EP2773739B1 - A liquid hard surface antimicrobial cleaning composition - Google Patents
A liquid hard surface antimicrobial cleaning composition Download PDFInfo
- Publication number
- EP2773739B1 EP2773739B1 EP12769078.2A EP12769078A EP2773739B1 EP 2773739 B1 EP2773739 B1 EP 2773739B1 EP 12769078 A EP12769078 A EP 12769078A EP 2773739 B1 EP2773739 B1 EP 2773739B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- composition
- weight
- hard surface
- terpineol
- thymol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000000203 mixture Substances 0.000 title claims description 77
- 230000000845 anti-microbial effect Effects 0.000 title claims description 28
- 238000004140 cleaning Methods 0.000 title claims description 17
- 239000007788 liquid Substances 0.000 title claims description 12
- MGSRCZKZVOBKFT-UHFFFAOYSA-N thymol Chemical compound CC(C)C1=CC=C(C)C=C1O MGSRCZKZVOBKFT-UHFFFAOYSA-N 0.000 claims description 38
- SQIFACVGCPWBQZ-UHFFFAOYSA-N delta-terpineol Natural products CC(C)(O)C1CCC(=C)CC1 SQIFACVGCPWBQZ-UHFFFAOYSA-N 0.000 claims description 20
- 229940116411 terpineol Drugs 0.000 claims description 20
- 239000005844 Thymol Substances 0.000 claims description 19
- WUOACPNHFRMFPN-UHFFFAOYSA-N alpha-terpineol Chemical compound CC1=CCC(C(C)(C)O)CC1 WUOACPNHFRMFPN-UHFFFAOYSA-N 0.000 claims description 19
- 229960000790 thymol Drugs 0.000 claims description 19
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims description 10
- 150000003839 salts Chemical class 0.000 claims description 10
- 230000000249 desinfective effect Effects 0.000 claims description 9
- 239000000341 volatile oil Substances 0.000 claims description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 9
- 229960000686 benzalkonium chloride Drugs 0.000 claims description 8
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 claims description 8
- 235000019832 sodium triphosphate Nutrition 0.000 claims description 8
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 6
- 239000002736 nonionic surfactant Substances 0.000 claims description 6
- 239000003795 chemical substances by application Substances 0.000 claims description 5
- 238000000034 method Methods 0.000 claims description 5
- 229910000029 sodium carbonate Inorganic materials 0.000 claims description 5
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 claims description 4
- 229940049920 malate Drugs 0.000 claims description 4
- BJEPYKJPYRNKOW-UHFFFAOYSA-N malic acid Chemical compound OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 claims description 4
- XNGIFLGASWRNHJ-UHFFFAOYSA-L phthalate(2-) Chemical compound [O-]C(=O)C1=CC=CC=C1C([O-])=O XNGIFLGASWRNHJ-UHFFFAOYSA-L 0.000 claims description 4
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims description 4
- OFOBLEOULBTSOW-UHFFFAOYSA-L Malonate Chemical compound [O-]C(=O)CC([O-])=O OFOBLEOULBTSOW-UHFFFAOYSA-L 0.000 claims description 3
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 claims description 3
- 150000002191 fatty alcohols Chemical class 0.000 claims description 3
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 claims description 2
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 claims description 2
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 claims description 2
- 150000003628 tricarboxylic acids Chemical class 0.000 claims 3
- 230000000844 anti-bacterial effect Effects 0.000 description 10
- 241000894006 Bacteria Species 0.000 description 7
- 210000001541 thymus gland Anatomy 0.000 description 7
- 150000003627 tricarboxylic acid derivatives Chemical class 0.000 description 7
- 150000007942 carboxylates Chemical class 0.000 description 6
- 239000004615 ingredient Substances 0.000 description 6
- 239000004094 surface-active agent Substances 0.000 description 6
- 239000001509 sodium citrate Substances 0.000 description 5
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 5
- 238000004659 sterilization and disinfection Methods 0.000 description 5
- 238000010790 dilution Methods 0.000 description 4
- 239000012895 dilution Substances 0.000 description 4
- -1 malonte Chemical compound 0.000 description 4
- PRWXGRGLHYDWPS-UHFFFAOYSA-L sodium malonate Chemical compound [Na+].[Na+].[O-]C(=O)CC([O-])=O PRWXGRGLHYDWPS-UHFFFAOYSA-L 0.000 description 4
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 3
- 108091003079 Bovine Serum Albumin Proteins 0.000 description 3
- 241000246358 Thymus Species 0.000 description 3
- 235000007303 Thymus vulgaris Nutrition 0.000 description 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 3
- 229940098773 bovine serum albumin Drugs 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 229910052760 oxygen Inorganic materials 0.000 description 3
- 239000001301 oxygen Substances 0.000 description 3
- 239000002689 soil Substances 0.000 description 3
- 239000001585 thymus vulgaris Substances 0.000 description 3
- WUOACPNHFRMFPN-SECBINFHSA-N (S)-(-)-alpha-terpineol Chemical compound CC1=CC[C@@H](C(C)(C)O)CC1 WUOACPNHFRMFPN-SECBINFHSA-N 0.000 description 2
- 241001103617 Pseudomonas aeruginosa ATCC 15442 Species 0.000 description 2
- 240000002657 Thymus vulgaris Species 0.000 description 2
- 229910052783 alkali metal Inorganic materials 0.000 description 2
- OVKDFILSBMEKLT-UHFFFAOYSA-N alpha-Terpineol Natural products CC(=C)C1(O)CCC(C)=CC1 OVKDFILSBMEKLT-UHFFFAOYSA-N 0.000 description 2
- 229940088601 alpha-terpineol Drugs 0.000 description 2
- 150000001735 carboxylic acids Chemical class 0.000 description 2
- 239000003093 cationic surfactant Substances 0.000 description 2
- 239000002738 chelating agent Substances 0.000 description 2
- NNRLDGQZIVUQTE-UHFFFAOYSA-N gamma-Terpineol Chemical compound CC(C)=C1CCC(C)(O)CC1 NNRLDGQZIVUQTE-UHFFFAOYSA-N 0.000 description 2
- 229910052736 halogen Inorganic materials 0.000 description 2
- 150000002367 halogens Chemical class 0.000 description 2
- 239000008233 hard water Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000007800 oxidant agent Substances 0.000 description 2
- 235000013824 polyphenols Nutrition 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 230000002195 synergetic effect Effects 0.000 description 2
- 239000010678 thyme oil Substances 0.000 description 2
- RUJPNZNXGCHGID-UHFFFAOYSA-N (Z)-beta-Terpineol Natural products CC(=C)C1CCC(C)(O)CC1 RUJPNZNXGCHGID-UHFFFAOYSA-N 0.000 description 1
- 229920001817 Agar Polymers 0.000 description 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 description 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical group C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 description 1
- 239000001744 Sodium fumarate Substances 0.000 description 1
- 240000006219 Thymus mastichina Species 0.000 description 1
- 235000007236 Thymus mastichina Nutrition 0.000 description 1
