EP2900691A4 - GENERATION OF NEW CELLS BETA OF PANCREAS - Google Patents

GENERATION OF NEW CELLS BETA OF PANCREAS

Info

Publication number
EP2900691A4
EP2900691A4 EP13841793.6A EP13841793A EP2900691A4 EP 2900691 A4 EP2900691 A4 EP 2900691A4 EP 13841793 A EP13841793 A EP 13841793A EP 2900691 A4 EP2900691 A4 EP 2900691A4
Authority
EP
European Patent Office
Prior art keywords
generation
beta cells
pancreatic beta
new pancreatic
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP13841793.6A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP2900691A1 (en
Inventor
Claresa Levetan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/662,245 external-priority patent/US9511110B2/en
Priority claimed from US13/662,209 external-priority patent/US8911776B2/en
Priority claimed from US13/662,253 external-priority patent/US9133440B2/en
Priority claimed from US13/662,232 external-priority patent/US20140120560A1/en
Application filed by Individual filed Critical Individual
Publication of EP2900691A1 publication Critical patent/EP2900691A1/en
Publication of EP2900691A4 publication Critical patent/EP2900691A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/474—Pancreatic thread protein; Reg protein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Emergency Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Transplantation (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Reproductive Health (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
EP13841793.6A 2012-09-27 2013-09-26 GENERATION OF NEW CELLS BETA OF PANCREAS Withdrawn EP2900691A4 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201261706225P 2012-09-27 2012-09-27
US13/662,245 US9511110B2 (en) 2012-09-27 2012-10-26 Generation of new pancreatic beta cells
US13/662,209 US8911776B2 (en) 2012-09-27 2012-10-26 Generation of new pancreatic beta cells
US13/662,253 US9133440B2 (en) 2012-09-27 2012-10-26 Generation of new pancreatic beta cells
US13/662,232 US20140120560A1 (en) 2012-10-26 2012-10-26 Generation of new pancreatic beta cells
PCT/US2013/061947 WO2014052611A1 (en) 2012-09-27 2013-09-26 Generation of new pancreatic beta cells

Publications (2)

Publication Number Publication Date
EP2900691A1 EP2900691A1 (en) 2015-08-05
EP2900691A4 true EP2900691A4 (en) 2016-04-20

Family

ID=50388965

Family Applications (1)

Application Number Title Priority Date Filing Date
EP13841793.6A Withdrawn EP2900691A4 (en) 2012-09-27 2013-09-26 GENERATION OF NEW CELLS BETA OF PANCREAS

Country Status (5)

Country Link
EP (1) EP2900691A4 (enExample)
JP (1) JP2015533821A (enExample)
AU (1) AU2013323462A1 (enExample)
CA (1) CA2886442A1 (enExample)
WO (1) WO2014052611A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104614523B (zh) * 2014-12-19 2016-09-21 成都永安制药有限公司 结核分枝杆菌tb-sa抗体酶联免疫法检测试剂盒及其制备方法
WO2017063657A1 (en) * 2015-10-14 2017-04-20 Phlogo Aps Il1ra-derived peptide antagonist
US20190142901A1 (en) * 2017-11-16 2019-05-16 Claresa Levetan Compositions and methods for treating or preventing type 1 diabetes using a biologic response modifier in combination with one or more islet or beta cell regeneration or replacement therapies

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009029847A1 (en) * 2007-08-30 2009-03-05 Curedm, Inc. Compositions and methods of using proislet peptides and analogs thereof
WO2009049222A1 (en) * 2007-10-12 2009-04-16 Curedm, Inc. Compositions and methods of using the human proislet peptide receptor
EP2295066A1 (en) * 2005-05-25 2011-03-16 CureDM Group Holdings, LLC Peptides, derivatives and analogs thereof, and methods of using same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5834590A (en) * 1995-02-22 1998-11-10 Eastern Virginia Medical School Of The Medical College Of Hampton Roads Ingap protein involved in pancreatic islet neogenesis
JP2002525126A (ja) * 1998-09-17 2002-08-13 ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク Ｔｒａｆ相互作用ｅｘｔ遺伝子ファミリーの新規遺伝子ｔｒｅｘ、並びにその診断及び治療への使用
US20040132644A1 (en) * 2001-10-16 2004-07-08 The Procter & Gamble Company Composition and method for treating diabetes

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2295066A1 (en) * 2005-05-25 2011-03-16 CureDM Group Holdings, LLC Peptides, derivatives and analogs thereof, and methods of using same
WO2009029847A1 (en) * 2007-08-30 2009-03-05 Curedm, Inc. Compositions and methods of using proislet peptides and analogs thereof
WO2009049222A1 (en) * 2007-10-12 2009-04-16 Curedm, Inc. Compositions and methods of using the human proislet peptide receptor

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
LEVETAN CLARESA S ET AL: "Discovery of a human peptide sequence signaling islet neogenesis", ENDOCRINE PRACTICE, AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGY, US, vol. 14HIP derived from human Reg3a : 14 aa long : IGL, no. 9, 1 December 2008 (2008-12-01), pages 1075 - 1083, XP002513221, ISSN: 1530-891X *
RAHUL KAPUR ET AL: "Short-term effects of INGAP and Reg family peptides on the appearance of samll beta-cells clusters in non-diabetic mice", ISLETS, vol. 4, no. 1, 1 January 2012 (2012-01-01), pages 40 - 48, XP002755391, DOI: 10.4161/isl.18659 *
ROSENBERG L ET AL: "A pentadecapeptide fragment of islet neogenesis-associated protein increases beta-cell mass and reverses diabetes in C57BL/6J mice", ANNALS OF SURGERY, J.B. LIPPINCOTT COMPANY, PHILADELPHIA, US, vol. 240, 1 January 2004 (2004-01-01), pages 875 - 884, XP002419918, ISSN: 0003-4932, DOI: 10.1097/01.SLA.0000143270.99191.10 *
See also references of WO2014052611A1 *

Also Published As

Publication number Publication date
CA2886442A1 (en) 2014-04-03
JP2015533821A (ja) 2015-11-26
WO2014052611A1 (en) 2014-04-03
AU2013323462A1 (en) 2015-04-23
EP2900691A1 (en) 2015-08-05

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Legal Events

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RIC1 Information provided on ipc code assigned before grant

Ipc: C07K 19/00 20060101ALI20160314BHEP

Ipc: G01N 33/53 20060101ALI20160314BHEP

Ipc: A61K 38/17 20060101ALI20160314BHEP

Ipc: C07K 16/28 20060101ALI20160314BHEP

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