EP2480272A2

EP2480272A2 - Injection device

Info

Publication number: EP2480272A2
Application number: EP10757045A
Authority: EP
Inventors: Joachim Keitel
Original assignee: Haselmeier AG
Current assignee: Haselmeier AG
Priority date: 2009-09-26
Filing date: 2010-09-21
Publication date: 2012-08-01
Also published as: US20130030383A1; WO2011035877A3; JP2013505748A; WO2011035877A2; DE102009048497A1; CA2773605A1

Abstract

The invention relates to an injection device comprises a housing (34), and a carpule container (44) for accommodating a carpule (50) having a fluid (52) to be injected, and a piston (48) displaceable in said carpule (50). The device further comprises a piston rod (38) for displacing the piston (48) of a carpule (50) inserted in the carpule container (44) during an injection, thus pressing fluid (52) out of the carpule (50). The piston rod (38) has an external thread (40), which engages with the internal thread of a component (150) arranged in the housing (34). The device further comprises a gear unit (98) provided with a first component (68), which is arranged rotatably relative to the housing (34), but axially non-displaceably, and a second component (92), which is connected in a non-rotatable but axially displaceable manner to the piston rod (38), so that the first component (68), the second component (92), and the piston rod (38) can jointly rotate relative to the housing (34) as long as an axial displacement of the piston rod (38) is not obstructed. In the event that the piston rod (38) is prevented by the piston (48) of a carpule (58) from further displacement in the direction of said piston (48), the first component (68) and the second component (92) move relative to one another, thus displacing the second component (92) in a position in which said second component and the piston rod (38) non-rotatably connected thereto are prevented from a rotation relative to the housing (34).

Description

injection device

The invention relates to an injection device, which preferably serves, from a

Medication reservoir, also referred to as a carpule, for making one or more injections, depending on the patient's need for medication. The injections are made by a hypodermic needle, which is also called a cannula.

A carpule has a displaceable piston, usually made of an elastomer, and this piston is also called a plug. During injection, the plug is pushed by a piston rod, which is also referred to as dosing, in the direction of the front, ie towards the patient to squeeze drug through the injection needle.

In conventional designs of such injection devices, the desired movement of the piston can be set in increments of 0.14 mm. Thus, to achieve the desired precision in the amount of injected drug, it is necessary that the position of the plunger be accurately known at the beginning of an injection.

In many injection devices, the carpule is replaceable, i. When the contents of a carpule are exhausted, a new one is inserted into the injection device. After inserting a new carpule, the position of the piston in it is not known exactly. Even with cartridges that are filled mechanically with a constant volume, the position of the piston can fluctuate by about ± 0.5 mm.

Therefore, in the case of a pen-type injector, where the cartridge can be exchanged, the piston rod must be "turned on" to the piston of the carpule, ie there must be no clearance between the piston rod and the piston after starting in that after inserting the carpule and after screwing on an injection needle the patient repeatedly sets a small injection dose and makes "injections" into the air until the piston rod fits snugly against the piston and medicament for the first time emerges from the injection needle. This process is called priming. In practice, it is important that this process is as simple and obvious as he is otherwise happy to forget. Pen injectors usually have a holder in which the carpule is inserted and which is attached to the pen injector. This holder, which can be described as a carpule container, is formed at its near-patient, front end so that an injection needle can be attached, for example by means of a bayonet connection or a screw thread.

It is therefore an object of the invention to provide a new injection device.

According to the invention, this object is achieved by the subject matter of claim 1.

Further details and advantageous developments of the invention will become apparent from the following illustrated and described, in no way as a limitation to be understood embodiments, and from the dependent claims. It shows:

Fig. 1 is an injection device 28 in the form of a so-called. Peninjektors, seen in the direction of

Arrow I of Fig. 2,

Fig. 2, the injection device of FIG. 1, seen in the direction of the arrow II of Fig. 1, wherein the

Cartridge partially filled with the drug,

Fig. 3, the injection device of Fig. 1 and 2, in which the supply of drug

is used, and in which therefore the empty carpule has to be exchanged for a full carpule,

Fig. 4 the same injection device, wherein the piston rod by rotation of the

Cartridge container - in the direction of an arrow 58 - screwed back to the rear to allow the replacement of the empty carpule,

5, the injection device of FIG. 4, in which the carpule container (which still contains the empty carpule) is removed, 6, the injection apparatus of FIG. 5, in which the old carpule is removed from the carpule container and replaced by a new,

Fig. 7, the injection device of FIG. 6, wherein the carpule container on the housing of the