- 240000006001 Thymus serpyllum Species 0.000 description 1
- 235000004054 Thymus serpyllum Nutrition 0.000 description 1
- 241001184553 Thymus x citriodorus Species 0.000 description 1
- 244000157222 Thymus zygis Species 0.000 description 1
- 235000017826 Thymus zygis Nutrition 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 150000001340 alkali metals Chemical class 0.000 description 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 description 1
- 239000004599 antimicrobial Substances 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 description 1
- 229910052794 bromium Inorganic materials 0.000 description 1
- HHTWOMMSBMNRKP-UHFFFAOYSA-N carvacrol Natural products CC(=C)C1=CC=C(C)C(O)=C1 HHTWOMMSBMNRKP-UHFFFAOYSA-N 0.000 description 1
- RECUKUPTGUEGMW-UHFFFAOYSA-N carvacrol Chemical compound CC(C)C1=CC=C(C)C(O)=C1 RECUKUPTGUEGMW-UHFFFAOYSA-N 0.000 description 1
- 235000007746 carvacrol Nutrition 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 210000002421 cell wall Anatomy 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- WPUMTJGUQUYPIV-JIZZDEOASA-L disodium (S)-malate Chemical compound [Na+].[Na+].[O-]C(=O)[C@@H](O)CC([O-])=O WPUMTJGUQUYPIV-JIZZDEOASA-L 0.000 description 1
- HQWKKEIVHQXCPI-UHFFFAOYSA-L disodium;phthalate Chemical compound [Na+].[Na+].[O-]C(=O)C1=CC=CC=C1C([O-])=O HQWKKEIVHQXCPI-UHFFFAOYSA-L 0.000 description 1
- 239000003974 emollient agent Substances 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- 229940050411 fumarate Drugs 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 239000003349 gelling agent Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- WYXXLXHHWYNKJF-UHFFFAOYSA-N isocarvacrol Natural products CC(C)C1=CC=C(O)C(C)=C1 WYXXLXHHWYNKJF-UHFFFAOYSA-N 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 239000010665 pine oil Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 238000007747 plating Methods 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 238000011012 sanitization Methods 0.000 description 1
- 235000019265 sodium DL-malate Nutrition 0.000 description 1
- 229940005573 sodium fumarate Drugs 0.000 description 1
- 235000019294 sodium fumarate Nutrition 0.000 description 1
- 239000001394 sodium malate Substances 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000000475 sunscreen effect Effects 0.000 description 1
- 239000000516 sunscreening agent Substances 0.000 description 1
- 239000011885 synergistic combination Substances 0.000 description 1
- QJVXKWHHAMZTBY-GCPOEHJPSA-N syringin Chemical compound COC1=CC(\C=C\CO)=CC(OC)=C1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 QJVXKWHHAMZTBY-GCPOEHJPSA-N 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/20—Organic compounds containing oxygen
- C11D3/2003—Alcohols; Phenols
- C11D3/2006—Monohydric alcohols
- C11D3/2037—Terpenes
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/20—Organic compounds containing oxygen
- C11D3/2075—Carboxylic acids-salts thereof
- C11D3/2082—Polycarboxylic acids-salts thereof
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/26—Organic compounds containing nitrogen
- C11D3/30—Amines; Substituted amines ; Quaternized amines
Definitions
- the invention relates to a liquid hard surface cleaning and disinfection composition.
- the invention more particularly relates to a hard surface disinfection composition that provides synergistic antibacterial efficacy.
- Liquid compositions for disinfecting and cleaning hard surfaces like floors, walls, windows, doors, furniture, and table tops in various indoor and outdoor locations are known. Toilets and bathrooms are other places where germs proliferate and disinfection and cleaning compositions in liquid form are widely used. Other types of hard surfaces that are cleaned by such compositions include utensils and other articles found in households, offices and other public places.
- halogen and active oxygen are two most effective bleaches.
- Bleaches are compounds that liberate oxidising agents like chlorine, bromine, fluorine, nascent oxygen or other oxidizing agents that break the cell walls of microbes like bacteria and virus thereby disinfecting the surfaces thus treated.
- Phenolics are another class of antimicrobials often derived from essential oils extracted from natural sources which are formulated in an emulsified form and sold as floor and toilet cleaners.
- these compounds are sometimes considered either harsh or take a long time for the antimicrobial action to take place.
- these compositions include surfactants to either emulsify the oily components present therein or to enable cleaning via detergency action or both. To remove the residual surfactants the surfaces being treated or cleaned are soon thereafter rinsed or wiped to be substantially free of the disinfection/ cleaning composition. This allows very little time for the disinfection action to take place.
- the present inventors have found that inclusion of benzalkonium chloride and selected salts of di or tricarboxylic acid when combined with thymol or terpineol provides similar synergistic antimicrobial action in a rapid fashion and such efficacy is obtained at much lower concentrations of thymol and/ or terpineol.
- This invention has the advantage that essential oil actives like terpineol and thymol have a strong medicinal odour which is not liked by some consumers and it is advantageous to include thymol and terpineol at lower concentrations while ensuring that same efficient anti-microbial action. Further, it has been found by way of the present invention that inclusion of a chelating agent sodium tripolyphosphate provides for further enhanced antibacterial efficacy.
- Liquid hard surface cleaning compositions having a pH 9 to 12 comprising cationic surfactant are known.
- US6048836 (1998 , P&G) discloses the use, in a composition, of a combination of a chelating agent, a surfactant, and an essential oil or an active thereof, to provide disinfecting properties.
- Another object of the present invention is to provide a liquid hard surface cleaning and disinfecting composition that has relatively fast antimicrobial action.
- a liquid hard surface antimicrobial cleaning composition with a pH in the range of 9 to 12 comprising
- a method of cleaning and disinfecting a hard surface comprising applying to said hard surface a composition of the first aspect diluted with water in a weight ratio of 1: 20 to 1: 200.
- the first aspect of the invention provides for a liquid hard surface antimicrobial cleaning composition with a pH in the range of 9 to 12.
- the composition comprises 0.5 to 4% by weight of benzalkonium chloride; 0.25 to 3% by weight of salt of di or tri carboxylic acid; 0.01 to 2% by weight of an essential oil active selected from thymol or terpineol; and 87 to 97% by weight water.
