EP2709447A4 - Compositions, methods & systems for respiratory delivery of two or more active agents - Google Patents
Compositions, methods & systems for respiratory delivery of two or more active agentsInfo
- Publication number
- EP2709447A4 EP2709447A4 EP11865780.8A EP11865780A EP2709447A4 EP 2709447 A4 EP2709447 A4 EP 2709447A4 EP 11865780 A EP11865780 A EP 11865780A EP 2709447 A4 EP2709447 A4 EP 2709447A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- compositions
- systems
- methods
- active agents
- respiratory delivery
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L9/00—Disinfection, sterilisation or deodorisation of air
- A61L9/015—Disinfection, sterilisation or deodorisation of air using gaseous or vaporous substances, e.g. ozone
- A61L9/02—Disinfection, sterilisation or deodorisation of air using gaseous or vaporous substances, e.g. ozone using substances evaporated in the air by heating or combustion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Dispersion Chemistry (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Otolaryngology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2011/036868 WO2012158166A1 (en) | 2011-05-17 | 2011-05-17 | Compositions, methods & systems for respiratory delivery of two or more active agents |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2709447A1 EP2709447A1 (en) | 2014-03-26 |
EP2709447A4 true EP2709447A4 (en) | 2014-10-22 |
Family
ID=47177229
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP11865780.8A Withdrawn EP2709447A4 (en) | 2011-05-17 | 2011-05-17 | Compositions, methods & systems for respiratory delivery of two or more active agents |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP2709447A4 (en) |
JP (1) | JP2014518871A (en) |
KR (1) | KR20140032404A (en) |
CN (1) | CN103687483A (en) |
AU (1) | AU2011368334A1 (en) |
BR (1) | BR112013029507A2 (en) |
CA (1) | CA2835927A1 (en) |
EA (1) | EA201490991A1 (en) |
IL (1) | IL229260A0 (en) |
MX (1) | MX2013013440A (en) |
RU (1) | RU2013155903A (en) |
SG (1) | SG194896A1 (en) |
WO (1) | WO2012158166A1 (en) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8815258B2 (en) | 2009-05-29 | 2014-08-26 | Pearl Therapeutics, Inc. | Compositions, methods and systems for respiratory delivery of two or more active agents |
LT2435025T (en) | 2009-05-29 | 2016-09-26 | Pearl Therapeutics, Inc. | Respiratory delivery of active agents |
JP2016506947A (en) | 2013-01-31 | 2016-03-07 | プロソニックス リミテッド | Pharmaceutical composition comprising multicomponent crystal particles suitable for use in inhalation therapy |
KR102391332B1 (en) | 2013-03-15 | 2022-04-26 | 펄 테라퓨틱스 인코포레이티드 | Methods and systems for conditioning of particulate crystalline materials |
WO2014190204A1 (en) * | 2013-05-22 | 2014-11-27 | Pearl Therapeutics, Inc. | Compositions, methods & systems for respiratory delivery of three or more active agents |
MY176191A (en) * | 2013-12-30 | 2020-07-24 | Chiesi Farm Spa | Stable pressurised aerosol solution composition of glycopyrronium bromide and formoterol combination |
MX368835B (en) * | 2013-12-30 | 2019-10-18 | Chiesi Farm Spa | Stable pressurised aerosol solution composition of glycopyrronium bromide and formoterol combination. |
UA115958C2 (en) | 2014-09-09 | 2018-01-10 | Вектура Лімітед | Formulation comprising glycopyrrolate, method and apparatus |
US20160310410A1 (en) | 2015-04-24 | 2016-10-27 | Glenmark Specialty S.A. | Pharmaceutical compositions comprising arformoterol and glycopyrronium |
US20180147161A1 (en) * | 2015-05-01 | 2018-05-31 | Board Of Regents, The University Of Texas System | Multidrug brittle matrix compositions |
CN105125542A (en) * | 2015-08-23 | 2015-12-09 | 杭州紫金医药科技有限公司 | Medicine composition with tiotropium bromide and formoterol, application of medicine composition and preparation |
CN106880636A (en) * | 2015-12-15 | 2017-06-23 | 天津金耀集团有限公司 | A kind of ciclesonide folk prescription and compound dry powder inhalation composition |
CN106880637B (en) * | 2015-12-15 | 2021-01-29 | 天津金耀集团有限公司 | Ciclesonide formoterol and tiotropium bromide compound dry powder inhalant composition |
CN106943350A (en) * | 2017-03-14 | 2017-07-14 | 上海现代药物制剂工程研究中心有限公司 | Aerosol and preparation method containing muscarinic receptor antagonist and β 2 receptor agonist |
WO2020100040A1 (en) * | 2018-11-12 | 2020-05-22 | 3M Innovative Properties Company | Umeclidinium and vilanterol formulation and inhaler |
WO2021071967A1 (en) * | 2019-10-09 | 2021-04-15 | Island Breeze Systems Ca, Llc | Compositions for pulmonary delivery of cannabinoids and associated methods and systems |
CN111467498A (en) * | 2020-05-14 | 2020-07-31 | 王兆霖 | Pharmaceutical composition preparation |
