EP2612707A1 - Vorrichtung und Verfahren zum Testen von biologischen Proben - Google Patents
Vorrichtung und Verfahren zum Testen von biologischen Proben Download PDFInfo
- Publication number
- EP2612707A1 EP2612707A1 EP12150239.7A EP12150239A EP2612707A1 EP 2612707 A1 EP2612707 A1 EP 2612707A1 EP 12150239 A EP12150239 A EP 12150239A EP 2612707 A1 EP2612707 A1 EP 2612707A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- reaction chamber
- housing
- insertion area
- reaction
- test cassette
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000012360 testing method Methods 0.000 title claims abstract description 181
- 239000012472 biological sample Substances 0.000 title claims abstract description 68
- 238000000034 method Methods 0.000 title claims abstract description 30
- 238000006243 chemical reaction Methods 0.000 claims abstract description 148
- 238000003780 insertion Methods 0.000 claims abstract description 77
- 230000037431 insertion Effects 0.000 claims abstract description 77
- 239000011541 reaction mixture Substances 0.000 claims abstract description 44
- 239000012491 analyte Substances 0.000 claims abstract description 36
- 239000012530 fluid Substances 0.000 claims abstract description 14
- 238000004891 communication Methods 0.000 claims abstract description 12
- 239000003153 chemical reaction reagent Substances 0.000 claims description 18
- 229940079593 drug Drugs 0.000 claims description 16
- 239000003814 drug Substances 0.000 claims description 16
- 238000003018 immunoassay Methods 0.000 claims description 13
- ZPUCINDJVBIVPJ-LJISPDSOSA-N cocaine Chemical compound O([C@H]1C[C@@H]2CC[C@@H](N2C)[C@H]1C(=O)OC)C(=O)C1=CC=CC=C1 ZPUCINDJVBIVPJ-LJISPDSOSA-N 0.000 claims description 6
- 210000004369 blood Anatomy 0.000 claims description 5
- 239000008280 blood Substances 0.000 claims description 5
- 210000002381 plasma Anatomy 0.000 claims description 5
- 210000003296 saliva Anatomy 0.000 claims description 5
- 210000002966 serum Anatomy 0.000 claims description 5
- 210000002700 urine Anatomy 0.000 claims description 5
- CYQFCXCEBYINGO-UHFFFAOYSA-N THC Natural products C1=C(C)CCC2C(C)(C)OC3=CC(CCCCC)=CC(O)=C3C21 CYQFCXCEBYINGO-UHFFFAOYSA-N 0.000 claims description 4
- CYQFCXCEBYINGO-IAGOWNOFSA-N delta1-THC Chemical compound C1=C(C)CC[C@H]2C(C)(C)OC3=CC(CCCCC)=CC(O)=C3[C@@H]21 CYQFCXCEBYINGO-IAGOWNOFSA-N 0.000 claims description 4
- 229960004242 dronabinol Drugs 0.000 claims description 4
- JTJMJGYZQZDUJJ-UHFFFAOYSA-N phencyclidine Chemical compound C1CCCCN1C1(C=2C=CC=CC=2)CCCCC1 JTJMJGYZQZDUJJ-UHFFFAOYSA-N 0.000 claims description 4
- USSIQXCVUWKGNF-UHFFFAOYSA-N 6-(dimethylamino)-4,4-diphenylheptan-3-one Chemical compound C=1C=CC=CC=1C(CC(C)N(C)C)(C(=O)CC)C1=CC=CC=C1 USSIQXCVUWKGNF-UHFFFAOYSA-N 0.000 claims description 3
- 238000005452 bending Methods 0.000 claims description 3
- 229940049706 benzodiazepine Drugs 0.000 claims description 3
- 150000001557 benzodiazepines Chemical class 0.000 claims description 3
- 229960003920 cocaine Drugs 0.000 claims description 3
- 229960001797 methadone Drugs 0.000 claims description 3
- 229950010883 phencyclidine Drugs 0.000 claims description 3
- 239000000427 antigen Substances 0.000 description 4
- 102000036639 antigens Human genes 0.000 description 4
- 108091007433 antigens Proteins 0.000 description 4
- 239000007853 buffer solution Substances 0.000 description 4
- 239000000523 sample Substances 0.000 description 4
- 238000000151 deposition Methods 0.000 description 3
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 2
- 238000011534 incubation Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000006177 biological buffer Substances 0.000 description 1
- 239000013060 biological fluid Substances 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000013270 controlled release Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 238000003317 immunochromatography Methods 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 238000002203 pretreatment Methods 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/52—Containers specially adapted for storing or dispensing a reagent
- B01L3/523—Containers specially adapted for storing or dispensing a reagent with means for closing or opening
