EP2593133A4 - Protéine de surface de staphylococcus aureus sa1789 et vaccin protecteur basé sur ladite protéine - Google Patents

Protéine de surface de staphylococcus aureus sa1789 et vaccin protecteur basé sur ladite protéine

Info

Publication number
EP2593133A4
EP2593133A4 EP11816747.7A EP11816747A EP2593133A4 EP 2593133 A4 EP2593133 A4 EP 2593133A4 EP 11816747 A EP11816747 A EP 11816747A EP 2593133 A4 EP2593133 A4 EP 2593133A4
Authority
EP
European Patent Office
Prior art keywords
staphylococcus aureus
surface protein
vaccine based
protective vaccine
aureus surface
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP11816747.7A
Other languages
German (de)
English (en)
Other versions
EP2593133A1 (fr
Inventor
Tessie B Mcneely
Hongxia Fan
Mark Andrew Miller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Merck Sharp and Dohme LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp and Dohme LLC filed Critical Merck Sharp and Dohme LLC
Publication of EP2593133A1 publication Critical patent/EP2593133A1/fr
Publication of EP2593133A4 publication Critical patent/EP2593133A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/085—Staphylococcus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
EP11816747.7A 2010-07-13 2011-07-08 Protéine de surface de staphylococcus aureus sa1789 et vaccin protecteur basé sur ladite protéine Withdrawn EP2593133A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36389310P 2010-07-13 2010-07-13
US36636010P 2010-07-21 2010-07-21
PCT/US2011/043274 WO2012021229A1 (fr) 2010-07-13 2011-07-08 Protéine de surface de staphylococcus aureus sa1789 et vaccin protecteurbasé sur ladite protéine

Publications (2)

Publication Number Publication Date
EP2593133A1 EP2593133A1 (fr) 2013-05-22
EP2593133A4 true EP2593133A4 (fr) 2014-11-26

Family

ID=45567897

Family Applications (1)

Application Number Title Priority Date Filing Date
EP11816747.7A Withdrawn EP2593133A4 (fr) 2010-07-13 2011-07-08 Protéine de surface de staphylococcus aureus sa1789 et vaccin protecteur basé sur ladite protéine

Country Status (3)

Country Link
US (1) US8747858B2 (fr)
EP (1) EP2593133A4 (fr)
WO (1) WO2012021229A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012065034A1 (fr) 2010-11-12 2012-05-18 Merck Sharp & Dohme Corp. Vaccins à base de conjugués de peptide énolase, contre staphylococcus aureus
EP2773370A4 (fr) 2011-10-31 2016-09-28 Merck Sharp & Dohme Vaccin prophylactique à base de la protéine sa2451 de staphylococcus aureus
US9376487B2 (en) 2012-07-10 2016-06-28 Merck Sharp & Dohme Corp. Protective vaccine based on Staphylococcus aureus SA2493 protein

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002094868A2 (fr) * 2001-03-27 2002-11-28 Chiron Srl. Proteines et acides nucleiques de staphylococcus aureus
WO2008066931A2 (fr) * 2006-11-29 2008-06-05 Novozymes, Inc. Chromosome de bacillus licheniformis

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5091513A (en) 1987-05-21 1992-02-25 Creative Biomolecules, Inc. Biosynthetic antibody binding sites
US5785973A (en) 1988-02-01 1998-07-28 Praxis Biologics, Inc. Synthetic peptides representing a T-cell epitope as a carrier molecule for conjugate vaccines
CZ289308B6 (cs) 1993-12-23 2001-12-12 Merck & Co., Inc. Homologní rekombinantní expresní vektor pro expresi rekombinantních genů a způsob exprese rekombinantních genů
US6593114B1 (en) 1996-01-05 2003-07-15 Human Genome Sciences, Inc. Staphylococcus aureus polynucleotides and sequences
US6737248B2 (en) 1996-01-05 2004-05-18 Human Genome Sciences, Inc. Staphylococcus aureus polynucleotides and sequences
GB0014907D0 (en) 2000-06-20 2000-08-09 Univ Sheffield Antigenic polypeptides
AT410798B (de) 2001-01-26 2003-07-25 Cistem Biotechnologies Gmbh Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen
US20060188515A1 (en) 2003-07-24 2006-08-24 Anderson Annaliesa S Polypeptides for inducing a protective immune response against staphylococcus aureus
KR20060065643A (ko) 2003-07-24 2006-06-14 머크 앤드 캄파니 인코포레이티드 스타필로코쿠스 아우레우스에 대한 방어 면역 반응을유도하는 폴리펩타이드
CA2555342A1 (fr) 2004-02-18 2005-09-01 Merck & Co., Inc. Polypeptides d'induction d'une reponse immune protectrice contre staphylococcus aureus
EP1725255A4 (fr) 2004-02-27 2007-07-11 Merck & Co Inc Polypeptides destines a induire une reponse immunitaire de protection contre le staphylococcus aureus
US20070243205A1 (en) 2004-05-25 2007-10-18 Anderson Annaliesa S Polypeptides for Inducing a Protective Immune Response Against Staphylococcus Aureus
AU2005287145A1 (en) 2004-09-17 2006-03-30 Merck & Co., Inc. Polypeptides for inducing a protective immune response against Staphylococcus aureus
AU2006206577B2 (en) 2005-01-21 2012-03-08 Merck Sharp & Dohme Corp. Polypeptides for inducing a protective immune response against Staphylococcus aureus
US20090317421A1 (en) * 2006-01-18 2009-12-24 Dominique Missiakas Compositions and methods related to staphylococcal bacterium proteins
EP2376111A4 (fr) 2008-11-26 2013-01-09 Merck Sharp & Dohme Polypeptides pour induire une réponse immunitaire protectrice contre staphylococcus aureus
EP2384201A4 (fr) 2008-11-26 2013-01-09 Merck Sharp & Dohme Polypeptides pour induire une réponse immunitaire de protection contre le staphylocoque doré

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002094868A2 (fr) * 2001-03-27 2002-11-28 Chiron Srl. Proteines et acides nucleiques de staphylococcus aureus
WO2008066931A2 (fr) * 2006-11-29 2008-06-05 Novozymes, Inc. Chromosome de bacillus licheniformis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2012021229A1 *

Also Published As

Publication number Publication date
WO2012021229A1 (fr) 2012-02-16
US20130122034A1 (en) 2013-05-16
EP2593133A1 (fr) 2013-05-22
US8747858B2 (en) 2014-06-10

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20130213

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20141029

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 39/00 20060101AFI20141023BHEP

Ipc: C07K 14/195 20060101ALI20141023BHEP

Ipc: A61K 39/085 20060101ALI20141023BHEP

Ipc: A61K 39/38 20060101ALI20141023BHEP

17Q First examination report despatched

Effective date: 20161014

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20181026