EP2538945A4 - Oral b12 therapy - Google Patents
Oral b12 therapyInfo
- Publication number
- EP2538945A4 EP2538945A4 EP11747966.7A EP11747966A EP2538945A4 EP 2538945 A4 EP2538945 A4 EP 2538945A4 EP 11747966 A EP11747966 A EP 11747966A EP 2538945 A4 EP2538945 A4 EP 2538945A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- therapy
- oral
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/609—Amides, e.g. salicylamide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7135—Compounds containing heavy metals
- A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Molecular Biology (AREA)
- Physiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP15201219.1A EP3028709B1 (en) | 2010-02-24 | 2011-02-23 | Oral b12 therapy |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30783610P | 2010-02-24 | 2010-02-24 | |
PCT/US2011/025864 WO2011106378A2 (en) | 2010-02-24 | 2011-02-23 | Oral b12 therapy |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP15201219.1A Division EP3028709B1 (en) | 2010-02-24 | 2011-02-23 | Oral b12 therapy |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2538945A2 EP2538945A2 (en) | 2013-01-02 |
EP2538945A4 true EP2538945A4 (en) | 2013-07-24 |
Family
ID=44477007
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP15201219.1A Active EP3028709B1 (en) | 2010-02-24 | 2011-02-23 | Oral b12 therapy |
EP11747966.7A Ceased EP2538945A4 (en) | 2010-02-24 | 2011-02-23 | Oral b12 therapy |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP15201219.1A Active EP3028709B1 (en) | 2010-02-24 | 2011-02-23 | Oral b12 therapy |
Country Status (16)
Country | Link |
---|---|
US (3) | US20110207693A1 (en) |
EP (2) | EP3028709B1 (en) |
JP (3) | JP2013520511A (en) |
KR (1) | KR20130026429A (en) |
AR (1) | AR080292A1 (en) |
AU (1) | AU2011220867B2 (en) |
BR (1) | BR112012021401B1 (en) |
CA (2) | CA2790708A1 (en) |
CL (1) | CL2012002358A1 (en) |
CO (1) | CO6602160A2 (en) |
HK (1) | HK1225609A1 (en) |
MX (1) | MX2012009914A (en) |
NZ (2) | NZ701274A (en) |
RU (1) | RU2576511C2 (en) |
TW (1) | TWI590829B (en) |
WO (1) | WO2011106378A2 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10357496B2 (en) | 2011-11-05 | 2019-07-23 | South Alabama Medical Science Foundation | Methods, formulations, and kits for rapidly repleting folate levels in women |
TWI829687B (en) * | 2018-05-07 | 2024-01-21 | 丹麥商諾佛 儂迪克股份有限公司 | Solid compositions comprising a glp-1 agonist and a salt of n-(8-(2-hydroxybenzoyl)amino)caprylic acid |
CN111517980B (en) * | 2020-05-14 | 2021-02-09 | 台州浦凯医药科技有限公司 | N- [8- (2-hydroxybenzoyl) amino ] caprylic acid monopotassium crystal type compound, preparation method and application |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5665379A (en) * | 1990-09-28 | 1997-09-09 | Pharmacia & Upjohn Aktiebolag | Lipid particle forming matrix, preparation and use thereof |
US5474978A (en) * | 1994-06-16 | 1995-12-12 | Eli Lilly And Company | Insulin analog formulations |
US5650386A (en) * | 1995-03-31 | 1997-07-22 | Emisphere Technologies, Inc. | Compositions for oral delivery of active agents |
CA2266412A1 (en) * | 1996-09-18 | 1998-03-26 | William J. Sarill | Compositions containing cobalamin and amino acids |
US5773647A (en) * | 1997-02-07 | 1998-06-30 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
US6117868A (en) * | 1998-09-16 | 2000-09-12 | Ed. Geistlich Sohne Ag Fur Chemische Industrie | Treatment of gastrointestinal ulcers or gastritis caused by microbial infection |