Injection device is attached,

Fig. 8, the injection device of Fig. 7, wherein the piston rod by turning the

Karpulencontainers is brought to the piston in the new carpule and rests against this without play,

FIG. 9 shows a representation analogous to FIG. 8, but on an enlarged scale; FIG. this figure serves for

Explanation that there must be no air gap between the piston in the carpule and a plate attached to the piston rod,

1 0 is a side view of a carpule container 44, seen in the direction of the arrow X of FIG. 1 1,

Fig. 1 1 is a longitudinal section, as seen along the line XI - XI of Fig. 10, wherein in the

Cartridge container 44 is a filled carpule 50,

12 is a perspective view of the carpule container 44 of FIG. 10 and 1 1,

13 is a three-dimensional view of a first component 68, which is used to attach the

Karpulencontainers 44 on the housing 34 and here carries three ramps that serve to support the priming,

14 is a perspective view of the component 68 of FIG. 13, but seen from the

Side of the ramps,

Fig. 1 5 is a plan view of the component 68 of FIGS. 13 and 14, seen in the direction of

Arrow XV of FIG. 14, Fig. 1 6 is a three-dimensional view of a second component 92, which also carries three ramps, which with the ramps of the component of FIG. 13 to 1 fifth

work together

Fig. 17 is a plan view from below of the second component 92, seen in the direction of the arrow

XVII of Fig. 18,

18 is a side view, as seen in the direction of arrow XVIII of FIG. 17,

19 is a plan view of the component 92 of FIG. 16, seen in the direction of the arrow XIX of FIGS. 16 and 18,

20 shows a three-dimensional representation of the second component 92 according to FIGS. 16 to 19 and a compression spring acting on this component,

Fig. 21 is a view similar to Figure 20 but in side view. the representation of the second

Component 92 corresponds approximately to the representation of FIG. 18,

Fig. 22 is a plan view of the housing 34, seen in the direction of arrow XXII the

Fig. 21,

Fig. 23 is an exploded view for explaining the interaction of the in the

parts shown in the preceding figures,

FIG. 24 is a perspective view analogous to FIG. 23; FIG.

25 is an illustration which serves to explain the employment of the piston rod 38 (FIG. 9) against the piston 48 of a carpule 50 and the simultaneous locking of the second component 92 against rotation, FIG. FIG. 26 is an illustration showing the locked state of the second member 92, which also locks the piston rod 38 (FIG. 9) against rotation but can be moved in the axial direction.

Fig. 27 is an illustration showing the cancellation of the locking of the second member 92 before a change of the carpule; Here, the carpule container 44 is rotated in the direction of the arrow 58;

28 is a longitudinal section, as seen in the direction of the arrows XXVIII-XXVIII of FIG. 25,

29 is a longitudinal section, as seen in the direction of the arrows XXIX-XXIX of FIG. 26,

Fig. 30 is a plan view of the housing 34, seen in the direction of arrow XXX of

Fig. 31,

Fig. 31 is an exploded view of a simplified embodiment of the

Injection device,

32 shows a representation analogous to FIG. 31, but in a three-dimensional representation,

Fig. 33 shows a variant of FIG. 16 of the embodiment according to FIGS. 16 to 29, the

Especially suitable for injection devices, in which no replacement of the carpule is possible, namely a component with three ramps 124, which cooperate with the ramps of the component of FIGS. 13 to 15,

Fig. 34 is a plan view from below of the second component 92, viewed in the direction of the arrow

XXXIV of Fig. 35,

35 is a side view, as viewed in the direction of the arrow XXXV of Fig. 34, 36 is a plan view of the component of FIGS. 33 to 35, seen in the direction of the arrow XXXVI of FIG. 35,

Fig. 37 shows a variant of the second component 92, with a reduced compared to FIG. 35

Thread pitch of its ramps 124 ',

FIG. 38 shows a plan view of the part 92, seen in the direction of the arrow XXXVIII of FIG. 37, FIG.

39 is a highly schematic representation of important parts of the injection device here in the process of "adjusting" after a carpule change,

Fig. 40 the completion of Anstellens, wherein the plate 46 'of the piston rod 38 against the

Plunger 48 is applied and the piston rod 38 is blocked against rotation, and

Fig. 41 shows a process during the carpule change, in which the carpule container 44 in

Direction of an arrow 58 is rotated to move the plate 46 'down.

Figs. 1 and 2 show an injection device 28, which is also referred to as a pen-injector because of its small size. At the rear, ie on its side away from the patient, it has an adjustment knob 30 for setting a desired injection dose (by turning the knob 30), the set dose being displayed in a window 32. When adjusting the knob 30 is rotated out of a housing 34, and in an injection, the patient presses in the direction of an arrow 36 on the button 30, so the patient. In this way, a piston rod 38, which is provided with an external thread 40, displaced in the direction of an arrow 42 forward in the direction of the patient, which one must think in Figs. 1 to 12 and 23 to 32 above. The external thread 40 is shown as a left-hand thread.

