuga sp , Fraxinus sp., Sorbus sp., Betula sp., Crataegus sp., Ulmus sp., Quercus sp., Fagus sp., Salix sp., Populus sp.
Als bevorzugte Bäume, die entsprechend dem erfindungsgemäßen Verfahren verbessert werden können, können genannt werden: Aus der Baumart Aesculus: A. hippocastanum, A. pariflora, A. carnea; aus der Baumart Platanus: P. aceriflora, P. occidentalis, P. racemosa; aus der Baumart Picea: P. abies; aus der Baumart Pinus:As preferred trees, which can be improved according to the method of the invention, may be mentioned: From the tree species Aesculus: A. hippocastanum, A. pariflora, A. carnea; from the tree species Platanus: P. aceriflora, P. occidentalis, P. racemosa; from the tree species Picea: P. abies; from the tree species Pinus:
P. radiate, P. ponderosa, P. contorta, P. sylvestre, P. elliottii, P. montecola, P. P. radiate, P. ponderosa, P. contorta, P. sylvestre, P. elliottii, P. montecola, P.
albicaulis, P. resinosa, P. palustris, P. taeda, P. flexilis, P. jeffregi, P. baksiana, P. strobes; aus der Baumart Eucalyptus: E. grandis, E. globulus, E. camadentis, E. albicaulis, P. resinosa, P. palustris, P. taeda, P. flexilis, P. jeffregi, P. baksiana, P. strobes; from the tree species Eucalyptus: E. grandis, E. globulus, E. camadentis, E.
nitens, E. obliqua, E. regnans, E. pilularus. nitens, E. obliqua, E. regnans, E. pilularus.
Als besonders bevorzugte Bäume, die entsprechend dem erfindungsgemäßen Verfahren verbessert werden können, können genannt werden: Aus der Baumart Pinus: P. radiate, P. ponderosa, P. contorta, P. sylvestre, P. strobes; aus der Baumart Eucalyptus: E. grandis, E. globulus und E. camadentis. Als besonders bevorzugte Bäume, die entsprechend dem erfindungsgemäßen As particularly preferred trees, which can be improved according to the method of the invention, may be mentioned: From the species Pinus: P. radiate, P. ponderosa, P. contorta, P. sylvestre, P. strobes; from the tree species Eucalyptus: E. grandis, E. globulus and E. camadentis. As particularly preferred trees, according to the invention
Verfahren verbessert werden können, können genannt werden: Rosskastanie, Platanengewächs, Linde und Ahornbaum. Die vorliegende Erfindung kann auch an beliebigen Rasenarten („turfgrasses") durchgeführt werden, einschließlich„cool season turfgrasses" und„warm season turfgrasses". Beispiele für Rasenarten für die kalte Jahreszeit sind Blaugräser („blue grasses"; Poa spp.), wie„Kentucky bluegrass" (Poa pratensis L),„rough bluegrass" (Poa trivialis L),„Canada bluegrass" (Poa compressa L),„annual bluegrass" (Poa annua L),„upland bluegrass" (Poa glaucantha Gaudin),„wood bluegrass" (Poa nemoralis L.) und„bulbous bluegrass" (Poa bulbosa L); Straussgräser („Bentgrass", Agrostis spp.), wie„creeping bentgrass" (Agrostis palustris Huds.),„coloniai bentgrass" (Agrostis tenuis Sibth.),„velvet bentgrass" (Agrostis canina L),„South German Mixed Bentgrass" (Agrostis spp. einschließlich Agrostis tenius Sibth., Agrostis canina L, und Agrostis palustris Huds.), und„redtop" (Agrostis alba L); Procedures that can be improved include: horse chestnut, sycamore, linden and maple tree. The present invention may also be practiced on any turfgrasses, including "cool season turfgrasses" and "warm season turfgrasses." Examples of cold season turf species are blue grasses (Poa spp.), Such as "Kentucky bluegrass" (Poa pratensis L), "rough bluegrass" (Poa trivialis L), "Canada bluegrass" (Poa compressa L), "annual bluegrass" (Poa annua L), "upland bluegrass" (Poa glaucantha Gaudin), "Wood bluegrass" (Poa nemoralis L.) and "bulbous bluegrass" (Poa bulbosa L); ostrich grasses ("Bentgrass", Agrostis spp.), Such as "creeping bentgrass" (Agrostis palustris Huds.), "Coloniai bentgrass" (Agrostis Tenuis Sibth.), "velvet bentgrass" (Agrostis canina L), "South German Mixed Bentgrass" (Agrostis spp., including Agrostis tenius Sibth., Agrostis canina L, and Agrostis palustris Huds.), and "redtop" (Agrostis alba L );
Schwingel („Fescues", Festucu spp.), wie„red fescue" (Festuca rubra L. spp. rubra), „creeping fescue" (Festuca rubra L),„chewings fescue" (Festuca rubra commutata Gaud.),„sheep fescue" (Festuca ovina L),„hard fescue" (Festuca longifolia Thuill.), „hair fescue" (Festucu capillata Lam.),„tall fescue" (Festuca arundinacea Schreb.) und „meadow fescue" (Festuca elanor L.); Fescue ("Fescues", Festucu spp.), Such as "red fescue" (Festuca rubra L. spp. Rubra), "creeping fescue" (Festuca rubra L), "chewings fescue" (Festuca rubra commutata Gaud.), "Sheep fescue "(Festuca ovina L)," hard fescue "(Festuca longifolia Thuill.)," hair fescue "(Festucu capillata Lam.)," tall fescue "(Festuca arundinacea Schreb.) and" meadow fescue "(Festuca elanor L. );
Lolch („ryegrasses", Lolium spp.), wie„annual ryegrass" (Lolium multifiorum Lam.), „perennial ryegrass" (Lolium perenne L.) und„italian ryegrass" (Lolium multifiorum Lam.); und Weizengräser ("wheatgrasses", Agropyron spp..), wie "fairway wheatgrass" (Agropyron cristatum (L.) Gaertn.),„crested wheatgrass" (Agropyron desertorum (Fisch.) Schult.) und "western wheatgrass" (Agropyron smithii Rydb.). Lolium ("ryegrasses", Lolium spp.), Such as "annual ryegrass" (Lolium multifiorum Lam.), "Perennial ryegrass" (Lolium perenne L.) and "Italian ryegrass" (Lolium multifiorum Lam.); and wheat grasses ("wheatgrasses", Agropyron spp.), such as "fairway wheatgrass" (Agropyron cristatum (L.) Gaertn.), "crested wheatgrass" (Agropyron desertorum (fish.) Schult.) and "western wheatgrass" (Agropyron smithii Rydb.).
Beispiele für weitere "cool season turfgrasses" sind "beachgrass" (Ammophila breviligulata Fern.), "smooth bromegrass" (Bromus inermis Leyss.), Schilf ("cattails") wie "Timothy" (Phleum pratense L.), "sand cattail" (Phleum subulatum L.), "orchardgrass" (Dactylis glomerata L), "weeping alkaligrass" (Puccinellia distans (L.) Pari.) und "crested dog's-tail" (Cynosurus cristatus L.). Examples of other "cool season turfgrasses" are "beachgrass" (Ammophila breviligulata Fern.), "Smooth bromegrass" (Bromus inermis leyss.), Reeds ("cattails") such as "Timothy" (Phleum pratense L.), "sand cattail "(Phleum subulatum L.) "orchardgrass" (Dactylis glomerata L), "weeping alkaligrass" (Puccinellia distans (L.) Pari.) and "crested dog's-tail" (Cynosurus cristatus L.).
Beispiele für "warm season turfgrasses" sind„Bermudagrass" (Cynodon spp. L. C. Rieh), "zoysiagrass" (Zoysia spp. Willd.),„St. Augustine grass" (Stenotaphrum secundatum Walt Kuntze),„centipedegrass" (Eremochloa ophiuroides Munro Hack.), „carpetgrass" (Axonopus affinis Chase),„Bahia grass" (Paspalum notatum Flügge), „Kikuyugrass" (Pennisetum clandestinum Höchst, ex Chiov.),„buffalo grass" (Buchloe daetyloids (Nutt.) Engelm.), "Blue gramma" (Bouteloua gracilis (H.B.K.) Lag. ex Griffiths),„seashore paspalum" (Paspalum vaginatum Swartz) und„sideoats grama" (Bouteloua curtipendula (Michx. Torr.). "Cool season turfgrasses" sind für die erfindungsgemäße Verwendung im Allgemeinen bevorzugt. Besonders bevorzugt sind Blaugras, Straussgras und„redtop", Schwingel und Lolch. Straussgras ist Examples of "warm season turfgrasses" are "Bermudagrass" (Cynodon spp., LC Rieh), "zoysiagrass" (Zoysia spp. Willd.), "St. Augustine grass" (Stenotaphrum secundatum Walt Kuntze), "centipedegrass" (Eremochloa ophiuroides Munro Hack.), "Carpetgrass" (Axonopus affinis chase), "Bahia grass" (Paspalum notatum flügge), "Kikuyugrass" (Pennisetum clandestinum Höchst, ex Chiov.), "Buffalo grass" (Buchloe daetyloids (Nutt.) Engelm.) , "Blue gramma" (Bouteloua gracilis (HBK) lag. Ex Griffiths), "seashore paspalum" (Paspalum vaginatum Swartz) and "sideoats grama" (Bouteloua curtipendula (Michx. Torr.). "Cool season turfgrasses" are for the present invention Use is generally preferred Bleach grass, ostrich grass and "redtop", fescue and lolk are particularly preferred
insbesondere bevorzugt. especially preferred.
Besonders bevorzugt werden mit den erfindungsgemäßen Verbindungen der allgemeinen Formel (I) Pflanzen der jeweils handelsüblichen oder in Gebrauch befindlichen Pflanzensorten behandelt. Unter Pflanzensorten versteht man Pflanzen mit neuen Eigenschaften ("Traits"), die sowohl durch konventionelle Züchtung, durch M utagenese oder mit Hilfe rekombinanter DNA-Techniken, gezüchtet worden sind. Kulturpflanzen können demnach Pflanzen sein, die durch konventionelle Züchtungsund Optimierungsmethoden oder durch biotechnologische und gentechnologische Methoden oder Kombinationen dieser Methoden erhalten werden können, einschließlich der transgenen Pflanzen und einschließlich der durch Sortenschutzrechte schützbaren oder nicht schützbaren Pflanzensorten. Particular preference is given to treating the compounds of the general formula (I) according to the invention with plants of the respective commercially available or used plant cultivars. Plant varieties are understood as meaning plants with new traits that have been bred either by conventional breeding, by matagenesis or by recombinant DNA techniques. Crop plants can accordingly be plants which can be obtained by conventional breeding and optimization methods or by biotechnological and genetic engineering methods or combinations of these methods, including the transgenic plants and including the plant varieties which can or can not be protected by plant breeders' rights.
Das erfindungsgemäße Behandlungsverfahren kann somit auch für die Behandlung von genetisch modifizierten Organismen (GMOs), z. B. Pflanzen oder Samen, verwendet werden. Genetisch modifizierte Pflanzen (oder transgene Pflanzen) sind Pflanzen, bei denen ein heteroioges Gen stabil in das Genom integriert worden ist. Der Begriff "heteroioges Gen" bedeutet im wesentlichen ein Gen, das außerhalb der Pflanze bereitgestellt oder assembliert wird und das bei Einführung in das The treatment method according to the invention can thus also for the treatment of genetically modified organisms (GMOs), z. As plants or seeds are used. Genetically modified plants (or transgenic plants) are plants in which a heteroiogous gene has been stably integrated into the genome. The term "hetero gene gene" essentially means a gene that is provided or assembled outside the plant and that when introduced into the plant
Zellkerngenom, das Chloroplastengenom oder das Hypochondriengenom der transformierten Pflanze dadurch neue oder verbesserte agronomische oder sonstige Eigenschaften verleiht, dass es ein interessierendes Protein oder Polypeptid exprimiert oder dasses ein anderes Gen, das in der Pflanze vorliegt bzw. andere Gene, die in der Pflanze vorliegen, herunterreguliert oder abschaltet (zum Beispiel mittels Antisense- Technologie, Co-suppressionstechnologie oder NAi-Technologie [RNA Interference]). Ein heterologes Gen, das im Genom vorliegt, wird ebenfalls als Transgen bezeichnet. Ein Transgen, das durch sein spezifisches Vorliegen im Pflanzengenom definiert ist, wird als Transformations- bzw. transgenes Event bezeichnet. Nuclear genome, the chloroplast genome or the hypochondria genome of the transformed plant thereby new or improved agronomic or otherwise Lends properties that it expresses a protein or polypeptide of interest or that it downregulates or shuts down another gene present in the plant or other genes present in the plant (for example, by antisense technology, co-suppression technology or Technology [RNA Interference]). A heterologous gene present in the genome is also referred to as a transgene. A transgene defined by its specific presence in the plant genome is referred to as a transformation or transgenic event.
Zu Pflanzen und Pflanzensorten, die vorzugsweise mit den erfindungsgemäßen Verbindungen der allgemeinen Formel (I) behandelt werden, zählen alle Pflanzen, die über Erbgut verfügen, das diesen Pflanzen besonders vorteilhafte, nützliche Merkmale verleiht (egal, ob dies durch Züchtung und/oder Biotechnologie erzielt wurde). Plants and plant varieties which are preferably treated with the compounds of the general formula (I) according to the invention include all plants which have genetic material which gives these plants particularly advantageous, useful features (regardless of whether this is achieved by breeding and / or biotechnology has been).
Pflanzen und Pflanzensorten, die ebenfalls mit den erfindungsgemäßen Verbindungen der allgemeinen Formel (I) behandelt werden können, sind solche Pflanzen, die gegen einen oder mehrere abiotische Streßfaktoren resistent sind. Zu den abioti sehen Streßbedingungen können zum Beispiel Hitze, Dürre, Kälte- und Trockenstress,, osmotischer Streß, Staunässe, erhöhter Bodensalzgehalt, erhöhtes Ausgesetztsein an Mineralien, Ozonbedingungen, Starklichtbedingungen, beschränkte Verfügbarkeit von Stickstoffnährstoffen, beschränkte Verfügbarkeit von Phosphornährstoffen oder Vermeidung von Schatten zählen. Plants and plant varieties which can also be treated with the compounds of the general formula (I) according to the invention are those plants which are resistant to one or more abiotic stress factors. Abiotic stress conditions may include, for example, heat, drought, cold and dry stress, osmotic stress, waterlogging, increased soil salt content, increased exposure to minerals, ozone conditions, high light conditions, limited availability of nitrogen nutrients, limited availability of phosphorous nutrients, or avoidance of shade.
Pflanzen und Pflanzensorten, die ebenfalls mit den erfindungsgemäßen Verbindungen der allgemeinen Formel (I) behandelt werden können, sind solche Pflanzen, die durch erhöhte Ertragseigenschaften gekennzeichnet sind. Ein erhöhter Ertrag kann bei diesen Pflanzen z. B. auf verbesserter Pflanzenphysiologie, verbessertem Plants and plant varieties which can also be treated with the compounds of the general formula (I) according to the invention are those plants which are characterized by increased yield properties. An increased yield can in these plants z. B. on improved plant physiology, improved
Pflanzenwuchs und verbesserter Pflanzenentwicklung, wie Plant growth and improved plant development, such as
Wasserverwertungseffizienz, Wasserhalteeffizienz, verbesserter Stickstoffverwertung, erhöhter Kohlenstoffassimilation, verbesserter Photosynthese, verstärkter Keimkraft und beschleunigter Abreife beruhen. Der Ertrag kann weiterhin durch eine verbesserte Pfianzenarchitektur (unter Streß- und nicht-Streß-Bedingungen) beeinflußt werden, darunter frühe Blüte, Kontrolle der Blüte für die Produktion von Hybridsaatgut,  Water utilization efficiency, water retention efficiency, improved nitrogen utilization, increased carbon assimilation, improved photosynthesis, increased germination power and accelerated Abreife based. The yield may be further influenced by improved plant architecture (under stress and non-stress conditions), including early flowering, control of flowering for the production of hybrid seed,
Keimpflanzenwüchsigkeit, Pflanzengröße, Internodienzahl und -abstand, Seedling vigor, plant size, internode count and distance,
Wurzelwachstum, Samengröße, Fruchtgröße, Schotengröße, Schoten- oder Ährenzahl, Anzahl der Samen pro Schote oder Ähre, Samenmasse, verstärkte Root growth, seed size, fruit size, pod size, pods or Ear number, number of seeds per pod or ear, seed mass, strengthened
Samenfüllung, verringerter Samenausfall, verringertes Schotenplatzen sowie Seed filling, reduced seed failure, reduced pod popping as well
Standfestigkeit. Zu weiteren Ertragsmerkmalen zählen Samenzusammensetzung wie Kohlenhydratgehalt, Proteingehalt, ölgehalt und ölzusammensetzung, Nährwert, Verringerung der nährwidrigen Verbindungen, verbesserte Verarbeitbarkeit und verbesserte Lagerfähigkeit. Stability. Other yield-related traits include seed composition such as carbohydrate content, protein content, oil content and oil composition, nutritional value, reduction in nontoxic compounds, improved processability, and improved shelf life.
Pflanzen, die ebenfalls mit den erfindungsgemäßen Verbindungen der allgemeinen Formel (I) behandelt werden können, sind Hybridpflanzen, die bereits die Plants which can also be treated with the compounds of the general formula (I) according to the invention are hybrid plants which have already been used
Eigenschaften der Heterosis bzw. des Hybrideffekts exprimieren, was im allgemeinen zu höherem Ertrag, höherer Wüchsigkeit, besserer Gesundheit und besserer Characteristics of heterosis or hybrid effect, which generally results in higher yield, higher vigor, better health and better
Resistenz gegen biotische und abiotische Streßfaktoren führt. Solche Pflanzen werden typischerweise dadurch erzeugt, dass man eine ingezüchtete pollensterile Elternlinie (den weiblichen Kreuzungspartner) mit einer anderen ingezüchteten pollenfertilen Elternlinie (dem männlichen Kreuzungspartner) kreuzt. Das Hybridsaatgut wird typischerweise von den pollensterilen Pflanzen geerntet und an Vermehrer verkauft. Pollensterile Pflanzen können manchmal (z. B. beim Mais) durch Entfahnen (d. h. mechanischem Entfernen der männlichen Geschlechtsorgane bzw. der männlichen Blüten), produziert werden; es ist jedoch üblicher, dass die Pollensterilität auf genetischen Determinanten im Pflanzengenom beruht. In diesem Fall, insbesondere dann, wenn es sich bei dem gewünschten Produkt, da man von den Hybridpflanzen ernten will, um die Samen handelt, ist es üblicherweise günstig, sicherzustellen, dass die Pollenfertilität in Hybridpflanzen, die die für die Pollensterilität verantwortlichen genetischen Determinanten enthalten, völlig restoriert wird. Dies kann erreicht werden, indem sichergestellt wird, dass die männlichen Kreuzungspartner entsprechende Fertilitätsrestorergene besitzen, die in der Lage sind, die Pollenfertilität in Resistance to biotic and abiotic stress factors leads. Such plants are typically produced by crossing an inbred male sterile parental line (the female crossover partner) with another inbred male fertile parent line (the male crossbred partner). The hybrid seed is typically harvested from the male sterile plants and sold to propagators. Pollen sterile plants can sometimes be produced (eg in maize) by delaving (i.e., mechanically removing male genitalia or male flowers); however, it is more common for male sterility to be due to genetic determinants in the plant genome. In this case, especially when the desired product, as one wants to harvest from the hybrid plants, is the seeds, it is usually beneficial to ensure that the pollen fertility in hybrid plants containing the genetic determinants responsible for male sterility , completely restored. This can be accomplished by ensuring that the male crossbred partners possess appropriate fertility restorer genes capable of controlling pollen fertility in humans
Hybridpflanzen, die die genetischen Determinanten, die für die Pollensterilität verantwortlich sind, enthalten, zu restorieren. Genetische Determinanten für Hybrid plants that contain the genetic determinants responsible for male sterility. Genetic determinants for
Pollensterilität können im Cytoplasma lokalisiert sein. Beispiele für cytoplasmatische Pollensterilität (CMS) wurden zum Beispiel für Brassica-Arten beschrieben Pollen sterility may be localized in the cytoplasm. Examples of cytoplasmic male sterility (CMS) have been described, for example, for Brassica species
(WO 92/005251 . WO 95/009910, WO 98/27806, WO 05/002324, WO 06/021972 und US 6,229,072). Genetische Determinanten für Pollensterilität können jedoch auch im Zellkerngenom lokalisiert sein. Pollensterile Pflanzen können auch mit Methoden der pflanzlichen Biotechnologie, wie Gentechnik, erhalten werden. Ein besonders günstiges Mittel zur Erzeugung von pollensterilen Pflanzen ist in WO 89/10396 beschrieben, wobei zum Beispiel eine Ribonuklease wie eine Barnase selektiv in den Tapetumzellen in den Staubblättern exprimiert wird. Die Fertilität kann dann durch Expression eines Ribonukleasehemmers wie Barstar in den Tapetumzellen restoriert werden (z. B. WO 91 /002069). (WO 92/005251, WO 95/009910, WO 98/27806, WO 05/002324, WO 06/021972 and US 6,229,072). However, genetic determinants of pollen sterility may also be localized in the nuclear genome. Pollen sterile plants can also be obtained using plant biotechnology methods such as genetic engineering. A special A convenient means of producing male sterile plants is described in WO 89/10396, wherein, for example, a ribonuclease such as a barnase is selectively expressed in the tapetum cells in the stamens. The fertility can then be restorated by expression of a ribonuclease inhibitor such as barstar in the tapetum cells (eg WO 91/002069).
Pflanzen oder Pflanzensorten (die mit Methoden der Pflanzenbiotechnologie, wie der Gentechnik, erhalten werden), die ebenfalls mit den erfindungsgemäßen Plants or plant varieties (which are obtained by plant biotechnology methods, such as genetic engineering), which also with the inventive
Verbindungen der allgemeinen Formel (I) behandelt werden können, sind Compounds of general formula (I) can be treated are
herbizidtolerante Pflanzen, d. h. Pflanzen, die gegenüber einem oder mehreren vorgegebenen Herbiziden tolerant gemacht worden sind. Solche Pflanzen können entweder durch genetische Transformation oder durch Selektion von Pflanzen, die eine Mutation enthalten, die solch eine Herbizidtoleranz verleiht, erhalten werden. Herbizidtolerante Pflanzen sind zum Beispiel glyphosatetolerante Pflanzen, d. h. herbicide-tolerant plants, d. H. Plants tolerant to one or more given herbicides. Such plants can be obtained either by genetic transformation or by selection of plants containing a mutation conferring such herbicide tolerance. Herbicide-tolerant plants are, for example, glyphosate-tolerant plants, i. H.
Pflanzen, die gegenüber dem Herbizid Glyphosate oder dessen Salzen tolerant gemacht worden sind. So können zum Beispiel glyphosatetolerante Pflanzen durch Transformation der Pflanze mit einem Gen, das für das Enzym 5-Enolpyruvylshikimat- 3-phosphatsynthase (EPSPS) kodiert, erhalten werden. Beispiele für solche EPSPS- Gene sind das AroA-Gen (Mutante CT7) des Bakterium Salmonella typhimurium (Comai et al., Science (1983), 221 , 370-371 ), das CP4-Gen des Bakteriums Plants tolerant to the herbicide glyphosate or its salts. For example, glyphosate-tolerant plants can be obtained by transforming the plant with a gene encoding the enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS). Examples of such EPSPS genes are the AroA gene (mutant CT7) of the bacterium Salmonella typhimurium (Comai et al., Science (1983), 221, 370-371), the CP4 gene of the bacterium
Agrobacterium sp. (Barry et al., Curr. Topics Plant Physiol. (1992), 7, 139-145), die Gene, die für eine EPSPS aus der Petunie (Shah et al., Science (1986), 233, 478- 481 ), für eine EPSPS aus der Tomate (Gasser et al., J. Biol. Chem. (1988), 263, 4280- 4289) oder für eine EPSPS aus Eieusine (WO 01/66704) kodieren. Es kann sich auch um eine mutierte EPSPS handeln, wie sie zum Beispiel in EP-A 0837944, Agrobacterium sp. (Barry et al., Curr Topics Plant Physiol. (1992), 7, 139-145), the genes responsible for petunia EPSPS (Shah et al., Science (1986), 233, 478-481). , for an EPSPS from the tomato (Gasser et al., J. Biol. Chem. (1988), 263, 4280- 4289) or for EPSPS from Eieusine (WO 01/66704) encode. It may also be a mutated EPSPS, as described, for example, in EP-A 0837944,
WO 00/066746, WO 00/066747 oder WO 02/026995 beschrieben ist. WO 00/066746, WO 00/066747 or WO 02/026995.
Glyphosatetolerante Pflanzen können auch dadurch erhalten werden, dass man ein Gen exprimiert, das für ein Glyphosate-Oxidoreduktase-Enzym, wie es in US Glyphosate-tolerant plants can also be obtained by expressing a gene encoding a glyphosate oxidoreductase enzyme as described in US Pat
5,776,760 und US 5,463,175 beschrieben ist, kodiert. Glyphosatetolerante Pflanzen können auch dadurch erhalten werden, dass man ein Gen exprimiert, das für ein Glyphosate-acetyltransferase-Enzym, wie es in z. B. WO 02/036782, WO 03/092360, WO 05/012515 und WO 07/024782 beschrieben ist, kodiert. Glyphosatetolerante Pflanzen können auch dadurch erhalten werden, dass man Pflanzen, die natürlich vorkommende Mutationen der oben erwähnten Gene, wie sie zum Beispiel in WO 01/024615 oder WO 03/013226 beschrieben sind, enthalten, selektiert. 5,776,760 and US 5,463,175. Glyphosate-tolerant plants can also be obtained by expressing a gene encoding a glyphosate acetyltransferase enzyme as described in e.g. WO 02/036782, WO 03/092360, WO 05/012515 and WO 07/024782. Glyphosate-tolerant plants can also be obtained by using plants that are natural occurring mutations of the above-mentioned genes, as described for example in WO 01/024615 or WO 03/013226, selected.
Sonstige herbizidresistente Pflanzen sind zum Beispiel Pflanzen, die gegenüber Herbiziden, die das Enzym Glutaminsynthase hemmen, wie Bialaphos, Phosphinotricin oder Glufosinate, tolerant gemacht worden sind. Solche Pflanzen können dadurch erhalten werden, dass man ein Enzym exprimiert, das das Herbizid oder eine Mutante des Enzyms Glutaminsynthase, das gegenüber Hemmung resistent ist, entgiftet. Solch ein wirksames entgiftendes Enzym ist zum Beispiel ein Enzym, das für ein Other herbicide-resistant plants are, for example, plants which have been tolerated to herbicides which inhibit the enzyme glutamine synthase, such as bialaphos, phosphinotricin or glufosinate. Such plants can be obtained by expressing an enzyme which detoxifies the herbicide or a mutant of the enzyme glutamine synthase, which is resistant to inhibition. Such an effective detoxifying enzyme is, for example, an enzyme suitable for
Phosphinotricin-acetyltransferase kodiert (wie zum Beispiel das bar- oder pat-Protein aus Streptomyces-Arten). Pflanzen, die eine exogene Phosphinotricin- acetyltransferase exprimieren, sind zum Beispiel in US 5,561 ,236; US 5,648,477; Phosphinotricin acetyltransferase encoded (such as the bar or pat protein from Streptomyces species). Plants expressing an exogenous phosphinotricin acetyltransferase are described, for example, in US 5,561,236; US 5,648,477;
US 5.646.024; US 5,273,894; US 5,637,489; US 5.276.268; US 5,739.082; US US 5,646,024; US 5,273,894; US 5,637,489; US 5,276,268; US 5,739,082; US
5.908,810 und US 7,1 12,665 beschrieben. 5,908,810 and US 7,112,665.
Weitere herbizidtolerante Pflanzen sind auch Pflanzen, die gegenüber den Herbiziden, die das Enzym Hydroxyphenylpyruvatdioxygenase (HPPD) hemmen, tolerant gemacht worden sind. Bei den Hydroxyphenylpyruvatdioxygenasen handelt es sich um Enzyme, die die Reaktion, in der para-Hydroxyphenylpyruvat (HPP) zu Homogentisat umgesetzt wird, katalysieren. Pflanzen, die gegenüber HPPD-Hemmern tolerant sind, können mit einem Gen, das für ein natürlich vorkommendes resistentes HPPD-Enzym kodiert, oder einem Gen, das für ein mutiertes HPPD-Enzym gemäß WO 96/038567, Further herbicide-tolerant plants are also plants tolerant to the herbicides which inhibit the enzyme hydroxyphenylpyruvate dioxygenase (HPPD). The hydroxyphenylpyruvate dioxygenases are enzymes that catalyze the reaction in which para-hydroxyphenylpyruvate (HPP) is converted to homogentisate. Plants tolerant to HPPD inhibitors may be treated with a gene encoding a naturally occurring resistant HPPD enzyme, or a gene encoding a mutant HPPD enzyme according to WO 96/038567,
WO 99/024585 und WO 99/024586 kodiert, transformiert werden. Eine Toleranz gegenüber HPPD-Hemmern kann auch dadurch erzielt werden, dass man Pflanzen mit Genen transformiert, die für gewisse Enzyme kodieren, die die Bildung von WO 99/024585 and WO 99/024586. Tolerance to HPPD inhibitors can also be achieved by transforming plants with genes encoding certain enzymes that promote the formation of HPPD inhibitors
Homogentisat trotz Hemmung des nativen HPPD-Enzyms durch den HPPD-Hemmer ermöglichen. Solche Pflanzen und Gene sind in WO 99/034008 und WO 2002/36787 beschrieben. Die Toleranz von Pflanzen gegenüber HPPD-Hemmern kann auch dadurch verbessert werden, dass man Pflanzen zusätzlich zu einem Gen, das für ein HPPD-tolerantes Enzym kodiert, mit einem Gen transformiert, das für ein  Allow homogentisate despite inhibition of the native HPPD enzyme by the HPPD inhibitor. Such plants and genes are described in WO 99/034008 and WO 2002/36787. The tolerance of plants to HPPD inhibitors can also be improved by transforming plants with a gene coding for an HPPD-tolerant enzyme in addition to a gene encoding a HPPD-tolerant enzyme
Prephenatdehydrogenase-Enzym kodiert, wie dies in WO 2004/024928 beschrieben ist. Weitere herbizidresistente Pflanzen sind Pflanzen, die gegenüber Acetolactatsynthase (ALS)-Hemmern tolerant gemacht worden sind. Zu bekannten ALS-Hemmern zählen zum Beispiel Sulfonylharnstoff, Imidazolinon, Triazolopyrimidine, Prephenate dehydrogenase enzyme encodes, as described in WO 2004/024928. Other herbicide-resistant plants are plants that have been tolerated to acetolactate synthase (ALS) inhibitors. Examples of known ALS inhibitors include sulfonylurea, imidazolinone, triazolopyrimidines,
Pyrimidinyloxy(thio)benzoate und/oder Sulfonylaminocarbonyltriazolinon-Herbizide. Es ist bekannt, dass verschiedene Mutationen im Enzym ALS (auch als Pyrimidinyloxy (thio) benzoates and / or sulfonylaminocarbonyltriazolinone herbicides. It is known that various mutations in the enzyme ALS (also known as
Acetohydroxysäure-Synthase, AHAS, bekannt) eine Toleranz gegenüber Acetohydroxy acid synthase, AHAS, known) a tolerance to
unterschiedlichen Herbiziden bzw. Gruppen von Herbiziden verleihen, wie dies zum Beispiel bei Tranel und Wright, Weed Science (2002), 50, 700-712, jedoch auch in US 5.605.01 1 , US 5,378,824, US 5.141 ,870 und US 5.013,659, beschrieben ist. Die Herstellung von sulfonylharnstofftoleranten Pflanzen und imidazolinontoleranten Pflanzen ist in US 5,605,01 1 ; US 5,013,659; US 5.141 ,870; US 5,767.361 ; US different herbicides or groups of herbicides, as described, for example, by Tranel and Wright, Weed Science (2002), 50, 700-712, but also in US 5,605,011, US 5,378,824, US 5,141,870 and US 5,013, 659, is described. The preparation of sulfonylurea tolerant plants and imidazolinone tolerant plants is described in US 5,605,011 1; US 5,013,659; US 5,141,870; US 5,767,361; US
5,731 ,180; US 5,304,732; US 4.761 ,373; US 5.331 ,107; US 5.928,937; und US 5.378.824; sowie in der internationalen Veröffentlichung WO 96/033270 beschrieben. Weitere imidazolinontolerante Pflanzen sind auch in z. B. WO 2004/040012, WO 2004/106529, WO 2005/020673, WO 2005/093093, WO 2006/007373, WO 5,731,180; US 5,304,732; US 4,761,373; US 5,331,107; US 5,928,937; and US 5,378,824; and in international publication WO 96/033270. Other imidazolinontolerante plants are also in z. WO 2004/040012, WO 2004/106529, WO 2005/020673, WO 2005/093093, WO 2006/007373, WO
2006/015376, WO 2006/024351 und WO 2006/060634 beschrieben. Weitere 2006/015376, WO 2006/024351 and WO 2006/060634. Further
Sulfonylharnstoff- und imidazolinontolerante Pflanzen sind auch in z.B. WO Sulfonylurea and imidazolinone tolerant plants are also useful in e.g. WHERE
2007/024782 beschrieben. Weitere Pflanzen, die gegenüber ALS-Inhibitoren, insbesondere gegenüber 2007/024782 described. Other plants that are resistant to ALS inhibitors, especially against
Imidazolinonen, Sulfonylharnstoffen und/oder Sulfamoylcarbonyltriazolinonen tolerant sind, können durch induzierte Mutagenese, Selektion in Zellkulturen in Gegenwart des Herbizids oder durch Mutationszüchtung erhalten werden, wie dies zum Beispiel für die Sojabohne in US 5,084,082, für Reis in WO 97/41218, für die Zuckerrübe in US 5.773,702 und WO 99/057965, für Salat in US 5,198,599 oder für die Sonnenblume in WO 2001/065922 beschrieben ist.  Imidazolinones, sulfonylureas and / or sulfamoylcarbonyltriazolinones, can be obtained by induced mutagenesis, selection in cell cultures in the presence of the herbicide or by mutation breeding, as for example for the soybean in US 5,084,082, for rice in WO 97/41218, for the sugar beet in US 5,773,702 and WO 99/057965, for salad in US 5,198,599 or for the sunflower in WO 2001/065922.
Pflanzen oder Pflanzensorten (die nach Methoden der pflanzlichen Biotechnologie, wie der Gentechnik, erhalten wurden), die ebenfalls mit den erfindungsgemäßen Plants or plant varieties (obtained by plant biotechnology methods, such as genetic engineering), which are also with the inventive
Verbindungen der allgemeinen Formel (I) behandelt werden können, sind Compounds of general formula (I) can be treated are
insektenresistente transgene Pflanzen, d.h. Pflanzen, die gegen Befall mit gewissen Zielinsekten resistent gemacht wurden. Solche Pflanzen können durch genetische Transformation oder durch Selektion von Pflanzen, die eine Mutation enthalten, die solch eine Insektenresistenz verleiht, erhalten werden. Der Begriff "insektenresistente transgene Pflanze" umfaßt im vorliegenden insect-resistant transgenic plants, ie plants that have been made resistant to attack by certain target insects. Such plants can be obtained by genetic transformation or by selection of plants containing a mutation conferring such insect resistance. The term "insect-resistant transgenic plant" as used herein
Zusammenhang jegliche Pflanze, die mindestens ein Transgen enthält, das eine Kodiersequenz umfaßt, die für folgendes kodiert: Relates to any plant containing at least one transgene comprising a coding sequence coding for:
1 ) ein Insektizides Kristallprotein aus Bacillus thuringiensis oder einen Insektiziden Teil davon, wie die Insektiziden Kristallproteine, die von Crickmore et al., Microbiology and Molecular Biology Reviews (1998), 62, 807-813, zusammengestellt wurden, von Crickmore et al. (2005) in der Bacillus thuringiensis-Toxinnomenklatur aktualisiert (online bei: 1) an insecticidal crystal protein from Bacillus thuringiensis or an insecticidal portion thereof, such as the insecticidal crystal proteins collected by Crickmore et al., Microbiology and Molecular Biology Reviews (1998), 62, 807-813, by Crickmore et al. (2005) in the Bacillus thuringiensis toxin nomenclature (online at:
http://www.lifesci.sussex.ac.uk/Home/Neil_Crickmore/Bt/), oder Insektizide Teile davon, z.B. Proteine der Cry-Proteinklassen Cry1 Ab, Cry1 Ac, Cry1 F, Cry2Ab, Cry3Ae oder Cry3Bb oder insektizide Teile davon; oder 2) ein Kristallprotein aus Bacillus thuringiensis oder einen Teil davon, der inhttp://www.lifesci.sussex.ac.uk/Home/Neil_Crickmore/Bt/), or insecticidal parts thereof, e.g. Proteins of Cry protein classes Cry1 Ab, Cry1 Ac, Cry1 F, Cry2Ab, Cry3Ae or Cry3Bb or insecticidal parts thereof; or 2) a crystal protein from Bacillus thuringiensis or a part thereof which is present in
Gegenwart eines zweiten, anderen Kristallproteins als Bacillus thuringiensis oder eines Teils davon insektizid wirkt, wie das binäre Toxin, das aus den Kristallproteinen Cy34 und Cy35 besteht ( oellenbeck et al., Nat. Biotechnol. (2001 ), 19, 668-72; Schnepf et al., Applied Environm. Microb. (2006), 71 , 1765-1774); oder Presence of a second, different crystal protein than Bacillus thuringiensis or a part thereof is insecticidal, such as the binary toxin consisting of the crystal proteins Cy34 and Cy35 (Oellenbeck et al., Nat. Biotechnol. (2001), 19, 668-72; Schnepf et al., Applied Environment Microb. (2006) 71, 1765-1774); or
3) ein Insektizides Hybridprotein, das Teile von zwei unterschiedlichen Insektiziden Kristallproteinen aus Bacillus thuringiensis umfaßt, wie zum Beispiel ein Hybrid aus den Proteinen von 1 ) oben oder ein Hybrid aus den Proteinen von 2) oben, z. B. das Protein Cry1 A.105, das von dem Mais-Event MON98034 produziert wird (WO 3) an insecticidal hybrid protein comprising parts of two different insecticides of Bacillus thuringiensis crystal proteins, such as a hybrid of the proteins of 1) above or a hybrid of the proteins of 2) above, e.g. For example, the protein Cry1 A.105 produced by the corn event MON98034 (WO
2007/027777); oder 2007/027777); or
4) ein Protein gemäß einem der Punkte 1 ) bis 3) oben, in dem einige, 4) a protein according to any one of items 1) to 3) above, in which some,
insbesondere 1 bis 10, Aminosäuren durch eine andere Aminosäure ersetzt wurden, um eine höhere insektizide Wirksamkeit gegenüber einer Zielinsektenart zu erzielen und/oder um das Spektrum der entsprechenden Zielinsektenarten zu erweitern und/oder wegen Veränderungen, die in die Kodier- DNA während der Kionierung oder Transformation induziert wurden, wie das Protein Cry3Bb1 in Mais-Events MON863 oder MON88017 oder das Protein Cry3A im Mais-Event MIR 604; oder 5) ein Insektizides sezerniertes Protein aus Bacillus thuringiensis oder Bacillus cereus oder einen Insektiziden Teil davon, wie die vegetativ wirkenden In particular 1 to 10, amino acids have been replaced by another amino acid to achieve higher insecticidal activity against a target insect species and / or to broaden the spectrum of the corresponding target insect species and / or due to changes in the coding DNA during the cationization or Transformation were induced, such as the protein Cry3Bb1 in maize events MON863 or MON88017 or the protein Cry3A in the maize event MIR 604; or 5) an insecticidal secreted protein from Bacillus thuringiensis or Bacillus cereus or an insecticidal part thereof, such as the vegetative
insektentoxischen Proteine (vegetative insecticidal proteins, VIP), die unter folgendem Link angeführt sind, z. B. Proteine der Proteinklasse VIP3Aa: insecticidal proteins (VIP) listed under the following link, e.g. B. Proteins of protein class VIP3Aa:
http://www.lifesci.sussex.ac.uk/Home/Neil_Crickmore/Bt/vip.html oder http://www.lifesci.sussex.ac.uk/Home/Neil_Crickmore/Bt/vip.html or
6) ein sezerniertes Protein aus Bacillus thuringiensis oder Bacillus cereus, das in Gegenwart eines zweiten sezernierten Proteins aus Bacillus thuringiensis oder B. cereus insektizid wirkt, wie das binäre Toxin, das aus den Proteinen VIP1A und VIP2A besteht (WO 94/21795); oder 6) a secreted protein from Bacillus thuringiensis or Bacillus cereus which is insecticidal in the presence of a second secreted protein from Bacillus thuringiensis or B. cereus, such as the binary toxin consisting of the proteins VIP1A and VIP2A (WO 94/21795); or
7) ein Insektizides Hybridprotein, das Teile von verschiedenen sezernierten Proteinen von Bacillus thuringiensis oder Bacillus cereus umfaßt, wie ein Hybrid der Proteine von 1 ) oder ein Hybrid der Proteine von 2) oben; oder 7) an insecticidal hybrid protein comprising parts of various secreted proteins of Bacillus thuringiensis or Bacillus cereus, such as a hybrid of the proteins of 1) or a hybrid of the proteins of 2) above; or
8) ein Protein gemäß einem der Punkte 1 ) bis 3) oben, in dem einige, 8) a protein according to any one of items 1) to 3) above, in which some,
insbesondere 1 bis 10, Aminosäuren durch eine andere Aminosäure ersetzt wurden, um eine höhere Insektizide Wirksamkeit gegenüber einer Zielinsektenart zu erzielen und/oder um das Spektrum der entsprechenden Zielinsektenarten zu erweitern und/oder wegen Veränderungen, die in die Kodier- DNA während der Klonierung oder Transformation induziert wurden (wobei die Kodierung für ein Insektizides Protein erhalten bleibt), wie das Protein VIP3Aa im Baumwoll-Event COT 102. In particular, 1 to 10, amino acids have been replaced by another amino acid to achieve higher insecticidal activity against a target insect species and / or to broaden the spectrum of the corresponding target insect species and / or due to changes in the coding DNA during cloning or Transformation (retaining coding for an insecticidal protein) such as protein VIP3Aa in cotton event COT 102.
Natürlich zählt zu den insektenresistenten transgenen Pflanzen im vorliegenden Zusammenhang auch jegliche Pflanze, die eine Kombination von Genen umfaßt, die für die Proteine von einer der oben genannten Klassen 1 bis 8 kodieren. In einer Ausführungsform enthält eine insektenresistente Pflanze mehr als ein Transgen, das für ein Protein nach einer der oben genannten 1 bis 8 kodiert, um das Spektrum der entsprechenden Zielinsektenarten zu erweitern oder um die Entwicklung einer Resistenz der Insekten gegen die Pflanzen dadurch hinauszuzögern, dass man verschiedene Proteine einsetzt, die für dieselbe Zielinsektenart insektizid sind, jedoch eine unterschiedliche Wirkungsweise, wie Bindung an unterschiedliche Of course, insect-resistant transgenic plants in the present context also include any plant comprising a combination of genes encoding the proteins of any of the above classes 1 to 8. In one embodiment, an insect resistant plant contains more than one transgene encoding a protein of any one of the above 1 to 8 in order to extend the spectrum of the corresponding target insect species or to delay the development of resistance of the insects to the plants by use different proteins which are insecticidal for the same target insect species, but a different mode of action, such as binding to different ones
Rezeptorbindungsstellen im Insekt, aufweisen. Pflanzen oder Pflanzensorten (die nach Methoden der pflanzlichen Biotechnologie, wie der Gentechnik, erhalten wurden), die ebenfalls mit den erfindungsgemäßen Receptor binding sites in the insect. Plants or plant varieties (obtained by plant biotechnology methods, such as genetic engineering), which are also with the inventive
Verbindungen der allgemeinen Formel (I) behandelt werden können, sind gegenüber abioti sehen Streßfaktoren tolerant. Solche Pflanzen können durch genetische Compounds of general formula (I) are tolerant to abiotic stress factors. Such plants can be caused by genetic
Transformation oder durch Selektion von Pflanzen, die eine Mutation enthalten, die solch eine Streßresistenz verleiht, erhalten werden. Zu besonders nützlichen Pflanzen mit Streßtoleranz zählen folgende: a. Pflanzen, die ein Transgen enthalten, das die Expression und/oder Aktivität des Gens für die Poly(ADP-ribose)polymerase (PA P) in den Pflanzenzellen oder Transformation or by selection of plants containing a mutation conferring such stress resistance. Particularly useful plants with stress tolerance include the following: a. Plants which contain a transgene which has the expression and / or activity of the gene for the poly (ADP-ribose) polymerase (PA P) in the plant cells or
Pflanzen zu reduzieren vermag, wie dies in WO 2000/004173 oder EP 04077984.5 oder EP 06009836.5 beschrieben ist. b. Pflanzen, die ein streßtoleranzförderndes Transgen enthalten, das die  To reduce plants, as described in WO 2000/004173 or EP 04077984.5 or EP 06009836.5. b. Plants containing a stress tolerance-enhancing transgene which causes the
Expression und/oder Aktivität der für PARG kodierenden Gene der Pflanzen oder Pflanzenzellen zu reduzieren vermag, wie dies z.B. in WO 2004/090140 beschrieben ist; c. Pflanzen, die ein streßtoleranzförderndes Transgen enthalten, das für ein in Pflanzen funktionelles Enzym des Nicotinamidadenindinukleotid-Salvage-To reduce expression and / or activity of PARG-encoding genes of plants or plant cells, as described e.g. in WO 2004/090140 is described; c. Plants containing a stress tolerance enhancing transgene useful for a plant functional enzyme of nicotinamide adenine dinucleotide salvage
Biosynthesewegs kodiert, darunter Nicotinamidase, Biosynthetic pathway, including nicotinamidase,
Nicotinatphosphoribosyltransferase, Nicotinsäuremononukleotid-adenyltransferase, Nicotinamidadenindinukleotidsynthetase oder Nicotinamidphosphoribosyl-transferase, wie dies z. B. in EP 04077624.7 oder WO 2006/133827 oder PCT/EP07/002433 beschrieben ist.  Nicotinate phosphoribosyltransferase, nicotinic acid mononucleotide adenyltransferase, nicotinamide adenine dinucleotide synthetase or nicotinamide phosphoribosyltransferase, as described e.g. As described in EP 04077624.7 or WO 2006/133827 or PCT / EP07 / 002433.
Pflanzen oder Pflanzensorten (die nach Methoden der pflanzlichen Biotechnologie, wie der Gentechnik, erhalten wurden), die ebenfalls mit den erfindungsgemäßen Plants or plant varieties (obtained by plant biotechnology methods, such as genetic engineering), which are also with the inventive
Verbindungen der allgemeinen Formel (I) behandelt werden können, weisen eine veränderte Menge, Qualität und/oder Lagerfähigkeit des Ernteprodukts und/oder veränderte Eigenschaften von bestimmten Bestandteilen des Ernteprodukts auf, wie zum Beispiel: 1 ) Transgene Pflanzen, die eine modifizierte Stärke synthetisieren, die bezüglich ihrer chemisch-physikalischen Eigenschaften, insbesondere des Amylosegehalts oder des Amylose/Amylopektin-Verhältnisses, des Verzweigungsgrads, der Compounds of general formula (I) may have an altered amount, quality and / or shelf life of the crop and / or altered properties of certain components of the crop, such as: 1) Transgenic plants that synthesize a modified starch, with respect to their chemical-physical properties, in particular the amylose content or the amylose / amylopectin ratio, the degree of branching, the
durchschnittlichen Kettenlänge, der Verteilung der Seitenketten, des average chain length, the distribution of side chains, the
Viskositätsverhaltens, der Gelfestigkeit, der Stärkekorngröße und/oder Viscosity behavior, the gel strength, the starch grain size and / or
Stärkekornmorphologie im Vergleich mit der synthetisierten Stärke in Starch grain morphology in comparison with the synthesized starch in
Wildtyppflanzenzellen oder -pflanzen verändert ist, so dass sich diese modifizierte Stärke besser für bestimmte Anwendungen eignet. Diese transgenen Pflanzen, die eine modifizierte Stärke synthetisieren, sind zum Beispiel in EP 0571427, WO Wild-type plant cells or plants, so that this modified starch is better suited for certain applications. These transgenic plants synthesizing a modified starch are described, for example, in EP 0571427, WO
95/004826, EP 0719338, WO 96/15248, WO 96/19581 , WO 96/27674, WO 97/1 1 188, WO 97/26362, WO 97/32985, WO 97/42328, WO 97/44472, WO 97/45545, WO 98/27212, WO 98/40503, WO 99/58688. WO 99/58690, WO 99/58654, WO 95/004826, EP 0719338, WO 96/15248, WO 96/19581, WO 96/27674, WO 97/1 1 188, WO 97/26362, WO 97/32985, WO 97/42328, WO 97/44472, WO 97/45545, WO 98/27212, WO 98/40503, WO 99/58688. WO 99/58690, WO 99/58654, WO
2000/008184. WO 2000/008185, WO 2000/28052, WO 2000/77229, WO 2001/12782, WO 2001 /12826, WO 2002/101059, WO 2003/071860, WO 2004/056999, WO 2000/008184. WO 2000/008185, WO 2000/28052, WO 2000/77229, WO 2001/12782, WO 2001/12826, WO 2002/101059, WO 2003/071860, WO 2004/056999, WO
2005/030942, WO 2005/030941 , WO 2005/095632, WO 2005/095617, WO 2005/030942, WO 2005/030941, WO 2005/095632, WO 2005/095617, WO
2005/095619, WO 2005/095618, WO 2005/123927, WO 2006/018319, WO 2005/095619, WO 2005/095618, WO 2005/123927, WO 2006/018319, WO
2006/103107, WO 2006/108702, WO 2007/009823, WO 2000/22140, WO 2006/103107, WO 2006/108702, WO 2007/009823, WO 2000/22140, WO
2006/063862, WO 2006/072603, WO 2002/034923, EP 06090134.5, EP 06090228.5, EP 06090227.7, EP 07090007.1 , EP 07090009.7, WO 2001 /14569, WO 2002/79410, WO 2003/33540, WO 2004/078983, WO 2001/19975, WO 95/26407, WO 96/34968, WO 98/20145, WO 99/12950, WO 99/66050, WO 99/53072, US 6,734.341 , WO 2000/1 1 192, WO 98/22604, WO 98/32326, WO 2001/98509, WO 2001 /98509, WO 2005/002359, US 5,824,790, US 6,013.861 , WO 94/004693, WO 94/009144, WO 94/1 1520, WO 95/35026 bzw. WO 97/20936 beschrieben. Publication No. 2006/063862, WO 2006/072603, WO 2002/034923, EP 06090134.5, EP 06090228.5, EP 06090227.7, EP 07090007.1, EP 07090009.7, WO 2001/14569, WO 2002/79410, WO 2003/33540, WO 2004/078983, WO No. 2001/19975, WO 95/26407, WO 96/34968, WO 98/20145, WO 99/12950, WO 99/66050, WO 99/53072, US Pat. No. 6,734,341, WO 2000/1 1 192, WO 98/22604, WO 98/32326, WO 2001/98509, WO 2001/98509, WO 2005/002359, US 5,824,790, US 6,013,861, WO 94/004693, WO 94/009144, WO 94/1 1520, WO 95/35026 and WO 97 / 20936 described.
2) Transgene Pflanzen, die Nichtstärkekohlenhydratpolymere synthetisieren, oder Nichtstärkekohlenhydratpolymere, deren Eigenschaften im Vergleich zu 2) Transgenic plants that synthesize non-starch carbohydrate polymers, or non-starch carbohydrate polymers whose properties are compared to
Wildtyppflanzen ohne genetische Modifikation verändert sind. Beispiele sind Pflanzen, die Polyfructose, insbesondere des Inuiin- und Levantyps, produzieren, wie dies in EP 0663956, WO 96/001904, Wo 96/021023, WO 98/039460 und WO 99/024593 beschrieben ist, Pflanzen, die alpha-1 ,4-Glucane produzieren, wie dies in WO Wildtype plants are modified without genetic modification. Examples are plants which produce polyfructose, in particular of the inuiin and levan type, as described in EP 0663956, WO 96/001904, Wo 96/021023, WO 98/039460 and WO 99/024593, plants which are alpha-1 To produce 4-glucans, as in WO
95/031553, US 2002/031826, US 6,284.479, US 5,712,107, WO 97/047806, WO 97/047807, WO 97/047808 und WO 2000/14249 beschrieben ist, Pflanzen, die alpha- 1 ,6-verzweigte alpha-1 ,4-Glucane produzieren, wie dies in WO 2000/73422 beschrieben ist, und Pflanzen, die Alternan produzieren, wie dies in WO 2000/047727, EP 06077301 .7, US 5.908,975 und EP 0728213 beschrieben ist. 95/031553, US 2002/031826, US 6,284,479, US 5,712,107, WO 97/047806, WO 97/047807, WO 97/047808 and WO 2000/14249, plants which are alpha-1, 6-branched alpha-1 4-glucans, as described in WO 2000/73422 and plants which produce alternan, as described in WO 2000/047727, EP 06077301.7, US 5,908,975 and EP 0728213.
3) Transgene Pflanzen, die Hyaluronan produzieren, wie dies zum Beispiel in WO 06/032538, WO 2007/039314, WO 2007/039315, WO 2007/039316, JP 2006/304779 und WO 2005/012529 beschrieben ist. 3) Transgenic plants which produce hyaluronan, as described, for example, in WO 06/032538, WO 2007/039314, WO 2007/039315, WO 2007/039316, JP 2006/304779 and WO 2005/012529.
Pflanzen oder Pflanzensorten (die nach Methoden der pflanzlichen Biotechnologie, wie der Gentechnik, erhalten wurden), die ebenfalls mit den erfindungsgemäßen Plants or plant varieties (obtained by plant biotechnology methods, such as genetic engineering), which are also with the inventive
Verbindungen der allgemeinen Formel (I) behandelt werden können, sind Pflanzen wie Baumwollpfianzen mit veränderten Fasereigenschaften. Solche Pflanzen können durch genetische Transformation oder durch Selektion von Pflanzen, die eine Mutation enthalten, die solche veränderten Fasereigenschaften verleiht, erhalten werden; dazu zählen: a) Pflanzen wie Baumwollpflanzen, die eine veränderte Form von Compounds of general formula (I) can be treated are plants such as cotton plants with altered fiber properties. Such plants can be obtained by genetic transformation or by selection of plants containing a mutation conferring such altered fiber properties; These include: a) plants, such as cotton plants, which have an altered form of
Cellulosesynthasegenen enthalten, wie dies in WO 98/000549 beschrieben ist, b) Pflanzen wie Baumwollpflanzen, die eine veränderte Form von rsw2- oder rsw3- homologen Nukleinsäuren enthalten, wie dies in WO 2004/053219 beschrieben ist; c) Pflanzen wie Baumwollpflanzen mit einer erhöhten Expression der Contain cellulose synthase genes, as described in WO 98/000549, b) plants such as cotton plants containing an altered form of rsw2 or rsw3 homologous nucleic acids, as described in WO 2004/053219; c) plants such as cotton plants with an increased expression of the
Saccharosephosphatsynthase, wie dies in WO 2001/017333 beschrieben ist; d) Pflanzen wie Baumwollpflanzen mit einer erhöhten Expression der Sucrose phosphate synthase as described in WO 2001/017333; d) plants such as cotton plants with an increased expression of
Saccharosesynthase, wie dies in WO 02/45485 beschrieben ist; e) Pflanzen wie Baumwollpflanzen bei denen der Zeitpunkt der Durchlaßsteuerung der Plasmodesmen an der Basis der Faserzelle verändert ist, z. B. durch Sucrose synthase as described in WO 02/45485; e) plants such as cotton plants in which the timing of the passage control of the Plasmodesmen is changed at the base of the fiber cell, z. B. by
Herunterregulieren der faserselektiven ß-1 ,3-Glucanase, wie dies in WO 2005/017157 beschrieben ist; f) Pflanzen wie Baumwollpflanzen mit Fasern mit veränderter Reaktivität, z. B. durch Expression des N-Acetylglucosamintransferasegens, darunter auch nodC, und von Chitinsynthasegenen, wie dies in WO 2006/136351 beschrieben ist. Pflanzen oder Pflanzensorten (die nach Methoden der pflanzlichen Biotechnologie, wie der Gentechnik, erhalten wurden), die ebenfalls mit den erfindungsgemäßen Down-regulating the fiber-selective β-1,3-glucanase as described in WO 2005/017157; f) plants such as cotton plants with modified reactivity fibers, e.g. By expression of the N-acetylglucosamine transferase gene, including nodC, and chitin synthase genes, as described in WO 2006/136351. Plants or plant varieties (obtained by plant biotechnology methods, such as genetic engineering), which are also with the inventive
Verbindungen der allgemeinen Formel (I) behandelt werden können, sind Pflanzen wie Raps oder verwandte Brassica-Pflanzen mit veränderten Eigenschaften der ölzusammensetzung. Solche Pflanzen können durch genetische Transformation oder durch Selektion von Pflanzen, die eine Mutation enthalten, die solche veränderten öleigenschaften verleiht, erhalten werden; dazu zählen: a) Pflanzen wie Rapspflanzen, die öl mit einem hohen ölsäuregehalt produzieren, wie dies zum Beispiel in US 5,969,169, US 5.840,946 oder US 6,323,392 oder US 6.063, 947 beschrieben ist; b) Pflanzen wie Rapspflanzen, die öl mit einem niedrigen Linolensäuregehalt produzieren, wie dies in US 6,270828, US 6.169,190 oder US 5.965,755 beschrieben ist. c) Pflanzen wie Rapspflanzen, die öl mit einem niedrigen gesättigten Compounds of general formula (I) can be treated are plants such as rapeseed or related Brassica plants with altered properties of the oil composition. Such plants can be obtained by genetic transformation or by selection of plants containing a mutation conferring such altered oil properties; These include: a) plants such as rape plants producing high oleic acid oil, as described, for example, in US 5,969,169, US 5,840,946 or US 6,323,392 or US 6,063,947; b) plants such as oilseed rape plants which produce low linolenic acid oil, as described in US 6,270,828, US 6,169,190 or US 5,965,755. c) plants such as oilseed rape plants, the oil with a low saturated
Fettsäuregehalt produzieren, wie dies z. B. in US 5,434.283 beschrieben ist. Produce fatty acid content, as z. As described in US 5,434,283.
Besonders nützliche transgene Pflanzen, die mit den erfindungsgemäßen Particularly useful transgenic plants with the inventive
Verbindungen der allgemeinen Formel (I) behandelt werden können, sind Pflanzen, die Transformations-Events, oder eine Kombination von Transformations-Events, enthalten und die zum Beispiel in den Dateien von verschiedenen nationalen oder regionalen Behörden angeführt sind. Besonders nützliche transgene Pflanzen, die mit den erfindungsgemäßen Compounds of general formula (I) may be treated as plants containing transformation events, or a combination of transformation events, for example as listed in the files of various national or regional authorities. Particularly useful transgenic plants with the inventive
Verbindungen der allgemeinen Formel (I) behandelt werden können, sind beispielhaft Pflanzen mit einem oder mehreren Genen, die für ein oder mehrere Toxine kodieren, sind die transgenen Pflanzen, die unter den folgenden Handelsbezeichnungen angeboten werden: YIELD GARD® (zum Beispiel Mais, Baumwolle, Sojabohnen), KnockOut® (zum Beispiel Mais), BiteGard® (zum Beispiel Mais), BT-Xtra® (zum Beispiel Mais), StarLink® (zum Beispiel Mais), Bollgard® (Baumwolle), Nucotn® (Baumwolle), Nucotn 33B® (Baumwolle), NatureGard® (zum Beispiel Mais), Exemplary plants having one or more genes encoding one or more toxins are the transgenic plants available under the following tradenames: YIELD GARD® (for example, corn, cotton , Soybeans), KnockOut® (for example corn), BiteGard® (for example maize), BT-Xtra® (for example maize), StarLink® (for example maize), Bollgard® (cotton), Nucotn® (cotton), Nucotn 33B® ( Cotton), NatureGard® (for example corn),
Protecta® und NewLeaf® (Kartoffel). Herbizidtolerante Pflanzen, die zu erwähnen sind, sind zum Beispiel Maissorten, Baumwollsorten und Sojabohnensorten, die unter den folgenden Handelsbezeichnungen angeboten werden: Roundup Ready® Protecta® and NewLeaf® (potato). Herbicide-tolerant crops to be mentioned include, for example, corn, cotton and soybean varieties sold under the following tradenames: Roundup Ready®
(Glyphosatetoleranz, zum Beispiel Mais, Baumwolle, Sojabohne), Liberty Link® (Phosphinotricintoleranz, zum Beispiel Raps), IMI® (Imidazolinontoleranz) und SCS® (Sylfonylharnstofftoleranz), zum Beispiel Mais. Zu den herbizidresistenten Pflanzen (traditionell auf Herbizidtoleranz gezüchtete Pflanzen), die zu erwähnen sind, zählen die unter der Bezeichnung Clearfield® angebotenen Sorten (zum Beispiel Mais). (Glyphosate tolerance, for example corn, cotton, soybean), Liberty Link® (phosphinotricin tolerance, for example rapeseed), IMI® (imidazolinone tolerance) and SCS® (sylphonylurea tolerance), for example maize. Herbicide-resistant plants (plants traditionally grown for herbicide tolerance) to be mentioned include the varieties sold under the name Clearfield® (for example corn).
Die erfindungsgemäß zu verwendenden Verbindungen der Formel (I) können in übliche Formulierungen überführt werden, wie Lösungen, Emulsionen, Spritzpulver, wasser- und ölbasierte Suspensionen, Pulver, Stäubemittel, Pasten, lösliche Pulver, lösliche Granulate, Streugranulate, Suspensions-Emulsions-Konzentrate, Wirkstoff- imprägnierte Naturstoffe, Wirkstoff-imprägnierte synthetische Stoffe, Düngemittel sowie Feinstverkapselungen in polymeren Stoffen. Im Rahmen der vorliegenden Erfindung ist es insbesondere bevorzugt, wenn die Verbindungen der allgemeinen Formel (I) in der Form einer Sprühformulieruing verwendet werden. The compounds of the formula (I) to be used according to the invention can be converted into customary formulations, such as solutions, emulsions, wettable powders, water- and oil-based suspensions, powders, dusts, pastes, soluble powders, soluble granules, scattering granules, suspension-emulsion concentrates, Active substance-impregnated natural substances, active substance-impregnated synthetic substances, fertilizers and microencapsulation in polymeric substances. In the context of the present invention it is particularly preferred if the compounds of the general formula (I) are used in the form of a spray formulation.
Die vorliegende Erfindung betrifft daher darüber hinaus auch eine Sprühformulierung zur Steigerung der Widerstandsfähigkeit von Pflanzen gegenüber abiotischem Stress. Im Folgenden wird eine Sprühformulierung näher beschrieben: The present invention therefore further relates to a spray formulation for increasing the resistance of plants to abiotic stress. In the following, a spray formulation is described in more detail:
Die Formulierungen zur Sprühapplikation werden in bekannter Weise hergestellt, z.B. durch Vermischen der erfindungsgemäß zu verwendenden Verbindungen der allgmeinen Formel (I) mit Streckmitteln, also flüssigen Lösungsmitteln und/oder festen Trägerstoffen, gegebenenfalls unter Verwendung von oberflächenaktiven Mitteln, also Emulgiermitteln und/oder Dispergiermitteln und/oder schaumerzeugenden Mitteln. Weitere übliche Zusatzstoffe, wie zum Beispiel übliche Streckmittel sowie Lösungsoder Verdünnungsmittel, Farbstoffe, Netzmittel, Dispergiermittel, Emulgatoren, Entschäumer, Konservierungsmittel, sekundäre Verdickungsmittel, Kleber, Gibberelline und auch Wasser, können gegebenenfalls auch verwendet werden. Die Herstellung der Formulierungen erfolgt entweder in geeigneten Anlagen oder auch vor oder während der Anwendung. Als Hilfsstoffe können solche Stoffe Verwendung finden, die geeignet sind, dem Mittel selbst oder und/oder davon abgeleitete Zubereitungen (z.B. Spritzbrühen) besondere Eigenschaften zu verleihen, wie bestimmte technische Eigenschaften und/oder auch besondere biologische Eigenschaften. Als typische Hilfsmittel kommen in Frage: The formulations for spray application are prepared in a known manner, for example by mixing the compounds of the general formula (I) to be used according to the invention with extenders, ie liquid solvents and / or solid carriers, if appropriate using surface-active agents, ie emulsifiers and / or dispersants and or foam-producing agents. Other conventional additives, such as conventional extenders and solvents or diluents, dyes, wetting agents, dispersants, emulsifiers, defoamers, preservatives, secondary thickeners, adhesives, Gibberellins and also water may also be used if necessary. The preparation of the formulations is carried out either in suitable systems or before or during use. As excipients, it is possible to use those substances which are suitable for imparting special properties to the agent itself and / or preparations derived therefrom (for example spray liquors), such as certain technical properties and / or also particular biological properties. As typical aids are:
Streckmittel, Lösemittel und Trägerstoffe. Extenders, solvents and carriers.