ES2235854T3 (en) * | 1999-04-05 | 2005-07-16 | Emisphere Technologies, Inc. | DISODIC SALTS, MONOHIDRATES AND ETHANOL SOLVATES TO CONTRIBUTE ACTIVE AGENTS. |
CA2402719C (en) * | 2000-03-21 | 2012-03-20 | Emisphere Technologies, Inc. | Method of preparing alkylated salicylamides via a dicarboxylate intermediate |
US6693094B2 (en) * | 2001-03-22 | 2004-02-17 | Chrono Rx Llc | Biguanide and sulfonylurea formulations for the prevention and treatment of insulin resistance and type 2 diabetes mellitus |
WO2002087593A1 (en) * | 2001-04-25 | 2002-11-07 | Cobalz Limited | A method for treating or preventing a functional vitamin b12 deficiency in an individual and to medical compositions for use in said method |
US20050054557A1 (en) * | 2002-05-09 | 2005-03-10 | Goldberg Michael M. | Compositions for delivering parathyroid hormone and calcitonin |
TW200403052A (en) * | 2002-07-17 | 2004-03-01 | Novartis Ag | Use of organic compounds |
KR20050046776A (en) * | 2002-09-13 | 2005-05-18 | 사이덱스 인크 | Capsules containing aqueous fill compositions stabilized with derivatized cyclodextrin |
DE10311089A1 (en) * | 2003-03-13 | 2004-09-23 | Roche Diagnostics Gmbh | Determining disorders, specifically deficiency, of Vitamin B12 and/or folic acid, by measuring levels of holotranscobalamin II, homocysteine, methylmalonic acid and optionally cystathionine |
DE602004023093D1 (en) * | 2003-07-11 | 2009-10-22 | Novartis Ag | N WITH A DISPENSER IN MICRONIZED FORM |
US20050054731A1 (en) * | 2003-09-08 | 2005-03-10 | Franco Folli | Multi-system therapy for diabetes, the metabolic syndrome and obesity |
CA2563681C (en) * | 2004-05-06 | 2015-11-03 | Emisphere Technologies, Inc. | Crystalline polymorphic forms of monosodium n-[8-(2-hydroxybenzoyl)amino]caprylate |
WO2006020291A2 (en) * | 2004-08-02 | 2006-02-23 | Bebaas, Inc. | Vitamin b12 compositions |
US20060078623A1 (en) * | 2004-08-13 | 2006-04-13 | Emisphere Technologies, Inc. | Pharmaceutical formulations containing microparticles or nanoparticles of a delivery agent |
BRPI0516011A (en) * | 2004-09-24 | 2008-08-19 | Amgen Inc | modified fc molecules |
US20060116334A1 (en) * | 2004-12-01 | 2006-06-01 | Curt Hendrix | Folate based composition for treatment of the cardiovascular system |
CN101296694A (en) * | 2005-11-04 | 2008-10-29 | 真塔公司 | Pharmaceutical gallium compositions and methods |
BRPI0601834A (en) * | 2006-03-30 | 2007-11-27 | Ricardo De Souza Pereira | Dietary supplementation to cure or regress symptoms of gastroesophageal reflux, gastritis and ulcers |
DE102007005952A1 (en) * | 2007-02-06 | 2008-08-07 | BSH Bosch und Siemens Hausgeräte GmbH | Refrigerating appliance with shelves suspended from a rail |
US7943163B2 (en) * | 2007-08-22 | 2011-05-17 | Response Scientific, Inc. | Medical food or nutritional supplement, method of manufacturing same, and method of managing diabetes |
JP5555634B2 (en) * | 2007-11-02 | 2014-07-23 | エミスフェア テクノロジーズ インコーポレイティッド | Method for treating vitamin B12 deficiency |
-
2011
- 2011-02-23 AR ARP110100553A patent/AR080292A1/en not_active Application Discontinuation
- 2011-02-23 JP JP2012555099A patent/JP2013520511A/en active Pending
- 2011-02-23 CA CA2790708A patent/CA2790708A1/en not_active Abandoned
- 2011-02-23 RU RU2012136176/15A patent/RU2576511C2/en active
- 2011-02-23 EP EP15201219.1A patent/EP3028709B1/en active Active
- 2011-02-23 NZ NZ701274A patent/NZ701274A/en not_active IP Right Cessation
- 2011-02-23 NZ NZ602032A patent/NZ602032A/en not_active IP Right Cessation
- 2011-02-23 CA CA2996757A patent/CA2996757A1/en not_active Abandoned
- 2011-02-23 MX MX2012009914A patent/MX2012009914A/en unknown
