EP2756303A4 - Measurement of a fluorescent analyte using tissue excitation - Google Patents
Measurement of a fluorescent analyte using tissue excitationInfo
- Publication number
- EP2756303A4 EP2756303A4 EP12830997.8A EP12830997A EP2756303A4 EP 2756303 A4 EP2756303 A4 EP 2756303A4 EP 12830997 A EP12830997 A EP 12830997A EP 2756303 A4 EP2756303 A4 EP 2756303A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- measurement
- fluorescent analyte
- tissue excitation
- excitation
- tissue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012491 analyte Substances 0.000 title 1
- 230000005284 excitation Effects 0.000 title 1
- 238000005259 measurement Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
- A61B5/0088—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for oral or dental tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B26/00—Optical devices or arrangements for the control of light using movable or deformable optical elements
- G02B26/001—Optical devices or arrangements for the control of light using movable or deformable optical elements based on interference in an adjustable optical cavity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7271—Specific aspects of physiological measurement analysis
- A61B5/7275—Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/74—Details of notification to user or communication with user or patient ; user input means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
- A61K49/0036—Porphyrins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Optics & Photonics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Audiology, Speech & Language Pathology (AREA)
- Dentistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- General Physics & Mathematics (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161535064P | 2011-09-15 | 2011-09-15 | |
PCT/US2012/055492 WO2013040398A1 (en) | 2011-09-15 | 2012-09-14 | Measurement of a fluorescent analyte using tissue excitation |
Publications (3)
Publication Number | Publication Date |
---|---|
EP2756303A1 EP2756303A1 (en) | 2014-07-23 |
EP2756303A4 true EP2756303A4 (en) | 2015-04-15 |
EP2756303B1 EP2756303B1 (en) | 2018-08-22 |
Family
ID=47883782
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP12830997.8A Active EP2756303B1 (en) | 2011-09-15 | 2012-09-14 | Measurement of a fluorescent analyte using tissue excitation |
Country Status (10)
Country | Link |
---|---|
US (2) | US9999382B2 (en) |
EP (1) | EP2756303B1 (en) |
JP (1) | JP2014530668A (en) |
CN (1) | CN103930782A (en) |
CA (1) | CA2848737A1 (en) |
ES (1) | ES2689176T3 (en) |
IL (1) | IL231442A0 (en) |
MX (1) | MX362127B (en) |
WO (1) | WO2013040398A1 (en) |
ZA (1) | ZA201402730B (en) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3005933B8 (en) | 2013-05-30 | 2019-01-02 | HOYA Corporation | Method and device for generating image showing concentration distribution of biological substances in biological tissue |
WO2015054684A1 (en) * | 2013-10-11 | 2015-04-16 | The Trustees Of Columbia University In The City Of New York | System, method and computer-accessible medium for characterization of tissue |
JP6612050B2 (en) * | 2014-08-28 | 2019-11-27 | シスメックス株式会社 | Hematology analyzer, diagnosis support method, and computer program |
JP6204314B2 (en) | 2014-09-03 | 2017-09-27 | Hoya株式会社 | Electronic endoscope system |
CN106999118B (en) * | 2014-10-13 | 2020-07-17 | 葡萄糖传感器公司 | Analyte sensing device |
JP6356051B2 (en) * | 2014-11-21 | 2018-07-11 | Hoya株式会社 | Analytical apparatus and method of operating analytical apparatus |
CN107636446B (en) * | 2015-02-18 | 2021-11-23 | H·施特普 | Apparatus and method for tissue fluorescence measurement for blood fluorophore determination |
CN104833813B (en) * | 2015-05-12 | 2017-03-29 | 江苏英诺华医疗技术有限公司 | It is a kind of while the analyser with blood routine and biochemistry detection function |
US10048127B2 (en) * | 2015-08-05 | 2018-08-14 | Viavi Solutions Inc. | Optical filter and spectrometer |
KR101803250B1 (en) | 2016-01-20 | 2017-11-30 | (주)아이에스엠아이엔씨 | Technique and apparatus for spectrophotometry using broadband filters |
ITUB20160237A1 (en) * | 2016-01-26 | 2017-07-26 | Vision Engineering Italy Soc A Responsabilita Limitata | PROCEDURE FOR CONTROL OF THE DOSAGE OF A CHROMOPHOROR AGENT IN A CORNEAL FABRIC AND PROCEDURE FOR DOSING A CHROMOPHOROR AGENT IN A CORNEAL FABRIC |
CN110402385A (en) * | 2016-12-15 | 2019-11-01 | 美国杰莫洛吉克尔研究所有限公司 | Device and method for screening jewel |
DE102017101309A1 (en) | 2016-12-23 | 2018-06-28 | Georg Hennig | A method for quantitatively determining a fluorescent component in blood and a meter |
EP3639014A4 (en) * | 2017-06-14 | 2020-12-30 | Ubiqd Inc. | Fiber-coupled broadband light source |
CN107854116A (en) * | 2017-11-15 | 2018-03-30 | 上海交通大学 | A kind of oral soft tissue metabolism monitoring system and method |
WO2019213618A1 (en) * | 2018-05-03 | 2019-11-07 | Akoya Biosciences, Inc. | Multispectral sample imaging |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010132990A1 (en) * | 2009-05-22 | 2010-11-25 | British Columbia Cancer Agency Branch | Selective excitation light fluorescence imaging methods and apparatus |
