EP2606121A4 - Compositions comrpising perivascular stem cells and nell-1 protein - Google Patents
Compositions comrpising perivascular stem cells and nell-1 proteinInfo
- Publication number
- EP2606121A4 EP2606121A4 EP11818825.9A EP11818825A EP2606121A4 EP 2606121 A4 EP2606121 A4 EP 2606121A4 EP 11818825 A EP11818825 A EP 11818825A EP 2606121 A4 EP2606121 A4 EP 2606121A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- comrpising
- nell
- protein
- compositions
- stem cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
- A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0654—Osteocytes, Osteoblasts, Odontocytes; Bones, Teeth
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0668—Mesenchymal stem cells from other natural sources
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/64—Animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/998—Proteins not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/03—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from non-embryonic pluripotent stem cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Cell Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Virology (AREA)
- Surgery (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Reproductive Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Marine Sciences & Fisheries (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Gynecology & Obstetrics (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US40190510P | 2010-08-19 | 2010-08-19 | |
PCT/US2011/048393 WO2012024573A2 (en) | 2010-08-19 | 2011-08-19 | Compositions comrpising perivascular stem cells and nell-1 protein |
Publications (3)
Publication Number | Publication Date |
---|---|
EP2606121A2 EP2606121A2 (en) | 2013-06-26 |
EP2606121A4 true EP2606121A4 (en) | 2014-01-15 |
EP2606121B1 EP2606121B1 (en) | 2016-05-11 |
Family
ID=45605685
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP11818825.9A Not-in-force EP2606121B1 (en) | 2010-08-19 | 2011-08-19 | Compositions comrpising perivascular stem cells and nell-1 protein |
Country Status (5)
Country | Link |
---|---|
US (2) | US9301976B2 (en) |
EP (1) | EP2606121B1 (en) |
CN (1) | CN103080301B (en) |
AU (1) | AU2011291537B2 (en) |
WO (1) | WO2012024573A2 (en) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2411406B1 (en) | 2009-03-25 | 2017-03-01 | The Regents of The University of California | Isoform nell-1 peptide |
AU2011291537B2 (en) | 2010-08-19 | 2016-06-02 | The Regents Of The University Of California | Compositions comprising perivascular stem cells and Nell-1 protein |
US9044430B2 (en) | 2011-03-18 | 2015-06-02 | Microvascular Tissues, Inc. | Allogeneic microvascular tissue for soft tissue treatments |
EP2734618B1 (en) * | 2011-07-20 | 2017-06-14 | Paracelsus Medizinische Privatuniversität Salzburg - Privatstiftung | Pluripotent tendon and ligament perivascular cells |
ES2899209T3 (en) | 2012-09-19 | 2022-03-10 | Microvascular Tissues Inc | Compositions and methods for treating and preventing tissue injury and disease |
US11819522B2 (en) | 2012-09-19 | 2023-11-21 | Microvascular Tissues, Inc. | Compositions and methods for treating and preventing tissue injury and disease |
US10596202B2 (en) | 2012-09-19 | 2020-03-24 | Microvascular Tissues, Inc. | Compositions and methods for treating and preventing tissue injury and disease |
US9872937B2 (en) | 2012-09-19 | 2018-01-23 | Microvascular Tissues, Inc. | Compositions and methods for treating and preventing tissue injury and disease |
WO2015153586A1 (en) * | 2014-03-31 | 2015-10-08 | The Johns Hopkins University | Pluripotent stem cell therapies for ischemic retinopathies |
PT3370698T (en) | 2015-11-03 | 2022-03-02 | Zoetis Services Llc | Sol-gel polymer composites and uses thereof |
WO2017151950A1 (en) * | 2016-03-02 | 2017-09-08 | Microvascular Tissues, Inc | Enhanced multipotent cells and microvascular tissue and methods of use thereof |
KR101991624B1 (en) * | 2018-04-11 | 2019-06-20 | 서울대학교산학협력단 | Transformant derived from diabetes individual, manufacturing method the smae, and cellular therapeutic agents comprising the same |
WO2020092734A1 (en) * | 2018-10-31 | 2020-05-07 | The Regents Of The University Of California | Composition and method for arthritis |
CN110172443B (en) * | 2019-05-23 | 2022-07-29 | 中国人民解放军第四军医大学 | Method for constructing tissue engineering cartilage by using bone marrow mesenchymal stem cells |