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/04—Exchange or ejection of cartridges, containers or reservoirs
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/08—Ergonomic or safety aspects of handling devices
- B01L2200/087—Ergonomic aspects
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/16—Reagents, handling or storing thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/041—Connecting closures to device or container
- B01L2300/043—Hinged closures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0825—Test strips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0829—Multi-well plates; Microtitration plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0633—Valves, specific forms thereof with moving parts
- B01L2400/0638—Valves, specific forms thereof with moving parts membrane valves, flap valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5023—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
- B01L3/50853—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates with covers or lids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PT12150239T PT2612707E (pt) | 2012-01-05 | 2012-01-05 | Dispositivo e método para testar amostras biológicas |
ES12150239.7T ES2501843T3 (es) | 2012-01-05 | 2012-01-05 | Dispositivo y procedimiento de análisis de muestras biológicas |
EP20120150239 EP2612707B1 (de) | 2012-01-05 | 2012-01-05 | Vorrichtung und Verfahren zum Testen von biologischen Proben |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP20120150239 EP2612707B1 (de) | 2012-01-05 | 2012-01-05 | Vorrichtung und Verfahren zum Testen von biologischen Proben |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2612707A1 true EP2612707A1 (de) | 2013-07-10 |
EP2612707B1 EP2612707B1 (de) | 2014-06-11 |
Family
ID=45507430
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP20120150239 Active EP2612707B1 (de) | 2012-01-05 | 2012-01-05 | Vorrichtung und Verfahren zum Testen von biologischen Proben |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP2612707B1 (de) |
ES (1) | ES2501843T3 (de) |
PT (1) | PT2612707E (de) |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6406922B2 (en) | 1996-03-11 | 2002-06-18 | American Bio Medica Corp. | Device for the testing of body fluid samples |
WO2004038364A2 (en) * | 2002-10-22 | 2004-05-06 | Acon Laboratories, Inc. | In line test device and methods of use |
US7090803B1 (en) | 2003-10-28 | 2006-08-15 | American Bio Medica Corporation | Lateral flow immunoassay device |
WO2007026814A1 (ja) * | 2005-08-31 | 2007-03-08 | Fujirebio Inc. | 試験用具 |
US20090320623A1 (en) * | 2007-03-24 | 2009-12-31 | Michael Matallana-Kielmann | Device for a test strip holder, method and arrangement |
US7695953B2 (en) | 2007-01-09 | 2010-04-13 | American Bio Medica Corporation | Apparatus for high-sensitivity body fluid testing device |
EP2191896A1 (de) * | 2008-11-19 | 2010-06-02 | Kaltek S.r.l. | Vorrichtung zur Durchführung von schnellen Vorort-Tests biologischer Flüssigkeiten |
-
2012
- 2012-01-05 PT PT12150239T patent/PT2612707E/pt unknown
- 2012-01-05 ES ES12150239.7T patent/ES2501843T3/es active Active
- 2012-01-05 EP EP20120150239 patent/EP2612707B1/de active Active
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6406922B2 (en) | 1996-03-11 | 2002-06-18 | American Bio Medica Corp. | Device for the testing of body fluid samples |
WO2004038364A2 (en) * | 2002-10-22 | 2004-05-06 | Acon Laboratories, Inc. | In line test device and methods of use |
US7090803B1 (en) | 2003-10-28 | 2006-08-15 | American Bio Medica Corporation | Lateral flow immunoassay device |
WO2007026814A1 (ja) * | 2005-08-31 | 2007-03-08 | Fujirebio Inc. | 試験用具 |
US7695953B2 (en) | 2007-01-09 | 2010-04-13 | American Bio Medica Corporation | Apparatus for high-sensitivity body fluid testing device |
US20090320623A1 (en) * | 2007-03-24 | 2009-12-31 | Michael Matallana-Kielmann | Device for a test strip holder, method and arrangement |
EP2191896A1 (de) * | 2008-11-19 | 2010-06-02 | Kaltek S.r.l. | Vorrichtung zur Durchführung von schnellen Vorort-Tests biologischer Flüssigkeiten |
Also Published As
Publication number | Publication date |
---|---|
PT2612707E (pt) | 2014-09-17 |
EP2612707B1 (de) | 2014-06-11 |
ES2501843T3 (es) | 2014-10-02 |
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