EP2825201A4 - The filamentous bacteriophage as an angiogenesis modulator - Google Patents

The filamentous bacteriophage as an angiogenesis modulator

Info

Publication number
EP2825201A4
EP2825201A4 EP13761938.3A EP13761938A EP2825201A4 EP 2825201 A4 EP2825201 A4 EP 2825201A4 EP 13761938 A EP13761938 A EP 13761938A EP 2825201 A4 EP2825201 A4 EP 2825201A4
Authority
EP
European Patent Office
Prior art keywords
filamentous bacteriophage
angiogenesis modulator
angiogenesis
modulator
filamentous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP13761938.3A
Other languages
German (de)
French (fr)
Other versions
EP2825201A1 (en
Inventor
Beka Solomon
Eyal Dor-On
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ramot at Tel Aviv University Ltd
Original Assignee
Ramot at Tel Aviv University Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ramot at Tel Aviv University Ltd filed Critical Ramot at Tel Aviv University Ltd
Publication of EP2825201A1 publication Critical patent/EP2825201A1/en
Publication of EP2825201A4 publication Critical patent/EP2825201A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/14011—Details ssDNA Bacteriophages
    • C12N2795/14111—Inoviridae
    • C12N2795/14122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/14011—Details ssDNA Bacteriophages
    • C12N2795/14111—Inoviridae
    • C12N2795/14132—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/14011—Details ssDNA Bacteriophages
    • C12N2795/14111—Inoviridae
    • C12N2795/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2795/14145—Special targeting system for viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/14011—Details ssDNA Bacteriophages
    • C12N2795/14111—Inoviridae
    • C12N2795/14151—Methods of production or purification of viral material
EP13761938.3A 2012-03-15 2013-03-15 The filamentous bacteriophage as an angiogenesis modulator Withdrawn EP2825201A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261611297P 2012-03-15 2012-03-15
US201261715634P 2012-10-18 2012-10-18
PCT/US2013/032043 WO2013138716A1 (en) 2012-03-15 2013-03-15 The filamentous bacteriophage as an angiogenesis modulator

Publications (2)

Publication Number Publication Date
EP2825201A1 EP2825201A1 (en) 2015-01-21
EP2825201A4 true EP2825201A4 (en) 2015-12-09

Family

ID=49161851

Family Applications (1)

Application Number Title Priority Date Filing Date
EP13761938.3A Withdrawn EP2825201A4 (en) 2012-03-15 2013-03-15 The filamentous bacteriophage as an angiogenesis modulator

Country Status (2)

Country Link
EP (1) EP2825201A4 (en)
WO (1) WO2013138716A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT201700009270A1 (en) * 2017-01-27 2018-07-27 Consiglio Naz Delle Ricerche Cnr Phagic conjugates and their uses
EP4038183A1 (en) * 2019-10-01 2022-08-10 Adaptive Phage Therapeutics, Inc. Method for purification of bacteriophage particles

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7867487B2 (en) * 2005-02-01 2011-01-11 Ramot At Tel-Aviv University Ltd. Method for treating inflammation associated with amyloid deposits and brain inflammation involving activated microglia
WO2006095345A2 (en) * 2005-03-08 2006-09-14 Ramot At Tel-Aviv University Ltd. Targeted drug-carrying bacteriophages
US20070098828A1 (en) * 2005-11-01 2007-05-03 Gonzalez-Villasenor Lucia I Methods and compositions for the prevention and regression of neovascularization
CA2642473A1 (en) * 2006-02-15 2007-08-23 Ramot At Tel Aviv University Filamentous bacteriophage displaying protein as a binder of antibodies and immunocomplexes for delivery to the brain
GB0703369D0 (en) * 2007-02-21 2007-03-28 Health Prot Agency Compositions Comprising Capsular Polysaccharides and Their Use as Vaccines

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
BORATYNSKI JANUSZ ET AL: "Preparation of endotoxin-free bacteriophages", CELLULAR & MOLECULAR BIOLOGY LETTERS, UNIVERSITY OF WROCAW. INSTITUTE OF BIOCHEMISTRY, WROCAW; PL, PL, vol. 9, no. 2, 1 January 2004 (2004-01-01), pages 253 - 259, XP002485107, ISSN: 1425-8153 *
DABROWSKA K ET AL: "Activity of bacteriophages in murine tumor models depends on the route of phage administration", ONCOLOGY RESEARCH, PERGAMON PRESS, NEW YORK, NY, US, vol. 15, no. 4, 1 January 2005 (2005-01-01), pages 183 - 187, XP008120418, ISSN: 0965-0407 *
DABROWSKA KRYSTYNA ET AL: "The effect of bacteriophages T4 and HAP1 on in vitro melanoma migration", BMC MICROBIOLOGY, BIOMED CENTRAL LTD, GB, vol. 9, no. 1, 20 January 2009 (2009-01-20), pages 13, XP021048179, ISSN: 1471-2180, DOI: 10.1186/1471-2180-9-13 *
JESSICA I. LUNDIN ET AL: "Endotoxin and Cancer", ENVIRONMENTAL HEALTH PERSPECTIVES SUPPLEMENTS, vol. 117, no. 9, 1 September 2009 (2009-09-01), US, pages 1344 - 1350, XP055221367, ISSN: 1078-0475, DOI: 10.1289/ehp.0800439 *
PAULINA BUDYNEK ET AL: "Bacteriophages and cancer", ARCHIVES OF MICROBIOLOGY, SPRINGER, BERLIN, DE, vol. 192, no. 5, 16 March 2010 (2010-03-16), pages 315 - 320, XP019798350, ISSN: 1432-072X *
See also references of WO2013138716A1 *
TOURNAIRE R ET AL: "A short synthetic peptide inhibits signal transduction, migration and angiogenesis mediated by Tie2 receptor", EMBO REPORTS, vol. 5, no. 3, 1 January 2004 (2004-01-01), pages 262 - 267, XP002321017, DOI: 10.1038/SJ.EMBOR.7400100 *

Also Published As

Publication number Publication date
WO2013138716A1 (en) 2013-09-19
EP2825201A1 (en) 2015-01-21

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Ipc: C12N 7/00 20060101ALI20151102BHEP

Ipc: A61K 39/395 20060101AFI20151102BHEP

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Ipc: A61K 35/76 20150101ALI20151102BHEP

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