- 2011-02-23 TW TW100105996A patent/TWI590829B/en not_active IP Right Cessation
- 2011-02-23 BR BR112012021401A patent/BR112012021401B1/en not_active IP Right Cessation
- 2011-02-23 US US13/033,118 patent/US20110207693A1/en not_active Abandoned
- 2011-02-23 AU AU2011220867A patent/AU2011220867B2/en not_active Ceased
- 2011-02-23 WO PCT/US2011/025864 patent/WO2011106378A2/en active Application Filing
- 2011-02-23 EP EP11747966.7A patent/EP2538945A4/en not_active Ceased
- 2011-02-23 KR KR1020127024905A patent/KR20130026429A/en active Search and Examination
-
2012
- 2012-08-24 CL CL2012002358A patent/CL2012002358A1/en unknown
- 2012-09-17 CO CO12159803A patent/CO6602160A2/en not_active Application Discontinuation
-
2013
- 2013-05-13 HK HK16113866A patent/HK1225609A1/en unknown
-
2015
- 2015-07-30 JP JP2015150644A patent/JP2015193660A/en active Pending
- 2015-11-30 US US14/954,393 patent/US20160074420A1/en not_active Abandoned
-
2017
- 2017-03-07 JP JP2017042569A patent/JP2017101081A/en active Pending
-
2020
- 2020-03-09 US US16/812,888 patent/US20200206247A1/en not_active Abandoned
Non-Patent Citations (2)
Title |
---|
CASTELLI M CRISTINA ET AL: "SNAC co-formulation produces significant enhancement of oral vitaminB12 bioavailability in rats", FASEB JOURNAL, FED. OF AMERICAN SOC. FOR EXPERIMENTAL BIOLOGY, US, vol. 22, no. Meeting Abstract Supplement, April 2008 (2008-04-01), XP009170259, ISSN: 0892-6638 * |
HART N J: "Eligen(R) vitamin B12 & the SNAC carrier for oral delivery", DRUG DELIVERY TECHNOLOGY, DRUG DELIVERY TECHNOLOGY, US, vol. 9, no. 9, October 2009 (2009-10-01), pages 28 - 34, XP009170295, ISSN: 1537-2898 * |
Also Published As
Publication number | Publication date |
---|---|
NZ602032A (en) | 2014-11-28 |
CA2996757A1 (en) | 2011-09-01 |
AU2011220867A1 (en) | 2012-09-20 |
CL2012002358A1 (en) | 2012-12-14 |
EP3028709A1 (en) | 2016-06-08 |
JP2015193660A (en) | 2015-11-05 |
AR080292A1 (en) | 2012-03-28 |
BR112012021401A2 (en) | 2016-10-25 |
RU2576511C2 (en) | 2016-03-10 |
WO2011106378A3 (en) | 2011-11-24 |
US20160074420A1 (en) | 2016-03-17 |
US20110207693A1 (en) | 2011-08-25 |
KR20130026429A (en) | 2013-03-13 |
AU2011220867B2 (en) | 2014-05-15 |
TWI590829B (en) | 2017-07-11 |
RU2012136176A (en) | 2014-03-27 |
CA2790708A1 (en) | 2011-09-01 |
JP2017101081A (en) | 2017-06-08 |
TW201200139A (en) | 2012-01-01 |
EP2538945A2 (en) | 2013-01-02 |
JP2013520511A (en) | 2013-06-06 |
CO6602160A2 (en) | 2013-01-18 |
WO2011106378A2 (en) | 2011-09-01 |
EP3028709B1 (en) | 2019-08-28 |
HK1225609A1 (en) | 2017-09-15 |
US20200206247A1 (en) | 2020-07-02 |
NZ701274A (en) | 2016-03-31 |
MX2012009914A (en) | 2013-03-05 |
BR112012021401B1 (en) | 2019-12-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20120924 |
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AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
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DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20130624 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 45/06 20060101ALI20130618BHEP Ipc: A61K 31/714 20060101AFI20130618BHEP |
|
REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 1177892 Country of ref document: HK |
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17Q | First examination report despatched |
Effective date: 20140429 |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED |
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Effective date: 20151115 |
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