Als Streckmittel eignen sich z.B. Wasser, polare und unpolare organische chemische Flüssigkeiten z.B. aus den Klassen der aromatischen und nicht-aromatischen As extender, e.g. Water, polar and non-polar organic chemical liquids e.g. from the classes of aromatic and non-aromatic
Kohlenwasserstoffe (wie Paraffine, Alkylbenzole, Alkylnaphthaline, Chlorbenzole), der Alkohole und Polyole (die ggf. auch substituiert, verethert und/oder verestert sein können), der Ketone (wie Aceton, Cyclohexanon), Ester (auch Fette und öle) und (Poly-)Ether, der einfachen und substituierten Amine, Amide, Lactame (wie N- Alkylpyrrolidone) und Lactone, der Sulfone und Sulfoxide (wie Dimethylsysulfoxid). Hydrocarbons (such as paraffins, alkylbenzenes, alkylnaphthalenes, chlorobenzenes), alcohols and polyols (which may also be substituted, etherified and / or esterified), ketones (such as acetone, cyclohexanone), esters (including fats and oils) and ( Poly) ethers, simple and substituted amines, amides, lactams (such as N-alkylpyrrolidones) and lactones, sulfones and sulfoxides (such as dimethyl sulfoxide).
Im Falle der Benutzung von Wasser als Streckmittel können z.B. auch organische Lösemittel als Hilfslösungsmittel verwendet werden. Als flüssige Lösemittel kommen im wesentlichen in Frage: Aromaten, wie Xylol, Toluol, oder Alkylnaphthaline, chlorierte Aromaten und chlorierte aliphatische Kohlenwasserstoffe, wie Chlorbenzole, Chlorethylene oder Methylenchlorid, aliphatische Kohlenwasserstoffe, wie Cyclohexan oder Paraffine, z.B. Erdölfraktionen, mineralische und pflanzliche öle, Alkohole, wie Butanol oder Glykol sowie deren Ether und Ester, Ketone wie Aceton, Methylethyl- keton, Methylisobutylketon oder Cyclohexanon, stark polare Lösungsmittel, wie Dimethylsulfoxid, sowie Wasser. In the case of using water as an extender, e.g. also organic solvents can be used as auxiliary solvent. Suitable liquid solvents are essentially: aromatics, such as xylene, toluene, or alkylnaphthalenes, chlorinated aromatics and chlorinated aliphatic hydrocarbons, such as chlorobenzenes, chloroethylenes or methylene chloride, aliphatic hydrocarbons, such as cyclohexane or paraffins, e.g. Petroleum fractions, mineral and vegetable oils, alcohols such as butanol or glycol and their ethers and esters, ketones such as acetone, methyl ethyl ketone, methyl isobutyl ketone or cyclohexanone, strongly polar solvents such as dimethyl sulfoxide, and water.
Es können Farbstoffe wie anorganische Pigmente, z.B. Eisenoxid, Titanoxid, Ferro- cyanblau und organische Farbstoffe, wie Alizarin-, Azo- und Metallphthalocyanin- farb Stoffe und Spurennährstoffe wie Salze von Eisen, Mangan, Bor, Kupfer, Kobalt, Molybdän und Zink verwendet werden. Als Netzmittel, die in den erfindungsgemäß verwendbaren Formulierungen enthalten sein können, kommen alle zur Formulierung von agrochemischen Wirkstoffen üblichen, die Benetzung fördernden Stoffe in Frage. Vorzugsweise verwendbar sind Alkylnaphthalin-Sulfonate, wie Diisopropyl- oder Diisobutylnaphthalin-Sulfonate. It is possible to use dyes such as inorganic pigments, for example iron oxide, titanium oxide, ferrocyan blue and organic dyes, such as alizarin, azo and metal phthalocyanine dyes and trace nutrients such as salts of iron, manganese, boron, copper, cobalt, molybdenum and zinc , Suitable wetting agents which may be present in the formulations which can be used according to the invention are all wetting-promoting substances customary for the formulation of agrochemical active compounds. Preferably usable are alkylnaphthalene sulfonates such as diisopropyl or diisobutylnaphthalene sulfonates.
Als Dispergiermittel und/oder Emulgatoren, die in den erfindungsgemäß verwendbaren Formulierungen enthalten sein können, kommen alle zur Formulierung von agrochemischen Wirkstoffen üblichen nichtionischen, anionischen und kationischen Dispergiermittel in Betracht. Vorzugsweise verwendbar sind nichtionische oder anionische Dispergiermittel oder Gemische von nichtionischen oder anionischen Dispergiermitteln. Als geeignete nichtionische Dispergiermittel sind insbesondere Ethylenoxid- Propylenoxid-Blockpolymere, Alkylphenolpolyglykolether sowie Tristryrylphenol- polyglykolether und deren phosphatierte oder sulfatierte Derivate zu nennen. Geeignete anionische Dispergiermittel sind insbesondere Ligninsulfonate, Poly- acrylsäuresalze und Arylsulfonat-Formaldehydkondensate. Suitable dispersants and / or emulsifiers which may be present in the formulations which can be used according to the invention are all nonionic, anionic and cationic dispersants customary for the formulation of agrochemical active compounds. Preferably usable are nonionic or anionic dispersants or mixtures of nonionic or anionic dispersants. Particularly suitable nonionic dispersants are ethylene oxide-propylene oxide block polymers, alkylphenol polyglycol ethers and tristryrylphenol polyglycol ethers and their phosphated or sulfated derivatives. Suitable anionic dispersants are in particular lignosulfonates, polyacrylic acid salts and arylsulfonate-formaldehyde condensates.
Als Entschäumer können in den erfindungsgemäß verwendbaren Formulierungen alle zur Formulierung von agrochemischen Wirkstoffen üblichen schaumhemmenden Stoffe enthalten sein. Vorzugsweise verwendbar sind Silikonentschäumer und Magne- siumstearat. Defoamers which may be present in the formulations which can be used according to the invention are all foam-inhibiting substances customary for the formulation of agrochemical active compounds. Preference is given to using silicone defoamers and magnesium stearate.
Als Konservierungsmittel können in den erfindungsgemäß verwendbaren As preservatives can be used in the invention
Formulierungen alle für derartige Zwecke in agrochemischen Mitteln einsetzbaren Stoffe vorhanden sein. Beispielhaft genannt seien Dichlorophen und Benzylalkohol- hemiformal. Formulations all substances that can be used for such purposes in agrochemical agents be present. Examples include dichlorophen and benzyl alcohol hemiformal.
Als sekundäre Verdickungsmittel, die in den erfindungsgemäß verwendbaren Formulierungen enthalten sein können, kommen alle für derartige Zwecke in agrochemischen Mitteln einsetzbaren Stoffe in Frage. Vorzugsweise in Betracht kommen Cellulose- derivate, Acrylsäurederivate, Xanthan, modifizierte Tone und hochdisperse Kieselsäure. Suitable secondary thickeners which may be present in the formulations which can be used according to the invention are all substances which can be used for such purposes in agrochemical compositions. Preferably suitable are cellulose derivatives, acrylic acid derivatives, xanthan, modified clays and finely divided silica.
Als Kleber, die in den erfindungsgemäß verwendbaren Formulierungen enthalten sein können, kommen alle üblichen in Beizmitteln einsetzbaren Bindemittel in Frage. Vorzugsweise genannt seien Polyvinylpyrrolidon, Polyvinylacetat, Polyvinylalkohol und Tylose. Als Gibberelline, die in den erfindungsgemäß verwendbaren Formulierungen enthalten sein können, kommen vorzugsweise die Gibberelline A1 , A3 (= Suitable adhesives which may be present in the formulations which can be used according to the invention are all customary binders which can be used in pickling agents. Preferably mentioned are polyvinylpyrrolidone, polyvinyl acetate, polyvinyl alcohol and Tylose. As gibberellins which may be present in the formulations which can be used according to the invention, the gibberellins A1, A3 (=
Gibberellinsäure), A4 und A7 infrage, besonders bevorzugt verwendet man die Gibberellinic acid), A4 and A7 in question, particularly preferably using the
Gibberellinsäure. Die Gibberelline sind bekannt (vgl. R. Wegler„Chemie der Gibberellic acid. The gibberellins are known (see R. Wegler "Chemie der
Pflanzenschutz- und Schädlingsbekämpfungsmittel", Bd. 2, Springer Verlag, 1970, S. 401 -412).  Phytosanitary and Pesticides ", Vol. 2, Springer Verlag, 1970, pp. 401-412).
Weitere Additive können Duftstoffe, mineralische oder vegetabilische gegebenenfalls modifizierte öle, Wachse und Nährstoffe (auch Spurennährstoffe), wie Salze vonOther additives may be fragrances, mineral or vegetable optionally modified oils, waxes and nutrients (also micronutrients), such as salts of
Eisen, Mangan, Bor, Kupfer, Kobalt, Molybdän und Zink sein. Weiterhin enthalten sein können Stabilisatoren wie Kältestabilisatoren, Oxidationsschutzmittel, Lichtschutzmittel oder andere die chemische und / oder physikalische Stabilität verbessernde Mittel. Die Formulierungen enthalten im allgemeinen zwischen 0.01 und 98 Gew.-%, vorzugsweise zwischen 0,5 und 90 %, der Verbindung der allgemeinen Formel (I). Iron, manganese, boron, copper, cobalt, molybdenum and zinc. Stabilizers such as cold stabilizers, antioxidants, light stabilizers or other chemical and / or physical stability improving agents may also be included. The formulations generally contain between 0.01 and 98% by weight, preferably between 0.5 and 90%, of the compound of general formula (I).
Die erfindungsgemäßen Verbindungen der allgemeinen Formel (I) können in handelsüblichen Formulierungen sowie in den aus diesen Formulierungen bereiteten Anwendungsformen in Mischung mit anderen Wirkstoffen wie Insektiziden, The compounds of the general formula (I) according to the invention can be prepared in commercial formulations and in the formulations prepared from these formulations in admixture with other active substances such as insecticides,
Lockstoffen, Sterilantien, Bakteriziden, Akariziden, Nematiziden, Fungiziden, wachstumsregulierenden Stoffen, Herbiziden, Safenern, Düngemitteln oder Attractants, sterilants, bactericides, acaricides, nematicides, fungicides, growth regulators, herbicides, safeners, fertilizers or
Semiochemicals vorliegen. Ferner lässt sich die beschriebene positive Wirkung der Verbindungen der Formel (I) auf die pflanzeneigenen Abwehrkräfte durch eine zusätzliche Behandlung mit insektziden, fungiziden oder bakteriziden Wirkstoffen unterstützen. Semiochemicals are present. Furthermore, the described positive effect of the compounds of the formula (I) on the plant's own defenses can be assisted by additional treatment with insecticidal, fungicidal or bactericidal active substances.
Bevorzugte Zeitpunkte für die Applikation der erfindungsgemäß zu verwendenden Verbindungen der allgemeinen Formel (I) oder deren Salze zur Steigerung der Preferred times for the application of the compounds of the general formula (I) to be used according to the invention or their salts for increasing the
Resistenz gegenüber abiotischem Stress sind Boden-, Stamm- und/oder Resistance to abiotic stress is soil, strain and / or
Blattbehandlungen mit den zugelassenen Aufwandmengen. Die erfindungsgemäß zu verwendenden Wirkstoffe der allgemeinen Formel (I) oder deren Salze können im Allgemeinen darüber hinaus in ihren handelsüblichen Leaf treatments with the approved application rates. The active compounds of the general formula (I) or salts thereof to be used according to the invention can generally also be used in their commercial form
Formulierungen sowie in den aus diesen Formulierungen bereiteten Formulations and in those prepared from these formulations
Anwendungsformen in Mischungen mit anderen Wirkstoffen, wie Insektiziden, Forms of use in mixtures with other active substances, such as insecticides,
Lockstoffen, Sterilantien, Akariziden, Nematiziden, Fungiziden, Bakteriziden, wachstumsregulierenden Stoffen, die Pflanzenreife beeinflussenden Stoffen, Safenern oder Herbiziden vorliegen. Besonders günstige Mischpartner sind beispielsweise die nachfolgend gruppenweise genannten Wirkstoffe der verschiedenen Klassen, ohne dass durch deren Reihenfolge eine Präferenz gesetzt wird: Attractants, sterilants, acaricides, nematicides, fungicides, bactericides, growth regulators, the plant maturity affecting substances, safeners or herbicides. Particularly favorable mixing partners are, for example, the active substances of the various classes which are mentioned below in groups, without preference being given to their order:
Fungizide: fungicides:
F1 ) Inhibitoren der Nucleinsäure Synthese, z. B. Benalaxyl, Benalaxyl-M, Bupirimat, Chiralaxyl, Clozylacon, Dimethirimol, Ethirimol, Furalaxyl, Hymexazol, Metalaxyl, Metalaxyl-M, Ofurace, Oxadixyl, Oxolinsäure; F1) inhibitors of nucleic acid synthesis, e.g. Benalaxyl, benalaxyl-M, bupirimate, chiralaxyl, clozylacon, dimethirimol, ethirimol, furalaxyl, hymexazole, metalaxyl, metalaxyl-M, ofurace, oxadixyl, oxolinic acid;
F2) Inhibitoren der Mitose und Zellteilung, z. B. Benomyl, Carbendazim, Diethofencarb, Fuberidazole, Fluopicolid, Pencycuron, Thiabendazol, Thiophanat-methyl, Zoxamid und Chlor-7-(4-methylpiperidin-1-yl)-6-(2,4,6- Trifluorphenyl [1 ,2,4]triazolo[1 ,5- a]pyrimidin; F2) inhibitors of mitosis and cell division, e.g. Benomyl, carbendazim, diethofencarb, fuberidazole, fluopicolide, pencycuron, thiabendazole, thiophanate-methyl, zoxamide and chloro-7- (4-methylpiperidin-1-yl) -6- (2,4,6-trifluorophenyl) [1, 2 , 4] triazolo [1,5-a] pyrimidine;
F3) Inhibitoren der Atmungskette Komplex I / II, z. B. Difiumetorim, Bixafen, Boscalid, Carboxin, Diflumethorim Fenfuram, Fluopyram, Flutolanil, Furametpyr, Mepronil, Oxycarboxin, Penflufen, Penthiopyrad, Thifluzamid, N-[2-(1 ,3-Dimethylbutyl)phenyl]-5- fluor-1 ,3-dimethyl-1 H-pyrazol-4-carboxamid, Isopyrazam, Sedaxan, 3-(Difluormethyl)- 1 -methyl-N-(3',4'.5'-trifluorbiphenyl-2-yl)-1 H-pyrazol-4-carboxamid, 3-(Difluormethyl)-1- methyl-N-[2-(1 ,1 ,2,2-tetrafluorethoxy)phenyl]-1 H-pyrazol-4-carboxamid, 3- (Difluormethyl)-N-[4-fluoro-2-(1 ,1 ,2,3,3,3-hexafluorpropoxy)phenyl]-1 -methyl-1 H- pyrazol-4-carboxamid, N-[1 -(2,4-Dichlorphenyl)-1 -methoxypropan-2-yl]-3- (difluormethyl)-l -methyl-1 H-pyrazol-4-carboxamid und entsprechende Salze; F3) inhibitors of the respiratory chain complex I / II, z. Difiumetorim, bixafen, boscalid, carboxin, diflumethorim fenfuram, fluopyram, flutolanil, furametpyr, mepronil, oxycarboxine, penflufen, penthiopyrad, thifluzamide, N- [2- (1,3-dimethylbutyl) phenyl] -5-fluoro-1, 3-dimethyl-1H-pyrazole-4-carboxamide, isopyrazam, sedaxane, 3- (difluoromethyl) -1-methyl-N- (3 ', 4'5'-trifluorobiphenyl-2-yl) -1H-pyrazole 4-carboxamide, 3- (difluoromethyl) -1-methyl-N- [2- (1, 1, 2,2-tetrafluoroethoxy) phenyl] -1H-pyrazole-4-carboxamide, 3- (difluoromethyl) -N - [4-fluoro-2- (1,1,3,3,3,3-hexafluoropropoxy) phenyl] -1-methyl-1H-pyrazole-4-carboxamide, N- [1- (2,4-dichlorophenyl ) -1-methoxypropan-2-yl] -3- (difluoromethyl) -1-methyl-1H-pyrazole-4-carboxamide and corresponding salts;
F4) Inhibitoren der Atmungskette Komplex III, z. B.Amisulbrom, Azoxystrobin, F4) inhibitors of the respiratory chain complex III, z. B. amisulbrom, azoxystrobin,
Cyazofamid, Dimoxystrobin, Enestrobin, Famoxadon, Fenamidon, Fluoxastrobin, Kresoximmethyl, Metominostrobin, Orysastrobin, Pyraclostrobin, Pyribencarb, Cyazofamide, dimoxystrobin, enestrobin, famoxadone, fenamidone, fluoxastrobin, Kresoximethyl, metominostrobin, orysastrobin, pyraclostrobin, pyribencarb,
Picoxystrobin, Trifioxystrobin, (2E)-2-(2-{[6-(3-Chlor-2-methylphenoxy)-5- fluorpyrimidin-4-yl]oxy}phenyl)-2-(methoxyimino)-N-methylethanamid, (2E)-2- (Ethoxyimino)-N-methyl-2-(2-{[({(1 E)-1 -[3-(trifluoromethyl)- phenyl]ethyliden}amino)oxy]methy!}phenyl)ethanamid und entsprechende Salze, (2E)- 2-(Methoxyimino)-N-methyl-2-{2-[(E)-({1 -[3-(trifluormethyl)phenyl]ethoxy}- imino)methyl]phenyl}ethanamid, (2E)-2-{2-[({[(1 E)-1 -(3-{[(E)-1 -Fluor-2-phenylethenyl]- oxy}phenyl)ethyliden]amino}oxy)methyl]phenyl}-2-(methoxyimino)-N-methylethanamid, (2E)-2-{2-[({[(2E,3E)-4-(2.6-Dichlorophenyl)but-3-en-2- yliden]amino}oxy)methyl]phenyl}-2-(methoxyimino)-N-methylethanarnid, 2-Chlor-N- (1 ,1 ,3-trimethyl-2.3-dihydro-1 H-inden-4-yl)pyridin-3-carboxamid, 5-Methoxy-2-methyl- 4-(2-{[({(1 E)-1 -[3-(trifluormethyl)phenyl]ethyliden}amino)oxy]methyl}phenyl)-2,4- dihydro-3H-1 ,2,4-triazol-3-on, 2-Methyl-{2-[({cyclopropyl[(4-methoxyphenyl)- imino]methyl}sulfanyl)methyl]phenyl}-3-methoxyacrylat, N-(3-Ethyl-3,5.5- trimethylcyclohexyl)-3-(formylamino)-2-hydroxybenzamid und entsprechende Salze; Picoxystrobin, trifioxystrobin, (2E) -2- (2 - {[6- (3-chloro-2-methylphenoxy) -5-fluoropyrimidin-4-yl] oxy} phenyl) -2- (methoxyimino) -N-methylethanamide, (2E) -2- (ethoxyimino) -N-methyl-2- (2 - {[({(1E) -1 - [3- (trifluoromethyl) phenyl] ethylidene} amino) oxy] methyl} phenyl) ethanamide and corresponding salts, (2E) - 2- (methoxyimino) -N-methyl-2- {2 - [(E) - ({1- [3- (trifluoromethyl) phenyl] ethoxy} - imino) methyl] phenyl} ethanamide, (2E) -2- {2 - [({[(1 E) -1 - (3 - {[(E) -1-fluoro-2-phenylethenyl] oxy} phenyl) ethylidene] amino} oxy) methyl] phenyl} -2- (methoxyimino) -N-methylethaneamide, (2E) -2- {2 - [({[(2E, 3E) -4- (2,6-dichlorophenyl) but-3-en-2-ylidene ] amino} oxy) methyl] phenyl} -2- (methoxyimino) -N-methylethanamide, 2-chloro-N- (1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl) pyridine 3-carboxamide, 5-methoxy-2-methyl-4- (2 - {[({(1 E) -1 - [3- (trifluoromethyl) phenyl] ethylidene} amino) oxy] methyl} phenyl) -2,4 dihydro-3H-1, 2,4-triazol-3-one, 2-methyl {2 - [({cyclopropyl [(4-methoxyphenyl) imino] methyl} sulfanyl) methyl] phenyl} -3-methoxyacrylate, N- (3-ethyl-3,5. 5-trimethylcyclohexyl) -3- (formylamino) -2-hydroxybenzamide and corresponding salts;
F5) Entkoppler, z. B. Dinocap, Fluazinam; F5) decoupler, z. Dinocap, fluazinam;
F6) Inhibitoren der ATP Produktion, z. B. Fentinacetat, Fentinchlorid, Fentinhydroxid, Silthiofam F6) inhibitors of ATP production, e.g. Fentin acetate, fentin chloride, fentin hydroxide, silthiofam
F7) Inhibitoren der Aminosäure- und Proteinbiosynthese, z.B. Andoprim, Blasticidin-S, Cyprodinil, Kasugamycin, Kasugamycinhydrochlorid Hydrat, Mepanipyrim, F7) inhibitors of amino acid and protein biosynthesis, e.g. Andoprim, blasticidin-S, cyprodinil, kasugamycin, kasugamycin hydrochloride hydrate, mepanipyrim,
Pyrimethanil pyrimethanil
F8) Inhibitoren der Signal-Transduktion, z. B. Fenpiclonil, Fludioxonil, Quinoxyfen F8) inhibitors of signal transduction, e.g. Fenpiclonil, fludioxonil, quinoxyfen
F9) Inhibitoren der Fett- und Membran Synthese, z. B. Chlozolinat, Iprodion, F9) inhibitors of fat and membrane synthesis, e.g. B. chlozolinate, iprodione,
Procymidon, Vinclozolin, Ampropylfos, Kalium-Ampropylfos, Edifenphos, Iprobenfos (IBP), Isoprothiolan, Pyrazophos, Tolclofos-methyl, Biphenyl, lodocarb, Propamocarb, Propamocarb hydrochlorid Procymidone, Vinclozolin, Ampropylfos, Potassium-Ampropylfos, Edifenphos, Iprobenfos (IBP), Isoprothiolane, Pyrazophos, Tolclofos-methyl, Biphenyl, iodocarb, Propamocarb, Propamocarb hydrochloride
F10) Inhibitoren der Ergosterol Biosynthese, z. B. Fenhexamid, Azaconazol, Bitertanol, Bromuconazol, Diclobutrazol, Difenoconazol, Diniconazol, Diniconazol-M, Etaconazol, Fenbuconazol, Fluquinconazol, Flusilazol, Flutriafol, Furconazol, Furconazol-cis, Hexaconazol, Imibenconazol, Ipconazol, Metconazol, Myclobutanil, Paclobutrazol, Penconazol, Propiconazol, Prothioconazol, Simeconazol, Spiroxamin, Tebuconazol, Triadimefon, Triadimenol, Triticonazol, Uniconazol, Voriconazol, Imazalil, F10) inhibitors of ergosterol biosynthesis, eg. Fenhexamid, azaconazole, bitertanol, bromuconazole, diclobutrazole, difenoconazole, diniconazole, diniconazole-M, etaconazole, Fenbuconazole, fluquinconazole, flusilazole, flutriafol, furconazole, furconazole-cis, hexaconazole, imibenconazole, ipconazole, metconazole, myclobutanil, paclobutrazole, penconazole, propiconazole, prothioconazole, simeconazole, spiroxamine, tebuconazole, triadimefon, triadimol, triticonazole, uniconazole, voriconazole, imazalil,
Imazalilsulfat, Oxpoconazol, Fenarimol, Flurprimidol, Nuarimol, Pyrifenox, Triforin, Pefurazoat, Prochloraz, Triflumizol, Viniconazol, Aldimorph, Dodemorph, Imazalil sulfate, oxpoconazole, fenarimol, flurprimidol, nuarimol, pyrifenox, triforin, pefurazoate, prochloraz, triflumizole, viniconazole, aldimorph, dodemorph,
Dodemorphacetat, Fenpropimorph, Tridemorph, Fenpropidin, Naftifin, Pyributicarb, Terbinafin, 1 -(4-Chlorophenyl)-2-(1 H-1 ,2,4-triazol-1 -yl)cycloheptanol, Methyl-1 -(2.2- dimethyl-2.3-dihydro-1 H-inden-1 -yl)-1 H-imidazol-5-carboxylat, N'-{5-(Difluormethyl)-2- methyl-4-[3-(trimethyl-silyl)propox N-Ethyl- N-methyl-N'-{2-meihyl-5-(trifluormethyl)-4-[3-Dodemorphoacetate, fenpropimorph, tridemorph, fenpropidin, naftifine, pyributicarb, terbinafine, 1- (4-chlorophenyl) -2- (1H-1, 2,4-triazol-1-yl) cycloheptanol, methyl-1 - (2.2-dimethyl -2,3-dihydro-1H-inden-1-yl) -1H-imidazole-5-carboxylate, N '- {5- (difluoromethyl) -2-methyl-4- [3- (trimethyl-silyl) -propox N Ethyl-N-methyl-N '- {2-methyl-5- (trifluoromethyl) -4- [3-
(trimethylsilyl)propoxy]phenyl}imidoformamid und 0-{1 -[(4-Methoxy-phenoxy)methyl]-(trimethylsilyl) propoxy] phenyl} imidoformamide and 0- {1 - [(4-methoxyphenoxy) methyl] -
2,2-dimeihylpropyl}-1 H-imidazol-1 -carbothioat; F1 1 ) Inhibitoren der Zellwand Synthese, z. B. Benthiavalicarb, Bialaphos, 2,2-dimethylhexyl-1-H-imidazole-1-carbothioate; F1 1) inhibitors of cell wall synthesis, e.g. Benthiavalicarb, Bialaphos,
Dimethomorph, Flumorph, Iprovalicarb, Polyoxins, Polyoxorim, Validamycin A  Dimethomorph, flumorph, iprovalicarb, polyoxins, polyoxorim, validamycin A
F12) Inhibitoren der Melanin Biosynthese, z. B. Capropamid, Diclocymet, Fenoxanil, Phtalid, Pyroquilon, Tricyclazol F12) inhibitors of melanin biosynthesis, e.g. Capropamide, diclocymet, fenoxanil, phtalid, pyroquilon, tricyclazole
F13) Resistenzinduktion, z. B. Acibenzolar-S-methyl, Probenazol, Tiadinil F13) resistance induction, e.g. Acibenzolar-S-methyl, probenazole, tiadinil
F14) Multisite, z. B. Captafol, Captan, Chlorothalonii, Kupfersalze wie: Kupferhydroxid, Kupfernaphthenat, Kupferoxychlorid, Kupfersulfat, Kupferoxid, Oxin-Kupfer und Bordeaux Mischung, Dichlofluanid, Dithianon, Dodin, Dodin freie Base, Ferbam, Folpet, Fluorofolpet, Guazatin, Guazatinacetat, Iminoctadin, Iminoctadinalbesilat, Iminoctadintriacetat, Mankupfer, Mancozeb, Maneb, Metiram, Metiram Zink, Propineb, Schwefel und Schwefelpräparate enthaltend Calciumpolysulphid, Thiram, Tolylfluanid, Zineb, Ziram F14) Multisite, z. B. captafol, captan, chlorothalonii, copper salts such as: copper hydroxide, copper naphthenate, copper oxychloride, copper sulfate, copper oxide, oxine-copper and Bordeaux mixture, dichlofluanid, dithianon, dodin, dodine free base, Ferbam, folpet, fluorofolpet, guazatine, guazatin acetate, iminoctadine, Iminoctadinalesilate, iminoctadine triacetate, mancopper, mancozeb, maneb, metiram, metiram zinc, propineb, sulfur and sulfur preparations containing calcium polysulphide, thiram, tolylfluanid, zineb, ziram
F15) Unbekannter Mechanismus, z. B. Amibromdol, Benthiazol, Bethoxazin, F15) Unknown mechanism, e.g. Amibromdole, benthiazole, bethoxazine,
Capsimycin, Carvon, Chinomethionat, Chloropicrin, Cufraneb, Cyfiufenamid, Capsimycin, carvone, quinomethionate, chloropicrin, cufraneb, cyfiufenamid,
Cymoxanil, Dazomet, Debacarb, Diclomezine, Dichlorophen, Dicloran, Difenzoquat, Difenzoquat Methylsulphat, Diphenylamin, Ethaboxam, Ferimzon, flumetover, Flusulfamid, Fluopicolid, Fluoroimid, Fosatyl-Al, Hexachlorobenzol, 8-Hydroxy- chinolinsulfat, Iprodione, Irumamycin, Isotianil, Methasulphocarb, etrafenon, Methyl Isothiocyanat, Mildiomycin, Natamycin, Nickel dimethyldithiocarbamat, Nitrothal- isopropyl, Octhilinon, Oxamocarb, Oxyfenthiin, Pentachlorophenol und Salze, 2- Phenylphenol und Salze, Piperalin, Propanosin -Natrium, Proquinazid, Pyrrolnitrin, Quintozen, Tecloftalam, Tecnazen, Triazoxid, Trichlamid, Zarilamid und 2,3.5,6- Tetrachlor-4-(methylsulfonyl)-pyridin, N-(4-Chlor-2-nitrophenyl)-N-ethyl-4-methyl- benzenesulfonamid, 2-Amino-4-methyl-N-phenyl-5-thiazolecarboxamid, 2-Chlor-N- (2,3-dihydro-1 ,1 ,3-trimethyl-1 H-inden-4-yl)-3-pyridincarboxamid, 3-[5-(4-Chlorphenyl)- 2,3-dimethylisoxazolidin-3-yl]pyridin, cis-1 -(4-Chlorphenyl)-2-(1 H-1 ,2,4-triazol-1 -yl)- cycloheptanol, 2,4-Dihydro-5-methoxy-2-methyl-4-[[[[1 -[3-(trifluoromethyl)-phenyl]- ethyliden]-amino]-oxy]-methyl]-phenyl]-3H-1 ,2.3-triazol-3-on (185336-79-2), Methyl 1 - (2,3-dihydro-2.2-dimethyl-1 H-inden-1 -yl)-1 H-imidazole-5-carboxylat, 3,4.5-Trichlor-2,6- pyridindicarbonitril, Methyl 2-[[[cyclopropyl[(4-methoxyphenyl) Cymoxanil, Dazomet, Debacarb, Diclomezine, Dichlorophene, Dicloran, Difenzoquat, Difenzoquat Methylsulphate, Diphenylamine, Ethaboxam, Ferimzone, Flumetover, Flusulfamide, fluopicolide, fluoroimide, fosatyl-Al, hexachlorobenzene, 8-hydroxyquinoline sulfate, iprodione, irumamycin, isotianil, methasulphocarb, etrafenone, methyl isothiocyanate, mildiomycin, natamycin, nickel dimethyldithiocarbamate, nitrothal isopropyl, octhilinone, oxamocarb, oxyfenthiine, pentachlorophenol and Salts, 2-phenylphenol and salts, piperaline, propanosine sodium, proquinazide, pyrroline nitrine, quintozene, tecloftalam, tecnazene, triazoxide, trichlamide, zarilamide and 2,3,5,6-tetrachloro-4- (methylsulfonyl) -pyridine, N- (4 -Chloro-2-nitrophenyl) -N-ethyl-4-methyl-benzenesulfonamide, 2-amino-4-methyl-N-phenyl-5-thiazolecarboxamide, 2-chloro-N- (2,3-dihydro-1, 1 , 3-trimethyl-1H-inden-4-yl) -3-pyridinecarboxamide, 3- [5- (4-chlorophenyl) -2,3-dimethylisoxazolidin-3-yl] pyridine, cis-1 - (4-chlorophenyl ) -2- (1H-1,2,4-triazol-1-yl) -cycloheptanol, 2,4-dihydro-5-methoxy-2-methyl-4 - [[[[1 - [3- (trifluoromethyl ) -phenyl] -ethylidene] -amino] -oxy] -methyl] -phenyl] -3H-1,2,3-triazol-3-one (185336-79-2), methyl 1 - (2,3-dihydro-2,2-dimethyl-1H-inden-1-yl) -1H-imidazole-5-carboxylate, 3,4,5-trichloro-2,6-pyridinedicarbonitrile, methyl 2 - [[[cyclopropyl [(4-methoxyphenyl)
imino]methyl]thio]methyl]-. alpha. -(methoxymethylen)- benzacetat, 4-Chlor-alpha- propinyloxy-N-[2-[3-methoxy-4-(2-propinyloxy)phenyl]ethyl]-benzacetamide, (2S)-N-[2- [4-[[3-(4-chlorophenyl)-2-propinyl]oxy]-3-methoxyphenyl]ethyl]-3-methyl-2-[(methyl- sulfonyl)amino]-butanamid, 5-Chlor-7-(4-methylpiperidin-1-yl)-6-(2.4,6-trifluorophenyl)- [1 ,2,4]triazolo[1 ,5-a]pyrimidin, 5-Chlor-6-(2,4.6-trifluorophenyl)-N-[(1 R)-1 .2.2-trimethyl- propyl][1 .2,4]triazolo[1 .5-a]pyrimidin-7-amin, 5-Chlor-N-[(1 R)-1 ,2-dimethylpropyl]-6- (2,4,6-trifluorophenyl) [1 .2,4]triazolo[1 ,5-a]pyrimidin-7-amine, N-[1 -(5-Brom-3-chloro- pyhdin-2-yl)ethyl]-2,4-dichloronicotinamid, N-(5-Brom-3-chlorpyridin-2-yl)methyl-2.4- dichlornicotinamid, 2-Butoxy-6-iod-3-propyl-benzopyranon-4-on, N-{(Z)-[(cyclopropyl- methoxy) imino][6-(difluormethoxy)-2,3-difluorphenyl]methyl}-2-benzacetamid, N-(3- Ethyl-3,5,5-trimethyl-cyclohexyl)-3-formylamino-2-hydroxy-benzamid, 2-[[[[1 -[3(1 Fluor- 2-phenylethyl)oxy] phenyl] ethyliden]amino]oxy]methyl]-alpha-(methoxyimino)-N- methyl-alphaE-benzacetamid, N-{2-[3-Chlor-5-(trifluormethyl)pyridin-2-yl]ethyl}-2- (trifluoromethyl)benzamid, N-(3'.4'-dichlor-5-fluorbiphenyl-2-yl)-3-(difluormethyl)-1 - methyl-1 H-pyrazol-4-carboxamid, N-(6-Methoxy-3-pyridinyl)-cyclopropan carboxamid, 1 -[(4-Methoxyphenoxy)methyl]-2,2-dimethylpropyl-1 H-imidazol-1 -carbonsäure, 0-[1 - [(4-Methoxyphenoxy)methyl]-2,2-dimethylpropyl]-1 H-imidazol-1 - carbothioic acid, 2-(2- {[6-(3-Chlor-2-methylphenoxy)-5-fluorpyrirnidin-4-yl]oxy}phenyl)-2-(methoxyimino)-N- methylacetamid Bakterizide: imino] methyl] thio] methyl] -. alpha. - (methoxymethylene) - benzoacetate, 4-chloro-alpha-propynyloxy-N- [2- [3-methoxy-4- (2-propynyloxy) phenyl] ethyl] -benzacetamide, (2S) -N- [2- [4 - [[3- (4-chlorophenyl) -2-propynyl] oxy] -3-methoxyphenyl] ethyl] -3-methyl-2 - [(methylsulfonyl) amino] butanamide, 5-chloro-7- (4 -methylpiperidin-1-yl) -6- (2,4,6-trifluorophenyl) - [1,2,4] triazolo [1,5-a] pyrimidine, 5-chloro-6- (2,4,6-trifluorophenyl) -N [(1R) -1,2,2-trimethyl-propyl] [1,2,4] triazolo [1 .5-a] pyrimidin-7-amine, 5-chloro-N - [(1R) -1, 2-dimethylpropyl] -6- (2,4,6-trifluorophenyl) [1, 2,4] triazolo [1,5-a] pyrimidin-7-amine, N- [1- (5-bromo-3-chloro - pyhyn-2-yl) ethyl] -2,4-dichloronicotinamide, N- (5-bromo-3-chloropyridin-2-yl) methyl-2,4-dichloronotinamide, 2-butoxy-6-iodo-3-propyl-benzopyranone -4-one, N - {(Z) - [(cyclopropylmethoxy) imino] [6- (difluoromethoxy) -2,3-difluorophenyl] methyl} -2-benzacetamide, N- (3-ethyl-3,5 , 5-trimethylcyclohexyl) -3-formylamino-2-hydroxybenzamide, 2 - [[[[1 - [3 (1-fluoro-2-phenylethyl) oxy] phenyl] ethylidene] amino] oxy] methyl] -alpha - (methoxyimino) -N-methyl-alphaE-benzacetamide, N- {2- [3-chloro-5- (trifluoromethyl) pyridin-2-yl] ethyl} -2- (trifluoromethyl) benzamide, N- (3'.4'-dichloro 5-fluorobiphenyl-2-yl) -3- (difluoromethyl) -1-methyl-1H-pyrazole-4-carboxamide, N- (6-methoxy-3-pyridinyl) -cyclopropane carboxamide, 1 - [(4- Methoxyphenoxy) methyl] -2,2-dimethylpropyl-1H-imidazole-1-carboxylic acid, 0- [1 - [(4-methoxyphenoxy) methyl] -2,2-dimethylpropyl] -1H-imidazole-1-carbothioic acid , 2- (2- {[6- (3-Chloro-2-methylphenoxy) -5-fluoropyrirnidin-4-yl] oxy} phenyl) -2- (methoxyimino) -N-methylacetamide bactericides:
Bronopol, Dichlorophen, Nitrapyrin, Nickel-Dimethyldithiocarbamat, Kasugamycin, Octhiiinon, Furancarbonsäure, Oxytetracyclin, Probenazol, Streptomycin, Tecloftalam, Kupfersulfat und andere Kupfer-Zubereitungen. Bronopol, dichlorophen, nitrapyrin, nickel dimethyldithiocarbamate, kasugamycin, octhiiinone, furancarboxylic acid, oxytetracycline, probenazole, streptomycin, tecloftalam, copper sulfate and other copper preparations.
Insektizide / Akarizide / Nematizide: 11 ) Acetylcholinesterase (AChE) Inhibitoren, wie beispielsweise Carbamate, z.B. Insecticides / acaricides / nematicides: 11) Acetylcholinesterase (AChE) inhibitors such as carbamates, e.g.
Alanycarb, Aldicarb, Bendiocarb, Benfuracarb, Butocarboxim, Butoxycarboxim, Carb- aryl, Carbofuran, Carbosulfan, Ethiofencarb, Fenobucarb, Formetanate, Furathiocarb, Isoprocarb, Methiocarb, Methomyl, etolcarb, Oxamyl, Pirimicarb, Propoxur, Thio- dicarb, Thiofanox, Triazamate, Trimethacarb, XMC und Xylylcarb; oder  Alanycarb, aldicarb, bendiocarb, benfuracarb, butocarboxime, butoxycarboxim, carbarnyl, carbofuran, carbosulfan, ethiofencarb, fenobucarb, formetanate, furathiocarb, isoprocarb, methiocarb, methomyl, etolcarb, oxamyl, pirimicarb, propoxur, thiodicarb, thiofanox, triazamates, Trimethacarb, XMC and xylylcarb; or
Organophosphate, z.B. Acephate, Azamethiphos, Azinphos (-methyl, -ethyl), Organophosphates, e.g. Acephates, azamethiphos, azinphos (-methyl, -ethyl),
Cadusafos, Chlorethoxyfos, Chlorfenvinphos, Chlormephos, Chlorpyrifos (-methyl), Coumaphos, Cyanophos, Demeton-S-methyl, Diazinon, Dichlorvos/DDVP,  Cadusafos, Chlorethoxyfos, Chlorfenvinphos, Chlormephos, Chlorpyrifos (-methyl), Coumaphos, Cyanophos, Demeton-S-methyl, Diazinone, Dichlorvos / DDVP,
Dicrotophos, Dimethoate, Dimethylvinphos, Disulfoton, EPN, Ethion, Ethoprophos, Famphur, Fenamiphos, Fenitrothion, Fenthion, Fosthiazate, Heptenophos, Isofenphos, Isopropyl O(methoxyaminothio-phosphoryl) salicylat, Isoxathion, Malathion, Me- carbam, Methamidophos, Methidathion, Mevinphos, Monocrotophos, Naled, Dicrotophos, dimethoates, dimethylvinphos, disulphoton, EPN, Ethion, Ethoprophos, Famphur, Fenamiphos, Fenitrothion, Fenthion, Fosthiazate, Heptenophos, Isofenphos, Isopropyl O (methoxyaminothio-phosphoryl) salicylate, Isoxathion, Malathion, Me-carbam, Methamidophos, Methidathion, Mevinphos , Monocrotophos, Naled,
Omethoate, Oxydemeton-methyl, Parathion (-methyl), Phenthoate, Phorate, Omethoate, Oxydemeton-methyl, Parathion (-methyl), Phenthoate, Phorate,
Phosalone, Phosmet, Phosphamidon, Phoxim, Pirimiphos (-methyl), Profenofos, Pro- petamphos, Prothiofos, Pyraclofos, Pyridaphenthion, Quinalphos, Sulfotep, Phosalone, Phosmet, Phosphamidone, Phoxim, Pirimiphos (-methyl), Profenofos, Propetamphos, Prothiofos, Pyraclofos, Pyridaphenthion, Quinalphos, Sulfotep,
Tebupirimfos, Temephos, Terbufos, Tetrachlorvinphos, Thiometon, Triazophos, Triclorfon und Vamidothion. Tebupirimfos, Temephos, Terbufos, Tetrachlorvinphos, Thiometone, Triazophos, Triclorfon and Vamidothion.
12) GABA-gesteuerte Chlorid-Kanal-Antagonisten, wie beispielsweise Organochlorine, z.B. Chlordane und Endosulfan (alpha-); oder Fiprole (Phenylpyrazole), z.B. Ethiprole, Fipronil, Pyrafluprole und Pyriprole. 12) GABA-controlled chloride channel antagonists, such as organochlorines, e.g. Chlordane and endosulfan (alpha); or fiproles (phenylpyrazoles), e.g. Ethiprole, Fipronil, Pyrafluprole and Pyriprole.
13) Natrium-Kanal-Modulatoren / Spannungsabhängige Natrium-Kanal-Blocker, wie beispielsweise Pyrethroide, z.B. Acrinathrin, Allethrin (d-cis-trans, d-trans), Bifenthrin, Bioallethrin, Bioallethrin-S-cyclopentenyl, Bioresmethrin, Cycloprothrin, Cyfluthrin (beta-), Cyhalothrin (gamma-, lambda-), Cypermethrin (alpha-, beta-, theta-, zeta-), Cy- phenothrin [(1 R)-irans-lsomere], Deltamethrin, Dimefluthrin, Empenthrin [(EZ)-(1 R)- Isomere], Esfenvalerate, Etofenprox, Fenpropathrin, Fenvalerate, Flucythrinate, Flu- methrin, Fluvalinate (tau-), Halfenprox, Imiprothrin, etofluthrin, Permethrin, Pheno- thrin [(I R)-trans-lsomer], Prallethrin, Profi uthrin, Pyrethrine (pyrethrum), Resmethrin, RU 1 5525, Silafluofen, Teil uthrin, Tetra methrin [(1 R)- Isomere], Tralomethrin, 13) Sodium channel modulators / voltage dependent sodium channel blockers such as pyrethroids, eg acrinathrin, allethrin (d-cis-trans, d-trans), bifenthrin, bioallethrin, bioallethrin-S-cyclopentenyl, bioresmethrin, cycloprothrin, cyfluthrin (beta-), cyhalothrin (gamma, lambda), cypermethrin (alpha-, beta-, theta-, zeta-), cychenothrin [(1R) -irans-isomers], deltamethrin, dimefluthrin, empenthrin [( EZ) - (1R) - isomers], esfenvalerates, etofenprox, fenpropathrin, fenvalerates, flucythrinates, flumethrin, fluvalinates (tau-), halfenprox, imiprothrin, etofluthrin, permethrin, phenothrin [(IR) -trans-isomer ], Prallethrin, prouthrin, pyrethrin (pyrethrum), resmethrin, RU 1 5525, silafluofen, part of uthrin, tetra methrin [(1R) - isomer], tralomethrin,
Transfluthrin und ZXI 8901 ; oder_DDT; oder Methoxychlor. Transfluthrin and ZXI 8901; oder_DDT; or methoxychlor.
14) Nikotinerge Acetylcholin-Rezeptor-Agonisten, wie beispielsweise Neonikotinoide, z.B. Acetamiprid, Clothianidin, Dinotefuran, Imidacloprid, Nitenpyram, Thiacloprid,14) nicotinergic acetylcholine receptor agonists such as neonicotinoids, e.g. Acetamiprid, clothianidin, dinotefuran, imidacloprid, nitenpyram, thiacloprid,
Thiamethoxam; oder Nikotin. thiamethoxam; or nicotine.
15) Allosterische Acetylcholin-Rezeptor-Modulatoren (Agonisten), wie beispielsweise Spinosyne, z.B. Spinetoram und Spinosad. 15) Allosteric acetylcholine receptor modulators (agonists), such as spinosyns, e.g. Spinetoram and spinosad.
16) Chlorid-Kanal-Aktivatoren, wie beispielsweise Avermectine/Milbemycine, z.B. 16) chloride channel activators, such as avermectins / milbemycins, e.g.
Abamectin, Emamectin, Emamectin-benzoate, Lepimectin und Milbemectin. Abamectin, Emamectin, Emamectin benzoate, Lepimectin and Milbemectin.
17) Juvenilhormon-Analoge, z.B. Hydroprene, Kinoprene, Methoprene; oder 17) Juvenile hormone analogs, e.g. Hydroprene, kinoprene, methoprene; or
Fenoxycarb; Pyriproxyfen. fenoxycarb; Pyriproxyfen.
18) Wirkstoffe mit unbekannten oder nicht spezifischen Wirkmechanismen, wie beispielsweise Begasungsmittel, z. B. Methyibromid und andere Alkylhalogenide; oder Chloropicrin; Sulfurylfluorid; Borax; Brechweinstein. 18) active substances with unknown or non-specific mechanisms of action, such as fumigants, z. Methyl bromide and other alkyl halides; or chloropicrin; sulfuryl fluoride; Borax; Tartar emetic.
19) Selektive Fraßhemmer, z.B. Pymetrozine; oder Flonicamid. 19) Selective feeding inhibitors, e.g. pymetrozine; or flonicamide.
110) Milbenwachstumsinhibitoren, z.B. Clofentezine, Diflovidazin, Hexythiazox, Etoxazole. 110) mite growth inhibitors, e.g. Clofentezine, diflovidazine, hexythiazox, etoxazole.
11 1 ) Mikrobielle Disruptoren der Insektendarmmembran, wie beispielsweise Bacillus thunngiensis Subspezies israelensis, Bacillus sphaericus, Bacillus thunngiensis Subspezies aizawai, Bacillus thunngiensis Subspezies kurstaki, Bacillus thunngiensis Subspezies tenebrionis, und BT-Pflanzen-Proteine, z.B. Cry1 Ab, Cry1 Ac, Cry1 Fa, Cry2Ab, mCry3A, Cry3Ab, Cry3Bb, Cry34/35Ab1 . 11 1) Microbial disruptors of insect intestinal membrane, such as Bacillus thunngiensis subspecies israelensis, Bacillus sphaericus, Bacillus thunngiensis subspecies aizawai, Bacillus thunngiensis subspecies kurstaki, Bacillus thunngiensis Subspecies tenebrionis, and BT plant proteins, eg Cry1 Ab, Cry1 Ac, Cry1 Fa, Cry2Ab, mCry3A, Cry3Ab, Cry3Bb, Cry34 / 35Ab1.
112) Inhibitoren der oxidativen Phosphorylierung, ATP-Disruptoren, wie beispielsweise Diafenthiuron; oder Organozinnverbindungen, z.B. Azocyclotin, Cyhexatin, Fenbutatin oxide; oder Propargite; Tetradifon. 112) inhibitors of oxidative phosphorylation, ATP disruptors such as diafenthiuron; or organotin compounds, e.g. Azocyclotine, cyhexatin, fenbutatin oxide; or propargite; Tetradifon.
113) Entkoppler der oxidativen Phoshorylierung durch Unterbrechung des H-Proton- gradienten, wie beispielsweise Chlorfenapyr und DNOC. 113) Decoupling of oxidative phosphorylation by interruption of the H proton gradient, such as chlorfenapyr and DNOC.
114) Nikotinerge Acetylcholin-Rezeptor-Antagonisten, wie beispielsweise Bensultap, Cartap (-Hydrochlorid), Thiocyclam, und Thiosultap (-sodium). 114) nicotinergic acetylcholine receptor antagonists, such as Bensultap, Cartap (hydrochloride), thiocyclam, and thiosultap (-sodium).
115) Inhibitoren der Chitinbiosynthese, Typ 0, wie beispielsweise Benzoylharnstoffe, z.B. Bistrifluron, Chlorfluazuron, Diflubenzuron, Flucycloxuron, Flufenoxuron,115) inhibitors of chitin biosynthesis, type 0, such as benzoylureas, e.g. Bistrifluron, chlorofluorazuron, diflubenzuron, flucycloxuron, flufenoxuron,
Hexafiumuron, Lufenuron, Novaluron, Noviflumuron, Teflubenzuron und Triflumuron. Hexafiumuron, Lufenuron, Novaluron, Noviflumuron, Teflubenzuron and Triflumuron.
116) Inhibitoren der Chitinbiosynthese, Typ 1 , wie beispielsweise Buprofezin. 117) Häutungsstörende Wirkstoffe, wie beispielsweise Cyromazine. 116) inhibitors of chitin biosynthesis, type 1, such as buprofezin. 117) Moisture-disrupting agents, such as cyromazines.
118) Ecdysonagonisten/-disruptoren, wie beispielsweise Diacylhydrazine, z.B. 118) ecdysone agonists / disruptors such as diacylhydrazines, e.g.
Chromafenozide, Halofenozide, Methoxyfenozide und Tebufenozide. 119) Oktopaminerge Agonisten, wie beispielsweise Amitraz. Chromafenozide, Halofenozide, Methoxyfenozide and Tebufenozide. 119) Octopaminergic agonists, such as amitraz.
I20) Komplex-Ii I-Elektronentransportinhibitoren, wie beispielsweise Hydramethylnon; Acequinocyl; Fluacrypyrim. 121 ) Komplex-I-Elektronentransportinhibitoren, beispielsweise aus der Gruppe der METI-Akarizide, z.B. Fenazaquin, Fenpyroximate, Pyrimidifen, Pyridaben, Tebufen- pyrad, Tolfenpyrad; oder Rotenone (Derris). I20) complex Ii I electron transport inhibitors such as, for example, hydramethylnone; acequinocyl; Fluacrypyrim. 121) Complex I electron transport inhibitors, for example from the group of the METI acaricides, e.g. Fenazaquin, Fenpyroximate, Pyrimidifen, Pyridaben, Tebufenpyrad, Tolfenpyrad; or Rotenone (Derris).
I22) Spannungsabhängige Natriumkanal-Blocker, z.B. Indoxacarb; Metaflumizone. 123) Inhibitoren der Acetyl-CoA-Carboxylase, wie beispielsweise Tetronsäure-Derivate, z.B. Spirodiclofen und Spiromesifen; oder Tetramsäure-Derivate, z.B. Spirotetramat. 124) Komplex-IV-Elektronentransportinhibitoren, wie beispielsweise Phosphine, z.B. Aluminiumphosphid, Kalziumphosphid, Phosphin, Zinkphosphid; oder Cyanid. I22) Voltage-dependent sodium channel blockers, eg indoxacarb; Metaflumizone. 123) inhibitors of acetyl-CoA carboxylase, such as tetronic acid derivatives, eg spirodiclofen and spiromesifen; or tetramic acid derivatives, eg spirotetramat. 124) complex IV electron transport inhibitors, such as phosphines, eg, aluminum phosphide, calcium phosphide, phosphine, zinc phosphide; or cyanide.
125) Komplex-Il-Elektronentransportinhibitoren, wie beispielsweise Cyenopyrafen. I26) Ry a n od i n reze pto r- Eff e kto re n , wie beispielsweise Diamide, z.B. Flubendiamide, Chiorantraniiiprole (Rynaxypyr), Cyantraniliprole (Cyazypyr) sowie 3-Brom-N-{2-brom- 4-chlor-6-[(1 -cyclopropylethyl)carbamoyl]phenyl}-1 -(3-chlorpyridin-2-yl)-1 H-pyrazol-5- carboxamid (bekannt aus WO2005/077934) oder Methyl-2-[3.5-dibrom-2-({[3-brom-1 - (3-chSorpyridin-2-yl)-1 H-pyrazol-5-yl]carbonyl}amino)benzoyl]-1 ,2- dimethylhydrazincarboxy-lat (bekannt aus WO2007/043677). 125) Complex II electron transport inhibitors, such as cyenopyrafen. I26) Ry a n ore reze pto r eff ects, such as diamides, e.g. Flubendiamide, Chiorantraniiprole (Rynaxypyr), Cyantraniliprole (Cyazypyr) and 3-bromo-N- {2-bromo-4-chloro-6 - [(1-cyclopropylethyl) carbamoyl] phenyl} -1 - (3-chloropyridin-2-yl ) -1 H -pyrazole-5-carboxamide (known from WO2005 / 077934) or methyl 2- [3,5-dibromo-2 - ({[3-bromo-1 - (3-chSorpyridin-2-yl) -1H -pyrazol-5-yl] carbonyl} amino) benzoyl] -1, 2-dimethylhydrazinecarboxylate (known from WO2007 / 043677).
Weitere Wirkstoffe mit unbekanntem Wirkmechanismus, wie beispielsweise Other drugs with unknown mechanism of action, such as
Azadirachtin, Amidoflumet, Benzoximate, Bifenazate, Chinomethionat, Cryolite, Cyflumetofen, Dicofol, 5-chloro-2-[(3,4,4-trifluorobut-3-en-1 -yl)sulfonyl]-1 ,3-thiazol, Flu- fenerim, Pyridalyl und Pyrifluquinazon; desweiteren Präparate auf Basis von Bacillus firmus (1-1582, BioNeem, Votivo) sowie folgende bekannte wirksame Verbindungen 4- {[(6-Brompyrid-3-yl)methyl](2-fluorethyl)amino}furan-2(5H)-on (bekannt aus WO 2007/1 15644), 4-{[(6-Fluorpyrid-3-yl)methyl](2,2-difluorethyl)amino}furan-2(5H)-on (bekannt aus WO 2007/1 15644), 4-{[(2-Chlor-1 .3-thiazol-5-yl)methyl](2- fluorethyl)amino}furan-2(5H)-on (bekannt aus WO 2007/1 15644), 4-{[(6-Chlorpyrid-3- yl)methyl](2-fluorethyl)amino}furan-2(5H)-on (bekannt aus WO 2007/1 15644), 4-{[(6- Chlorpyrid-3-yl)methyl](2,2-difluorethyl)amino}furan-2(5H)-on (bekannt aus WO Azadirachtin, amidoflumet, benzoximate, bifenazate, quinomethionate, cryolite, cyflumetofen, dicofol, 5-chloro-2 - [(3,4,4-trifluorobut-3-en-1-yl) sulfonyl] -1, 3-thiazole, Flu - fenerim, pyralidyl and pyrifluquinazone; furthermore preparations based on Bacillus firmus (1-1582, BioNeem, Votivo) and the following known active compounds 4- {[(6-bromopyrid-3-yl) methyl] (2-fluoroethyl) amino} furan-2 (5H) - on (known from WO 2007/1 15644), 4 - {[(6-fluoropyrid-3-yl) methyl] (2,2-difluoroethyl) amino} furan-2 (5H) -one (known from WO 2007/1 15644), 4 - {[(2-chloro-1 .3-thiazol-5-yl) methyl] (2-fluoroethyl) amino} furan-2 (5H) -one (known from WO 2007/1 15644), 4 - {[(6-chloropyrid-3-yl) methyl] (2-fluoroethyl) amino} furan-2 (5H) -one (known from WO 2007/1 15644), 4 - {[(6-chloropyrid-3-ol) yl) methyl] (2,2-difluoroethyl) amino} furan-2 (5H) -one (known from WO
2007/1 15644), 4-{[(6-Chlor-5-fluorpyrid-3-yl)methyl](methyl)amino}furan-2(5H)-on (bekannt aus WO 2007/1 15643), 4-{[(5,6-Dichlorpyrid-3-yl)methyl](2- fluorethyl)amino}furan-2(5H)-on (bekannt aus WO 2007/1 15646), 4-{[(6-Chlor-5- fluorpyrid-3-yl)methyl](cyclopropyl)amino}furan-2(5H)-on (bekannt aus WO 2007/1 15644), 4 - {[(6-chloro-5-fluoropyrid-3-yl) methyl] (methyl) amino} furan-2 (5H) -one (known from WO 2007/1 15643), 4- {[(5,6-dichloropyrid-3-yl) methyl] (2-fluoroethyl) amino} furan-2 (5H) -one (known from WO 2007/1 15646), 4 - {[(6-chloro-5 - fluoropyrid-3-yl) methyl] (cyclopropyl) amino} furan-2 (5H) -one (known from WO
2007/1 15643), 4-{[(6-Chlorpyrid-3-yl)methyl](cyclopropyl)amino}furan-2(5H)-on 2007/1 15643), 4 - {[(6-chloropyrid-3-yl) methyl] (cyclopropyl) amino} furan-2 (5H) -one
(bekannt aus EP0539588), 4-{[(6-Chlorpyrid-3-yl)methyl](methyl)amino}furan-2(5H)-on (bekannt aus EP0539588), [1 -(6-Chlorpyridin-3-yl)ethyl](methyl)oxido-A4- sulfanylidencyanamid (bekannt aus WO 2007/149134) und seine Diastereomere {[(1 f?)-1 -(6-Chlorpyridin-3-yl)ethyl](methyl)oxido- .6-sulfanyliden}cyanamid und {[(1 S)-1 - (6-Chlorpyridin-3-yl)ethyl](methyl)oxido- .6-sulfanyliden}cyanamid (ebenfalls bekannt aus WO 2007/149134) sowie Sulfoxaflor (ebenfalls bekannt aus WO 2007/149134), 1 - [2-fluoro-4-methyl-5-[(2!2,2-t fluoroethyl)sulfinyl]phenyl]-3-(trifluoromethyl)-1 H-1 ,2,4- Triazol-5-amine (bekannt aus WO 2006/043635), [(3S,4aR,12R,12aS,12ßS)-3- [(Cyclopropylcarbonyl)oxy]-6,12-dihydroxy-4,12b-dimethyl-1 1-oxo-9-(pyridin-3-yl)- 1 ,3,4,4a,5.6,6a, 12.12a,12ß-decahydro-2H,1 1 H-benzo[f]pyrano[4,3-b]chromen-4- yl]methylcyclopropancarboxylat (bekannt aus WO 2006/129714), 2-Cyano-3- (difluormethoxy)-N,N-dimethylbenzolsulfonamid (bekannt aus WO2006/056433), 2- Cyano-3-(difluormethoxy)-N-methylbenzolsulfonamid (bekannt aus WO2006/100288), 2-Cyano-3-(difluormethoxy)-N-ethylbenzolsulfonamid (bekannt aus WO2005/035486), 4-(Difluormethoxy)-N-ethyl-N-methyl-1 ,2-benzothiazol-3-amin-1 ,1 -dioxid (bekannt aus WO2007/057407), N-[1 -(2.3-Dimethylphenyl)-2-(3,5-dimethylphenyl)ethyl]-4.5-dihydro- 1 ,3-thiazol-2-amin (bekannt aus WO2008/104503), {1 '-[(2E)-3-(4-Chlorphenyl)prop-2- en-1 -yl]-5-fluorspiro[indol-3,4'-piperidin]-1 (2H)-yl}(2-chlorpyridin-4-yl)methanon (known from EP0539588), 4 - {[(6-chloropyrid-3-yl) methyl] (methyl) amino} furan-2 (5H) -one (known from EP0539588), [1- (6-chloropyridine-3-) yl) ethyl] (methyl) oxido-A 4 - sulfanylidenecyanoamide (known from WO 2007/149134) and its diastereomers {[(1-f?) - 1- (6-chloropyridin-3-yl) ethyl] (methyl) -oxido-. 6- sulfanylidene} cyanamide and {[(1S) -1- (6-chloropyridin-3-yl) ethyl] (methyl) oxido. 6- sulfanylidene} cyanamide (also known from WO 2007/149134) and sulfoxaflor (also known from WO 2007/149134), 1 - [2-fluoro-4-methyl-5 - [(2 : 2,2-t-fluoroethyl) sulfinyl] phenyl] -3- (trifluoromethyl) -1H-1, 2,4-triazole-5-amine (known from WO 2006/043635), [(3S, 4aR, 12R, 12aS, 12ßS) -3- [ (Cyclopropylcarbonyl) oxy] -6,12-dihydroxy-4,12b-dimethyl-1 1-oxo-9- (pyridin-3-yl) -1,4,4,4a, 5.6,6a, 12.12a, 12β- decahydro-2H, 1 H-benzo [f] pyrano [4,3-b] chromen-4-yl] methylcyclopropanecarboxylate (known from WO 2006/129714), 2-cyano-3- (difluoromethoxy) -N, N- dimethylbenzenesulfonamide (known from WO2006 / 056433), 2-cyano-3- (difluoromethoxy) -N-methylbenzenesulfonamide (known from WO2006 / 100288), 2-cyano-3- (difluoromethoxy) -N-ethylbenzenesulfonamide (known from WO2005 / 035486) , 4- (Difluoromethoxy) -N-ethyl-N-methyl-1,2-benzothiazol-3-amine-1,1-dioxide (known from WO2007 / 057407), N- [1- (2,3-dimethylphenyl) -2 - (3,5-dimethylphenyl) ethyl] -4,5-dihydro-1,3-thiazol-2-amine (known from WO2008 / 104503), {1 '- [(2E) -3 - (4-chlorophenyl) prop-2-en-1-yl] -5-fluorospiro [indole-3,4'-piperidin] -1 (2H) -yl} (2-chloropyridin-4-yl) -methanone
(bekannt aus WO2003106457), 3-(2,5-Dimethylphenyl)-4-hydroxy-8-methoxy-1 .8- diazaspiro[4.5]dec-3-en-2-on (bekannt aus WO2009049851 ), 3-(2,5-Dimethylphenyl)- 8-methoxy-2-oxo-1 ,8-diazaspiro[4.5]dec-3-en-4-yl-ethylcarbonat (bekannt aus (known from WO2003106457), 3- (2,5-dimethylphenyl) -4-hydroxy-8-methoxy-1, 8-diazaspiro [4.5] dec-3-en-2-one (known from WO2009049851), 3- ( 2,5-dimethylphenyl) - 8-methoxy-2-oxo-1,8-diazaspiro [4.5] dec-3-en-4-yl-ethyl carbonate (known from
WO2009049851 ), 4-(But-2-in-1 -yloxy)-6-(3,5-dimethylpiperidin-1 -yl)-5-fluorpyrimidin (bekannt aus WO2004099160), (2,2,3,3.4,4.5,5-Octafluorpentyl)(3,3.3- trifluorpropyl)malononitril (bekannt aus WO2005063094), (2.2.3,3.4,4.5.5- Octafluorpentyl)(3.3.4.4,4-pentafluorbutyl)malononitril (bekannt aus WO2005063094), 8-[2-(Cyclopropylmethoxy)-4-(trifluormethyl)phenoxy]-3-[6-(trifluormethyl)pyridazin-3- yl]-3-azabicyclo[3.2.1 ]octan (bekannt aus WO2007040280 / 282), 2-Ethy!-7-methoxy-3- methyl-6-[(2,2.3,3-tetrafluor-2,3-dihydro-1 ,4-benzodioxin-6-yl)oxy]chinolin-4-yl- methylcarbonat (bekannt aus JP20081 10953), 2-Ethyl-7-methoxy-3-methyl-6-[(2.2.3.3- tetrafluor-2.3-dihydro-1 ,4-benzodioxin-6-yl)oxy]chinolin-4-ylacetat (bekannt aus JP20081 10953), PF1364 (Chemical Abstracts Nr 1204776-60-2, bekannt aus WO2009049851), 4- (but-2-yn-1-ylxy) -6- (3,5-dimethylpiperidin-1-yl) -5-fluoropyrimidine (known from WO2004099160), (2,2,3,3,4,4.5 , 5-octafluoropentyl) (3,3,3-trifluoropropyl) malononitrile (known from WO2005063094), (2.2.3,3.4,4,5,5-octafluoropentyl) (3.3.4.4,4-pentafluorobutyl) malononitrile (known from WO2005063094), 8- [2- (Cyclopropylmethoxy) -4- (trifluoromethyl) phenoxy] -3- [6- (trifluoromethyl) pyridazin-3-yl] -3-azabicyclo [3.2.1] octane (known from WO2007040280 / 282), 2-ethyl ! -7-methoxy-3-methyl-6 - [(2,2,3,3-tetrafluoro-2,3-dihydro-1,4-benzodioxin-6-yl) oxy] quinolin-4-ylmethyl carbonate (known from JP20081 10953), 2-ethyl-7-methoxy-3-methyl-6 - [(2,2,3,3-tetrafluoro-2,3-dihydro-1,4-benzodioxin-6-yl) oxy] quinolin-4-yl acetate (known from JP20081 10953), PF1364 (Chemical Abstracts No. 1204776-60-2, known from
JP2010018586), 5-[5-(3,5-Dichlorphenyl)-5-(trifluormethyl)-4.5-dihydro-1 .2-oxazol-3- yl]-2-(1 H-1 ,2.4-triazol-1 -yl)benzonitril (bekannt aus WO2007075459), 5-[5-(2- Chlorpyridin-4-yl)-5-(trifluormethyl)-4,5-dihydro-1 .2-oxazol-3-yl]-2-(1 H-1 ,2,4-triazoM - yl)benzonitril (bekannt aus WO2007075459), 4-[5-(3.5-Dichlorphenyl)-5- (trifluormethyl)-4,5-dihydro-1 ,2-oxazol-3-yl]-2-methyl-N-{2-oxo-2-[(2,2,2- trifluorethyl)amino]ethyl}benzamid (bekannt aus WO2005085216). JP2010018586), 5- [5- (3,5-dichlorophenyl) -5- (trifluoromethyl) -4,5-dihydro-1, 2-oxazol-3-yl] -2- (1H-1, 2,4-triazole-1 -yl) benzonitrile (known from WO2007075459), 5- [5- (2-chloropyridin-4-yl) -5- (trifluoromethyl) -4,5-dihydro-1, 2-oxazol-3-yl] -2- (1H-1, 2,4-triazoM-yl) benzonitrile (known from WO2007075459), 4- [5- (3,5-dichlorophenyl) -5- (trifluoromethyl) -4,5-dihydro-1,2-oxazol-3-yl] -2-methyl-N- {2-oxo-2 - [(2,2,2-trifluoroethyl) amino] ethyl} benzamide ( known from WO2005085216).
