EP2730577B8 - Crystal modification of 6-hydroxy-4-oxo-2,4-dihydro-1H-pyrrolo[3,2,1-ij]quinoline-5-carboxylic acid para-methoxyanilide - Google Patents

Crystal modification of 6-hydroxy-4-oxo-2,4-dihydro-1H-pyrrolo[3,2,1-ij]quinoline-5-carboxylic acid para-methoxyanilide Download PDF

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Publication number
EP2730577B8
EP2730577B8 EP13748963.9A EP13748963A EP2730577B8 EP 2730577 B8 EP2730577 B8 EP 2730577B8 EP 13748963 A EP13748963 A EP 13748963A EP 2730577 B8 EP2730577 B8 EP 2730577B8
Authority
EP
European Patent Office
Prior art keywords
methoxyanilide
pyrrolo
quinoline
dihydro
oxo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Not-in-force
Application number
EP13748963.9A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP2730577A4 (en
EP2730577B1 (en
EP2730577A1 (en
Inventor
Igor Vasilevich UKRAINETS
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otkrytoe Aktsionernoe Obschestvo Mezhdunarodnaya
Original Assignee
Otkrytoe Aktsionernoe Obschestvo Mezhdunarodnaya
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Filing date
Publication date
Application filed by Otkrytoe Aktsionernoe Obschestvo Mezhdunarodnaya filed Critical Otkrytoe Aktsionernoe Obschestvo Mezhdunarodnaya
Publication of EP2730577A1 publication Critical patent/EP2730577A1/en
Publication of EP2730577A4 publication Critical patent/EP2730577A4/en
Application granted granted Critical
Publication of EP2730577B1 publication Critical patent/EP2730577B1/en
Publication of EP2730577B8 publication Critical patent/EP2730577B8/en
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
EP13748963.9A 2012-02-16 2013-02-05 Crystal modification of 6-hydroxy-4-oxo-2,4-dihydro-1H-pyrrolo[3,2,1-ij]quinoline-5-carboxylic acid para-methoxyanilide Not-in-force EP2730577B8 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2012105420/04A RU2480468C1 (ru) 2012-02-16 2012-02-16 КРИСТАЛЛИЧЕСКАЯ МОДИФИКАЦИЯ ПАРА-МЕТОКСИАНИЛИДА 6-ГИДРОКСИ-4-ОКСО-2,4-ДИГИДРО-1Н-ПИРРОЛО[3,2,1-ij]ХИНОЛИН-5-КАРБОНОВОЙ КИСЛОТЫ
PCT/RU2013/000081 WO2013122509A1 (ru) 2012-02-16 2013-02-05 Кристаллическая модификация пара-метоксианилида 6-гидрокси-4-оксо-2,4-дигидро-1н-пирроло[3,2,1-ijхинолин-5-карбоновой кислоты

Publications (4)

Publication Number Publication Date
EP2730577A1 EP2730577A1 (en) 2014-05-14
EP2730577A4 EP2730577A4 (en) 2014-06-18
EP2730577B1 EP2730577B1 (en) 2015-04-08
EP2730577B8 true EP2730577B8 (en) 2015-09-02

Family

ID=48984510

Family Applications (1)

Application Number Title Priority Date Filing Date
EP13748963.9A Not-in-force EP2730577B8 (en) 2012-02-16 2013-02-05 Crystal modification of 6-hydroxy-4-oxo-2,4-dihydro-1H-pyrrolo[3,2,1-ij]quinoline-5-carboxylic acid para-methoxyanilide

Country Status (3)

Country Link
EP (1) EP2730577B8 (ru)
RU (1) RU2480468C1 (ru)
WO (1) WO2013122509A1 (ru)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0015601D0 (en) * 2000-06-26 2000-08-16 Ferring Bv Novel antidiuretic agents
UA86286C2 (ru) * 2007-07-19 2009-04-10 Национальный Фармацевтический Университет N-R-АМИДЫ 1-ГИДРОКСИ-3-ОКСО-5,6-ДИГИДРО-3Н-ПИРРОЛО-[3,2,1-ij]-ХИНОЛИН-2-КАРБОНОВОЙ КИСЛОТЫ, КОТОРЫЕ ПРОЯВЛЯЮТ ДИУРЕТИЧЕСКУЮ АКТИВНОСТЬ
UA86883C2 (ru) * 2007-10-23 2009-05-25 Ігор Васильович Українець Пара-метоксианилиды 4-гидрокси-2-оксо-1,2-дигидрохинолин-3-карбоновых кислот, которые проявляют диуретическую активность
UA86883U (ru) 2013-08-05 2014-01-10 Валентина Петрівна Труфанова Способ профилактики кариеса зубов у детей

Also Published As

Publication number Publication date
RU2480468C1 (ru) 2013-04-27
WO2013122509A1 (ru) 2013-08-22
EP2730577A4 (en) 2014-06-18
EP2730577B1 (en) 2015-04-08
EP2730577A1 (en) 2014-05-14

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