EP2536688A4 - Stable dosage forms of levomilnacipran - Google Patents
Stable dosage forms of levomilnacipranInfo
- Publication number
- EP2536688A4 EP2536688A4 EP11733447.4A EP11733447A EP2536688A4 EP 2536688 A4 EP2536688 A4 EP 2536688A4 EP 11733447 A EP11733447 A EP 11733447A EP 2536688 A4 EP2536688 A4 EP 2536688A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- levomilnacipran
- dosage forms
- stable dosage
- stable
- forms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29489810P | 2010-01-14 | 2010-01-14 | |
US12/941,293 US8865937B2 (en) | 2009-11-06 | 2010-11-08 | Crystalline forms of (1S,2R)-2-(amino methyl)-N,N-diethyl-1-phenyl cyclopropane carboxamide |
PCT/US2011/021315 WO2011088331A1 (en) | 2010-01-14 | 2011-01-14 | Stable dosage forms of levomilnacipran |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2536688A1 EP2536688A1 (en) | 2012-12-26 |
EP2536688A4 true EP2536688A4 (en) | 2014-04-02 |
Family
ID=44304671
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP11733447.4A Withdrawn EP2536688A4 (en) | 2010-01-14 | 2011-01-14 | Stable dosage forms of levomilnacipran |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP2536688A4 (en) |
JP (1) | JP2013517290A (en) |
CA (1) | CA2790933A1 (en) |
WO (1) | WO2011088331A1 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2978350B1 (en) * | 2011-07-28 | 2013-11-08 | Pf Medicament | LEVOMILNACIPRAN-BASED MEDICINAL PRODUCT FOR FUNCTIONAL REHABILITATION AFTER ACUTE NEUROLOGICAL ACCIDENT |
CN110711185A (en) * | 2018-07-11 | 2020-01-21 | 北京万全德众医药生物技术有限公司 | Levomilnacipran sustained-release capsule |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998008495A1 (en) * | 1996-08-28 | 1998-03-05 | Pierre Fabre Medicament | Galenic formula with extended release of milnacipran |
US20040162334A1 (en) * | 2003-02-14 | 2004-08-19 | Jean Deregnaucourt | Use of the dextrogyral enantiomer of milnacipran for the preparation of a drug |
WO2009127737A1 (en) * | 2008-04-18 | 2009-10-22 | Pierre Fabre Medicament | Use of enantiomer (1s, 2r) of milnacipran hydrochloride for the preventive treatment of suicidal behaviour in depressed patients |
WO2010129689A1 (en) * | 2009-05-05 | 2010-11-11 | Forest Laboratories Holdings Limited | Milnacipran formulations |
WO2011057176A1 (en) * | 2009-11-06 | 2011-05-12 | Forest Laboratories Holding Limited | Novel crystalline forms of (1s,2r)-2-(amino methyl)-n,n-diethyl-1-phenyl cyclopropane carboxamide |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040034101A1 (en) * | 2001-11-05 | 2004-02-19 | Cypress Bioscience, Inc. | Treatment and prevention of depression secondary to pain (DSP) |
AR042806A1 (en) * | 2002-12-27 | 2005-07-06 | Otsuka Pharma Co Ltd | COMBINATION OF CARBOSTIRILE DERIVATIVES AND INHIBITORS OF SEROTONINE REABSORTION FOR THE TREATMENT OF ANIMO DISORDERS |
ES2310715T3 (en) * | 2003-02-14 | 2009-01-16 | Pierre Fabre Medicament | USE OF THE MILLER (1S, 2R) OF THE MILNACIPRAN FOR THE PREPARATION OF A MEDICINAL PRODUCT |
JP5036029B2 (en) * | 2005-06-10 | 2012-09-26 | 旭化成ファーマ株式会社 | Stabilized milnacipran formulation |
JP2008273867A (en) * | 2007-04-27 | 2008-11-13 | Asahi Kasei Pharma Kk | Preparation for transmucosal administration |
-
2011
- 2011-01-14 JP JP2012549117A patent/JP2013517290A/en active Pending
- 2011-01-14 EP EP11733447.4A patent/EP2536688A4/en not_active Withdrawn
- 2011-01-14 CA CA2790933A patent/CA2790933A1/en not_active Abandoned
- 2011-01-14 WO PCT/US2011/021315 patent/WO2011088331A1/en active Application Filing
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998008495A1 (en) * | 1996-08-28 | 1998-03-05 | Pierre Fabre Medicament | Galenic formula with extended release of milnacipran |
US20040162334A1 (en) * | 2003-02-14 | 2004-08-19 | Jean Deregnaucourt | Use of the dextrogyral enantiomer of milnacipran for the preparation of a drug |
WO2009127737A1 (en) * | 2008-04-18 | 2009-10-22 | Pierre Fabre Medicament | Use of enantiomer (1s, 2r) of milnacipran hydrochloride for the preventive treatment of suicidal behaviour in depressed patients |
WO2010129689A1 (en) * | 2009-05-05 | 2010-11-11 | Forest Laboratories Holdings Limited | Milnacipran formulations |
WO2011057176A1 (en) * | 2009-11-06 | 2011-05-12 | Forest Laboratories Holding Limited | Novel crystalline forms of (1s,2r)-2-(amino methyl)-n,n-diethyl-1-phenyl cyclopropane carboxamide |
Non-Patent Citations (1)
Title |
---|
See also references of WO2011088331A1 * |
Also Published As
Publication number | Publication date |
---|---|
EP2536688A1 (en) | 2012-12-26 |
JP2013517290A (en) | 2013-05-16 |
CA2790933A1 (en) | 2011-07-21 |
WO2011088331A1 (en) | 2011-07-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20120718 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20140303 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 9/48 20060101AFI20140225BHEP |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20141001 |