CN113403272B (en) * | 2021-07-23 | 2022-09-20 | 廊坊康宝汇泰生物技术有限公司 | Culture medium of primary umbilical cord mesenchymal stem cells and application thereof |
CN115094024B (en) * | 2022-07-12 | 2024-01-26 | 首都医科大学附属北京安贞医院 | Method for purifying and identifying dermal microvascular pericytes and purified cells |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006089023A2 (en) * | 2005-02-16 | 2006-08-24 | The Regents Of The University Of California | Pharmaceutical compositions for treating or preventing bone conditions |
WO2008020815A1 (en) * | 2006-08-15 | 2008-02-21 | Agency For Science, Technology And Research | Mesenchymal stem cell conditioned medium |
WO2008148105A1 (en) * | 2007-05-25 | 2008-12-04 | Medistem Laboratories, Inc. | Endometrial stem cells and methods of making and using same |
WO2008155659A2 (en) * | 2007-04-24 | 2008-12-24 | Yaojiong Wu | Compositions for preventing or treating skin defects and methods of use thereof |
WO2010042654A2 (en) * | 2008-10-07 | 2010-04-15 | The Regents Of The University Of California | Recombinant nell protein production |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
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US4563489A (en) | 1984-02-10 | 1986-01-07 | University Of California | Biodegradable organic polymer delivery system for bone morphogenetic protein |
US5074916A (en) | 1990-05-18 | 1991-12-24 | Geltech, Inc. | Alkali-free bioactive sol-gel compositions |
US5124151A (en) | 1990-08-07 | 1992-06-23 | Mediventures Inc. | Drug delivery by injection with thermo-irreversible gels |
US5410016A (en) | 1990-10-15 | 1995-04-25 | Board Of Regents, The University Of Texas System | Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers |
CA2169191C (en) | 1993-08-26 | 2008-01-15 | Elizabeth A. Wang | Neural regeneration using human bone morphogenetic proteins |
US5385887A (en) | 1993-09-10 | 1995-01-31 | Genetics Institute, Inc. | Formulations for delivery of osteogenic proteins |
AU1734895A (en) | 1994-03-08 | 1995-09-25 | Genetics Institute Inc. | Methods and compositions for treatment of periodontal disease and repair of periodontal lesions |
US5817470A (en) | 1995-03-10 | 1998-10-06 | Sociedad Biotecnologica Collico Limitada | Immobilization of antigens to solid support by the mussel adhesive polyphenolic protein and the method for use therein |
ES2225870T3 (en) | 1996-02-29 | 2005-03-16 | Bioactive Bone Substitute Oy, Ab | OSTEOGENIC DEVICE AND ITS PREPARATION PROCEDURE. |
US6013591A (en) | 1997-01-16 | 2000-01-11 | Massachusetts Institute Of Technology | Nanocrystalline apatites and composites, prostheses incorporating them, and method for their production |
CA2371914A1 (en) | 1999-05-20 | 2000-11-30 | Russell A. Giordano | Polymer re-inforced anatomically accurate bioactive prostheses |
AU2003901668A0 (en) * | 2003-03-28 | 2003-05-01 | Medvet Science Pty. Ltd. | Non-haemopoietic precursor cells |
US7052856B2 (en) | 1999-10-05 | 2006-05-30 | The Regents Of The University Of California | NELL-1 enhanced bone mineralization |
WO2001070288A2 (en) | 2000-03-23 | 2001-09-27 | Genetics Institute, Inc. | Thermoreversible polymers for delivery and retention of osteoinductive proteins |
US6426114B1 (en) | 2000-05-02 | 2002-07-30 | The University Of British Columbia | Sol-gel calcium phosphate ceramic coatings and method of making same |
EP1406678B1 (en) | 2001-04-25 | 2009-01-14 | Eidgenössische Technische Hochschule Zürich | Drug delivery matrices to enhance wound healing |
TWI267378B (en) | 2001-06-08 | 2006-12-01 | Wyeth Corp | Calcium phosphate delivery vehicles for osteoinductive proteins |
US20030087338A1 (en) | 2001-07-20 | 2003-05-08 | Messersmith Phillip B. | Adhesive DOPA-containing polymers and related methods of use |
EP1446445A4 (en) | 2001-09-21 | 2007-04-04 | Stryker Corp | Pore-forming agents for orthopedic cements |
AU2003237748A1 (en) | 2002-07-02 | 2004-01-23 | Biopolymer Products Of Sweden Ab | Use of an acidic aqueous solution of a bioadhesive polyphenolic protein as an adhesive or coating |
EP1416307A1 (en) * | 2002-10-31 | 2004-05-06 | Alcatel | Bidirectional telescope |
CA2642381A1 (en) * | 2006-02-16 | 2007-08-23 | Fondazione Centro San Raffaele Del Monte Tabor | Skeletal muscle periangioblasts and cardiac mesoangioblasts, method for isolation and uses thereof |