Safener sind vorzugsweise ausgewählt aus der Gruppe bestehend aus: Safeners are preferably selected from the group consisting of:
Verbindungen der Formel (S1 ), wobei die Symbole und Indizes folgende Bedeutungen haben: Compounds of the formula (S1), where the symbols and indices have the following meanings:
ΠΑ ist eine natürliche Zahl von 0 bis 5, vorzugsweise 0 bis 3; ΠΑ is a natural number from 0 to 5, preferably 0 to 3;
RA1 ist Halogen, (CrC4)Alkyl, (d-C4)Alkoxy, Nitro oder (d-C4)Haloalkyl; RA 1 is halogen, (C 1 -C 4 ) alkyl, (C 1 -C 4 ) alkoxy, nitro or (C 1 -C 4 ) haloalkyl;
WA ist ein unsubstituierter oder substituierter divalenter heterocyclischer Rest aus der Gruppe der teilungesättigten oder aromatischen Fünfring-Heterocyclen mit 1 bis 3 Heteroringatomen aus der Gruppe N und O, wobei mindestens ein N-Atom und höchstens ein O-Atom im Ring enthalten ist, vorzugsweise ein Rest aus der Gruppe WA is an unsubstituted or substituted divalent heterocyclic radical selected from the group consisting of the monounsaturated or aromatic five-membered heterocycles having 1 to 3 hetero ring atoms from the group N and O, where at least one N atom and at most one O atom are present in the ring, preferably one Rest of the group
ITIA ist 0 oder 1 ; ITIA is 0 or 1;
RA2 ist ORA3, SRA3 oder N RA3RA4 oder ein gesättigter oder ungesättigter 3- bis 7- gliedriger Heterocyclus mit mindestens einem N-Atom und bis zu 3 Heteroatomen, vorzugsweise aus der Gruppe O und S, der über das N-Atom mit der Carbonylgruppe in (S1 ) verbunden ist und unsubstituiert oder durch Reste aus der Gruppe (Ci-C4)Alkyl, (Ci-C4)Alkoxy oder gegebenenfalls substituiertes Phenyl substituiert ist, vorzugsweise ein Rest der Formel ORA3, N H RA4 oder N(CH3)2, insbesondere der Formel ORA3; RA3 ist Wasserstoff oder ein unsubstituierter oder substituierter aliphatischer Kohlenwasserstoffrest, vorzugsweise mit insgesamt 1 bis 18 C- Atomen; RA 2 is ORA 3 , SRA 3 or N RA 3 RA 4 or a saturated or unsaturated 3- to 7-membered heterocycle having at least one N atom and up to 3 heteroatoms, preferably from the group O and S, via the N Atom is bonded to the carbonyl group in (S1) and is unsubstituted or substituted by radicals from the group (C 1 -C 4 ) alkyl, (C 1 -C 4 ) alkoxy or optionally substituted phenyl, preferably a radical of the formula ORA 3 , NH RA 4 or N (CH 3) 2, in particular of the formula ORA 3 ; RA 3 is hydrogen or an unsubstituted or substituted aliphatic hydrocarbon radical, preferably having a total of 1 to 18 carbon atoms;
RA4 ist Wasserstoff, (Ci-C6)Alkyl, (Ci-Cr Alkoxy oder substituiertes oder RA 4 is hydrogen, (Ci-C6) alkyl, (Ci-Cr alkoxy or substituted or
unsubstituiertes Phenyl; unsubstituted phenyl;
RA 5 ist H, (Ci-C8)Alkyl, (CrC8)Haloalkyl, (Ci-C4)Alkoxy(Ci-C8)Alkyl, Cyano oder COORA9, worin RA 9 Wasserstoff, (Ci-C8)Alkyl, (Ci-Cs)Haloalkyl, (Ci-C4)Alkoxy- (Ci-C4)alkyl, (CrC6)Hydroxyalkyl, (C3-Ci2)Cycloalkyl oder Tri-(Ci-C4)-alkyl-silyl ist; RA6, RA7, RA8 sind gleich oder verschieden Wasserstoff, (Ci-C8)Alkyl, (Ci-C8)Haloalkyl, (C3- Ci2)Cycloalkyl oder substituiertes oder unsubstituiertes Phenyl; vorzugsweise: R A 5 is H, (C 1 -C 8 ) alkyl, (C 1 -C 8 ) haloalkyl, (C 1 -C 4 ) alkoxy (C 1 -C 8 ) alkyl, cyano or COORA 9 , where R A 9 is hydrogen, (C 1 -C 4 ) 8) alkyl, (Ci-Cs) -haloalkyl, (Ci-C 4) alkoxy (Ci-C 4) alkyl, (CrC 6) hydroxyalkyl, (C3-Ci2) -cycloalkyl or tri- (Ci-C 4) -alkyl-silyl; RA 6 , RA 7 , RA 8 are identical or different hydrogen, (C 1 -C 8 ) alkyl, (C 1 -C 8 ) haloalkyl, (C 3 -C 12) cycloalkyl or substituted or unsubstituted phenyl; preferably:
a) Verbindungen vom Typ der Dichlorphenylpyrazolin-3-carbonsäure (S1 a), vorzugsweise Verbindungen wie 1 -(2,4-Dichlorphenyl)-5-(ethoxycarbonyl)-5-methyl- 2- pyrazolin-3-carbonsäure, 1 -(2,4-Dichlorphenyl)-5-(ethoxycarbonyl)-5-methyl-2- pyrazolin-3-carbonsäureethylester (S1 -1 ) ("Mefenpyr-diethyl"), und verwandte Verbindungen, wie sie in der WO-A-91 /07874 beschrieben sind; a) compounds of the type of dichlorophenylpyrazoline-3-carboxylic acid (S1 a ), preferably compounds such as 1- (2,4-dichlorophenyl) -5- (ethoxycarbonyl) -5-methyl-2-pyrazoline-3-carboxylic acid, 1 - ( 2,4-dichlorophenyl) -5- (ethoxycarbonyl) -5-methyl-2-pyrazoline-3-carboxylic acid ethyl ester (S1 -1) ("mefenpyr-diethyl"), and related compounds as described in WO-A-91 / 07874;
b) Derivate der Dichlorphenylpyrazolcarbonsäure (S1 b), vorzugsweise Verbindungen wie 1 -(2,4-Dichlorphenyl)-5-methyl-pyrazol-3-carbonsäureethylester (S1 -2), 1 -(2,4-Di-chlorphenyl)-5-isopropyl-pyrazol-3-carbonsäureethylester (S1 -3), b) dichlorophenylpyrazolecarboxylic acid derivatives (S1 b), preferably compounds such as 1 - (2,4-dichlorophenyl) -5-methyl-pyrazole-3-carboxylate (S1 -2), 1 - (2,4-dichlorophenyl) - Ethyl 5-isopropyl-pyrazole-3-carboxylate (S1-3),
1 -(2,4-Dichlor-phenyl)-5-(1 .1 -dimethyl-ethyl)pyrazol-3-carbonsäureethyl-ester (S1 -4) und verwandte Verbindungen, wie sie in EP-A-333 131 und EP-A-269 806  Ethyl 1 - (2,4-dichloro-phenyl) -5- (1, 1-dimethyl-ethyl) -pyrazole-3-carboxylate (S1 -4) and related compounds as described in EP-A-333 131 and EP -A-269 806
beschrieben sind; are described;
c) Derivate der 1 ,5-Diphenylpyrazol-3-carbonsäure (S1 C), vorzugsweise Ver- bindungen wie 1 -(2,4-Dichlorphenyl)-5-phenylpyrazol-3-carbonsäureethylester (S1 -5), 1 -(2-Chlorphenyl)-5-phenylpyrazol-3-carbonsäuremethylester (S1 -6) und verwandte Verbindungen wie sie beispielsweise in der EP-A-268554 beschrieben sind; c) derivatives of 1, 5-diphenylpyrazole-3-carboxylic acid (S1 C), preferably comparison compounds such as 1 - (2,4-dichlorophenyl) -5-phenylpyrazole-3-carboxylate (S1 -5), 1 - (2 -Chlorophenyl) -5-phenylpyrazole-3-carboxylic acid methyl ester (S1 -6) and related compounds as described, for example, in EP-A-268554;
d) Verbindungen vom Typ der Triazolcarbonsäuren (S1 d), vorzugsweise d) compounds of the type of the triazolecarboxylic acids (S1 d ), preferably
Verbindungen wie Fenchlorazol(-ethylester), d.h. Compounds such as fenchlorazole (ethyl ester), i.
1 -(2,4-Dichlorphenyl)-5-trichlormethyl-(1 H)-1 ,2,4-triazol-3-carbonsäureethylester (S1 -7). und verwandte Verbindungen wie sie in EP-A-174 562 und EP-A-346 620 beschrieben sind; 1- (2,4-dichlorophenyl) -5-trichloromethyl- (1 H) -1, 2,4-triazole-3-carboxylic acid ethyl ester (S1 -7). and related compounds as described in EP-A-174 562 and EP-A-346 620;
e) Verbindungen vom Typ der 5-Benzyl- oder 5-Phenyl-2-isoxazolin-3- carbonsäure oder der 5,5-Diphenyl-2-isoxazolin-3-carbonsäure (S1 e), vorzugsweise Ver- bindungen wie 5-(2,4-Dichlorbenzyl)-2-isoxazolin-3-carbonsäureethylester (S1 -8) oder 5-Phenyl-2-isoxazolin-3-carbonsäureethylester (S1 -9) und verwandte Verbindungen, wie sie in WO-A-91 /08202 beschrieben sind, bzw. 5,5-Diphenyl-2-isoxazolin-3- carbonsäure (S1 -1 0) oder 5,5-Diphenyi-2-isoxazolin-3-carbonsäureethylester (S1 -1 1 ) ("Isoxadifen-ethyl") oder -n-propylester (S1 -12) oder der 5-(4-Fluorphenyi)-5-phenyi-2- isoxazolin-3-carbonsäureethylester (S1 -13), wie sie in der Patentanmeldung e) Compounds of the 5-benzyl- or carboxylic acid-5-phenyl-2-isoxazoline-3 or the 5,5-diphenyl-2-isoxazoline-3-carboxylic acid (S1 s), preferably comparison compounds such as ethyl 5- (2,4-dichlorobenzyl) -2-isoxazoline-3-carboxylate (S1 -8) or ethyl 5-phenyl-2-isoxazoline-3-carboxylate (S1 -9) and related compounds as described in Or 5,5-diphenyl-2-isoxazoline-3-carboxylic acid (S1 -10) or ethyl 5,5-diphenyl-2-isoxazoline-3-carboxylate (S1-1 1) ( "Isoxadifen-ethyl") or n-propyl ester (S1 -12) or 5- (4-fluorophenyl) -5-phenyi-2-isoxazoline-3-carboxylic acid ethyl ester (S1 -13), as described in the patent application
WO-A-95/07897 beschrieben sind. WO-A-95/07897 are described.
S2) Chinolinderivate der Formel (S2), S2) quinoline derivatives of the formula (S2)
wobei die Symbole und Indizes folgende Bedeutungen haben: where the symbols and indices have the following meanings:
RB1 ist Halogen, (CrC4)Alkyl, (d-C4)Alkoxy, Nitro oder (Ci-C )Haloalkyl; RB 1 is halogen, (C 1 -C 4 ) alkyl, (C 1 -C 4 ) alkoxy, nitro or (C 1 -C 4 ) haloalkyl;
ΠΒ ist eine natürliche Zahl von 0 bis 5, vorzugsweise 0 bis 3; ΠΒ is a natural number from 0 to 5, preferably 0 to 3;
RB 2 ist ORB 3, SRb 3 oder N RB 3RB4 oder ein gesättigter R B 2 is OR B 3 , SR b 3 or NR B 3 RB 4 or a saturated one
oder ungesättigter 3- bis 7-gliedriger Heterocyclus mit mindestens einem N-Atom und bis zu 3 Heteroatomen, vorzugsweise aus der Gruppe O und S, der über das N-Atom mit der Carbonyigruppe in (S2) verbunden ist und unsubstituiert oder durch Reste aus der Gruppe (Ci-C4)Alkyl, (Ci-C4)Alkoxy oder gegebenenfalls substituiertes Phenyl substituiert ist, vorzugsweise ein Rest der Formel ORB3, N H RB4 oder N(CH3)2, insbesondere der Formel ORB3; or unsaturated 3- to 7-membered heterocycle having at least one N-atom and up to 3 heteroatoms, preferably from the group O and S, which is connected via the N-atom with the Carbonyigruppe in (S2) and unsubstituted or by radicals the group is substituted (Ci-C 4 ) alkyl, (Ci-C 4 ) alkoxy or optionally substituted phenyl, preferably a radical of the formula ORB 3 , NH RB 4 or N (CH 3) 2, in particular of the formula ORB 3 ;
RB3 ist Wasserstoff oder ein unsubstituierter oder substituierter aliphatischer Kohlenwasserstoffrest, vorzugsweise mit insgesamt 1 bis 18 C-Atomen; RB 3 is hydrogen or an unsubstituted or substituted aliphatic hydrocarbon radical, preferably having a total of 1 to 18 C atoms;
RB4 ist Wasserstoff, (Ci-CeJAlkyl, (Ci-Cr,)Alkoxy oder substituiertes oder RB 4 is hydrogen, (Ci-CeJAlkyl, (Ci-Cr,) alkoxy or substituted or
unsubstituiertes Phenyl; unsubstituted phenyl;
TB ist eine (Ci oder C2)-Alkandiylkette, die unsubstituiert oder mit einem oder zwei (Ci-C4)Alkylresten oder mit [(Ci-C3)-Alkoxy]-carbonyl substituiert ist; vorzugsweise: a) Verbindungen vom Typ der 8-Chinolinoxyessigsäure (S2a), vorzugsweise (5-Chlor-8-chinolinoxy)essigsäure-(1 -methylhexyl)ester ("Cloquintocet-mexyl") (S2-1 ), (5-Chlor-8-chinolinoxy)essigsäure-(1 ,3-dimethyl-but-1-yl)ester (S2-2), TB is a (Ci or C2) alkanediyl chain which is unsubstituted or substituted by one or two (Ci-C 4 ) alkyl radicals or by [(Ci-C3) alkoxy] carbonyl; preferably: a) Compounds of the 8-quinolinoxyacetic acid (S2 a), preferably (5-chloro-8-quinolinoxy) acetic acid (1 -methylhexyl) ester ( "cloquintocet-mexyl") (S2-1), (5-chloro- 8-quinolinoxy) acetic acid (1, 3-dimethylbut-1-yl) ester (S2-2),
(5-Chlor-8-chinolinoxy)essigsäure-4-allyloxy-butylester (S2-3), (5-Chlor-8-chinolin- oxy)essigsäure-1 -allyloxy-prop-2-ylester (S2-4), (5-Chlor-8-chinolinoxy)essigsäure- ethylester (S2-5), (5-Chlor-8-chinolinoxy)essigsäuremethylester (S2-6), (5-Chlor-8- chinolinoxy)essigsäureallylester (S2-7), (5-Chlor-8-chinolinoxy)essigsäure-2-(2- propyliden-iminoxy)-1 -ethylester (S2-8), (5-Chlor-8-chinolinoxy)essigsäure-2-oxo-prop- 1 -ylester (S2-9) und verwandte Verbindungen, wie sie in EP-A-86 750, EP-A-94 349 und EP-A-191 736 oder EP-A-0 492 366 beschrieben sind, sowie (5-Chlor-8- chinolinoxy)essigsäure (S2-10), deren Hydrate und Salze, beispielsweise deren Lithium-, Natrium- Kalium-, Kalzium-, Magnesium-, Aluminium-, Eisen-, Ammonium-, quartäre Ammonium-, Sulfonium-, oder Phosphoniumsalze wie sie in der WO-A- 2002/34048 beschrieben sind; (5-Chloro-8-quinolinoxy) acetic acid 4-allyloxy-butyl ester (S2-3), (5-chloro-8-quinolinoxy) -acetic acid 1 -allyloxy-prop-2-yl ester (S2-4), (5-chloro-8-quinolinoxy) acetic acid ethyl ester (S2-5), (5-chloro-8-quinolinoxy) acetic acid methyl ester (S2-6), (5-chloro-8-quinolinoxy) allyl acetate (S2-7), (5-Chloro-8-quinolinoxy) acetic acid 2- (2-propylidene-iminoxy) -1-ethyl ester (S2-8), (5-chloro-8-quinolinoxy) -acetic acid 2-oxo-prop-1-yl-ester (S2-9) and related compounds as described in EP-A-86,750, EP-A-94,349 and EP-A-191,736 or EP-A-0 492 366, as well as (5-chloro-8 - quinolinoxy) acetic acid (S2-10), their hydrates and salts, for example their lithium, sodium, potassium, calcium, magnesium, aluminum, iron, ammonium, quaternary ammonium, sulfonium or phosphonium salts, such as they are described in WO-A-2002/34048;
b) Verbindungen vom Typ der (5-Chlor-8-chinolinoxy)malonsäure (S2b), vorzugsweise Verbindungen wie (5-Chlor-8-chinolinoxy)malonsäurediethylester, (5-Chlor- 8-chinolinoxy)malonsäurediallylester, b) compounds of the (5-chloro-8-quinolinoxy) malonic acid type (S2 b ), preferably compounds such as diethyl (5-chloro-8-quinolinoxy) malonate, (5-chloro-8-quinolinoxy) malonic acid diallyl ester,
(5-Chlor-8-chinolinoxy)malonsäure-methyl-ethylester und verwandte Verbindungen, wie sie in EP-A-0 582 198 beschrieben sind.  (5-chloro-8-quinolinoxy) malonic acid methyl ethyl ester and related compounds as described in EP-A-0 582 198.
S3) Verbindungen der Formel (S3) S3) compounds of the formula (S3)
wobei die Symbole und Indizes folgende Bedeutungen haben: Rc1 ist (Ci-C4)Alkyl, (d-C4)Haloalkyl, (C2-C4)Alkenyl, (C2-C4)Haloalkenyl, where the symbols and indices have the following meanings: Rc 1 is (Ci-C 4) alkyl, (dC 4) haloalkyl, (C 2 -C 4) alkenyl, (C 2 -C 4) haloalkenyl,
(C3-C7)Cycloalkyl, vorzugsweise Dichlormethyl; (C3-C7) cycloalkyl, preferably dichloromethyl;
Rc2, Rc3 sind gleich oder verschieden Wasserstoff, (d-C4)Alkyl, (C2-C4)Alkenyl, (C2-C4)Alkinyl, (Ci-C4)Haloalkyl, (C2-C4)Haloalkenyl, (Ci-C4)Alkylcarbamoyl- (Ci-C4)alkyl, (C2-C4)Alkenylcarbamoyl-(CrC4)alkyl, (Ci-C4)Alkoxy-(Ci-C4)alkyl, Dioxolanyl-(Ci-C4)alkyl, Thiazolyl, Furyl, Furylalkyl, Thienyl, Piperidyl, substituiertes oder unsubstituiertes Phenyl, oder Rc2 und Rc3 bilden zusammen einen substituierten oder unsubstituierten heterocyclischen Ring, vorzugsweise einen Oxazolidin-, Rc 2, rc 3 are identical or different hydrogen, (dC 4) alkyl, (C2-C4) alkenyl, (C 2 -C 4) alkynyl, (Ci-C 4) haloalkyl, (C 2 -C 4) haloalkenyl , (Ci-C 4) alkylcarbamoyl (Ci-C4) alkyl, (C 2 -C 4) Alkenylcarbamoyl- (CrC 4) alkyl, (Ci-C 4) alkoxy (Ci-C 4) alkyl, dioxolanyl (C 1 -C 4 ) alkyl, thiazolyl, furyl, furylalkyl, thienyl, piperidyl, substituted or unsubstituted phenyl, or Rc 2 and Rc 3 together form a substituted or unsubstituted heterocyclic ring, preferably an oxazolidine,
Thiazolidin-, Piperidin-, Morpholin-, Hexahydropyrimidin- oder Benzoxazinring; Thiazolidine, piperidine, morpholine, hexahydropyrimidine or benzoxazine ring;
vorzugsweise: Wirkstoffe vom Typ der Dichloracetamide, die häufig als preferably: active substances of the dichloroacetamide type, often as
Vorauflaufsafener (bodenwirksame Safener) angewendet werden, wie z. B. Pre-emergence safeners (soil-active safeners) are applied, such. B.
"Dichiormid" (N.N-Diallyl-2,2-dichloracetamid) (S3-1 ), "R-29148" (3-Dichloracetyl-2,2,5- trimethyl-1 ,3-oxazolidin) der Firma Stauffer (S3-2), "R-28725" (3-Dichloracetyl-2,2,- dimethyl-1 ,3-oxazolidin) der Firma Stauffer (S3-3), "Benoxacor" (4-Dichloracetyl-3,4- dihydro-3-methyl-2H-1 .4-benzoxazin) (S3-4), "PPG-1292" (N-Allyl-N-[(1 ,3-dioxolan-2- yl)-methyl]-dichloracetamid) der Firma PPG Industries (S3-5), "DKA-24" (N-Allyl-N- [(allylaminocarbonyl)methyl]-dichloracetamid) der Firma Sagro-Chem (S3-6), "AD-67" oder "MON 4660" (3-Dichloracetyl-1-oxa-3-aza-spiro[4.5]decan) der Firma Nitrokemia bzw. Monsanto (S3-7), "TI-35" (1 -Dichloracetyl-azepan) der Firma TRI-Chemical RT (S3-8), "Diclonon" (Dicyclonon) oder "BAS145138" oder "LAB145138" (S3-9) ((RS)-1 - Dichloracetyl-3,3,8a-trimethylperhydropyrrolo[1 ,2-a]pyrimidin-6-on) der Firma BASF, "Furilazol" oder "MON 13900" ((RS)-3-Dichloracetyl-5-(2-furyl)-2,2-dimethyloxazolidin) (S3-10); sowie dessen (R)-Isomer (S3-1 1 ).  "Dichiormide" (NN-diallyl-2,2-dichloroacetamide) (S3-1), "R-29148" (3-dichloroacetyl-2,2,5-trimethyl-1,3-oxazolidine) from Stauffer (S3- 2), "R-28725" (3-dichloroacetyl-2,2-dimethyl-1,3-oxazolidine) from Stauffer (S3-3), "Benoxacor" (4-dichloroacetyl-3,4-dihydro-3 -methyl-2H-1, 4-benzoxazine) (S3-4), "PPG-1292" (N-allyl-N - [(1,3-dioxolan-2-yl) -methyl] -dichloroacetamide) from PPG Industries (S3-5), "DKA-24" (N-allyl-N- [(allylaminocarbonyl) methyl] -dichloroacetamide) from Sagro-Chem (S3-6), "AD-67" or "MON 4660" ( 3-dichloroacetyl-1-oxa-3-aza-spiro [4.5] decane) from Nitrokemia or Monsanto (S3-7), "TI-35" (1-dichloroacetyl-azepane) from TRI-Chemical RT (S3 -8), "diclonone" (dicyclonone) or "BAS145138" or "LAB145138" (S3-9) ((RS) -1-dichloroacetyl-3,3,8a-trimethylperhydropyrrolo [1,2-a] pyrimidine-6- on) BASF, "furilazole" or "MON 13900" ((RS) -3-dichloroacetyl-5- (2-furyl) -2,2-dimethyloxazolidine) (S3-10); and its (R) isomer (S3-1 1).
S4) N-Acylsulfonamide der Formel (S4) und ihre Salze, S4) N-acylsulfonamides of the formula (S4) and their salts,
worin die Symbole und Indizes folgende Bedeutungen haben: XD ist CH oder N; wherein the symbols and indices have the following meanings: X D is CH or N;
RD1 ist CO-N RD 5RD6 oder N HCO-RD7; RD 1 is CO-N R D 5 RD 6 or N HCO-RD 7 ;
RD2 ist Halogen, (Ci-C4)Haloalkyl, (d-C4)Haloalkoxy, Nitro, (Ci-C4)Alkyl, RD 2 is halogen, (Ci-C 4) haloalkyl, (dC 4) haloalkoxy, nitro, (Ci-C 4) alkyl,
(Ci-C4)Alkoxy, (d-C4)Alkylsulfonyl, (Ci-C4)Alkoxycarbonyl oder (d-C4)Alkylcarbonyl; RD3 ist Wasserstoff, (Ci-C4)Alkyl, (C2-C4)Alkenyl oder (C2-C4)Alkinyl; RD4 ist Halogen, Nitro, (Ci-C4)Alkyl, (Ci-C4)Haloalkyl, (Ci-C4)Haloalkoxy, (C 1 -C 4 ) alkoxy, (C 1 -C 4 ) alkylsulfonyl, (C 1 -C 4 ) alkoxycarbonyl or (C 1 -C 4 ) -alkylcarbonyl; RD 3 is hydrogen, (C 1 -C 4 ) alkyl, (C 2 -C 4 ) alkenyl or (C 2 -C 4 ) alkynyl; RD 4 is halogen, nitro, (Ci-C 4) alkyl, (Ci-C 4) haloalkyl, (Ci-C 4) haloalkoxy,
(C3-C6)Cycloalkyl, Phenyl, (d-C4)Alkoxy, Cyano, (Ci-C4)Alkylthio, (Ci-C4)Alkylsulfinyl, (d-C4)Alkylsulfonyl, (Ci-C4)Alkoxycarbonyl oder (Ci-C4)Alkylcarbonyl; (C 3 -C 6) cycloalkyl, phenyl, (dC 4) alkoxy, cyano, (Ci-C 4) alkylthio, (Ci-C 4) alkylsulfinyl, (dC 4) alkylsulfonyl, (Ci-C 4) alkoxycarbonyl or ( C 1 -C 4 ) alkylcarbonyl;
RD5 ist Wasserstoff, (Ci-C6)Alkyl, (C3-C6)Cycloalkyl, (C2-C6)Alkenyl, (C2-C6)Alkinyl, (Cs-CeJCycloalkenyl, Phenyl oder 3- bis 6-gliedriges Heterocyclyl enthaltend VD Heteroatome aus der Gruppe Stickstoff, Sauerstoff und Schwefel, wobei die sieben letztgenannten Reste durch VD Substituenten aus der Gruppe Halogen, (d-Cr Alkoxy, (Ci-Ce)Haloalkoxy, (Ci-C2)Alkylsulfinyl, (Ci-C2)Alkylsulfonyl, (C3-C6)Cycloalkyl, (d- C4)Alkoxycarbonyl, (Ci-C4)Alkylcarbonyl und Phenyl und im Falle cyclischer Reste auch (Ci-C4) Alkyl und (Ci-C )Haloalkyl substituiert sind; RD 5 is hydrogen, (Ci-C 6 ) alkyl, (C 3 -C 6 ) cycloalkyl, (C 2 -C 6 ) alkenyl, (C 2 -C 6 ) alkynyl, (Cs-CeJCycloalkenyl, phenyl or 3 bis 6-membered heterocyclyl containing VD heteroatoms from the group consisting of nitrogen, oxygen and sulfur, where the seven latter radicals are represented by VD substituents selected from the group consisting of halogen, (C 1 -C 6 -alkoxy, (C 1 -C 6) -haloalkoxy, (C 1 -C 2 ) -alkylsulfinyl, (Ci-C2) alkylsulfonyl, (C 3 -C 6) cycloalkyl, (d- C4) alkoxycarbonyl, (Ci-C 4) alkylcarbonyl and phenyl and, in the case of cyclic radicals, also (Ci-C4) alkyl and (C -C) haloalkyl are substituted;
RD6 ist Wasserstoff, (Ci-C-6)Alkyl, (C2-Ce)Alkenyl oder (C2-Ce)Alkinyl, wobei die drei letztgenannten Reste durch VD Reste aus der Gruppe Halogen, Hydroxy, (Ci-C4)Alkyl, (d-C4)Alkoxy und (Ci-C4)Alkylthio substituiert sind, oder RD 6 is hydrogen, (C 1 -C 6) alkyl, (C 2 -C 6) alkenyl or (C 2 -C 6) alkynyl, where the last three radicals are represented by VD radicals from the group consisting of halogen, hydroxy, (C 1 -C 4 ) alkyl , (dC 4 ) alkoxy and (Ci-C 4 ) alkylthio are substituted, or
RD5 und RD6 gemeinsam mit dem dem sie tragenden Stickstoffatom einen Pyrrolidinyl- oder Piperidinyl-Rest bilden; RD 5 and RD 6 together with the nitrogen atom carrying them form a pyrrolidinyl or piperidinyl radical;
RD7 ist Wasserstoff, (Ci-C4)Alkylamino, Di-(d-C4)alkylamino, (Ci-Cc)Alkyl, RD 7 is hydrogen, (Ci-C 4 ) alkylamino, di (dC 4 ) alkylamino, (Ci-Cc) alkyl,
(Ca-CeJCycloalkyl, wobei die 2 letztgenannten Reste durch VD Substituenten aus der Gruppe Halogen, (Ci-C4)Alkoxy, (Ci-C6)Haloalkoxy und (Ci-C4)Alkylthio und im Falle cyclischer Reste auch (Ci-C4)Alkyl und (Ci-C4)Haloalkyl substituiert sind; (Ca-CeJCycloalkyl, wherein the latter two radicals by VD substituents selected from the group consisting of halogen, (Ci-C 4 ) alkoxy, (Ci-C6) haloalkoxy and (Ci-C 4 ) alkylthio and in the case of cyclic radicals also (Ci-C 4 ) alkyl and (C 1 -C 4 ) haloalkyl are substituted;
nD ist O, 1 oder 2;n D is O, 1 or 2;
VD ist 0. 1 , 2 oder 3; davon bevorzugt sind Verbindungen vom Typ der N-Acylsulfonamide, z.B. der nachfolgenden Formel (S4a), die z. B. bekannt sind aus WO-A-97/45016 VD is 0. 1, 2 or 3; Of these, preference is given to compounds of the N-acylsulfonamide type, for example of the following formula (S4 a ), which are, for example, B. are known from WO-A-97/45016
worin wherein
RD7 (Ci-Cc)Alkyl, (C3-Cr,)Cycloalkyl, wobei die 2 letztgenannten Reste durch VD Substituenten aus der Gruppe Halogen, (Ci-C4)Alkoxy, (Ci-Ce)Haloalkoxy und (d- C4)Alkylthio und im Falle cyclischer Reste auch (Ci-C4)Alkyl und (Ci-C4)Haloalkyl substituiert sind; RD 7 (Ci-Cc) alkyl, (C3-Cr,) cycloalkyl, where the 2 latter radicals by VD substituents selected from the group consisting of halogen, (Ci-C 4 ) alkoxy, (Ci-Ce) haloalkoxy and (d- C 4 ) alkylthio and in the case of cyclic radicals are also (Ci-C 4 ) alkyl and (Ci-C 4 ) haloalkyl substituted;
RD4 Halogen, (Ci-C4)Alkyl, (CrC4)Alkoxy, CF3; RD 4 is halogen, (C 1 -C 4 ) alkyl, (C 1 -C 4 ) alkoxy, CF 3;
mo 1 oder 2; mo 1 or 2;
VD ist 0, 1 , 2 oder 3 bedeutet; sowie Acylsulfamoyibenzoesaureamide, z.B. der nachfolgenden Formel (S4b), die z.B. bekannt sind aus WO- A-99/ 16744, VD is 0, 1, 2 or 3; and Acylsulfamoyibenzoesaureamide, for example of the formula (S4 b), for example are known from WO-A-99/16744,
z.B. solche worin eg those in which
RD5 = Cyclopropyl und (RD4) = 2-OMe ist ("Cyprosulfamide", S4-1 ), RD 5 = cyclopropyl and (RD 4 ) = 2-OMe ("Cyprosulfamide", S4-1),
RD5 = Cyclopropyl und (RD4) = 5-CI-2-OMe ist (S4-2), RD 5 = cyclopropyl and (RD 4 ) = 5-CI-2-OMe is (S4-2),
RD5 = Ethyl und (RD4) = 2-OMe ist (S4-3), RD 5 = ethyl and (RD 4 ) = 2-OMe is (S4-3),
RD5 = Isopropyl und (RD4) = 5-CI-2-OMe ist (S4-4) und RD 5 = isopropyl and (RD 4 ) = 5-CI-2-OMe is (S4-4) and
RD 5 = Isopropyl und (RD4) = 2-OMe ist (S4-5). sowie Verbindungen vom Typ der N-Acylsulfamoylphenylharnstoffe der Formel (S4C), die z.B. bekannt sind aus der EP-A-365484, R D 5 = isopropyl and (RD 4 ) = 2-OMe is (S4-5). and also compounds of the type of the N-acylsulfamoylphenylureas of the formula (S 4 C ) which are known, for example, from EP-A-365484,
worin wherein
RD8 und RD9 unabhängig voneinander Wasserstoff, (Ci-Cs)Alkyl, (C3-Cs)Cycl RD 8 and RD 9 are independently hydrogen, (Ci-Cs) alkyl, (C3-Cs) cycl
(C3-C6)Alkenyl, (C3-C6)Alkinyl, (C 3 -C 6 ) alkenyl, (C 3 -C 6 ) alkynyl,
RD4 Halogen, (Ci-C4)Alkyl, (Ci-C4)Alkoxy, CF3 RD 4 halogen, (C 1 -C 4 ) alkyl, (C 1 -C 4 ) alkoxy, CF 3
mo 1 oder 2 bedeutet; beispielsweise mo is 1 or 2; for example
1 -[4-(N-2-Methoxybenzoylsulfamoyl)phenyl]-3-methylharnstoff,  1 - [4- (N-2-methoxybenzoylsulfamoyl) phenyl] -3-methylurea,
1 -[4-(N-2-Methoxybenzoylsulfamoyl)phenyl]-3,3-dimethylharnstoff.  1 - [4- (N-2-Methoxybenzoylsulfamoyl) phenyl] -3,3-dimethylurea.
1 -[4-(N-4,5-Dimethylbenzoylsulfamoyl)phenyl]-3-rriethylharnstoff.  1 - [4- (N-4,5-dimethylbenzoylsulfamoyl) phenyl] -3-rriethylurea.
55) Wirkstoffe aus der Klasse der Hydroxyaromaten und der aromatisch- aliphatischen Carbonsäurederivate (S5), z.B. 3,4,5-Triacetoxybenzoesäureethylester, 3.5-Di-methoxy-4-hydroxybenzoesäure, 3,5-Dihydroxybenzoesäure, 4- Hydroxysalicylsäure, 4-Fluorsalicyclsäure, 2-Hydroxyzimtsäure, 2,4-Dichlorzimtsäure, wie sie in der WO-A-2004/084631 , WO-A-2005/015994, WO-A-2005/016001 beschrieben sind. 55) Active ingredients from the class of hydroxyaromatics and aromatic-aliphatic carboxylic acid derivatives (S5), e.g. Ethyl 3,4,5-triacetoxybenzoate, 3,5-dimethoxy-4-hydroxybenzoic acid, 3,5-dihydroxybenzoic acid, 4-hydroxysalicylic acid, 4-fluorosalicyclic acid, 2-hydroxycinnamic acid, 2,4-dichlorocinnamic acid, as described in WO-A- 2004/084631, WO-A-2005/015994, WO-A-2005/016001.
56) Wirkstoffe aus der Klasse der 1 ,2-Dihydrochinoxalin-2-one (S6), z.B. 56) Agents from the class of 1, 2-dihydroquinoxaline-2-ones (S6), e.g.
1 - ethyl-3-(2-thienyl)-1 ,2-dihydrochinoxalin-2-on, 1-Methyl-3-(2-thienyl)-1 ,2-dihydro- chinoxalin-2-thion, 1 -(2-Aminoethyl)-3-(2-thienyl)-1 ,2-dihydro-chinoxalin-2-on-hydro- chlorid, 1-(2-Methylsulfonylaminoethyl)-3-(2-thienyl)-1 ,2-dihydrochinoxa-lin-2-on, wie sie in der WO-A-2005/1 12630 beschrieben sind.  1-ethyl-3- (2-thienyl) -1,2-dihydroquinoxalin-2-one, 1-methyl-3- (2-thienyl) -1,2-dihydroquinoxaline-2-thione, 1- (2 Aminoethyl) -3- (2-thienyl) -1,2-dihydroquinoxalin-2-one hydrochloride, 1- (2-methylsulfonylaminoethyl) -3- (2-thienyl) -1,2-dihydroquinoxa lin-2-one, as described in WO-A-2005/1 12630.
57) Verbindungen der Formel (S7),wie sie in der WO-A-1998/38856 beschrieben 57) Compounds of the formula (S7) as described in WO-A-1998/38856
sind worin die Symbole und Indizes folgende Bedeutungen haben: RE2 sind unabhängig voneinander Halogen, (Ci-C4)Alkyl, (Ci-C4)Alkoxy, are where the symbols and indices have the following meanings: RE 2 are independently halogen, (Ci-C 4) alkyl, (Ci-C 4) alkoxy,
(CrC4)Haloalkyl, (Ci-C4)Alkylamino, Di-(d-C4)Alkylamino, Nitro; (C 1 -C 4 ) haloalkyl, (C 1 -C 4 ) alkylamino, di- (C 1 -C 4 ) alkylamino, nitro;
AE ist COORE3 oder COSRE4 A E is COORE 3 or COSRE 4
RE3, RE4 sind unabhängig voneinander Wasserstoff, (d-C4)Alkyl, (C2-Ce)Alkenyl, (C2-C4)Alkinyl, Cyanoalkyl, (Ci-C4)Haloalkyl, Phenyl, Nitrophenyl, Benzyl, Halobenzyl, Pyridinylalkyl und Alkylammonium, ist 0 oder 1 RE 3 , RE 4 are independently hydrogen, (C 1 -C 4 ) alkyl, (C 2 -C 6) alkenyl, (C 2 -C 4 ) alkynyl, cyanoalkyl, (C 1 -C 4 ) haloalkyl, phenyl, nitrophenyl, benzyl, halobenzyl, pyridinylalkyl and alkyl ammonium, is 0 or 1
E3 sind unabhängig voneinander 0, 1 oder 2, vorzugsweise Diphenyimethoxyessigsaure, Diphenylmethoxyessigsäureethylester, Diphenyl-methoxyessigsäuremethylester (CAS-Reg.Nr. 41858-19-9) (S7-1 ). E 3 are each independently 0, 1 or 2, preferably diphenylmethoxyacetic acid, ethyl diphenylmethoxyacetate, methyl diphenylmethoxyacetate (CAS reference number 41858-19-9) (S7-1).
S8) Verbindungen der Formel (S8),wie sie in der WO-A-98/27049 beschrieben sind S8) compounds of the formula (S8) as described in WO-A-98/27049
Worin Wherein
nF für den Fall, dass ist, eine ganze Zahl von 0 bis 4 und nF in case that is an integer from 0 to 4 and
für den Fall, dass XF=CH ist, eine ganze Zahl von 0 bis 5 ,  for the case that XF = CH, an integer from 0 to 5,
RF1 Halogen, (Ci-C4)Alkyl, (Ci-C4)Haloalkyl, (Ci-C4)Alkoxy, (Ci-C4)Haloalkoxy, Nitro, (Ci-C4)Alkylthio, (Ci-C4)-Alkylsulfonyl, (Ci-C4)Alkoxycarbonyl, ggf. substituiertes. Phenyl, ggf. substituiertes Phenoxy, RF 1 halogen, (C 1 -C 4 ) alkyl, (C 1 -C 4 ) haloalkyl, (C 1 -C 4 ) alkoxy, (C 1 -C 4 ) haloalkoxy, nitro, (C 1 -C 4 ) alkylthio, (C 1 -C 4 ) 4 ) -alkylsulfonyl, (Ci-C 4 ) alkoxycarbonyl, optionally substituted. Phenyl, optionally substituted phenoxy,
RF2 Wasserstoff oder (Ci-C4)Alkyl RF 2 is hydrogen or (Ci-C 4 ) alkyl
RF3 Wasserstoff, (CrC8)Alkyl, (C2-C4)Alkenyl, (C2-C4)Alkinyl, oder Aryl, wobei jeder der vorgenannten C-haltigen Reste unsubstituiert oder durch einen oder mehrere, vorzugsweise bis zu drei gleiche oder verschiedene Reste aus der Gruppe, bestehend aus Halogen und Alkoxy substituiert ist; bedeuten, oder deren Salze, vorzugsweise Verbindungen worin XF CH, RF 3 is hydrogen, (C 1 -C 8 ) alkyl, (C 2 -C 4 ) alkenyl, (C 2 -C 4 ) alkynyl, or aryl, wherein each of the aforementioned C-containing radicals is unsubstituted or substituted by one or more, preferably up to three identical or different radicals from the group consisting of halogen and alkoxy substituted; or their salts, preferably compounds wherein X is F, CH,
nF eine ganze Zahl von 0 bis 2 , nF is an integer from 0 to 2,
RF1 Halogen, (Ci-C4)Alkyl. (d-C4)Haloalkyl, (Ci-C4)Alkoxy, (d-C4)Haloalkoxy, RF2 Wasserstoff oder (Ci-C4)Alkyl, RF 1 halogen, (C 1 -C 4 ) alkyl. (dC 4 ) haloalkyl, (Ci-C 4 ) alkoxy, (dC 4 ) haloalkoxy, RF 2 hydrogen or (Ci-C 4 ) alkyl,
RF3 Wasserstoff, (Ci-C8)Alkyl, (C2-C4)Alkenyl, (C2-C4)Alkinyl, oder Aryl, wobei jeder der vorgenannten C-haltigen Reste unsubstituiert oder durch einen oder mehrere, vorzugsweise bis zu drei gleiche oder verschiedene Reste aus der Gruppe, bestehend aus Halogen und Alkoxy substituiert ist, bedeuten, RF 3 is hydrogen, (C 1 -C 8 ) -alkyl, (C 2 -C 4 ) -alkenyl, (C 2 -C 4 ) -alkynyl, or aryl, where each of the abovementioned C-containing radicals is unsubstituted or substituted by one or more preferably up to three identical or different radicals from the group consisting of halogen and alkoxy substituted, mean
oder deren Salze. S9) Wirkstoffe aus der Klasse der 3-(5-Tetrazolylcarbonyl)-2-chinolone (S9), z.B. 1 ,2-Dihydro-4-hydroxy-1 -ethyl-3-(5-tetrazolylcarbonyl)-2-chinolon (CAS-Reg.Nr. or their salts. S9) Agents from the class of 3- (5-tetrazolylcarbonyl) -2-quinolones (S9), e.g. 1, 2-Dihydro-4-hydroxy-1-ethyl-3- (5-tetrazolylcarbonyl) -2-quinolone (CAS Reg.
219479-18-2), 1 ,2-Dihydro-4-hydroxy-1 -methyl-3-(5-tetrazolyl-carbonyl)-2-chinolon (CAS-Reg.Nr. 95855-00-8), wie sie in der WO-A-1999/000020 beschrieben sind. S10) Verbindungen der Formeln (S10a) oder (S10 ) 219479-18-2), 1, 2-dihydro-4-hydroxy-1-methyl-3- (5-tetrazolyl-carbonyl) -2-quinolone (CAS Reg. 95855-00-8), as described in WO-A-1999/000020. S10) compounds of the formulas (S10 a ) or (S10)
wie sie in der WO-A-2007/023719 und WO-A-2007/023764 beschrieben sind  as described in WO-A-2007/023719 and WO-A-2007/023764
(S10a) (S10b) (S10 a) (S10 b)
worin wherein
RG1 Halogen, (Ci-C4)Alkyl, Methoxy, Nitro, Cyano, CF3, OCF3 RG 1 halogen, (C 1 -C 4 ) alkyl, methoxy, nitro, cyano, CF 3 , OCF 3
YG, ZGunabhängig voneinander O oder S, YG, ZGindependently O or S,
ηβ eine ganze Zahl von 0 bis 4, ηβ is an integer from 0 to 4,
RG2 (Ci-Ci6)Alkyl, (C2-C6)Alkenyl, (C3-C6)Cycloalkyl, Aryl; Benzyl, Halogenbenzyl, RG3 Wasserstoff oder (Ci-Ce)Alkyl bedeutet. RG 2 (C 1 -C 6 ) alkyl, (C 2 -C 6 ) alkenyl, (C 3 -C 6 ) cycloalkyl, aryl; Benzyl, halobenzyl, RG 3 is hydrogen or (Ci-Ce) alkyl.
S1 1 ) Wirkstoffe vom Typ der Oxyimino-Verbindungen (S1 1 ), die als Saatbeizmittel bekannt sind, wie z. B. "Oxabetrinil" ((Z)-1 .3-Dioxolan-2-ylmethoxyimino- (phenyl)acetonitril) (S1 1 -1 ), das als Saatbeiz-Safener für Hirse gegen Schäden von Metolachlor bekannt ist, "Fluxofenim" (1 -(4-Chlorphenyl)-2,2,2-trifluor-1 -ethanon-0- (1 .3-dioxolan-2-ylmethyl)-oxim) (S1 1 -2), das als Saatbeiz-Safener für Hirse gegen Schäden von Metolachlor bekannt ist, und "Cyometrinil" oder "CGA-43089" ((Z)- Cyanomethoxyimino(phenyl)acetonitril) (S1 1 -3), das als Saatbeiz-Safener für Hirse gegen Schäden von Metolachlor bekannt ist. S12) Wirkstoffe aus der Klasse der Isothiochromanone (S12), wie z.B. Methyl-[(3- oxo-1 H-2-benzothiopyran-4(3H)-yliden)methoxy]acetat (CAS-Reg.Nr. 205121 -04-6) (S12-1 ) und verwandte Verbindungen aus WO-A-1998/13361 . S13) Eine oder mehrere Verbindungen aus Gruppe (S13): "Naphthalic anhydrid" (1 ,8-Naphthalindicarbonsäureanhydrid) (S13-1 ), das als Saatbeiz-Safener für Mais gegen Schäden von Thiocarbamatherbiziden bekannt ist, "Fenclorim" (4,6-Dichlor-2- phenylpyrimidin) (S13-2), das als Safener für Pretiiachlor in gesätem Reis bekannt ist, "Flurazole" (Benzyl-2-chlor-4-trifluormethyl-1 ,3-thiazol-5-carboxylat) (S13-3), das als Saatbeiz-Safener für Hirse gegen Schäden von Alachlor und Metolachlor bekannt ist, "CL 304415" (CAS-Reg.Nr. 31541 -57-8) (4-Carboxy-3.4-dihydro-2H-1-benzopyran-4- essigsäure) (S13-4) der Firma American Cyanamid, das als Safener für Mais gegen Schäden von Imidazolinonen bekannt ist, "MG 191 " (CAS-Reg.Nr. 96420-72-3) (2- Dichlormethyl-2-methyl-1 ,3-dioxolan) (S13-5) der Firma Nitrokemia, das als Safener für Mais bekannt ist, "MG-838" (CAS-Reg.Nr. 133993-74-5) (2-propenyl 1-oxa-4- azaspiro[4.5]decan-4-carbodithioat) (S13-6) der Firma Nitrokemia, "Disulfoton" (0,0- Diethyl S-2-ethylthioethyl phosphordithioat) (S13-7), "Dietholate" (0,0-Diethyl-O- phenylphosphorothioat) (S13-8), "Mephenate" (4-Chlorphenyl-methylcarbamat) (S13-9). S1 1) active ingredients of the type of oxyimino compounds (S1 1), which are known as seed dressing, such. "Oxabetrinil" ((Z) -1,3-dioxolan-2-ylmethoxyimino (phenyl) acetonitrile) (S1 1 -1), which is known as a seed safener for millet against damage by metolachlor, "Fluxofenim" ( 1- (4-chlorophenyl) -2,2,2-trifluoro-1-ethanone-O- (1,3-dioxolan-2-ylmethyl) -oxime) (S1 1 -2), which was used as a seed dressing safener for millet is known to be susceptible to damage by metolachlor, and "Cyometrinil" or "CGA-43089" ((Z) - cyanomethoxyimino (phenyl) acetonitrile) (S1 1 -3), which is known as millet safener for millet against damage by metolachlor. S12) active substances from the class of the isothiochromanones (S12), such as, for example, methyl - [(3-oxo-1H-2-benzothiopyran-4 (3H) -ylidene) methoxy] acetate (CAS Reg. No. 205121 -04- 6) (S12-1) and related compounds of WO-A-1998/13361. S13) One or more compounds from group (S13): "naphthalene anhydride" (1,8-naphthalenedicarboxylic anhydride) (S13-1), known as a seed safener for corn against damage by thiocarbamate herbicides, "fenclorim" (4,6 Dichloro-2-phenylpyrimidine) (S13-2), known as safener for pretilachlor in seeded rice, "flurazole" (benzyl-2-chloro-4-trifluoromethyl-1,3-thiazole-5-carboxylate) (S13 -3), which is known as millet safener for millet against damage of alachlor and metolachlor, "CL 304415" (CAS No. 31541-57-8) (4-carboxy-3,4-dihydro-2H-1 benzopyran-4-acetic acid) (S13-4) from American Cyanamid, which is known as a safener for corn against damage of imidazolinones, "MG 191" (CAS Reg. No. 96420-72-3) (2-dichloromethyl- 2-methyl-1,3-dioxolane) (S13-5) from Nitrokemia, which is known as safener for corn, "MG-838" (CAS Reg. No. 133993-74-5) (2-propenyl 1 -oxa-4-azaspiro [4.5] decane-4-carbodithioate) (S13-6) from Nitrokemia, "Disulfoton" (0,0-di ethyl S-2-ethylthioethyl phosphorodithioate) (S13-7), "dietholate" (0,0-diethyl-O-phenylphosphorothioate) (S13-8), "mephenate" (4-chlorophenyl-methylcarbamate) (S13-9).
514) Wirkstoffe, die neben einer herbiziden Wirkung gegen Schadpflanzen auch Safenerwirkung an Kulturpflanzen wie Reis aufweisen, wie z. B. 514) active substances which, in addition to a herbicidal activity against harmful plants, also have safener action on crops such as rice, such as, for example, rice. B.
"Dimepiperate" oder "MY-93" (S-1 -Methyl-1 -phenylethyl-piperidin-1 -carbothioat), das als Safener für Reis gegen Schäden des Herbizids Molinate bekannt ist, "Daimuron" oder "SK 23" (1 -(1 -Methyl-1 -phenylethyl)-3-p-tolyl-harnstoff), das als Safener für Reis gegen Schäden des Herbizids Imazosulfuron bekannt ist, "Cumyluron" = "JC-940" (3- (2-Chlorphenylmethyl)-1 -(1 -methyl-1 -phenyl-ethyl)harnstoff, siehe JP-A-60087254), das als Safener für Reis gegen Schäden einiger Herbizide bekannt ist, "Dimepiperate" or "MY-93" (S-1-methyl-1-phenylethyl-piperidine-1-carbothioate), which is known as a safener for rice against damage by the herbicide Molinate, "daimuron" or "SK 23" (1 - (1-methyl-1-phenylethyl) -3-p-tolyl-urea) known as safener for rice against damage of the herbicide imazosulfuron, "cumyluron" = "JC-940" (3- (2-chlorophenylmethyl) 1 - (1-methyl-1-phenylethyl) urea, see JP-A-60087254), which is known as a safener for rice against damage of some herbicides,
"Methoxyphenon" oder "NK 049" (3,3'-Dimethyl-4-methoxy-benzophenon), das als Safener für Reis gegen Schäden einiger Herbizide bekannt ist, "CSB" (1 -Brom-4-"Methoxyphenone" or "NK 049" (3,3'-dimethyl-4-methoxy-benzophenone), which is known as a safener for rice against damage of some herbicides, "CSB" (1-Bromo-4-)
(chlormethylsulfonyl)benzol) von Kumiai, (CAS-Reg.Nr. 54091 -06-4), das als Safener gegen Schäden einiger Herbizide in Reis bekannt ist. (chloromethylsulfonyl) benzene) from Kumiai, (CAS No. 54091-06-4), which is known as a safener against damage of some herbicides in rice.
515) Verbindungen der Formel (S15) oder deren Tautomere wie sie in der WO-A-2008/131861 und WO-A-2008/131860 beschrieben sind 515) compounds of formula (S15) or their tautomers as described in WO-A-2008/131861 and WO-A-2008/131860
worin  wherein
RH1 einen (d-CeJHaloalkylrest bedeutet und RH 1 represents a (d-CeHHaloalkylrest and
RH2 Wasserstoff oder Halogen bedeutet und RH 2 is hydrogen or halogen and
RH3, RH4 unabhängig voneinander Wasserstoff, (Ci-Cir,)Alkyl, (C2-Cir,)Alkenyl oder (C2-Ci6)Alkinyl, wobei jeder der letztgenannten 3 Reste unsubstituiert oder durch einen oder mehrere Reste aus der Gruppe Halogen, Hydroxy, Cyano, (Ci-C4)Alkoxy, (CrC4)Haloalkoxy, (Ci-C4)Alkylthio, (Ci-C4)Alkylamino, Di[(d-C4)alkyl]-amino, RH 3, RH 4 independently represent hydrogen, (Ci-Cir,) alkyl, (C2-Cir,) alkenyl or (C2-Ci6) alkynyl, where each of the 3 last-mentioned radicals being unsubstituted or substituted by one or more radicals from the group halogen hydroxy, cyano, (Ci-C 4) alkoxy, (CrC 4) haloalkoxy, (Ci-C 4) alkylthio, (Ci-C 4) alkylamino, di [(dC 4) alkyl] amino,
[(Ci-C4)Alkoxy]-carbonyl, [(Ci-C4)Haloalkoxy]-carbonyl, (C3-C6)Cycloalkyl, das unsubstituiert oder substituiert ist, Phenyl, das unsubstituiert oder substituiert ist, und Heterocyclyl, das unsubstituiert oder substituiert ist, substituiert ist, oder (C3- Ce)Cycloalkyl, (C4-C6)Cycloalkenyl, (Ca-CeJCycloalkyl, das an einer Seite des Rings mit einem 4 bis 6-gliedrigen gesättigten oder ungesättigten carbocyclischen Ring kondensiert ist, oder (C4-C6)Cycloalkenyl, das an einer Seite des Rings mit einem 4 bis 6-gliedrigen gesättigten oder ungesättigten carbocyclischen Ring kondensiert ist, wobei jeder der letztgenannten 4 Reste unsubstituiert oder durch einen oder mehrere Reste aus der Gruppe Halogen, Hydroxy, Cyano, (C1 -C4)Alkyl, (C1 -C4)Haloalkyl, (C1 -C4)Alkoxy, (C1 -C4)Haloalkoxy, (C1 -C4)Alkylthio, (C1 -C4)Alkylamino, Di[(C1 - C4)alkyl]-amino, [(C1 -C4)Alkoxy]-carbonyl, [(C1 -C4)Haloalkoxy]-carbonyl, [(C 1 -C 4 ) alkoxy] carbonyl, [(C 1 -C 4 ) haloalkoxy] carbonyl, (C 3 -C 6 ) cycloalkyl which is unsubstituted or substituted, phenyl which is unsubstituted or substituted, and heterocyclyl, which is unsubstituted or substituted, is substituted, or (C3- Ce) cycloalkyl, (C 4 -C 6) cycloalkenyl, (Ca-CeJCycloalkyl condensed on one side of the ring with a 4 to 6-membered saturated or unsaturated carbocyclic ring , or (C 4 -C 6) cycloalkenyl fused on one side of the ring with a 4- to 6-membered saturated or unsaturated carbocyclic ring, each of the last 4 radicals unsubstituted or substituted by one or more of halo, hydroxy , Cyano, (C1-C4) alkyl, (C1-C4) haloalkyl, (C1-C4) alkoxy, (C1-C4) haloalkoxy, (C1-C4) alkylthio, (C1-C4) alkylamino, di [(C1- C4) alkyl] amino, [(C1-C4) alkoxy] carbonyl, [(C1-C4) haloalkoxy] carbonyl,
(C3-C6)Cycloalkyl, das unsubstituiert oder substituiert ist, Phenyl, das unsubstituiert oder substituiert ist, und Heterocyclyl, das unsubstituiert oder substituiert ist, substituiert ist, bedeutet oder  (C 3 -C 6) cycloalkyl which is unsubstituted or substituted, phenyl which is unsubstituted or substituted, and heterocyclyl which is unsubstituted or substituted, or denotes
RH3 (Ci-C4)-Alkoxy, (C2-C4)Alkenyloxy, (C2-C6)Alkinyloxy oder (C2-C4)Haloalkoxy bedeutet und RH 3 is (C 1 -C 4 ) alkoxy, (C 2 -C 4 ) alkenyloxy, (C 2 -C 6 ) alkynyloxy or (C 2 -C 4 ) haloalkoxy and
RH4 Wasserstoff oder (Ci-C4)-Alkyl bedeutet oder RH3 und RH4 zusammen mit dem direkt gebundenen N-Atom einen vier- bis RH 4 is hydrogen or (C 1 -C 4 ) -alkyl or RH 3 and RH 4 together with the directly attached N atom have a four-to-one
achtgliedrigen eight-membered
heterocyclischen Ring, der neben dem N-Atom auch weitere Heteroringatome, vorzugsweise bis zu zwei weitere Heteroringatome aus der Gruppe N, O und S enthalten kann und der unsubstituiert oder durch einen oder mehrere Reste aus der Gruppe Halogen, Cyano, Nitro. (CrC4)Alkyl, (Ci-C4)Haloalkyl, (Ci-C4)Alkoxy, (Ci- C4)Haloalkoxy und (d-C4)Alkylthio substituiert ist, bedeutet. heterocyclic ring which in addition to the N-atom may also contain other hetero ring atoms, preferably up to two further hetero ring atoms from the group N, O and S and unsubstituted or by one or more radicals from the group halogen, cyano, nitro. (CrC 4) alkyl, (Ci-C 4) haloalkyl, (Ci-C 4) alkoxy, (Ci C 4) haloalkoxy and (dC 4) alkylthio means.
S16) Wirkstoffe, die vorrangig als Herbizide eingesetzt werden, jedoch auch S16) active substances, which are primarily used as herbicides, but also
Safenerwirkung auf Kulturpflanzen aufweisen, z.B. (2,4-Dichlorphenoxy)essigsäure (2,4-D), (4-Chlorphenoxy)essigsäure, (R,S)-2-(4-Chlor-o-tolyloxy)propionsäure Safeners on crops, e.g. (2,4-dichlorophenoxy) acetic acid (2,4-D), (4-chlorophenoxy) acetic acid, (R, S) -2- (4-chloro-o-tolyloxy) propionic acid
(Mecoprop), 4-(2,4-Dichlorphenoxy)buttersäure (2,4-DB), (4-Chlor-o-tolyloxy)- essigsäure (MCPA), 4-(4-Chlor-o-tolyloxy)buttersäure, 4-(4-Chlorphenoxy)- buttersäure, 3.6-Dichlor-2-methoxybenzoesäure (Dicamba), 1 -(Ethoxycarbonyl)ethyl- 3,6-dichlor-2-methoxybenzoat (Lactidichlor-ethyl). (Mecoprop), 4- (2,4-dichlorophenoxy) butyric acid (2,4-DB), (4-chloro-o-tolyloxy) acetic acid (MCPA), 4- (4-chloro-o-tolyloxy) butyric acid, 4- (4-chlorophenoxy) butyric acid, 3.6-dichloro-2-methoxybenzoic acid (Dicamba), 1- (ethoxycarbonyl) ethyl-3,6-dichloro-2-methoxybenzoate (lactidichloroethyl).
Pflanzenreife beeinflussende Stoffe: Plant-maturing substances:
Als Kombinationspartner für die Verbindungen der allgemeinen Formel (I) in As a combination partner for the compounds of general formula (I) in
Mischungsformulierungen oder im Tank-Mix sind beispielsweise bekannte Wirkstoffe, die auf einer Inhibition von beispielsweise 1 -Aminocyclopropan-1 -carboxylatsynthase, 1 -aminocyclopropane-1 -carboxylatoxidase und den Ethylenrezeptoren, z. B. ETR1 , ETR2, ERS1 , ERS2 oder EIN4, beruhen, einsetzbar, wie sie z. B. in Biotechn. Adv. 2006, 24, 357-367; Bot. Bull. Acad. Sin. 199, 40, 1 -7 oder Plant Growth Reg. 1993, 1 3, 41 -46 und dort zitierter Literatur beschrieben sind. Mixture formulations or in the tank mix are, for example, known active compounds which are based on an inhibition of, for example, 1-aminocyclopropane-1-carboxylate synthase, 1-aminocyclopropane-1-carboxylate oxidase and the ethylene receptors, eg. As ETR1, ETR2, ERS1, ERS2 or EIN4, are based, can be used as z. B. in biotechnology. Adv. 2006, 24, 357-367; Bot. Bull. Acad. Sin. 199, 40, 1-7 or Plant Growth Reg. 1993, 13, 41-46 and literature cited therein.
Als bekannte die Pflanzenreife beeinflussende Stoffe, die mit den Verbindungen der allgemeinen Formel (I) kombiniert werden können, sind z.B. folgende Wirkstoffe zu nennen (die Verbindungen sind entweder mit dem "common name" nach der As known plant ripening affecting substances which can be combined with the compounds of the general formula (I) are e.g. to name the following active ingredients (the compounds are either with the "common name" after the
International Organization for Standardization (ISO) oder mit dem chemischen Namen oder mit der Codenummer bezeichnet) und umfassen stets sämtliche International Organization for Standardization (ISO) or with the chemical name or code number) and always include all
Anwendungsformen wie Säuren, Salze, Ester und Isomere wie Stereoisomere und optische Isomere. Dabei sind beispielhaft eine und zum Teil auch mehrere Use forms such as acids, salts, esters and isomers such as stereoisomers and optical isomers. Here are one example and some also several
Anwendungsformen genannt: Rhizobitoxin, 2-Amino-ethoxy-vinylglycin (AVG), Methoxyvinylglycin (MVG), Application forms called: Rhizobitoxin, 2-amino-ethoxy-vinylglycine (AVG), methoxyvinylglycine (MVG),
Vinylglycin, Aminooxyessigsäure, Sinefungin, S-Adenosylhomocystein, 2-Keto-4- Methylthiobutyrat, (lsopropyliden)-aminooxyessigsäure-2-(methoxy)-2-oxoethylester, (lsopropyliden)-aminooxyessigsäure-2-(hexyloxy)-2-oxoethylester, (Cyclohexylidene)- aminooxyessigsäure-2-(isopropyloxy)-2-oxoethylester, Putrescin, Spermidin, Spermin, 1 ,8-Diamino-4-aminoethyloctan, L-Canalin, Daminozid, 1 -Aminocyclopropyl-1 - carbonsäure-methylester, N- ethyl-1 -aminocyclopropyl-1 -carbonsäure, 1- Aminocyclopropyl-1 -carbonsäureamid, Substituierte 1 -Aminocyclopropyl-1 - carbonsäurederivate wie sie in DE3335514, EP30287, DE2906507 oder US5123951 beschrieben werden, 1 -Aminocyclopropyl-1 -hydroxamsäure, 1 -Methylcyclopropen, 3- Methylcyclopropen, 1 -Ethylcyclopropen, 1 -n-Propylcyclopropen, 1-Cyclopropenyl- Methanol, Carvon, Eugenol, Natriumcycloprop-1 -en-1 -ylacetat, Natriumcycloprop-2-en- 1 -ylacetat, Natrium-3-(cycloprop-2-en-1 -yl)propanoat, Natrium-3-(cycloprop-1-en-1- yl)propanoat, Jasmonsäure, Jasmonsäuremethylester, Jasmonsäureethylester. Vinyl glycine, aminooxyacetic acid, sinefungin, S-adenosyl homocysteine, 2-keto-4-methylthiobutyrate, (isopropylidene) aminooxyacetic acid 2- (methoxy) -2-oxoethyl ester, (isopropylidene) aminooxyacetic acid 2- (hexyloxy) -2-oxoethyl ester, (Cyclohexylidenes) - aminooxyacetic acid 2- (isopropyloxy) -2-oxoethyl ester, putrescine, spermidine, spermine, 1, 8-diamino-4-aminoethyloctane, L-canaline, daminozide, 1-aminocyclopropyl-1-carboxylic acid methyl ester, N- ethyl-1-aminocyclopropyl-1-carboxylic acid, 1-aminocyclopropyl-1-carboxamide, substituted 1-aminocyclopropyl-1-carboxylic acid derivatives as described in DE3335514, EP30287, DE2906507 or US5123951, 1-aminocyclopropyl-1-hydroxamic acid, 1-methylcyclopropene , 3-methylcyclopropene, 1-ethylcyclopropene, 1 -n-propylcyclopropene, 1-cyclopropenylmethanol, carvone, eugenol, sodium cycloprop-1 -en-1-ylacetate, sodium cycloprop-2-ene-1-ylacetate, sodium 3- ( cycloprop-2-en-1-yl) propanoate, sodium 3- (cycloprop-1-en-1-yl) propanoate, jasmonic acid e, Jasmonsäuremethylester, Jasmonsäureethylester.