- the composition comprises 0.5 to 4%, more preferably 1 to 2%, further more preferably 1.25 to 1.75% cationic surfactant benzalkonium chloride.
- the composition comprises 0.25 to 3%, preferably 0.5 to 2%, more preferably 0.5 to 1.5% by weight of the composition salt of di or tri carboxylic acid.
- the salt of di or tri carboxylic acid is preferably chosen from an oxalate, fumarate, phthalate, maleate, malate, malonate or citrate.
- the salt of di or tricarboxylic acid is most preferably a phthalate, malate, malonte, or citrate.
- Alkali metal or alkaline earth metal salts are preferred, more preferably alkali metal salts of which sodium salt is most preferred. Structure of salts of some of the carboxylic acids are given below:
- the composition comprises an essential oil antimicrobial active selected from thymol or terpineol at 0.01 to 2% by weight of the composition.
- Preferred antimicrobial compositions of the present invention have thymol higher than 0.05 and lesser than 0.3% by weight. Thymol may be added to the antimicrobial composition in purified form. Alternatively, thyme oil or thyme extract comprising thymol may be added to the antimicrobial composition, while ensuring that thymol is present in the desired concentration in the composition of the present invention. Thyme oil or thyme extract is obtained from the thyme plant.
- Thyme plant refers to a plant belonging be genus Thymus and includes but is not limited to the following species: Thymus vulgaris, Thymus zygis, Thymus satureoides, Thymus mastichina, Thymus broussonetti, Thymus maroccanus, Thymus pallidus, Thymus algeriensis, Thymus serpyllum, Thymus pulegoide, and Thymus citriodorus.
- Preferred antimicrobial compositions of the present invention have terpineol higher than 0.05 and lesser than 1% by weight.
- the terpineol is preferably selected from alpha-terpineol, beta-terpineol, gamma-terpineol or mixtures thereof. It is particularly preferred that the terpineol is alpha-terpineol.
- Terpineol may be added to the antimicrobial composition in purified form. Alternatively pine oil comprising terpineol may be added to the antimicrobial composition.
- the composition optionally comprises sodium tripoly phosphate (STPP).
- STPP sodium tripoly phosphate
- composition of the invention comprises water as a preferred carrier. Water is present in 87 to 97%, preferably 90 to 95% by weight of the composition.
- a composition of the invention optionally comprises a surfactant.
- Preferred surfactant is a non-ionic surfactant.
- Non-ionic surfactant is preferably present in an amount of 2 to 10% by weight of the composition.
- Particularly preferred nonionic surfactants are fatty alcohol ethoxylates preferably C8-C22, more preferably C8-C16 fatty alcohol ethoxylates, comprising between 1 and 8 ethylene oxide groups.
- Suitable surfactant concentrations in liquid form of hard surface cleaning compositions are preferably from 1 to 5 % by weight of the composition.
- the composition of the invention has pH in the range of 9 to 12, preferably in the range of 10.5 to 11.5. This could be achieved by incorporating the essential ingredients of the invention in selected amounts, else may be achieved by incorporating an alkaline agent.
- the alkaline agent is preferably sodium carbonate or sodium hydroxide.
- the alkaline agent is preferably present in 0.1 to 1% by weight of the composition.
- the present inventors have determined that the highly efficacious antimicrobial action of the composition of the invention can be achieved in the absence of conventional disinfectants like bleaches e.g. halogens, halogenated compounds and active oxygen based bleaches.
- bleaches e.g. halogens, halogenated compounds and active oxygen based bleaches.
- small amount of such bleaches may be present in the composition e.g. less than 1%, preferably less than 0.5%, more preferably less than 0.1% and the efficacy of the composition is achievable even with the bleaches being absent from the composition.
- composition may further comprise various additional ingredients known to a person skilled in the art.
- additional ingredients include but are not limited to: perfumes, pigments, preservatives, emollients, sunscreens, emulsifiers, gelling agents, or thickening agents.
- the antimicrobial composition may be in form of a liquid but the liquid composition may be further thickened to a gel or a paste.
- the antimicrobial composition of the present invention can be used for cleansing and care of hard surfaces such as glass, metal, plastic, wood, ceramic and the like.
- a method of cleaning and disinfecting a hard surface comprising applying to said hard surface a composition of the invention diluted with water in a weight ratio of 1: 20 to 1: 200, preferably in a ratio of 1:40 to 1:80.
- the method preferably comprises a step of rinsing the surface with a suitable solvent preferably water or the surface may be wiped with a suitable wipe.
- composition of the invention provides an antimicrobial action where the contact time of the antimicrobial actives with the surface is low, i.e. of the order of less than 5 minutes, preferably less than 2 minutes, further more preferably less than a minute and in many cases less than 15 seconds.
- Antibacterial compositions for hard surface cleaning as shown in Table - 1 read along with Table - 2 were prepared.
- the compositions were tested for antibacterial efficacy using the European Suspension Test BS EN1276 which is briefly described below:
- Table - 1 Ingredients Weight% Neodol (C12E09) 3.0 Benzalkonium chloride 1.5 Essential oil active As shown in Table - 2 Sodium Carbonate 0.3 Di/tri carboxylate (as shown in Table 2) 1.0 Table - 2: Compositions as per Table - 1 where prepared using the di/carboxylic acids and thymol and/or terpineol concentrations as shown below: Example Di/tri carboxylic acid Thymol (wt%) Terpineol (wt%) Log reduction Example 1 - - - 3.2 Example 2 - 0.125 - 3.1 Example 3 Sodium malonate 0.125 - 6.4 Example 4 Sodium citrate 0.125 - 7.3 Example 5 - - 0.25 3.0 Example 6 Sodium malonate - 0.25 5.2 Example 7 Sodium citrate - 0.25 7.3 Example 8 - 0.125 0.25 3.3 Example 9 Sodium malonate 0.125 0.25 6.8 Example 10 Sodium citrate 0.125 0.25 7.3
- compositions as per the invention (Examples 3,4,6,7,9,10) provide for vastly superior antibacterial efficacy as compared to compositions outside the invention (Examples 1,2,5,8).
- Table 3 indicates that the antibacterial compositions of the invention (Examples 12and 13) are effective even at short contact times of about 30 seconds.
- compositions as shown in Table - 4 were tested for antibacterial efficacy at a dilution of 1:60 with hard water at a contact time of 5 minutes.
- the soil was BSA at 0.3%.
- the bacteria used was P. aeruginosa ATCC 15442 (at 10 7 cfu/ml cell density).
