EP2680843A4 - Derivate von pyrazolsubstituierten amino-heteroaryl-verbindungen - Google Patents
Derivate von pyrazolsubstituierten amino-heteroaryl-verbindungenInfo
- Publication number
- EP2680843A4 EP2680843A4 EP20120751813 EP12751813A EP2680843A4 EP 2680843 A4 EP2680843 A4 EP 2680843A4 EP 20120751813 EP20120751813 EP 20120751813 EP 12751813 A EP12751813 A EP 12751813A EP 2680843 A4 EP2680843 A4 EP 2680843A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- pyrazole
- derivatives
- substituted amino
- heteroaryl compounds
- heteroaryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161448887P | 2011-03-03 | 2011-03-03 | |
PCT/US2012/027341 WO2012119006A2 (en) | 2011-03-03 | 2012-03-01 | Derivatives of pyrazole-substituted amino-heteroaryl compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2680843A2 EP2680843A2 (de) | 2014-01-08 |
EP2680843A4 true EP2680843A4 (de) | 2015-05-06 |
Family
ID=46758504
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP20120751813 Withdrawn EP2680843A4 (de) | 2011-03-03 | 2012-03-01 | Derivate von pyrazolsubstituierten amino-heteroaryl-verbindungen |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP2680843A4 (de) |
AU (1) | AU2012223281A1 (de) |
CA (1) | CA2829025A1 (de) |
MX (1) | MX2013010067A (de) |
WO (1) | WO2012119006A2 (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103304552B (zh) * | 2012-03-09 | 2016-12-28 | 广东东阳光药业有限公司 | 取代的吡啶化合物及其使用方法和用途 |
MX2015008187A (es) | 2012-12-20 | 2016-02-05 | Concert Pharmaceuticals Inc | Inhibidores de alk deuterados. |
CN104650049B (zh) * | 2013-08-28 | 2018-06-08 | 广东东阳光药业有限公司 | 取代的吡啶化合物及其使用方法和用途 |
WO2018213426A1 (en) | 2017-05-16 | 2018-11-22 | Vertex Pharmaceuticals Incorporated | Deuterated pyridone amides and prodrugs thereof as modulators of sodium channels |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006021884A2 (en) * | 2004-08-26 | 2006-03-02 | Pfizer Inc. | Enantiomerically pure aminoheteroaryl compounds as protein kinase inhibitors |
KR101026676B1 (ko) * | 2005-12-05 | 2011-04-04 | 화이자 프로덕츠 인코포레이티드 | 비정상 세포 성장의 치료 방법 |
EP2001870A2 (de) * | 2006-03-31 | 2008-12-17 | Schering Corporation | Kinase-inhibitoren |
CN101967140A (zh) * | 2010-09-14 | 2011-02-09 | 郑州泰基鸿诺药物科技有限公司 | 氘代克里唑蒂尼及其衍生物、制备方法和应用 |
-
2012
- 2012-03-01 AU AU2012223281A patent/AU2012223281A1/en not_active Abandoned
- 2012-03-01 EP EP20120751813 patent/EP2680843A4/de not_active Withdrawn
- 2012-03-01 WO PCT/US2012/027341 patent/WO2012119006A2/en active Application Filing
- 2012-03-01 CA CA2829025A patent/CA2829025A1/en not_active Abandoned
- 2012-03-01 MX MX2013010067A patent/MX2013010067A/es not_active Application Discontinuation
Non-Patent Citations (1)
Title |
---|
No further relevant documents disclosed * |
Also Published As
Publication number | Publication date |
---|---|
WO2012119006A3 (en) | 2014-04-17 |
EP2680843A2 (de) | 2014-01-08 |
AU2012223281A1 (en) | 2013-09-19 |
CA2829025A1 (en) | 2012-09-07 |
WO2012119006A2 (en) | 2012-09-07 |
MX2013010067A (es) | 2014-01-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20131002 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
AX | Request for extension of the european patent |
Extension state: BA ME |
|
R17D | Deferred search report published (corrected) |
Effective date: 20140417 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A01N 43/56 20060101AFI20141211BHEP Ipc: A61K 31/415 20060101ALI20141211BHEP |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20150407 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61P 35/00 20060101ALI20150330BHEP Ipc: A61K 31/517 20060101ALI20150330BHEP Ipc: A61K 31/4412 20060101ALI20150330BHEP Ipc: C07D 401/14 20060101ALI20150330BHEP Ipc: A01N 43/56 20060101AFI20150330BHEP Ipc: A61K 31/415 20060101ALI20150330BHEP Ipc: A61K 31/4545 20060101ALI20150330BHEP Ipc: A61K 45/06 20060101ALI20150330BHEP |
|
17Q | First examination report despatched |
Effective date: 20160418 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20160830 |