2 and 3, the piston rod 38 is in a carpule container 44 which is provided with two opposite windows 46.

Fig. 3 shows the pen-injector 28 with an empty carpule 50, whose shape is best seen in Fig. 1 1. The injection liquid 52 (Figures 2, 6, 7, 8, 9, 11) is consumed and the piston rod 38 is in its foremost position. Before now a fully filled carpule 50 can be inserted, as shown in FIG. 1 1, the piston rod 38 must be brought into their rearmost position.

In some pen injectors, this is done by unscrewing the carpule container 44 and then rotating the piston rod 38 back by turning it on a separate component called the return ring. In other pen injectors, the piston rod 38 is simply pressed by hand into the housing 34 after removing the carpule container 44.

In the injection device shown, the piston rod 38 by turning the

Cartridge container 44 screwed back, here by turning counterclockwise, see. the arrow 58 in Fig. 4. (The direction of rotation is indicated from view from the front side of the injector 28, so from a top view.)

When the piston rod 38 has reached its rearmost position, the carpule container 44 can be removed (FIG. 5), and the empty carpule 50 can be replaced by a full one, cf. Fig. 6. The carpule container 44 is then attached to the housing 34, see. Fig. 7. By turning opposite to the direction 58 (Fig. 4), the piston rod 38 is screwed forward, so here by a clockwise rotation, see. the arrow 60 of FIG. 8.

As soon as the plate 46 'of the piston rod 38 reaches the piston 48, cf. Fig. 8, locks the system automatically, i. further rotation of the carpule container 44 in the clockwise direction 60 becomes impossible. To turn the carpule container anticlockwise, cf. the arrow 58 of FIG. 4, now an increased torque must be expended.

In this way it is prevented that the patient inadvertently rotates the carpule container 44 in the counterclockwise direction, although he still wants to take injections from the currently inserted carpule 50. In this case, a gap 62 (FIG. 9) would arise between the plate 46 'and the piston 48, so that the latter would be moved forwards by a path through the plate 46' of the piston rod 38 during a subsequent injection Gap 62 is too small, so when injecting a

Amount of liquid would be injected, which is correspondingly too small. Therefore, the correct "turn on" of the plate 46 'on the piston 48 is very important. The carpule container 44 can thus only in the locked state (FIG. 8) with increased

Torque can be rotated counterclockwise. This provides protection against the accidental initiation of a carpule change (Figure 4), in effect comparable to the protection that is common in comparable pen injectors.

After the carpule container 44 is locked, as described below, the patient may begin the injections without having to specially prime the pen injector again. This results in a very obvious and easy to understand

Service.

Figs. 10 to 12 are used to explain the carpule container 44. This has at its distal end 63 a pin 64, the bayonet connection with a

corresponding recess 66 of a first component 68 is used, which is shown in Figs. 13 to 15 and 23 to 32.

For locking, as shown in FIG. 25, the pin 64 from above along a path 70 in the

Recess 66 introduced and then brought by twisting (to the left) via a locking lug 74 along a path 72 in the detent position shown in Fig. 25, 26 and 27. - By an axially extending recess 76 (Fig. 26), the lower boundary 7 8 (Fig. 26) of the recess 66 is resiliently resilient to allow a latching connection.

The component 68 has a hollow cylindrical outer wall 80, and in this elastically resilient guide members 82 are incorporated, which in the housing 34, an annular groove 84 (Fig. 20, 24, 28, 29) is associated. During assembly, the guide members 82 engage in this annular groove 84, and the component 68 is then rotatably guided by the guide members 82 in the annular groove 84 of the housing 34, but can not move axially relative to the housing 34. The component 68 in turn via the bayonet connection 64, 66 with the carpule container 44 fixed, but releasably connected.

As shown in FIG. 14, the component 68 has, subsequent to the cylindrical outer wall 80, a bottom 86, in the center of which there is a recess 88 into which a collar 90 of a second component 92 protrudes, as shown in FIGS. 28, 29 Components 68 and 92 are rotatable relative to each other and also axially displaceable. The collar 90 has an axially extending recess 94, which serves for the axial guidance of the piston rod 38 and is therefore adapted to the cross-sectional shape, as shown for example in FIGS. 16, 17 and 19, so that the piston rod 38 and the second component 92 only rotate together, but can move axially relative to each other.