Pflanzengesundheit und Keimung beeinflussende Stoffe: Plant health and germination affecting substances:
Als Kombinationspartner für die Verbindungen der allgemeinen Formel (I) in As a combination partner for the compounds of general formula (I) in
Mischungsformulierungen oder im Tank-Mix sind beispielsweise bekannte Wirkstoffe, die die Pflanzengesundheit beeinflussen, einsetzbar (die Verbindungen sind entweder mit dem "common name" nach der International Organization for Standardization (ISO) oder mit dem chemischen Namen oder mit der Codenummer bezeichnet und umfassen stets sämtliche Anwendungsformen wie Säuren, Salze, Ester und Isomere wie Stereoisomere und optische Isomere): Sarcosin, Phenylalanin, Tryptophan, N'-Mixture formulations or in the tank mix, for example, known active ingredients that affect plant health, can be used (the compounds are either with the "common name" according to the International Organization for Standardization (ISO) or with the chemical name or with the code number designated and always include all forms of use, such as acids, salts, esters and isomers, such as stereoisomers and optical isomers): sarcosine, phenylalanine, tryptophan, N '
Methyl-1-phenyl-1 -N,N-diethylaminomethanesulfonamid, Apio-galacturonane wie sie in WO2010017956 beschrieben werden, 4-Oxo-4-[(2-phenylethyl)amino]butansäure, 4- {[2-(1 H-lndol-3-yl)ethyl]amino}-4-oxobutansäure, 4-[(3-Methylpyridin-2-yl)amino]-4- oxobutansäure, Allantoin, 5-Aminolevulinsäure, (2S,3R)-2-(3.4-Dihydroxyphenyl)-3,4- dihydro-2H-chromen-3,5.7-triol und strukturell verwandte Catechine wie sie in Methyl-1-phenyl-1-N, N-diethylaminomethanesulfonamide, apio-galacturonans as described in WO2010017956, 4-oxo-4 - [(2-phenylethyl) amino] butanoic acid, 4- {[2- (1H- indol-3-yl) ethyl] amino} -4-oxobutanoic acid, 4 - [(3-methylpyridin-2-yl) amino] -4-oxobutanoic acid, allantoin, 5-aminolevulinic acid, (2S, 3R) -2- (3.4 -Dihydroxyphenyl) -3,4-dihydro-2H-chromen-3,5,7-triol; and structurally related catechins as described in U.S. Pat
WO2010122956 beschrieben werden, 2-Hydroxy-4-(methylsulfanyl)butansäure, (3E,3aR,8ßS)-3-({[(2R)-4-Methyl-5-oxo-2.5-dihydrofuran-2-yl]oxy}methylen)-3,3a,4,8ß- tetrahydro-2H-indeno[1 ,2-b]furan-2-on und analoge Lactone wie sie in EP2248421 beschrieben werden, Abscisinsäure, (2Z.4E)-5-[6-Ethinyl-1 -hydroxy-2,6-dimethyl-4- oxocyclohex-2-en-1 -yl]-3-methylpenta-2,4-diensäure, Methyl-(2Z,4E)-5-[6-ethinyl-1- hydroxy-2.6-dimethyl-4-oxocyclohex-2-en-1 -yl]-3-methylpenta-2.4-dienoat, 4- Phenylbuttersäure, Natrium-4-phenylbutanoat, Kalium-4-phenylbutanoat. Herbizide oder Pflanzenwachstumsregulatoren: WO2010122956, 2-hydroxy-4- (methylsulfanyl) butanoic acid, (3E, 3aR, 8βS) -3 - ({[(2R) -4-methyl-5-oxo-2,5-dihydrofuran-2-yl] oxy} methylene) -3,3a, 4,8β-tetrahydro-2H-indeno [1,2-b] furan-2-one and analogous lactones as described in EP2248421, abscisic acid, (2Z.4E) -5- [6 Ethynyl-1-hydroxy-2,6-dimethyl-4- oxocyclohex-2-en-1-yl] -3-methylpenta-2,4-dienoic acid, methyl (2Z, 4E) -5- [6-ethynyl-1-hydroxy-2,6-dimethyl-4-oxocyclohex-2- en -1 -yl] -3-methylpenta-2,4-dienoate, 4-phenylbutyric acid, sodium 4-phenylbutanoate, potassium 4-phenylbutanoate. Herbicides or plant growth regulators:
Als Kombinationspartner für die Verbindungen der allgemeinen Formel (I) in As a combination partner for the compounds of general formula (I) in
Mischungsformulierungen oder im Tank-Mix sind beispielsweise bekannte Wirkstoffe, die auf einer Inhibition von beispielsweise Acetolactat-Synthase, Acetyl-CoA- Carboxylase, Cellulose-Synthase, Enolpyruvylshikimat-3-phosphat-Synthase, Mixture formulations or in the tank mix are, for example, known active substances which are based on an inhibition of, for example, acetolactate synthase, acetyl-CoA carboxylase, cellulose synthase, enolpyruvylshikimate-3-phosphate synthase,
Glutamin-Synthetase, p-Hydroxyphenylpyruvat-Dioxygenase, Phytoendesaturase, Photosystem I, Photosystem II, Protoporphyrinogen-Oxidase beruhen, einsetzbar, wie sie z.B. aus Weed Research 26 (1986) 441 -445 oder "The Pesticide Manual", 14th edition, The British Crop Protection Council and the Royal Soc. of Chemistry, 2006 sowie der entsprechenden 15ten Ausgabe und dort zitierter Literatur beschrieben sind.  Glutamine synthetase, p-hydroxyphenylpyruvate dioxygenase, phytoene desaturase, photosystem I, photosystem II, protoporphyrinogen oxidase, can be used, e.g. from Weed Research 26 (1986) 441-445 or "The Pesticide Manual", 14th edition, The British Crop Protection Council and the Royal Soc. of Chemistry, 2006 and the corresponding 15th edition and literature cited therein.
Als bekannte Herbizide oder Pflanzenwachstumsregulatoren, die mit Verbindungen der allgemeinen Formel (I) kombiniert werden können, sind z.B. folgende Wirkstoffe zu nennen (die Verbindungen sind entweder mit dem "common name" nach der As known herbicides or plant growth regulators which can be combined with compounds of general formula (I), e.g. to name the following active ingredients (the compounds are either with the "common name" after the
International Organization for Standardization (ISO) oder mit dem chemischen Namen oder mit der Codenummer bezeichnet) und umfassen stets sämtliche International Organization for Standardization (ISO) or with the chemical name or code number) and always include all
Anwendungsformen wie Säuren, Salze, Ester und Isomere wie Stereoisomere und optische Isomere. Dabei sind beispielhaft eine und zum Teil auch mehrere Use forms such as acids, salts, esters and isomers such as stereoisomers and optical isomers. Here are one example and some also several
Anwendungsformen genannt: Application forms called:
Acetochlor, Acibenzolar, Acibenzolar-S-methyl, Acifluorfen, Acifiuorfen-sodium, Aclonifen, Alachlor, Allidochlor, Alloxydim, Alloxydim-sodium, Ametryn, Amicarbazone, Amidochlor, Amidosulfuron, Aminocyclopyrachlor, Aminopyralid, Amitrole, Acetochlor, acibenzolar, acibenzolar-S-methyl, acifluorfen, acified-sodium, aclonifen, alachlor, allidochlor, alloxydim, alloxydim-sodium, ametryn, amicarbazone, amidochlor, amidosulfuron, aminocyclopyrachlor, aminopyralid, amitrole,
Ammoniumsulfamat, Ancymidol, Anilofos, Asulam, Atrazine, Azafenidin, Azimsulfuron, Aziprotryn, Beflubutamid, Benazolin, Benazolin-ethyl, Bencarbazone, Benfluralin,Ammonium sulfamate, ancymidol, anilofos, asulam, atrazines, azafenidine, azimsulfuron, aziprotryn, beflubutamide, benazoline, benazolin-ethyl, bencarbazone, benfluralin,
Benfuresate, Bensulide, Bensulfuron, Bensulfuron-methyl, Bentazone, Benzfendizone, Benzobicyclon, Benzofenap, Benzofluor, Benzoylprop, Bicyclopyrone, Bifenox, Bilanafos, Bilanafos-natrium, Bispyribac, Bispyribac-natrium, Bromacil, Bromobutide, Bromofenoxim, Bromoxynil, Bromuron, Buminafos, Busoxinone, Butachlor, Butafenacil, Butamifos, Butenachlor, Butralin, Butroxydim, Butylate, Cafenstrole, Carbetamide, Carfentrazone, Carfentrazone-ethyl, Chlomethoxyfen, Chloramben, Chlorazifop, Chlorazifop-butyl, Chlorbromuron, Chlorbufam, Chlorfenac, Chlorfenac- natrium, Chlorfenprop, Chlorflurenol, Chlorflurenol-methyl, Chloridazon, Chlorimuron, Chlorimuron-ethyl, Chlormequat-chlorid, Chlornitrofen, Chlorophthalim, Chlorthal- dimethyl, Chlorotoluron, Chlorsulfuron, Cinidon, Cinidon-ethyl, Cinmethylin, Benfuresate, Bensulide, Bensulfuron, Bensulfuron-methyl, Bentazone, Benzofendizone, Benzobicyclone, Benzofenap, Benzofluor, Benzoylprop, Bicyclopyrone, Bifenox, Bilanafos, Bilanafos sodium, Bispyribac, Bispyribac sodium, Bromacil, Bromobutide, Bromofenoxime, Bromoxynil, Bromuron, Buminafos, Busoxinone, Butachlor, Butafenacil, butamifos, butenachlor, butraline, butroxydim, butylates, cafenstroles, carbetamides, carfentrazone, carfentrazone-ethyl, chlomethoxyfen, chloramben, chloroazifop, chlorazifop-butyl, chlorobromuron, chlorobufam, chlorfenac, chlorfenacsodium, chlorfenprop, chlorflurenol, chlorflurenol-methyl, Chloridazon, chlorimuron, chlorimuron-ethyl, chlormequat chloride, chloronitrofen, chlorophthalim, chlorothal-dimethyl, chlorotoluron, chlorosulfuron, cinidone, cinidon-ethyl, cinmethylin,
Cinosulfuron, Clethodim, Clodinafop, Clodinafop-propargyl, Clofencet, Clomazone, Clomeprop, Cloprop, Clopyralid, Cloransulam, Cloransulam-methyl, Cumyluron, Cyanamide, Cyanazine, Cyclanilide, Cycloate, Cyclosulfamuron, Cycloxydim, Cinosulfuron, clethodim, clodinafop, clodinafop-propargyl, clofencet, clomazone, clomeprop, cloprop, clopyralid, cloransulam, cloransulam-methyl, cumyluron, cyanamide, cyanazine, cyclanilide, cycloate, cyclosulfamuron, cycloxydim,
Cycluron, Cyhalofop, Cyhalofop-butyl, Cyperquat, Cyprazine, Cyprazole, 2,4-D, 2,4- DB, Daimuron/Dymron, Dalapon, Daminozid, Dazomet, n-Decanol, Desmedipham, Desmetryn, Detosyl-Pyrazolate (DTP), Diallate, Dicamba, Dichlobenil, Dichlorprop, Dichlorprop-P, Diclofop, Diclofop-methyl, Diclofop-P-methyl, Diclosulam, Diethatyl, Diethatyl-ethyl, Difenoxuron, Difenzoquat, Diflufenican, Diflufenzopyr, Diflufenzopyr- natrium, Dimefuron, Dikegulac-sodium, Dimefuron, Dimepiperate, Dimethachlor, Dirne thametryn, Dimethenamid, Dimethenamid-P, Dimethipin, Dimetrasulfuron, Dinitramine, Dinoseb, Dinoterb, Diphenamid, Dipropetryn, Diquat, Diquat-dibromide, Dithiopyr, Diuron, DNOC, Eglinazine-ethyl, Endothal, EPTC, Esprocarb, Ethalfluralin, Ethametsulfuron, Ethametsulfuron-methyl, Ethephon, Ethidimuron, Ethiozin, Cycluron, Cyhalofop, Cyhalofop-butyl, Cyperquat, Cyprazine, Cyprazole, 2,4-D, 2,4-DB, Daimurone / Dymron, Dalapon, Daminozide, Dazomet, n-decanol, Desmedipham, Desmetryn, Detosyl-Pyrazolate (DTP) , Dialkylates, dicamba, dichlobenil, dichlorprop, dichlorprop-P, diclofop, diclofop-methyl, diclofop-P-methyl, diclosulam, diethatyl, diethyl-ethyl, difenoxuron, difenzoquat, diflufenican, difluufenzopyr, difluoropentyrimidate, dimefuron, dikegulac-sodium , Dimefuron, dimepiperate, dimethachlor, thymotrine, dimethenamid, dimethenamid-P, dimethipine, dimetrasulfuron, dinitramine, dinoseb, dinoterb, diphenetramine, dipropetryn, diquat, diquat-dibromide, dithiopyr, diuron, DNOC, eglinazine-ethyl, endothal, EPTC, Esprocarb, ethalfluralin, ethametsulfuron, ethametsulfuron-methyl, ethephon, ethidimuron, ethiozine,
Ethofumesate, Ethoxyfen, Ethoxyfen-ethyl, Ethoxysuifuron, Etobenzanid, F-5331 , d.h. N-[2-Chlor-4-fluor-5-[4-(3-fluorpropyl)-4.5-dihydro-5-oxo-1 H-tetrazol-1-yl]-phenyl]- ethansulfonamid, F-7967, d. h. 3-[7-Chlor-5-fluor-2-(trifluormethyl)-1 H-benzimidazol-4- yl]-1 -methyl-6-(trifluormethyl)pyrimidin-2,4(1 H,3H)-dion, Fenoprop, Fenoxaprop, Fenoxaprop-P, Fenoxaprop-ethyl, Fenoxaprop-P-ethyl, Fenoxasulfone, Fentrazamide, Fenuron, Flamprop, Flampro p-M-isopropyl, Flamprop-M-methyl, Flazasulfuron, Florasulam, Fluazifop, Fluazifop-P, Fluazifop-butyl, Fluazifop-P-butyl, Fluazolate, Flucarbazone, Flucarbazone-sodium, Flucetosulfuron, Fluchloralin, Flufenacet (Thiafluamide), Flufenpyr, Flufenpyr-ethyl, Flumetralin, Flumetsulam, Flumiclorac, Flumiclorac-pentyl, Flumioxazin, Flumipropyn, Fluometuron, Fluorodifen, Ethofumesate, ethoxyfen, ethoxyfen-ethyl, ethoxy-suifuron, etobenzanide, F-5331, i. N- [2-Chloro-4-fluoro-5- [4- (3-fluoro-propyl) -4,5-dihydro-5-oxo-1H-tetrazol-1-yl] -phenyl] -ethanesulfonamide, F-7967, d , H. 3- [7-chloro-5-fluoro-2- (trifluoromethyl) -1H-benzimidazol-4-yl] -1-methyl-6- (trifluoromethyl) pyrimidine-2,4 (1H, 3H) -dione, Fenoprop, fenoxaprop, fenoxaprop-P, fenoxaprop-ethyl, fenoxaprop-P-ethyl, fenoxasulfones, fentrazamides, fenuron, flamprop, flampro pM-isopropyl, flamprop-M-methyl, flazasulfuron, florasulam, fluazifop, fluazifop-P, fluazifop-butyl , Fluazifop-P-butyl, Fluazolate, Flucarbazone, Flucarbazone-sodium, Flucetosulfuron, Fluchloralin, Flufenacet (Thiafluamide), Flufenpyr, Flufenpyr-ethyl, Flumetralin, Flumetsulam, Flumiclorac, Flumiclorac-pentyl, Flumioxazin, Flumipropyn, Fluometuron, Fluorodifen,
Fluoroglycofen, Fluoroglycofen-ethyl, Flupoxam, Flupropacil, Flupropanate, Fluoroglycofen, fluoroglycofen-ethyl, flupoxam, flupropacil, flupropanate,
Flupyrsulfuron, Flupyrsulfuron-methyl-sodium, Flurenol, Flurenol-butyl, Fluridone, Flurochloridone, Fluroxypyr, Fluroxypyr-meptyl, Flurprimidol, Flurtamone, Fluthiacet, Fluthiacet-methyl, Fluthiamide, Fomesafen, Foramsulfuron, Forchlorfenuron,  Flupyrsulfuron, Flupyrsulfuron-methyl-sodium, Flurenol, Flurenol-butyl, Fluridone, Flurochloridone, Fluroxypyr, Fluroxypyr-meptyl, Flurprimidol, Flurtamone, Fluthiacet, Fluthiacet-methyl, Fluthiamide, Fomesafen, Foramsulfuron, Forchlorfenuron,
Fosamine, Furyloxyfen, Gibberellinsäure, Glufosinate, Glufosinate-ammonium, Glufosinate-P, Glufosinate-P-ammonium, Glufosinate-P-natrium, Glyphosate, Fosamines, furyloxyfen, gibberellic acid, glufosinate, glufosinate-ammonium, Glufosinate-P, glufosinate-P-ammonium, glufosinate-P-sodium, glyphosate,
Glyphosate-isopropyiammonium, H-9201 , d. h. 0-(2.4-Dimethyl-6-nitrophenyl)-0-ethyl- isopropylphosphoramidothioat, Halosafen, Halosulfuron, Halosulfuron-methyl, Glyphosate isopropylammonium, H-9201, d. H. 0- (2,4-dimethyl-6-nitrophenyl) -0-ethyl-isopropylphosphoramidothioate, halosafen, halosulfuron, halosulfuron-methyl,
Haloxyfop, Haloxyfop-P, Haloxyfop-ethoxyethyl, Haloxyfop-P-ethoxyethyl, Haloxyfop- methyl, Haloxyfop-P-methyl, Hexazinone, HW-02, d. h. 1 -(Dimethoxyphosphoryl)- ethyl(2,4-dichlorphenoxy)acetat, Imazamethabenz, Imazamethabenz-methyl, Haloxyfop, Haloxyfop-P, Haloxyfopethoxyethyl, Haloxyfop-P-ethoxyethyl, Haloxyfop- methyl, Haloxyfop-P-methyl, Hexazinone, HW-02, d. H. 1- (dimethoxyphosphoryl) ethyl (2,4-dichlorophenoxy) acetate, imazamethabenz, imazamethabenz-methyl,
Imazamox, Imazamox-ammonium, Imazapic, Imazapyr, Imazapyr- isopropylammonium, Imazaquin, Imazaquin-ammonium, Imazethapyr, Imazethapyr- ammonium, Imazosulfuron, Inabenfide, Indanofan, Indaziflam, Indolessigsäure (IAA), 4-lndol-3-ylbuttersäure (IBA), lodosulfuron, lodosulfuron-methyl-natrium, loxynil, Ipfencarbazone, Isocarbamid, Isopropalin, Isoproturon, Isouron, Isoxaben, Imazamox, imazamox-ammonium, imazapic, imazapyr, imazapyrisopropylammonium, imazaquin, imazaquin-ammonium, imazethapyr, imazethapyrammonium, imazosulfuron, inabenfide, indanofan, indaziflam, indoleacetic acid (IAA), 4-indol-3-yl-butyric acid (IBA), iodosulfuron, iodosulfuron-methyl-sodium, loxynil, isoparbazone, isocarbamide, isopropalin, isoproturon, isourone, isoxaben,
Isoxachlortole, Isoxaflutole, Isoxapyrifop, KUH-043, d. h. 3-({[5-(Difluormethyl)-1 - methyl-3-(trifluormeihyl)-1 H-pyrazol-4-yl]methyl}sulfonyl)-5,5-dimethyl-4,5-dihydro-1 .2- oxazol, Karbutilate, Ketospiradox, Lactofen, Lenacil, Linuron, Maleinsäurehydrazid, MCPA, MCPB, MCPB-methyl, -ethyl und -natrium, Mecoprop, Mecoprop-natrium,Isoxachlortole, Isoxaflutole, Isoxapyrifop, KUH-043, d. H. 3 - ({[5- (Difluoromethyl) -1-methyl-3- (trifluoromethyl) -1H-pyrazol-4-yl] methyl} sulfonyl) -5,5-dimethyl-4,5-dihydro-1: 2 oxazole, carbutilates, ketospiradox, lactofen, lenacil, linuron, maleic hydrazide, MCPA, MCPB, MCPB-methyl, -ethyl and -sodium, mecoprop, mecoprop-sodium,
Mecoprop-butotyi, Mecoprop-P-butotyl, Mecoprop-P-dimethylammonium, Mecoprop-P- 2-ethylhexyl, Mecoprop-P-kalium, Mefenacet, Mefluidide, Mepiquat-chlorid, Mecopropbututyl, mecoprop-p-butotyl, mecoprop-P-dimethylammonium, mecoprop-P-2-ethylhexyl, mecoprop-P-potassium, mefenacet, mefluidides, mepiquat chloride,
Mesosulfuron, Mesosulfuron-methyl, Mesotrione, Methabenzthiazuron, Metam, Metamifop, Metamitron, Metazachlor, Metazasulfuron, Methazole, Methiopyrsulfuron, Methiozolin, Methoxyphenone, Methyldymron, 1 -Methylcyclopropen, Mesosulfuron, mesosulfuron-methyl, mesotrione, methabenzthiazuron, metam, metamifop, metamitron, metazachlor, metazasulfuron, methazoles, methiopyrsulfuron, methiozoline, methoxyphenones, methyldymron, 1-methylcyclopropene,
Methylisothiocyanat, Metobenzuron, Metobromuron, Metolachlor, S-Metolachlor, Metosulam, Metoxuron, Metribuzin, Metsulfuron, Metsulfuron-methyl, Molinate, Monalide, Monocarbamide, Monocarbamide-dihydrogensulfat, Monolinuron,  Methyl isothiocyanate, metobenzuron, metobromuron, metolachlor, S-metolachlor, metosulam, metoxuron, metribuzin, metsulfuron, metsulfuron-methyl, molinates, monalides, monocarbamides, monocarbamide dihydrogen sulfate, monolinuron,
Monosulfuron, Monosulfuron-ester, Monuron, MT-128, d. h. 6-Chlor-N-[(2E)-3- chlorprop-2-en-1-yl]-5-methyl-N-phenylpyridazin-3-amin, MT-5950, d. h. N-[3-Chlor-4- (1 -methylethyl)-phenyl]-2-methylpentanamid, NGGC-01 1 , Naproanilide, Napropamide, Naptalam, NC-310, d.h. 4-(2,4-Dichlorobenzoyl)-1 -methyl-5-benzyloxypyrazole, Neburon, Nicosulfuron, Nipyraclofen, Nitralin, Nitrofen, Nitrophenolat-natrium Monosulfuron, Monosulfuron Ester, Monuron, MT-128, d. H. 6-Chloro-N - [(2E) -3-chloroprop-2-en-1-yl] -5-methyl-N-phenylpyridazine-3-amine, MT-5950, d. H. N- [3-chloro-4- (1-methylethyl) phenyl] -2-methylpentanamide, NGGC-01 1, naproanilides, napropamide, naptalam, NC-310, i. 4- (2,4-Dichlorobenzoyl) -1-methyl-5-benzyloxypyrazoles, neburone, nicosulfuron, nipyraclofen, nitrite, nitrofen, nitrophenolate sodium
(Isomerengemisch), Nitrofluorfen, Nonansäure, Norflurazon, Orbencarb, (Mixture of isomers), nitrofluorfen, nonanoic acid, norflurazon, orbencarb,
Orthosulfamuron, Oryzalin, Oxadiargyl, Oxadiazon, Oxasulfuron, Oxaziclomefone, Oxyfluorfen, Paclobutrazol, Paraquat, Paraquat-dichlorid, Pelargonsäure Orthosulfamuron, oryzalin, oxadiargyl, oxadiazon, oxasulfuron, oxaziclomefone, oxyfluorfen, paclobutrazole, paraquat, paraquat-dichloride, pelargonic acid
(Nonansäure), Pendimethalin, Pendralin, Penoxsulam, Pentanochlor, Pentoxazone, Perfluidone, Pethoxamid, Phenisopham, Phenmedipham, Phenmedipham-ethyl, Picloram, Picolinafen, Pinoxaden, Piperophos, Pirifenop, Pirifenop-butyl, Pretilachlor, Primisulfuron, Primisulfuron-methyl, Probenazole, Profluazol, Procyazine, Prodiamine, Prifluraline, Profoxydim, Prohexadione, Prohexadione-calcium, Prohydrojasmone, Prometon, Prometryn, Propachlor, Propanil, Propaquizafop, Propazine, Propham, Propisochlor, Propoxycarbazone, Propoxycarbazone-natrium, Propyrisulfuron, (Nonanoic acid), pendimethalin, pendralin, penoxsulam, pentanochlor, pentoxazone, perfluidone, pethoxamide, phenisopham, phenmedipham, phenmediphamethyl, picloram, picolinafen, pinoxaden, piperophos, pirifenop, pirifenop-butyl, pretilachlor, Primisulfuron, Primisulfuron-methyl, Probenazole, Profluazole, Procyazine, Prodiamine, Prifluralin, Profoxydim, Prohexadione, Prohexadione-calcium, Prohydrojasmone, Prometon, Prometry, Propachlor, Propanil, Propaquizafop, Propazine, Propam, Propisochlor, Propoxycarbazone, Propoxycarbazone-Sodium, Propyrisulfuron,
Propyzamide, Prosulfaiin, Prosulfocarb, Prosulfuron, Prynachlor, Pyraclonil, Pyraflufen, Pyraflufen-ethyl, Pyrasulfotole, Pyrazolynate (Pyrazolate), Pyrazosulfuron, Propyzamide, Prosulfaiin, Prosulfocarb, Prosulfuron, Prynachlor, Pyraclonil, Pyraflufen, Pyraflufen-ethyl, Pyrasulfotole, Pyrazolynate (Pyrazolate), Pyrazosulfuron,
Pyrazosulfuron-ethyl, Pyrazoxyfen, Pyribambenz, Pyribambenz-isopropyl, Pyrazosulfuron-ethyl, pyrazoxyfen, pyribambenz, pyribambenz-isopropyl,
Pyribambenz-propyl, Pyribenzoxim, Pyributicarb, Pyridafol, Pyridate, Pyriftalid, Pyribambenz-propyl, Pyribenzoxime, Pyributicarb, Pyridafol, Pyridate, Pyriftalid,
Pyriminobac, Pyriminobac-methyl, Pyrimisulfan, Pyrithiobac, Pyrithiobac-natrium, Pyroxasulfone, Pyroxsulam, Quinclorac, Quinmerac, Quinoclamine, Quizalofop,Pyriminobac, Pyriminobac-methyl, Pyrimisulfan, Pyrithiobac, Pyrithiobac Sodium, Pyroxasulfones, Pyroxsulam, Quinclorac, Quinmerac, Quinoclamine, Quizalofop,
Quizalofop-ethyl, Quizalofop-P, Quizalofop-P-ethyl, Quizalofop-P-tefuryl, Rimsulfuron, Saflufenacii, Secbumeton, Sethoxydim, Siduron, Simazine, Simetryn, SN-106279, d. h. Methyl-(2R)-2-({7-[2-chlor-4-(trifluormethyl)phenoxy]-2-naphthyl}oxy)-propanoat, Sulcotrione, Sulfallate (CDEC), Sulfentrazone, Sulfometuron, Sulfometuron-methyl, Suifosate (Glyphosate-trimesium), Suifosuifuron, SYN-523, SYP-249, d. h. 1-Ethoxy-3- methyl-1 -oxobut-3-en-2-yl-5-[2-chlor-4-(trifluormethyl)phenoxy]-2-nitrobenzoat, SYP- 300, d. h. 1 -[7-Fluor-3-oxo-4-(prop-2-in-1 -yl)-3,4-dihydro-2H-1 ,4-benzoxazin-6-yl]-3- propyl-2-thioxoimidazolidin-4,5-dion, Tebutam, Tebuthiuron, Tecnazene, Tefuryltrione, Tembotrione, Tepraloxydim, Terbacil, Terbucarb, Terbuchlor, Terbumeton, Quizalofop-ethyl, Quizalofop-P, Quizalofop-P-ethyl, Quizalofop-P-tefuryl, Rimsulfuron, Saflufenacii, Secbumeton, Sethoxydim, Siduron, Simazine, Simetryn, SN-106279, d. H. Methyl (2R) -2 - ({7- [2-chloro-4- (trifluoromethyl) phenoxy] -2-naphthyl} oxy) -propanoate, Sulcotrione, Sulphates (CDEC), Sulfentrazone, Sulfometuron, Sulfometuron-methyl, Suifosate (Glyphosate trimesium), suifosuifuron, SYN-523, SYP-249, d. H. 1-ethoxy-3-methyl-1-oxobut-3-en-2-yl-5- [2-chloro-4- (trifluoromethyl) phenoxy] -2-nitrobenzoate, SYP-300, d. H. 1 - [7-Fluoro-3-oxo-4- (prop-2-yn-1-yl) -3,4-dihydro-2H-1,4-benzoxazin-6-yl] -3-propyl-2- thioxoimidazolidine-4,5-dione, tebutam, tebuthiuron, tecnazene, tefuryltrione, tembotrione, tepraloxydim, terbacil, terbucarb, terbuchlor, terbumeton,
Terbuthylazine, Terbutryn, Thenylchlor, Thiafluamide, Thiazafluron, Thiazopyr,Terbuthylazine, terbutryn, thenylchlor, thiafluamide, thiazafluron, thiazopyr,
Thidiazimin, Thidiazuron, Thiencarbazone, Thiencarbazone-methyl, Thifensulfuron, Thifensulfuron-methyl, Thiobencarb, Thiocarbazil, Topramezone, Tralkoxydim, Thidiazimine, thidiazuron, thiencarbazone, thiencarbazone-methyl, thifensulfuron, thifensulfuron-methyl, thiobencarb, thiocarbazil, topramezone, tralkoxydim,
Triallate, Triasulfuron, Triaziflam, Triazofenamide, Tribenuron, Tribenuron-methyl, Trichloressigsäure (TCA), Triclopyr, Tridiphane, Trietazine, Trifloxysulfuron, Triallate, triasulfuron, triaziflam, triazofenamide, tribenuron, tribenuron-methyl, trichloroacetic acid (TCA), triclopyr, tridiphane, trietazine, trifloxysulfuron,
Trifloxysulfuron-natrium, Trifluralin, Triflusulfuron, Triflusulfuron-methyl, Trimeturon, Trinexapac, Trinexapac-ethyl, Tritosulfuron, Tsitodef, Uniconazole, Uniconazole-P, Vernolate, ZJ-0862, d. h. 3.4-Dichlor-N-{2-[(4,6-dimethoxypyrimidin-2- yl)oxy]benzyl}anilin, sowie die folgenden Verbindungen: Trifloxysulfuron Sodium, Trifluralin, Triflusulfuron, Triflusulfuron-methyl, Trimeturon, Trinexapac, Trinexapac-ethyl, Tritosulfuron, Tsitodef, Uniconazole, Uniconazole-P, Vernolate, ZJ-0862, ie 3,4-dichloro-N- {2 - [(4, 6-dimethoxypyrimidin-2-yl) oxy] benzyl} aniline, and the following compounds:
Die Erfindung soll durch die nachfolgenden biologischen Beispiele veranschaulicht werden, ohne sie jedoch darauf einzuschränken. The invention will be illustrated by the following biological examples without, however, limiting them thereto.
Biologische Beispiele: Biological examples:
Samen von mono- bzw. dikotylen Kulturpflanzen wurden in Holzfasertöpfen in sandigem Lehmboden ausgelegt, mit Erde oder Sand abgedeckt und im Gewächshaus unter guten Wachstumsbedingungen angezogen. Die Behandlung der Seeds of monocotyledonous or dicotyledonous crops were placed in sandy loam soil in wood fiber pots, covered with soil or sand, and grown in the greenhouse under good growth conditions. The treatment of
Versuchspflanzen erfolgte im frühen Laubblattstadium (BBCH10 - BBCH13). Zur Gewährleistung einer uniformen Wasserversorgung vor Stressbeginn wurden die bepflanzten Töpfe vor Substanzapplikation durch Anstaubewässerung mit Wasser versorgt. Die in Form von benetzbaren Pulvern (WP) formulierten erfindungsgemässen Verbindungen wurden als wässrige Suspension mit einer Wasseraufwandmenge von umgerechnet 600 l/ha unter Zusatz von 0.2% Netzmittel (z.B. Ag rotin) auf die grünen Pflanzenteile gesprüht. Unmittelbar nach Substanzapplikation erfolgte die Test plants took place in the early leaves leaf stage (BBCH10 - BBCH13). To ensure a uniform water supply before the onset of stress, the planted pots were supplied with water before being applied with substance by means of dewatering. The novel compounds formulated in the form of wettable powders (WP) were sprayed onto the green parts of plants as an aqueous suspension with a water application rate of 600 l / ha with the addition of 0.2% wetting agent (for example Ag rotin). Immediately after substance administration was the
Stressbehandlung der Pflanzen. Dazu wurden die Töpfe in Plastikeinsätze transferiert, um anschliessendes, zu schnelles Abtrocknen zu verhindern. Der Trockenstress wurde durch langsames Abtrocknen unter folgenden Bedingungen induziert: Stress treatment of the plants. For this purpose, the pots were transferred to plastic inserts in order to prevent subsequent, too rapid drying. The dry stress was induced by slow drying under the following conditions:
„Tag": 14 Stunden beleuchtet bei 26°C "Day": 14 hours lit at 26 ° C
„Nacht": 10 Stunden ohne Beleuchtung bei 18°C. Die Dauer der jeweiligen Stressphasen richtete sich hauptsächlich nach dem Zustand der unbehandelten, gestressten Kontrollpflanzen und variierte somit von Kultur zu Kultur. Sie wurde (durch Wiederbewässerung und. Transfer in ein Gewächshaus mit guten Wachstumsbedingungen) beendet, sobald irreversible Schäden an den unbehandelten, gestressten Kontrollpflanzen zu beobachten waren. Bei dikotylen Kulturen wie beispielsweise Raps und Soja variierte die Dauer der "Night": 10 hours without lighting at 18 ° C. The duration of the respective stress phases was mainly dependent on the condition of the untreated, stressed control plants and thus varied from culture to culture. It was terminated (by irrigation and transfer to a greenhouse with good growth conditions) as soon as irreversible damage to the untreated, stressed control plants was observed. For dicotyledonous crops such as oilseed rape and soybean, the duration of the diet varied
Trockenstressphase zwischen 3 und 6 Tagen, bei monokotylen Kulturen wie beispielweise Weizen, Gerste oder Mais zwischen 6 und 1 1 Tagen. Nach Beendigung der Stressphase folgte eine ca. 5-7 tägige Erholungsphase, während der die Pflanzen abermals unter guten Wachstumsbedingungen im Drought phase between 3 and 6 days, in monocotyledonous crops such as wheat, barley or corn between 6 and 1 1 days. After completion of the stress phase followed by a 5-7 day recovery period during which the plants again under good growth conditions in
Gewächshaus gehalten wurden. Greenhouse were kept.
Um auszuschliessen, dass die beobachteten Effekte von der ggf. fungiziden oder Insektiziden Wirkung der Testverbindungen beeinflusst wurden, wurde zudem darauf geachtet, dass die Versuche ohne Pilzinfektion oder Insektenbefall abliefen. In order to rule out that the observed effects were influenced by the possibly fungicidal or insecticidal activity of the test compounds, care was also taken that the experiments proceeded without fungus infection or insect infestation.
Nach Beendigung der Erholungsphase wurden die Schadintensitäten visuell im Vergleich zu unbehandelten, ungestressten Kontrollen gleichen Alters bonitiert. Die Erfassung der Schadintensität erfolgte zunächst prozentual (100% = Pflanzen sind abgestorben, 0 % = wie Kontrollpflanzen). Aus diesen Werten wurde sodann der Wirkungsgrad der Testverbindungen (= prozentuale Reduktion der Schadintensität durch Substanzapplikation) nach folgender Formel ermittelt: After completion of the recovery phase, the damage intensities were scored visually in comparison to untreated, unstressed controls of the same age. The detection of the damage intensity was initially percentage (100% = plants are dead, 0% = as control plants). From these values, the efficiency of the test compounds (= percentage reduction of the damage intensity by substance application) was then determined according to the following formula:
WG: Wirkungsgrad (%) WG: Efficiency (%)
SWug: Schadwert der unbehandelten, gestressten Kontrolle  SWug: Damage value of untreated, stressed control
SWbg: Schadwert der mit Testverbindung behandelten Pflanzen SWbg: Damage of test compound treated plants
In jedem Versuch wurden pro Kultur und Dosierung 3 Töpfe behandelt und ausgewertet, bei den resultierenden Wirkungsgraden handelte es sich also um Mittelwerte. Die in den unten stehenden Tabellen A-1 bis A-3 angegebenen Werte sind wiederum Mittelwerte aus ein bis drei unabhängigen Versuchen. In each experiment, 3 pots were treated and evaluated per culture and dosage, so the resulting efficiencies were about Averages. The values given in Tables A-1 to A-3 below are again mean values from one to three independent experiments.
Wirkungen ausgewählter Verbindungen der allgemeinen Formel (I) unter Effects of selected compounds of general formula (I) under
Trockenstress: Drought Stress:
Tabelle A-1 Table A-1
Tabelle A-2 Table A-2
Tabelle A-3 Table A-3
In den zuvor genannten Tabellen bedeuten: BRSNS = Brassica napus In the aforementioned tables, BRSNS = Brassica napus
TRZAS = Triticum aestivum TRZAS = Triticum aestivum
ZEAMX = Zea mays ZEAMX = Zea mays
Ähnliche Ergebnisse konnten auch noch mit weiteren Verbindungen der allgemeinen Formel (I) auch bei Applikation auf andere Pflanzenarten erzielt werden. Similar results could also be achieved with other compounds of general formula (I) even when applied to other plant species.

Claims

Patentansprüche claims
1 . Verwendung substituierter 1 -(ArySethiny!)-, 1 -(Heteroarylethinyl)-, 1 - (Heterocyclylethinyl)- und 1 -(Cyioalkenylethinyl)-bicycioalkanole der allgemeinen Formel (I) oder deren Salze zur Erhöhung der Stresstoleranz in Pflanzen gegenüber abiotischem Stress und/oder zur Erhöhung des Pflanzenertrags, 1 . Use of substituted 1 - (ArySethiny!), 1- (heteroarylethynyl) -, 1 - (heterocyclylethynyl) - and 1 - (cyioalkenylethynyl) bicycloalkanols of the general formula (I) or their salts for increasing the stress tolerance in plants to abiotic stress and / or to increase the crop yield,
zur Erhöhung der Stresstoleranz in Pflanzen gegenüber abiotischem Stress und/oder zur Erhöhung des Pflanzenertrags, wobei to increase the stress tolerance in plants to abiotic stress and / or increase plant yield, wherein
[X-Y] für die Gruppierungen [X-Y] for the groupings
[X-Y]1 [X-Y]2 und [x-Y]4 steht, [XY] 1 [XY] 2 and [xY] 4 ,
Q für die Gruppierungen Q-1 bis Q-6 Q for the groupings Q-1 to Q-6
Q-1 Q-2 Q-3 Q-1 Q-2 Q-3
Q-4 , Q-5 und Q-6 steht, wobei R13, R14, R15, R16, R17, R18, R19, R20, R23, R24, R25, R26, R28, R29, R30, R31, R32, R34, R35 und R36 sowie A1 bis A9 jeweils die Bedeutung gemäß der nachstehenden Definitionen haben und wobei der Pfeil für eine Bindung zur jeweiligen Gruppierung C-R6 in der allgemeinen Formel (I) steht, Q-4, Q -5 and Q-6, wherein R 13 , R 14 , R 15 , R 16 , R 17 , R 18 , R 19 , R 20 , R 23 , R 24 , R 25 , R 26 , R 28 , R 29 , R 30 , R 31 , R 32 , R 34 , R 35 and R 36 and A 1 to A 9 are each as defined below and wherein the arrow indicates a bond to the respective grouping CR 6 in the general formula (I) stands,
R1 für Alkyl, Cycloalkyl, Cycloalkenyl, Alkenyl, Alkinyl, Alkenylalkyl, R 1 is alkyl, cycloalkyl, cycloalkenyl, alkenyl, alkynyl, alkenylalkyl,
Alkinylalkyl, Alkoxyalkyl, Hydroxyalkyl, Haloalkyl, Haloalkenyl,  Alkynylalkyl, alkoxyalkyl, hydroxyalkyl, haloalkyl, haloalkenyl,
Haloalkinyl, Haloalkoxyalkyl, Alkoxyhaloalkyl, Haloalkoxyhaloalkyl, Alkylthioalkyl, Haloalkylthioalkyl, Aryl, Heteroaryl, Heterocyclyl steht,  Haloalkynyl, haloalkoxyalkyl, alkoxyhaloalkyl, haloalkoxyhaloalkyl, alkylthioalkyl, haloalkylthioalkyl, aryl, heteroaryl, heterocyclyl,
R2, R3 und R4 unabhängig voneinander für Wasserstoff, Alkyl, Aryl, Heteroaryl, Heterocyclyl, Cycloalkyl, Cycloalkenyl, Alkenyl, Alkinyl, Alkenylalkyl, Alkinylalkyl, Alkoxyalkyl, Hydroxyalkyl, Haloalkyl, Haloalkenyl, R 2 , R 3 and R 4 independently of one another represent hydrogen, alkyl, aryl, heteroaryl, heterocyclyl, cycloalkyl, cycloalkenyl, alkenyl, alkynyl, alkenylalkyl, alkynylalkyl, alkoxyalkyl, hydroxyalkyl, haloalkyl, haloalkenyl,
Haloalkinyl, Haloalkoxyalkyl, Alkoxyhaloalkyl, Haloalkoxyhaloalkyl, Alkylthioalkyl, Haloalkylthioalkyl stehen,  Haloalkynyl, haloalkoxyalkyl, alkoxyhaloalkyl, haloalkoxyhaloalkyl, alkylthioalkyl, haloalkylthioalkyl,
R5 für Hydroxy, Alkoxy, Aryloxy, Cycloalkyloxy, Alkenyloxy, Alkenylalkyloxy, Alkoxyalkyloxy, Alkylcarbonyloxy, Arylcarbonyloxy, R 5 is hydroxy, alkoxy, aryloxy, cycloalkyloxy, alkenyloxy, alkenylalkyloxy, alkoxyalkyloxy, alkylcarbonyloxy, arylcarbonyloxy,
Heteroarylcarbonyloxy, Cycloalkylcarbonyloxy, Alkoxycarbonyloxy, Allyloxycarbonyloxy, Aryloxyalkyloxy, Arylalkyloxy, Alkoxyalkoxyalkyloxy, Alkylthioalkyloxy, Trialkylsilyloxy, Alkyl(Bis-alkyl)silyloxy, Alkyl(Bis- Aryl)silyloxy, Aryl(Bis-alkyl)silyloxy, Cycloalkyl(Bis-alkyl)silyloxy, Halo(Bis- alkyl)silyloxy, Trialkylsilylalkoxyalkyloxy steht,  Heteroarylcarbonyloxy, cycloalkylcarbonyloxy, alkoxycarbonyloxy, allyloxycarbonyloxy, aryloxyalkyloxy, arylalkyloxy, alkoxyalkoxyalkyloxy, alkylthioalkyloxy, trialkylsilyloxy, alkyl (bis-alkyl) silyloxy, alkyl (bis-aryl) silyloxy, aryl (bis-alkyl) silyloxy, cycloalkyl (bis-alkyl) silyloxy, Halo (bis-alkyl) silyloxy, trialkylsilylalkoxyalkyloxy,
R6 für Nitro, Amino, Hydroxy, Hydrothio, Thiocyanato, Isothiocyanato, R 6 is nitro, amino, hydroxy, hydrothio, thiocyanato, isothiocyanato,
Halogen, Alkyl, Cycloalkyl, Alkenyl, Cycloalkenyl, Alkinyl, Arylalkinyl, Trialkylsilylalkinyl, Aryl, Arylalkyl, Arylalkoxy, Heteroaryl, Haloalkyl, Halocycloalkyl, Haloalkenyl, Alkoxy, Haloalkoxy, Aryloxy, Heteroaryloxy, Cycloalkyloxy, Cycloalkylalkoxy, Alkenyloxy, Alkinylalkyloxy, Halogen, alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl, arylalkynyl, trialkylsilylalkynyl, aryl, arylalkyl, arylalkoxy, heteroaryl, haloalkyl, Halocycloalkyl, haloalkenyl, alkoxy, haloalkoxy, aryloxy, heteroaryloxy, cycloalkyloxy, cycloalkylalkoxy, alkenyloxy, alkynylalkyloxy,
Hydroxyalkyl, Alkoxyalkyl, Aryloxyaikyl, Heteroaryioxyalkyl, Aikylthio, Haloalkylthio, Alkoxycarbonylalkylthio, Arylthio, Cycloalkylthio, Hydroxyalkyl, alkoxyalkyl, aryloxyalkyl, heteroaryloxyalkyl, alkylthio, haloalkylthio, alkoxycarbonylalkylthio, arylthio, cycloalkylthio,
Heteroarylthio, Alkyithioalkyl, Alkylamino, Bisalkylamino, Aikenylamino, Cycloalkylamino, Alkylcarbonylamino, Cycloalkylcarbonylamino, Arylcarbonylamino, Heteroarylcarbonylamino, Formylamino, Heteroarylthio, alkylthioalkyl, alkylamino, bisalkylamino, acylamino, cycloalkylamino, alkylcarbonylamino, cycloalkylcarbonylamino, arylcarbonylamino, heteroarylcarbonylamino, formylamino,
Haloalkylcarbonylamino, Alkoxy carbonylamino, Haloalkylcarbonylamino, alkoxycarbonylamino,
Alkylaminocarbonylamino, Alkyl(Alkyl-)aminocarbonylamino, Alkylaminocarbonylamino, alkyl (alkyl) aminocarbonylamino,
Alkylsulfonylamino, Cycloalkylsulfonylamino, Arylsulfonylamino, Hetarylsulfonylamino, Sulfonylhaloalkylamino, Aminoalkylsulfonyl, Aminohaloalkylsulfonyl, Alkylaminosulfonyl, Bisalkylaminosulfonyl, Cycloalkylaminosulfonyl, Haloalkylaminosulfonyl, Alkylsulfonylamino, cycloalkylsulfonylamino, arylsulfonylamino, hetarylsulfonylamino, sulfonylhaloalkylamino, aminoalkylsulfonyl, aminohaloalkylsulfonyl, alkylaminosulfonyl, bisalkylaminosulfonyl, cycloalkylaminosulfonyl, haloalkylaminosulfonyl,
Heteroarylaminosulfonyl, Arylaminosulfonyl, Arylalkylaminosulfonyl, Alkylsulfonyl, Cycloalkylsulfonyl, Arylsulfonyl, Alkylsulfinyl, Heteroarylaminosulfonyl, arylaminosulfonyl, arylalkylaminosulfonyl, alkylsulfonyl, cycloalkylsulfonyl, arylsulfonyl, alkylsulfinyl,
Cycloalkylsulfinyl, Arylsulfinyl, N.S-Dialkylsulfonimidoyl, S- Alkylsulfonimidoyl, Alkylsulfonylaminocarbonyl, Cycloalkylsulfinyl, arylsulfinyl, N.S. dialkylsulfonimidoyl, S-alkylsulfonimidoyl, alkylsulfonylaminocarbonyl,
Cycloalkylsulfonylaminocarbonyl, Arylalkylcarbonylamino, Cycloalkylsulfonylaminocarbonyl, arylalkylcarbonylamino,
Cycloalkylalkylcarbonylamino, Heteroarylcarbonylamino, Cycloalkylalkylcarbonylamino, heteroarylcarbonylamino,
Alkoxyalkylcarbonylamino, Hydroxyalkylcarbonylamino, Alkoxyalkylcarbonylamino, hydroxyalkylcarbonylamino,
Alkoxycarbonylaminoalkylcarbonylamino, Cyano, Cyanoalkyl, Alkoxycarbonylaminoalkylcarbonylamino, cyano, cyanoalkyl,
Hydroxycarbonyl, Alkoxycarbonyl, Cycloalkoxycarbonyl, Hydroxycarbonyl, alkoxycarbonyl, cycloalkoxycarbonyl,
Cycloalkylalkoxycarbonyl, Aryloxycarbonyl, Arylalkoxycarbonyl, Cycloalkylalkoxycarbonyl, aryloxycarbonyl, arylalkoxycarbonyl,
Alkenyloxycarbonyl, Alkinyloxycarbonyl, Haloalkyloxycarbonyl, Alkenyloxycarbonyl, alkynyloxycarbonyl, haloalkyloxycarbonyl,
Alkoxyalkoxycarbonyl, Alkenyloxyalkoxycarbonyl, Alkoxyalkoxycarbonyl, alkenyloxyalkoxycarbonyl,
Alkylaminoalkoxycarbonyl, Trisalkylsilyloxyalkoxycarbonyl, Bis- Alkylaminoalkoxycarbonyl, Alkyl(alkyl)aminoalkoxycarbonyl, Alkylaminoalkoxycarbonyl, trisalkylsilyloxyalkoxycarbonyl, bis-alkylaminoalkoxycarbonyl, alkyl (alkyl) aminoalkoxycarbonyl,
Cyanoalkoxycarbonyl, Heterocyclyl-N-alkoxycarbonyl, Cyanoalkoxycarbonyl, heterocyclyl-N-alkoxycarbonyl,
Heteroaryloxycarbonyl, Heteroarylalkoxycarbonyl, Heteroaryloxycarbonyl, heteroarylalkoxycarbonyl,
Heterocyclylalkoxycarbonyl, Heterocyclyloxycarbonyl, Heterocyclylalkoxycarbonyl, heterocyclyloxycarbonyl,
Alkenylalkoxycarbonyl, Alkinyiaikoxycarbonyl, Arylaikinyloxycarbonyl, Arylalkenyloxycarbonyl, Aminocarbonyl, Alkylaminocarbonyl, Alkenylalkoxycarbonyl, alkynyloxycarbonyl, arylalkynyloxycarbonyl, arylalkenyloxycarbonyl, aminocarbonyl, alkylaminocarbonyl,
Bisalkylaminocarbonyl, Alkyl(Alkyl)aminocarbonyl, Bisalkylaminocarbonyl, alkyl (alkyl) aminocarbonyl,
Alkyl(Alkoxy)aminocarbonyl, Alkenylaminocarbonyl, Cycloalkylaminocarbonyl, Arylaminocarbonyl, Arylalkylaminocarbonyl, Heteroarylalkylaminocarbonyl, Cyanoalkylaminocarbonyl, Alkyl (alkoxy) aminocarbonyl, alkenylaminocarbonyl, Cycloalkylaminocarbonyl, arylaminocarbonyl, arylalkylaminocarbonyl, heteroarylalkylaminocarbonyl, cyanoalkylaminocarbonyl,
Haloalkylaminocarbonyl, Alkinylalkylaminocarbonyl, Haloalkylaminocarbonyl, alkynylalkylaminocarbonyl,
Alkoxycarbonylaminocarbonyl, Arylalkoxycarbonylaminocarbonyl, Hydroxycarbonylalkyl, Alkoxycarbonylalkyl, Cycloalkoxycarbonylalkyl,Alkoxycarbonylaminocarbonyl, arylalkoxycarbonylaminocarbonyl, hydroxycarbonylalkyl, alkoxycarbonylalkyl, cycloalkoxycarbonylalkyl,
Cycloalkylalkoxycarbonylalkyl, Alkenyloxycarbonylalkyl, Cycloalkylalkoxycarbonylalkyl, alkenyloxycarbonylalkyl,
Arylalkoxycarbonylalkyl, Alkylaminocarbonylalkyl, Aminocarbonylalkyl, Bisalkylaminocarbonylalkyl, Cycloalkylaminocarbonylalkyl, Arylalkoxycarbonylalkyl, alkylaminocarbonylalkyl, aminocarbonylalkyl, bisalkylaminocarbonylalkyl, cycloalkylaminocarbonylalkyl,
Arylalkylaminocarbonylalkyl, Heteroarylalkylaminocarbonylalkyl, Arylalkylaminocarbonylalkyl, heteroarylalkylaminocarbonylalkyl,
Cyanoalkylaminocarbonylalkyl, Haloalkylaminocarbonylalkyl, Cyanoalkylaminocarbonylalkyl, haloalkylaminocarbonylalkyl,
Alkinylalkylaminocarbonylalkyl, Cycloalkylalkylaminocarbonylalkyl, Alkynylalkylaminocarbonylalkyl, cycloalkylalkylaminocarbonylalkyl,
Alkoxycarbonylaminocarbonylalkyl, Alkoxycarbonylaminocarbonylalkyl,
Arylalkoxycarbonylaminocarbonylalkyl.  Arylalkoxycarbonylaminocarbonylalkyl.
Alkoxycarbonylalkylaminocarbonyl, Hydroxycarbonylalkylaminocarbonyl, Arylalkoxycarbonylalkylaminocarbonyl,  Alkoxycarbonylalkylaminocarbonyl, hydroxycarbonylalkylaminocarbonyl, arylalkoxycarbonylalkylaminocarbonyl,
Aminocarbonylalkylaminocarbonyl, Aminocarbonylalkylaminocarbonyl,
Alkylaminocarbonylalkylaminocarbonyl, Alkylaminocarbonylalkylaminocarbonyl,
Cycloalkylaminocarbonylalkylaminocarbonyl. Cycloalkylaminocarbonylalkylaminocarbonyl.
Cycloalkylalkylaminocarbonyl, Cycloalkylalkylaminocarbonylalkyl, Cycloalkylalkylaminocarbonylalkylaminocarbonyl, Cycloalkylalkylaminocarbonyl, cycloalkylalkylaminocarbonylalkyl, cycloalkylalkylaminocarbonylalkylaminocarbonyl,
Alkenylalkylaminocarbonyl, Alkenylaminocarbonylalkyl,  Alkenylalkylaminocarbonyl, alkenylaminocarbonylalkyl,
Alkenylalkylaminocarbonylalkyl, Alkylcarbonyl, Cycloalkylcarbonyl, Arylcarbonyl, Formyl, Hydroxyiminomethyl, Aminoiminomethyl, Alkenylalkylaminocarbonylalkyl, alkylcarbonyl, cycloalkylcarbonyl, arylcarbonyl, formyl, hydroxyiminomethyl, aminoiminomethyl,
Alkoxyiminomethyl, Alkylaminoiminomethyl, Dialkyiaminoiminomethyl, Cycioaikoxyiminomethyl, Cycloalkylaikoximinomethyl, Aryioximinomethyl,Alkoxyiminomethyl, Alkylaminoiminomethyl, Dialkyiaminoiminomethyl, Cycioaikoxyiminomethyl, Cycloalkylaikoximinomethyl, Aryioximinomethyl,
Arylalkoxyiminomethyl, Arylalkylaminoiminomethyl, Arylalkoxyiminomethyl, arylalkylaminoiminomethyl,
Alkenyloxyiminomethyl, Arylaminoiminomethyl, Alkenyloxyiminomethyl, arylaminoiminomethyl,
Arylsulfonylaminoiminomethyl, Heteroarylalkyl, Heterocyclylalkyl, Hydroxycarbonylheterocyclyl, Alkoxycarbonylheterocyclyl, Arylsulfonylaminoiminomethyl, heteroarylalkyl, heterocyclylalkyl, hydroxycarbonylheterocyclyl, alkoxycarbonylheterocyclyl,
Alkenyloxycarbonylheterocyclyl, Alkenylalkoxycarbonylheterocyclyl,Alkenyloxycarbonylheterocyclyl, alkenylalkoxycarbonylheterocyclyl,
Arylalkoxycarbonylheterocyclyl, Cycloalkoxycarbonylheterocyclyl, Cycloalkylalkoxycarbonylheterocyclyl, Aminocarbonylheterocyclyl, Alkylaminocarbonylheterocyclyl, Bis-Alkylaminocarbonylheterocyclyl, Cycloalkylaminocarbonylheterocyclyl, Arylalkylaminocarbonylheterocyclyl, Alkenylaminocarbonylheterocyclyl, Hydroxycarbonylheterocyclylalkyl, Alkoxycarbonylheterocyclylalkyl, Hydroxycarbonylcycloalkylalkyl, Alkoxycarbonylcycloalkyialkyl, Arylalkoxycarbonylheterocyclyl, cycloalkoxycarbonylheterocyclyl, cycloalkylalkoxycarbonylheterocyclyl, aminocarbonylheterocyclyl, alkylaminocarbonylheterocyclyl, bis-alkylaminocarbonylheterocyclyl, cycloalkylaminocarbonylheterocyclyl, Arylalkylaminocarbonylheterocyclyl, alkenylaminocarbonylheterocyclyl, hydroxycarbonylheterocyclylalkyl, alkoxycarbonylheterocyclylalkyl, hydroxycarbonylcycloalkylalkyl, alkoxycarbonylcycloalkylalkyl,
Hydroxyaminocarbonyl, Alkoxyaminocarbonyl, Arylalkoxyaminocarbonyl, Heterocyclyl, Alkylcarbonyloxy, Arylcarbonyloxy, Heteroarylcarbonyloxy, Cycloalkylcarbonyloxy, Alkoxycarbonyloxy, Alkenyloxycarbonyloxy, Aminosulfonyl, Aikoxyalkylaminocarbonyi, Alkoxycarbonylheterocyclyl-N- carbonyl, Alkoxycarbonylalkylheterocyclylidenaminocarbonyl,  Hydroxyaminocarbonyl, alkoxyaminocarbonyl, arylalkoxyaminocarbonyl, heterocyclyl, alkylcarbonyloxy, arylcarbonyloxy, heteroarylcarbonyloxy, cycloalkylcarbonyloxy, alkoxycarbonyloxy, alkenyloxycarbonyloxy, aminosulfonyl, aikoxyalkylaminocarbonyi, alkoxycarbonylheterocyclyl-N-carbonyl, alkoxycarbonylalkylheterocyclylidenaminocarbonyl,
Alkoxycarbonylheterocyclylidenalkylaminocarbonyl.  Alkoxycarbonylheterocyclylidenalkylaminocarbonyl.
Alkoxycarbonylalkyl(alkyl)aminocarbonyl.  Alkoxycarbonylalkyl (alkyl) aminocarbonyl.
Alkoxycarbonylcycloalkylidenaminocarbonyl, Heterocyclyl-N-carbonyl steht,  Alkoxycarbonylcycloalkylidene-aminocarbonyl, heterocyclyl-N-carbonyl,
R7, R8, R9, R10, R11 und R12 unabhängig voneinander für Wasserstoff, Alkyl, Cycloalkyl, Alkenyl, Alkenylalkyl, Alkoxyalkyl, Hydroxyalkyl, Haloalkyl, Haloalkenyl, Haloalkoxyalkyl, Alkoxyhaloalkyl, Haloalkoxyhaloalkyl, Alkoxy, Alkylthio, Alkylamino, Halogen, Amino, Aryl, Heteroaryl, R 7 , R 8 , R 9 , R 10 , R 11 and R 12 are each independently hydrogen, alkyl, cycloalkyl, alkenyl, alkenylalkyl, alkoxyalkyl, hydroxyalkyl, haloalkyl, haloalkenyl, haloalkoxyalkyl, alkoxyhaloalkyl, haloalkoxyhaloalkyl, alkoxy, alkylthio, alkylamino, Halogen, amino, aryl, heteroaryl,
Heterocyclyl, Arylthio, Cycloalkylthio, Heterocyclylthio, Alkylsulfinyl, Arylsulfinyl, Heteroarylsulfinyl, Cycloalkylsulfinyl, Heterocyclylsulfinyl, Alkylsulfonyl, Arylsulfonyl, Heteroarylsulfonyl, Cycloalkylsulfonyl, Heterocyclyisuifonyi stehen, wobei mindestens eine der Gruppen R7, R8, R9, R10, R11 und R 2 nicht für Wasserstoff steht und Heterocyclyl, arylthio, cycloalkylthio, heterocyclylthio, alkylsulfinyl, arylsulfinyl, heteroarylsulfinyl, cycloalkylsulfinyl, heterocyclylsulfinyl, alkylsulfonyl, arylsulfonyl, heteroarylsulfonyl, cycloalkylsulfonyl, heterocyclysulfonyl, where at least one of the groups R 7 , R 8 , R 9 , R 10 , R 11 and R 2 does not stand for hydrogen and
R3 und R4 mit dem Atom, an das sie gebunden sind, eine exo-Alkylidengruppe oder einen vollständig gesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 6-gliedrigen Ring bilden, R 3 and R 4 with the atom to which they are attached, an exo-alkylidene group or a fully saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 3 to 6 form a -ligmoid ring,
R1 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig R 1 and R 11 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R1 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel), S=0, S(=0)2 oder eine Gruppierung N-H, N+-R37(-0"), N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7- gliedrigen Ring bilden, form a saturated or partially saturated 5 to 7-membered ring, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted, R 1 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally by O (oxygen), S (sulfur), S = 0, S (= 0) 2 or a group NH, N + R 37 (-0 " ), NR 37 form interrupted and optionally further substituted 3 to 7-membered ring,
R3 und R7 mit den Atomen, an die sie gebunden sind, einen vollständig R 3 and R 7 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel), S=0, S(=0)2 oder eine Gruppierung N-H, N+-R37(-G"), N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7- gliedrigen Ring bilden, saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur), S = 0, S (= 0) 2 or a group NH, N + -R 37 (-G "), NR 37 and optionally further substituted 5 to form a 7-membered ring,
R3 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig R 3 and R 11 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel), S=0, S(=0)2 oder eine Gruppierung N-H, N+-R37(-0 ), N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7- gliedrigen Ring bilden, saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur), S = 0, S (= 0) 2 or a group NH, N + -R 37 (-0), NR 37 and optionally further substituted 3 bis Form a 7-membered ring,
R1 und R3 mit den Atomen, an die sie gebunden sind, einen vollständig R 1 and R 3 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel), S=0, S(=0)2 oder eine Gruppierung N-H, N+-R37(-0"), N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7- gliedrigen Ring bilden, saturated or partially saturated, optionally by O (oxygen), S (sulfur), S = 0, S (= 0) 2 or a group NH, N + -R 37 (-0 " ), NR 37 interrupted and optionally further substituted 5 to form a 7-membered ring,
R7 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig R 7 and R 11 complete with the atoms to which they are attached
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel), S=0, S(=0)2 oder eine Gruppierung N-H, N+-R37(-0'), N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7- gliedrigen Ring bilden, saturated or partially saturated, optionally by O (oxygen), S (sulfur), S = 0, S (= 0) 2 or a group NH, N + -R 37 (-0 ' ), NR 37 interrupted and optionally further substituted 5 to form a 7-membered ring,
R3 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig R 3 and R 9 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel S=0, S(=0)2 oder eine Gruppierung N-H, N+-R37(-0 ), N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7- gliedrigen Ring bilden, saturated or partially saturated, optionally by O (oxygen), S (sulfur S = O, S (= O) 2 or a group NH, N + -R 37 (-O), NR 37 form interrupted and optionally further substituted 3 to 7-membered ring,
R7 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig R 7 and R 9 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel), S=0, S(=0)2 oder eine Gruppierung N-H, N+-R37(-0"), N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7- gliedrigen Ring bilden, saturated or partially saturated, optionally by O (oxygen), S (sulfur), S = 0, S (= 0) 2 or a group NH, N + -R 37 (-0 " ), NR 37 interrupted and optionally further substituted 3 to form a 7-membered ring,
R13, R14, R15 und R16 unabhängig voneinander für Wasserstoff, Halogen, Nitro, Amino, Cyano, Alkyl, Aryl, Heteroaryl, Cycloalkyl, Cycloalkenyl, Alkenyl, Alkinyl, Alkenylalkyl, Alkinylalkyl, Hydroxy, Alkoxy, Alkoxyalkoxy, Alkoxyalkyl, Hydroxyalkyl, Haloalkoxy, Haloalkyl, Haloalkenyl, R 13 , R 14 , R 15 and R 16 are each independently hydrogen, halogen, nitro, amino, cyano, alkyl, aryl, heteroaryl, cycloalkyl, cycloalkenyl, alkenyl, alkynyl, alkenylalkyl, alkynylalkyl, hydroxy, alkoxy, alkoxyalkoxy, alkoxyalkyl, Hydroxyalkyl, haloalkoxy, haloalkyl, haloalkenyl,
Haloalkinyl, Haloalkoxyalkyl, Alkoxyhaloalkyl, Haloalkoxyhaloalkyl, Hydrothio, Alkylthio, Haloalkylthio, Alkylthioalkyl, Haloalkylthioalkyl, Alkylamino, Bisalkylamino, Alkenylamino, Cycloalkylamino,  Haloalkynyl, haloalkoxyalkyl, alkoxyhaloalkyl, haloalkoxyhaloalkyl, hydrothio, alkylthio, haloalkylthio, alkylthioalkyl, haloalkylthioalkyl, alkylamino, bisalkylamino, alkenylamino, cycloalkylamino,
Alkylcarbonylamino, Cycloalkylcarbonylamino, Arylcarbonylamino, Heteroarylcarbonylamino, Formylamino, Haloalkylcarbonylamino, Alkoxycarbonylamino, Alkylaminocarbonylamino, Alkyl(Alkyl)- aminocarbonylamino, Alkylsulfonylamino, Cycloalkylsulfonylamino, Arylsulfonylamino, Hetarylsulfonylamino, Sulfonylhaloalkylamino, Aminoalkylsulfonyl, Aminohaloalkylsulfonyl, Alkylaminosulfonyl, Bisalkylaminosulfonyl, Cycloalkylaminosulfonyl, Haloalkylaminosulfonyl, Heteroarylaminosulfonyl, Arylaminosulfonyl, Arylalkylaminosulfonyl, Alkylsulfonyl, Cycloalkylsulfonyl, Arylsulfonyl, Hydroxycarbonyl, Alkoxycarbonyl, Cycloalkoxycarbonyl, Cycloalkylalkoxycarbonyl, Aryloxycarbonyl, Arylalkoxycarbonyl, Alkenyloxycarbonyl,  Alkylcarbonylamino, cycloalkylcarbonylamino, arylcarbonylamino, heteroarylcarbonylamino, formylamino, Haloalkylcarbonylamino, alkoxycarbonylamino, alkylaminocarbonylamino, alkyl (alkyl) - aminocarbonylamino, alkylsulfonylamino, cycloalkylsulfonylamino, arylsulfonylamino, Hetarylsulfonylamino, Sulfonylhaloalkylamino, Aminoalkylsulfonyl, Aminohaloalkylsulfonyl, alkylaminosulfonyl, Bisalkylaminosulfonyl, Cycloalkylaminosulfonyl, Haloalkylaminosulfonyl, heteroarylaminosulfonyl, arylaminosulfonyl, Arylalkylaminosulfonyl , Alkylsulfonyl, cycloalkylsulfonyl, arylsulfonyl, hydroxycarbonyl, alkoxycarbonyl, cycloalkoxycarbonyl, cycloalkylalkoxycarbonyl, aryloxycarbonyl, arylalkoxycarbonyl, alkenyloxycarbonyl,
Alkinyloxycarbonyl, Aminocarbonyl, Alkylaminocarbonyl,  Alkynyloxycarbonyl, aminocarbonyl, alkylaminocarbonyl,
Bisalkylaminocarbonyl, Alkyl(Alkyl)aminocarbonyl,  Bisalkylaminocarbonyl, alkyl (alkyl) aminocarbonyl,
Alkyl(Alkoxy)aminocarbonyl, Alkenylaminocarbonyl,  Alkyl (alkoxy) aminocarbonyl, alkenylaminocarbonyl,
Cycloalkylaminocarbonyl, Arylaminocarbonyl, Arylalkylaminocarbonyl, Heterocyclyl, Arylthio, Cycloalkylthio, Heterocyclylthio, Alkylsulfinyl, Arylsulfinyl, Heteroarylsulfinyl, Cycloalkylsulfinyl, Heterocyclylsulfinyl, Heteroarylsulfonyl, Heterocyclylsulfonyl stehen, A\ A2, A3 und A4 gleich oder verschieden sind und unabhängig voneinander für N (Stickstoff) oder die Gruppierungen C-H, C-CH3, C-F, C-Cl, C-Br, C-l, C-OCF3, C-OCH3, C-CF3, C-CO2H, C-CO2CH3 stehen, wobei jedoch in keinem Fall mehr als zwei N-Atome benachbart sind, Cycloalkylaminocarbonyl, arylaminocarbonyl, arylalkylaminocarbonyl, heterocyclyl, arylthio, cycloalkylthio, heterocyclylthio, alkylsulfinyl, arylsulfinyl, heteroarylsulfinyl, cycloalkylsulfinyl, heterocyclylsulfinyl, heteroarylsulfonyl, heterocyclylsulfonyl, A \ A 2 , A 3 and A 4 are identical or different and represent, independently of one another, N (nitrogen) or the groupings CH, C-CH 3 , CF, C-Cl, C-Br, Cl, C-OCF 3, C- OCH3, C-CF3, C-CO2H, C-CO2CH3, but in no case more than two N atoms are adjacent,
R17 und R18 unabhängig voneinander für Wasserstoff, Halogen, Alkyl, Aryl,R 17 and R 18 independently of one another represent hydrogen, halogen, alkyl, aryl,
Heteroaryl, Heterocyclyl, Cycloalkyl, Alkenyl, Alkinyl, Alkoxy, Alkoxyalkyl, Aryloxyalkyl, Haloalkoxy, Haloalkyl, Haloalkoxyalkyl, Alkoxyhaloalkyl, Haloalkoxyhaloalkyl, Alkylthio, Haloalkylthio, Alkylthioalkyl, Heteroaryl, heterocyclyl, cycloalkyl, alkenyl, alkynyl, alkoxy, alkoxyalkyl, aryloxyalkyl, haloalkoxy, haloalkyl, haloalkoxyalkyl, alkoxyhaloalkyl, haloalkoxyhaloalkyl, alkylthio, haloalkylthio, alkylthioalkyl,
Hydroxycarbonyl, Alkoxycarbonyl, Cycloalkoxycarbonyl,  Hydroxycarbonyl, alkoxycarbonyl, cycloalkoxycarbonyl,
Cycloalkylalkoxycarbonyl, Aryloxycarbonyl, Arylalkoxycarbonyl,  Cycloalkylalkoxycarbonyl, aryloxycarbonyl, arylalkoxycarbonyl,
Alkenyloxycarbonyl, Alkinyloxycarbonyl, Aminocarbonyl,  Alkenyloxycarbonyl, alkynyloxycarbonyl, aminocarbonyl,
Alkylaminocarbonyl, Bisalkylaminocarbonyl, Alkyl(Alkyl)aminocarbonyl, Alkyl(Alkoxy)aminocarbonyl, Alkenylaminocarbonyl,  Alkylaminocarbonyl, bisalkylaminocarbonyl, alkyl (alkyl) aminocarbonyl, alkyl (alkoxy) aminocarbonyl, alkenylaminocarbonyl,
Cycloalkylaminocarbonyl, Arylaminocarbonyl, Arylalkylaminocarbonyl stehen,  Cycloalkylaminocarbonyl, arylaminocarbonyl, arylalkylaminocarbonyl,
A5 für S (Schwefel), O (Sauerstoff) oder die Gruppierungen N-H, N-CH3, N- CH2CH3, N-CH(CH3)2, N-C02t-Bu, N-Aryl, N-Heteroaryl, N-Heterocyclyl steht. A 5 represents S (sulfur), O (oxygen) or the groupings NH, N-CH 3 , N-CH 2 CH 3 , N-CH (CH 3 ) 2, N-CO 2 t-Bu, N-aryl, N-heteroaryl, N-heterocyclyl is.
