EP2560977A4 - Neue ag(i)-verbindungen mit chelatbildenden liganden und ihre verwendung in pharmazeutischen zusammensetzungen - Google Patents

Neue ag(i)-verbindungen mit chelatbildenden liganden und ihre verwendung in pharmazeutischen zusammensetzungen

Info

Publication number
EP2560977A4
EP2560977A4 EP11772330.4A EP11772330A EP2560977A4 EP 2560977 A4 EP2560977 A4 EP 2560977A4 EP 11772330 A EP11772330 A EP 11772330A EP 2560977 A4 EP2560977 A4 EP 2560977A4
Authority
EP
European Patent Office
Prior art keywords
compounds
new
pharmaceutical compositions
chelating ligands
chelating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP11772330.4A
Other languages
English (en)
French (fr)
Other versions
EP2560977A1 (de
Inventor
Vratislav Langer
Morsy Abu-Youssef
Gohar Yousry
A Massoud Alshima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP2560977A1 publication Critical patent/EP2560977A1/de
Publication of EP2560977A4 publication Critical patent/EP2560977A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/005—Compounds containing elements of Groups 1 or 11 of the Periodic Table without C-Metal linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/38—Silver; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
EP11772330.4A 2010-04-22 2011-04-21 Neue ag(i)-verbindungen mit chelatbildenden liganden und ihre verwendung in pharmazeutischen zusammensetzungen Withdrawn EP2560977A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE1000411 2010-04-22
PCT/SE2011/050492 WO2011133104A1 (en) 2010-04-22 2011-04-21 New ag(i) compounds with chelating ligands and their use in pharmaceutical compositions

Publications (2)

Publication Number Publication Date
EP2560977A1 EP2560977A1 (de) 2013-02-27
EP2560977A4 true EP2560977A4 (de) 2013-11-27

Family

ID=44834386

Family Applications (1)

Application Number Title Priority Date Filing Date
EP11772330.4A Withdrawn EP2560977A4 (de) 2010-04-22 2011-04-21 Neue ag(i)-verbindungen mit chelatbildenden liganden und ihre verwendung in pharmazeutischen zusammensetzungen

Country Status (2)

Country Link
EP (1) EP2560977A4 (de)
WO (1) WO2011133104A1 (de)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004270730B2 (en) * 2003-09-05 2012-02-02 The University Of Akron Metal complexes of N-heterocyclic carbenes as radiopharmaceuticals and antibiotics
US20100234339A1 (en) * 2007-05-31 2010-09-16 Cse Incubation Ab Silver(i) compounds and their use in pharmaceutical compositions for the treatment,prophylaxis and prevention of infections

Non-Patent Citations (13)

* Cited by examiner, † Cited by third party
Title
A OYA ET AL: "Preparation of an antibacterial ceramic filter from montmorillonite supporting silver chelate of 2,2'-dipyridyl", APPLIED CLAY SCIENCE, vol. 8, no. 5, 1 January 1994 (1994-01-01), pages 365 - 371, XP055082703, ISSN: 0169-1317, DOI: 10.1016/0169-1317(94)90025-6 *
ANNA BELLUSCI ET AL: "Anion dependent mesomorphism in coordination networks based on 2,2'-bipyridine silver(i) complexes", DALTON TRANSACTIONS, no. 36, 1 January 2009 (2009-01-01), pages 7381, XP055082691, ISSN: 1477-9226, DOI: 10.1039/b906178a *
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; ESHWIKA, AHMED ET AL: "Metal complexes of 1,10-phenanthroline-5,6-dione alter the susceptibility of the yeast Candida albicans to amphotericin B and miconazole", XP002714384, retrieved from STN Database accession no. 2004:438748 *
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; ONUEGBU, JONATHAN ET AL: "Acetato(1,10-phenanthroline-5,6-dione)silver(I) trihydrate", XP002714383, retrieved from STN Database accession no. 2008:148784 *
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; WANG, YOUXIANG ET AL: "Syntheses and Electrochemical, Photophysical, and Photochemical Properties of Ruthenium(II) 4,5-Diazafluorenone Complexes and Their Ketal Derivatives", XP002714382, retrieved from STN Database accession no. 1998:229743 *
ESHWIKA, AHMED ET AL: "Metal complexes of 1,10-phenanthroline-5,6-dione alter the susceptibility of the yeast Candida albicans to amphotericin B and miconazole", BIOMETALS , 17(4), 415-422 CODEN: BOMEEH; ISSN: 0966-0844, 2004 *
F YILMAZ: "5,5-Diethylbarbiturate Complexes of Silver with 2,2'-Bipyridine and 3-(2-Pyridyl)propanol: Syntheses, Crystal Structures, Spectroscopic, Thermal and Antimicrobial Activity Studies", ZEITSCHRIFT FUER NATURFORSCHUNG, TEIL B: CHEMICAL SCIENCES, vol. 63b, 1 January 2008 (2008-01-01), pages 134 - 138, XP055082684 *
FUMIHIKO OHASHI ET AL: "Antimicrobial and antifungal agents derived from clay minerals (II): properties of montmorillonite supported by silver chelates of 1,10-phenanthroline and 2,2'-dipyridyl", APPLIED CLAY SCIENCE, vol. 6, no. 4, 1 January 1992 (1992-01-01), pages 301 - 310, XP055082704, ISSN: 0169-1317, DOI: 10.1016/S0169-1317(09)90005-9 *
MORSY A. M. ABU-YOUSSEF ET AL: "Synthesis, Crystal Structure, Quantum Chemical Calculations, DNA Interactions, and Antimicrobial Activity of [Ag(2-amino-3-methylpyridine) 2 ]NO 3 and [Ag(pyridine-2-carboxaldoxime)NO 3 ]", INORGANIC CHEMISTRY, vol. 49, no. 21, 1 November 2010 (2010-11-01), pages 9788 - 9797, XP055082683, ISSN: 0020-1669, DOI: 10.1021/ic100581k *
ONUEGBU, JONATHAN ET AL: "Acetato(1,10-phenanthroline-5,6-dione)silver(I) trihydrate", ACTA CRYSTALLOGRAPHICA, SECTION E: STRUCTURE REPORTS ONLINE , 64(2), M403-M404, M403/1-M403/9 CODEN: ACSEBH; ISSN: 1600-5368 URL: HTTP://JOURNALS.IUCR.ORG/E/ISSUES/2008/02/00/CI2544/CI2544.PDF, 2008 *
RODNEY P. FEAZELL ET AL: "Variability in the Structures of Luminescent [2-(Aminomethyl)pyridine]silver(I) Complexes: Effect of Ligand Ratio, Anion, Hydrogen Bonding, and [pi]-Stacking", EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, vol. 2005, no. 16, 1 August 2005 (2005-08-01), pages 3287 - 3297, XP055082688, ISSN: 1434-1948, DOI: 10.1002/ejic.200500215 *
See also references of WO2011133104A1 *
YOUXIANG WANG ET AL: "Syntheses and Electrochemical, Photophysical, and Photochemical Properties of Ruthenium(II) 4,5-Diazafluorenone Complexes and Their Ketal Derivatives", INORGANIC CHEMISTRY, vol. 37, no. 8, 1 April 1998 (1998-04-01), pages 2051 - 2059, XP055082682, ISSN: 0020-1669, DOI: 10.1021/ic970987e *

Also Published As

Publication number Publication date
EP2560977A1 (de) 2013-02-27
WO2011133104A1 (en) 2011-10-27

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Ipc: C07F 1/10 20060101AFI20131011BHEP

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Ipc: A61K 33/38 20060101ALI20131011BHEP

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