EP2833961A1 - Electrode cuffs - Google Patents
Electrode cuffsInfo
- Publication number
- EP2833961A1 EP2833961A1 EP13773069.3A EP13773069A EP2833961A1 EP 2833961 A1 EP2833961 A1 EP 2833961A1 EP 13773069 A EP13773069 A EP 13773069A EP 2833961 A1 EP2833961 A1 EP 2833961A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- housing
- axis
- shaped
- cuff
- edges
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0551—Spinal or peripheral nerve electrodes
- A61N1/0556—Cuff electrodes
Definitions
- the present invention relates generally to electrical stimulation of tissue, and specifically to methods and devices for regulating the stimulation of nerves or other tissue.
- a number of patents and articles describe methods and devices for stimulating nerves to achieve a desired effect. Often these techniques include a design for an electrode or electrode cuff.
- an electrode assembly comprises a cuff and one or more electrodes.
- the cuff comprises an electrically-insulating material, and is shaped so as to define a tubular housing.
- the housing is shaped so as to define two edges and a longitudinal slit between the two edges. The slit and edges extend along an entire length of the cuff.
- the housing is configured to assume (a) an open position, in which the two edges do not touch each other, and (b) a closed position, in which (i) respective contact surfaces of the two edges touch each other, and (ii) the housing defines an inner surface that faces and surrounds a longitudinal axis of the housing.
- the electrodes are fixed to the inner surface.
- the cuff is shaped so as to define three or more annular insulating elements that extend toward the axis from the inner surface of the housing at respective longitudinal positions along housing.
- the inner surface and pairs of the insulating elements are shaped so as to define, at respective longitudinal positions along the housing, respective chambers open toward the axis.
- one or more of the electrodes are fixed within respective ones of chambers.
- the contact surfaces of the two edges extend toward the axis and protrude into the chambers. This configuration provides greater surface contact between the contact surfaces than if the contact surfaces did not extend into the chambers. This greater surface contact causes the contact surfaces to form a better electrical seal with each other, thereby reducing current leakage from the cuff.
- At least one of the electrodes comprises a strip of metal foil having two end portions and a central portion between the end portions.
- the central portion is disposed against the inner surface of the housing such that, when the housing is in the closed position, the central portion forms a partial ring around the axis that defines an exposed, electrically-conductive surface of the central portion, which exposed surface faces the axis.
- At least one of the end portions is shaped so as to define a curved portion that is embedded in and completely surrounded by the insulating material of the cuff, thereby fixing the end portion to the insulating material. This curved portion helps firmly secure the electrode to the insulating material of the cuff.
- the curved portion has an average radius of curvature that is less than 10% of a length of the central portion measured around axis, such as less than 5%, e.g., less than 3%.
- apparatus including an electrode assembly, which includes:
- a cuff which includes an electrically insulating material, and which is shaped so as to define:
- a tubular housing that defines a longitudinal axis therealong, the housing shaped so as to define two edges and a slit between the two edges, which slit and edges extend along an entire length of the cuff, wherein the housing is configured to assume (a) an open position, in which the two edges do not touch each other, and (b) a closed position, in which (i) respective contact surfaces of the two edges touch each other, and (ii) the housing defines an inner surface that faces and surrounds the axis, to which inner surface the electrodes are fixed, and
- annular insulating elements that extend toward the axis from the inner surface of the housing at respective longitudinal positions along the housing, such that, when the housing is in the closed position, the inner surface of the housing and pairs of the insulating elements are shaped so as to define, at respective longitudinal positions along the housing, respective chambers open toward the axis,
- the housing is shaped such that the contact surfaces of the two edges extend toward the axis and protrude into the chambers.
- the housing is shaped such that the slit and the edges extend parallel to the axis along the entire length of the cuff.
- the cuff is shaped such that the insulating elements and the contact surfaces extend to a same average distance from the axis.
- the cuff is shaped such that a first average distance that the contact surfaces extend from the inner surface toward the axis is less than a second average distance that the insulating elements extend from the inner surface toward the axis.