R19, R20, R23 und R24 unabhängig voneinander für Wasserstoff, Alkyl, Halogen, Cycloalkyl, Aryl, Heteroaryl, Heterocyclyl, Alkenyl, Alkenylalkyl, Arylalkyl, Alkoxy, Alkoxyalkoxy, Alkoxyalkyl, Hydroxy, Haloalkyl, Haloalkylthio stehen, R 19 , R 20 , R 23 and R 24 are each independently hydrogen, alkyl, halogen, cycloalkyl, aryl, heteroaryl, heterocyclyl, alkenyl, alkenylalkyl, arylalkyl, alkoxy, alkoxyalkoxy, alkoxyalkyl, hydroxy, haloalkyl, haloalkylthio,
R19 und R23 mit den Atomen, an die sie gebunden sind, einen vollständig R 19 and R 23 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden,  form a saturated or partially saturated, optionally further substituted 5 to 7-membered ring,
A6, A7 gleich oder verschieden sind und unabhängig voneinander für O A 6 , A 7 are the same or different and are each independently O.
(Sauerstoff), S (Schwefel), S=0, S(=0)2, N-H, N+-CH3(-0 ), N-OCH3, N- CH3 oder die Gruppierung CR21R22 stehen, wobei jedoch in keinem Fall zwei N-, O- oder S-Atome benachbart sind, und wobei R21 und R22 in der Gruppierung CR21R22 jeweils gleiche oder verschiedene Bedeutungen gemäß der nachstehenden Definition haben und (Oxygen), S (sulfur), S = 0, S (= 0) 2, NH, N + -CH 3 (-0), N-OCH 3, N-CH3 or the group CR 21 R 22, but using in no case two N, O or S atoms are adjacent, and wherein R 21 and R 22 in the group CR 21 R 22 each have the same or different meanings as defined below, and
R21 und R22 unabhängig voneinander für Wasserstoff, Halogen, Alkyl, Aryl, Heteroaryl, Heterocyclyl, Cycloalkyl, Alkenyl, Alkoxy, Alkoxyalkyl, Aryloxyalkyl, Haloalkoxy, Haloalkyl, Haloalkoxyalkyl, Alkoxyhaloalkyl, Haloalkoxyhaloalkyl, Alkylthio, Haloalkylthio, Alkylthioalkyl, R 21 and R 22 independently of one another represent hydrogen, halogen, alkyl, aryl, heteroaryl, heterocyclyl, cycloalkyl, alkenyl, alkoxy, alkoxyalkyl, aryloxyalkyl, haloalkoxy, haloalkyl, haloalkoxyalkyl, alkoxyhaloalkyl, haloalkoxyhaloalkyl, alkylthio, haloalkylthio, alkylthioalkyl,
Hydroxycarbonyl, Alkoxycarbonyl, Cycloalkoxycarbonyl,  Hydroxycarbonyl, alkoxycarbonyl, cycloalkoxycarbonyl,
Cycloalkylalkoxycarbonyl, Aryloxycarbonyl, Arylalkoxycarbonyl,  Cycloalkylalkoxycarbonyl, aryloxycarbonyl, arylalkoxycarbonyl,
Alkenyloxycarbonyl, Alkinyloxycarbonyl, Aminocarbonyl,  Alkenyloxycarbonyl, alkynyloxycarbonyl, aminocarbonyl,
Alkylaminocarbonyl, Bisalkylaminocarbonyl, Alkyl(Alkyl)aminocarbonyl, Alkyl(Alkoxy)aminocarbonyl, Alkenylaminocarbonyl,  Alkylaminocarbonyl, bisalkylaminocarbonyl, alkyl (alkyl) aminocarbonyl, alkyl (alkoxy) aminocarbonyl, alkenylaminocarbonyl,
Cycloalkylaminocarbonyl, Arylaminocarbonyl, Arylalkylaminocarbonyl, Amino, Alkylamino, Cycloalkylamino, Bis-Alkylamino stehen,  Cycloalkylaminocarbonyl, arylaminocarbonyl, arylalkylaminocarbonyl, amino, alkylamino, cycloalkylamino, bis-alkylamino,
R25, R26, R28 und R29 unabhängig voneinander für Wasserstoff, Alkyl, Halogen, Cycloalkyl, Aryl, Heteroaryl, Heterocyclyl, Alkenyl, Arylalkyl, Alkoxy, Alkoxyalkoxy, Alkoxyalkyl, Haloalkyl stehen, R 25 , R 26 , R 28 and R 29 independently represent hydrogen, alkyl, halogen, cycloalkyl, aryl, heteroaryl, heterocyclyl, alkenyl, arylalkyl, alkoxy, alkoxyalkoxy, alkoxyalkyl, haloalkyl,
A8 für O (Sauerstoff), S (Schwefel), S=0, S(=0)2, N-H, N+-CH3(-0 ), N-CH3, N- OCH3 oder die Gruppierung CHR27 steht und wobei R27 in der A 8 is O (oxygen), S (sulfur), S = O, S (= O) 2 , NH, N + -CH 3 (-O), N-CH 3 , N-OCH 3 or the moiety CHR 27 and wherein R 27 in the
Gruppierung CHR27 die Bedeutung gemäß der nachstehenden Definition hat. Grouping CHR 27 has the meaning as defined below.
R27 für Wasserstoff, Halogen, Alkyl, Aryl, Heteroaryl, Heterocyclyl, Cycloalkyl, Alkenyl, Alkoxy, Alkoxyalkyl, Aryloxyalkyl, Haloalkoxy, Haloalkyl, Alkoxyhaloalkyl, Haloalkoxyhaloalkyl, Alkylthio, Haloalkylthio, R 27 is hydrogen, halogen, alkyl, aryl, heteroaryl, heterocyclyl, cycloalkyl, alkenyl, alkoxy, alkoxyalkyl, aryloxyalkyl, haloalkoxy, haloalkyl, alkoxyhaloalkyl, haloalkoxyhaloalkyl, alkylthio, haloalkylthio,
Alkylthioalkyl, Hydroxycarbonyl, Alkoxycarbonyl, Cycloalkoxycarbonyl, Arylalkoxycarbonyl, Alkenyloxycarbonyl, Alkinyloxycarbonyl,  Alkylthioalkyl, hydroxycarbonyl, alkoxycarbonyl, cycloalkoxycarbonyl, arylalkoxycarbonyl, alkenyloxycarbonyl, alkynyloxycarbonyl,
Aminocarbonyl, Alkylaminocarbonyl, Bisalkylaminocarbonyl,  Aminocarbonyl, alkylaminocarbonyl, bisalkylaminocarbonyl,
Alkyl(Alkyl)aminocarbonyl, Alkyl(Alkoxy)aminocarbonyl,  Alkyl (alkyl) aminocarbonyl, alkyl (alkoxy) aminocarbonyl,
Alkenylaminocarbonyl, Cycloalkylaminocarbonyl, Arylaminocarbonyl, Arylalkylaminocarbonyl, Amino, Alkylamino, Cycloalkylamino, Bis- Alkylamino steht, Alkenylaminocarbonyl, cycloalkylaminocarbonyl, arylaminocarbonyl, Arylalkylaminocarbonyl, amino, alkylamino, cycloalkylamino, bisalkylamino,
R30, R31, R32, R34, R35 und R36 unabhängig voneinander für Wasserstoff, Alkyl, Halogen, Cycioalkyl, Aryl, Heteroaryl, Heterocyclyl, Alkenyl, Alkoxy, Alkoxyalkoxy, Alkoxyalkyl, Haloalkyl, Alkylthio, Haloalkylthio stehen, R 30 , R 31 , R 32 , R 34 , R 35 and R 36 independently of one another represent hydrogen, alkyl, halogen, cycioalkyl, aryl, heteroaryl, heterocyclyl, alkenyl, alkoxy, alkoxyalkoxy, alkoxyalkyl, haloalkyl, alkylthio, haloalkylthio,
A9 für O (Sauerstoff), S (Schwefel), S=0, S(=0)2, N-H, N+-CH3(-0 ), N-CH3, N- OCH3 oder die Gruppierung CHR33 steht und wobei R33 in der Gruppierung CHR33 die Bedeutung gemäß der nachstehenden Definition hat und A 9 is O (oxygen), S (sulfur), S = O, S (= O) 2 , NH, N + -CH 3 (-O), N-CH 3 , N-OCH 3 or the moiety CHR 33 and wherein R 33 in the grouping CHR 33 has the meaning as defined below, and
R33 für Wasserstoff, Halogen, Alkyl, Aryl, Heteroaryl, Heterocyclyl, Cycioalkyl, Alkenyl, Alkoxy, Alkoxyalkyl, Aryloxyalkyl, Haloalkoxy, Haloalkyl, R 33 is hydrogen, halogen, alkyl, aryl, heteroaryl, heterocyclyl, cycloalkyl, alkenyl, alkoxy, alkoxyalkyl, aryloxyalkyl, haloalkoxy, haloalkyl,
Alkylthio, Haloalkylthio, Hydroxycarbonyl, Alkoxycarbonyl, Cycloalkoxycarbonyl, Arylalkoxycarbonyl, Alkenyloxycarbonyl, Alkinyloxycarbonyl, Aminocarbonyl, Alkylaminocarbonyl,  Alkylthio, haloalkylthio, hydroxycarbonyl, alkoxycarbonyl, cycloalkoxycarbonyl, arylalkoxycarbonyl, alkenyloxycarbonyl, alkynyloxycarbonyl, aminocarbonyl, alkylaminocarbonyl,
Bisalkylaminocarbonyl, Alkyl(Alkyl)aminocarbonyl,  Bisalkylaminocarbonyl, alkyl (alkyl) aminocarbonyl,
Alkyl(Alkoxy)aminocarbonyl, Alkenylaminocarbonyl,  Alkyl (alkoxy) aminocarbonyl, alkenylaminocarbonyl,
Cycloalkylaminocarbonyl, Arylaminocarbonyl, Arylalkylaminocarbonyl, Amino, Alkylamino, Cycloalkylamino, Bis-Alkylamino steht,  Cycloalkylaminocarbonyl, arylaminocarbonyl, arylalkylaminocarbonyl, amino, alkylamino, cycloalkylamino, bis-alkylamino,
R37 für Alkyl, Aryl, Heteroaryl, Heterocyclyl, Cycioalkyl, Alkenyl, Alkoxy, R 37 is alkyl, aryl, heteroaryl, heterocyclyl, cycloalkyl, alkenyl, alkoxy,
Alkoxyalkyl, Aryloxyalkyl, Alkoxycarbonyl, Cycloalkoxycarbonyl,  Alkoxyalkyl, aryloxyalkyl, alkoxycarbonyl, cycloalkoxycarbonyl,
Arylalkoxycarbonyl, Alkenyloxycarbonyl, Alkinyloxycarbonyl, Alkylcarbonyl, Cycloalkylcarbonyl, Arylcarbonyi, Heteroarylcarbonyl steht.  Arylalkoxycarbonyl, alkenyloxycarbonyl, alkynyloxycarbonyl, alkylcarbonyl, cycloalkylcarbonyl, arylcarbonyi, heteroarylcarbonyl.
2. Verwendung gemäß Anspruch 1 , wobei in Formel (I) 2. Use according to claim 1, wherein in formula (I)
[X-Y] für die Gruppierungen [XY] for the groupings
steht, wobei R13, R14, R15, R16, R17, R18, R19, R20, R23, R24, R25, R26, R28, R29, R30, R31, R32, R34, R35 und R36 sowie A1 bis A9 jeweils die Bedeutung gemäß der nachstehenden Definitionen haben und wobei der Pfeil für eine Bindung zur jeweiligen Gruppierung C-R6 in der allgemeinen Formel (I) steht, where R 13 , R 14 , R 15 , R 16 , R 17 , R 18 , R 19 , R 20 , R 23 , R 24 , R 25 , R 26 , R 28 , R 29 , R 30 , R 31 , R 32 , R 34 , R 35 and R 36, and A 1 to A 9 are each as defined below and wherein the arrow represents a bond to the respective group CR 6 in the general formula (I),
R1 für (Ci-Ce)-Alkyl, (C3-C8)-Cycloalkyl, (C4-C8)-Cycloalkenyl, (C2-C8)- Alkenyl, (C2-C8)-Alkinyl, (C2-C8)-Alkenyl-(Ci-C8)-alkyl, (C2-C8)-Alkinyl- (Ci-Cs)-alkyl, (Ci-C8)-Alkoxy-(CrC8)-alkyl, Hydroxy-(d-C8)-alkyl, (Ci-C8)- Haloalkyl, (C2-C8)-Haloalkenyl, (C2-C8)-Haloalkinyl, (Ci-C8)-Haloalkoxy- (Ci-Cs)-alkyl, (Ci-C8)-Alkoxy-(CrC8)-haloalkyl, (d-C8)-Haloalkoxy- (Ci-Ce)-haloalkyl, (Ci-C8)-Alkylthio-(Ci-C8)-alkyl, (Ci-Ce)-Haloalkylthio- (Ci-Cs)-alkyl, Aryl, Heteroaryl, Heterocyclyl steht, R 1 is (C 1 -C 6 ) -alkyl, (C 3 -C 8 ) -cycloalkyl, (C 4 -C 8 ) -cycloalkenyl, (C 2 -C 8 ) -alkenyl, (C 2 -C 8 ) -alkynyl , (C 2 -C 8) alkenyl (Ci-C 8) alkyl, (C 2 -C 8) alkynyl (Ci-Cs) alkyl, (Ci-C 8) alkoxy (CrC 8 ) alkyl, hydroxy (dC 8) alkyl, (Ci-C 8) - haloalkyl, (C2-C8) -haloalkenyl, (C 2 -C 8) haloalkynyl, (Ci-C8) haloalkoxy (Ci-Cs) alkyl, (Ci-C 8) alkoxy (CrC 8) -haloalkyl, (dC 8) haloalkoxy (Ci-Ce) -haloalkyl, (Ci-C8) alkylthio (C C 8 ) -alkyl, (C 1 -C 6 ) -haloalkylthio (C 1 -C 8 ) -alkyl, aryl, heteroaryl, heterocyclyl,
R2, R3 und R4 unabhängig voneinander für Wasserstoff, Halogen, (Ci-C8)-Alkyl, (C3-C8)-Cycloalkyl, (C4-C8)-Cycloalkenyl, (C2-C8)-Alkenyl, (C2-C8)-Alkinyl, (C2-C8)-Alkenyl-(CrC8)-alkyl, (C2-C8)-Alkinyl-(d-C8)-alkyl, (d-C8)- Alkoxy-(Ci-C8)-alkyl, Hydroxy-(Ci-C8)-alkyl, (Ci-Ce)-Haloalkyl, (C -Cs)- Haloalkenyl, (C2-C8)-Haloalkinyl, (Ci-C8)-Haloalkoxy-(Ci-C8)-alkyl, (Ci-C8)-A!koxy-(Ci-C8)-haloalkyl, (Ci-C8)-Haloalkoxy-(CrC8)-haloalkyl, (Ci-C8)-Alkylthio-(Ci-C8)-alkyl, (CrC8)-Haloalkylthio-(Ci-C8)-alkyl, Aryl, Heteroaryl, Heterocyclyl stehen, R 2, R 3 and R 4 are independently hydrogen, halogen, (Ci-C 8) -alkyl, (C 3 -C 8) cycloalkyl, (C 4 -C 8) -cycloalkenyl, (C 2 -C 8 ) alkenyl, (C 2 -C 8) -alkynyl, (C 2 -C 8) alkenyl (-C 8) alkyl, (C 2 -C 8) alkynyl (dC 8) alkyl, (dC 8 ) - Alkoxy (Ci-C 8) alkyl, hydroxy (Ci-C 8) alkyl, (Ci-Ce) -haloalkyl, (C -Cs) - haloalkenyl, (C 2 -C 8) haloalkynyl, (C ! -C 8) haloalkoxy (Ci-C 8) alkyl, (Ci-C 8) -A alkoxy- (Ci-C8) -haloalkyl, (Ci-C8) haloalkoxy (CRC 8) - haloalkyl, (C 1 -C 8 ) -alkylthio (C 1 -C 8 ) -alkyl, (C 1 -C 8 ) -haloalkylthio (C 1 -C 8 ) -alkyl, aryl, heteroaryl, heterocyclyl,
R5 für Hydroxy, (d-C8)-Alkoxy, Aryloxy, (C3-C8)-Cycloalkyloxy, (C2-C8)- Alkenyloxy, (C2-C8)-Alkeny!-(Ci-C8)-alkyloxy. (Ci-C8)-Alkoxy-(Ci-C8)- alkyloxy, (Ci-Cs)-Alkylcarbonyloxy, Arylcarbonyloxy, R 5 is hydroxy, (DC 8) alkoxy, aryloxy, (C 3 -C 8) cycloalkyloxy, (C 2 -C 8) - alkenyloxy, (C2-C8) -Alkeny - (Ci-C 8) alkyloxy. (C 1 -C 8 ) -alkoxy- (C 1 -C 8 ) -alkyloxy, (C 1 -C 8 ) -alkylcarbonyloxy, arylcarbonyloxy,
Heteroarylcarbonyloxy, (C3-C8)-Cycloalkylcarbonyloxy, (Ci-Cs)- Alkoxycarbonyloxy, (C2-C8)-Alkenyloxycarbonyloxy, Aryloxy-(d-C8)- alkyloxy, Aryl-(d-C8)-alkyloxy, (Ci-C8)-Alkoxy-(Ci-C8)-alkoxy-(Ci-C8)- alkyloxy, (CrC8)-Alkylthio-(Ci-C8)-alkyloxy, Tris[(Ci-C8)-alkyl]silyloxy, (Ci-C8)-Alkyl-Bis[(CrC8)-alkyl]silyloxy, (d-C8)-Alkyl-bis(Aryl)silyloxy, Aryl-bis[(Ci-C8)— alkyijsilyloxy, Cycloalkyl-bis[(CrC8)-alkyl]silyloxy, Halo- bis[(Ci-C8)-alkyl]silyloxy, Tris[(Ci-C8)-alkyl]silyl-(Ci-C8)-alkoxy-(CrC8)- alkyloxy, steht, Heteroarylcarbonyloxy, (C3-C8) cycloalkylcarbonyloxy, (Ci-Cs) - alkoxycarbonyloxy, (C2-C8) -Alkenyloxycarbonyloxy, aryloxy (dC 8) - alkyloxy, aryl (dC 8) alkyloxy, (Ci-C 8) alkoxy- (Ci-C 8) alkoxy (Ci-C 8) - alkyloxy, (CrC 8) alkylthio (Ci-C8) alkyloxy, tris [(Ci-C 8) alkyl] silyloxy, (Ci-C 8 ) alkyl bis [(CrC 8 ) alkyl] silyloxy, (dC 8 ) alkyl bis (aryl) silyloxy, aryl bis [(Ci-C 8 ) alkyijsilyloxy, cycloalkyl bis [(CrC 8 ) alkyl] silyloxy, halo bis [(C 1 -C 8 ) alkyl] silyloxy, tris [(C 1 -C 8 ) alkyl] silyl (C 1 -C 8 ) alkoxy (CrC 8 ) - alkyloxy,
R6 für Nitro, Amino, Hydroxy, Hydrothio, Thiocyanato, Isothiocyanato, R 6 is nitro, amino, hydroxy, hydrothio, thiocyanato, isothiocyanato,
Halogen, (Ci-Cs)-Alkyl, (C3-C8)-Cyc!oalkyl, (C2-C8)-Alkenyl, (C4-C8)- Cycloalkenyl, (C2-C8)-Alkinyl, Aryl-(C2-C8)-alkinyl, Tris[(CrC8)-aikyl]silyl- (C2-C8)-alkinyl, Aryl, Aryl-(Ci-C8)-alkyl, Aryl-(Ci-C8)-alkoxy, Heteroaryl, (Ci-C8)-Haloalkyl, (C3-C8)-Halocycloalkyl, (C2-C8)-Haloalkenyl, (d-C8)- Alkoxy, (d-C8)-Haloalkoxy, Aryloxy, Heteroaryloxy, (Cs-Ce)- Cycloalkyloxy, (C3-C8)-Cycloalkyl-(Ci-C8)-alkoxy, (C2-C8)- (C2-C8)- Alkenyloxy, (C2-C8)-Alkinyl-(C2-C8)-alkyloxy, Hydroxy-(d-C8)-alkyl, Halogen, (C 1 -C 8 ) -alkyl, (C 3 -C 8 ) -cycloalkyl, (C 2 -C 8 ) -alkenyl, (C 4 -C 8 ) -cycloalkenyl, (C 2 -C 8 ) -alkynyl , aryl (C 2 -C 8) -alkynyl, tris [(-C 8) -alkyl] silyl (C 2 -C 8) alkynyl, aryl, aryl (Ci-C 8) alkyl, aryl ( Ci-C 8 ) -alkoxy, heteroaryl, (Ci-C 8 ) -haloalkyl, (C 3 -C 8 ) -halocycloalkyl, (C 2 -C 8 ) -haloalkenyl, (dC 8 ) -alkoxy, (dC 8 ) haloalkoxy, aryloxy, heteroaryloxy, (Cs-Ce) - cycloalkyloxy, (C3-C8) -cycloalkyl- (Ci-C8) alkoxy, (C 2 -C 8) - (C 2 -C 8) - alkenyloxy , (C 2 -C 8 ) -alkynyl (C 2 -C 8 ) -alkyloxy, hydroxy (C 1 -C 8 ) -alkyl,
(Ci-C8)-Alkoxy-(Ci-C8)-alkyl, Aryloxy-(Ci-C8)-alkyl, Heteroaryloxy-(Ci-C8)- alkyl, (Ci-C8)-Alkylthio, (Ci-Cs)-Haloalkylthio, (Ci-Cs)-Alkoxycarbonyl- (Ci-C8)-alkylthio, Arylthio, (C3-C8)-Cycloalkylthio, Heteroarylthio, (Ci-C8)- Alkylthio-(CrC8)-alkyl, (Ci-Cs)-Alkylamino, Bis[(Ci-C8)-alkyl]amino, (C2-C8)-Alkenylamino, (C3-C8)-Cycloalkylamino, (Ci-C8)- Alkylcarbonylamino, (C3-C8)-Cycloalkylcarbonylamino, (Ci-C 8) alkoxy (Ci-C 8) alkyl, aryloxy (Ci-C8) alkyl, heteroaryloxy- (Ci-C 8) - alkyl, (Ci-C8) alkylthio, ( Ci-Cs) haloalkylthio, (Ci-Cs) -alkoxycarbonyl (Ci-C8) alkylthio, arylthio, (C 3 -C 8) cycloalkylthio, heteroarylthio, (Ci-C 8) - alkylthio (CrC 8 ) alkyl, (Ci-Cs) alkylamino, bis [(Ci-C 8) alkyl] amino, (C2 -C8) -alkenylamino, (C 3 -C 8) cycloalkylamino, (Ci-C 8 ) - alkylcarbonylamino, (C 3 -C 8 ) -cycloalkylcarbonylamino,
Arylcarbonylamino, Heteroarylcarbonylamino, Formylamino, (d-C8)- Haloalkylcarbonylamino, (CrC8)-Alkoxycarbonylamino, (d-C8)- Alkylaminocarbonylamino, (Ci-C8)-Alkyl[(Ci-C-8)- Alkyl]aminocarbonylamino, (Ci-C8)-Alkylsulfonylamino, (Ca-Cs)- Cycloalkylsulfonylamino, Arylsulfonylamino, Hetarylsulfonylamino, Sulfonyl-(Ci-C8)-haloalkylamino, Amino-(Ci-C8)-alkylsulfonyl, Amino- (Ci-C8)-haloalkylsulfonyl, (Ci-C8)-Alkylaminosulfonyl, Bis[(Ci-C8)- alkyl]aminosulfonyl, (C3-C8)-Cycloalkylaminosulfonyl, (C-i-Cs)- Haloalkylaminosulfonyl, Heteroarylaminosulfonyl, Arylaminosulfonyl, Aryl- (Ci-C8)-alkylaminosulfonyl, (Ci-Ce)-Alkylsulfonyl, (C3-C8)- Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C8)-Alkylsulfinyl, (C3-Cs)- Cycloalkylsulfinyl, Arylsulfinyl, N,S-Bis[(Ci-C8)-alkyl]sulfonimidoyl, S- (CrC8)-Alkylsulfonimidoyl, (Ci-Cs)- Alkylsulfonylaminocarbonyl, (Ca-Ce)- Cycloalkylsulfonylaminocarbonyl, Aryl-(Ci-Ce)-alkylcarbonylamino, (C3-C8)-Cycloalkyl-(Ci-C8)-alkylcarbonylamino, Heteroaryicarbonylamino, (Ci-C8)-Alkoxy-(CrC8)-alkylcarbonylamino, Hydroxy-(Ci-C8)- alkylcarbonylamino, (Ci-C8)-Alkoxycarbonylamino-(Ci-C8)- alkylcarbonylamino, Cyano, Cyano-(d-C8)-alkyl, Hydroxycarbonyl, (d-C8)-Alkoxycarbonyl, (C3-C8)-Cycloalkoxycarbonyl, (Cs-CsJ-Cycloalkyl- (Ci-Ce)-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-Ce)-alkoxycarbonyl, (C2-C8)-Alkenyloxycarbonyl, (C2-C8)-Alkinyloxycarbonyl, (Ci-Cs)- Haloalkyloxycarbonyl, (Ci-C8)-Alkoxy-(Ci-Ce)-alkoxycarbonyl, (C2-Cs)- Alkenyloxy-(d-C8)-alkoxycarbonyl, (Ci-C8)-Alkylamino-(Ci-C8)- alkoxycarbonyl, Tris[(Ci-C8)-alkyl]silyloxy-(Ci-C8)-alkoxycarbonyl, Bis[(Ci-C8)-Alkyl]amino-(Ci-C8)-alkoxycarbonyl, (Ci-C8)-Alkyl[(Ci-C8)- alkyl]amino-(Ci-C8)-alkoxycarbonyl, Cyano-(d-C8)-alkoxycarbonyl, Heterocyclyl-N-(Ci-C8)-alkoxycarbonyl, Heteroaryloxycarbonyl, Arylcarbonylamino, heteroarylcarbonylamino, formylamino, (dC 8 ) - haloalkylcarbonylamino, (CrC 8 ) -alkoxycarbonylamino, (dC 8 ) - Alkylaminocarbonylamino, (C 1 -C 8) -alkyl [(C 1 -C 8) -alkyl] aminocarbonylamino, (C 1 -C 8) -alkylsulfonylamino, (C 1 -C 8) -cycloalkylsulfonylamino, arylsulfonylamino, hetarylsulfonylamino, sulfonyl- (C 1 -C 8) - haloalkylamino, amino- (C 1 -C 8 ) -alkylsulfonyl, amino- (C 1 -C 8 ) -haloalkylsulfonyl, (C 1 -C 8 ) -alkylaminosulfonyl, bis [(C 1 -C 8 ) -alkyl] aminosulfonyl, (C 3 -C 8 ) -Cycloalkylaminosulfonyl, (Ci-Cs) - Haloalkylaminosulfonyl, heteroarylaminosulfonyl, arylaminosulfonyl, aryl (Ci-C 8 ) -alkylaminosulfonyl, (Ci-Ce) alkylsulfonyl, (C 3 -C 8 ) - cycloalkylsulfonyl, arylsulfonyl, (Ci-C8 ) -Alkylsulfinyl, (C3-Cs) -cycloalkylsulfinyl, arylsulfinyl, N, S-bis [(Ci-C8) -alkyl] sulfonimidoyl, S- (CrC8) -alkylsulfonimidoyl, (Ci-Cs) -alkylsulfonylaminocarbonyl, (Ca-Ce ) - cycloalkylsulfonylaminocarbonyl, aryl- (Ci-Ce) -alkylcarbonylamino, (C3-C8) -cycloalkyl- (Ci-C8) -alkylcarbonylamino, heteroaryicarbonylamino, (Ci-C8) -alkoxy- (CrC8) -alkylcarbonylamino, hydroxy- (Ci -C 8) - alkylcarbonylamino, (C 1 -C 8) -alkoxycarbonylamino- (C 1 -C 8) -alkylcarb onylamino, cyano, cyano- (C 1 -C 8) -alkyl, hydroxycarbonyl, (C 1 -C 8) -alkoxycarbonyl, (C 3 -C 8) -cycloalkoxycarbonyl, (C 5 -C 8 -cycloalkyl- (C 1 -C 6) -alkoxycarbonyl, aryloxycarbonyl, aryl (C 1 -C 6) -alkoxycarbonyl, (C 2 -C 8) -alkenyloxycarbonyl, (C 2 -C 8) -alkynyloxycarbonyl, (C 1 -C 8) -haloalkyloxycarbonyl, (C 1 -C 8) -alkoxy- (C 1 -C 6) -alkoxycarbonyl, ( C2-Cs) - alkenyloxy- (C 1 -C 8) -alkoxycarbonyl, (C 1 -C 8) -alkylamino- (C 1 -C 8) -alkoxycarbonyl, tris [(C 1 -C 8) -alkyl] silyloxy- (C 1 -C 8) -alkoxycarbonyl , bis [(Ci-C 8) alkyl] amino- (Ci-C8) alkoxycarbonyl, (Ci-C 8) alkyl [(Ci-C 8) - alkyl] amino- (Ci-C8) -alkoxycarbonyl , Cyano- (C 1 -C 8) -alkoxycarbonyl, heterocyclyl-N- (C 1 -C 8) -alkoxycarbonyl, heteroaryloxycarbonyl,
Heteroaryl-(d-C8)-alkoxycarbonyl, Heterocyclyl-(Ci-C8)-alkoxycarbonyl, Heterocyclyloxycarbonyl, (C2-C8)-Alkenyl-(Ci-C8)-alkoxycarbonyl, (C2-C8)-Alkinyl-(Ci-C8)-alkoxycarbonyl, Aryl-(C2-C8)-alkinyloxycarbonyl, Aryl-(C2-C8)-alkenyloxycarbonyl, Aminocarbonyl, (Ci-Cs)- Alkylaminocarbonyl, Bis[(CrC8)-alkyl]aminocarbonyl, (d-Cs)- Alkyl[(Ci-C8)-Alkyl]aminocarbonyl, (Ci-C8)-Alkyl[(Ci-C8)- Alkoxy]aminocarbonyl, (C2-C8)-Alkenylaminocarbonyl, (Ca-Cs)- Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-Ce)- alkylaminocarbonyl, Heteroaryl-(CrC8)-alkylaminocarbonyl, Cyano- (Ci-C8)-alkylaminocarbonyl, (Ci-C8)-Haloalkylaminocarbonyl, (Cz-Cs)- Alkinyl-(Ci-C8)-alkylaminocarbonyl, (Ci-Cs)-Heteroaryl- (C 1 -C 8) -alkoxycarbonyl, heterocyclyl- (C 1 -C 8) -alkoxycarbonyl, heterocyclyloxycarbonyl, (C 2 -C 8) -alkenyl- (C 1 -C 8) -alkoxycarbonyl, (C 2 -C 8) -alkynyl- (C 1 -C 8) -cycloxycarbonyl; ) -alkoxycarbonyl, aryl- (C 2 -C 8) -alkynyloxycarbonyl, aryl- (C 2 -C 8) -alkenyloxycarbonyl, aminocarbonyl, (C 1 -C 8) -alkylaminocarbonyl, bis [(C 1 -C 8) -alkyl] -aminocarbonyl, (C 1 -C 5) - alkyl [(Ci-C 8) alkyl] aminocarbonyl, (Ci-C 8) alkyl [(Ci-C 8) - alkoxy] aminocarbonyl, (C2-C8) -Alkenylaminocarbonyl, (Ca-Cs) - cycloalkylaminocarbonyl, arylaminocarbonyl , Aryl- (C 1 -C 6) -alkylaminocarbonyl, heteroaryl- (C 1 -C 8) -alkylaminocarbonyl, cyano- (Ci-C8) -alkylaminocarbonyl, (Ci-C8) -haloalkylaminocarbonyl, (Cz-Cs) - alkynyl- (Ci-C8) -alkylaminocarbonyl, (Ci-Cs) -
Alkoxycarbonylaminocarbonyl, Aryl-(Ci-Ce)- alkoxycarbonylaminocarbonyl, Hydroxycarbonyl-(Ci-Ce)-alkyl, (CrCs)- Alkoxycarbonyl-(d-C8)-alkyl, (C3-C8)-Cycloalkoxycarbonyl-(d-C8)-alkyl, (C3-C8)-Cycloalkyl-(Ci-C8)-a!koxycarbonyl-(Ci-C8)-alkyl, (C2-C8)- Alkenyloxycarbonyl-(CrC8)-alkyl, Aryl-(Ci-Cs)-alkoxycarbonyl-(Ci-C8)- alkyl, (Ci-C8)-Alkylaminocarbonyl-(Ci-C8)-alkyl, Aminocarbonyl-(Ci-C8)- alkyl, Bis[(Ci-C8)-alkyl]aminocarbonyl-(Ci-C8)-alkyl, (C3-C8)- Cycloalkylaminocarbonyl-(Ci-C8)-alkyl, Aryl-(Ci-C8)-alkylaminocarbonyl- (Ci-C8)-alkyl, Heteroaryl-(Ci-C8)-alkylaminocarbonyl-(Ci-C8)-alkyl, Cyano-(Ci-C8)-alkylaminocarbonyl-(CrC8)-alkyl, (Ci-Cs)- Haloalkylaminocarbonyl-(Ci-C8)-alkyl, (C2-Ce)-Alkinyl-(Ci-C8)- alkylaminocarbonyl-(Ci-C8)-alkyl, (C3-Ce)-Cycloalkyl-(Ci-Ce)- alkylaminocarbonyl-(Ci-C8)-alkyl, (Ci-CsJ-Alkoxycarbonylaminocarbonyl- (d-C8)-alkyl, Aryl-(Ci-C8)-alkoxycarbonylaminocarbonyl-(Ci-C8)-alkyl, (Ci-C8)-Alkoxycarbonyl-(Ci-C8)-alkylaminocarbonyl, Hydroxycarbonyl- (Ci-C8)-alkylaminocarbonyl, Aryl-(Ci-C8)-alkoxycarbonyl-(Ci-C8)- alkylaminocarbonyl, Aminocarbonyl-(Ci-C8)-alkylaminocarbonyl, (Ci-Cs)- Alkylaminocarbonyl-(Ci-C8)-alkylaminocarbonyl. Alkoxycarbonylaminocarbonyl, aryl- (Ci-Ce) -alkoxycarbonylaminocarbonyl, hydroxycarbonyl- (Ci-Ce) -alkyl, (CrCs) -alkoxycarbonyl- (d-C8) -alkyl, (C3-C8) -cycloalkoxycarbonyl- (d-C8) - alkyl, (C3-C8) -cycloalkyl- (Ci-C8) -a koxycarbonyl- (Ci-C 8) alkyl, (C 2 -C 8) - alkenyloxycarbonyl (CRC8) alkyl, aryl (Ci- Cs) -alkoxycarbonyl- (C 1 -C 8 ) -alkyl, (C 1 -C 8 ) -alkylaminocarbonyl- (C 1 -C 8 ) -alkyl, aminocarbonyl- (C 1 -C 8 ) -alkyl, bis [(C 1 -C 8 ) -alkyl] aminocarbonyl- (C 1 -C 8 ) -alkyl, (C 3 -C 8 ) -cycloalkylaminocarbonyl- (C 1 -C 8 ) -alkyl, aryl- (C 1 -C 8 ) -alkylaminocarbonyl- (C 1 -C 8 ) -alkyl, heteroaryl- (Ci -C 8 ) -alkylaminocarbonyl- (C 1 -C 8 ) -alkyl, cyano- (C 1 -C 8 ) -alkylaminocarbonyl- (C 1 -C 8 ) -alkyl, (C 1 -C 8 ) -haloalkylaminocarbonyl- (C 1 -C 8 ) -alkyl, (C 2 -C 8 ) -alkyl) Ce) -alkynyl- (C 1 -C 8 ) -alkylaminocarbonyl- (C 1 -C 8 ) -alkyl, (C 3 -C 6) -cycloalkyl- (C 1 -C 6) -alkylaminocarbonyl- (C 1 -C 8 ) -alkyl, (C 1 -C -J Alkoxycarbonylaminocarbonyl- (C 1 -C 8 ) -alkyl, aryl- (C 1 -C 8 ) -alkoxycarbonylaminocarbonyl- (C 1 -C 8 ) -alkyl, (C 1 -C 8 ) -alkoxycarbonyl- (C 1 -C 8 ) -alkylaminocarbonyl, hydroxycarbo nyl- (C 1 -C 8 ) -alkylaminocarbonyl, aryl- (C 1 -C 8 ) -alkoxycarbonyl- (C 1 -C 8 ) -alkylaminocarbonyl, aminocarbonyl- (C 1 -C 8 ) -alkylaminocarbonyl, (C 1 -C 8 ) -alkylaminocarbonyl- (C 1 -C 4) -alkylaminocarbonyl C8) alkylaminocarbonyl.
(C3-C8)-Cycloalkylaminocarbonyl-(Ci-C8)-alkylaminocarbonyl, (Ca-Ce)- Cycloalkyl-(Ci-C8)-alkylaminocarbonyl, (C3-C8)-Cycloalkyl-(Ci-C8)- alkylaminocarbonyl-(Ci-C8)-alky!, (C3-C8)-Cycloalky!-(CrC8)- alkylaminocarbonyl-(Ci-C8)-alky!aminocarbonyl, (C2-C8)-Alkenyl-(Ci-C8)- alkylaminocarbonyl, (C2-C8)-Alkenylaminocarbonyl-(Ci-C8)-alkyl, (C2-C-8)- Alkenyl-(Ci-C8)-alkylaminocarbonyl-(Ci-C8)-alkyl, (Ci-Cs)-Alkylcarbonyl, (C3-C8)-Cycloalkylcarbonyl, Arylcarbonyl, Formyl, Hydroxyiminomethyl, Aminoiminomethyl, (Ci-C8)-Alkoxyiminomethyl, (Ci-Cs)- Alkylaminoiminomethyl, Bis[(Ci-C8)-alkyl]aminoiminomethyl, (C3-Cs)- Cycloalkoxyiminomethyl, (C3-C8)-Cycloalkyl-(Ci-C8)-alkoximinomethyl, Aryloximinomethyl, Aryl-(Ci-C8)-alkoxyiminomethyl, Aryl-(Ci-Cs)- alkylaminoiminomethyl, (C2-C8)-Alkenyloxyiminomethyl, (C 3 -C 8) -cycloalkylaminocarbonyl- (C 1 -C 8) -alkylaminocarbonyl, (Ca-Ce) -cycloalkyl- (C 1 -C 8) -alkylaminocarbonyl, (C 3 -C 8) -cycloalkyl- (C 1 -C 8) -alkylaminocarbonyl- (Ci -C 8) -alky !, (C3-C8) -Cycloalky - (CrC 8) - alkylaminocarbonyl (Ci-C8) -alky aminocarbonyl, (C2-C8) alkenyl (Ci-C8) - alkylaminocarbonyl , (C 2 -C 8 ) -alkenylaminocarbonyl- (C 1 -C 8 ) -alkyl, (C 2 -C 8 ) -alkenyl- (C 1 -C 8 ) -alkylaminocarbonyl- (C 1 -C 8 ) -alkyl, (C 1 -C 8 ) -alkyl, Alkylcarbonyl, (C 3 -C 8 ) -cycloalkylcarbonyl, arylcarbonyl, formyl, hydroxyiminomethyl, aminoiminomethyl, (C 1 -C 8 ) -alkoxyiminomethyl, (C 1 -C 8 ) -alkylaminoiminomethyl, bis [(C 1 -C 8 ) -alkyl] aminoiminomethyl, (C 3 -Cs) - cycloalkoxyiminomethyl, (C 3 -C 8) -cycloalkyl- (C 1 -C 8) -alkoximinomethyl, aryloximinomethyl, aryl- (C 1 -C 8) -alkoxyiminomethyl, aryl- (C 1 -C 8) -alkylaminoiminomethyl, (C 2 -C 8) -Alkenyloxyiminomethyl,
Arylaminoiminomethyl, Arylsulfonylaminoiminomethyl, Heteroaryl-(Ci-C8)- alkyl, Heterocyclyl-(Ci-C8)-alkyl, Hydroxycarbonylheterocyclyl, (Ci-Cs)- Alkoxycarbonylheterocyclyl, (C2-C8)-Alkenyloxycarbonylheierocyclyl, (C2-C8)-Alkenyl-(CrC8)-alkoxycarbonylheterocyclyl, Aryl-(Ci-Ce)- alkoxycarbonylheterocyclyl, (Ca-CeJ-Cycloalkoxycarbonylheterocyclyl, (C3-C8)-Cycloalkyl-(CrC8)-alkoxycarbonylheterocyclyL Arylaminoiminomethyl, arylsulfonylaminoiminomethyl, heteroaryl- (C 1 -C 8 ) -alkyl, heterocyclyl- (C 1 -C 8 ) -alkyl, hydroxycarbonylheterocyclyl, (C 1 -C 8) - Alkoxycarbonylheterocyclyl, (C 2 -C 8) -alkenyloxycarbonylheierocyclyl, (C 2 -C 8) -alkenyl- (C 1 -C 8) -alkoxycarbonyl-heterocyclyl, aryl- (C 1 -C 6) -alkoxycarbonyl-heterocyclyl, (C 1 -C 12 -cycloalkoxycarbonyl-heterocyclyl, (C 3 -C 8) -cycloalkyl- CRC8) -alkoxycarbonylheterocyclyL
Aminocarbonylheterocyclyl, (Ci-C8)-Alkylaminocarbonylheterocyclyl, Bis[(Ci-C8)-Alkyl]aminocarbonylheterocyclyl, (Ca-Ce)- Cycloalkylaminocarbonylheterocyclyl, Aryl-(Ci-Cs)- alkylaminocarbonylheterocyclyl, (C2-C8)- Aminocarbonylheterocyclyl, (Ci-C8) -alkylaminocarbonylheterocyclyl, bis [(Ci-C8) -alkyl] aminocarbonylheterocyclyl, (Ca-Ce) - cycloalkylaminocarbonylheterocyclyl, aryl- (Ci-Cs) - alkylaminocarbonylheterocyclyl, (C2-C8) -
Alkenylaminocarbonylheterocyclyl, Hydroxycarbonylheterocyclyl-(Ci-C8)- alkyl, (Ci-C8)-Alkoxycarbonylheterocyclyl-(Ci-C8)-alkyl, Hydroxycarbonyl-Alkenylaminocarbonylheterocyclyl, hydroxycarbonylheterocyclyl- (C 1 -C 8) -alkyl, (C 1 -C 8) -alkoxycarbonylheterocyclyl- (C 1 -C 8) -alkyl, hydroxycarbonyl-
(C3-C8)-cycloalkyi-(Ci-C8)-alkyl, (Ci-C8)-Alkoxycarbonyl-(C3-C8)- cycloalkyl-(Ci-C8)-alkyL Hydroxyaminocarbonyl, (Ci-Ce)- Alkoxyaminocarbonyl, Aryl-(Ci-C8)-alkoxyaminocarbonyl, Heterocyclyl, (d-C8)-Alkylcarbonyloxy, Arylcarbonyloxy, Heteroarylcarbonyloxy, (C 3 -C 8) -cycloalkyi- (Ci-C 8) alkyl, (Ci-C8) alkoxycarbonyl (C3-C8) - cycloalkyl- (Ci-C8) alkyl, hydroxyaminocarbonyl, (Ci-Ce) Alkoxyaminocarbonyl, aryl- (C 1 -C 8) -alkoxyaminocarbonyl, heterocyclyl, (C 1 -C 8) -alkylcarbonyloxy, arylcarbonyloxy, heteroarylcarbonyloxy,
(Ca-CeJ-Cycloalkylcarbonyloxy, (Ci-C8)-Alkoxycarbonyloxy, (C2-C8)- Alkenyloxycarbonyloxy, Aminosulfonyl, (Ci-C8)-Alkoxycarbonyl- heterocyclyl-N-carbonyl, (CrC8)-Alkoxycarbonyl-(Ci-C8)-alkyl- heterocyclylidenaminocarbonyl, (Ci-C8)-Alkoxycarbonylheterocyclyliden- (Ci-C8)-alkylaminocarbonyl (Ci-C8)-Alkoxycarbonyl-(Ci-C8)-Alkyl((Ci-C8)- alkyl)aminocarbonyl, (Ci-Cs)-Alkoxycarbonyl-(C3-Cs)- cycloalkylidenaminocarbonyl, Heterocyclyl-N-carbonyl, (CrCsJ-Alkoxy- (Ci-Cs)-alkylaminocarbonyl sieht, (C 1 -C 12 -cycloalkylcarbonyloxy, (C 1 -C 8) -alkoxycarbonyloxy, (C 2 -C 8) -alkenyloxycarbonyloxy, aminosulfonyl, (C 1 -C 8) -alkoxycarbonyl-heterocyclyl-N-carbonyl, (C 1 -C 8) -alkoxycarbonyl- (C 1 -C 8) alkyl heterocyclylidenaminocarbonyl, (Ci-C8) -Alkoxycarbonylheterocyclyliden- (Ci-C8) alkylaminocarbonyl (Ci-C8) alkoxycarbonyl (Ci-C 8) alkyl ((Ci-C 8) - alkyl) aminocarbonyl, ( Ci-Cs) -alkoxycarbonyl- (C3-Cs) - cycloalkylidenaminocarbonyl, heterocyclyl-N-carbonyl, (CrCsJ-alkoxy- (Ci-Cs) -alkylaminocarbonyl sees,
R7, R8, R9, R10, R11 und R12 unabhängig voneinander für Wasserstoff, (Ci-C8)- Alkyl, (C3-C8)-Cycloalkyl, (C2-C8)-Alkenyl, (C2-C8)-Alkenyl-(Ci-C8)-alkyl, (Ci-C8)-Alkoxy-(Ci-C8)-alkyl, Hydroxy-(CrC8)-alkyi, (Ci-C8)-Haloalkyl, (C2-C8)-Haloalkenyl, (Ci-C8)-Haloalkoxy-(Ci-Cs)-alkyl, (Ci-C8)-Alkoxy- (Ci-C8)-haloalkyl, (Ci-C8)-Ha!oalkoxy-(Ci-C8)-haloalkyl, (Ci-Cs)-Alkoxy, (Ci-C8)-Alkylthio, (Ci-C8)-Alkylamino, Halogen, Amino stehen, wobei mindestens eine der Gruppen R7, R8, R9, R10, R1 1 und R12 nicht für Wasserstoff steht und R 7, R 8, R 9, R 10, R 11 and R 12 are independently hydrogen, (Ci-C 8) - alkyl, (C 3 -C 8) cycloalkyl, (C 2 -C 8) alkenyl , (C 2 -C 8 ) -alkenyl- (C 1 -C 8 ) -alkyl, (C 1 -C 8 ) -alkoxy- (C 1 -C 8 ) -alkyl, hydroxy- (C 1 -C 8 ) -alkyl, (C 1 -C 8 ) -alkyl) 8) -haloalkyl, (C 2 -C 8) -haloalkenyl, (Ci-C8) haloalkoxy (Ci-Cs) alkyl, (Ci-C 8) alkoxy (Ci-C 8) haloalkyl, (C 1 -C 8 ) -haloalkoxy- (C 1 -C 8 ) -haloalkyl, (C 1 -C 5) -alkoxy, (C 1 -C 8 ) -alkylthio, (C 1 -C 8 ) -alkylamino, halogen, amino wherein at least one of the groups R 7, R 8, R 9, R 10, R 1 1 and R 12 is not hydrogen, and
R3 und R4 mit dem Atom, an das sie gebunden sind, eine exo-Alkylidengruppe oder einen vollständig gesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 6-gliedrigen Ring bilden, R 3 and R 4 with the atom to which they are attached, an exo-alkylidene group or a fully saturated, optionally O (oxygen), S (sulfur) or a group NH, NR 37 form interrupted and optionally further substituted 3 to 6-membered ring,
R1 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig R 1 and R 11 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, form a saturated or partially saturated 5 to 7-membered ring, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted,
R1 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig R 1 and R 9 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, form a saturated or partially saturated 3 to 7-membered ring, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted,
R3 und R7 mit den Atomen, an die sie gebunden sind, einen vollständig R 3 and R 7 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, form a saturated or partially saturated 5 to 7-membered ring, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted,
R3 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig R 3 and R 11 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, form a saturated or partially saturated 3 to 7-membered ring, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted,
R1 und R3 mit den Atomen, an die sie gebunden sind, einen vollständig R 1 and R 3 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, form a saturated or partially saturated 5 to 7-membered ring, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted,
R7 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig R 7 and R 11 complete with the atoms to which they are attached
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R3 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, form a saturated or partially saturated 5 to 7-membered ring, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted, R 3 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
R7 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig R 7 and R 9 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, form a saturated or partially saturated 3 to 7-membered ring, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted,
R13, R14, R15 und R16 unabhängig voneinander für Wasserstoff, Halogen, Nitro, Amino, Cyano, (d-C8)-Alkyl, Aryl, Heteroaryl, (C3-C-8)-Cycloalkyl, (C4-C8)- Cycloalkenyl, (C2-C8)-Alkenyl, (C2-C8)-Alkinyl, (C2-C8)-Alkenyl-(Ci-C8)- alkyl, (C2-C8)-Alkinyl-(Ci-C8)-alkyl, Hydroxy, (d-C8)-Alkoxy, (d-Ce)- Alkoxy-(Ci-C8)-alkoxy, (Ci-C8)-Alkoxy-(CrC8)-alkyl, Hydroxy-(Ci-C8)- alkyl, (d-C8)-Haloalkoxy, (Ci-C8)-Haloalkyl, (C2-C8)-Haloalkenyl, (C2-C8)- Haloalkinyl, (Ci-C8)-Haloalkoxy-(CrC8)-alkyl, (Ci-C8)-Alkoxy-(Ci-C8)- haloalkyl, (Ci-C8)-Haloalkoxy-(Ci-C8)-haloalkyl, Hydrothio, (Ci-C8)- Alkylthio, (Ci-Cs)-Haloalkylthio, (Ci-C8)-Alkylthio-(Ci-C8)-alkyl, (Ci-Ce)- Haloalkylthio-(Ci-C8)-alkyl, (Ci-C8)-Alkylamino, Bis-[(Ci-C8)-alkyl]amino, (C2-C8)-Alkenylamino, (C3-C8)-Cycloalkylamino, (Ci-C8)- Alkylcarbonylamino, (C3-C8)-Cycloalkylcarbonylamino, R 13 , R 14 , R 15 and R 16 independently of one another represent hydrogen, halogen, nitro, amino, cyano, (C 1 -C 8 ) -alkyl, aryl, heteroaryl, (C 3 -C 8) -cycloalkyl, (C 4 -C 8) - cycloalkenyl, (C 2 -C 8) alkenyl, (C 2 -C 8) -alkynyl, (C 2 -C 8) alkenyl (Ci-C 8) - alkyl, (C 2 -C 8 ) alkynyl (Ci-C 8) alkyl, hydroxy, (dC 8) -alkoxy, (d-Ce) - alkoxy- (Ci-C 8) alkoxy, (Ci-C 8) alkoxy (CrC 8) alkyl, hydroxy (Ci-C 8) - alkyl, (dC 8) -haloalkoxy, (Ci-C 8) haloalkyl, (C 2 -C 8) -haloalkenyl, (C 2 -C 8) - Haloalkynyl, (C 1 -C 8 ) -haloalkoxy- (C 1 -C 8 ) -alkyl, (C 1 -C 8 ) -alkoxy- (C 1 -C 8 ) -haloalkyl, (C 1 -C 8 ) -haloalkoxy- (C 1 -C 8 ) haloalkyl, Hydrothio, (Ci-C 8) - alkylthio, (Ci-Cs) haloalkylthio, (Ci-C8) alkylthio (Ci-C8) alkyl, (Ci-Ce) - Haloalkylthio- ( Ci-C 8) alkyl, (Ci-C 8) alkylamino, - bis [(Ci-C 8) alkyl] amino, (C2 -C8) -alkenylamino, (C3-C8) cycloalkylamino, (C 1 -C 8 ) -alkylcarbonylamino, (C 3 -C 8 ) -cycloalkylcarbonylamino,
Arylcarbonylamino, Heteroarylcarbonylamino, Formylamino, (Ci-C8)- Haloalkylcarbonylamino, (d-C8)-Alkoxycarbonylamino, (Ci-C8)- Alkylaminocarbonylamino, (Ci-C8)- Alkyl[(Ci-C8)- Alkyljaminocarbonylamino, (CrC8)-Alkylsulfonylamino, (C3-C8)- Cycloalkylsulfonylamino, Arylsulfonylamino, Hetarylsulfonylamino, Sulfonyl-(Ci-C8)-haloalkylamino, Amino-(Ci-C8)-alkylsulfonyl, Amino- (Ci-C8)-haloalkylsulfonyl, (Ci-C8)-Alkylaminosulfonyl, Bis[(Ci-Ce)- alkyl]aminosulfonyl, (C3-C8)-Cycloalkylaminosulfonyl, (Ci-C8)- Haloalkylaminosulfonyl, Heteroarylaminosulfonyl, Arylaminosuifonyl, Aryl- (CrC8)-alkylaminosulfonyl, (d-C8)-Alkylsulfonyl, (C3-C8)- Cycloalkylsulfonyl, Arylsulfonyl, Hydroxycarbonyl, (Ci-C8)- Alkoxycarbonyl, (C3-C8)-Cycloalkoxycarbonyl, (C3-C8)-Cycloalkyl-(d-C8)- alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C-8)-alkoxycarbonyl, (Cz-Cs)- Alkenyloxycarbonyl, (C2-C8)-Alkinyloxycarbonyl, Aminocarbonyl, (Ci-C8)- Alkylaminocarbonyl, Bis[(CrC8)-alkyl]aminocarbonyl, (CrC8)- Alkyl[(Ci-C8)-Alkyl]aminocarbonyl, (Ci-C8)-Alkyl[(Ci-C8)- Alkoxyjaminocarbonyl, (C2-C8)-Alkenylaminocarbonyl, (Ca-Ce)- Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(d-C8)- alkylaminocarbonyl stehen, Arylcarbonylamino, heteroarylcarbonylamino, formylamino, (Ci-C 8) - Haloalkylcarbonylamino, (DC 8) alkoxycarbonylamino, (Ci-C 8) - alkylaminocarbonylamino, (Ci-C 8) - alkyl [(Ci-C 8) - Alkyljaminocarbonylamino, ( -C 8) alkylsulfonylamino, (C3-C8) - cycloalkylsulfonylamino, arylsulfonylamino, Hetarylsulfonylamino, sulfonyl (Ci-C (8) -haloalkylamino, amino Ci-C 8) alkylsulfonyl, amino (Ci-C8) - haloalkylsulfonyl, (C 1 -C 8 ) -alkylaminosulfonyl, bis [(C 1 -C 6 ) -alkyl] -aminosulfonyl, (C 3 -C 8 ) -cycloalkylaminosulfonyl, (C 1 -C 8 ) -haloalkylaminosulfonyl, heteroarylaminosulfonyl, arylaminosulfonyl, aryl- (CrC 8 ) alkylaminosulfonyl, (dC 8) alkylsulfonyl, (C 3 -C 8) - cycloalkylsulfonyl, arylsulfonyl, hydroxycarbonyl, (Ci-C8) - alkoxycarbonyl, (C3-C8) -cycloalkoxycarbonyl, (C3-C8) - Cycloalkyl- (dC 8 ) - alkoxycarbonyl, aryloxycarbonyl, aryl (Ci-C8) -alkoxycarbonyl, (Cz-Cs) - alkenyloxycarbonyl, (C2-C8) -alkynyloxycarbonyl, aminocarbonyl, (Ci-C8) - alkylaminocarbonyl, bis [(CRC8) alkyl ] aminocarbonyl, (CrC 8) - alkyl [(Ci-C 8) alkyl] aminocarbonyl, (Ci-C 8) alkyl [(Ci-C 8) - Alkoxyjaminocarbonyl, (C2-C8) -Alkenylaminocarbonyl, (Ca Ce) - cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 8) -alkylaminocarbonyl,
A1 , A2, A3 und A4 gleich oder verschieden sind und unabhängig voneinander für N (Stickstoff) oder die Gruppierungen C-H, C-CH3, C-F, C-Cl, C-Br, C-l, C-OCFa, C-OCH3, C-CF3, C-CO2H, C-CO2CH3 stehen, wobei jedoch in keinem Fall mehr als zwei -Atome benachbart sind, A 1 , A 2 , A 3 and A 4 are the same or different and are independently N (nitrogen) or the groupings CH, C-CH 3 , CF, C-Cl, C-Br, Cl, C-OCFa, C -OCH3, C-CF3, C-CO2H, C-CO2CH3, but in no case more than two atoms are adjacent,
R17 und R18 unabhängig voneinander für Wasserstoff, Halogen, (Ci-Cs)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (C3-C8)-Cycloalkyl, (C2-Cs)-Alkenyl, (C2-C8)-Alkinyl, (CrC8)-Alkoxy, (Ci-C8)-Alkoxy-(Ci-C8)-alkyl, Aryloxy- (Ci-C8)-alkyl, (Ci-C8)-Haloalkoxy, (CrC8)-Haloalkyl, (Ci-Cs)-Haloalkoxy- (Ci-C8)-alkyl, (Ci-C8)-Alkoxy-(Ci-C8)-haloalkyl, (Ci-C8)-Haloalkoxy- (Ci-C8)-haloalkyl, (Ci-Cs)-Alkylthio, (Ci-C8)-Haloalkylthio, (Ci-Ce)- Alkylthio-(Ci-C8)-alkyl, Hydroxycarbonyl, (Ci-C8)-Alkoxycarbonyl, (Cs-Ce)- Cycloalkoxycarbonyl, (C3-C8)-Cycloalkyl-(CrC8)-alkoxycarbonyl, R 17 and R 18 independently of one another are hydrogen, halogen, (C 1 -C 5 ) -alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 8 ) -cycloalkyl, (C 2 -C 5 ) -alkenyl, (C 2 -C 8 ) - Alkynyl, (C 1 -C 8 ) -alkoxy, (C 1 -C 8 ) -alkoxy- (C 1 -C 8 ) -alkyl, aryloxy- (C 1 -C 8 ) -alkyl, (C 1 -C 8 ) -haloalkoxy, (CrC 8 ) -haloalkyl, (Ci-Cs) haloalkoxy (Ci-C 8) alkyl, (Ci-C 8) alkoxy (Ci-C 8) haloalkyl, (Ci-C8) haloalkoxy (C -C 8) -haloalkyl, (Ci-Cs) -alkylthio, (Ci-C8) haloalkylthio, (Ci-Ce) - alkylthio (Ci-C8) alkyl, hydroxycarbonyl, (Ci-C8) alkoxycarbonyl, (Cs-Ce) - cycloalkoxycarbonyl, (C 3 -C 8) -cycloalkyl- (C 1 -C 8) -alkoxycarbonyl,
Aryloxycarbonyl, Aryl-(Ci-C8)-alkoxycarbonyl, (C2-C8)- Alkenyloxycarbonyl, (C2-C8)-Alkinyloxycarbonyl, Aminocarbonyl, (Ci-C8)- Alkylaminocarbonyl, Bis[(Ci-C8)-alkyl]aminocarbonyl, (d-Cs)- Alkyl[(Ci-C8)-Alkyl]aminocarbonyl, (Ci-C8)-Alkyl[(Ci-C8)- Alkoxy]aminocarbonyl, (C2-C8)-Alkenylaminocarbonyl, (C3-C8)- Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-Cs)- alkylaminocarbonyl stehen, Aryloxycarbonyl, aryl (Ci-C8) -alkoxycarbonyl, (C2-C8) - alkenyloxycarbonyl, (C2-C8) -alkynyloxycarbonyl, aminocarbonyl, (Ci-C8) - alkylaminocarbonyl, bis [(Ci-C 8) alkyl] aminocarbonyl, (C 1 -C 5 ) -alkyl [(C 1 -C 8 ) -alkyl] aminocarbonyl, (C 1 -C 8 ) -alkyl [(C 1 -C 8 ) -alkoxy] aminocarbonyl, (C 2 -C 8 ) -Alkenylaminocarbonyl, (C3-C8) - cycloalkylaminocarbonyl, arylaminocarbonyl, aryl (Ci-Cs) - are alkylaminocarbonyl,
A5 für S (Schwefel), O (Sauerstoff) oder die Gruppierungen N-H, N-CH3, N- CH2CH3, N-CH(CH3)2, N-C02t-Bu, N-Aryl, N-Heteroaryl, N-Heterocyclyl steht, R19, R20, R23 und R24 unabhängig voneinander für Wasserstoff, (Ci-Cs)-Alkyl, Halogen, (C3-C8)-Cycioalkyl, Aryl, Heteroaryl, Heterocyclyl, (C2-C-8)- Alkenyi, (C2-C8)-Alkenyl-(Ci-C8)-alkyl, Aryl-(Ci-C8)-alkyl, (CrC8)-Alkoxy, (Ci-C8)-Alkoxy-(d-C8)-alkoxy, (Ci-C8)-Alkoxy-(Ci-C8)-alkyl, Hydroxy, (d-C8)-Haloalkyl, (Ci-C8)-Haloaikyithio stehen, A 5 represents S (sulfur), O (oxygen) or the groupings NH, N-CH 3 , N-CH 2 CH 3 , N-CH (CH 3 ) 2 , N-CO 2 t-Bu, N-aryl, N-heteroaryl, N-heterocyclyl is R 19 , R 20 , R 23 and R 24 independently of one another represent hydrogen, (C 1 -C 5) -alkyl, halogen, (C 3 -C 8) -cycloalkyl, aryl, heteroaryl, heterocyclyl, (C 2 -C 8) -alkenyl, (C 2 -C 8 ) -alkenyl- (C 1 -C 8 ) -alkyl, aryl- (C 1 -C 8 ) -alkyl, (C 1 -C 8 ) -alkoxy, (C 1 -C 8 ) -alkoxy- (C 1 -C 8 ) - alkoxy, (C 1 -C 8 ) -alkoxy- (C 1 -C 8 ) -alkyl, hydroxy, (C 1 -C 8 ) -haloalkyl, (C 1 -C 8 ) -haloalkylthio,
R19 und R23 mit den Atomen, an die sie gebunden sind, einen vollständig R 19 and R 23 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden,  form a saturated or partially saturated, optionally further substituted 5 to 7-membered ring,
A6, A7 gleich oder verschieden sind und unabhängig voneinander für O A 6 , A 7 are the same or different and are each independently O.
