EP2558479A4 - Verfahren zum verbesserten nachweis einer b-zellen-immunglobulin-gen-rekombination - Google Patents

Verfahren zum verbesserten nachweis einer b-zellen-immunglobulin-gen-rekombination

Info

Publication number
EP2558479A4
EP2558479A4 EP11763339.6A EP11763339A EP2558479A4 EP 2558479 A4 EP2558479 A4 EP 2558479A4 EP 11763339 A EP11763339 A EP 11763339A EP 2558479 A4 EP2558479 A4 EP 2558479A4
Authority
EP
European Patent Office
Prior art keywords
immunoglobulin gene
gene recombination
cell immunoglobulin
improving detection
improving
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP11763339.6A
Other languages
English (en)
French (fr)
Other versions
EP2558479A1 (de
Inventor
Jian Han
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP2558479A1 publication Critical patent/EP2558479A1/de
Publication of EP2558479A4 publication Critical patent/EP2558479A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP11763339.6A 2010-03-29 2011-03-29 Verfahren zum verbesserten nachweis einer b-zellen-immunglobulin-gen-rekombination Withdrawn EP2558479A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31841710P 2010-03-29 2010-03-29
PCT/US2011/030398 WO2011123473A1 (en) 2010-03-29 2011-03-29 Method for improving detection of b cell immunoglobulin gene recombination

Publications (2)

Publication Number Publication Date
EP2558479A1 EP2558479A1 (de) 2013-02-20
EP2558479A4 true EP2558479A4 (de) 2013-09-18

Family

ID=44712594

Family Applications (1)

Application Number Title Priority Date Filing Date
EP11763339.6A Withdrawn EP2558479A4 (de) 2010-03-29 2011-03-29 Verfahren zum verbesserten nachweis einer b-zellen-immunglobulin-gen-rekombination

Country Status (6)

Country Link
EP (1) EP2558479A4 (de)
JP (1) JP2013523129A (de)
CN (1) CN103154015A (de)
AU (1) AU2011235281A1 (de)
CA (1) CA2794800A1 (de)
WO (1) WO2011123473A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104388579B (zh) * 2014-12-16 2018-11-09 上海速芯生物科技有限公司 一种转基因大豆及其衍生品种的Arm-PCR检测方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0466520A1 (de) * 1990-07-13 1992-01-15 Life Technologies Inc. Amplifikation von Nukleinsäure-Sequenzen unter Verwendung von Zufalls-Sequenzen als Primer
WO2001051661A2 (en) * 2000-01-13 2001-07-19 Amsterdam Support Diagnostics B.V. A universal nucleic acid amplification system for nucleic acids in a sample

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0466520A1 (de) * 1990-07-13 1992-01-15 Life Technologies Inc. Amplifikation von Nukleinsäure-Sequenzen unter Verwendung von Zufalls-Sequenzen als Primer
WO2001051661A2 (en) * 2000-01-13 2001-07-19 Amsterdam Support Diagnostics B.V. A universal nucleic acid amplification system for nucleic acids in a sample

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DONGEN VAN J J M ET AL: "Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: Report of the BIOMED-2 Concerted Action BMH4-CT98-3936", LEUKEMIA, MACMILLAN PRESS LTD, US, vol. 17, no. 12, 1 December 2003 (2003-12-01), pages 2257 - 2317, XP002287366, ISSN: 0887-6924, DOI: 10.1038/SJ.LEU.2403202 *
ESSONO S ET AL: "A general method allowing the design of oligonucleotide primers to amplify the variable regions from immunoglobulin cDNA", JOURNAL OF IMMUNOLOGICAL METHODS, ELSEVIER SCIENCE PUBLISHERS B.V.,AMSTERDAM, NL, vol. 279, no. 1-2, 1 August 2003 (2003-08-01), pages 251 - 266, XP004455324, ISSN: 0022-1759, DOI: 10.1016/S0022-1759(03)00242-4 *
See also references of WO2011123473A1 *

Also Published As

Publication number Publication date
CA2794800A1 (en) 2011-10-06
JP2013523129A (ja) 2013-06-17
CN103154015A (zh) 2013-06-12
AU2011235281A1 (en) 2012-11-22
WO2011123473A1 (en) 2011-10-06
EP2558479A1 (de) 2013-02-20

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Legal Events

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A4 Supplementary search report drawn up and despatched

Effective date: 20130816

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Ipc: C12Q 1/68 20060101AFI20130809BHEP

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Effective date: 20140314