- the housing is shaped such that an average distance that the first contact surfaces extend from the inner surface toward the axis is at least 0.6 mm.
- the electrodes may be shaped as partial rings, both when the housing is in the open position and when the housing is in the closed position.
- two of the insulating elements may be disposed at respective longitudinal ends of the tubular housing.
- the entire length of the cuff may be between 1 and 40 mm, such as between 5 and 20 mm.
- At least one of the electrodes may be fixed to the inner surface within one of the chambers.
- the cuff may be shaped so as to be placeable around an elliptical cylinder having a major axis that is between 1 and 8 mm and a minor axis that is between 0.5 and 6 mm, and to assume the closed position when thus placed.
- apparatus including an electrode assembly, which includes:
- a cuff which includes an electrically insulating material, and which is shaped so as to define a tubular housing that defines a longitudinal axis therealong, the housing shaped so as to define two edges and a slit between the two edges, which slit and edges extend along an entire length of the cuff, wherein the housing is configured to assume (a) an open position, in which the two edges do not touch each other, and (b) a closed position, in which (i) respective contact surfaces of the two edges touch each other, and (ii) the housing defines an inner surface that faces and surrounds the axis; and
- one or more electrodes at least one of which includes a strip of metal foil having two end portions and a central portion between the end portions,
- central portion is disposed against the inner surface of the housing such that, when the housing is in the closed position, the central portion forms a partial ring around the axis that defines an exposed surface of the central portion, which exposed surface faces the axis, and
- At least one of the end portions is shaped so as to define a curved portion that is embedded in and completely surrounded by the insulating material, thereby fixing the end portion to the insulating material, the curved portion having an average radius of curvature that is less than 10% of a length of the central portion measured around the axis.
- the average radius of curvature of the curved portion is less than 5% of the length of the central portion measured around the axis.
- the housing is shaped such that the slit and the edges extend parallel to the axis along the entire length of the cuff.
- the average radius of curvature of the curved portion may be less than 1.5 mm, such as less than 0.5 mm.
- the strip of metal foil may be shaped such that a direction of curvature of the curved portion is opposite a general direction of curvature of the central portion.
- the curved portion may be shaped so as to define an arc that subtends an angle of at least 90 degrees, such as at least 180 degrees, e.g., at least 270 degrees, such as at least 360 degrees.
- the curved portion, if straightened may have a length of at least 1.5 mm, measured in a direction perpendicular to the axis.
- the curved portion, if straightened may have a length equal to at least 5% of an entire length of the strip of metal, if straightened, which lengths are measured in a direction perpendicular to the axis.
- the at least one of the two end portions may be a first one of the two end portions, the curved portion may be a first curved portion, and a second one of the two end portions may be shaped so as to define a second curved portion that is embedded in and completely surrounded by the insulating material, thereby fixing the second end portion to the insulating material, the second curved portion having an average radius of curvature that is less than 10% of the length of the central portion measured around the axis.
- an electrode assembly that includes (1) one or more electrodes, and (2) a cuff, which includes an electrically insulating material, and which is shaped so as to define (A) a tubular housing that defines a longitudinal axis therealong, the housing shaped so as to define two edges and a slit between the two edges, which slit and edges extend an entire length of the cuff, wherein the housing is configured to assume (a) an open position, in which the two edges do not touch each other, and (b) a closed position, in which (i) respective contact surfaces of the two edges touch each other, and (ii) the housing defines an inner surface that faces and surrounds the axis, to which inner surface the electrodes are fixed, and (B) three or more annular insulating elements that extend toward the axis from the inner surface of the housing at respective longitudinal positions along the housing, such that, when the housing is in the closed position, the inner surface of the housing and pairs of the insulating elements are shaped so as to define, at respective longitudinal positions along the housing
- an electrode assembly that includes (1) a cuff, which includes an electrically insulating material, and which is shaped so as to define a tubular housing that defines a longitudinal axis therealong, the housing shaped so as to define two edges and a slit between the two edges, which slit and edges extend an entire length of the cuff, wherein the housing is configured to assume (a) an open position, in which the two edges do not touch each other, and (b) a closed position, in which (i) respective contact surfaces of the two edges touch each other, and (ii) the housing defines an inner surface that faces and surrounds the axis, and (2) one or more electrodes, at least one of which includes a strip of metal foil having two end portions and a central portion between the end portions, wherein the central portion is disposed against the inner surface of the housing such that, when the housing is in the closed position, the central portion forms a partial ring around the axis that defines an exposed surface of the central portion, which exposed surface faces the axis, and wherein
- FIGS. 1A-C are schematic illustrations of an electrode assembly, in accordance with an application of the present invention
- FIGs. 2A and 2B are schematic illustrations of a cuff of the electrode assembly of
- Figs. 1A-C in slightly open and closed positions, respectively, in accordance with an application of the present invention.