- the pH of the compositions were 11. The data is shown in Table - 4.
- Example 14 (wt%) Example 15 (wt%) Example 16 (wt%) Example 17 (wt%) Example 18 (wt%) Example 19 (wt%) Neodol (C12EO9) 3.0 3.0 3.0 3.0 3.0 3.0 Benzalkonium chloride 1.5 1.5 1.5 1.5 1.5 1.5 Sodium Carbonate 0.3 0.3 0.3 0.3 0.3 Di / tri carboxylate - Sodium fumarate 1.0 Sodium phthalate 1.0 Sodium malate 1.0 Sodium malonate 1.0 Sodium citrate 1.0 Thymol 0.125 0.125 0.125 0.125 0.125 0.125 0.125 Terpineol 0.25 0.25 0.25 0.25 0.25 0.25 0.25 Log reduction of bacteria 4.3 5.2 7.3 5.9 7.3 7.3 *STPP: is sodium tripolyphosphate
Description
- The invention relates to a liquid hard surface cleaning and disinfection composition. The invention more particularly relates to a hard surface disinfection composition that provides synergistic antibacterial efficacy.
- Liquid compositions for disinfecting and cleaning hard surfaces like floors, walls, windows, doors, furniture, and table tops in various indoor and outdoor locations are known. Toilets and bathrooms are other places where germs proliferate and disinfection and cleaning compositions in liquid form are widely used. Other types of hard surfaces that are cleaned by such compositions include utensils and other articles found in households, offices and other public places.
- Two of the popular classes of disinfecting / sanitizing actives are (i) bleaches and (ii) phenolics. Halogen and active oxygen are two most effective bleaches. Bleaches are compounds that liberate oxidising agents like chlorine, bromine, fluorine, nascent oxygen or other oxidizing agents that break the cell walls of microbes like bacteria and virus thereby disinfecting the surfaces thus treated. Phenolics are another class of antimicrobials often derived from essential oils extracted from natural sources which are formulated in an emulsified form and sold as floor and toilet cleaners.
- These compounds are sometimes considered either harsh or take a long time for the antimicrobial action to take place. Very often, these compositions include surfactants to either emulsify the oily components present therein or to enable cleaning via detergency action or both. To remove the residual surfactants the surfaces being treated or cleaned are soon thereafter rinsed or wiped to be substantially free of the disinfection/ cleaning composition. This allows very little time for the disinfection action to take place.
- Therefore, there is a need of providing a composition that gives relatively more efficacious antimicrobial action when cleaning period is relatively small, typically about 5 minutes or less, preferably lesser than 2 minutes and in many cases less than one minute or sometimes as low as 15 seconds or lesser. The present applicants have, in a prior patent application published as
WO2010046238 disclosed a novel combination of thymol and terpineol that interact synergistically to enable fast antimicrobial action in less than about 15 seconds. The present inventors have found that inclusion of benzalkonium chloride and selected salts of di or tricarboxylic acid when combined with thymol or terpineol provides similar synergistic antimicrobial action in a rapid fashion and such efficacy is obtained at much lower concentrations of thymol and/ or terpineol. This invention has the advantage that essential oil actives like terpineol and thymol have a strong medicinal odour which is not liked by some consumers and it is advantageous to include thymol and terpineol at lower concentrations while ensuring that same efficient anti-microbial action. Further, it has been found by way of the present invention that inclusion of a chelating agent sodium tripolyphosphate provides for further enhanced antibacterial efficacy. - Liquid hard surface cleaning compositions having a pH 9 to 12 comprising cationic surfactant are known.
-
US6048836 (1998 , P&G) discloses the use, in a composition, of a combination of a chelating agent, a surfactant, and an essential oil or an active thereof, to provide disinfecting properties. - The patent publication cited above does not address the problem of slow-acting antimicrobial composition, nor disclose the synergistic combination of actives disclosed and claimed in the present invention for the fast acting antimicrobial action in disinfecting hard surfaces.
US 2009/0105195 also discloses antimicrobial compositions. - It is an object of the present invention to overcome or ameliorate at least one of the disadvantages of the prior art, or to provide a useful alternative.
- Another object of the present invention is to provide a liquid hard surface cleaning and disinfecting composition that has relatively fast antimicrobial action.
- According to the first aspect of the invention there is provided a liquid hard surface antimicrobial cleaning composition with a pH in the range of 9 to 12 comprising
- (a) 0.5 to 4% by weight of benzalkonium chloride;
- (b) 0.25 to 3% by weight of salt of di or tri carboxylic acid;
- (c) 0.01 to 2% by weight an essential oil antimicrobial active selected from thymol or terpineol; and
- (d) 87 to 97% by weight water.
- According to another aspect of the invention there is provided a method of cleaning and disinfecting a hard surface comprising applying to said hard surface a composition of the first aspect diluted with water in a weight ratio of 1: 20 to 1: 200.
- These and other aspects, features and advantages will become apparent to those of ordinary skill in the art from a reading of the following detailed description and the appended claims. For the avoidance of doubt, any feature of one aspect of the present invention may be utilised in any other aspect of the invention. The word "comprising" is intended to mean "including" but not necessarily "consisting of" or "composed of." In other words, the listed steps or options need not be exhaustive. It is noted that the examples given in the description below are intended to clarify the invention and are not intended to limit the invention to those examples per se. Similarly, all percentages are weight/weight percentages unless otherwise indicated.
- Except in the operating and comparative examples, or where otherwise explicitly indicated, all numbers in this description indicating amounts of material or conditions of reaction, physical properties of materials and/or use are to be understood as modified by the word "about". Unless specified otherwise, numerical ranges expressed in the format "from x to y" are understood to include x and y. When for a specific feature multiple preferred ranges are described in the format "from x to y", it is understood that all ranges combining the different endpoints are also contemplated.
- The first aspect of the invention provides for a liquid hard surface antimicrobial cleaning composition with a pH in the range of 9 to 12. The composition comprises 0.5 to 4% by weight of benzalkonium chloride; 0.25 to 3% by weight of salt of di or tri carboxylic acid; 0.01 to 2% by weight of an essential oil active selected from thymol or terpineol; and 87 to 97% by weight water.
- The composition comprises 0.5 to 4%, more preferably 1 to 2%, further more preferably 1.25 to 1.75% cationic surfactant benzalkonium chloride.