CN116710104A (en) * | 2021-01-08 | 2023-09-05 | 江苏恒瑞医药股份有限公司 | Pharmaceutical compositions deliverable by metered dose inhaler |
WO2023283438A1 (en) * | 2021-07-09 | 2023-01-12 | Astrazeneca Pharmaceuticals Lp | Compositions, methods and systems for aerosol drug delivery |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050175549A1 (en) * | 2004-02-06 | 2005-08-11 | Sofotec Gmbh & Co. Kg | Novel combination of anticholinergic and ss mimetics for the treatment of respiratory diseases |
WO2010138862A2 (en) * | 2009-05-29 | 2010-12-02 | Pearl Therapeutics, Inc. | Compositions for respiratory delivery of active agents and associated methods and systems |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2304975C (en) * | 1997-09-29 | 2009-06-16 | Inhale Therapeutic Systems, Inc. | Stabilized preparations for use in metered dose inhalers |
US20060165606A1 (en) * | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
GB9903759D0 (en) * | 1999-02-18 | 1999-04-14 | Novartis Ag | Organic compounds |
SE527190C2 (en) * | 2003-06-19 | 2006-01-17 | Microdrug Ag | Administration of metered dry powder combined doses of finely divided dry medication powders involves selecting first and second medicaments for forming of pharmaceutical, combined doses |
US8815258B2 (en) * | 2009-05-29 | 2014-08-26 | Pearl Therapeutics, Inc. | Compositions, methods and systems for respiratory delivery of two or more active agents |
-
2011
- 2011-05-17 AU AU2011368334A patent/AU2011368334A1/en not_active Abandoned
- 2011-05-17 WO PCT/US2011/036868 patent/WO2012158166A1/en active Application Filing
- 2011-05-17 CN CN201180072341.4A patent/CN103687483A/en active Pending
- 2011-05-17 MX MX2013013440A patent/MX2013013440A/en unknown
- 2011-05-17 BR BR112013029507A patent/BR112013029507A2/en not_active IP Right Cessation
- 2011-05-17 EA EA201490991A patent/EA201490991A1/en unknown
- 2011-05-17 RU RU2013155903/15A patent/RU2013155903A/en not_active Application Discontinuation
- 2011-05-17 JP JP2014511329A patent/JP2014518871A/en active Pending
- 2011-05-17 KR KR1020137030446A patent/KR20140032404A/en not_active Application Discontinuation
- 2011-05-17 EP EP11865780.8A patent/EP2709447A4/en not_active Withdrawn
- 2011-05-17 SG SG2013083431A patent/SG194896A1/en unknown
- 2011-05-17 CA CA2835927A patent/CA2835927A1/en not_active Abandoned
-
2013
- 2013-11-05 IL IL229260A patent/IL229260A0/en unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050175549A1 (en) * | 2004-02-06 | 2005-08-11 | Sofotec Gmbh & Co. Kg | Novel combination of anticholinergic and ss mimetics for the treatment of respiratory diseases |
WO2010138862A2 (en) * | 2009-05-29 | 2010-12-02 | Pearl Therapeutics, Inc. | Compositions for respiratory delivery of active agents and associated methods and systems |
WO2010138884A2 (en) * | 2009-05-29 | 2010-12-02 | Pearl Therapeutics, Inc. | Compositions, methods & systems for respiratory delivery of two or more active agents |
Non-Patent Citations (1)
Title |
---|
See also references of WO2012158166A1 * |
Also Published As
Publication number | Publication date |
---|---|
SG194896A1 (en) | 2013-12-30 |
EA201490991A1 (en) | 2014-09-30 |
IL229260A0 (en) | 2014-01-30 |
MX2013013440A (en) | 2014-06-05 |
KR20140032404A (en) | 2014-03-14 |
JP2014518871A (en) | 2014-08-07 |
CA2835927A1 (en) | 2012-11-22 |
BR112013029507A2 (en) | 2019-09-24 |
RU2013155903A (en) | 2015-06-27 |
AU2011368334A1 (en) | 2013-11-21 |
CN103687483A (en) | 2014-03-26 |
EP2709447A1 (en) | 2014-03-26 |
WO2012158166A1 (en) | 2012-11-22 |
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Legal Events
Date | Code | Title | Description |
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PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
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17P | Request for examination filed |
Effective date: 20131213 |
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AK | Designated contracting states |
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AX | Request for extension of the european patent |
Extension state: BA ME |
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A4 | Supplementary search report drawn up and despatched |
Effective date: 20140924 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61P 11/08 20060101ALI20140918BHEP Ipc: A61K 9/72 20060101ALI20140918BHEP Ipc: A61K 31/167 20060101AFI20140918BHEP Ipc: A61P 11/00 20060101ALI20140918BHEP Ipc: A61K 31/40 20060101ALI20140918BHEP Ipc: A61K 9/10 20060101ALI20140918BHEP Ipc: A61K 9/12 20060101ALI20140918BHEP |
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