EP2643281A4 - Préparation de cyclohexanols substitués isomériquement purs - Google Patents

Préparation de cyclohexanols substitués isomériquement purs

Info

Publication number
EP2643281A4
EP2643281A4 EP11843794.6A EP11843794A EP2643281A4 EP 2643281 A4 EP2643281 A4 EP 2643281A4 EP 11843794 A EP11843794 A EP 11843794A EP 2643281 A4 EP2643281 A4 EP 2643281A4
Authority
EP
European Patent Office
Prior art keywords
preparation
isomerically pure
pure substituted
substituted cyclohexanols
cyclohexanols
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP11843794.6A
Other languages
German (de)
English (en)
Other versions
EP2643281A1 (fr
Inventor
Melanie Bonnekessel
Klaus Ditrich
Jürgen Däuwel
Achim Sorg
Wolfgang Ladner
Bryan Cooper
Rene Backes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Priority to EP11843794.6A priority Critical patent/EP2643281A4/fr
Publication of EP2643281A1 publication Critical patent/EP2643281A1/fr
Publication of EP2643281A4 publication Critical patent/EP2643281A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/14—Enzymes or microbial cells immobilised on or in an inorganic carrier
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/01—Carboxylic ester hydrolases (3.1.1)
    • C12Y301/01003—Triacylglycerol lipase (3.1.1.3)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
EP11843794.6A 2010-11-26 2011-11-21 Préparation de cyclohexanols substitués isomériquement purs Withdrawn EP2643281A4 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP11843794.6A EP2643281A4 (fr) 2010-11-26 2011-11-21 Préparation de cyclohexanols substitués isomériquement purs

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10192721 2010-11-26
EP11843794.6A EP2643281A4 (fr) 2010-11-26 2011-11-21 Préparation de cyclohexanols substitués isomériquement purs
PCT/IB2011/055199 WO2012069974A1 (fr) 2010-11-26 2011-11-21 Préparation de cyclohexanols substitués isomériquement purs

Publications (2)

Publication Number Publication Date
EP2643281A1 EP2643281A1 (fr) 2013-10-02
EP2643281A4 true EP2643281A4 (fr) 2014-06-04

Family

ID=46145433

Family Applications (1)

Application Number Title Priority Date Filing Date
EP11843794.6A Withdrawn EP2643281A4 (fr) 2010-11-26 2011-11-21 Préparation de cyclohexanols substitués isomériquement purs

Country Status (4)

Country Link
EP (1) EP2643281A4 (fr)
JP (1) JP2014500020A (fr)
CN (1) CN103221370B (fr)
WO (1) WO2012069974A1 (fr)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4665028A (en) * 1982-10-06 1987-05-12 Novo Industri A/S Method for production of an immobilized enzyme preparation by means of a crosslinking agent
DE10151292A1 (de) * 2001-10-22 2003-04-30 Basf Ag Lipase-Varianten
WO2005073215A1 (fr) * 2004-01-29 2005-08-11 Basf Aktiengesellschaft Procede pour preparer des alcools sous forme d'enantiomeres purs
US20100086983A1 (en) * 2008-09-29 2010-04-08 Akermin, Inc. Process for accelerated capture of carbon dioxide
EP2248906A1 (fr) * 2008-01-23 2010-11-10 Ajinomoto Co., Inc. Procédé de fabrication de l-aminoacide

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19931847A1 (de) * 1999-07-09 2001-01-11 Basf Ag Immobilisierte Lipase

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4665028A (en) * 1982-10-06 1987-05-12 Novo Industri A/S Method for production of an immobilized enzyme preparation by means of a crosslinking agent
DE10151292A1 (de) * 2001-10-22 2003-04-30 Basf Ag Lipase-Varianten
WO2005073215A1 (fr) * 2004-01-29 2005-08-11 Basf Aktiengesellschaft Procede pour preparer des alcools sous forme d'enantiomeres purs
EP2248906A1 (fr) * 2008-01-23 2010-11-10 Ajinomoto Co., Inc. Procédé de fabrication de l-aminoacide
US20100086983A1 (en) * 2008-09-29 2010-04-08 Akermin, Inc. Process for accelerated capture of carbon dioxide

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BREUER ET AL: "Industrial methods for the production of optically active intermediates", ANGEWANDTE CHEMIE, INTERNATIONAL EDITION, vol. 43, 2004, pages 788 - 824, XP002339848 *
COSTA-SILVA ET AL: "Partial purification and drying by spray dryer of extracellular lipases from the endophytic fungus Cercospora kikuchii", JOURNAL OF BIOTECHNOLOGY / SPECIAL ABSTRACTS, vol. 150S, pages S377, XP027489946 *
See also references of WO2012069974A1 *
STINSON: "Chiral Drugs", CHEMICAL & ENGINEERING NEWS, vol. 78, 2000, pages 1 - 10, XP002723173, Retrieved from the Internet <URL:http://www.technology-catalysts.com/pdf/TCI-CENews-1000.pdf> [retrieved on 20140409] *
XU ET AL: "Template-based modeling of a psychrophilic lipase: Conformational changes, novel structural features and its application in predicting the enantioselectivity of lipase catalyzed transesterification of secondary alcohols", BIOCHIMICA ET BIOPHYSICA ACTA, vol. 1804, 7 September 2010 (2010-09-07), pages 2183 - 2190, XP002723491 *
YAMAMOTO ET AL: "Drying of enzymes: Enzyme retention during drying of a single droplet", CHEMICAL ENGINEERING SCIENCE, vol. 47, 1992, pages 177 - 183, XP002723492 *

Also Published As

Publication number Publication date
WO2012069974A1 (fr) 2012-05-31
CN103221370B (zh) 2015-02-11
JP2014500020A (ja) 2014-01-09
EP2643281A1 (fr) 2013-10-02
CN103221370A (zh) 2013-07-24

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20140508

RIC1 Information provided on ipc code assigned before grant

Ipc: C12P 41/00 20060101AFI20140425BHEP

Ipc: C07C 35/08 20060101ALI20140425BHEP

Ipc: C12N 11/14 20060101ALI20140425BHEP

Ipc: C12P 7/02 20060101ALI20140425BHEP

17Q First examination report despatched

Effective date: 20141216

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Effective date: 20151121