(Sauerstoff), S (Schwefel), N-H, N-OCH3, N-CH3 oder die Gruppierung CR21R22 stehen, wobei jedoch in keinem Fall zwei N-, O- oder S-Atome benachbart sind, und wobei R21 und R22 in der Gruppierung CR21 R22 jeweils gleiche oder verschiedene Bedeutungen gemäß der (Oxygen), S (sulfur), NH, N-OCH 3 , N-CH 3 or the group CR 21 R 22 are, but in any case, two N, O or S atoms are adjacent, and wherein R 21 and R 22 in the group CR 21 R 22 each have the same or different meanings according to the
nachstehenden Definition haben und  have the following definition and
R21 und R22 unabhängig voneinander für Wasserstoff, Halogen, (d-Cs)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (C3-C8)-Cycloalkyl, (C2-C8)-Alkenyl, (Ci-Cs)-Alkoxy, (Ci-C8)-Alkoxy-(Ci-C8)-alkyl, Aryloxy-(Ci-C8)-alkyl, (d-C8)-Haloalkoxy, (d-C8)-Haloalkyl, (Ci-C8)-Haloalkoxy-(Ci-C8)-alkyl, (Ci-C8)-Alkoxy-(CrC8)-haloalkyl, (Ci-C8)-Haloalkoxy-(CrC8)-haloalkyl, (d-C8)-Alkylthio, (d-C8)-Haloalkylthio, (Ci-C8)-Alkylthio-(Ci-C8)-alkyl, Hydroxycarbonyl, (Ci-C8)-Alkoxycarbonyl , (C;rC8)-Cycloalkoxycarbonyl, (C3-C8)-Cycloalkyl-(CrC8)-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C8)- alkoxycarbonyl , (C2-C8)-Alkenyloxycarbonyl , (C2-C8)-Al ki nyloxycarbonyl , Aminocarbonyl, (Ci-C8)-Alkylaminocarbonyl, Bis[(Ci-C8)- alkyljaminocarbonyl, (Ci-C8)-Alkyl[(Ci-C8)-Alkyl]aminocarbonyl, (Ci-C8)- Alkyl[(Ci-C8)-Alkoxy]aminocarbonyl, (C2-C8)-Alkenylaminocarbonyl, (C3-C8)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(d-C8)- alkylaminocarbonyl, Amino, (CrC8)-Alkylamino, (C3-C8)-Cycloalkylamino, Bis-[(Ci-C8)-Alkyl]amino stehen, R25, R26, R28 und R29 unabhängig voneinander für Wasserstoff, (Ci-Cs)-Alkyl, Halogen, (C3-C8)-Cycioalkyl, Aryl, Heteroaryl, Heterocyciyi, (C2-C-8)- Alkenyl, Aryl-(d-C8)-alkyl, (Ci-C8)-Alkoxy, (Ci-C8)-Alkoxy-(Ci-C8)-alkoxy,R 21 and R 22 independently of one another represent hydrogen, halogen, (C 1 -C 5) -alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 8 ) -cycloalkyl, (C 2 -C 8 ) -alkenyl, (C 1 -C 5) - alkoxy, (Ci-C 8) alkoxy (Ci-C 8) alkyl, aryloxy (Ci-C8) alkyl, (dC 8) -haloalkoxy, (dC 8) -haloalkyl, (Ci-C 8 ) haloalkoxy (Ci-C 8) alkyl, (Ci-C 8) alkoxy (CrC 8) -haloalkyl, (Ci-C8) haloalkoxy (-C 8) -haloalkyl, (dC 8) - alkylthio, (dC 8) haloalkylthio, (Ci-C8) alkylthio (Ci-C8) alkyl, hydroxycarbonyl, (Ci-C8) alkoxycarbonyl, (C; rC 8) -cycloalkoxycarbonyl, (C3 C8) cycloalkyl (CrC 8) -alkoxycarbonyl, aryloxycarbonyl, aryl (Ci-C8) - alkoxycarbonyl, (C2-C8) alkenyloxycarbonyl, (C2-C8) -alkyl ki nyloxycarbonyl, aminocarbonyl, (C -C 8) alkylaminocarbonyl, bis [(Ci-C 8) - alkyljaminocarbonyl, (Ci-C 8) alkyl [(Ci-C 8) alkyl] aminocarbonyl, (Ci-C 8) - alkyl [(Ci- C 8 ) -alkoxy] aminocarbonyl, (C 2 -C 8 ) -alkenylaminocarbonyl, (C 3 -C 8 ) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 8 ) -alkylaminocarbonyl, amino, (C 1 -C 8 ) -alkylamino, (C 3 -C 8 ) -cycloalkylamino, bis - [(C 1 -C 8 ) -alkyl] -amino, R 25 , R 26 , R 28 and R 29 independently of one another represent hydrogen, (C 1 -C 5) -alkyl, halogen, (C 3 -C 8) -cycloalkyl, aryl, heteroaryl, heterocyclic, (C 2 -C 8) -alkenyl, Aryl- (C 1 -C 8 ) -alkyl, (C 1 -C 8 ) -alkoxy, (C 1 -C 8 ) -alkoxy- (C 1 -C 8 ) -alkoxy,
(Ci-C8)-Alkoxy-(Ci-C8)-alkyl, (d-C8)-Haloalkyl stehen, (C 1 -C 8 ) -alkoxy- (C 1 -C 8 ) -alkyl, (C 1 -C 8 ) -haloalkyl,
A8 für O (Sauerstoff), S (Schwefel), N-H, N-CH3, N-OCH3 oder die Gruppierung CHR27 steht und wobei R27 in der Gruppierung CHR27 die Bedeutung gemäß der nachstehenden Definition hat, A 8 is O (oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the moiety CHR 27 , and wherein R 27 in the moiety CHR 27 has the meaning as defined below,
R27 für Wasserstoff, Halogen, (Ci-C8)-Alkyl, Aryl, Heteroaryl, Heterocyciyi, R 27 represents hydrogen, halogen, (C 1 -C 8 ) -alkyl, aryl, heteroaryl, heterocyclic,
(C3-C8)-Cycloalkyl, (C2-C8)-Alkenyl, (d-C8)-Alkoxy, (Ci-C8)-Alkoxy- (Ci-Cs)-alkyl, Aryloxy-(Ci-C8)-alkyl, (d-C8)-Haloalkoxy, (Ci-C8)-Haloalkyl, (Ci-C8)-Alkoxy-(Ci-C8)-haloalkyl, (Ci-C8)-Haloalkoxy-(CrC8)-haloalkyl, (d-C8)-Alkylthio, (Ci-C8)-Haloalkylthio, (Ci-C8)-Alkylthio-(CrC8)-alkyl, Hydroxycarbonyl, (Ci-C8)-Alkoxycarbonyl, (C: C8)-Cycloalkoxycarbonyl, Aryl-(Ci-C8)-alkoxycarbonyl, (C2-C8)-Alkenyloxycarbonyl, (C2-C8)- Alkinyloxycarbonyl, Aminocarbonyl, (CrC8)-Alkylaminocarbonyl, (C 3 -C 8) cycloalkyl, (C 2 -C 8) alkenyl, (DC 8) alkoxy, (Ci-C 8) alkoxy (Ci-Cs) alkyl, aryloxy (Ci-C 8 ) -alkyl, (C 1 -C 8 ) -haloalkoxy, (C 1 -C 8 ) -haloalkyl, (C 1 -C 8 ) -alkoxy- (C 1 -C 8 ) -haloalkyl, (C 1 -C 8 ) -haloalkoxy- (CrC 8) -haloalkyl, (dC 8) alkylthio, (Ci-C8) haloalkylthio, (Ci-C8) alkylthio (-C 8) -alkyl, hydroxycarbonyl, (Ci-C8) alkoxycarbonyl, (C : C 8) -cycloalkoxycarbonyl, aryl (Ci-C8) -alkoxycarbonyl, (C2-C8) alkenyloxycarbonyl, (C 2 -C 8) - alkynyloxycarbonyl, aminocarbonyl, (CrC 8) alkylaminocarbonyl,
Bis[(Ci-C8)-alkyl]aminocarbonyl, (Ci-C8)-Alkyl[(Ci-C8)- Alkyljaminocarbonyl, (Ci-C8)-Alkyl[(Ci-C8)-Alkoxy]aminocarbonyl, (C2-C8)-Alkenylaminocarbonyl, (C3-C8)-Cycloalkylaminocarbonyl, Bis [(Ci-C 8) alkyl] aminocarbonyl, (Ci-C 8) alkyl [(Ci-C 8) - Alkyljaminocarbonyl, (Ci-C 8) alkyl [(Ci-C 8) alkoxy] aminocarbonyl , (C 2 -C 8 ) -alkenylaminocarbonyl, (C 3 -C 8 ) -cycloalkylaminocarbonyl,
Arylaminocarbonyl, Aryl-(CrC8)-alkylaminocarbonyl, Amino, (d-C8)- Alkylamino, (C3-C8)-Cycloalkylamino, Bis-[(Ci-C8)-Alkyl]amino steht, Arylaminocarbonyl, aryl (CRC8) alkylaminocarbonyl, amino, (DC 8) - alkylamino, (C3-C8) cycloalkylamino, bis - [(Ci-C8) alkyl] amino is,
R30, R31 , R32, R34, R35 und R36 unabhängig voneinander für Wasserstoff, (Ci-C8)- Alkyl, Halogen, (C3-C8)-Cycloalkyl, Aryl, Heteroaryl, Heterocyciyi, (C2-C-8)- Alkenyl, (Ci-C8)-Alkoxy, (Ci-C8)-Alkoxy-(Ci-C8)-alkoxy, (d-C8)-Alkoxy- (Ci-C8)-alkyl, (Ci-C8)-Haloalkyl, (Ci-C8)-Alkylthio, (Ci-Ce)-Haloalkylthio stehen, R 30, R 31, R 32, R 34, R 35 and R 36 are independently hydrogen, (Ci-C 8) - alkyl, halogen, (C3-C8) cycloalkyl, aryl, heteroaryl, heterocyclyl, (C2 -C-8) - alkenyl, (C 1 -C 8 ) -alkoxy, (C 1 -C 8 ) -alkoxy- (C 1 -C 8 ) -alkoxy, (C 1 -C 8 ) -alkoxy- (C 1 -C 8 ) -alkyl , (Ci-C 8) haloalkyl, (Ci-C8) alkylthio, are (Ci-Ce) haloalkylthio,
A9 für O (Sauerstoff), S (Schwefel), N-H, N-CH3, N-OCH3 oder die Gruppierung CHR33 steht und wobei R33 in der Gruppierung CHR33 die Bedeutung gemäß der nachstehenden Definition hat und R33 für Wasserstoff, Halogen, (Ci-C8)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (C3-C8)-Cycloalkyl, (C2-C8)-Alkenyl, (Ci-Cs)-Alkoxy, (Ci-Ce)-Alkoxy- (d-C8)-alkyl, Aryloxy-(CrC8)-alkyl, (d-C8)-Haloalkoxy, (Ci-C8)-Haloalkyl, (CrC8)-Alkylthio, (Ci-C8)-Haloalkylthio, Hydroxycarbonyl, (d-C8)- Alkoxycarbonyl, (C3-C8)-Cycloalkoxycarbonyl, Aryl-(d-C8)- alkoxycarbonyl , (C2-C8)-Alkenyloxycarbonyl , (C2-C8)-Al ki nyloxycarbonyl , Aminocarbonyl, (Ci-C8)-Alkylaminocarbonyl, Bis[(d-C8)- alkyl]aminocarbonyl, (Ci-C8)-Alkyl[(Ci-C8)-Alkyl]aminocarbonyl, (Ci-C8)- Alkyl[(Ci-C8)-Alkoxy]aminocarbonyl, (C2-C8)-Alkenylaminocarbonyl, A 9 is O (oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the group CHR 33 , and wherein R 33 in the group CHR 33 has the meaning as defined below and R 33 is hydrogen, halogen, (Ci-C 8) alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 8) cycloalkyl, (C2-C8) alkenyl, (Ci-Cs) alkoxy, ( Ci-Ce) alkoxy (dC 8) alkyl, aryloxy- (CrC 8) alkyl, (dC 8) -haloalkoxy, (Ci-C 8) haloalkyl, (CrC 8) alkylthio, (Ci-C 8 ) -haloalkylthio, hydroxycarbonyl, (dC 8 ) -alkoxycarbonyl, (C 3 -C 8 ) -cycloalkoxycarbonyl, aryl- (dC 8 ) -alkoxycarbonyl, (C 2 -C 8 ) -alkenyloxycarbonyl, (C 2 -C 8 ) -alki nyloxycarbonyl, aminocarbonyl, (Ci-C 8) alkylaminocarbonyl, bis [(dC 8) - alkyl] aminocarbonyl, (Ci-C 8) alkyl [(Ci-C 8) alkyl] aminocarbonyl, (Ci-C 8) Alkyl [(C 1 -C 8 ) -alkoxy] aminocarbonyl, (C 2 -C 8 ) -alkenylaminocarbonyl,
(C3-C8)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C8)- alkylaminocarbonyl, Amino, (Ci-C8)-Alkylamino, (C3-C8)-Cycloalkylamino, Bis-[(Ci-C8)-Alkyl]amino steht, (C 3 -C 8 ) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 8 ) -alkylaminocarbonyl, amino, (C 1 -C 8 ) -alkylamino, (C 3 -C 8 ) -cycloalkylamino, bis - [(C 1 -C 8 ) Alkyl] amino,
R37 für (d-C8)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (C3-C8)-Cycloalkyl, (C2-C8)- Alkenyl, (Ci-C8)-Alkoxy, (Ci-C8)-Alkoxy-(CrC8)-alkyl. Aryloxy-(Ci-C8)- alkyl, (Ci-C8)-Alkoxycarbonyl, (C:i-C8)- Cycloalkoxycarbonyl, Aryl-(Ci-C8)- alkoxycarbonyl , (C2-C8)-Alkenyloxycarbonyl , (C2-C8)-Al ki nyloxycarbonyl , (Ci-C8)-Alkylcarbonyl, (C3-C8)-Cycloalkylcarbonyl, Arylcarbonyl, R 37 for (dC 8) alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 8) cycloalkyl, (C 2 -C 8) - alkenyl, (Ci-C 8) alkoxy, (Ci-C 8 ) Alkoxy (C 1 -C 8 ) alkyl. Aryloxy (Ci-C8) - alkyl, (Ci-C8) alkoxycarbonyl, (C: iC 8) - cycloalkoxycarbonyl, aryl (Ci-C8) - alkoxycarbonyl, (C2-C8) alkenyloxycarbonyl, ( C2-C8) -alkyl ki nyloxycarbonyl, (Ci-C 8) alkylcarbonyl, (C3-C8) cycloalkylcarbonyl, arylcarbonyl,
Heteroarylcarbonyl steht.  Heteroarylcarbonyl stands.
3. Verwendung gemäß Anspruch 1 , wobei in Formel (I) 3. Use according to claim 1, wherein in formula (I)
[X-Y] für die Gruppierungen [X-Y] for the groupings
[X-Y]1 und [X-Y!2 steht, [XY] 1 and [XY! 2 stands,
Q für die Gruppierungen Q-1 bis Q-6 Q for the groupings Q-1 to Q-6
steht, wobei R13, R14, R15, R16, R17, R18, R19, R20, R23, R24, R25, R26, R28, R29, R30, R31, R32, R34, R35 und R36 sowie A1 bis A9 jeweils die Bedeutung gemäß der nachstehenden Definitionen haben und wobei der Pfeil für eine Bindung zur jeweiligen Gruppierung C-R6 in der allgemeinen where R 13 , R 14 , R 15 , R 16 , R 17 , R 18 , R 19 , R 20 , R 23 , R 24 , R 25 , R 26 , R 28 , R 29 , R 30 , R 31 , R 32 , R 34 , R 35 and R 36, and A 1 to A 9 are each as defined below, and wherein the arrow for linking to the respective grouping is CR 6 in the general
Formel (I) steht, für (Ci-C7)-Alkyl, (C3-C7)-Cycloalkyl, (C4-C7)-Cycloalkenyl, (C2-C7)- Alkenyl, (C2-C7)-Alkinyl, (C2-C7)-Alkenyl-(Ci-C7)-alkyl, (C2-C7)-Alkinyl- (Ci-C7)-alkyl, (Ci-C7)-Alkoxy-(Ci-C7)-alkyl, Hydroxy-(d-C7)-alkyl, (C1-C7)- Haloalkyl, (C2-C7)-Haloalkenyl, (C2-C7)-Haloalkinyl, (d-C7)-Haloalkoxy- (d-C7)-alkyl, (Ci-C7)-Alkoxy-(Ci-C7)-haloalkyl, (d-C7)-Haloalkoxy- (Ci-C7)-haloalkyl, (Ci-C7)-Alkylthio-(C1-C7)-alkyl, (d-C7)-Haloalkylthio- (Ci-C7)-alkyl steht, Formula (I), for (Ci-C 7 ) -alkyl, (C 3 -C 7 ) -cycloalkyl, (C 4 -C 7 ) -cycloalkenyl, (C 2 -C 7 ) -alkenyl, (C 2 -C 7 ) alkynyl, (C 2 -C 7) alkenyl (Ci-C7) alkyl, (C 2 -C 7) alkynyl (Ci-C7) alkyl, (Ci-C7) alkoxy - (Ci-C7) alkyl, hydroxy (dC 7) alkyl, (C1-C7) - haloalkyl, (C 2 -C 7) haloalkenyl, (C 2 -C 7) haloalkynyl, (dC 7 ) Haloalkoxy- (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -haloalkyl, (C 1 -C 4 ) -haloalkoxy- (C 1 -C 7 ) -haloalkyl, (C 1 -C 7 ) alkylthio (C 1 -C 7) alkyl, (dC 7) -Haloalkylthio- (Ci-C7) alkyl,
R3 und R4 unabhängig voneinander für Wasserstoff, Halogen, (d-C7)- Alkyl, (C3-C7)-Cycloalkyl, (C4-C7)-Cycloalkenyl, (C2-C7)-Alkenyl, (C2-C7)-Alkinyl, (C2-C7)-Alkenyl-(d-C7)-alkyl, (C2-C7)-Alkinyl-(d-C7)-alkyl, (C1-C7)- Alkoxy-(Ci-C7)-alkyl, Hydroxy-(Ci-C7)-alkyl. (d-C7)-Haloalkyl, (C2-C7)- Haloalkenyl, (C2-C7)-Haloalkinyl, (CrC7)-Haloalkoxy-(Ci-C7)-alkyl, R 3 and R 4 are independently hydrogen, halogen, (dC 7) - alkyl, (C 3 -C 7) cycloalkyl, (C 4 -C 7) -cycloalkenyl, (C 2 -C 7) alkenyl, ( C 2 -C 7) -alkynyl, (C 2 -C 7) alkenyl (dC 7) alkyl, (C 2 -C 7) alkynyl (dC 7) alkyl, (C1-C7) - alkoxy - (Ci-C 7 ) -alkyl, hydroxy (Ci-C 7 ) -alkyl. (dC 7) -haloalkyl, (C2-C7) - haloalkenyl, (C 2 -C 7) haloalkynyl, (CrC 7) haloalkoxy (Ci-C7) alkyl,
(Ci-C7)-Alkoxy-(CrC7)-haloalkyl, (Ci-C7)-Haloalkoxy-(d-C7)-haloalkyl, (Ci-C7)-Alkylthio-(Ci-C7)-alkyl, (d-C7)-Haloalkylthio-(Ci-C7)-alkyl stehen, R5 für Hydroxy, (Ci-C7)-Alkoxy. Aryloxy, (C3-C7)-Cycloalkyloxy, (C2-C7)- Alkenyloxy, (C2-C7)-Alkenyl-(Ci-C7)-alkyloxy, (Ci-C7)-Alkoxy-(d-C7)- alkyloxy, (Ci-C7)-Alkylcarbonyloxy, Arylcarbonyloxy, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -haloalkyl, (C 1 -C 7 ) -haloalkoxy- (C 1 -C 4 ) -haloalkyl, (C 1 -C 7 ) -alkylthio (C 1 -C 7 ) -alkyl, (dC 7 ) -haloalkylthio (C 1 -C 7 ) -alkyl, R 5 is hydroxy, (C 1 -C 7 ) -alkoxy. Aryloxy, (C 3 -C 7) cycloalkyloxy, (C2-C7) - alkenyloxy, (C 2 -C 7) alkenyl (Ci-C7) alkyloxy, (Ci-C7) alkoxy (dC 7 ) alkyloxy, (C 1 -C 7 ) -alkylcarbonyloxy, arylcarbonyloxy,
Heteroarylcarbonyloxy, (C3-C7)-Cycloalkylcarbonyloxy, (C1-C7)- Alkoxycarbonyloxy, (C2-C7)-Alkenyloxycarbonyloxy, Aryloxy-(Ci-C7)- alkyloxy, Aryl-(Ci-C7)-alkyloxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkoxy-(Ci-C7)- alkyloxy, (Ci-C7)-Alkylthio-(Ci-C7)-alkyioxy, Tris[(CrC7)-alkyl]silyioxy, (Ci-C7)-Alkyl-Bis[(Ci-C7)-alkyl]silyloxy, (Ci-C7)-Alkyl-bis(Aryl)silyloxy, Aryl-bis[(Ci-C7)— alkyl]silyloxy, Cycloalkyl-bis[(Ci-C7)-alkyl]silyloxy, Halo- bis[(Ci-C7)-alkyl]silyloxy, Tris[(Ci-C7)-alkyl]silyl-(Ci-C7)-alkoxy-(Ci-C7)- alkyloxy, steht, Heteroarylcarbonyloxy, (C3-C 7) cycloalkylcarbonyloxy, (C1-C7) - alkoxycarbonyloxy, (C2-C7) -Alkenyloxycarbonyloxy, aryloxy (Ci-C7) - alkyloxy, aryl- (Ci-C7) alkyloxy, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -alkyloxy, (C 1 -C 7 ) -alkylthio (C 1 -C 7 ) -alkyloxy, tris [(C 1 -C 7 ) -alkyl] silyioxy, (C 1 -C 7 ) -alkyl-bis [(C 1 -C 7 ) -alkyl] silyloxy, (C 1 -C 7 ) -alkyl-bis (aryl) silyloxy, aryl-bis [(ci) C 7 ) alkyl] silyloxy, cycloalkyl bis [(Ci-C 7 ) alkyl] silyloxy, halo bis [(Ci-C 7 ) alkyl] silyloxy, tris [(Ci-C 7 ) alkyl] silyl (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -alkyloxy,
R6 für Nitro, Amino, Hydroxy, Hydrothio, Thiocyanato, Isothiocyanato, R 6 is nitro, amino, hydroxy, hydrothio, thiocyanato, isothiocyanato,
Halogen, (CrC7)-Alkyl, (C3-C7)-Cycloalkyl, (C2-C7)-Alkenyl, (C4-C7)- Cycloalkenyl, (C2-C7)-Alkinyl, Aryl-(C2-C7)-alkinyl, Tris[(Ci-C7)-aikyl]silyl- (C2-C7)-alkinyl, Aryl, Aryl-(d-C7)-alkyl, Aryl-(CrC7)-alkoxy, Heteroaryl, (CrC7)-Haloalkyl, (C3-C7)-Halocycloalkyl, (C2-C7)-Haloalkenyl, (C1-C7)- Alkoxy, (Ci-C7)-Haloalkoxy, Aryloxy, Heteroaryloxy, (C3-C7)- Cycloalkyloxy, (C3-C7)-Cycloalkyl-(Ci-C7)-alkoxy, (C2-C7)- (C2-C7)- Alkenyloxy, (C2-C7)-Alkinyl-(C2-C7)-alkyloxy, Hydroxy-(Ci-C7)-alkyl, Halogen, (C 1 -C 7 ) -alkyl, (C 3 -C 7 ) -cycloalkyl, (C 2 -C 7 ) -alkenyl, (C 4 -C 7 ) -cycloalkenyl, (C 2 -C 7 ) -alkynyl, aryl- C2-C7) alkynyl, tris [(Ci-C7) -alkyl] silyl (C 2 -C 7) alkynyl, aryl, aryl (dC 7) alkyl, aryl (-C 7) alkoxy , heteroaryl, (CrC 7) -haloalkyl, (C 3 -C 7) halocycloalkyl, (C 2 -C 7) haloalkenyl, (C1-C7) - alkoxy, (Ci-C7) haloalkoxy, aryloxy, heteroaryloxy , (C3-C7) - cycloalkyloxy, (C 3 -C 7) cycloalkyl (Ci-C7) alkoxy, (C 2 -C 7) - (C 2 -C 7) - alkenyloxy, (C 2 - C 7 ) -alkynyl- (C 2 -C 7 ) -alkyloxy, hydroxy- (C 1 -C 7 ) -alkyl,
(Ci-C7)-Alkoxy-(Ci-C7)-alkyl, Aryloxy-(CrC7)-alkyl, Heteroaryloxy-(CrC7)- alkyl, (Ci-C7)-Alkylthio, (d-C7)-Haloalkylthio, (d-C7)-Alkoxycarbonyl- (Ci-C7)-alkylthio, Arylthio, (C3-C7)-Cycloalkylthio, Heteroarylthio, (C1-C7)- Alkylthio-(d-C7)-alkyl, (Ci-C7)-Alkylamino, Bis[(Ci-C7)-alkyl]amino, (C2-C7)-Alkenylamino, (C3-C7)-Cycloalkylamino, (C1-C7)- Alkylcarbonylamino, (C3-C7)-Cycloalkylcarbonylamino, (Ci-C7) alkoxy (Ci-C7) alkyl, aryloxy- (CrC 7) alkyl, heteroaryloxy (-C 7) - alkyl, (Ci-C7) -alkylthio, (dC 7) - haloalkylthio, (dC 7) alkoxycarbonyl (Ci-C7) alkylthio, arylthio, (C 3 -C 7) cycloalkylthio, heteroarylthio, (C1-C7) - alkylthio (dC 7) alkyl, (Ci- C 7 ) alkylamino, bis [(C 1 -C 7 ) alkyl] amino, (C 2 -C 7 ) alkenylamino, (C 3 -C 7 ) cycloalkylamino, (C 1 -C 7 ) -alkylcarbonylamino, (C 3 -C 7 ) cycloalkylcarbonylamino,
Arylcarbonylamino, Heteroarylcarbonylamino, Formylamino, (C1-C7)- Haloalkylcarbonylamino, (Ci-C7)-Alkoxycarbonylamino, (C1-C7)- Alkylaminocarbonylamino, (Ci-C7)-Alkyl[(Ci-C7)- Alkyljaminocarbonylamino, (Ci-C7)-Alkylsulfonylamino, (C3-C7)- Cycloalkylsulfonylamino, Arylsulfonylamino, Hetarylsulfonylamino, Sulfonyl-(Ci-C7)-haloalkylamino, Amino-(Ci-C7)-alkylsulfonyl, Amino- (CrC7)-haloalkylsulfonyl, (Ci-C7)-Alkylaminosulfonyl, Bis[(d-C7)- alkyljaminosulfonyl, (C3-C7)-Cycloalkylaminosulfonyl, (C1-C7)- Haloalkylaminosulfonyl, Heteroarylaminosulfonyl, Arylaminosulfonyl, Aryl- (Ci-C7)-alkylaminosulfonyl, (Ci-C7)-Alkylsulfonyl, (C3-C7)- Cycloalkylsulfonyl, Arylsulfonyl. (d-C7)-Alkylsulfinyl, (C3-C7)- Cycloalkylsulfinyl, Arylsulfinyl, N.S-Bis[(Ci-C7)-alkyl]sulfonimidoyl, S- (CrC )-Alkylsulfonimidoyl, (C1-C7)- Alkylsulfonylaminocarbonyl, (C3-C7)- Cycloalkylsulfonylaminocarbonyl, Aryl-(Ci-C7)-alkylcarbonylamino, (C3-C )-Cycloalkyl-(CrC7)-alkylcarbonylamino, Heteroarylcarbonylamino, (Ci-C7)-Alkoxy-(Ci-C )-alkylcarbonylamino, Hydroxy-(d-C7)- alkylcarbonylamino, (Ci-C7)-Alkoxycarbonylamino-(Ci-C7)- alkylcarbonylamino, Cyano, Cyano-(Ci-C7)-alkyl, Hydroxycarbonyl, Arylcarbonylamino, heteroarylcarbonylamino, formylamino, (C 1 -C 7 ) -haloalkylcarbonylamino, (C 1 -C 7 ) -alkoxycarbonylamino, (C 1 -C 7 ) -alkylaminocarbonylamino, (C 1 -C 7 ) -alkyl [(C 1 -C 7 ) -alkyl-aminocarbonyl-amino, ( Ci-C 7) alkylsulfonylamino, (C 3 -C 7) - cycloalkylsulfonylamino, arylsulfonylamino, Hetarylsulfonylamino, sulfonyl (Ci-C 7) -haloalkylamino, amino (Ci-C7) alkylsulphonyl, amino- (CrC 7) -haloalkylsulfonyl, (Ci-C 7 ) -alkylaminosulfonyl, bis [(dC 7 ) -alkyljaminosulfonyl, (C 3 -C 7 ) -cycloalkylaminosulfonyl, (C 1 -C 7 ) - Haloalkylaminosulfonyl, heteroarylaminosulfonyl, arylaminosulfonyl, aryl- (C 1 -C 7 ) -alkylaminosulfonyl, (C 1 -C 7 ) -alkylsulfonyl, (C 3 -C 7 ) -cycloalkylsulfonyl, arylsulfonyl. (C 1 -C 4 ) -alkylsulfinyl, (C 3 -C 7 ) -cycloalkylsulfinyl, arylsulfinyl, NS-bis [(C 1 -C 7 ) -alkyl] sulfonimidoyl, S- (C 1 -C 4) -alkylsulfonimidoyl, (C 1 -C 7 ) -alkylsulfonylaminocarbonyl, (C3 -C7) - cycloalkylsulfonylaminocarbonyl, aryl- (Ci-C 7 ) -alkylcarbonylamino, (C3-C) -cycloalkyl- (CrC 7 ) -alkylcarbonylamino, heteroarylcarbonylamino, (Ci-C 7 ) -alkoxy- (Ci-C) -alkylcarbonylamino , Hydroxy- (C 1 -C 7 ) -alkylcarbonylamino, (C 1 -C 7 ) -alkoxycarbonylamino- (C 1 -C 7 ) -alkylcarbonylamino, cyano, cyano- (C 1 -C 7 ) -alkyl, hydroxycarbonyl,
(Ci-C7)-Alkoxycarbonyl, (C;i-C7)-Cycloalkoxycarbonyl, (C3-C7)-Cycloalkyl- (Ci-C7)-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C7)-alkoxycarbonyl, (C2-C7)-Alkenyloxycarbonyl, (C2-C7)-Alkinyloxycarbonyl, (C1-C7)- Haloalkyloxycarbonyl, (Ci-C7)-Alkoxy-(CrC )-alkoxycarbonyl, (C2-C7)- Alkenyloxy-(Ci-C )-alkoxycarbonyl, (Ci-C7)-Alkylamino-(Ci-C )- alkoxycarbonyl, Tris[(Ci-C7)-alkyl]silyloxy-(CrC )-alkoxycarbonyl, Bis[(CrC7)-Alkyl]amino-(Ci-C7)-alkoxycarbonyl, (Ci-C7)-Alkyl[(d-C7)- alkyl]amino-(Ci-C7)-alkoxycarbonyl, Cyano-(Ci-C7)-alkoxycarbonyl, Heterocyclyl-N-(Ci-C7)-alkoxycarbonyl, Heteroaryloxycarbonyl, (Ci-C 7) alkoxycarbonyl, (C; iC 7) cycloalkoxycarbonyl, (C3-C7) -cycloalkyl- (Ci-C 7) alkoxycarbonyl, aryloxycarbonyl, aryl- (Ci-C7) -alkoxycarbonyl, ( C 2 -C 7 ) alkenyloxycarbonyl, (C 2 -C 7 ) -alkynyloxycarbonyl, (C 1 -C 7 ) -haloalkyloxycarbonyl, (C 1 -C 7 ) -alkoxy- (C 1 -C 4) -alkoxycarbonyl, (C 2 -C 7 ) -alkenyloxy- (Ci -C) -alkoxycarbonyl, (C 1 -C 7 ) -alkylamino- (C 1 -C 4) -alkoxycarbonyl, tris [(C 1 -C 7 ) -alkyl] silyloxy- (C 1 -C 4) -alkoxycarbonyl, bis [(C 1 -C 7 ) -alkyl ] amino- (Ci-C 7) alkoxycarbonyl, (Ci-C7) alkyl [(dC 7) - alkyl] amino- (Ci-C 7) alkoxycarbonyl, cyano (Ci-C 7) alkoxycarbonyl, Heterocyclyl-N- (C 1 -C 7 ) -alkoxycarbonyl, heteroaryloxycarbonyl,
Heteroaryl-(Ci-C7)-alkoxycarbonyl, Heterocyclyl-(Ci-C7)-alkoxycarbonyl, Heterocyclyl oxycarbonyl , (C2-C7)-Al kenyl-(Ci-C7)-al koxycarbonyl , (C2-C7)-Alkinyl-(Ci-C7)-alkoxycarbonyl, Aryl-(C2-C )-alkinyloxycarbonyl, Aryl-(C2-C )-alkenyloxycarbonyl, Aminocarbonyl, (d-C7)- Alkylaminocarbonyl, Bis[(Ci-C7)-alkyl]aminocarbonyl, (Ci-C7)- Alkyl[(d-C7)-Alkyl]aminocarbonyl, (Ci-C7)-Alkyl[(Ci-C7)- Alkoxy]aminocarbonyl, (C2-C7)-Alkenylaminocarbonyl, (C3-C7)- Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C7)- alkylaminocarbonyl, Heteroaryl-(Ci-C7)-alkylaminocarbonyl, Cyano- (Ci-C7)-alkylaminocarbonyl, (Ci-C7)-Haloalkylaminocarbonyl, (C2-C7)- Alkinyl-(CrC7)-alkylaminocarbonyl, (Ci-C )- Alkoxycarbonylaminocarbonyl, Aryl-(Ci-C )- alkoxycarbonylaminocarbonyl, Hydroxycarbonyl-(Ci-C )-alkyl, (d-C )- Alkoxycarbonyl-(d-C7)-alkyl, (C3-C7)-Cycloalkoxycarbonyl-(CrC7)-alkyl, (C3-C7)-Cycloalkyl-(Ci-C7)-alkoxycarbonyl-(CrC7)-alkyl, (C2-C7)- Alkenyloxycarbonyl-(Ci-C7)-aikyl, Aryl-(Ci-C7)-alkoxycarbonyl-(Ci-C7)- alkyl, (Ci-C7)-Alkylaminocarbonyl-(Ci-C7)-alkyl, Aminocarbonyl-(Ci-C7)- alkyl, Bis[(Ci-C7)-alkyl]aminocarbonyl-(Ci-C7)-alkyl, (C3-C7)- Cycloalkylaminocarbonyl-(CrC7)-alkyl, Aryl-(CrC7)-alkylaminocarbonyl- (d-C7)-alkyl, Heteroaryi-(CrC7)-alkylaminocarbonyl-(Ci-C7)-alkyl, Cyano-(Ci-C7)-alkylaminocarbonyl-(Ci-C7)-alkyL (C1-C7)- Haloalkylaminocarbonyl-(Ci-C7)-alkyl, (C2-C7)-Aikinyl-(Ci-C7)- alkylaminocarbonyl-(Ci-C7)-alkyl, (C3-C7)-Cycloalkyl-(Ci-C7)- alkylaminocarbonyl-(Ci-C7)-alkyl, (Ci-C7)-Alkoxycarbonylaminocarbonyl- (Ci-C7)-alkyl, Aryl-(Ci-C7)-alkoxycarbonylaminocarbonyl-(Ci-C7)-alkyl, (Ci-C7)-Alkoxycarbonyl-(CrC7)-alkylaminocarbonyl, Hydroxycarbonyl- (Ci-C7)-alkylaminocarbonyl, Aryl-(Ci-C7)-alkoxycarbonyl-(Ci-C7)- alkylaminocarbonyl, Aminocarbonyl-(Ci-C7)-alkylaminocarbonyl, (C1-C7)- Alkylaminocarbonyl-(Ci-C7)-alkylaminocarbonyl? Heteroaryl- (Ci-C 7 ) -alkoxycarbonyl, heterocyclyl- (Ci-C 7 ) -alkoxycarbonyl, heterocyclyl oxycarbonyl, (C 2 -C 7 ) -Al kenyl- (Ci-C 7 ) -al koxycarbonyl, (C 2 -C 7 ) Alkynyl (C 1 -C 7 ) alkoxycarbonyl, aryl- (C 2 -C 4 ) alkynyloxycarbonyl, aryl- (C 2 -C 4) alkenyloxycarbonyl, aminocarbonyl, (C 1 -C 7 ) -alkylaminocarbonyl, bis [(C 1 -C 7 ) alkyl] aminocarbonyl, (Ci-C7) - alkyl [(dC 7) alkyl] aminocarbonyl, (Ci-C 7) alkyl [(Ci-C7) - alkoxy] aminocarbonyl, (C2-C7) - alkenylaminocarbonyl, (C3-C7) - cycloalkylaminocarbonyl, arylaminocarbonyl, aryl (Ci-C7) - alkylaminocarbonyl, heteroaryl (Ci-C 7) alkylaminocarbonyl, cyano (Ci-C 7) alkylaminocarbonyl, (Ci-C 7) -Haloalkylaminocarbonyl, (C2-C7) - alkynyl (-C 7) alkylaminocarbonyl, (Ci-C) - alkoxycarbonylaminocarbonyl, aryl (Ci-C) - alkoxycarbonylaminocarbonyl, hydroxycarbonyl- (Ci-C) alkyl, ( dC) - alkoxycarbonyl (dC 7) alkyl, (C3-C 7) -Cycloalkoxycarbonyl- (-C 7) alkyl, (C 3 -C 7) cycloalkyl (Ci-C7) alkoxycarbonyl (CrC 7 ) -alkyl, (C 2 -C 7 ) - Alkenyloxycarbonyl- (C 1 -C 7) -alkyl, aryl- (C 1 -C 7) -alkoxycarbonyl- (C 1 -C 7) -alkyl, (C 1 -C 7) -alkylaminocarbonyl- (C 1 -C 7) -alkyl, aminocarbonyl- (C 1 -C 7 ) alkyl, bis [(Ci-C7) alkyl] aminocarbonyl (Ci-C 7 ) -alkyl, (C3-C7) - Cycloalkylaminocarbonyl- (CrC7) -alkyl, aryl- (CrC7) -alkylaminocarbonyl- (d-) C7) -alkyl, heteroaryi (C 1 -C 7) -alkylaminocarbonyl- (C 1 -C 7) -alkyl, cyano- (C 1 -C 7) -alkylaminocarbonyl- (C 1 -C 7) -alkyL (C 1 -C 7) -haloalkylaminocarbonyl- (C 1 -C 4) -alkyl) 7) alkyl, (C2-C7) -Aikinyl- (Ci-C7) - alkylaminocarbonyl (Ci-C7) alkyl, (C3-C7) -cycloalkyl- (Ci-C7) - alkylaminocarbonyl ( C 1 -C 7) -alkyl, (C 1 -C 7) -alkoxycarbonylaminocarbonyl- (C 1 -C 7) -alkyl, aryl- (C 1 -C 7) -alkoxycarbonylaminocarbonyl- (C 1 -C 7) -alkyl, (C 1 -C 7) -alkoxycarbonyl- C 1 -C 7) -alkylaminocarbonyl, hydroxycarbonyl- (C 1 -C 7) -alkylaminocarbonyl, aryl- (C 1 -C 7) -alkoxycarbonyl- (C 1 -C 7) -alkylaminocarbonyl, aminocarbonyl- (C 1 -C 7) -alkylaminocarbonyl, (C 1 -C 7) -alkylaminocarbonyl - (C 1 -C 7) -alkylaminocarbonyl ?
(C3-C7)-Cycloalkylaminocarbonyl-(Ci-C7)-alkylaminocarbonyl, (C3-C7)- Cycloalkyi-(Ci-C7)-alkyiaminocarbonyl, (C3-C7)-Cycloalkyl-(Ci-C7)- alkyiaminocarbonyl-(Ci-C7)-alkyl, (C3-C7)-Cycloalkyl-(Ci-C7)- alkylaminocarbonyl-(Ci-C7)-alkylaminocarbonyl, (C2-C7)-Alkenyl-(Ci-C7)- alkylaminocarbonyl, (C2-C7)-Alkenylaminocarbonyl-(Ci-C7)-alkyl, (C2-C7)- Alkenyl-(Ci-C7)-alkylaminocarbony!-(Ci-C7)-alkyl, (Ci-C7)-AlkylcarbonyL (C3-C7)-Cycloalkylcarbonyl, Arylcarbonyl, Formyl, Hydroxyiminomethyl, Aminoiminomethyl, (Ci-C7)-Alkoxyiminomethyl, (C1-C7)- Alkylaminoiminomethyl, Bis[(Ci-C7)-alkyl]aminoiminomethyl, (C3-C7)- Cycloalkoxyiminomethyl, (C;rC7)-Cycloalkyl-(Ci-C7)-alkoximinomethyl, Aryloximinomethyl, Aryl-(Ci-C7)-alkoxyiminomethyl, Aryl-(Ci-C7)- alkylaminoiminomethyl, (C2-C7)-Alkenyloxyiminomethyl, (C 3 -C 7 ) -cycloalkylaminocarbonyl- (C 1 -C 7 ) -alkylaminocarbonyl, (C 3 -C 7 ) -cycloalkyl (C 1 -C 7 ) -alkylaminocarbonyl, (C 3 -C 7 ) -cycloalkyl- (C 1 -C 7 ) -alkylaminocarbonyl - (C 1 -C 7 ) -alkyl, (C 3 -C 7 ) -cycloalkyl- (C 1 -C 7 ) -alkylaminocarbonyl- (C 1 -C 7 ) -alkylaminocarbonyl, (C 2 -C 7 ) -alkenyl- (C 1 -C 7 ) -alkylaminocarbonyl , (C 2 -C 7) -alkenylaminocarbonyl- (C 1 -C 7) -alkyl, (C 2 -C 7) -alkenyl- (C 1 -C 7) -alkylaminocarbonyl- (C 1 -C 7) -alkyl, (C 1 -C 7) -alkylcarbonyL ( C3-C7) -cycloalkylcarbonyl, arylcarbonyl, formyl, hydroxyiminomethyl, aminoiminomethyl, (C 1 -C 7) -alkoxyiminomethyl, (C 1 -C 7) -alkylaminoiminomethyl, bis [(C 1 -C 7) -alkyl] aminoiminomethyl, (C 3 -C 7) -cycloalkoxyiminomethyl , (C; r C7) -cycloalkyl- (C 1 -C 7) -alkoximinomethyl, aryloximinomethyl, aryl- (C 1 -C 7) -alkoxyiminomethyl, aryl- (C 1 -C 7) -alkylaminoiminomethyl, (C 2 -C 7) -alkenyloxyiminomethyl,
Arylaminoiminomethyi, Arylsulfonylaminoiminomethyl, Heteroaryl-(Ci-C7)- alkyl, Heterocyclyl-(Ci-C7)-alkyl, Hydroxycarbonylheterocyclyl, (C1-C7)- Alkoxycarbonylheterocyclyl, (C2-C7)-Alkenyloxycarbonylheterocyclyl, (C2-C7)-Alkenyl-(Ci-C7)-alkoxycarbonylheterocyclyl, Aryl-(d-C7)- alkoxycarbonylheterocyclyl, (C3-C7)-Cycloalkoxycarbonylheterocyclyl, (C3-C7)-Cycloalkyl-(CrC7)-alkoxycarbonylheterocyclyl. Arylaminoiminomethyl, arylsulfonylaminoiminomethyl, heteroaryl- (C 1 -C 7) -alkyl, heterocyclyl- (C 1 -C 7) -alkyl, hydroxycarbonylheterocyclyl, (C 1 -C 7) -alkoxycarbonylheterocyclyl, (C 2 -C 7) -alkenyloxycarbonylheterocyclyl, (C 2 -C 7) -alkenyl- (C 1 -C 7) -alkoxycarbonylheterocyclyl, aryl- (C 1 -C 7) -alkoxycarbonylheterocyclyl, (C 3 -C 7) -cycloalkoxycarbonylheterocyclyl, (C 3 -C 7) -cycloalkyl- (C 1 -C 7) -alkoxycarbonylheterocyclyl.
Aminocarbonylheterocyclyl, (CrC7)-Alkylaminocarbonylheterocyclyl, Bis[(CrC7)-Alkyl]aminocarbonylheterocyclyl, (C3-C7)- Cycloalkylaminocarbonylheterocyclyl, Aryl-(Ci-C-7)- alkylaminocarbonylheterocyclyl, (C2-C7)-Aminocarbonylheterocyclyl, (CrC7) -alkylaminocarbonylheterocyclyl, bis [(CrC7) -alkyl] aminocarbonylheterocyclyl, (C3-C7) - Cycloalkylaminocarbonylheterocyclyl, aryl- (Ci-C-7) -alkylaminocarbonylheterocyclyl, (C2-C7) -
Alkenylaminocarbonylheterocyclyl, Hydroxycarbonylheterocyc!yl-(Ci-C7)- alkyl, (Ci-C7)-Alkoxycarbonylheterocyclyl-(CrC7)-alkyl, Hydroxycarbonyl- (C3-C7)-cycloalkyl-(Ci-C7)-alkyl, (Ci-C7)-Alkoxycarbonyl-(C3-C7)- cycloalkyl-(Ci-C7)-alkyl, Hydroxyaminocarbonyl, (C1-C7)- Alkoxyaminocarbonyl, Aryl-(Ci-C7)-alkoxyaminocarbonyi, Heterocyclyl, (Ci-C7)-A!kylcarbonyloxy, Arylcarbonyloxy, Heteroarylcarbonyloxy, (C3-C7)-Cycloalkylcarbonyloxy, (Ci-C7)-Alkoxycarbonyloxy, (C2-C7)- Alkenyloxycarbonyloxy, Aminosulfonyl, (Ci-C7)-Alkoxycarbonyl- heterocyclyl-N-carbonyl, (Ci-C7)-Alkoxycarbonyl-(Ci-C7)-alkyl- heterocyclylidenaminocarbonyl, (CrC7)-Alkoxycarbonylheterocyclyliden- (Ci-C7)-alkylaminocarbonyl (Ci-C7)-Alkoxycarbonyl-(Ci-C7)-Alkyl((Ci-C7)- alkyl)aminocarbonyl, (Ci-C7)-Alkoxycarbonyl-(C3-C7)- cycloalkylidenaminocarbonyl, Heterocyclyl-N-carbonyl, (CrC-7)-Alkoxy- (Ci-C7)-alkylaminocarbonyl steht, Alkenylaminocarbonylheterocyclyl, hydroxycarbonylheterocyclyl (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -alkoxycarbonylheterocyclyl- (C 1 -C 7) -alkyl, hydroxycarbonyl- (C 3 -C 7 ) -cycloalkyl- (C 1 -C 7 ) -alkyl, (Ci -C 7 ) -alkoxycarbonyl- (C 3 -C 7 ) -cycloalkyl- (C 1 -C 7 ) -alkyl, hydroxyaminocarbonyl, (C 1 -C 7 ) -alkoxyaminocarbonyl, aryl- (C 1 -C 7 ) -alkoxyaminocarbonyi, heterocyclyl, (C 1 -C 7 ) ) -Alcarbonyloxy, arylcarbonyloxy, heteroarylcarbonyloxy, (C 3 -C 7) -cycloalkylcarbonyloxy, (C 1 -C 7) -alkoxycarbonyloxy, (C 2 -C 7) -alkenyloxycarbonyloxy, aminosulfonyl, (C 1 -C 7) -alkoxycarbonyl-heterocyclyl-N-carbonyl, (C 1 -C 7 ) -alkoxycarbonyl- (C 1 -C 7 ) -alkyl-heterocyclylideneaminocarbonyl, (C 1 -C 7 ) -alkoxycarbonylheterocyclylidene- (C 1 -C 7 ) -alkylaminocarbonyl (C 1 -C 7 ) -alkoxycarbonyl- (C 1 -C 7 ) -alkyl ((C 1 -C 4 ) -alkyl C 1 -C 7 ) -alkyl) aminocarbonyl, (C 1 -C 7) -alkoxycarbonyl- (C 3 -C 7) -cycloalkylideneaminocarbonyl, heterocyclyl-N-carbonyl, (C 1 -C 7) -alkoxy- (C 1 -C 7) -alkylaminocarbonyl,
R7, R8, R9, R10, R11 und R12 unabhängig voneinander für Wasserstoff, (C1-C7)- Alkyl, (C3-C7)-Cycloalkyl, (C2-C7)-Alkenyl, (C2-C7)-Alkenyl-(C,-C7)-alkyl, (Ci-C7)-Alkoxy-(Ci-C7)-alkyl, Hydroxy-(Ci-C7)-alkyl, (Ci-C7)-Haioalkyl, (C2-C7)-Haloalkenyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-alkyi, (Ci-C7)-Alkoxy- (Ci-C7)-haloalkyl. (Ci-C7)-Haloalkoxy-(Ci-C7)-haloalkyl, (Ci-C7)-Alkoxy, (d-C7)-Alkylthio, (CrC7)-Alkylamino, Halogen, Amino stehen, wobei mindestens eine der Gruppen R7, R8, R9, R10, R1 und R12 nicht für Wasserstoff steht und R 7, R 8, R 9, R 10, R 11 and R 12 independently represent hydrogen, (C1-C7) - alkyl, (C3-C 7) -cycloalkyl, (C 2 -C 7) alkenyl, ( C2-C7) alkenyl (C, C7) alkyl, (Ci-C7) alkoxy (Ci-C7) alkyl, hydroxy (Ci-C7) alkyl, (Ci-C 7 ) -Haioalkyl, (C 2 -C 7 ) -haloalkenyl, (Ci-C7) -haloalkoxy- (Ci-C 7 ) -alkyi, (Ci-C 7 ) -alkoxy- (Ci-C 7 ) -haloalkyl. (C 1 -C 7 ) -haloalkoxy- (C 1 -C 7 ) -haloalkyl, (C 1 -C 7 ) -alkoxy, (C 1 -C 7 ) -alkylthio, (C 1 -C 7 ) -alkylamino, halogen, amino, where at least one of the groups R 7 , R 8 , R 9 , R 10 , R 1 and R 12 are not hydrogen and
R3 und R4 mit dem Atom, an das sie gebunden sind, eine exo-Alkylidengruppe oder einen vollständig gesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 6-gliedrigen Ring bilden, R 3 and R 4 with the atom to which they are attached, an exo-alkylidene group or a fully saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 3 to 6 form a -ligmoid ring,
R1 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig R 1 and R 11 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, saturated or partially saturated, optionally by O (oxygen), S Form (sulfur) or a group NH, NR 37 interrupted and optionally further substituted 5 to 7-membered ring,
R1 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig R 1 and R 9 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S saturated or partially saturated, optionally by O (oxygen), S
(Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, (Sulfur) or a group NH, NR 37 form interrupted and optionally further substituted 3 to 7-membered ring,
R3 und R7 mit den Atomen, an die sie gebunden sind, einen vollständig R 3 and R 7 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S saturated or partially saturated, optionally by O (oxygen), S
(Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, Form (sulfur) or a group NH, NR 37 interrupted and optionally further substituted 5 to 7-membered ring,
R3 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig R 3 and R 11 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S saturated or partially saturated, optionally by O (oxygen), S
(Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, (Sulfur) or a group NH, NR 37 form interrupted and optionally further substituted 3 to 7-membered ring,
R1 und R3 mit den Atomen, an die sie gebunden sind, einen vollständig R 1 and R 3 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S saturated or partially saturated, optionally by O (oxygen), S
(Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, Form (sulfur) or a group NH, NR 37 interrupted and optionally further substituted 5 to 7-membered ring,
R7 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig R 7 and R 11 complete with the atoms to which they are attached
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S saturated or partially saturated, optionally by O (oxygen), S
(Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, Form (sulfur) or a group NH, NR 37 interrupted and optionally further substituted 5 to 7-membered ring,
R3 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig R 3 and R 9 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S saturated or partially saturated, optionally by O (oxygen), S
(Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, R7 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, (Sulfur) or a group NH, NR 37 form interrupted and optionally further substituted 3 to 7-membered ring, R 7 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
R13, R14, R15 und R16 unabhängig voneinander für Wasserstoff, Halogen, Nitro, Amino, Cyano, (Ci-C7)-Alkyl, Aryl, Heteroaryl, (C3-C7)-Cycloalkyl, (C4-C7)- Cycloalkenyl. (C2-C7)-Alkenyl, (C2-C7)-Alkinyl, (C2-C7)-Alkenyl-(Ci-C7)- alkyl, (C2-C7)-Alkinyl-(Ci-C7)-alkyl, Hydroxy, (Ci-C7)-Alkoxy, (C1-C7)- Alkoxy-(Ci-C7)-alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkyl, Hydroxy-(Ci-C7)- alkyl, (CrC7)-Haloalkoxy, (Ci-C7)-Haloalkyl, (C2-C7)-Haloalkenyl, (C2-C7)- Haloalkinyl. (Ci-C7)-Haloalkoxy-(CrC7)-alkyl, (Ci-C7)-Alkoxy-(Ci-C7)- haloalkyl, (Ci-C7)-Haloalkoxy-(d-C7)-haloalkyl, Hydrothio, (C1-C7)- Alkylthio, (d-C7)-Haloalkylthio, (Ci-C7)-Alkylthio-(Ci-C7)-alkyl, (C1-C7)- Haloalkylthio-(d-C7)-alkyl, (Ci-C7)-Alkylamino, Bis-[(Ci-C7)-alkyl]amino, (C2-C7)-Alkenylamino, (C3-C7)-Cycloalkylamino, (C1-C7)- Alkylcarbonylamino, (C3-C7)-Cycloalkylcarbonylamino, R 13, R 14, R 15 and R 16 are independently hydrogen, halogen, nitro, amino, cyano, (Ci-C7) alkyl, aryl, heteroaryl, (C 3 -C 7) cycloalkyl, (C 4 -C 7 ) - cycloalkenyl. (C2-C7) alkenyl, (C 2 -C 7) -alkynyl, (C 2 -C 7) alkenyl (Ci-C7) - alkyl, (C 2 -C 7) alkynyl (C -C 7) alkyl, hydroxy, (Ci-C7) alkoxy, (C1-C7) - alkoxy (Ci-C7) alkoxy, (Ci-C7) alkoxy (Ci-C 7) alkyl, hydroxy (Ci-C7) - alkyl, (CrC 7) haloalkoxy, (Ci-C7) haloalkyl, (C 2 -C 7) haloalkenyl, (C2-C7) - haloalkynyl. (C 1 -C 7 ) -haloalkoxy- (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -haloalkyl, (C 1 -C 7 ) -haloalkoxy- (C 1 -C 4 ) -haloalkyl, Hydrothio, (C 1 -C 7 ) -alkylthio, (C 1 -C 4 ) -haloalkylthio, (C 1 -C 7 ) -alkylthio (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -haloalkylthio (C 1 -C 7 ) -alkyl, (Ci-C7) alkylamino, - bis [(Ci-C 7) alkyl] amino, (C 2 -C 7) alkenylamino, (C3-C7) cycloalkylamino, (C1-C7) - alkylcarbonylamino, (C 3 -C 7 ) -cycloalkylcarbonylamino,
Arylcarbonylamino, Heteroarylcarbonylamino, Formylamino, (C1-C7)- Haloalkylcarbonylamino, (Ci-C7)-Alkoxycarbonylamino, (C1-C7)- Alkylaminocarbonylamino, (Ci-C7)- Alkyl[(Ci-C7)- Alkyl]aminocarbonylamino, (Ci-C7)-Alkylsulfonylamino, (C3-C7)- Cycloalkylsulfonylamino, Arylsulfonylamino, Hetarylsulfonylamino, Sulfonyl-(Ci-C7)-haloalkylamino, Amino-(CrC7)-alkylsulfonyl, Amino- (Ci-C7)-haloalkylsulfonyl, (Ci-C7)-Alkylaminosulfonyl, Bis[(Ci-C7)- alkyl]aminosulfonyl, (C3-C7)-Cycloalkylaminosulfonyl, (C1-C7)- Haloalkylaminosulfonyl, Heteroarylaminosulfonyl, Arylaminosuifonyl, Aryl- (Ci-C7)-alkylaminosulfonyl, (Ci-C7)-Alkylsulfonyl, (C3-C7)- Cycloalkylsulfonyl, Arylsulfonyl, Hydroxycarbonyl, (C1-C7)- Alkoxycarbonyl, (C3-C7)-Cycloalkoxycarbonyl, (C3-C7)-Cycloalkyl-(Ci-C7)- alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C7)-alkoxycarbonyl, (C2-C7)- Alkenyloxycarbonyl, (C2-C7)-Alkinyloxycarbonyl, Aminocarbonyl, (C1-C7)- Alkylaminocarbonyl, Bis[(CrC7)-alkyl]aminocarbonyl, (C1-C7)- Alkyl[(Ci-C7)-Alkyl]aminocarbonyl, (Ci-C7)-Alkyl[(Ci-C7)- Alkoxy]aminocarbonyl, (C2-C7)-Alkenylaminocarbonyl, (C3-C7)- Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C-7)- alkylaminocarbonyl stehen, Arylcarbonylamino, heteroarylcarbonylamino, formylamino, (C1-C7) - Haloalkylcarbonylamino, (Ci-C 7) alkoxycarbonylamino, (C1-C7) - alkylaminocarbonylamino, (Ci-C7) - alkyl [(Ci-C7) - alkyl] aminocarbonylamino , (Ci-C 7) alkylsulfonylamino, (C3-C7) - cycloalkylsulfonylamino, arylsulfonylamino, Hetarylsulfonylamino, sulfonyl (Ci-C 7) -haloalkylamino, amino (CrC 7) alkylsulfonyl, amino (Ci-C 7) haloalkylsulfonyl, (Ci-C 7) alkylaminosulfonyl, bis [(Ci-C7) - alkyl] aminosulfonyl, (C3-C 7) -Cycloalkylaminosulfonyl, (C1-C7) - Haloalkylaminosulfonyl, heteroarylaminosulfonyl, Arylaminosuifonyl, aryl (C -C 7) alkylaminosulfonyl, (Ci-C7) alkylsulfonyl, (C3-C7) - cycloalkylsulfonyl, arylsulfonyl, hydroxycarbonyl, (C1-C7) - alkoxycarbonyl, (C3-C 7) cycloalkoxycarbonyl, (C3-C 7 ) -cycloalkyl- (Ci-C 7) - alkoxycarbonyl, aryloxycarbonyl, aryl- (Ci-C7) -alkoxycarbonyl, (C 2 -C 7) - alkenyloxycarbonyl, (C 2 -C 7) -alkynyloxycarbonyl, aminocarbonyl, (C1 -C7) - alkylaminocarbonyl, bis [(CrC 7 ) alkyl] aminoc arbonyl, (C1-C7) - alkyl [(Ci-C 7) alkyl] aminocarbonyl, (Ci-C 7) alkyl [(Ci-C7) - alkoxy] aminocarbonyl, (C 2 -C 7) -Alkenylaminocarbonyl , (C3-C7) - Cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (Ci-C-7) -alkylaminocarbonyl,
A1 , A2, A3 und A4 gleich oder verschieden sind und unabhängig voneinander für N (Stickstoff) oder die Gruppierungen C-H, C-CH3, C-F, C-Cl, C-Br, C-l, C-OCF3, C-OCH3, C-CF3, C-CO2H, C-CO2CH3 stehen, wobei jedoch in keinem Fall mehr als zwei N -Atome benachbart sind, A 1 , A 2 , A 3 and A 4 are the same or different and are each independently N (nitrogen) or the groupings CH, C-CH 3 , CF, C-Cl, C-Br, Cl, C-OCF 3, C -OCH3, C-CF3, C-CO2H, C-CO2CH3, but in no case more than two N atoms are adjacent,
R17 und R18 unabhängig voneinander für Wasserstoff, Halogen, (Ci-C7)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (C3-C7)-Cycloalkyl, (C2-C7)-Alkenyl, (C2-C7)-Alkinyl, (CrC7)-Alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkyl, Aryloxy- (Ci-C7)-alkyl, (Ci-C7)-Haloalkoxy, (Ci-C7)-Haloalkyl, (Ci-C7)-Haloalkoxy- (Ci-C7)-alkyl, (Ci-C7)-Alkoxy-(Ci-C7)-haloalkyl, (Ci-C7)-Haloalkoxy- (Ci-C7)-haloalkyl, (CrC7)-Alkylthio, (CrC7)-Haloalkylthio, (C1-C7)- Alkylthio-(Ci-C7)-alkyl, Hydroxycarbonyi, (Ci-C7)-Alkoxycarbonyl, (C3-C7)- Cycloalkoxycarbonyl, (C3-C7)-Cycloalkyl-(CrC7)-alkoxycarbonyl, R 17 and R 18 independently of one another are hydrogen, halogen, (C 1 -C 7) -alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 7 ) -cycloalkyl, (C 2 -C 7 ) -alkenyl, (C 2 -C 7 ) -alkynyl , (C 1 -C 7 ) -alkoxy, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -alkyl, aryloxy- (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -haloalkoxy, (Ci-C 7 ) -haloalkyl, (C 1 -C 7 ) -haloalkoxy- (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -haloalkyl, (C 1 -C 7 ) -haloalkoxy- (Ci-C7) haloalkyl, (CrC 7) alkylthio, (CrC 7) haloalkylthio, (C1-C7) - alkylthio (Ci-C7) alkyl, Hydroxycarbonyi, (Ci-C7) alkoxycarbonyl, ( C 3 -C 7) - cycloalkoxycarbonyl, (C 3 -C 7) -cycloalkyl- (C 1 -C 7) -alkoxycarbonyl,
Aryloxycarbonyl, Aryl-(d-C7)-alkoxycarbonyl, (C2-C7)- Alkenyloxycarbonyl, (C2-C7)-Alkinyloxycarbonyl, Aminocarbonyl, (C1-C7)- Alkylaminocarbonyl, Bis[(Ci-C7)-alkyl]aminocarbonyl, (C1-C7)- Alkyl[(Ci-C7)-Alkyl]aminocarbonyl, (Ci-C7)-Alkyl[(Ci-C7)- Alkoxy]aminocarbonyl, (C2-C7)-Alkenylaminocarbonyl, (C3-C7)- Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C7)- alkylaminocarbonyl stehen, Aryloxycarbonyl, aryl- (C 1 -C 7) -alkoxycarbonyl, (C 2 -C 7) -alkenyloxycarbonyl, (C 2 -C 7) -alkynyloxycarbonyl, aminocarbonyl, (C 1 -C 7) -alkylaminocarbonyl, bis [(C 1 -C 7) -alkyl] aminocarbonyl, (C 1 -C 7 ) -alkyl [(C 1 -C 7 ) -alkyl] aminocarbonyl, (C 1 -C 7 ) -alkyl [(C 1 -C 7 ) -alkoxy] -aminocarbonyl, (C 2 -C 7 ) -alkenylaminocarbonyl, (C 3 -C 7 ) ) - cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 7) -alkylaminocarbonyl,
A5 für S (Schwefel), O (Sauerstoff) oder die Gruppierungen N-H, N-CH3, N- CH2CH3, N-CH(CH3)2, N-C02t-Bu, N-Aryl, N-Heteroaryl, N-Heterocyclyl steht. A 5 represents S (sulfur), O (oxygen) or the groupings NH, N-CH 3 , N-CH 2 CH 3 , N-CH (CH 3 ) 2 , N-CO 2 t-Bu, N-aryl, N-heteroaryl, N-heterocyclyl is.