US20070264239A1 (en) * | 2006-05-10 | 2007-11-15 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Isolation of pericytes |
WO2009045800A1 (en) * | 2007-09-28 | 2009-04-09 | Culiat Cymbeline T | Treatment of cardiovascular disorders using the cell differentiation signaling protein nell1 |
US9399758B2 (en) * | 2009-07-15 | 2016-07-26 | Mari Dezawa | SSEA3(+) pluripotent stem cell that can be isolated from body tissue |
WO2011021194A2 (en) * | 2009-08-17 | 2011-02-24 | Technion Research & Development Foundation Ltd. | Pericyte progenitor cells and methods of generating and using same |
WO2011022070A2 (en) | 2009-08-20 | 2011-02-24 | The Regents Of The University Of California | Perivascular stem cell composition for bone |
EP2516620B1 (en) * | 2009-12-23 | 2016-09-14 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Apparatus and method for cell exploitation |
AU2011291537B2 (en) | 2010-08-19 | 2016-06-02 | The Regents Of The University Of California | Compositions comprising perivascular stem cells and Nell-1 protein |
-
2011
- 2011-08-19 AU AU2011291537A patent/AU2011291537B2/en not_active Ceased
- 2011-08-19 US US13/816,488 patent/US9301976B2/en not_active Expired - Fee Related
- 2011-08-19 WO PCT/US2011/048393 patent/WO2012024573A2/en active Application Filing
- 2011-08-19 EP EP11818825.9A patent/EP2606121B1/en not_active Not-in-force
- 2011-08-19 CN CN201180040200.4A patent/CN103080301B/en not_active Expired - Fee Related
-
2016
- 2016-04-04 US US15/090,443 patent/US10675307B2/en not_active Expired - Fee Related
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006089023A2 (en) * | 2005-02-16 | 2006-08-24 | The Regents Of The University Of California | Pharmaceutical compositions for treating or preventing bone conditions |
WO2008020815A1 (en) * | 2006-08-15 | 2008-02-21 | Agency For Science, Technology And Research | Mesenchymal stem cell conditioned medium |
WO2008155659A2 (en) * | 2007-04-24 | 2008-12-24 | Yaojiong Wu | Compositions for preventing or treating skin defects and methods of use thereof |
WO2008148105A1 (en) * | 2007-05-25 | 2008-12-04 | Medistem Laboratories, Inc. | Endometrial stem cells and methods of making and using same |
WO2010042654A2 (en) * | 2008-10-07 | 2010-04-15 | The Regents Of The University Of California | Recombinant nell protein production |
Non-Patent Citations (6)
Title |
---|
CHEN C W ET AL: "Perivascular multi-lineage progenitor cells in human organs: Regenerative units, cytokine sources or both?", CYTOKINE AND GROWTH FACTOR REVIEWS, ELSEVIER LTD, GB, vol. 20, no. 5-6, 1 October 2009 (2009-10-01), pages 429 - 434, XP026790612, ISSN: 1359-6101, [retrieved on 20091129] * |
CRISAN M ET AL: "A Perivascular Origin for Mesenchymal Stem Cells in Multiple Human Organs", CELL STEM CELL, ELSEVIER, CELL PRESS, AMSTERDAM, NL, vol. 3, no. 3, 11 September 2008 (2008-09-11), pages 301 - 313, XP002611378, ISSN: 1934-5909, [retrieved on 20080910], DOI: 10.1016/J.STEM.2008.07.003 * |
HE W ET AL: "Pericyte-based human tissue engineered vascular grafts", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, vol. 31, no. 32, 3 August 2010 (2010-08-03), pages 8235 - 8244, XP027259528, ISSN: 0142-9612, [retrieved on 20100803] * |
LUDOVIC ZIMMERLIN ET AL: "Stromal vascular progenitors in adult human adipose tissue", CYTOMETRY PART A, vol. 9999A, 1 January 2009 (2009-01-01), pages NA - NA, XP055091951, ISSN: 1552-4922, DOI: 10.1002/cyto.a.20813 * |
MIHAELA CRISAN ET AL: "Perivascular Multipotent Progenitor Cells in Human Organs", ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, vol. 1176, no. 1, 25 September 2009 (2009-09-25), pages 118 - 123, XP055091952, ISSN: 0077-8923, DOI: 10.1111/j.1749-6632.2009.04967.x * |
See also references of WO2012024573A2 * |
Also Published As
Publication number | Publication date |
---|---|
US20160271186A1 (en) | 2016-09-22 |
WO2012024573A2 (en) | 2012-02-23 |
CN103080301A (en) | 2013-05-01 |
EP2606121B1 (en) | 2016-05-11 |
US20130309207A1 (en) | 2013-11-21 |
AU2011291537A1 (en) | 2013-03-21 |
CN103080301B (en) | 2016-10-19 |
US10675307B2 (en) | 2020-06-09 |
US9301976B2 (en) | 2016-04-05 |
WO2012024573A3 (en) | 2012-04-26 |
AU2011291537B2 (en) | 2016-06-02 |
EP2606121A2 (en) | 2013-06-26 |
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