- Fig. 3 is a schematic cut-away illustration of the cuff of Figs. 2A and 2B, in accordance with an application of the present invention.
- Electrode assembly 20 comprises a cuff 24 and one or more electrodes 22.
- electrodes 22 are shown twice in Fig. 1A, both removed from cuff 24 (at the left side of the figure) and disposed within the cuff; in actual practice, the electrodes are disposed within the cuff, as shown at the right side of the figure and in the other figures.
- Fig. 1C is a cut-away illustration of electrode assembly 20, in which a portion of cuff 24 is not shown in order to better illustrate electrodes 22. Electrodes 22 are fixed to cuff 24 such that the electrodes define respective exposed surfaces 26 facing axis 40.
- Cuff 24 is shaped so as to define a tubular housing 28 that defines and at least partially surrounds (typically entirely surrounds) a longitudinal axis 40 therealong.
- Cuff 24 is configured to be placed at least partially around (typically entirely around) a nerve or other tubular body tissue, such as a blood vessel, a muscle, a tendon, a ligament, an esophagus, intestine, a fallopian tube, a neck of a gall bladder, a cystic duct, a hepatic duct, a common hepatic duct, a bile duct, and/or a common bile duct.
- a nerve or other tubular body tissue such as a blood vessel, a muscle, a tendon, a ligament, an esophagus, intestine, a fallopian tube, a neck of a gall bladder, a cystic duct, a hepatic duct, a common hepatic duct, a
- cuff 24 is configured to be placed at least partially around (typically entirely around) an elliptical (e.g., circular) cylinder, which, for example, may have a major axis that is between 1 and 8 mm and a minor axis that is between 0.5 and 6 mm.
- elliptical e.g., circular
- tubular means having the form of an elongated hollow object that defines a conduit therethrough.
- a “tubular” structure may have varied cross-sections therealong, and the cross-sections are not necessarily circular.
- one or more of the cross-sections may be generally circular, or generally elliptical but not circular, circular, or irregularly shaped.
- Cuff 24 comprises an elastic, electrically-insulating material such as silicone or a silicone copolymer, which may have, for example, a hardness of between about 10 Shore A and about 90 Shore A, such as about 40 Shore A.
- cuff 24 comprises more than one material; for example, housing 28 and insulating elements 50, described hereinbelow, may comprise different materials, e.g., may comprise silicone having different hardnesses.
- Electrode assembly 20 optionally further comprises a lead assembly, which comprises one or more electrical leads, as is known in the art.
- the lead assembly may be implemented as described in US Application 12/952,058, filed November 22, 2010, which is assigned to the assignee of the present application and is incorporated herein by reference.
- the leads are coupled to all or a portion of electrodes 22.
- the lead assembly couples electrode assembly 20 to an implanted or external control unit, which comprises appropriate circuitry for driving current between two or more of electrodes 22, as is known in the art.
- the control unit configures the current such that one or more of the contact surfaces function as cathodes, and one or more function as anodes, such as described hereinbelow with reference to Tables 1 and 2.
- FIGs. 2A and 2B are schematic illustrations of cuff 24 in slightly open and closed positions, respectively, in accordance with an application of the present invention.
- Housing 28 is shaped so as to define two edges 30A and 30B and a longitudinal slit 42 between the two edges. The slit and edges extend along an entire length of the cuff 24, typically parallel to axis 40.