R19, R20, R23 und R24 unabhängig voneinander für Wasserstoff, (Ci-C7)-Alkyl, Halogen, (C3-C7)-Cycloalkyl, Aryl, Heteroaryl, Heterocyclyl, (C2-C7)- Alkenyl, (C2-C7)-Alkenyl-(Ci-C7)-alkyl, Aryl-(Ci-C7)-alkyl, (Ci-C7)-Alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkyl, Hydroxy, (CrC7)-Haloalkyl, (Ci-C7)-Haloalkylthio stehen, R19 und R23 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R 19 , R 20 , R 23 and R 24 independently of one another represent hydrogen, (C 1 -C 7) -alkyl, halogen, (C 3 -C 7) -cycloalkyl, aryl, heteroaryl, heterocyclyl, (C 2 -C 7) -alkenyl, (C 2 -C 4) -alkyl -C 7) alkenyl (Ci-C7) alkyl, aryl (Ci-C7) alkyl, (Ci-C7) alkoxy, (Ci-C7) alkoxy (Ci-C7) alkoxy, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -alkyl, hydroxy, (C 1 -C 7 ) -haloalkyl, (C 1 -C 7 ) -haloalkylthio, R 19 and R 23 with the atoms to which they are attached form a completely saturated or partially saturated, optionally further substituted 5 to 7-membered ring,
A6, A7 gleich oder verschieden sind und unabhängig voneinander für O A 6 , A 7 are the same or different and are each independently O.
(Sauerstoff), S (Schwefel), N-H, N-OCH3, N-CH3 oder die Gruppierung CR21 R22 stehen, wobei jedoch in keinem Fall zwei N-, O- oder S-Atome benachbart sind, und wobei R21 und R22 in der Gruppierung CR21 R22 jeweils gleiche oder verschiedene Bedeutungen gemäß der (Oxygen), S (sulfur), NH, N-OCH 3 , N-CH 3 or the group CR 21 R 22 are, but in any case, two N, O or S atoms are adjacent, and wherein R 21 and R 22 in the group CR 21 R 22 each have the same or different meanings according to the
nachstehenden Definition haben und  have the following definition and
R21 und R22 unabhängig voneinander für Wasserstoff, Halogen, (Ci-C7)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (C3-C7)-Cycloalkyl, (C2-C7)-Alkenyl, R 21 and R 22 independently of one another represent hydrogen, halogen, (C 1 -C 7 ) -alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 7 ) -cycloalkyl, (C 2 -C 7 ) -alkenyl,
(Ci-C7)-Alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkyl, Aryloxy-(Ci-C7)-alkyl, (d-C7)-Haloalkoxy, (Ci-C7)-Haloalkyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-alkyl, (Ci-C7)-Alkoxy-(d-C7)-haloalkyl, (Ci-C7)-Haloalkoxy-(CrC7)-haloalkyl, (Ci-C7)-Alkylthio, (d-C7)-Haloalkylthio, (Ci-C7)-Alkylthio-(CrC7)-alkyl, Hydroxycarbonyl, (Ci-C7)-Alkoxycarbonyl, (C3-C7)-Cycloalkoxycarbonyl, (C3-C7)-Cycloalkyl-(Ci-C7)-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C7)- alkoxycarbonyl , (C2-C7)-Alkenyloxycarbonyl , (C2-C7)-Al ki nyloxycarbonyl , Aminocarbonyl, (d-C7)-Alkylaminocarbonyl, Bis[(d-C7)- alkyljaminocarbonyl, (Ci-C7)-Alkyl[(Ci-C7)-Alkyl]aminocarbonyl, (C1-C7)- Alkyl[(d-C7)-Alkoxy]aminocarbonyl, (C2-C7)-Alkenylaminocarbonyl, (C3-C7)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C7)- alkylaminocarbonyl, Amino, (CrC7)-Alkylamino, (C3-C7)-Cycloalkylamino, Bis-[(Ci-C7)-Alkyl]amino stehen, (Ci-C7) alkoxy, (Ci-C7) alkoxy (Ci-C7) alkyl, aryloxy (Ci-C7) alkyl, (dC 7) haloalkoxy, (Ci-C 7 ) -Haloalkyl, (Ci-C 7 ) -haloalkoxy- (Ci-C 7 ) -alkyl, (Ci-C 7 ) -alkoxy- (dC 7 ) -haloalkyl, (Ci-C 7 ) -haloalkoxy- (CrC 7 ) haloalkyl, (C 1 -C 7 ) -alkylthio, (C 1 -C 4 ) -haloalkylthio, (C 1 -C 7 ) -alkylthio (C 1 -C 7 ) -alkyl, hydroxycarbonyl, (C 1 -C 7 ) -alkoxycarbonyl, (C 3 -C 4 ) -alkylthio, C 7 ) -cycloalkoxycarbonyl, (C 3 -C 7 ) -cycloalkyl- (C 1 -C 7 ) -alkoxycarbonyl, aryloxycarbonyl, aryl- (C 1 -C 7 ) -alkoxycarbonyl, (C 2 -C 7 ) -alkenyloxycarbonyl, (C 2 -C 7) Al ki nyloxycarbonyl, aminocarbonyl, (dC 7) alkylaminocarbonyl, bis [(dC 7) - alkyljaminocarbonyl, (Ci-C 7) alkyl [(Ci-C 7) alkyl] aminocarbonyl, (C1-C7) - alkyl [(dC 7) -alkoxy] aminocarbonyl, (C2-C7) -Alkenylaminocarbonyl, (C 3 -C 7) cycloalkylaminocarbonyl, arylaminocarbonyl, aryl (Ci-C7) - alkylaminocarbonyl, amino, (CrC 7) Alkylamino, (C 3 -C 7 ) -cycloalkylamino, bis - [(C 1 -C 7 ) -alkyl] -amino,
R25, R26, R28 und R29 unabhängig voneinander für Wasserstoff, (Ci-C7)-Alkyl, Halogen, (C3-C7)-Cycloalkyl, Aryl, Heteroaryl, Heterocyclyl, (C2-C7)- Alkenyl, Aryl-(d-C7)-alkyl, (Ci-C7)-Alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkoxy, (Ci-C7)-Alkoxy-(CrC7)-alkyl, (d-C7)-Haloalkyl stehen, A8 für O (Sauerstoff), S (Schwefel), N-H, N-CH3, N-OCH3 oder die Gruppierung CHR27 steht und wobei R27 in der Gruppierung CHR27 die Bedeutung gemäß der nachstehenden Definition hat, R 25 , R 26 , R 28 and R 29 independently of one another are hydrogen, (C 1 -C 7 ) -alkyl, halogen, (C 3 -C 7 ) -cycloalkyl, aryl, heteroaryl, heterocyclyl, (C 2 -C 7 ) -alkenyl, Aryl- (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -alkoxy, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -alkoxy, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) - alkyl, (dC 7 ) -haloalkyl, A 8 is O (oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the moiety CHR 27 , and wherein R 27 in the moiety CHR 27 has the meaning as defined below,
R27 für Wasserstoff, Halogen, (Ci-C7)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, R 27 represents hydrogen, halogen, (C 1 -C 7 ) -alkyl, aryl, heteroaryl, heterocyclyl,
(C3-C7)-Cycloalkyl, (C2-C7)-Alkenyl, (Ci-C7)-Alkoxy, (Ci-C7)-Alkoxy- (Ci-C7)-alkyl, Aryloxy-(Ci-C7)-alkyl, (Ci-C7)-Haloalkoxy, (Ci-C7)-Haloalkyl, (Ci-C7)-Alkoxy-(CrC7)-haloalkyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-haloalkyl, (Ci-C7)-Alkylthio, (Ci-C7)-Haloalkylthio, (Ci-C7)-Alkylthio-(Ci-C7)-alkyl, Hydroxycarbonyl, (Ci-C7)-Alkoxycarbonyl, (C3-C7)-Cycloalkoxycarbonyl, Aryl-(CrC7)-alkoxycarbonyl, (C2-C7)-Alkenyloxycarbonyl, (C2-C7)- Alkinyloxycarbonyl, Aminocarbonyl, (CrC7)-Alkylaminocarbonyl, (C 3 -C 7) cycloalkyl, (C 2 -C 7) alkenyl, (Ci-C7) alkoxy, (Ci-C7) alkoxy (Ci-C7) alkyl, aryloxy ( C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -haloalkoxy, (C 1 -C 7 ) -haloalkyl, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -haloalkyl, (C 1 -C 7 ) -haloalkoxy - (C 1 -C 7 ) -haloalkyl, (C 1 -C 7 ) -alkylthio, (C 1 -C 7 ) -haloalkylthio, (C 1 -C 7 ) -alkylthio (C 1 -C 7 ) -alkyl, hydroxycarbonyl, (Ci -C 7) alkoxycarbonyl, (C3-C 7) cycloalkoxycarbonyl, aryl (-C 7) -alkoxycarbonyl, (C2-C7) alkenyloxycarbonyl, (C2-C7) - alkynyloxycarbonyl, aminocarbonyl, (CrC 7) - alkylaminocarbonyl,
Bis[(Ci-C7)-alkyl]aminocarbonyl, (Ci-C7)-Alkyl[(d-C7)- Alkyl]aminocarbonyl, (Ci-C7)-Alkyl[(CrC7)-Alkoxy]aminocarbonyl, (C2-C7)-Alkenylaminocarbonyl, (C3-C7)-Cycloalkylaminocarbonyl, Bis [(Ci-C 7 ) -alkyl] aminocarbonyl, (Ci-C 7 ) -alkyl [(dC 7 ) -alkyl] aminocarbonyl, (Ci-C 7 ) -alkyl [(CrC 7 ) -alkoxy] aminocarbonyl, ( C2-C7) -Alkenylaminocarbonyl, (C3-C 7) cycloalkylaminocarbonyl,
Arylaminocarbonyl, Aryl-(Ci-C )-alkylaminocarbonyl, Amino, (Ci-C7)- Alkylamino, (C3-C7)-Cycloalkylamino, Bis-[(CrC7)-Alkyl]amino steht, Arylaminocarbonyl, aryl (Ci-C) alkylaminocarbonyl, amino, (Ci-C7) - alkylamino, (C3-C7) cycloalkylamino, bis - [(-C 7) alkyl] amino is,
R30, R31 , R32, R34, R35 und R36 unabhängig voneinander für Wasserstoff, (Ci-C7)- Alkyl, Halogen, (C3-C7)-Cycloalkyl, Aryl, Heteroaryl, Heterocyclyl, (C2-C7)- Alkenyl, (Ci-C7)-Alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkoxy, (d-C7)-Alkoxy- (Ci-C7)-alkyl, (Ci-C7)-Haloalkyl, (Ci-C7)-Alkylthio, (d-C7)-Haloalkylthio stehen, R 30, R 31, R 32, R 34, R 35 and R 36 are independently hydrogen, (Ci-C7) - alkyl, halogen, (C3-C 7) cycloalkyl, aryl, heteroaryl, heterocyclyl, (C2 -C 7) - alkenyl, (C 1 -C 7 ) -alkoxy, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -alkoxy, (C 1 -C 4 ) -alkoxy- (C 1 -C 7 ) -alkyl, ( Ci-C 7 ) -haloalkyl, (Ci-C 7 ) -alkylthio, (dC 7 ) -haloalkylthio,
A9 für O (Sauerstoff), S (Schwefel), N-H, N-CH3, N-OCH3 oder die Gruppierung CHR33 steht und wobei R33 in der Gruppierung CHR33 die Bedeutung gemäß der nachstehenden Definition hat und A 9 is O (oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the group CHR 33 , and wherein R 33 in the group CHR 33 has the meaning as defined below and
R33 für Wasserstoff, Halogen, (Ci-C7)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, R 33 is hydrogen, halogen, (C 1 -C 7 ) -alkyl, aryl, heteroaryl, heterocyclyl,
(C3-C7)-Cycloalkyl, (C2-C7)-Alkenyl, (Ci-C7)-Alkoxy, (Ci-C7)-Alkoxy- (Ci-C7)-alkyl, Aryloxy-(Ci-C7)-alkyl, (Ci-C7)-Haloalkoxy, (Ci-C7)-Haloalkyl, (d-C7)-Alkylthio, (d-C7)-Haloalkylthio, Hydroxycarbonyl, (C1-C7)- Alkoxycarbonyl, (C3-C7)-Cycloalkoxycarbonyl, Aryl-(Ci-C7)- alkoxycarbonyl , (C2-C7)-Alkenyloxycarbonyl , (C2-C7)-Al ki nyloxycarbonyl , Aminocarbonyl, (Ci-C7)-Alkylaminocarbonyl, Bis[(Ci-C7)- alkyljaminocarbonyl, (Ci-C7)-Alkyl[(CrC7)-Alkyl]aminocarbonyl, (C1-C7)- Alkyl[(CrC7)-Alkoxy]aminocarbonyl, (C2-C7)-Alkenylaminocarbonyl, (C 3 -C 7) cycloalkyl, (C 2 -C 7) alkenyl, (Ci-C7) alkoxy, (Ci-C7) alkoxy (Ci-C7) alkyl, aryloxy ( Ci-C 7) alkyl, (Ci-C7) haloalkoxy, (Ci-C7) haloalkyl, (dC 7) alkylthio, (dC 7) haloalkylthio, hydroxycarbonyl, (C1-C7) - alkoxycarbonyl, (C3-C 7) cycloalkoxycarbonyl, aryl (Ci-C7) - alkoxycarbonyl, (C 2 -C 7) alkenyloxycarbonyl, (C 2 -C 7) Al ki nyloxycarbonyl, Aminocarbonyl, (C 1 -C 7) -alkylaminocarbonyl, bis [(C 1 -C 7) -alkylaminocarbonyl, (C 1 -C 7) -alkyl [(C 1 -C 7) -alkyl] aminocarbonyl, (C 1 -C 7) -alkyl [(C 1 -C 7) -alkoxy] aminocarbonyl, (C 2 -C 7) -alkenylaminocarbonyl,
(C3-C7)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(d-C7)- alkylaminocarbonyl, Amino, (CrC7)-Alkylamino, (C3-C7)-Cycloalkylamino, Bis-[(Ci-C7)-Alkyl]amino steht, (C 3 -C 7) cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 7) -alkylaminocarbonyl, amino, (C 1 -C 7) -alkylamino, (C 3 -C 7 ) -cycloalkylamino, bis- [(C 1 -C 7 ) -alkyl] -amino .
R37 für (Ci-C7)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (C3-C7)-Cycloalkyl, (C2-C7)- Alkenyl, (Ci-C7)-Alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkyl, Aryloxy-(Ci-C7)- alkyl, (Ci-C7)-Alkoxycarbonyl, (C3-C7)- Cycloalkoxycarbonyl, Aryl-(Ci-C7)- alkoxycarbonyl , (C2-C7)-Alkenyloxycarbonyl , (C2-C7)-Al ki nyloxycarbonyl , (CrC7)-Alkylcarbonyl, (C3-C7)-Cycloalkylcarbonyl, Arylcarbonyl, R 37 is (C 1 -C 7 ) -alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 7 ) -cycloalkyl, (C 2 -C 7 ) -alkenyl, (C 1 -C 7 ) -alkoxy, (C 1 -C 7 ) Alkoxy- (C 1 -C 7 ) -alkyl, aryloxy- (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -alkoxycarbonyl, (C 3 -C 7 ) -cycloalkoxycarbonyl, aryl- (C 1 -C 7 ) -alkoxycarbonyl, ( C 2 -C 7) -alkenyloxycarbonyl, (C 2 -C 7) -alkyloxycarbonyl, (C 1 -C 7) -alkylcarbonyl, (C 3 -C 7) -cycloalkylcarbonyl, arylcarbonyl,
Heteroarylcarbonyl steht.  Heteroarylcarbonyl stands.
Behandlung von Pflanzen, umfassend die Applikation einer zur Steigerung der Widerstandsfähigkeit von Pflanzen gegenüber abioti sehen Stressfaktoren wirksamen, nicht-toxischen Menge einer oder mehrerer der Verbindungen der Formel (I), oder jeweils deren Salze gemäß einem der Ansprüche 1 bis 3. Treatment of plants, comprising the application of a non-toxic amount of one or more of the compounds of the formula (I) which is effective for increasing the resistance of plants to abiotic stress factors, or in each case their salts according to one of Claims 1 to 3.
Behandlung gemäß Anspruch 4, wobei die abiotischen Stressbedingungen einer oder mehrerer Bedingungen ausgewählt aus der Gruppe bestehend aus Dürre, Kältestress, Hitzestress, Trockenstress, osmotischem Stress, Staunässe, erhöhtem Bodensalzgehalt, erhöhtem Ausgesetztsein an Mineralien, The treatment of claim 4, wherein the abiotic stress conditions include one or more conditions selected from the group consisting of drought, cold stress, heat stress, drought stress, osmotic stress, waterlogging, increased soil salt content, increased exposure to minerals,
Ozonbedingungen, Starklichtbedingungen, beschränkter Verfügbarkeit von Stickstoff n ä h rstoff e n und beschränkter Verfügbarkeit von Phosphornährstoffen entsprechen. Ozone conditions, high light conditions, limited availability of nitrogen and limited availability of phosphorus nutrients.
Verwendung einer oder mehrerer Verbindungen der Formel (I), oder jeweils deren Salze gemäß einem der Ansprüche 1 bis 3 in der Sprühapplikation auf Pflanzen und Pflanzenteilen in Kombinationen mit einem oder mehrer Use of one or more compounds of the formula (I), or in each case their salts according to one of Claims 1 to 3, in the spray application to plants and plant parts in combinations with one or more
Wirkstoffen ausgewählt aud der Gruppe der Insektizide, Lockstoffe, Akarizide, Fungizide, Nematizide, Herbizide, wachstumsregulatorische Stoffe, Safener, die Pflanzen reife beeinflussende Stoffe und Bakterizide. Active ingredients selected from the group of insecticides, attractants, acaricides, fungicides, nematicides, herbicides, growth regulators, safeners, the plants mature affecting substances and bactericides.
7. Verwendung einer oder mehrerer Verbindungen der Formel (I), oder jeweils deren Salze gemäß einem der Ansprüche 1 bis 3 in der Sprühapplikation auf Pflanzen und Pflanzenteilen in Kombinationen mit Düngemitteln. 7. Use of one or more compounds of the formula (I), or in each case their salts according to one of claims 1 to 3 in the spray application to plants and plant parts in combinations with fertilizers.
Verwendung einer oder mehrerer Verbindungen der Formel (I), oder jeweils deren Salze gemäß einem der Ansprüche 1 bis 3 zur Applikation auf gentechnisch veränderten Sorten, deren Saatgut, oder auf Anbauflächen auf denen diese Sorten wachsen. Use of one or more compounds of the formula (I), or in each case their salts according to one of Claims 1 to 3, for application to genetically modified varieties, their seeds, or to cultivated areas on which these varieties grow.
Verwendung von Sprühlösungen, die eine oder mehrere der Verbindungen der Formel (I), oder jeweils deren Salze gemäß einem der Ansprüche 1 bis 3 enthalten, zur Steigerung der Widerstandsfähigkeit von Pflanzen gegenüber abiotischen Stressfaktoren. 10. Verfahren zur Erhöhung der Stresstoleranz bei Pflanzen ausgewählt aus der Gruppe der Nutzpflanzen, Zierpflanzen, Rasenarten, oder Bäumen, dadurch gekennzeichnet, dass die Applikation einer ausreichenden, nicht-toxischen Menge einer oder mehrere Verbindungen der Formel (I), oder jeweils deren Salze gemäß einem der Ansprüche 1 bis 3 auf die Fläche, wo die Use of spray solutions which comprise one or more of the compounds of the formula (I), or in each case their salts according to one of Claims 1 to 3, for increasing the resistance of plants to abiotic stress factors. 10. A method for increasing the stress tolerance in plants selected from the group of crops, ornamental plants, lawn species, or trees, characterized in that the application of a sufficient, non-toxic amount of one or more compounds of formula (I), or in each case their salts according to one of claims 1 to 3 on the area where the
entsprechende Wirkung gewünscht wird, umfassend die Anwendung auf die corresponding effect is desired, comprising the application to the
Pflanzen, deren Saatgut oder auf die Fläche auf der die Pflanzen wachsen, erfolgt. Plants whose seeds or on the surface on which the plants grow takes place.
Verfahren gemäß Anspruch 10, wobei die Widerstandsfähigkeit der so behandelten Pflanzen gegenüber abiotischem Stress gegenüber nicht behandelten Pflanzen unter ansonsten gleichen physiologischen Bedingunge um mindestens 3% erhöht ist. A method according to claim 10, wherein the resistance of the thus treated plants to abiotic stress is increased by at least 3% over non-treated plants under otherwise identical physiological conditions.
12. Substituierte 1 -(Arylethiny!)-, 1 -(Heteroarylethinyl)-, l-(Heterocyclylethinyl)- und 1 -(Cyloalkenylethinyl)-bicycloalkanole der allgemeinen Formel (I) oder deren Salze 12. Substituted 1- (arylethiny!) -, 1- (heteroarylethynyl) -, 1- (heterocyclylethynyl) - and 1- (cycloalkenylethynyl) bicycloalkanols of the general formula (I) or salts thereof
worin worin in which
[X-Y] für die Grupp [X-Y] for the group
[x-YT steht, für die Gruppierungen Q-1 bis Q-6 [x-YT stands for the groupings Q-1 to Q-6
Q-1 Q-2 Q-3  Q-1 Q-2 Q-3
Q-4 , Q-5 und Q-6 steht, wobei R13, R14, R15, R16, R17, R18, R19, R20, R23, R24, R25, R26, R28, R29, R30, R31, R32, R34, R35 und R36 sowie A1 bis A9 jeweils die Bedeutung gemäß der nachstehenden Definitionen haben und wobei der Pfeil für eine Bindung zur jeweiligen Gruppierung C-R6 in der allgemeinen Formel (I) steht, R1 für (Ci-C7)-Alkyl, (C3-C7)-Cycloalkyl, (C4-C7)-Cycloalkenyl, (C2-C7)-Q-4, Q-5 and Q-6, wherein R 13 , R 14 , R 15 , R 16 , R 17 , R 18 , R 19 , R 20 , R 23 , R 24 , R 25 , R 26 , R 28 , R 29 , R 30 , R 31 , R 32 , R 34 , R 35 and R 36 and A 1 to A 9 are each as defined below and wherein the arrow indicates a bond to the respective grouping CR 6 in the general formula (I) stands, R 1 is (C 1 -C 7 ) -alkyl, (C 3 -C 7 ) -cycloalkyl, (C 4 -C 7 ) -cycloalkenyl, (C 2 -C 7 ) -
Alkenyl, (C2-C7)-Alkinyl, (C2-C7)-Alkenyi-(Ci-C7)-alkyl, (C2-C7)-Alkinyl- (Ci-C7)-alkyl, (Ci-C7)-Alkoxy-(Ci-C7)-alkyl, Hydroxy-(d-C7)-alkyl, (C1-C7)- Haloalkyl, (C2-C7)-Haloalkenyl, (C2-C7)-Haloalkinyl, (Ci-C7)-Haloalkoxy- (CrC7)-alkyl, (Ci-C7)-Alkoxy-(CrC7)-haloalkyl, (Ci-C7)-Haloalkoxy- (Ci-C7)-haloalkyl, (Ci-C7)-Alkylthio-(Ci-C7)-alkyl, (Ci-C7)-Haloalkylthio- (Ci-C7)-alkyl steht, Alkenyl, (C 2 -C 7) -alkynyl, (C 2 -C 7) -Alkenyi- (Ci-C7) alkyl, (C 2 -C 7) alkynyl (Ci-C7) alkyl, (Ci-C7) alkoxy (Ci-C7) alkyl, hydroxy (dC 7) alkyl, (C1-C7) - haloalkyl, (C 2 -C 7) haloalkenyl, (C 2 -C 7 ) -haloalkynyl, (Ci-C 7 ) -haloalkoxy- (CrC 7 ) -alkyl, (Ci-C 7 ) -alkoxy- (CrC 7 ) -haloalkyl, (Ci-C 7 ) -haloalkoxy- (Ci-C 7 ) -haloalkyl, (C 1 -C 7 ) -alkylthio (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -haloalkylthio (C 1 -C 7 ) -alkyl,
R2, R3 und R4 unabhängig voneinander für Wasserstoff, Halogen, (Ci-C7)- Alkyl, (C3-C7)-Cycloalkyl, (C4-C7)-Cycloalkenyl, (C2-C7)-Alkenyl, (C2-C7)-Alkinyl, (C2-C7)-Alkenyl-(d-C7)-alkyl, (C2-C7)-Alkinyl-(d-C7)-alkyl, (C1-C7)- Alkoxy-(d-C7)-alkyl, Hydroxy-(Ci-C7)-alkyl, (d-C7)-Haloalkyl, (C2-C7)- Haloalkenyl, (C2-C7)-Haloalkinyl, (Ci-C7)-Haloalkoxy-(CrC7)-alkyl, (CrC7)-Alkoxy-(Ci-C7)-haloalkyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-haloalkyl, (Ci-C7)-Alkylthio-(Ci-C7)-alkyl, (Ci-C7)-Haloalkylthio-(Ci-C7)-alkyl stehen, R 2, R 3 and R 4 are independently hydrogen, halogen, (Ci-C7) - alkyl, (C 3 -C 7) cycloalkyl, (C 4 -C 7) -cycloalkenyl, (C 2 -C 7 ) alkenyl, (C 2 -C 7) -alkynyl, (C 2 -C 7) alkenyl (dC 7) alkyl, (C 2 -C 7) alkynyl (dC 7) alkyl, (C1 C7) - alkoxy (dC 7) alkyl, hydroxy (Ci-C7) alkyl, (dC 7) -haloalkyl, (C2-C7) - haloalkenyl, (C 2 -C 7) haloalkynyl, ( C 1 -C 7 ) -haloalkoxy- (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -haloalkyl, (C 1 -C 7 ) -haloalkoxy- (C 1 -C 7 ) -haloalkyl, ( C 1 -C 4 ) -alkylthio (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -haloalkylthio (C 1 -C 7 ) -alkyl,
R5 für Hydroxy, (CrC7)-Alkoxy, Aryloxy, (C3-C7)-Cycloalkyloxy, (C2-C7)- Alkenyloxy, (C2-C7)-Alkenyl-(Ci-C7)-alkyloxy, (Ci-C7)-Alkoxy-(Ci-C7)- alkyloxy, (Ci-C7)-Alkylcarbonyloxy, Arylcarbonyloxy, R 5 is hydroxy, (C 1 -C 7 ) -alkoxy, aryloxy, (C 3 -C 7 ) -cycloalkyloxy, (C 2 -C 7 ) -alkenyloxy, (C 2 -C 7 ) -alkenyl- (C 1 -C 7 ) -alkyloxy , (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -alkyloxy, (C 1 -C 7 ) -alkylcarbonyloxy, arylcarbonyloxy,
Heteroarylcarbonyloxy, (C3-C7)-Cycloalkylcarbonyloxy, (C1-C7)- Alkoxycarbonyloxy, (C2-C7)-Alkenyloxycarbonyloxy, Aryloxy-(d-C7)- alkyloxy, Aryl-(Ci-C7)-alkyloxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkoxy-(d-C7)- alkyloxy, (Ci-C7)-Alkylthio-(CrC7)-alkyloxy, T s[(CrC7)-alkyl]silyloxy, (Ci-C7)-Alkyl-Bis[(Ci-C7)-alkyl]silyloxy, (CrC7)-Alkyl-bis(Aryl)silyloxy, Aryl-bis[(Ci-C7)— aikyijsilyloxy, Cycloalkyl-bis[(Ci-C7)-alkyl]silyloxy, Halo- bis[(CrC7)-alkyl]silyloxy, Tris[(Ci-C7)-alkyl]silyl-(Ci-C7)-alkoxy-(Ci-C7)- alkyloxy, steht, Heteroarylcarbonyloxy, (C3-C 7) cycloalkylcarbonyloxy, (C1-C7) - alkoxycarbonyloxy, (C 2 -C 7) -Alkenyloxycarbonyloxy, aryloxy (dC 7) - alkyloxy, aryl- (Ci-C7) alkyloxy, ( Ci-C7) alkoxy (Ci-C7) alkoxy (dC 7) - alkyloxy, (Ci-C7) -alkylthio (-C 7) alkyloxy, T s [(-C 7) alkyl] silyloxy, (C 1 -C 7 ) -alkyl-bis [(C 1 -C 7 ) -alkyl] silyloxy, (C 1 -C 7 ) -alkyl-bis (aryl) silyloxy, aryl-bis [(C 1 -C 7 ) -alkyl) silyloxy, Cycloalkyl-bis [(C 1 -C 7 ) -alkyl] silyloxy, halo-bis [(C 1 -C 7 ) -alkyl] silyloxy, tris [(C 1 -C 7 ) -alkyl] silyl (C 1 -C 7 ) -alkoxy (C 1 -C 7 ) -alkyloxy,
R6 für (Ci-C7)-Alkylsulfonylaminocarbonyl, (C3-C7)-R 6 is (C 1 -C 7 ) -alkylsulfonylaminocarbonyl, (C 3 -C 7 ) -
Cycloalkylsulfonylaminocarbonyl, Hydroxycarbonyl, (C1-C7)- Alkoxycarbonyl, (C3-C7)-Cycloalkoxycarbonyl, (C3-C7)-Cycloalkyl-(Ci-C7)- alkoxycarbonyl, Aryloxycarbonyl, Aryl-(CrC7)-alkoxycarbonyl, (C2-C7)- Alkenyloxycarbonyl, (C2-C7)-Alkinyloxycarbonyl, (C1-C7)- Haloalkyloxycarbonyl, (Ci-C7)-Alkoxy-(Ci-C7)-alkoxycarbonyl, (C2-C7)- Alkenyloxy-(Ci-C7)-alkoxycarbonyl, (Ci-C7)-Alkylamino-(Ci-C-7)- alkoxycarbonyl, Tris[(CrC7)-alkyl]silyloxy-(Ci-C7)-aikoxycarbonyl, Bis[(Ci-C7)-Alkyl]amino-(Ci-C7)-alkoxycarbonyl, (Ci-C7)-Alkyl[(Ci-C7)- alkyl]amino-(CrC7)-alkoxycarbonyl, Cyano-(d-C7)-alkoxycarbonyl, Heterocyclyl-N-(CrC7)-alkoxycarbonyl, Heteroaryloxycarbonyl, Cycloalkylsulfonylaminocarbonyl, hydroxycarbonyl, (C 1 -C 7 ) -alkoxycarbonyl, (C 3 -C 7 ) -cycloalkoxycarbonyl, (C 3 -C 7 ) -cycloalkyl- (C 1 -C 7 ) -alkoxycarbonyl, aryloxycarbonyl, aryl- (C 1 -C 7 ) -alkoxycarbonyl, (C 2 -C 7) - alkenyloxycarbonyl, (C 2 -C 7) -alkynyloxycarbonyl, (C1-C7) - Haloalkyloxycarbonyl, (Ci-C7) alkoxy (Ci-C7) -alkoxycarbonyl, (C 2 - C 7 ) - Alkenyloxy (C 1 -C 7) alkoxycarbonyl, (C 1 -C 7) alkylamino (C 1 -C 7) alkoxycarbonyl, tris [(C 1 -C 7) alkyl] silyloxy (C 1 -C 7) -aikoxycarbonyl, bis [(Ci -C 7) alkyl] amino- (Ci-C 7) alkoxycarbonyl, (Ci-C 7) alkyl [(Ci-C7) - alkyl] amino- (CRC7) -alkoxycarbonyl, cyano, (d-C7 ) -alkoxycarbonyl, heterocyclyl-N- (C 1 -C 7) -alkoxycarbonyl, heteroaryloxycarbonyl,
Heteroaryl-(Ci-C7)-alkoxycarbonyl, Heterocyclyl-(Ci-C7)-alkoxycarbonyl, Heterocyclyloxycarbonyl, (C2-C7)-Alkenyl-(d-C7)-alkoxycarbonyl, (C2-C7)-Alkinyl-(CrC7)-alkoxycarbonyl, Aryl-(C2-C7)-alkinyloxycarbonyl, Aryl-(C2-C7)-alkenyloxycarbonyl, Aminocarbonyl, (C1-C7)- Alkylaminocarbonyl, Bis[(Ci-C7)-alkyl]aminocarbonyl, (C1-C7)- Alkyl[(Ci-C7)-Alkyl]aminocarbonyl, (Ci-C7)-Alkyl[(Ci-C7)- Alkoxy]aminocarbonyl, (C2-C7)-Alkenylaminocarbonyl, (C3-C7)- Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C7)- alkylaminocarbonyl, Heteroaryl-(CrC7)-alkyiaminocarbonyl, Cyano- (Ci-C7)-alkylaminocarbonyl, (Ci-C7)-HaloalkylaminocarbonyL (C2-C7)- Alkinyl-(CrC7)-alkylaminocarbonyl, (C1-C7)- Alkoxycarbonylaminocarbonyl, Aryl-(d-C7)- alkoxycarbonylaminocarbonyl, Hydroxycarbonyl-(Ci-C7)-alkyL (C1-C7)- Alkoxycarbonyl-(Ci-C7)-alkyl, (C3-C7)-Cycloalkoxycarbonyl-(Ci-C7)-alkyl, (C3-C7)-Cycloalkyl-(Ci-C7)-alkoxycarbonyl-(Ci-C7)-alkyl, (C2-C7)- Alkenyloxycarbonyl-(d-C7)-alkyl, Aryl-(Ci-C7)-alkoxycarbonyl-(CrC7)- alkyl, (Ci-C7)-Alkylaminocarbonyl-(Ci-C7)-alkyl, Aminocarbonyl-(Ci-C7)- alkyl, Bis[(Ci-C7)-alkyl]aminocarbonyl-(Ci-C7)-alkyl, (C3-C7)- Cycloalkylaminocarbonyl-(CrC7)-alkyl, Aryl-(Ci-C7)-alkylaminocarbonyl- (Ci-C7)-alkyl, Heteroaryl-(Ci-C7)-alkylaminocarbonyl-(CrC7)-alkyL Cyano-(Ci-C7)-alkylaminocarbonyl-(CrC7)-alkyl, (C1-C7)- Haloalkylaminocarbonyl-(Ci-C7)-alkyL (C2-C7)-Alkinyl-(Ci-C7)- alkylaminocarbonyl-(Ci-C7)-alkyl, (C3-C7)-Cycloalky!-(Ci-C7)- alkylaminocarbonyl-(Ci-C7)-alkyl, (Ci-C7)-Alkoxycarbonylaminocarbonyl- (Ci-C7)-alkyl, Aryl-(Ci-C7)-alkoxycarbonylaminocarbonyl-(CrC7)-alkyl, (Ci-C7)-Alkoxycarbonyl-(Ci-C7)-alkylaminocarbonyl, Hydroxycarbonyl- (Ci-C7)-alkylaminocarbonyl, Aryl-(Ci-C7)-alkoxycarbonyl-(d-C7)- alkylaminocarbonyl, Aminocarbonyl-(Ci-C7)-alkylaminocarbonyl, (C1-C7)- Alkylaminocarbonyl-(Ci-C7)-alkylaminocarbonyl. (C3-C7)-Cycloalkylaminocarbonyl-(Ci-C7)-alkylaminocarbonyl, (C3-C7)- Cycloalkyl-(Ci-C7)-alkylaminocarbonyl, (C3-C7)-Cycloalkyl-(Ci-C7)- alkylaminocarbonyl-(Ci-C7)-alkyl, (C3-C7)-Cycloalkyl-(Ci-C7)- alkylaminocarbonyi-(Ci-C7)-alkylaminocarbonyl, (C2-C7)-Alkenyl-(d-C7)- alkylaminocarbonyl, (C2-C7)-Alkenylaminocarbonyl-(Ci-C7)-alkyl, (C2-C7)- Alkenyl-(Ci-C7)-alkylaminocarbonyl-(Ci-C7)-alkyL (d-C7)-Alkylcarbonyl, (C3-C7)-Cycloalkylcarbonyl, Arylcarbonyl, Formyl, Hydroxyiminomethyl, Aminoiminomethyl, (Ci-C7)-Alkoxyiminomethyl, (C1-C7)- Alkylaminoiminomethyl, Bis[(Ci-C7)-alkyl]aminoiminomethyl, (C3-C7)- Cycloalkoxyiminomethyl, (C;?-C7)-Cycloalkyl-(Ci-C7)-alkoximinomethyl, Aryloximinomethyi, Aryl-(CrC7)-alkoxyiminomethyl, Aryl-(d-C7)- alkylaminoiminomethyl, (C2-C7)-Alkenyloxyiminomethyl, Heteroaryl- (C 1 -C 7) -alkoxycarbonyl, heterocyclyl- (C 1 -C 7) -alkoxycarbonyl, heterocyclyloxycarbonyl, (C 2 -C 7) -alkenyl- (C 1 -C 7) -alkoxycarbonyl, (C 2 -C 7) -alkynyl- (C 1 -C 7) - alkoxycarbonyl, aryl- (C 2 -C 7) -alkynyloxycarbonyl, aryl- (C 2 -C 7) -alkenyloxycarbonyl, aminocarbonyl, (C 1 -C 7) -alkylaminocarbonyl, bis [(C 1 -C 7) -alkyl] -aminocarbonyl, (C 1 -C 7) - alkyl [(Ci-C 7) alkyl] aminocarbonyl, (Ci-C 7) alkyl [(Ci-C7) - alkoxy] aminocarbonyl, (C2-C7) -Alkenylaminocarbonyl, (C3-C7) - cycloalkylaminocarbonyl, arylaminocarbonyl , Aryl- (C 1 -C 7) -alkylaminocarbonyl, heteroaryl- (C 1 -C 7) -alkylaminocarbonyl, cyano- (C 1 -C 7) -alkylaminocarbonyl, (C 1 -C 7) -haloalkylaminocarbonyL (C 2 -C 7) -alkynyl- (C 1 -C 7) -alkylaminocarbonyl, (C 1 -C 7) alkoxycarbonylaminocarbonyl, aryl- (C 1 -C 7) alkoxycarbonylaminocarbonyl, hydroxycarbonyl- (C 1 -C 7) -alkyL (C 1 -C 7) -alkoxycarbonyl- (C 1 -C 7) -alkyl, (C 3 -C 7) -cycloalkoxycarbonyl (C 1 -C 7) -alkyl, (C 3 -C 7) -cycloalkyl- (C 1 -C 7) -alkoxycarbonyl- (C 1 -C 7) -alkyl, (C 2 -C 7) -alkenyloxycarbonyl- (C 1 -C 7) -alkyl, (aryl- (Ci-C7) alkoxycarbonyl C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -alkylaminocarbonyl- (C 1 -C 7 ) -alkyl, aminocarbonyl- (C 1 -C 7 ) -alkyl, bis [(C 1 -C 7 ) -alkyl] aminocarbonyl- (C 1 -C 7 ) - alkyl, (C 3 -C 7) -cycloalkylaminocarbonyl- (C 1 -C 7) -alkyl, aryl- (C 1 -C 7) -alkylaminocarbonyl- (C 1 -C 7) -alkyl, heteroaryl- (C 1 -C 7) -alkylaminocarbonyl- (C 1 -C 7) -alkyL cyano (C 1 -C 7 ) -alkylaminocarbonyl- (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -haloalkylaminocarbonyl- (C 1 -C 7 ) -alkyl (C 2 -C 7 ) -alkynyl- (C 1 -C 7 ) -alkylaminocarbonyl- (C 1 -C 4) -alkyl C 7) alkyl, (C3-C7) -Cycloalky - (Ci-C7) - alkylaminocarbonyl (Ci-C7) alkyl, (Ci-C7) -Alkoxycarbonylaminocarbonyl- (Ci-C7) alkyl, aryl (C 1 -C 7) -alkoxycarbonylaminocarbonyl- (C 1 -C 7) -alkyl, (C 1 -C 7) -alkoxycarbonyl- (C 1 -C 7) -alkylaminocarbonyl, hydroxycarbonyl- (C 1 -C 7) -alkylaminocarbonyl, aryl- (C 1 -C 7) -alkoxycarbonyl- (C 1 -C 7) -alkylaminocarbonyl, aminocarbonyl- (C 1 -C 7) -alkylaminocarbonyl, (C 1 -C 7) -alkylaminocarbonyl- (C 1 -C 7) -alkylaminocarbonyl. (C 3 -C 7 ) -cycloalkylaminocarbonyl- (C 1 -C 7 ) -alkylaminocarbonyl, (C 3 -C 7 ) -cycloalkyl- (C 1 -C 7 ) -alkylaminocarbonyl, (C 3 -C 7 ) -cycloalkyl- (C 1 -C 7 ) -alkylaminocarbonyl (C 1 -C 7 ) -alkyl, (C 3 -C 7 ) -cycloalkyl- (C 1 -C 7 ) -alkylaminocarbonyi (C 1 -C 7 ) -alkylaminocarbonyl, (C 2 -C 7 ) -alkenyl- (C 1 -C 7 ) - alkylaminocarbonyl, (C 2 -C 7) -alkenylaminocarbonyl- (C 1 -C 7) -alkyl, (C 2 -C 7) -alkenyl- (C 1 -C 7) -alkylaminocarbonyl- (C 1 -C 7) -alkyl (C 1 -C 7) -alkylcarbonyl, ( C3-C7) -cycloalkylcarbonyl, arylcarbonyl, formyl, hydroxyiminomethyl, aminoiminomethyl, (C 1 -C 7) -alkoxyiminomethyl, (C 1 -C 7) -alkylaminoiminomethyl, bis [(C 1 -C 7) -alkyl] aminoiminomethyl, (C 3 -C 7) -cycloalkoxyiminomethyl , (C 1 -C 7) -cycloalkyl- (C 1 -C 7) -alkoximinomethyl, aryloximinomethyl, aryl- (C 1 -C 7) -alkoxyiminomethyl, aryl- (C 1 -C 7) -alkylaminoiminomethyl, (C 2 -C 7) -alkenyloxyiminomethyl,
Arylaminoiminomethyl, Arylsulfonylaminoiminomethyl,  Arylaminoiminomethyl, arylsulfonylaminoiminomethyl,
Hydroxycarbonylheterocyclyi-(CrC7)-alkyl, (C1-C7)- Alkoxycarbonylheterocyclyl-(CrC7)-alkyl, Hydroxycarbonyl-(C3-C7)- cycloalkyl-(Ci-C7)-alkyl, (Ci-C7)-Alkoxycarbonyl-(C3-C7)-cycloalkyl- (d-C7)-alkyl, Hydroxyaminocarbonyl, (Ci-C7)-Alkoxyaminocarbonyl, Aryl- (Ci-C7)-alkoxyaminocarbonyl, (Ci-C6)-Alkoxycarbonyl-heterocyclyl-N- carbonyl, (Ci-C6)-Alkoxycarbonyl-(Ci-C6)-alkyl- heterocyclylidenaminocarbonyl, (Ci-C6)-Alkoxycarbonylheterocyclyliden- (Ci-C6)-alkylaminocarbonyl, (Ci-Cc>)-Alkoxycarbonyl-(Ci-C6)-Alkyl((Ci- C6)-alkyi)aminocarbonyl, (Ci-CeJ-AlkoxycarbonyKCs-Ce)- cycloalkylidenaminocarbonyl, Heterocyclyl-N-carbonyl, (CrCeJ-Alkoxy- (Ci-C6)-alkylaminocarbonyl steht, Hydroxycarbonylheterocyclyl (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -alkoxycarbonyl-heterocyclyl- (C 1 -C 7 ) -alkyl, hydroxycarbonyl- (C 3 -C 7 ) -cycloalkyl- (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -alkoxycarbonyl- C 3 -C 7 ) -cycloalkyl- (C 1 -C 7 ) -alkyl, hydroxyaminocarbonyl, (C 1 -C 7 ) -alkoxyaminocarbonyl, aryl- (C 1 -C 7 ) -alkoxyaminocarbonyl, (C 1 -C 6 ) -alkoxycarbonyl-heterocyclyl-N-carbonyl (Ci-C6) alkoxycarbonyl (Ci-C6) alkyl heterocyclylidenaminocarbonyl, (Ci-C6) -Alkoxycarbonylheterocyclyliden- (Ci-C6) alkylaminocarbonyl, (C Cc>) alkoxycarbonyl (Ci-C6) - Alkyl ((C 1 -C 6) alkyl) aminocarbonyl, (C 1 -C 6 -alkoxycarbonyKCs-Ce) - cycloalkylideneaminocarbonyl, heterocyclyl-N-carbonyl, (C 1 -C 6 -alkoxy- (C 1 -C 6) -alkylaminocarbonyl,
R7, R8, R9, R10, R11 und R12 unabhängig voneinander für Wasserstoff, (C1-C7)- Alkyl, (C3-C7)-Cycloalkyl, (C2-C7)-Alkenyl, (C2-C7)-Alkenyl-(Ci-C7)-alkyi, (Ci-C7)-Alkoxy-(Ci-C7)-alkyl, Hydroxy-(Ci-C7)-alkyl, (Ci-C7)-Haloalkyl, (C2-C7)-Haloalkenyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-alkyl, (Ci-C7)-Alkoxy- (CrC7)-haloalkyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-haloaikyl, (CrC7)-Alkoxy, (Ci-C7)-Alkylthio, (Ci-C7)-Aikylamino, Halogen, Amino stehen, wobei mindestens eine der Gruppen R7, R8, R9, R1Ü, R1 1 und R12 nicht für Wasserstoff steht und R3 und R4 mit dem Atom, an das sie gebunden sind, eine exo-Alkylidengruppe oder einen vollständig gesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 6-gliedrigen Ring bilden, R 7 , R 8 , R 9 , R 10 , R 11 and R 12 independently of one another represent hydrogen, (C 1 -C 7 ) -alkyl, (C 3 -C 7 ) -cycloalkyl, (C 2 -C 7 ) -alkenyl, (C2-C7) alkenyl (Ci-C 7) -alkyi, (Ci-C7) alkoxy (Ci-C7) alkyl, hydroxy (Ci-C7) alkyl, (Ci-C 7 ) -haloalkyl, (C2-C7) haloalkenyl, (Ci-C7) haloalkoxy (Ci-C7) alkyl, (Ci-C7) alkoxy (CrC 7) -haloalkyl, (Ci-C 7 ) -haloalkoxy- (Ci-C7) -haloaikyl, (CrC 7 ) alkoxy, (Ci-C7) alkylthio, (Ci-C7) -Aikylamino, halogen, amino, wherein at least one of the groups R 7 , R 8, R 9, R 1R, R 1 1 and R 12 is not hydrogen, and R 3 and R 4 with the atom to which they are attached, an exo-alkylidene group or a fully saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 3 to 6 form a -ligmoid ring,
R1 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig R 1 and R 11 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, form a saturated or partially saturated 5 to 7-membered ring, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted,
R1 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig R 1 and R 9 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, form a saturated or partially saturated 3 to 7-membered ring, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted,
R3 und R7 mit den Atomen, an die sie gebunden sind, einen vollständig R 3 and R 7 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, form a saturated or partially saturated 5 to 7-membered ring, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted,
R3 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig R 3 and R 11 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, form a saturated or partially saturated 3 to 7-membered ring, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted,
R1 und R3 mit den Atomen, an die sie gebunden sind, einen vollständig R 1 and R 3 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, form a saturated or partially saturated 5 to 7-membered ring, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted,
R7 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig R 7 and R 11 complete with the atoms to which they are attached
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, R3 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, form a saturated or partially saturated 5 to 7-membered ring, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted, R 3 and R 9 with the atoms to which they are attached, a fully saturated or partially saturated, optionally interrupted by O (oxygen), S (sulfur) or a group NH, NR 37 and optionally further substituted 3 to 7-membered ring form,
R7 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig R 7 and R 9 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, form a saturated or partially saturated 3 to 7-membered ring, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted,
R13, R14, R15 und R16 unabhängig voneinander für Wasserstoff, Halogen, Nitro, Amino, Cyano, (CrC7)-Alkyl, Aryl, Heteroaryl, (C3-C7)-Cycloalkyl, (C4-C7)- Cycloalkenyl, (C2-C7)-Alkenyl, (C2-C7)-Alkinyl, (C2-C7)-Alkenyl-(Ci-C7)- alkyl, (C2-C7)-Alkinyl-(Ci-C7)-alkyl, Hydroxy, (Ci-C7)-Alkoxy, (C1-C7)- Alkoxy-(Ci-C7)-alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkyl, Hydroxy-(d-C7)- alkyl, (d-C7)-Haloalkoxy, (d-C7)-Haloalkyl, (C2-C7)-Haloalkenyl, (C2-C7)- Haloalkinyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-alkyl, (Ci-C7)-Alkoxy-(Ci-C7)- haloalkyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-haloalkyl, Hydrothio, (C1-C7)- Alkylthio, (Ci-C7)-Haloalkylthio, (Ci-C7)-Alkylthio-(Ci-C7)-alkyl, (C1-C7)- Haloalkylthio-(CrC7)-alkyl, (d-C7)-Alkylamino, Bis-[(CrC7)-alkyl]amino, (C2-C7)-Alkenylamino, (C3-C7)-Cycloalkylamino, (C1-C7)- Alkylcarbonylamino, (C3-C7)-Cycloalkylcarbonylamino, R 13, R 14, R 15 and R 16 are independently hydrogen, halogen, nitro, amino, cyano, (CrC 7) alkyl, aryl, heteroaryl, (C 3 -C 7) cycloalkyl, (C 4 -C 7) - cycloalkenyl, (C 2 -C 7) alkenyl, (C 2 -C 7) -alkynyl, (C 2 -C 7) alkenyl (Ci-C7) - alkyl, (C2-C7) alkynyl (Ci-C7) alkyl, hydroxy, (Ci-C7) alkoxy, (C1-C7) - alkoxy (Ci-C7) alkoxy, (Ci-C7) alkoxy ( Ci-C 7) alkyl, hydroxy (dC 7) - alkyl, (dC 7) -haloalkoxy, (dC 7) -haloalkyl, (C2-C7) haloalkenyl, (C2-C7) - haloalkynyl, (C -C 7) haloalkoxy (Ci-C7) alkyl, (Ci-C7) alkoxy (Ci-C7) - haloalkyl, (Ci-C7) haloalkoxy (Ci-C7) - haloalkyl, hydrothio, (C 1 -C 7 ) -alkylthio, (C 1 -C 7 ) -haloalkylthio, (C 1 -C 7 ) -alkylthio (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -haloalkylthio (C 1 -C 7 ) alkyl, (dC 7) -alkylamino, - bis [(-C 7) alkyl] amino, (C 2 -C 7) alkenylamino, (C3-C7) cycloalkylamino, (C1-C7) - alkylcarbonylamino, (C 3 -C 7 ) -cycloalkylcarbonylamino,
Arylcarbonylamino, Heteroarylcarbonylamino, Formylamino, (C1-C7)- Haloalkylcarbonylamino, (Ci-C7)-Alkoxycarbonylamino, (C1-C7)- Alkylaminocarbonylamino, (C1-C7)- Alkyl[(d-C7)- Alkyl]aminocarbonylamino, (Ci-C7)-Alkylsulfonylamino, (C3-C7)- Cycloalkylsulfonylamino, Arylsulfonylamino, Hetarylsulfonylamino, Sulfonyl-(Ci-C7)-haloalkylamino, Amino-(Ci-C7)-alkylsulfonyl, Amino- (CrC7)-haloalkylsulfonyl, (Ci-C7)-Alkylaminosulfonyl, Bis[(Ci-C7)- alkyljaminosulfonyl, (C3-C7)-Cycloalkylaminosulfonyl, (C1-C7)- Haloalkylaminosulfonyl, Heteroarylaminosulfonyi, Arylaminosulfonyl, Aryl- (Ci-C7)-alkylaminosulfonyl, (d-C7)-Alkylsulfonyl, (C3-C7)- Cycloalkylsulfonyl, Arylsulfonyl, Hydroxycarbonyl, (C1-C7)- Alkoxycarbonyl, (C3-C7)-Cycloalkoxycarbonyl, (C3-C7)-Cycloalkyl-(Ci-C7)- alkoxycarbonyl, Aryloxycarbonyl, Aryl-(d-C7)-alkoxycarbonyl, (C2-C7)- Alkenyloxycarbonyl, (C2-C7)-Alkinyloxycarbonyl, Aminocarbonyl, (C1-C7)- Alkylaminocarbonyl, Bis[(Ci-C7)-alkyl]aminocarbonyl, (C1-C7)- Alkyl[(Ci-C7)-Alkyl]aminocarbonyl, (Ci-C7)-Alkyl[(Ci-C7)- Alkoxy]aminocarbonyl, (C2-C7)-Alkenylaminocarbonyl, (C3-C7)- Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(d-C7)- alkylaminocarbonyl stehen, Arylcarbonylamino, heteroarylcarbonylamino, formylamino, (C1-C7) - Haloalkylcarbonylamino, (Ci-C 7) alkoxycarbonylamino, (C1-C7) - alkylaminocarbonylamino, (C1-C7) - alkyl [(dC 7) - alkyl] aminocarbonylamino, (C -C 7 ) -alkylsulfonylamino, (C 3 -C 7 ) -cycloalkylsulfonylamino, arylsulfonylamino, hetarylsulfonylamino, sulfonyl- (C 1 -C 7 ) -haloalkylamino, amino- (C 1 -C 7 ) -alkylsulfonyl, amino- (C 1 -C 7 ) -haloalkylsulfonyl, (Ci-C 7) alkylaminosulfonyl, bis [(Ci-C 7) - alkyljaminosulfonyl, (C3-C 7) -Cycloalkylaminosulfonyl, (C1-C7) - Haloalkylaminosulfonyl, Heteroarylaminosulfonyi, arylaminosulfonyl, aryl- (Ci-C7) - alkylaminosulfonyl, (C 1 -C 4 ) -alkylsulfonyl, (C 3 -C 7 ) -cycloalkylsulfonyl, arylsulfonyl, hydroxycarbonyl, (C 1 -C 7 ) - Alkoxycarbonyl, (C3-C7) -cycloalkoxycarbonyl, (C3-C7) -cycloalkyl- (Ci-C7) -alkoxycarbonyl, aryloxycarbonyl, aryl- (d-C7) -alkoxycarbonyl, (C2-C7) -alkenyloxycarbonyl, (C2-C7 ) -Alkinyloxycarbonyl, aminocarbonyl, (C 1 -C 7 ) -alkylaminocarbonyl, bis [(C 1 -C 7 ) -alkyl] aminocarbonyl, (C 1 -C 7 ) -alkyl [(C 1 -C 7 ) -alkyl] aminocarbonyl, (C 1 -C 7 ) -Alkyl [(C 1 -C 7 ) -alkoxy] -aminocarbonyl, (C 2 -C 7 ) -alkenylaminocarbonyl, (C 3 -C 7 ) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 7 ) -alkylaminocarbonyl,
A1, A2, A3 und A4 gleich oder verschieden sind und unabhängig voneinander für N (Stickstoff) oder die Gruppierungen C-H, C-CH3, C-F, C-Cl, C-Br, C-l, C-OCF3, C-OCH3, C-CF3, C-CO2H, C-CO2CH3 stehen, wobei jedoch in keinem Fall mehr als zwei N -Atome benachbart sind, A 1 , A 2 , A 3 and A 4 are the same or different and are each independently N (nitrogen) or the groupings CH, C-CH 3 , CF, C-Cl, C-Br, Cl, C-OCF 3, C -OCH3, C-CF3, C-CO2H, C-CO2CH3, but in no case more than two N atoms are adjacent,
R17 und R18 unabhängig voneinander für Wasserstoff, Halogen, (d-C7)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (C3-C7)-Cycloalkyl, (C2-C7)-Alkenyl, (C2-C7)-Alkinyl, (CrC7)-Alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkyl, Aryloxy- (Ci-C7)-alkyl, (Ci-C7)-Haloalkoxy, (Ci-C7)-Haloalkyl, (Ci-C7)-Haloalkoxy- (Ci-C7)-alkyl, (Ci-C7)-Alkoxy-(Ci-C7)-haloalkyl, (Ci-C7)-Haloalkoxy- (Ci-C7)-haloalkyl, (Ci-C7)-Alkylthio, (Ci-C7)-Haloalkylthio, (C1-C7)- Alkylthio-(d-C7)-alkyl, Hydroxycarbonyl, (Ci-C7)-Alkoxycarbonyl, (C3-C7)- Cycloalkoxycarbonyl, (C3-C7)-Cycloalkyl-(Ci-C7)-alkoxycarbonyl, R 17 and R 18 independently of one another represent hydrogen, halogen, (C 1 -C 7 ) -alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 7 ) -cycloalkyl, (C 2 -C 7 ) -alkenyl, (C 2 -C 7 ) - Alkynyl, (C 1 -C 7 ) -alkoxy, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -alkyl, aryloxy- (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -haloalkoxy, (C 1 -C 4 ) -alkoxy, C 7) -haloalkyl, (Ci-C7) haloalkoxy (Ci-C7) alkyl, (Ci-C7) alkoxy (Ci-C7) haloalkyl, (Ci-C7) haloalkoxy (C 1 -C 7 ) -haloalkyl, (C 1 -C 7 ) -alkylthio, (C 1 -C 7 ) -haloalkylthio, (C 1 -C 7 ) -alkylthio (C 1 -C 7 ) -alkyl, hydroxycarbonyl, (C 1 -C 7 ) Alkoxycarbonyl, (C 3 -C 7) -cycloalkoxycarbonyl, (C 3 -C 7) -cycloalkyl- (C 1 -C 7) -alkoxycarbonyl,
Aryloxycarbonyl, Aryl-(d-C7)-alkoxycarbonyl, (C2-C7)- Alkenyloxycarbonyl, (C2-C7)-Alkinyloxycarbonyl, Aminocarbonyl, (C1-C7)- Alkylaminocarbonyl, Bis[(Ci-C7)-alkyl]aminocarbonyl, (C1-C7)- Alkyl[(Ci-C7)-Alkyl]aminocarbonyl, (Ci-C7)-Alkyl[(Ci-C7)- Alkoxy]aminocarbonyl, (C2-C7)-Alkenylaminocarbonyl, (C3-C7)- Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C7)- alkylaminocarbonyl stehen, Aryloxycarbonyl, aryl- (C 1 -C 7) -alkoxycarbonyl, (C 2 -C 7) -alkenyloxycarbonyl, (C 2 -C 7) -alkynyloxycarbonyl, aminocarbonyl, (C 1 -C 7) -alkylaminocarbonyl, bis [(C 1 -C 7) -alkyl] aminocarbonyl, (C 1 -C 7 ) -alkyl [(C 1 -C 7 ) -alkyl] aminocarbonyl, (C 1 -C 7 ) -alkyl [(C 1 -C 7 ) -alkoxy] -aminocarbonyl, (C 2 -C 7 ) -alkenylaminocarbonyl, (C 3 -C 4) -alkyl C7) - cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 7) -alkylaminocarbonyl,
A5 für S (Schwefel), O (Sauerstoff) oder die Gruppierungen N-H, N-CH3, N- CH2CH3, N-CH(CH3)2, N-C02t-Bu, N-Aryl, N-Heteroaryl, N-Heterocyclyl steht. R19, R20, R23 und R24 unabhängig voneinander für Wasserstoff, (Ci-C-7)-Alkyl, Halogen, (C3-C-7)-Cycloalkyl, Aryl, Heteroaryl, Heterocyclyl, (C2-C7)- Alkenyi, (C2-C7)-Alkenyl-(Ci-C7)-alkyl, Aryl-(d-C7)-alkyl, (C,-C7)-Alkoxy, (Ci-C7)-Alkoxy-(CrC7)-alkoxy, (Ci-C7)-Alkoxy-(d-C7)-alkyl, Hydroxy, (d-C7)-Haloalkyl, (CrC7)-Haloalkylthio stehen, A 5 represents S (sulfur), O (oxygen) or the groupings NH, N-CH 3 , N-CH 2 CH 3 , N-CH (CH 3 ) 2 , N-CO 2 t-Bu, N-aryl, N-heteroaryl, N-heterocyclyl is. R 19 , R 20 , R 23 and R 24 independently of one another represent hydrogen, (C 1 -C 7) -alkyl, halogen, (C 3 -C 7) -cycloalkyl, aryl, heteroaryl, heterocyclyl, (C 2 -C 7) - Alkenyi, (C2-C7) alkenyl (Ci-C7) alkyl, aryl (dC 7) alkyl, (C, -C 7) alkoxy, (Ci-C7) alkoxy (CrC 7) alkoxy, (Ci-C7) alkoxy (dC 7) alkyl, hydroxy, (dC 7) -haloalkyl, (CrC 7) are haloalkylthio,
R19 und R23 mit den Atomen, an die sie gebunden sind, einen vollständig R 19 and R 23 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden,  form a saturated or partially saturated, optionally further substituted 5 to 7-membered ring,
A6, A7 gleich oder verschieden sind und unabhängig voneinander für O A 6 , A 7 are the same or different and are each independently O.