- The composition comprises 0.25 to 3%, preferably 0.5 to 2%, more preferably 0.5 to 1.5% by weight of the composition salt of di or tri carboxylic acid. The salt of di or tri carboxylic acid is preferably chosen from an oxalate, fumarate, phthalate, maleate, malate, malonate or citrate. The salt of di or tricarboxylic acid is most preferably a phthalate, malate, malonte, or citrate. Alkali metal or alkaline earth metal salts are preferred, more preferably alkali metal salts of which sodium salt is most preferred. Structure of salts of some of the carboxylic acids are given below:
- It is observed that inclusion of di or tri carboxylates in the composition of the invention provides for the desired antimicrobial efficacy while mono carboxylates do not demonstrate as good an efficacy.
- The composition comprises an essential oil antimicrobial active selected from thymol or terpineol at 0.01 to 2% by weight of the composition.
- Preferred antimicrobial compositions of the present invention have thymol higher than 0.05 and lesser than 0.3% by weight. Thymol may be added to the antimicrobial composition in purified form. Alternatively, thyme oil or thyme extract comprising thymol may be added to the antimicrobial composition, while ensuring that thymol is present in the desired concentration in the composition of the present invention. Thyme oil or thyme extract is obtained from the thyme plant. Thyme plant refers to a plant belonging be genus Thymus and includes but is not limited to the following species: Thymus vulgaris, Thymus zygis, Thymus satureoides, Thymus mastichina, Thymus broussonetti, Thymus maroccanus, Thymus pallidus, Thymus algeriensis, Thymus serpyllum, Thymus pulegoide, and Thymus citriodorus.
-
- Preferred antimicrobial compositions of the present invention have terpineol higher than 0.05 and lesser than 1% by weight. The terpineol is preferably selected from alpha-terpineol, beta-terpineol, gamma-terpineol or mixtures thereof. It is particularly preferred that the terpineol is alpha-terpineol. Terpineol may be added to the antimicrobial composition in purified form. Alternatively pine oil comprising terpineol may be added to the antimicrobial composition.
-
- The composition optionally comprises sodium tripoly phosphate (STPP). When present, STPP is present in 0.25 to 3%, preferably 0.5 to 2%, more preferably 1.25 to 1.75% by weight of the composition.
- The composition of the invention comprises water as a preferred carrier. Water is present in 87 to 97%, preferably 90 to 95% by weight of the composition.
- A composition of the invention optionally comprises a surfactant. Preferred surfactant is a non-ionic surfactant. Non-ionic surfactant is preferably present in an amount of 2 to 10% by weight of the composition. Particularly preferred nonionic surfactants are fatty alcohol ethoxylates preferably C8-C22, more preferably C8-C16 fatty alcohol ethoxylates, comprising between 1 and 8 ethylene oxide groups. Suitable surfactant concentrations in liquid form of hard surface cleaning compositions are preferably from 1 to 5 % by weight of the composition.
- The composition of the invention has pH in the range of 9 to 12, preferably in the range of 10.5 to 11.5. This could be achieved by incorporating the essential ingredients of the invention in selected amounts, else may be achieved by incorporating an alkaline agent. The alkaline agent is preferably sodium carbonate or sodium hydroxide. The alkaline agent is preferably present in 0.1 to 1% by weight of the composition.
- The present inventors have determined that the highly efficacious antimicrobial action of the composition of the invention can be achieved in the absence of conventional disinfectants like bleaches e.g. halogens, halogenated compounds and active oxygen based bleaches. However small amount of such bleaches may be present in the composition e.g. less than 1%, preferably less than 0.5%, more preferably less than 0.1% and the efficacy of the composition is achievable even with the bleaches being absent from the composition.
- The composition may further comprise various additional ingredients known to a person skilled in the art. Such additional ingredients include but are not limited to: perfumes, pigments, preservatives, emollients, sunscreens, emulsifiers, gelling agents, or thickening agents.
- The antimicrobial composition may be in form of a liquid but the liquid composition may be further thickened to a gel or a paste. The antimicrobial composition of the present invention can be used for cleansing and care of hard surfaces such as glass, metal, plastic, wood, ceramic and the like.
- According to another aspect of the present invention there is provided a method of cleaning and disinfecting a hard surface comprising applying to said hard surface a composition of the invention diluted with water in a weight ratio of 1: 20 to 1: 200, preferably in a ratio of 1:40 to 1:80.
- The method preferably comprises a step of rinsing the surface with a suitable solvent preferably water or the surface may be wiped with a suitable wipe.
- The inventors have determined that the composition of the invention provides an antimicrobial action where the contact time of the antimicrobial actives with the surface is low, i.e. of the order of less than 5 minutes, preferably less than 2 minutes, further more preferably less than a minute and in many cases less than 15 seconds.
- The invention will now be illustrated with the help of the following non-limiting examples.
- Antibacterial compositions for hard surface cleaning as shown in Table - 1 read along with Table - 2 were prepared. The compositions were tested for antibacterial efficacy using the European Suspension Test BS EN1276 which is briefly described below:
- A test suspension of bacteria (1 ml) was added to a sample of the product under a certain dilution condition (8 ml) along with a specific soil (1 ml). The mixture was maintained at 20°C for 5 minutes. After this period of contact time, an aliquot was taken and was immediately neutralized by a validated method. The number of bacteria in each sample were determined by plating in TSA agar and the reduction in viable count was calculated after incubating for 48 hours.
- In Table - 1, below the organism used was bacteria P. aeruginosa ATCC 15442 (at 107 cfu/ml concentration); the dilution was 1:60 of the product (a floor cleaner) in hard water. The soil used was used was Bovine Serum Albumin (BSA) at a final concentration of 0.03%. The pH of the samples was 11.0.
Table - 1 Ingredients Weight% Neodol (C12E09) 3.0 Benzalkonium chloride 1.5 Essential oil active As shown in Table - 2 Sodium Carbonate 0.3 Di/tri carboxylate (as shown in Table 2) 1.0 Table - 2: Compositions as per Table - 1 where prepared using the di/carboxylic acids and thymol and/or terpineol concentrations as shown below: Example Di/tri carboxylic acid Thymol (wt%) Terpineol (wt%) Log reduction Example 1 - - - 3.2 Example 2 - 0.125 - 3.1 Example 3 Sodium malonate 0.125 - 6.4 Example 4 Sodium citrate 0.125 - 7.3 Example 5 - - 0.25 3.0 Example 6 Sodium malonate - 0.25 5.2 Example 7 Sodium citrate - 0.25 7.3 Example 8 - 0.125 0.25 3.3 Example 9 Sodium malonate 0.125 0.25 6.8 Example 10 Sodium citrate 0.125 0.25 7.3 - The data in Table 1 and 2 indicates that the compositions as per the invention (Examples 3,4,6,7,9,10) provide for vastly superior antibacterial efficacy as compared to compositions outside the invention (Examples 1,2,5,8).