- the housing is configured to assume:
- the cuff is placed around the tubular body tissue (such as a nerve) or elliptical cylinder (such as described above) by passing the tubular body tissue or cylinder through the slit when the housing is in the open position. The edges of the slit are brought together to bring the housing into the closed position.
- tubular body tissue such as a nerve
- elliptical cylinder such as described above
- Electrodes 22 are fixed to inner surface 34. Typically, electrodes 22 are shaped as partial rings, both when the housing is in the open position and when the housing is in the closed position. For some applications, electrodes 22 comprise respective strips of metal foil 60, such as described hereinbelow with reference to Figs. 1A-C and 2A-B.
- electrode assembly 20 further comprises one or more closing elements 44, which are configured to hold edges 30A and 30B together.
- each of the closing elements comprises an opening 46 near one edge 30A (labeled in Fig. 3) and a corresponding protrusion 48 on other edge 30B. To close the cuff, each of the protrusions is inserted into the corresponding slit.
- each of the closing elements further comprises a tab 49, which the surgeon implanting the cuff may grasp to help pull protrusion 48 through opening 46.
- FIG. 1C and 2A-B is a schematic cut-away illustration of cuff 24, in accordance with an application of the present invention.
- electrodes 22 are not shown in Fig. 3.
- Cuff 24 is shaped so as to define three or more annular insulating elements 50, which extend toward axis 40 from inner surface 34 of housing 28 at respective longitudinal positions along housing 28.
- cuff 24 is shaped so as to define seven annular insulating elements 50, two of which are disposed at respective longitudinal ends of the cuff, and five of which are disposed longitudinally within the cuff.
- inner surface 34 and pairs of insulating elements 50 are shaped so as to define, at respective longitudinal positions along housing 28, respective chambers 52 open toward axis 40.
- a longitudinal portion of cuff 24 has been cut away in order to show the inside of a longitudinal portion of one of chambers 52.
- cuff 24 is shaped so as to define six annular chambers 52.
- one or more of electrodes 22 are fixed within respective ones of chambers 52, typically to inner surface 34.
- each of chambers 52 has a longitudinal length along the cuff of at least 0.3 mm, no more than 5 mm, and/or between 0.3 and 5 mm.
- housing 28 and insulating elements 50 are molded as a single piece that is shaped so as to define the housing and the insulating elements.
- the insulating elements are fabricated as separate pieces and subsequently affixed to the housing.
- housing 28 is shaped such that contact surfaces 32A and 32B of two edges 30A and 30B extend toward axis 40 and protrude into chambers 52. Respective portions of the material of the housing define two protrusions 36A and 36B, which extend toward the axis and protrude into the chambers, and which define the portions of contact surfaces 32A and 32B, respectively, that extend toward the axis and protrude into the chambers.
- This configuration provides greater surface contact between contact surfaces 32A and 32B than if the contact surfaces did not extend into the chambers. This greater surface contact causes the contact surfaces to form a better electrical seal with each other, thereby reducing current leakage from the cuff.
- Contact surfaces 32A and 32B extend radially inward to an average distance Dl from axis 40.
- average distance Dl is at least 0.5 mm, no more than 3 mm, and/or between 0.5 and 3 mm, such as at least 1.1 mm, no more than 1.8 mm, and/or between 1.1 and 1.8 mm.
- Insulating elements 50 extend radially inward to an average distance D2 from axis 40.
- average distance D2 is at least 0.5 mm, no more than 3 mm, and/or between 0.5 and 3 mm, such as at least 1.1 mm, no more than 1.8 mm, and/or between 1.1 and 1.8 mm.
- average distance D2 is less for the insulating elements at the longitudinal ends of the cuff than for the insulating elements disposed longitudinally within the cuff.
- average distance Dl equals average distance D2; in other words, insulating elements 50 and contact surfaces 32A and 32B extend to a same average distance from axis 40.
- protrusions 36A and 36B define surfaces 38A and 38B, respectively, which face axis 40; surfaces 38A and 38B may have the same curvature as the surfaces of insulating elements 50 that face the axis, such as shown in Fig. 2A.