(Sauerstoff), S (Schwefel), N-H, N-OCH3, N-CH3 oder die Gruppierung CR21 R22 stehen, wobei jedoch in keinem Fall zwei N-, O- oder S-Atome benachbart sind, und wobei R21 und R22 in der Gruppierung CR21 R22 jeweils gleiche oder verschiedene Bedeutungen gemäß der (Oxygen), S (sulfur), NH, N-OCH3, N-CH 3 or the group CR 21 R 22, but in no case two N, O or S atoms are adjacent, and wherein R 21 and R 22 in the group CR 21 R 22 each have the same or different meanings according to the
nachstehenden Definition haben und  have the following definition and
R21 und R22 unabhängig voneinander für Wasserstoff, Halogen, (Ci-C7)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (C3-C7)-Cycloalkyl, (C2-C7)-Alkenyl, (Ci-C7)-Alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkyl, Aryloxy-(Ci-C7)-alkyl, (CrC7)-Haloalkoxy, (Ci-C7)-Haloalkyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-alkyl, (Ci-C7)-Alkoxy-(Ci-C7)-haloalkyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-haloalkyl, (CrC7)-Alkylthio, (Ci-C7)-Haloalkylthio, (Ci-C7)-Alkylthio-(Ci-C7)-alkyl, Hydroxycarbonyl, (d-C7)-Alkoxycarbonyl , (C:rC7)-Cycloalkoxycarbonyl, (C3-C7)-Cycloalkyl-(Ci-C7)-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(CrC7)- alkoxycarbonyl , (C2-C7)-Alkenyloxycarbonyl , (C2-C7)-Al ki nyloxycarbonyl , Aminocarbonyl, (Ci-C7)-Alkylaminocarbonyl, Bis[(Ci-C7)- alkyljaminocarbonyl, (Ci-C7)-Alkyl[(Ci-C7)-Alkyl]aminocarbonyl, (C1-C7)- Alkyl[(Ci-C7)-Alkoxy]aminocarbonyl, (C2-C7)-Alkenylaminocarbonyl, (C3-C7)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(CrC7)- alkylaminocarbonyl, Amino, (Ci-C7)-Alkylamino, (C:3-C7)-Cycloalkylamino, Bis-[(Ci-C7)-Alkyl]amino stehen, R25, R26, R28 und R29 unabhängig voneinander für Wasserstoff, (Ci-C-7)-Alkyl, Halogen, (C3-C-7)-Cycloalkyl, Aryl, Heteroaryl, Heterocyciyi, (C2-C7)- Alkenyl, Aryl-(Ci-C7)-alkyl, (CrC7)-Alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkoxy,R 21 and R 22 are independently hydrogen, halogen, (Ci-C 7) alkyl, aryl, heteroaryl, heterocyclyl, (C3-C7) cycloalkyl, (C2-C7) alkenyl, (Ci-C 7 ) alkoxy, (Ci-C7) alkoxy (Ci-C7) alkyl, aryloxy (Ci-C7) alkyl, (CrC 7) haloalkoxy, (Ci-C7) haloalkyl, ( C 1 -C 7 ) -haloalkoxy- (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -haloalkyl, (C 1 -C 7 ) -haloalkoxy- (C 1 -C 7 ) haloalkyl, (CrC 7) alkylthio, (Ci-C 7) haloalkylthio, (Ci-C7) -alkylthio (Ci-C 7) alkyl, hydroxycarbonyl, (dC 7) alkoxycarbonyl, (C rC 7 ) -Cycloalkoxycarbonyl, (C 3 -C 7 ) -cycloalkyl- (C 1 -C 7 ) -alkoxycarbonyl, aryloxycarbonyl, aryl- (C 1 -C 7 ) -alkoxycarbonyl, (C 2 -C 7 ) -alkenyloxycarbonyl, (C 2 -C 7 ) - Alkenyloxycarbonyl, aminocarbonyl, (C 1 -C 7 ) -alkylaminocarbonyl, bis [(C 1 -C 7 ) -alkylaminocarbonyl, (C 1 -C 7 ) -alkyl [(C 1 -C 7 ) -alkyl] aminocarbonyl, (C 1 -C 7 ) -alkyl ) - alkyl [(C 1 -C 7 ) -alkoxy] -aminocarbonyl, (C 2 -C 7 ) -alkenylaminocarbonyl, (C 3 -C 7 ) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 7 ) -alkylaminocarbony l, amino, (Ci-C 7 ) -alkylamino, (C: 3-C 7 ) -cycloalkylamino, bis - [(Ci-C 7 ) -alkyl] amino, R 25 , R 26 , R 28 and R 29 independently of one another are hydrogen, (C 1 -C 7) -alkyl, halogen, (C 3 -C 7) -cycloalkyl, aryl, heteroaryl, heterocyclic, (C 2 -C 7) - Alkenyl, aryl- (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -alkoxy, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -alkoxy,
(Ci-C7)-Alkoxy-(Ci-C7)-alkyl, (Ci-C7)-Haloalkyl stehen, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -alkyl, (C 1 -C 7 ) -haloalkyl,
A8 für O (Sauerstoff), S (Schwefel), N-H, N-CH3, N-OCH3 oder die Gruppierung CHR27 steht und wobei R27 in der Gruppierung CHR27 die Bedeutung gemäß der nachstehenden Definition hat, A 8 is O (oxygen), S (sulfur), NH, N-CH 3 , N -OCH 3 or the moiety CHR 27 , and wherein R 27 in the moiety CHR 27 has the meaning as defined below,
R27 für Wasserstoff, Halogen, (C1-C7)- Alkyl, Aryl, Heteroaryl, Heterocyciyi, R 27 is hydrogen, halogen, (C 1 -C 7) -alkyl, aryl, heteroaryl, heterocyclic,
(C3-C7)-Cycloalkyl, (C2-C7)-Alkenyl, (CrC7)-Alkoxy, (Ci-C7)-Alkoxy- (CrC7)-alkyl, Aryloxy-(Ci-C7)-alkyl, (Ci-C7)-Haloalkoxy, (Ci-C7)-Haloalkyl, (Ci-C7)-Alkoxy-(Ci-C7)-haloalkyl, (Ci-C7)-Haloalkoxy-(Ci-C7)-haloalkyl, (CrC7)-Alkylthio, (Ci-C7)-Haloalkylthio, (Ci-C7)-Alkylthio-(Ci-C7)-alkyl, Hydroxycarbonyl, (Ci-C7)-Alkoxycarbonyl, (C: C7)-Cycloalkoxycarbonyl, Aryl-(Ci-C7)-alkoxycarbonyl, (C2-C7)-Alkenyloxycarbonyl, (C2-C7)- Alkinyloxycarbonyl, Aminocarbonyl, (Ci-C7)-Alkylaminocarbonyl, (C 3 -C 7 ) -cycloalkyl, (C 2 -C 7 ) -alkenyl, (CrC 7 ) -alkoxy, (Ci-C 7 ) -alkoxy- (CrC 7 ) -alkyl, aryloxy- (Ci-C 7 ) -alkyl, (C 1 -C 7 ) -haloalkoxy, (C 1 -C 7 ) -haloalkyl, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -haloalkyl, (C 1 -C 7 ) -haloalkoxy- (Ci -C 7) haloalkyl, (CrC 7) alkylthio, (Ci-C 7) haloalkylthio, (Ci-C7) -alkylthio (Ci-C 7) alkyl, hydroxycarbonyl, (Ci-C7) alkoxycarbonyl , (C: C7) -cycloalkoxycarbonyl, aryl- (C 1 -C 7) -alkoxycarbonyl, (C 2 -C 7) -alkenyloxycarbonyl, (C 2 -C 7) -alkynyloxycarbonyl, aminocarbonyl, (C 1 -C 7) -alkylaminocarbonyl,
Bis[(Ci-C7)-alkyl]aminocarbonyl, (Ci-C7)-Alkyl[(Ci-C7)- Alkyl]aminocarbonyl, (Ci-C7)-Alkyl[(Ci-C7)-Alkoxy]aminocarbonyl, Bis [(C 1 -C 7 ) -alkyl] aminocarbonyl, (C 1 -C 7 ) -alkyl [(C 1 -C 7 ) -alkyl] aminocarbonyl, (C 1 -C 7 ) -alkyl [(C 1 -C 7 ) -alkoxy] -aminocarbonyl,
(C2-C7)-Alkenylaminocarbonyl, (C3-C7)-Cycloalkylaminocarbonyl,  (C 2 -C 7) -alkenylaminocarbonyl, (C 3 -C 7) -cycloalkylaminocarbonyl,
Arylaminocarbonyl, Aryl-(Ci-C7)-alkylaminocarbonyl, Amino, (C1-C7)- Alkylamino, (C:3-C7)-Cycloalkylamino, Bis-[(CrC7)-Alkyl]amino steht,  Arylaminocarbonyl, aryl- (C 1 -C 7) -alkylaminocarbonyl, amino, (C 1 -C 7) -alkylamino, (C 3 -C 7) -cycloalkylamino, bis- [(C 1 -C 7) -alkyl] -amino,
R30, R31 , R32, R34, R35 und R36 unabhängig voneinander für Wasserstoff, (C1-C7)- Alkyl, Halogen, (C3-C7)-Cycloalkyl, Aryl, Heteroaryl, Heterocyciyi, (C2-C7)- Alkenyl, (CrC7)-Alkoxy, (Ci-C7)-Alkoxy-(Ci-C7)-alkoxy, (Ci-C7)-Alkoxy- (Ci-C7)-alkyl, (Ci-C7)-Haloalkyl, (Ci-C7)-Alkylthio, (Ci-C7)-Haloalkylthio stehen, R 30 , R 31 , R 32 , R 34 , R 35 and R 36 independently represent hydrogen, (C 1 -C 7) -alkyl, halogen, (C 3 -C 7) -cycloalkyl, aryl, heteroaryl, heterocyclic, (C 2 -C 7) Alkenyl, (C 1 -C 7 ) -alkoxy, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -alkoxy, (C 1 -C 7 ) -alkoxy- (C 1 -C 7 ) -alkyl, C 7 ) -haloalkyl, (C 1 -C 7 ) -alkylthio, (C 1 -C 7 ) -haloalkylthio,
A9 für O (Sauerstoff), S (Schwefel), N-H, N-CH3, N-OCH3 oder die Gruppierung CHR33 steht und wobei R33 in der Gruppierung CHR33 die Bedeutung gemäß der nachstehenden Definition hat und R33 für Wasserstoff, Halogen, (Ci-C7)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (C3-C7)-Cycloalkyl, (C2-C7)-Alkenyl, (d-C7)-Alkoxy, (Ci-C7)-Alkoxy- (d-C7)-alkyl, Aryloxy-(Ci-C7)-alkyl, (d-C7)-Haloalkoxy, (Ci-C7)-Haloalkyl, (Ci-C7)-Alkylthio, (CrC7)-Haloalkylthio, Hydroxycarbonyl, (C1-C7)- Alkoxycarbonyl, (C3-C7)-Cycloalkoxycarbonyl, Aryl-(d-C7)- alkoxycarbonyl , (C2-C7)-Alkenyloxycarbonyl , (C2-C7)-Al ki nyloxycarbonyl , Aminocarbonyl, (Ci-C7)-Alkylaminocarbonyl, Bis[(d-C7)- alkyl]aminocarbonyl, (CrC7)-Alkyl[(Ci-C7)-Alkyl]aminocarbonyl, (C1-C7)- Alkyl[(Ci-C7)-Alkoxy]aminocarbonyl, (C2-C7)-Alkenylaminocarbonyl, (C3-C7)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-C7)- alkylaminocarbonyl, Amino, (Ci-C7)-Alkylamino, (C3-C7)-Cycloalkylamino, Bis-[(Ci-C7)-Alkyl]amino steht, A 9 is O (oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the group CHR 33 , and wherein R 33 in the group CHR 33 has the meaning as defined below and R 33 is hydrogen, halogen, (C 1 -C 7 ) -alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 7 ) -cycloalkyl, (C 2 -C 7 ) -alkenyl, (C 1 -C 7 ) -alkoxy, (Ci -C 7) alkoxy (dC 7) alkyl, aryloxy (Ci-C7) alkyl, (dC 7) haloalkoxy, (Ci-C7) haloalkyl, (Ci-C7) alkylthio, (CrC 7) haloalkylthio, hydroxycarbonyl, (C1-C7) - alkoxycarbonyl, (C3-C 7) cycloalkoxycarbonyl, aryl (dC 7) - alkoxycarbonyl, (C2-C7) alkenyloxycarbonyl, (C2-C7) Al ki nyloxycarbonyl, aminocarbonyl, (Ci-C 7) alkylaminocarbonyl, bis [(dC 7) - alkyl] aminocarbonyl, (CrC 7) alkyl [(Ci-C 7) alkyl] aminocarbonyl, (C1-C7) - alkyl [(C 1 -C 7 ) -alkoxy] aminocarbonyl, (C 2 -C 7 ) -alkenylaminocarbonyl, (C 3 -C 7 ) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 7 ) -alkylaminocarbonyl, amino, C 7 ) -alkylamino, (C 3 -C 7 ) -cycloalkylamino, bis - [(C 1 -C 7 ) -alkyl] -amino,
R37 für (Ci-C7)-Alkyl, Aryl, Heteroaryl, Heterocyclyl, (C3-C7)-Cycloalkyl, (C2-C7)- Alkenyl, (d-C7)-Alkoxy, (Ci-C7)-Alkoxy-(CrC7)-alkyl, Aryloxy-(Ci-C7)- alkyl, (Ci-C7)-Alkoxycarbonyl, (C3-C7)- Cycloalkoxycarbonyl, Aryl-(d-C7)- alkoxycarbonyl , (C2-C7)-Alkenyloxycarbonyl , (C2-C7)-Al ki nyloxycarbonyl , (Ci-C7)-Alkylcarbonyl, (C3-C7)-Cycloalkylcarbonyl, Arylcarbonyl, R 37 is (Ci-C7) alkyl, aryl, heteroaryl, heterocyclyl, (C 3 -C 7) cycloalkyl, (C2-C7) - alkenyl, (dC 7) alkoxy, (Ci-C7) - alkoxy (-C 7) alkyl, aryloxy (Ci-C7) - alkyl, (Ci-C 7) alkoxycarbonyl, (C3-C7) - cycloalkoxycarbonyl, aryl (dC 7) - alkoxycarbonyl, (C2- C 7) alkenyloxycarbonyl, (C2-C7) -Al ki nyloxycarbonyl, (Ci-C 7) alkylcarbonyl, (C3-C7) cycloalkylcarbonyl, arylcarbonyl,
Heteroarylcarbonyl steht.  Heteroarylcarbonyl stands.
13. Substituierte l -(Arylethinyl)-, 1 -(Heteroarylethinyi)-, l-(Heterocyclylethinyl)- und 1 -(Cyloalkenylethinyl)-bicycloalkanole der allgemeinen Formel (I) gemäß 13. Substituted 1 - (arylethynyl) -, 1 - (heteroarylethinyi) -, 1- (heterocyclylethynyl) - and 1 - (cycloalkenylethynyl) bicycloalkanols of the general formula (I) according to
Anspruch 12 oder deren Salze, worin  Claim 12 or its salts, wherein
[X-Y] für die Gruppierung [X-Y] for grouping
[Χ-ΥΓ steht, [Χ-ΥΓ stands,
Q für die Gruppierungen Q-1 bis Q-6 Q for the groupings Q-1 to Q-6
steht, wobei R13, R14, R15, R16, R17, R18, R19, R20, R23, R24, R25. R26, R28, R29, R30, R3 , R32, R34, R35 und R36 sowie A1 bis A9 jeweils die Bedeutung gemäß der nachstehenden Definitionen haben und wobei der Pfeil für eine Bindung zur jeweiligen Gruppierung C-R6 in der allgemeinen Formel (I) steht, wherein R 13 , R 14 , R 15 , R 16 , R 17 , R 18 , R 19 , R 20 , R 23 , R 24 , R 25 . R 26 , R 28 , R 29 , R 30 , R 3 , R 32 , R 34 , R 35 and R 36 and A 1 to A 9 each have the meaning of the definitions below and wherein the arrow indicates a bond to the respective moiety CR 6 in the general formula (I),
R1 für (Ci-C6)-Alkyl, (C3-C6)-Cycloalkyl, (C4-C6)-Cycloalkenyl, (C2-C6)- Alkenyl, (C2-C6)-Alkinyl, (C2-C6)-Alkenyl-(Ci-C6)-alkyl, (C2-C6)-Alkinyl- (Ci-C6)-alkyl, (Ci-C6)-Alkoxy-(Ci-C6)-alkyl, Hydroxy-(Ci-C6)-alkyl, (Ci-Ce)- Haloalkyl, (C2-C6)-Haloalkenyl, (C2-C6)-Haloalkinyl steht, R 1 is (Ci-C 6) -alkyl, (C3-C6) -cycloalkyl, (C 4 -C 6) -cycloalkenyl, (C 2 -C 6) - alkenyl, (C 2 -C 6) alkynyl , (C 2 -C 6) alkenyl (Ci-C 6) alkyl, (C 2 -C 6) alkynyl (Ci-C 6) alkyl, (Ci-C 6) alkoxy (C -C 6) alkyl, hydroxy (Ci-C 6) alkyl, (Ci-Ce) - haloalkyl, (C 2 -C 6) haloalkenyl, (C 2 -C 6) haloalkynyl group,
R2, R3 und R4 unabhängig voneinander für Wasserstoff, Fluor, (Ci-C-6)-Alkyl,R 2 , R 3 and R 4 independently of one another represent hydrogen, fluorine, (C 1 -C 6) -alkyl,
(C3-C6)-Cycloalkyl, (C4-Cr>)-Cycloalkenyl, (C2-C6)-Alkenyl, (C2-C6)-Alkinyl, (C2-C6)-Alkenyl-(Ci-C6)-alkyl, (C2-C6)-Alkinyl-(Ci-C6)-alkyl, (Ci-C6)- Alkoxy-(CrC6)-alkyl, Hydroxy-(CrC6)-alkyl, (CrC6)-Haloalkyl stehen, (C 3 -C 6) cycloalkyl, (C 4 -Cr>) -cycloalkenyl, (C 2 -C 6) alkenyl, (C 2 -C 6) -alkynyl, (C 2 -C 6) alkenyl ( Ci-C 6) alkyl, (C 2 -C 6) alkynyl (Ci-C 6) alkyl, (Ci-C6) - alkoxy (CrC 6) alkyl, hydroxy (CrC 6) - alkyl, (C 1 -C 6 ) -haloalkyl,
R5 für Hydroxy, (CrC6)-Alkoxy, Aryloxy, (C3-C6)-Cycloalkyloxy, (C2-C6)- Alkenyloxy. (C2-C6)-Alkenyl-(Ci-C6)-alkyloxy, (Ci-C6)-Alkoxy-(Ci-C6)- alkyloxy, (Ci-Cr>)-Alkylcarbonyloxy, Arylcarbonyloxy, R 5 is hydroxy, (C 1 -C 6 ) alkoxy, aryloxy, (C 3 -C 6 ) cycloalkyloxy, (C 2 -C 6 ) alkenyloxy. (C 2 -C 6) alkenyl (Ci-C 6) alkyloxy, (Ci-C6) alkoxy (Ci-C 6) - alkyloxy, (Ci-Cr>) alkylcarbonyloxy, arylcarbonyloxy,
Heteroarylcarbonyloxy, (C3-C-6)-Cycloalkylcarbonyloxy, (d-Ce)- Alkoxycarbonyloxy, (C2-C6)-Alkenyloxycarbonyloxy, Aryloxy-(Ci-Ce)- alkyloxy, Aryl-(Ci-Cr>)-alkyloxy, (Ci-C6)-Alkoxy-(Ci-Cr>)-alkoxy-(Ci-C6)- alkyloxy, (Ci-C6)-Alkylthio-(Ci-C6)-alkyloxy, Tris[(Ci-C6)-alkyl]silyloxy, (Ci-C6)-Alkyl-Bis[(Ci-C6)-alkyl]silyloxy, (Ci-C6)-Alkyl-bis(Aryl)silyloxy, Aryl-bis[(Ci-C6)-alkyl]silyloxy, Cycloalkyl-bis[(Ci-C6)-alkyl]silyloxy, Halo- bis[(Ci-C6)-alkyl]silyloxy, Tris[(Ci-C6)-alkyl]silyi-(Ci-C6)-alkoxy-(Ci-C6)- alkyloxy, steht, für (Ci-Ce)- Alkylsulfonylaminocarbonyl, (Ca-Ce)-Heteroarylcarbonyloxy, (C 3 -C 6) -cycloalkylcarbonyloxy, (d-Ce) -alkoxycarbonyloxy, (C 2 -C 6) -alkenyloxycarbonyloxy, aryloxy- (C 1 -C 6) -alkyloxy, aryl- (C 1 -C 4 -cyclo) -alkyloxy, (C 1 -C 6 ) -alkoxy- (C 1 -C 4 -cyclo) -alkoxy- (C 1 -C 6 ) -alkyloxy, (C 1 -C 6 ) -alkylthio (C 1 -C 6 ) -alkyloxy, tris [(C 1 -C 6 ) alkyl] silyloxy, (C 1 -C 6 ) -alkyl-bis [(C 1 -C 6 ) -alkyl] silyloxy, (C 1 -C 6 ) -alkyl-bis (aryl) silyloxy, aryl-bis [(C 1 -C 6 ) -alkyl] silyloxy , Cycloalkyl-bis [(C 1 -C 6 ) -alkyl] silyloxy, halo-bis [(C 1 -C 6 ) -alkyl] silyloxy, tris [(C 1 -C 6 ) -alkyl] silyi- (C 1 -C 6 ) -alkoxy - (Ci-C 6 ) - alkyloxy, stands for (Ci-Ce) - Alkylsulfonylaminocarbonyl, (Ca-Ce) -
Cycloalkylsulfonylaminocarbonyl, Hydroxycarbonyl, (d-Ce)- Alkoxycarbonyl, (C3-Cr,)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci-Cr,)- alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C6)-alkoxycarbonyl, (C2-C-6)- Alkenyloxycarbonyl, (C2-Cr>)-Alkinyloxycarbonyl, (Ci-Cr>)- Haloalkyloxycarbonyl, (Ci-C6)-Alkoxy-(CrC6)-alkoxycarbonyl, (C2-C-6)- Alkenyloxy-(Ci-C6)-alkoxycarbonyl, (Ci-C6)-Alkylamino-(Ci-C6)- alkoxycarbonyl, Tris[(CrC6)-alkyl]silyloxy-(Ci-C6)-alkoxycarbonyl, Bis[(Ci-C6)-Alkyl]amino-(Ci-C6)-alkoxycarbonyl, (Ci-C6)-Alkyl[(Ci-C6)- alkyl]amino-(Ci-C6)-alkoxycarbonyl, Cyano-(CrC6)-alkoxycarbonyl, Heterocyclyl-N-(Ci-C6)-alkoxycarbonyl, Heteroaryloxycarbonyl, Cycloalkylsulfonylaminocarbonyl, hydroxycarbonyl, (d-Ce) -alkoxycarbonyl, (C3-Cr,) -cycloalkoxycarbonyl, (C3-C6) -cycloalkyl- (Ci-Cr,) -alkoxycarbonyl, aryloxycarbonyl, aryl- (Ci-C6) -alkoxycarbonyl, (C2-C6) - alkenyloxycarbonyl, (C2-Cr>) -alkynyloxycarbonyl, (C Cr>) - Haloalkyloxycarbonyl, (Ci-C6) alkoxy (CRC6) -alkoxycarbonyl, (C2-C6) - Alkenyloxy- (C 1 -C 6) alkoxycarbonyl, (C 1 -C 6) alkylamino- (C 1 -C 6) alkoxycarbonyl, tris [(C 1 -C 6) alkyl] silyloxy- (C 1 -C 6) alkoxycarbonyl, bis [(Ci-C 6 ) -alkyl] amino- (C 1 -C 6 ) -alkoxycarbonyl, (C 1 -C 6 ) -alkyl [(C 1 -C 6 ) -alkyl] amino- (C 1 -C 6 ) -alkoxycarbonyl, cyano- (C 1 -C 6) -alkoxycarbonyl , Heterocyclyl-N- (C 1 -C 6) -alkoxycarbonyl, heteroaryloxycarbonyl,
Heteroaryl-(CrC6)-alkoxycarbonyl, Heterocyciyl-(CrC6)-alkoxycarbonyl, Heterocyclyloxycarbonyl, (C2-Cö)-Alkenyl-(Ci-C6)-alkoxycarbonyl, (C2-C6)-Alkinyl-(Ci-C6)-alkoxycarbonyl, Aryl-(C2-C6)-alkinyloxycarbonyl, Aryl-(C2-C6)-alkenyloxycarbonyl, Aminocarbonyl, (Ci-Ce)- Alkylaminocarbonyl, Bis[(CrC6)-alkyl]aminocarbonyl, (Ci-Ce)- Alkyl[(Ci-C6)-Alkyl]aminocarbonyl, (Ci-C6)-Alkyl[(Ci-C6)- Alkoxyjaminocarbonyl, (C2-C6)-Alkenyiaminocarbonyl, (Ca-Ce)- Cycloalkylaminocarbonyl, ArylaminocarbonyL Aryl-(Ci-C6)- alkylaminocarbonyl, Heteroaryl-(Ci-C6)-alkylaminocarbonyl, Cyano- (CrCc -alkylaminocarbonyl, (Ci-C6)-Haloalkylaminocarbonyl, (C2-C6)- Alkinyl-(Ci-C6)-alkylaminocarbonyl, (Ci-Ce)- Alkoxycarbonylaminocarbonyl, Aryl-(Ci-Ce)- alkoxycarbonylaminocarbonyl, Hydroxycarbonyl-(Ci-C6)-alkyl, (Ci-Ce)- Alkoxycarbonyl-(d-C6)-alkyl, (C3-C6)-Cycloalkoxycarbonyl-(CrC6)-alkyl, (C3-C6)-Cyc!oalkyl-(Ci-C6)-alkoxycarbonyl-(Ci-C6)-alkyl. (C2-C6)- Alkenyloxycarbonyl-(Ci-C6)-alkyl, Aryl-(Ci-C6)-alkoxycarbonyl-(CrC6)- alkyl, (Ci-C6)-Alkylaminocarbonyl-(Ci-C6)-alkyl, Aminocarbonyl-(Ci-C6)- a!kyl, Bis[(Ci-C6)-alkyl]aminocarbonyl-(Ci-C6)-alkyl, (C3-C6)- Cycloalkylaminocarbonyl-(Ci-C6)-alkyl, Aryl-(Ci-C6)-alkylaminocarbonyl- (d-C6)-alkyl, Heteroaryl-(Ci-C6)-alkylaminocarbonyl-(Ci-C6)-alkyl, Cyano-(Ci-C6)-alkylaminocarbonyl-(Ci-C6)-alkyl, (d-Ce)- Haloalkylaminocarbonyl-(Ci-C6)-alkyl, (C2-C6)-Alkinyl-(Ci-C6)- alkylaminocarbonyl-(Ci-C6)-alkyl, (C3-C6)-Cycloalkyl-(Ci-C6)- alkylaminocarbonyl-(Ci-Ce)-alkyl, (Ci-C6)-Alkoxycarbonylaminocarbonyl- (d-Cr-alkyl, Aryl-(Ci-C6)-alkoxycarbonylaminocarbonyl-(Ci-C6)-alkyl, (CrC6)-Alkoxycarbonyl-(Ci-C6)-alkylaminocarbonyL Hydroxycarbonyl- (Ci-Cö)-alkylaminocarbonyl, Aryl-(Ci-C6)-alkoxycarbonyl-(Ci-Cö)- alkylaminocarbonyl, Aminocarbonyl-(Ci-C6)-alkylaminocarbonyl, (CI-CG)- Alkylaminocarbonyl-(Ci-C6)-alkylaminocarbonyi. Heteroaryl- (C 1 -C 6) -alkoxycarbonyl, heterocyciyl- (C 1 -C 6) -alkoxycarbonyl, heterocyclyloxycarbonyl, (C 2 -C 6) -alkenyl- (C 1 -C 6) -alkoxycarbonyl, (C 2 -C 6) -alkynyl- (C 1 -C 6) -alkoxycarbonyl, Aryl- (C 2 -C 6) -alkynyloxycarbonyl, aryl- (C 2 -C 6) -alkenyloxycarbonyl, aminocarbonyl, (C 1 -C 6) -alkylaminocarbonyl, bis [(C 1 -C 6) -alkyl] -aminocarbonyl, (C 1 -C 6) -alkyl [(Ci -C 6 ) -alkyl] aminocarbonyl, (C 1 -C 6 ) -alkyl [(C 1 -C 6 ) -alkoxy] aminocarbonyl, (C 2 -C 6 ) -alkenylaminocarbonyl, (C 2 -C 6 ) -cycloalkylaminocarbonyl, arylaminocarbonyL aryl- (C 1 -C 6 ) - alkylaminocarbonyl, heteroaryl- (C 1 -C 6) -alkylaminocarbonyl, cyano- (C 1 -C 6 -alkylaminocarbonyl, (C 1 -C 6) -haloalkylaminocarbonyl, (C 2 -C 6) -alkynyl- (C 1 -C 6) -alkylaminocarbonyl, (C 1 -C 4) Alkoxycarbonylaminocarbonyl, aryl- (Ci-Ce) alkoxycarbonylaminocarbonyl, hydroxycarbonyl- (Ci-C6) -alkyl, (Ci-Ce) -alkoxycarbonyl- (d-C6) -alkyl, (C3-C6) -cycloalkoxycarbonyl- (CrC6) ! alkyl, (C3-C6) -Cyc oalkyl- (Ci-C6) alkoxycarbonyl (Ci-C 6) alkyl (C 2 -C 6) -. alkenyloxycarbonyl (Ci-C6) alkyl, aryl (Ci-C6) -alkoxycarb onyl- (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -alkylaminocarbonyl- (C 1 -C 6 ) -alkyl, aminocarbonyl- (C 1 -C 6 ) -alkyl, bis [(C 1 -C 6 ) -alkyl] -aminocarbonyl- Ci-C 6) alkyl, (C 3 -C 6) - Cycloalkylaminocarbonyl- (C 1 -C 6) -alkyl, aryl- (C 1 -C 6) -alkylaminocarbonyl- (C 1 -C 6) -alkyl, heteroaryl- (C 1 -C 6) -alkylaminocarbonyl- (C 1 -C 6) -alkyl, cyano- (Ci -C 6 ) -alkylaminocarbonyl- (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -haloalkylaminocarbonyl- (C 1 -C 6 ) -alkyl, (C 2 -C 6 ) -alkynyl- (C 1 -C 6 ) -alkylaminocarbonyl- C 1 -C 6 ) -alkyl, (C 3 -C 6 ) -cycloalkyl- (C 1 -C 6 ) -alkylaminocarbonyl- (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -alkoxycarbonylaminocarbonyl- (C 1 -C 6 -alkyl, aryl - (C 1 -C 6) alkoxycarbonylaminocarbonyl- (C 1 -C 6) -alkyl, (C 1 -C 6) -alkoxycarbonyl- (C 1 -C 6) -alkylaminocarbonyL hydroxycarbonyl- (C 1 -C 6) -alkylaminocarbonyl, aryl- (C 1 -C 6) -alkoxycarbonyl- (Ci-Cö) - Alkylaminocarbonyl, aminocarbonyl (Ci-C6) -alkylaminocarbonyl, (CI-CG) - Alkylaminocarbonyl- (Ci-C6) -alkylaminocarbonyi.
(C3-C6)-Cycloalkylaminocarbonyl-(Ci-C6)-alkylaminocarbonyl, (Ca-Ce)- Cycloalkyl-(Ci-C6)-alkylaminocarbonyl, (C3-C6)-Cycloalkyl-(Ci-C6)- alkylaminocarbonyl-(Ci-C6)-alkyl, (C3-C6)-Cycloalkyl-(Ci-C6)- alkylaminocarbonyl-(Ci-C6)-alkylaminocarbonyl, (C2-C6)-Alkenyl-(Ci-C6)- alkylaminocarbonyl, (C2-C6)-Alkenylaminocarbonyl-(Ci-C6)-alkyl, (C2-C6)- Alkenyl-(Ci-C6)-alkylaminocarbonyl-(CrC6)-alkyl, (Ci-Cc)-Alkylcarbonyl, (Cs-CeJ-Cycloalkylcarbonyl, Arylcarbonyl, Formyl, Hydroxyiminomethyl, Aminoiminomethyl, (Ci-C6)-Alkoxyiminomethyl, (Ci-Ce)- Alkylaminoiminomethyl, Bis[(Ci-C6)-alkyl]aminoiminomethyl, (Cs-Ce)- Cycloalkoxyiminomethyl, (C3-C6)-Cycloalkyl-(CrC6)-alkoximinomethyl, Aryloximinomethyl, Aryl-(Ci-C6)-alkoxyiminomethyl, Aryl-(Ci-Ce)- alkylaminoiminomethyl, (C2-C6)-Alkenyloxyiminomethyl, (C 3 -C 6) -cycloalkylaminocarbonyl- (C 1 -C 6) -alkylaminocarbonyl, (Ca-Ce) -cycloalkyl- (C 1 -C 6) -alkylaminocarbonyl, (C 3 -C 6) -cycloalkyl- (C 1 -C 6) -alkylaminocarbonyl- (Ci -C 6) alkyl, (C3-C6) cycloalkyl (Ci-C6) - alkylaminocarbonyl (Ci-C6) alkylaminocarbonyl, (C2-C6) alkenyl (Ci-C6) - alkylaminocarbonyl, ( C 2 -C 6) -alkenylaminocarbonyl- (C 1 -C 6) -alkyl, (C 2 -C 6) -alkenyl- (C 1 -C 6) -alkylaminocarbonyl- (C 1 -C 6) -alkyl, (C 1 -C 6) -alkylcarbonyl, (C 2 -C 6) -cyclo Cycloalkylcarbonyl, arylcarbonyl, formyl, hydroxyiminomethyl, aminoiminomethyl, (Ci-C6) -alkoxyiminomethyl, (Ci-Ce) - alkylaminoiminomethyl, bis [(Ci-C6) -alkyl] aminoiminomethyl, (Cs-Ce) - cycloalkoxyiminomethyl, (C3-C6 ) -Cycloalkyl- (C 1 -C 6) -alkoximinomethyl, aryloximinomethyl, aryl- (C 1 -C 6) -alkoxyiminomethyl, aryl- (C 1 -C 6) -alkylaminoiminomethyl, (C 2 -C 6) -alkenyloxyiminomethyl,
Arylaminoiminomethyl, Arylsulfonylaminoiminomethyl, Arylaminoiminomethyl, arylsulfonylaminoiminomethyl,
Hydroxycarbonylheterocyclyl-(Ci-Cc>)-alkyl, (d-Ce)- Alkoxycarbonylheterocyclyl-(Ci-Cö)-alkyl, Hydroxycarbonyl-(C3-C6)- cycloalkyl-(Ci-C6)-alkyl, (Ci-C6)-Alkoxycarbonyl-(C3-C6)-cycloalkyl- (Ci-Ce)-alkyl, Hydroxyaminocarbonyl, (Ci-C6)-Alkoxyaminocarbonyl, Aryl- (Ci-C6)-alkoxyaminocarbonyl, (Ci-C6)-Alkoxycarbonyl-heterocyclyl-N- carbonyl, (CrC6)-Alkoxycarbonyl-(Ci-C6)-alkyl- heterocyclylidenaminocarbonyl, (CrC6)-Alkoxycarbonylheterocyclyliden- (CrC6)-alkylaminocarbonyl, (Ci-Cö)-Alkoxycarbonyl-(Ci-C6)-Alkyl((Ci- C6)-alkyl)aminocarbonyl, (Ci-C6)-Alkoxycarbonyl-(C3-C6)- cycloalkylidenaminocarbonyl, Heterocyclyl-N-carbonyl, (Ci-Ce)-Alkoxy- (Ci-C6)-alkylaminocarbonyl steht, Hydroxycarbonylheterocyclyl- (Ci-Cc>) alkyl, (d-Ce) - Alkoxycarbonylheterocyclyl- (Ci-COE) alkyl, hydroxycarbonyl (C3-C6) - cycloalkyl- (Ci-C6) alkyl, (Ci-C6) Alkoxycarbonyl- (C 3 -C 6) -cycloalkyl- (C 1 -C 6) -alkyl, hydroxyaminocarbonyl, (C 1 -C 6) -alkoxyaminocarbonyl, aryl- (C 1 -C 6) -alkoxyaminocarbonyl, (C 1 -C 6) -alkoxycarbonyl-heterocyclyl-N - carbonyl, (C 1 -C 6) -alkoxycarbonyl- (C 1 -C 6) -alkyl-heterocyclylideneaminocarbonyl, (C 1 -C 6) -alkoxycarbonylheterocyclylidene (C 1 -C 6) -alkylaminocarbonyl, (C 1 -C 6) -alkoxycarbonyl- (C 1 -C 6) -alkyl ((C 1 -C 4) -cyclo) C6) -alkyl) aminocarbonyl, (C 1 -C 6) -alkoxycarbonyl- (C 3 -C 6) - cycloalkylidenaminocarbonyl, heterocyclyl-N-carbonyl, (C 1 -C 6) -alkoxy- (C 1 -C 6) -alkylaminocarbonyl,
R7, R8, R9, R10, R11 und R12 unabhängig voneinander für Wasserstoff, (CrC6)- Alkyl, (C3-C6)-Cycloalkyi, (C2-C6)-Alkenyl, (C2-C6)-Alkenyl-(Ci-C6)-alkyl, (Ci-C6)-Alkoxy-(Ci-C6)-alkyl, Hydroxy-(CrC6)-alkyl, (Ci-C6)-Haloalkyl, (C2-C6)-Haloalkenyl, (Ci-C6)-Haloalkoxy-(Ci-C6)-alkyl, (Ci-Ce)-Alkoxy- (Ci-C6)-haloalkyl, (Ci-C6)-Haioalkoxy-(Ci-C6)-haloalkyl, (CrC6)-Alkoxy, (Ci-C6)-Alkylthio, (Ci-C6)-Alkylamino, Halogen, Amino stehen, wobei mindestens eine der Gruppen R7, R8, R9, R10, R11 und R12 nicht für Wasserstoff steht und R 7, R 8, R 9, R 10, R 11 and R 12 independently represent hydrogen, (CrC 6) - alkyl, (C 3 -C 6) -Cycloalkyi, (C 2 -C 6) alkenyl, ( C2-C6) alkenyl (Ci-C6) alkyl, (Ci-C6) alkoxy (Ci-C 6) alkyl, hydroxy (CrC 6) alkyl, (Ci-C 6) - haloalkyl, (C 2 -C 6) haloalkenyl, (Ci-C 6) haloalkoxy (Ci-C 6) alkyl, (Ci-Ce) alkoxy (Ci-C 6) -haloalkyl, (Ci- C 6 ) -haloalkoxy- (C 1 -C 6 ) -haloalkyl, (C 1 -C 6 ) -alkoxy, (C 1 -C 6 ) -alkylthio, (C 1 -C 6 ) -alkylamino, halogen, amino, where at least one of the groups R 7 , R 8 , R 9 , R 10 , R 11 and R 12 are not hydrogen and
R3 und R4 mit dem Atom, an das sie gebunden sind, eine exo-Alkylidengruppe oder einen vollständig gesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 6-gliedrigen Ring bilden, R 3 and R 4 with the atom to which they are attached, an exo-alkylidene group or a fully saturated, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted 3 to 6 form a -ligmoid ring,
R1 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig R 1 and R 11 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, form a saturated or partially saturated 5 to 7-membered ring, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted,
R1 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig R 1 and R 9 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, form a saturated or partially saturated 3 to 7-membered ring, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted,
R3 und R7 mit den Atomen, an die sie gebunden sind, einen vollständig R 3 and R 7 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, form a saturated or partially saturated 5 to 7-membered ring, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted,
R3 und R11 mit den Atomen, an die sie gebunden sind, einen vollständig R 3 and R 11 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, saturated or partially saturated, optionally by O (oxygen), S (Sulfur) or a group NH, NR 37 form interrupted and optionally further substituted 3 to 7-membered ring,
R1 und R3 mit den Atomen, an die sie gebunden sind, einen vollständig R 1 and R 3 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, form a saturated or partially saturated 5 to 7-membered ring, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted,
R7 und R 1 mit den Atomen, an die sie gebunden sind, einen vollständig R 7 and R 1 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, form a saturated or partially saturated 5 to 7-membered ring, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted,
R3 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig R 3 and R 9 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, form a saturated or partially saturated 3 to 7-membered ring, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted,
R7 und R9 mit den Atomen, an die sie gebunden sind, einen vollständig R 7 and R 9 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls durch O (Sauerstoff), S (Schwefel) oder eine Gruppierung N-H, N-R37 unterbrochenen und gegebenenfalls weiter substituierten 3 bis 7-gliedrigen Ring bilden, form a saturated or partially saturated 3 to 7-membered ring, optionally interrupted by O (oxygen), S (sulfur) or a grouping NH, NR 37 and optionally further substituted,
R13, R14, R15 und R16 unabhängig voneinander für Wasserstoff, Fluor, Chlor, Brom, lod, Nitro, Amino, Cyano, (Ci-Ce)-Alkyl, gegebenenfalls R 13 , R 14 , R 15 and R 16 independently of one another represent hydrogen, fluorine, chlorine, bromine, iodine, nitro, amino, cyano, (C 1 -C 6) -alkyl, if appropriate
substituiertes Phenyl, Heteroaryl, (Ca-CeJ-Cycloalkyl, (04-ΟΘ)- Cycloalkenyl, (C2-C6)-Alkenyl, (C2-C6)-Alkinyl, (C2-C6)-Alkenyl-(Ci-C6)- alkyl, (C2-C6)-Alkinyl-(Ci-C6)-alkyl, Hydroxy, (Ci-C6)-Alkoxy, (Ci-Ce)- Alkoxy-(Ci-C6)-alkoxy, (Ci-C6)-Alkoxy-(Ci-C6)-alkyl, Hydroxy-(Ci-Ce)- alkyl, (CrCö)-Haloalkoxy, (Ci-C6)-Haloalkyl, (C2-C6)-Haloalkenyl, (C2-C6)- Haloalkinyl, (Ci-C6)-Haloalkoxy-(Ci-C6)-alkyl, (Ci-C6)-Alkoxy-(Ci-C6)- haloalkyl, (Ci-C6)-Haloalkoxy-(Ci-C6)-haloalkyl, Hydrothio, (d-Ce)- Alkylthio, (Ci-C6)-Haloalkylthio, (Ci-C6)-Alkylthio-(Ci-C6)-alkyl, (d-C6)- Haloalkylthio-(CrC6)-alkyl, (Ci-C6)-Alkylamino, Bis-[(Ci-C6)-alkyl]amino, (C2-C6)-Alkenylamino, (Ca-Cr -Cycloalkylamino, (Ci-Ce)- Alkylcarbonylamino, (C3-C6)-Cycloalkylcarbonylamino, substituted phenyl, heteroaryl, (Ca-CeJ-cycloalkyl, (0 4 -ΟΘ) -cycloalkenyl, (C 2 -C 6 ) -alkenyl, (C 2 -C 6 ) -alkynyl, (C 2 -C 6 ) -alkenyl - (Ci-C6) - alkyl, (C 2 -C 6) alkynyl (Ci-C 6) alkyl, hydroxy, (Ci-C6) alkoxy, (Ci-Ce) - alkoxy- (Ci-C 6 ) -alkoxy, (C 1 -C 6 ) -alkoxy- (C 1 -C 6 ) -alkyl, hydroxy- (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -haloalkoxy, (C 1 -C 6 ) -haloalkyl, (C 2 -) C 6) haloalkenyl, (C 2 -C 6) - haloalkynyl, (Ci-C 6) haloalkoxy (Ci-C 6) alkyl, (Ci-C6) alkoxy (Ci-C 6) - haloalkyl, (C 1 -C 6 ) -haloalkoxy- (C 1 -C 6 ) -haloalkyl, hydrothio, (C 1 -C 6 ) -alkylthio, (C 1 -C 6 ) -haloalkylthio, (C 1 -C 6 ) -alkylthio (ci) C 6 ) -alkyl, (dC 6 ) - haloalkylthio (C 1 -C 6 ) -alkyl, (C 1 -C 6 ) -alkylamino, bis - [(C 1 -C 6 ) -alkyl] -amino, (C 2 -C 6) -alkenylamino, (C 1 -C 6 -cycloalkylamino, (C 1 -C 6) -alkylcarbonylamino, (C 3 -C 6) -cycloalkylcarbonylamino,
Arylcarbonylamino, Heteroarylcarbonylamino, Formylamino, (Ci-Ce)- Haloalkylcarbonylamino, (Ci-Cö)-Alkoxycarbonylamino, (d-Ce)- Alkylaminocarbonylamino, (d-Ce)- Alkyl[(Ci-Cr,)- Alkyl]aminocarbonylamino, (Ci-C6)-Alkylsulfonylamino, (Ca-Cr,)- Cycloalkylsulfonylamino, Arylsulfonylamino, Hetarylsulfonylamino, Sulfonyl-(CrC6)-haloalkylamino, Amino-(Ci-Ce)-alkylsulfonyl, Amino- (Ci-C6)-haloalkylsulfonyl, (Ci-C6)-Alkylaminosulfonyl, Bis[(Ci-C6)- alkyljaminosulfonyl, (Ca-CeJ-Cycloalkylaminosulfonyl, (Ci-Ce)- Haloalkylaminosulfonyl, Heteroarylaminosulfonyl, Arylaminosulfonyl, Aryl- (Ci-C6)-alkylaminosulfonyl, (Ci-C6)-Alkylsulfonyl, (C3-C6)- Cycloalkylsulfonyl, Arylsulfonyl, Hydroxycarbonyl, (Ci-Ce)- Alkoxycarbonyl, (Ca-CeJ-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci-Cr,)- alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C6)-alkoxycarbonyl, (C2-Ce)- Alkenyloxycarbonyl, (C2-C6)-Alkinyloxycarbonyl, Aminocarbonyl, (d-Ce)- Alkylaminocarbonyl, Bis[(Ci-C6)-alkyl]aminocarbonyl, (d-Ce)- Alkyl[(Ci-Cö)-Alkyl]aminocarbonyl, (Ci-C6)-Alkyl[(Ci-C6)- Alkoxyjaminocarbonyl, (C2-C6)-Alkenyiaminocarbonyl, (Ca-Ce)- CycloalkylaminocarbonyL Arylaminocarbonyl, Aryl-(Ci-C6)- alkylaminocarbonyl stehen, Arylcarbonylamino, heteroarylcarbonylamino, formylamino, (Ci-Ce) - haloalkylcarbonylamino, (Ci-Cö) alkoxycarbonylamino, (d-Ce) - alkylaminocarbonylamino, (d-Ce) - alkyl [(Ci-Cr,) - alkyl] aminocarbonylamino, ( C 1 -C 6) -alkylsulfonylamino, (Ca-Cr,) -cycloalkylsulfonylamino, arylsulfonylamino, hetarylsulfonylamino, sulfonyl- (C 1 -C 6) -haloalkylamino, amino- (C 1 -C 6 ) -alkylsulfonyl, amino- (C 1 -C 6 ) -haloalkylsulfonyl, ( C 1 -C 6 -alkylaminosulphonyl, bis [(C 1 -C 6 ) -alkylaminosulphonyl, (C 1 -C 12 -cycloalkylaminosulphonyl, (C 1 -C 6 ) -haloalkylaminosulphonyl, heteroarylaminosulphonyl, arylaminosulphonyl, aryl- (C 1 -C 6 ) -alkylaminosulphonyl, ( C 1 -C 6 ) -alkylsulfonyl, (C 3 -C 6 ) -cycloalkylsulfonyl, arylsulfonyl, hydroxycarbonyl, (C 1 -C 6 ) -alkoxycarbonyl, (C 1 -C 6 -cycloalkoxycarbonyl, (C 3 -C 6 ) -cycloalkyl- (C 1 -C 4 -cyclo), ) - alkoxycarbonyl, aryloxycarbonyl, aryl- (C 1 -C 6) -alkoxycarbonyl, (C 2 -C 6) -alkenyloxycarbonyl, (C 2 -C 6) -alkynyloxycarbonyl, aminocarbonyl, (d-Ce) -alkylaminocarbonyl, bis [(Ci-C 6) - alkyl] aminocarbonyl, (d-Ce) - alkyl [(Ci -Cö) -alkyl] aminocarbonyl, (C 1 -C 6 ) -alkyl [(C 1 -C 6 ) -alkoxy] aminocarbonyl, (C 2 -C 6 ) -alkenylaminocarbonyl, (C 2 -C 6 ) -cycloalkylaminocarbonyL arylaminocarbonyl, aryl- (C 1 -C 6 ) - are alkylaminocarbonyl,
A1, A2, A3 und A4 gleich oder verschieden sind und unabhängig voneinander für N (Stickstoff) oder die Gruppierungen C-H, C-CH3, C-F, C-Cl, C-Br, C-l, C-OCF3, C-OCH3, C-CF3. C-CO2H, C-CO2CH3 stehen, wobei jedoch in keinem Fall mehr als zwei N -Atome benachbart sind, A 1 , A 2 , A 3 and A 4 are the same or different and are each independently N (nitrogen) or the groupings CH, C-CH 3 , CF, C-Cl, C-Br, Cl, C-OCF 3, C -OCH3, C-CF 3. C-CO2H, C-CO2CH3, but in no case more than two N atoms are adjacent,
R17 und R18 unabhängig voneinander für Wasserstoff, Fluor, Chlor, Brom, lod, (Ci-C6)-Alkyl, gegebenenfalls substituiertes Phenyl, Heteroaryl, R 17 and R 18 independently of one another represent hydrogen, fluorine, chlorine, bromine, iodine, (C 1 -C 6) -alkyl, optionally substituted phenyl, heteroaryl,
Heterocyclyl, (C3-C6)-Cycloalkyl, (C2-C6)-Alkenyl, (C2-C6)-Alkinyl, (d-C6)- Alkoxy, (Ci-C6)-Alkoxy-(Ci-C6)-alkyl, Aryloxy-(Ci-C6)-alkyl, (d-C6)- Haloalkoxy, (Ci-C6)-Haloalkyl, (Ci-C6)-Haloalkoxy-(Ci-C6)-alkyl, (d-C6)- Alkoxy-(Ci-C6)-haloalkyl, (Ci-C6)-Haloalkoxy-(Ci-C6)-haloalkyl, (Ci-C6)- Alkylthio, (d-C6)-Haloalkylthio, (d-C6)-Alkylthio-(Ci-C6)-alkyl, Hydroxycarbonyl, (Ci-C-6)-Alkoxycarbonyl, (C3-C-6)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(CrC6)-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-Ce)- al koxycarbonyl , (C2-C6)-Alkenyloxycarbonyl , (C2-Ce)-Al ki nyloxycarbonyl , Aminocarbonyl, (Ci-C6)-Alkylaminocarbonyl, Bis[(d-C6)- alkyl]aminocarbonyl, (Ci-C6)-Alkyl[(Ci-C6)-Alkyl]aminocarbonyl, (d-Co)- Alkyl[(Ci-C6)-Alkoxy]aminocarbonyl, (C2-C6)-Alkenylaminocarbonyl, Heterocyclyl, (C 3 -C 6) -cycloalkyl, (C 2 -C 6) alkenyl, (C 2 -C 6) -alkynyl, (dC 6) - alkoxy, (Ci-C 6) alkoxy (C -C 6) alkyl, aryloxy (Ci-C 6) alkyl, (dC 6) - haloalkoxy, (Ci-C 6) -haloalkyl, (Ci-C 6) haloalkoxy (Ci-C 6) - alkyl, (dC 6) - alkoxy- (Ci-C 6) -haloalkyl, (Ci-C6) haloalkoxy (Ci-C 6) -haloalkyl, (Ci-C 6) - alkylthio, (dC 6) haloalkylthio , (C 1 -C 6 ) -alkylthio (C 1 -C 6 ) -alkyl, Hydroxycarbonyl, (C 1 -C 6) -alkoxycarbonyl, (C 3 -C 6) -cycloalkoxycarbonyl, (C 3 -C 6) -cycloalkyl- (C 1 -C 6) -alkoxycarbonyl, aryloxycarbonyl, aryl- (C 1 -C 6) -alkoxycarbonyl, ( C 2 -C 6) -alkenyloxycarbonyl, (C 2 -C 6) -alkyloxycarbonyl, aminocarbonyl, (C 1 -C 6) -alkylaminocarbonyl, bis [(C 1 -C 6) -alkyl] aminocarbonyl, (C 1 -C 6) -alkyl [( C 6) -alkyl] aminocarbonyl, (d-Co) -alkyl [(C 1 -C 6) -alkoxy] -aminocarbonyl, (C 2 -C 6) -alkenylaminocarbonyl,
(Ca-Cr -Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-Ce)- alkylaminocarbonyl stehen,  (C 1 -C 6 -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 6) -alkylaminocarbonyl,
A5 für S (Schwefel), O (Sauerstoff) oder die Gruppierungen N-H, N-CH3, N- CH2CH3, N-CH(CH3)2, N-C02t-Bu, N-Aryl, N-Heteroaryl, N-Heterocyclyl steht, A 5 represents S (sulfur), O (oxygen) or the groupings NH, N-CH 3 , N-CH 2 CH 3 , N-CH (CH 3 ) 2 , N-CO 2 t-Bu, N-aryl, N-heteroaryl, N-heterocyclyl is
R19, R20, R23 und R24 unabhängig voneinander für Wasserstoff, (d-CeJ-Alkyl, Fluor, Chlor, Brom, lod, (C3-Ce)-Cycloalkyl, gegebenenfalls substituiertes Phenyl, Heteroaryl, Heterocyclyl, (C2-Ce)-Alkenyl, Aryl-(Ci-C6)-alkyl, (CrCö)-Alkoxy, (Ci-C6)-Alkoxy-(Ci-C6)-alkoxy, (Ci-C6)-Alkoxy-(Ci-C6)- alkyl, Hydroxy, (Ci-C6)-Haloalkyl, (Ci-C6)-Haloalkylthio stehen, R 19 , R 20 , R 23 and R 24 independently of one another represent hydrogen, (C 1 -C 6 -alkyl, fluorine, chlorine, bromine, iodine, (C 3 -C 6) -cycloalkyl, optionally substituted phenyl, heteroaryl, heterocyclyl, Ce) alkenyl, aryl (Ci-C6) alkyl, (CrCö) alkoxy, (Ci-C6) alkoxy (Ci-C 6) alkoxy, (Ci-C 6) alkoxy (C -C 6 ) -alkyl, hydroxy, (C 1 -C 6 ) -haloalkyl, (C 1 -C 6 ) -haloalkylthio,
R19 und R23 mit den Atomen, an die sie gebunden sind, einen vollständig R 19 and R 23 with the atoms to which they are attached, a complete
gesättigten oder teilgesättigten, gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden,  form a saturated or partially saturated, optionally further substituted 5 to 7-membered ring,
A6, A7 gleich oder verschieden sind und unabhängig voneinander für O A 6 , A 7 are the same or different and are each independently O.
(Sauerstoff), S (Schwefel), N-H, N-OCH3, N-CH3 oder die Gruppierung CR21 R22 stehen, wobei jedoch in keinem Fall zwei N-, O- oder S-Atome benachbart sind, und wobei R21 und R22 in der Gruppierung CR21 R22 jeweils gleiche oder verschiedene Bedeutungen gemäß der (Oxygen), S (sulfur), NH, N-OCH3, N-CH 3 or the group CR 21 R 22, but in no case two N, O or S atoms are adjacent, and wherein R 21 and R 22 in the group CR 21 R 22 each have the same or different meanings according to the
nachstehenden Definition haben und  have the following definition and
R21 und R22 unabhängig voneinander für Wasserstoff, Fluor, Chlor, Brom, lod, (Ci-Cö)-Alkyl, gegebenenfalls substituiertes Phenyl, Heteroaryl, R 21 and R 22 independently of one another represent hydrogen, fluorine, chlorine, bromine, iodine, (C 1 -C 6) -alkyl, optionally substituted phenyl, heteroaryl,
Heterocyclyl, (C3-C6)-Cycloalkyl, (C2-C6)-Alkenyl, (Ci-C6)-Alkoxy, (Ci-Ce)- Alkoxy-(CrC6)-alkyl, (Ci-C6)-Haloalkoxy, (CrC6)-Haloalkyl, (Ci-C6)- Alkylthio, (Ci-C6)-Haloalkylthio, (Ci-C6)-Alkylihio-(Ci-C6)-alkyl, Heterocyclyl, (C 3 -C 6) -cycloalkyl, (C 2 -C 6) alkenyl, (Ci-C 6) alkoxy, (Ci-Ce) - alkoxy (CrC 6) alkyl, (Ci-C 6 ) -haloalkoxy, (C 1 -C 6 ) -haloalkyl, (C 1 -C 6 ) - Alkylthio, (C 1 -C 6 ) -haloalkylthio, (C 1 -C 6 ) -alkylihio (C 1 -C 6 ) -alkyl,
Hydroxycarbonyl, (CrCt -Alkoxycarbonyl, (C C6)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci-C6)-alkoxycarbonyl, Aryloxycarbonyl, AryKd-Ce)- alkoxycarbonyl, (C2-C6)-Alkenyloxycarbonyl, (C2-C6)-Alkinyloxycarbonyl, Aminocarbonyl, (Ci-C6)-Alkylaminocarbonyl, Bis[(d-C6)- alkyl]aminocarbonyl, (Ci-C6)-Alkyl[(CrC6)-Alkyl]aminocarbonyl, (Ci-Ce)- Alkyl[(Ci-C6)-Alkoxy]aminocarbonyl, (C2-C6)-Alkenylaminocarbonyl,  Hydroxycarbonyl, (C 1 -C 4 -alkoxycarbonyl, C 1 -C 6 -cycloalkoxycarbonyl, C 3 -C 6 -cycloalkyl- (C 1 -C 6) -alkoxycarbonyl, aryloxycarbonyl, AryKd-Ce) -alkoxycarbonyl, (C 2 -C 6) -alkenyloxycarbonyl, (C 2 -C 6) -cycloalkoxycarbonyl C6) -alkynyloxycarbonyl, aminocarbonyl, (C 1 -C 6) -alkylaminocarbonyl, bis [(C 1 -C 6) -alkyl] aminocarbonyl, (C 1 -C 6) -alkyl [(C 1 -C 6) -alkyl] aminocarbonyl, (C 1 -C 6) -alkyl [(C 1 -C 6) -alkoxy] aminocarbonyl, (C 2 -C 6) -alkenylaminocarbonyl,
(Ca-Ce Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-CG)- alkylaminocarbonyl, Amino, (Ci-C6)-Alkylamino, (C3-C6)-Cycloalkylamino, Bis-[(Ci-C6)-Alkyl]amino stehen,  (C 1 -C 6 -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 4) -alkylaminocarbonyl, amino, (C 1 -C 6) -alkylamino, (C 3 -C 6) -cycloalkylamino, bis [(C 1 -C 6) -alkyl] -amino,
R25, R26, R28 und R29 unabhängig voneinander für Wasserstoff, (d-CeJ-Alkyl,R 25 , R 26 , R 28 and R 29 independently of one another represent hydrogen, (d-CeJ-alkyl,
Fluor, Chlor, Brom, lod, (Ca-CeJ-Cycloalkyl, Aryl, Heteroaryl, Heterocyclyl, (C2-C6)-Alkenyl, Aryl-(CrC6)-alkyl, (Ci-Ce)-Alkoxy, (CrC6)-Haloalkyl stehen. Fluorine, chlorine, bromine, iodine, (Ca-CeJ-cycloalkyl, aryl, heteroaryl, heterocyclyl, (C 2 -C 6) alkenyl, aryl (CrC 6) alkyl, (Ci-Ce) alkoxy, (CrC 6 ) -haloalkyl.
A8 für O (Sauerstoff), S (Schwefel), N-H, N-CH3, N-OCH3 oder die Gruppierung CHR27 steht und wobei R27 in der Gruppierung CHR27 die Bedeutung gemäß der nachstehenden Definition hat, A 8 is O (oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the moiety CHR 27 , and wherein R 27 in the moiety CHR 27 has the meaning as defined below,
R27 für Wasserstoff, Fluor, Chlor, Brom, lod, (Ci-Ce)-Alkyl, gegebenenfalls R 27 is hydrogen, fluorine, chlorine, bromine, iodine, (C 1 -C 6) -alkyl, if appropriate
substituiertes Phenyl, Heteroaryl, Heterocyclyl, (C3-C6)-Cycloalkyl, (C2-C6)-Alkenyl, (CrC6)-Alkoxy, (CrC6)-Haloalkoxy, (CrC6)-Haloalkyl, (CrC6)-Alkylthio, (CrC6)-Haloalkylthio, Hydroxycarbonyl, (Ci-C6)- Alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, Aryl-(Ci-Ce)- alkoxycarbonyl , (C2-C6)-Alkenyloxycarbonyi , (C2-C6)-Ai ki nyloxycarbonyl , Aminocarbonyl, (Ci-C6)-Alkylaminocarbonyl, Bis[(Ci-Ce)- alkyljaminocarbonyl, (Ci-C6)-Alkyl[(Ci-C6)-Alkyl]aminocarbonyl, (Ci-Cr>)- Alkyl[(Ci-C6)-Alkoxy]aminocarbonyl, (C2-C6)-Alkenylaminocarbonyl, substituted phenyl, heteroaryl, heterocyclyl, (C3-C6) cycloalkyl, (C 2 -C 6) alkenyl, (CrC 6) alkoxy, (CrC 6) -haloalkoxy, (CrC 6) -haloalkyl, (CrC 6) Alkylthio, (C 1 -C 6 ) -haloalkylthio, hydroxycarbonyl, (C 1 -C 6 ) -alkoxycarbonyl, (C 3 -C 6 ) -cycloalkoxycarbonyl, aryl- (C 1 -C 6 ) -alkoxycarbonyl, (C 2 -C 6 ) -alkenyloxycarbonyl, (C 2 -C 6 ) -alkenyloxycarbonyl, C6) -aryl ki nyloxycarbonyl, aminocarbonyl, (Ci-C6) alkylaminocarbonyl, bis [(Ci-Ce) - alkyljaminocarbonyl, (Ci-C6) alkyl [(Ci-C6) alkyl] aminocarbonyl, (Ci-Cr> ) - alkyl [(C 1 -C 6) -alkoxy] -aminocarbonyl, (C 2 -C 6) -alkenylaminocarbonyl,
(C3-C6)-Cycloalkylaminocarbonyl, Arylaminocarbonyl, Aryl-(Ci-Ce)- alkylaminocarbonyl, Amino, (Ci-CeJ-Alkylamino, (C: C6)-Cycloalkylamino, Bis-[(CrC6)-Alkyl]amino steht, R30, R31, R32, R34, R35 und R36 unabhängig voneinander für Wasserstoff, (d-C-e)- Alkyl, Halogen, (C3-C6)-Cycloalkyl, Aryl, Heteroaryl, Heterocyclyl, (C2-Ce)- Alkenyl, (C,-C6)-Alkoxy, (CrC6)-Haloalkyl, (CrC6)-Alkylthio, (Ci-C6)- Haloalkylthio stehen, (C 3 -C 6) -cycloalkylaminocarbonyl, arylaminocarbonyl, aryl- (C 1 -C 6 ) -alkylaminocarbonyl, amino, (C 1 -C 6 -alkylamino, (C: C 6 ) -cycloalkylamino, bis - [(C 1 -C 6 ) -alkyl] -amino, R 30 , R 31 , R 32 , R 34 , R 35 and R 36 independently of one another represent hydrogen, (C 1 -C 4) -alkyl, halogen, (C 3 -C 6) -cycloalkyl, aryl, heteroaryl, heterocyclyl, (C 2 -C 6) - alkenyl, (C, -C 6) alkoxy, (CrC 6) -haloalkyl, (CrC 6) alkylthio, (Ci-C 6) - haloalkylthio stand,
A9 für O (Sauerstoff), S (Schwefel), N-H, N-CH3, N-OCH3 oder die Gruppierung CHR33 steht und wobei R33 in der Gruppierung CHR33 die Bedeutung gemäß der nachstehenden Definition hat und A 9 is O (oxygen), S (sulfur), NH, N-CH 3 , N-OCH 3 or the group CHR 33 and wherein R 33 in the group CHR 33 has the meaning as defined below and
R33 für Wasserstoff, Fluor, Chlor, Brom, lod, (Ci-Ce)- Alkyl, gegebenenfalls R 33 is hydrogen, fluorine, chlorine, bromine, iodine, (Ci-Ce) - alkyl, optionally
substituiertes Phenyl, Heteroaryl, Heterocyclyl, (C3-C6)-Cycloalkyl, substituted phenyl, heteroaryl, heterocyclyl, (C 3 -C 6) -cycloalkyl,
(C2-C6)-Alkenyl, (Ci-Ce)-Alkoxy, (Ci-C6)-Alkoxy-(Ci-C6)-alkyl, (Ci-Ce)- Haloalkoxy, (Ci-C6)-Haloalkyl, (Ci-Ce)-Alkylthio, (Ci-Ce)-Haloalkylthio, Hydroxycarbonyl, (Ci-CeJ-Alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, Aryl-(d-C6)-alkoxycarbonyl, (C2-C6)-Alkenyloxycarbonyl, (C2-Ce)- Alkinyloxycarbonyl, Aminocarbonyl, (CrCeJ-Alkylaminocarbonyl, (C 2 -C 6) alkenyl, (Ci-Ce) alkoxy, (Ci-C6) alkoxy (Ci-C 6) alkyl, (Ci-Ce) - haloalkoxy, (Ci-C 6) Haloalkyl, (C 1 -C 6) -alkylthio, (C 1 -C 6) -haloalkylthio, hydroxycarbonyl, (C 1 -C 6 -alkoxycarbonyl, (C 3 -C 6) -cycloalkoxycarbonyl, aryl- (C 1 -C 6) -alkoxycarbonyl, (C 2 -C 6) -cycloalkyl) C6) alkenyloxycarbonyl, (C2-Ce) alkynyloxycarbonyl, aminocarbonyl, (CrCeJ-alkylaminocarbonyl,
Bis[(Ci-C6)-alkyl]aminocarbonyl, (Ci-C6)-Alkyl[(Ci-C6)- Alkyl]aminocarbonyl, (Ci-C6)-Alkyl[(CrC6)-Alkoxy]aminocarbonyl, (C2-C6)-Alkenylaminocarbonyl, (Cs-Ce Cycloalkylaminocarbonyl, Bis [(C 1 -C 6 ) -alkyl] aminocarbonyl, (C 1 -C 6 ) -alkyl [(C 1 -C 6 ) -alkyl] aminocarbonyl, (C 1 -C 6 ) -alkyl [(C 1 -C 6) -alkoxy] -aminocarbonyl, ( C 2 -C 6) alkenylaminocarbonyl, (C 3 -C 6 cycloalkylaminocarbonyl,
Arylaminocarbonyl, Aryl-(Ci-C6)-alkylaminocarbonyl, Amino, (d-Ce)- Alkylamino, (C3-C6)-Cycloalkylamino, Bis-[(Ci-C6)-Alkyl]amino steht, Arylaminocarbonyl, aryl- (C 1 -C 6) -alkylaminocarbonyl, amino, (C 1 -C 6) -alkylamino, (C 3 -C 6) -cycloalkylamino, bis- [(C 1 -C 6) -alkyl] -amino,
R37 für (Ci-Ce)-Alkyl, gegebenenfalls substituiertes Phenyl, Heteroaryl, R 37 is (C 1 -C 6) -alkyl, optionally substituted phenyl, heteroaryl,
Heterocyclyl, (C3-C6)-Cycloalkyl, (C2-C6)-Alkenyl, (CrC6)-Alkoxy, (d-Ce)- Alkoxy-(Ci-Ce)-alkyl, Aryloxy-(Ci-Ce)-alkyl, (Ci-C-6)-Alkoxycarbonyl, (C3-C6)- Cycloalkoxycarbonyl, Aryl-(Ci-Cc>)-alkoxycarbonyl, (C2-Cc,)- Alkenyloxycarbonyl, (C2-C6)-Alkinyloxycarbonyl, (Ci-CeJ-Alkylcarbonyl, (C3-C6)-Cycloalkylcarbonyl, Arylcarbonyl, Heteroarylcarbonyl steht. Heterocyclyl, (C 3 -C 6) -cycloalkyl, (C 2 -C 6) alkenyl, (CrC 6) alkoxy, (d-Ce) - alkoxy- (Ci-Ce) alkyl, aryloxy (Ci- Ce) alkyl, (Ci-C6) alkoxycarbonyl, (C3-C6) - cycloalkoxycarbonyl, aryl (Ci-Cc>) -alkoxycarbonyl, (C2-Cc,) - alkenyloxycarbonyl, (C 2 -C 6) - Alkynyloxycarbonyl, (C 1 -C 6 -alkylcarbonyl, (C 3 -C 6) -cycloalkylcarbonyl, arylcarbonyl, heteroarylcarbonyl.
14. Sprühlösung zur Behandlung von Pflanzen, enthaltend eine zur Steigerung der Widerstandsfähigkeit von Pflanzen gegenüber abioti sehen Stressfaktoren wirksame Menge einer oder mehrerer der substituierten l -(Arylethinyl)-, 1 - (Heteroarylethinyl)-, l-(Heterocyclylethinyl)- und 1 -(Cyloalkenylethinyl)- bicycloalkanole gemäß einem der Ansprüche 12 oder 13. 14. A spray solution for the treatment of plants, comprising an amount of one or more of the substituted 1- (arylethynyl) -, 1- (heteroarylethynyl) -, 1- (heterocyclylethynyl) -, 1- (heteroarylethynyl) -, 1- (heterocyclylethynyl) -, and 1-8 (Cyloalkenylethynyl) bicycloalkanols according to one of Claims 12 or 13.
EP13799047.9A 2012-12-05 2013-12-02 Use of substituted 1-(aryl ethynyl)-, 1-(heteroaryl ethynyl)-, 1-(heterocyclyl ethynyl)- and 1-(cyloalkenyl ethynyl)-bicycloalkanols as active agents against abiotic plant stress Withdrawn EP2928297A1 (en)

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EP13799047.9A EP2928297A1 (en) 2012-12-05 2013-12-02 Use of substituted 1-(aryl ethynyl)-, 1-(heteroaryl ethynyl)-, 1-(heterocyclyl ethynyl)- and 1-(cyloalkenyl ethynyl)-bicycloalkanols as active agents against abiotic plant stress
PCT/EP2013/075267 WO2014086723A1 (en) 2012-12-05 2013-12-02 Use of substituted 1-(aryl ethynyl)-, 1-(heteroaryl ethynyl)-, 1-(heterocyclyl ethynyl)- and 1-(cyloalkenyl ethynyl)-bicycloalkanols as active agents against abiotic plant stress

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