- Experiments similar to Examples 1 to 10 were carried out except that the dilution was 1:40 and the time of contact of the product with the bacteria was 30 seconds instead of 5 minutes. The data is summarized in Table - 3.
Table - 3: Ingredients Example 11 (wt%) Example 12 (wt%) Example 13 (wt%) Neodol (C12E09) 3.0 3.0 3.0 Benzalkonium chloride 1.5 1.5 1.5 Sodium Carbonate 0.3 0.3 0.3 Di/tri carboxylate - Sodium malonate 1.0 Sodium citrate 1.0 Thymol 0.125 0.125 0.125 Terpineol 0.25 0.25 0.25 Log reduction of bacteria 2.0 5.2 6.8 - The data in Table 3 indicates that the antibacterial compositions of the invention (Examples 12and 13) are effective even at short contact times of about 30 seconds.
- Compositions as shown in Table - 4 were tested for antibacterial efficacy at a dilution of 1:60 with hard water at a contact time of 5 minutes. The soil was BSA at 0.3%. The bacteria used was P. aeruginosa ATCC 15442 (at 107 cfu/ml cell density). The pH of the compositions were 11. The data is shown in Table - 4.
Table -4 Ingredients Example 14 (wt%) Example 15 (wt%) Example 16 (wt%) Example 17 (wt%) Example 18 (wt%) Example 19 (wt%) Neodol (C12EO9) 3.0 3.0 3.0 3.0 3.0 3.0 Benzalkonium chloride 1.5 1.5 1.5 1.5 1.5 1.5 STPP* 1.5 1.5 1.5 1.5 1.5 1.5 Sodium Carbonate 0.3 0.3 0.3 0.3 0.3 0.3 Di / tri carboxylate - Sodium fumarate 1.0 Sodium phthalate 1.0 Sodium malate 1.0 Sodium malonate 1.0 Sodium citrate 1.0 Thymol 0.125 0.125 0.125 0.125 0.125 0.125 Terpineol 0.25 0.25 0.25 0.25 0.25 0.25 Log reduction of bacteria 4.3 5.2 7.3 5.9 7.3 7.3 *STPP: is sodium tripolyphosphate - The data in Table 4 indicates that various other di/tri carboxylates may be used in the composition of the invention in the presence of essential oil actives and these samples (Examples 15 to 19) give vastly superior antibacterial efficacy as compared to a sample outside the invention (Example 14).
Claims (11)
- A liquid hard surface antimicrobial cleaning composition with a pH in the range of 9 to 12 comprising(a) 0.5 to 4% by weight of benzalkonium chloride;(b) 0.25 to 3% by weight of salt of di or tri carboxylic acid;(c) 0.01 to 2% by weight an essential oil antimicrobial active selected from thymol or terpineol; and(d) 87 to 97% by weight water.
- A composition as claimed in claim 1 comprising thymol and terpineol.
- A composition as claimed in claim 1 or 2 wherein said salt of di or tri carboxylic acid is chosen from an oxalate, fumarate, phthalate, maleate, malate, malonate or citrate.
- A composition as claimed in claim 3 wherein said salt of di or tricarboxylic acid is chosen from a phthalate, malate, malonate, or citrate.
- A composition as claimed in any one of the preceding claims comprising 0.25 to 3% sodium tripolyphosphate.
- A composition as claimed in any one of the preceding claims comprising a non-ionic surfactant.
- A composition as claimed in claim 6 wherein said non-ionic surfactant is present in an amount of 2 to 10% by weight of the composition.
- A composition as claimed in claim 6 or 7 wherein said non-ionic surfactant comprises fatty alcohol ethoxylate.
- A composition as claimed in any one of the preceding claims comprising an alkaline agent selected from sodium carbonate or sodium hydroxide.
- A composition as claimed in claim 9 wherein said alkaline agent is present in 0.1 to 1% by weight of the composition.
- A method of cleaning and disinfecting a hard surface comprising applying to said hard surface a composition as claimed in any one of the preceding claims diluted with water in a ratio of 1:20 to 1:200.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL12769078T PL2773739T3 (en) | 2011-11-03 | 2012-09-26 | A liquid hard surface antimicrobial cleaning composition |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN3095MU2011 | 2011-11-03 | ||
PCT/EP2012/068987 WO2013064315A1 (en) | 2011-11-03 | 2012-09-26 | A liquid hard surface antimicrobial cleaning composition |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2773739A1 EP2773739A1 (en) | 2014-09-10 |
EP2773739B1 true EP2773739B1 (en) | 2015-11-04 |
Family
ID=46980938
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP12769078.2A Active EP2773739B1 (en) | 2011-11-03 | 2012-09-26 | A liquid hard surface antimicrobial cleaning composition |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP2773739B1 (en) |
CN (1) | CN103890160B (en) |
BR (1) | BR112014008053B1 (en) |
EA (1) | EA022049B1 (en) |
MX (1) | MX339345B (en) |
PL (1) | PL2773739T3 (en) |
WO (1) | WO2013064315A1 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2023011929A1 (en) | 2021-08-04 | 2023-02-09 | Unilever Ip Holdings B.V. | An antimicrobial bleach composition |
WO2023011953A1 (en) | 2021-08-04 | 2023-02-09 | Unilever Ip Holdings B.V. | A stable bleach composition |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9206381B2 (en) | 2011-09-21 | 2015-12-08 | Ecolab Usa Inc. | Reduced misting alkaline cleaners using elongational viscosity modifiers |
US9309485B2 (en) | 2013-06-26 | 2016-04-12 | Ecolab USA, Inc. | Use of nonionics as rheology modifiers in liquid cleaning solutions |
EP3019009A4 (en) | 2013-08-07 | 2017-01-11 | Sanit Technologies Llc | Antimicrobial sanitizer compositions and methods of making the same |
US9637708B2 (en) | 2014-02-14 | 2017-05-02 | Ecolab Usa Inc. | Reduced misting and clinging chlorine-based hard surface cleaner |
CN108289444B (en) * | 2015-11-27 | 2021-08-27 | 联合利华知识产权控股有限公司 | Antimicrobial compositions |
BR112018073540B1 (en) | 2016-05-19 | 2023-04-25 | Ecolab Usa Inc | METHOD FOR CLEANING A CALCITE STONE SURFACE, COMPOSITION AND USE |
ES2808999T3 (en) | 2016-05-23 | 2021-03-02 | Ecolab Usa Inc | Neutral and alkaline antiseptic and disinfectant cleaning compositions with reduced haze formation through the use of high molecular weight water-in-oil emulsion polymers |
MX2018013936A (en) | 2016-05-23 | 2019-03-28 | Ecolab Usa Inc | Reduced misting acidic cleaning, sanitizing, and disinfecting compositions via the use of high molecular weight water-in-oil emulsion polymers. |
CN106318653A (en) * | 2016-08-19 | 2017-01-11 | 桂林福冈新材料有限公司 | Glass washing agent free of trace after being cleaned |
US11540512B2 (en) | 2017-03-01 | 2023-01-03 | Ecolab Usa Inc. | Reduced inhalation hazard sanitizers and disinfectants via high molecular weight polymers |
DE102017124010A1 (en) * | 2017-10-16 | 2019-04-18 | Oliver Ganzenmüller | Mixture for cleaning surfaces |
JP7170300B2 (en) * | 2017-12-11 | 2022-11-14 | 株式会社ニイタカ | liquid detergent composition |
CN114096650A (en) | 2019-07-12 | 2022-02-25 | 埃科莱布美国股份有限公司 | Alkaline cleaner with reduced fogging using alkali soluble emulsion polymers |
RU2766860C1 (en) * | 2021-04-26 | 2022-03-16 | Общество с ограниченной ответственностью «Синергия Технологий» | Detergent composition |
Citations (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0621335A2 (en) | 1993-04-19 | 1994-10-26 | Reckitt & Colman Inc. | All purpose cleaning composition |