WO2011063032A1 (en) * | 2009-11-17 | 2011-05-26 | Veralight, Inc. | Method and apparatus to detect coronary artery calcification or disease |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
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US5222495A (en) * | 1990-02-02 | 1993-06-29 | Angiomedics Ii, Inc. | Non-invasive blood analysis by near infrared absorption measurements using two closely spaced wavelengths |
US5279793A (en) * | 1992-09-01 | 1994-01-18 | Glass Alexander J | Optical osmometer for chemical detection |
US5341805A (en) * | 1993-04-06 | 1994-08-30 | Cedars-Sinai Medical Center | Glucose fluorescence monitor and method |
US5759767A (en) * | 1996-10-11 | 1998-06-02 | Joseph R. Lakowicz | Two-photon and multi-photon measurement of analytes in animal and human tissues and fluids |
US6485703B1 (en) * | 1998-07-31 | 2002-11-26 | The Texas A&M University System | Compositions and methods for analyte detection |
US6615061B1 (en) * | 1998-11-23 | 2003-09-02 | Abbott Laboratories | Optical sensor having a selectable sampling distance for determination of analytes |
JP4152532B2 (en) * | 1999-07-23 | 2008-09-17 | 倉敷紡績株式会社 | Optical measurement probe |
US6694158B2 (en) * | 2001-04-11 | 2004-02-17 | Motorola, Inc. | System using a portable detection device for detection of an analyte through body tissue |
AU2002337666A1 (en) | 2001-08-03 | 2003-02-17 | Joseph A. Izatt | Aspects of basic oct engine technologies for high speed optical coherence tomography and light source and other improvements in oct |
US8131332B2 (en) * | 2002-04-04 | 2012-03-06 | Veralight, Inc. | Determination of a measure of a glycation end-product or disease state using tissue fluorescence of various sites |
US20040259270A1 (en) * | 2003-06-19 | 2004-12-23 | Wolf David E. | System, device and method for exciting a sensor and detecting analyte |
US7251516B2 (en) * | 2004-05-11 | 2007-07-31 | Nostix Llc | Noninvasive glucose sensor |
US7377794B2 (en) * | 2005-03-01 | 2008-05-27 | Masimo Corporation | Multiple wavelength sensor interconnect |
US7733224B2 (en) * | 2006-06-30 | 2010-06-08 | Bao Tran | Mesh network personal emergency response appliance |
US7961316B2 (en) * | 2006-06-07 | 2011-06-14 | Optoplex Corporation | Optical spectrum analyzer with continuously rotating tunable filter |
US7603151B2 (en) * | 2006-08-22 | 2009-10-13 | Bayer Healthcare Llc | Non-invasive methods of using spectral information in determining analyte concentrations |
US8079955B2 (en) * | 2006-11-28 | 2011-12-20 | Isense Corporation | Method and apparatus for managing glucose control |
JP2008229024A (en) * | 2007-03-20 | 2008-10-02 | Olympus Corp | Fluorescence observation device |
US8306594B2 (en) * | 2008-06-12 | 2012-11-06 | Paseman Sabrina K | Transmission fluorometer |
EP2233913B1 (en) * | 2009-03-24 | 2017-07-19 | BAM Bundesanstalt für Materialforschung und -prüfung | Optical standard for calibrating and characterising optical measuring devices |
US9134243B2 (en) * | 2009-12-18 | 2015-09-15 | University Health Network | System and method for sub-surface fluorescence imaging |
CA2786740A1 (en) | 2010-01-22 | 2011-07-28 | British Columbia Cancer Agency Branch | Apparatus and methods for characterization of lung tissue by raman spectroscopy |
-
2012
- 2012-09-14 ES ES12830997.8T patent/ES2689176T3/en active Active
- 2012-09-14 EP EP12830997.8A patent/EP2756303B1/en active Active
- 2012-09-14 CN CN201280055860.4A patent/CN103930782A/en active Pending
- 2012-09-14 WO PCT/US2012/055492 patent/WO2013040398A1/en active Application Filing
- 2012-09-14 JP JP2014530868A patent/JP2014530668A/en active Pending
- 2012-09-14 CA CA2848737A patent/CA2848737A1/en not_active Abandoned
- 2012-09-14 MX MX2014003234A patent/MX362127B/en active IP Right Grant
-
2014
- 2014-03-10 IL IL231442A patent/IL231442A0/en unknown
- 2014-03-14 US US14/212,557 patent/US9999382B2/en active Active
- 2014-04-14 ZA ZA2014/02730A patent/ZA201402730B/en unknown
-
2018
- 2018-05-10 US US15/976,493 patent/US20190110718A1/en not_active Abandoned
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010132990A1 (en) * | 2009-05-22 | 2010-11-25 | British Columbia Cancer Agency Branch | Selective excitation light fluorescence imaging methods and apparatus |
WO2011063032A1 (en) * | 2009-11-17 | 2011-05-26 | Veralight, Inc. | Method and apparatus to detect coronary artery calcification or disease |
Non-Patent Citations (1)
Title |
---|
See also references of WO2013040398A1 * |
Also Published As
Publication number | Publication date |
---|---|
ES2689176T3 (en) | 2018-11-08 |
WO2013040398A1 (en) | 2013-03-21 |
US9999382B2 (en) | 2018-06-19 |
MX362127B (en) | 2019-01-07 |
CN103930782A (en) | 2014-07-16 |
EP2756303A1 (en) | 2014-07-23 |
EP2756303B1 (en) | 2018-08-22 |
US20190110718A1 (en) | 2019-04-18 |
US20140235973A1 (en) | 2014-08-21 |
ZA201402730B (en) | 2016-11-30 |
CA2848737A1 (en) | 2013-03-21 |
MX2014003234A (en) | 2014-12-05 |
IL231442A0 (en) | 2014-04-30 |
JP2014530668A (en) | 2014-11-20 |
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