EP2558479A4 - Method for improving detection of b cell immunoglobulin gene recombination - Google Patents
Method for improving detection of b cell immunoglobulin gene recombinationInfo
- Publication number
- EP2558479A4 EP2558479A4 EP11763339.6A EP11763339A EP2558479A4 EP 2558479 A4 EP2558479 A4 EP 2558479A4 EP 11763339 A EP11763339 A EP 11763339A EP 2558479 A4 EP2558479 A4 EP 2558479A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- immunoglobulin gene
- gene recombination
- cell immunoglobulin
- improving detection
- improving
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31841710P | 2010-03-29 | 2010-03-29 | |
PCT/US2011/030398 WO2011123473A1 (en) | 2010-03-29 | 2011-03-29 | Method for improving detection of b cell immunoglobulin gene recombination |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2558479A1 EP2558479A1 (en) | 2013-02-20 |
EP2558479A4 true EP2558479A4 (en) | 2013-09-18 |
Family
ID=44712594
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP11763339.6A Withdrawn EP2558479A4 (en) | 2010-03-29 | 2011-03-29 | Method for improving detection of b cell immunoglobulin gene recombination |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP2558479A4 (en) |
JP (1) | JP2013523129A (en) |
CN (1) | CN103154015A (en) |
AU (1) | AU2011235281A1 (en) |
CA (1) | CA2794800A1 (en) |
WO (1) | WO2011123473A1 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104388579B (en) * | 2014-12-16 | 2018-11-09 | 上海速芯生物科技有限公司 | A kind of Arm-PCR detection methods of genetically engineered soybean and its derived varieties |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0466520A1 (en) * | 1990-07-13 | 1992-01-15 | Life Technologies Inc. | Amplification of nucleic acid sequences using oligonucleotides of random sequence as primers |
WO2001051661A2 (en) * | 2000-01-13 | 2001-07-19 | Amsterdam Support Diagnostics B.V. | A universal nucleic acid amplification system for nucleic acids in a sample |
-
2011
- 2011-03-29 WO PCT/US2011/030398 patent/WO2011123473A1/en active Application Filing
- 2011-03-29 AU AU2011235281A patent/AU2011235281A1/en not_active Abandoned
- 2011-03-29 CN CN2011800244208A patent/CN103154015A/en active Pending
- 2011-03-29 CA CA2794800A patent/CA2794800A1/en not_active Abandoned
- 2011-03-29 EP EP11763339.6A patent/EP2558479A4/en not_active Withdrawn
- 2011-03-29 JP JP2013502769A patent/JP2013523129A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0466520A1 (en) * | 1990-07-13 | 1992-01-15 | Life Technologies Inc. | Amplification of nucleic acid sequences using oligonucleotides of random sequence as primers |
WO2001051661A2 (en) * | 2000-01-13 | 2001-07-19 | Amsterdam Support Diagnostics B.V. | A universal nucleic acid amplification system for nucleic acids in a sample |
Non-Patent Citations (3)
Title |
---|
DONGEN VAN J J M ET AL: "Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: Report of the BIOMED-2 Concerted Action BMH4-CT98-3936", LEUKEMIA, MACMILLAN PRESS LTD, US, vol. 17, no. 12, 1 December 2003 (2003-12-01), pages 2257 - 2317, XP002287366, ISSN: 0887-6924, DOI: 10.1038/SJ.LEU.2403202 * |
ESSONO S ET AL: "A general method allowing the design of oligonucleotide primers to amplify the variable regions from immunoglobulin cDNA", JOURNAL OF IMMUNOLOGICAL METHODS, ELSEVIER SCIENCE PUBLISHERS B.V.,AMSTERDAM, NL, vol. 279, no. 1-2, 1 August 2003 (2003-08-01), pages 251 - 266, XP004455324, ISSN: 0022-1759, DOI: 10.1016/S0022-1759(03)00242-4 * |
See also references of WO2011123473A1 * |
Also Published As
Publication number | Publication date |
---|---|
CA2794800A1 (en) | 2011-10-06 |
AU2011235281A1 (en) | 2012-11-22 |
WO2011123473A1 (en) | 2011-10-06 |
CN103154015A (en) | 2013-06-12 |
JP2013523129A (en) | 2013-06-17 |
EP2558479A1 (en) | 2013-02-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20121026 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20130816 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12Q 1/68 20060101AFI20130809BHEP |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20140314 |