GB2307915A (en) | 1995-11-14 | 1997-06-11 | Reckitt & Colman Inc | Pine oil type cleaning compositions |
GB2322552A (en) | 1997-03-01 | 1998-09-02 | Reckitt & Colman Inc | Liquid disinfectant concentrate |
US6048836A (en) | 1996-07-16 | 2000-04-11 | The Procter & Gamble Company | Use of a combination of surfactants, chelating agents and essential oils for effective disinfection |
WO2000027981A1 (en) | 1998-11-10 | 2000-05-18 | The Procter & Gamble Company | Disinfecting and cleaning compositions |
US6191091B1 (en) | 1997-03-04 | 2001-02-20 | Marcel Raymond | Biodegradable compound for cleaning, disinfecting, and descaling water dispensers and method of use thereof |
US6613728B1 (en) | 1998-06-26 | 2003-09-02 | The Procter & Gamble Company | Use of an anti-microbial compound for disinfection |
WO2009019255A2 (en) | 2007-08-03 | 2009-02-12 | Vetagro S.R.L. | Synergetic composition comprising flavouring substances and organic acids and use thereof |
US20090105195A1 (en) | 2007-10-17 | 2009-04-23 | O'brien Chris | Composition comprising microbicidal active ingredients |
US20090232905A1 (en) | 2006-11-02 | 2009-09-17 | Ohsoclean, Inc. | Essential oils based cleaning and disinfecting compositions |
WO2010046238A1 (en) | 2008-10-20 | 2010-04-29 | Unilever Nv | An antimicrobial composition |
WO2010078883A2 (en) | 2008-12-18 | 2010-07-15 | Bode Chemie Gmbh | Combined disinfection and decontamination agent having increased effectivity |
WO2011002929A1 (en) | 2009-06-30 | 2011-01-06 | The Trustees Of Columbia University In The City Of New York | Antimicrobial/preservative compositions comprising botanicals |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0791362A3 (en) * | 1996-02-23 | 1998-03-04 | The Procter & Gamble Company | Disinfecting compositions and processes for disinfecting surfaces |
GB9704989D0 (en) * | 1997-03-11 | 1997-04-30 | Unilever Plc | Improvements relating to hard-surface cleaning compositions |
CO5040174A1 (en) * | 1997-12-12 | 2001-05-29 | Colgate Palmolive Co | ANTIMICROBIAL COMPOSITIONS FOR MULTIPLE MICROEMULSION PURPOSES CONTAINING A CATIONIC TENSIOACTIVE |
GB2341092B (en) * | 1998-09-07 | 2000-12-06 | Macgregor Keith Martin | Composition for the removal of biological and organic substances |
-
2012
- 2012-09-26 EA EA201400533A patent/EA022049B1/en not_active IP Right Cessation
- 2012-09-26 PL PL12769078T patent/PL2773739T3/en unknown
- 2012-09-26 WO PCT/EP2012/068987 patent/WO2013064315A1/en active Application Filing
- 2012-09-26 EP EP12769078.2A patent/EP2773739B1/en active Active
- 2012-09-26 CN CN201280052095.0A patent/CN103890160B/en active Active
- 2012-09-26 BR BR112014008053-4A patent/BR112014008053B1/en active IP Right Grant
- 2012-09-26 MX MX2014005403A patent/MX339345B/en active IP Right Grant
Patent Citations (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0621335A2 (en) | 1993-04-19 | 1994-10-26 | Reckitt & Colman Inc. | All purpose cleaning composition |
GB2307915A (en) | 1995-11-14 | 1997-06-11 | Reckitt & Colman Inc | Pine oil type cleaning compositions |
US6048836A (en) | 1996-07-16 | 2000-04-11 | The Procter & Gamble Company | Use of a combination of surfactants, chelating agents and essential oils for effective disinfection |
GB2322552A (en) | 1997-03-01 | 1998-09-02 | Reckitt & Colman Inc | Liquid disinfectant concentrate |
US6191091B1 (en) | 1997-03-04 | 2001-02-20 | Marcel Raymond | Biodegradable compound for cleaning, disinfecting, and descaling water dispensers and method of use thereof |
US6613728B1 (en) | 1998-06-26 | 2003-09-02 | The Procter & Gamble Company | Use of an anti-microbial compound for disinfection |
WO2000027981A1 (en) | 1998-11-10 | 2000-05-18 | The Procter & Gamble Company | Disinfecting and cleaning compositions |
US20090232905A1 (en) | 2006-11-02 | 2009-09-17 | Ohsoclean, Inc. | Essential oils based cleaning and disinfecting compositions |
WO2009019255A2 (en) | 2007-08-03 | 2009-02-12 | Vetagro S.R.L. | Synergetic composition comprising flavouring substances and organic acids and use thereof |
US20090105195A1 (en) | 2007-10-17 | 2009-04-23 | O'brien Chris | Composition comprising microbicidal active ingredients |
WO2010046238A1 (en) | 2008-10-20 | 2010-04-29 | Unilever Nv | An antimicrobial composition |
WO2010078883A2 (en) | 2008-12-18 | 2010-07-15 | Bode Chemie Gmbh | Combined disinfection and decontamination agent having increased effectivity |
US20120107415A1 (en) | 2008-12-18 | 2012-05-03 | Thomas Lisowsky | Combined disinfection and decontamination agent having increased effectiveness |
WO2011002929A1 (en) | 2009-06-30 | 2011-01-06 | The Trustees Of Columbia University In The City Of New York | Antimicrobial/preservative compositions comprising botanicals |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2023011929A1 (en) | 2021-08-04 | 2023-02-09 | Unilever Ip Holdings B.V. | An antimicrobial bleach composition |
WO2023011953A1 (en) | 2021-08-04 | 2023-02-09 | Unilever Ip Holdings B.V. | A stable bleach composition |
Also Published As
Publication number | Publication date |
---|---|
MX339345B (en) | 2016-05-20 |
CN103890160B (en) | 2017-03-08 |
BR112014008053A2 (en) | 2017-04-11 |
WO2013064315A1 (en) | 2013-05-10 |
MX2014005403A (en) | 2014-07-11 |
CN103890160A (en) | 2014-06-25 |
BR112014008053B1 (en) | 2021-06-01 |
EA022049B1 (en) | 2015-10-30 |
EA201400533A1 (en) | 2014-08-29 |
EP2773739A1 (en) | 2014-09-10 |
PL2773739T3 (en) | 2016-06-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP2773739B1 (en) | A liquid hard surface antimicrobial cleaning composition | |
EP2338343B1 (en) | Enhanced activity hydrogen peroxide disinfectant | |
US7465697B1 (en) | Essential oils based cleaning and disinfecting compositions | |
EP1423497B1 (en) | Thickened toilet bowl cleaner | |
EP2480090B1 (en) | Disinfecting agent comprising eugenol, terpineol and thymol | |
EP2780438B1 (en) | A liquid hard surface antimicrobial cleaning composition | |
EP2576747B1 (en) | Hard surface treatment composition | |
EP2787956B1 (en) | An anti bacterial composition | |
ZA200207599B (en) | Process of disinfecting a hard-surface with a composition comprising cinnamon oil and/or an active thereof. | |
EP2773315B1 (en) | A personal cleaning composition | |
US9756855B2 (en) | Antimicrobial particle and compositions thereof | |
CN113163751A (en) | Bleaching agent composition | |
JP5188950B2 (en) | Hard surface cleaning and sterilization method | |
WO2023025575A1 (en) | A liquid disinfecting composition | |
EP2759199A1 (en) | A method of providing antimicrobial action and a synergistic antimicrobial composition thereof | |
WO2023219867A1 (en) | Single dose disinfectant | |
JP2008156253A (en) | Mildew-removing, mildew-proofing and bactericidal agent | |
CN111655832A (en) | Mildew-removing cleaning agent composition for hard surface |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20140320 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