- Contact surfaces 32A and 32B extend radially inward a first average distance D3 from inner surface 34 toward axis 40.
- average distance D3 is at least 0.1 mm, no more than 3 mm, and/or between 0.1 and 3 mm, such as at least 0.3 mm, no more than 1.5 mm, and/or between 0.3 and 1.5 mm.
- Insulating elements 50 extend radially inward a second average distance D4 from inner surface 34 toward axis 40.
- average distance D4 is at least 0.1 mm, no more than 3 mm, and/or between 0.1 and 3 mm, such as at least 0.3 mm, no more than 1.5 mm, and/or between 0.3 and 1.5 mm.
- first average distance D3 is less than second average distance D4.
- Each of protrusions 36A and 36B has a width W, measured in a direction perpendicular to both (a) axis 40 and (b) contact surfaces 32A and 32B, respectively, when cuff 24 is in the closed position.
- width W is at least 0.3 mm, no more than 2 mm, and/or between 0.3 and 2 mm.
- an entire length LI of cuff 24, measured along longitudinal axis 40 is at least 1 mm, no more than 40 mm, and/or between 1 and 40 mm, e.g., at least 5 mm, no more than 20 mm, and/or between 5 and 20 mm, such as 12 mm.
- At least one of electrodes 22 comprises strip of metal foil 60, which has two end portions 62A and 62B and a central portion 64 between the end portions.
- Central portion 64 is disposed against inner surface 34 of housing 28 such that, when the housing is in the closed position, the central portion forms a partial ring around axis 40 that defines exposed, electrically-conductive surface 26 of the central portion, which exposed surface 26 faces the axis (exposed surfaces 26 of the electrodes are shaded in the figures).
- the ring is not necessarily partially or entirely curved (as shown in the figures), and may optionally include one or more straight portions.
- all of the electrodes comprise respective strips of metal foil 60.
- end portions 62A and 62B is shaped so as to define a curved portion 70 that is embedded in and completely surrounded by the insulating material of cuff 24, thereby fixing the end portion to the insulating material.
- This curved portion helps firmly secure the electrode to the insulating material of the cuff by enforcing the mechanical connection between the electrode and the insulating material.
- curved portion 70 has an average radius of curvature R that is less than 10% of a length L2 of central portion 64 measured around axis 40, such as less than 5%, e.g., less than 3%.
- both of end portions 62A and 62B comprise respective curved portions 70 having the characteristics described herein.
- length L2 "measured around the axis" is to be understood as the length of central portion 64 measured in a direction perpendicular to axis 40, if the central portion were to be flattened, i.e., unrolled. This length may also be considered the "circumferential" length of central portion 64, even though central portion 64 typically does not form a complete loop, such as a complete ellipse or circle.
- average radius of curvature R is less than 1.5 mm, e.g., less than 1 mm, such as less than 0.5 mm, and/or at least 0.2 mm, e.g., between 0.25 mm and 0.5 mm, such as 0.25 mm or 0.35 mm.
- length L2 is at least 10 mm, no more than 20 mm, and/or between 10 mm and 20 mm, such as about 14 mm.
- strip of metal foil 60 is shaped such that a direction of curvature of curved portion 70 is opposite a general direction of curvature of central portion 64.
- a general direction of curvature of central portion 64 as approaching end portion 62B is counterclockwise, which transitions to clockwise along curved portion 70 of end portion 62B.
- curved portion 70 is shaped so as to define an arc that subtends an angle of at least 90 degrees, such as at least 180 degrees, at least 270 degrees, or at least 360 degrees. (In the figures, curved portion 70 is shows subtending an angle of slightly greater than 360 degrees, i.e., a full circle with slightly overlapping end portions.) For some applications, curved portion 70, if straightened, would have a length of at least 1.5 mm, measured in a direction perpendicular to axis 40.
- curved portion 70 if straightened, would have a length equal to at least 5% of an entire length of the strip of metal foil 60, if straightened, which lengths are measured in a direction perpendicular to axis 40.
- one or more of electrodes 22 are fixed within respective ones of chambers 52.
- the following tables set forth two exemplary distributions of the electrodes in the chambers.
- the tables also indicate, by way of example, which of the electrodes are configured by a control unit to function as cathode(s), which as anode(s), and which as passive electrode(s).
- Each of the passive electrodes is coupled to at least one other passive electrode, and is electrically device- coupled to neither (a) any circuitry that is electrically device-coupled to at least one cathode or at least one anode, nor (b) an energy source.
- the passive electrodes may be implemented using techniques described in US Patent 7,627,384 to Ayal et al., which is incorporated herein by reference.
- the chambers are numbered from left to right in Figs. 1A and 1C. TABLE 1
- Patent 7,778,703 ⁇ US Patent Application 10/205,474, filed July 24, 2002, which issued as US
Landscapes
- Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Electrotherapy Devices (AREA)
Abstract
Description
Claims
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN1023DE2012 IN2012DE01023A (en) | 2012-04-02 | 2012-04-02 | |
US13/437,114 US8880192B2 (en) | 2012-04-02 | 2012-04-02 | Electrode cuffs |
PCT/IL2013/050286 WO2013150524A1 (en) | 2012-04-02 | 2013-03-21 | Electrode cuffs |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2833961A1 true EP2833961A1 (en) | 2015-02-11 |
EP2833961A4 EP2833961A4 (en) | 2015-11-25 |
Family
ID=49300086
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP13773069.3A Withdrawn EP2833961A4 (en) | 2012-04-02 | 2013-03-21 | Electrode cuffs |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP2833961A4 (en) |
CN (1) | CN104582787A (en) |
WO (1) | WO2013150524A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102014014927A1 (en) * | 2014-10-07 | 2016-04-07 | Neuroloop GmbH | Implantable electrode arrangement |
DE102018207709A1 (en) | 2018-05-17 | 2019-11-21 | Neuroloop GmbH | Device for extravascular or extraneuronal attachment of a medical implant in the form of a winding cuff |
AU2019445979A1 (en) * | 2019-05-16 | 2021-12-23 | Board Of Regents, The University Of Texas System | Devices and methods for neuromodulation |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3421511A (en) * | 1965-12-10 | 1969-01-14 | Medtronic Inc | Implantable electrode for nerve stimulation |
US5344438A (en) * | 1993-04-16 | 1994-09-06 | Medtronic, Inc. | Cuff electrode |
DE4433111A1 (en) * | 1994-09-16 | 1996-03-21 | Fraunhofer Ges Forschung | Cuff electrode |
US5531778A (en) * | 1994-09-20 | 1996-07-02 | Cyberonics, Inc. | Circumneural electrode assembly |
US6600956B2 (en) * | 2001-08-21 | 2003-07-29 | Cyberonics, Inc. | Circumneural electrode assembly |
US20100010603A1 (en) * | 2008-07-09 | 2010-01-14 | Tamir Ben-David | Electrode cuffs |
US8718791B2 (en) * | 2003-05-23 | 2014-05-06 | Bio Control Medical (B.C.M.) Ltd. | Electrode cuffs |
EP3527255B1 (en) * | 2006-10-13 | 2020-08-05 | Cyberonics, Inc. | Obstructive sleep apnea treatment devices and systems |
US7996092B2 (en) * | 2007-01-16 | 2011-08-09 | Ndi Medical, Inc. | Devices, systems, and methods employing a molded nerve cuff electrode |
US20110160827A1 (en) * | 2008-05-02 | 2011-06-30 | Medtronic. Inc. | Electrode lead system |
-
2013
- 2013-03-21 WO PCT/IL2013/050286 patent/WO2013150524A1/en active Application Filing
- 2013-03-21 CN CN201380028300.4A patent/CN104582787A/en active Pending
- 2013-03-21 EP EP13773069.3A patent/EP2833961A4/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
WO2013150524A1 (en) | 2013-10-10 |
EP2833961A4 (en) | 2015-11-25 |
CN104582787A (en) | 2015-04-29 |
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