DAX | Request for extension of the european patent (deleted) | ||
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
INTG | Intention to grant announced |
Effective date: 20150724 |
|
GRAS | Grant fee paid |
Free format text: ORIGINAL CODE: EPIDOSNIGR3 |
|
GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
AK | Designated contracting states |
Kind code of ref document: B1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: FG4D |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: EP |
|
REG | Reference to a national code |
Ref country code: AT Ref legal event code: REF Ref document number: 759199 Country of ref document: AT Kind code of ref document: T Effective date: 20151115 |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: FG4D |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R096 Ref document number: 602012012209 Country of ref document: DE |
|
REG | Reference to a national code |
Ref country code: NL Ref legal event code: MP Effective date: 20151104 |
|
REG | Reference to a national code |
Ref country code: LT Ref legal event code: MG4D |
|
REG | Reference to a national code |
Ref country code: AT Ref legal event code: MK05 Ref document number: 759199 Country of ref document: AT Kind code of ref document: T Effective date: 20151104 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: NO Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160204 Ref country code: LT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20151104 Ref country code: NL Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20151104 Ref country code: IS Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160304 Ref country code: HR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20151104 Ref country code: ES Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20151104 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: RS Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20151104 Ref country code: FI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20151104 Ref country code: AT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20151104 Ref country code: LV Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20151104 Ref country code: PT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160304 Ref country code: SE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20151104 Ref country code: GR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160205 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: CZ Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20151104 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R026 Ref document number: 602012012209 Country of ref document: DE |
|
PLBI | Opposition filed |
Free format text: ORIGINAL CODE: 0009260 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: RO Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20151104 Ref country code: SM Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20151104 Ref country code: EE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20151104 Ref country code: DK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20151104 Ref country code: SK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20151104 |
|
26 | Opposition filed |
Opponent name: THE PROCTER & GAMBLE COMPANY Effective date: 20160804 |
|
PLAX | Notice of opposition and request to file observation + time limit sent |
Free format text: ORIGINAL CODE: EPIDOSNOBS2 |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: PLFP Year of fee payment: 5 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20151104 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: BE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20151104 |
|
PLBB | Reply of patent proprietor to notice(s) of opposition received |
Free format text: ORIGINAL CODE: EPIDOSNOBS3 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: MC Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20151104 |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: PL |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: MM4A |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: CH Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20160930 Ref country code: LI Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20160930 Ref country code: IE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20160926 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LU Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20160926 |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: PLFP Year of fee payment: 6 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R100 Ref document number: 602012012209 Country of ref document: DE |
|
PLCK | Communication despatched that opposition was rejected |
Free format text: ORIGINAL CODE: EPIDOSNREJ1 |
|
PLBN | Opposition rejected |
Free format text: ORIGINAL CODE: 0009273 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: OPPOSITION REJECTED |
|
27O | Opposition rejected |
Effective date: 20171120 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: HU Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT; INVALID AB INITIO Effective date: 20120926 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: CY Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20151104 Ref country code: MT Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20160930 Ref country code: MK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20151104 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: BG Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20151104 |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: PLFP Year of fee payment: 7 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: TR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20151104 Ref country code: AL Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20151104 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R081 Ref document number: 602012012209 Country of ref document: DE Owner name: UNILEVER GLOBAL IP LIMITED, WIRRAL, GB Free format text: FORMER OWNER: UNILEVER N.V., ROTTERDAM, NL |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: DE Payment date: 20210920 Year of fee payment: 10 |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: 732E Free format text: REGISTERED BETWEEN 20220127 AND 20220202 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R119 Ref document number: 602012012209 Country of ref document: DE |
|
P01 | Opt-out of the competence of the unified patent court (upc) registered |
Effective date: 20230425 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: DE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20230401 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: IT Payment date: 20230921 Year of fee payment: 12 Ref country code: GB Payment date: 20230920 Year of fee payment: 12 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: PL Payment date: 20230918 Year of fee payment: 12 Ref country code: FR Payment date: 20230928 Year of fee payment: 12 |