In contrast, while the first member 68 may rotate relative to the housing 34, but not axially displace. This then also applies to the carpule container 44 when it is engaged on part 68.

The first component 68 and the second component 92 together form a gear 98, whose function will be described below with reference to FIGS. 25 to 27. It serves to convert a relative rotation between the components 68 and 92 into an axial movement of the second member 92, which has the function of bracing the second member 92 and the piston rod 38 guided therein, e.g. by positive engagement of the component 92 with the housing 34, see. 21 to 23 and 25 to 27, or by the generation of a strong friction between the second member 92 and the housing 34, as shown in Figs. 32 to 36.

As shown in FIGS. 13 to 36, first component 68 and second component 92 are provided with ramps 104 and 118, respectively.

FIGS. 14 and 15 show by way of example three ramps 104 which are arranged on the bottom 86 of the first component 68 at equal intervals of 120 °.

If one starts from a point 105 in FIG. 15, which would correspond to three o'clock in the case of a clock, a ramp-free section 106 with an angular extent of approximately 50 ° follows in the clockwise direction. This is followed by a section 108 (e.g., 30 °) having a ramp section 110, which usually rises to a maximum in section 108.

This is followed by a flat section 12 (eg 40 °), in which the height of the ramp 104 no longer changes significantly, and at the end 14 of this section 12, the height of the ramp 104 abruptly drops to zero, ie the point 14 represents a shoulder of the ramp 104. Overall, therefore, the first component 68 has three ramps 104, three shoulders 1 14, and three ramp sections 1 10. Following the shoulder 1 14 repeats the structure described, ie at an angular distance 106 from the shoulder 1 14, the rise of the next begins

Ramp portion 1 10, as is clear from Figures 14 and 1 5.

The second component 92 (FIGS. 1 to 19) has a construction that is largely complementary thereto, as a comparison of FIGS. 15 and 19 shows. It also has three ramps 1 18.

Starting at a shoulder 120 (FIG. 19) at a position corresponding to approximately 4 o'clock, a flat area 122 (eg 50 °), as seen in the clockwise direction, is followed by a rising area 124 of the lower ramp 1 18 in FIG followed. This

Ramp area 1 24 has in this example an angular extent 126 of about 30 °, and it ends in a flat roof area with an angular extent 1 28 of e.g. 40 °, at the end of which there is again a shoulder 120.

The ramps 1 18 lie around the collar 90 around, and within the collar 90 is the recess 94 in which the piston rod 38 is guided. Thus, when the second member 92 rotates, the piston rod 38 also rotates, and this can move freely in the axial direction in the recess 94, as shown e.g. when priming is required.

On its side facing away from the ramps 1 1 8 side, the second component 92 has a coupling projection 130 which tapers frustoconically at its free end 132 and is provided with longitudinal grooves 134 for engagement in corresponding longitudinal grooves 136 of the housing 34, so that the projection 130 upon engagement is prevented in the longitudinal grooves 136 by a positive connection to a rotation. Possibly. This effect according to FIGS. 30 to 36 can also be achieved without the projection in that the second component 92 is simply pressed against a surface 140 (FIG. 32) of the housing 34 and secured there against friction by friction.

The second component 92 is urged by a spring 142 in the direction of the first

Device 68 pressed, the latter rotatable in the housing, but by the

Guide members 82 and the annular groove 84 is guided axially non-displaceable. operation

25 shows, with a clockwise rotation 60, as occurs after the insertion of a new carpule 50 (see FIG. 8), the ramps 104 of the first component 68 are located between the ramps 1 18 of the second component 92, FIG. since the latter is pressed against the first component 68 by the spring 142 (FIG. 24). As a result, the coupling member 130 is disengaged from the coupling member 136 provided in the housing 34, so that when the patient

Cartridge container 44 clockwise (arrow 60) rotates with the carpule container 44 and the first component 68 rotates with its ramps 104, and these ramps 104 engage as shown in FIG. 25 between the ramps 1 18 of the second component 92 and thereby transmit this rotational movement 60 also on the second component 92 and guided in this piston rod 38th

The latter is guided in the housing 34 in a threaded portion 1 50 (Fig. 28, 29), e.g. Part of the metering device of the injector may be and does not rotate when changing cartridges. The piston rod 38 is therefore in Fig. 28 at a rotation 60 (Fig. 25) in an upward direction, so towards the patient, moved.

As shown in FIG. 9, the piston rod 38 comes into abutment against the piston 48 in the carpule 50 by means of its plate 46 '. the injector 28 is now primed, so properly prepared for an injection.

Therefore, the piston rod 38 can not move further up, i. Although the torque in the direction of arrow 60 (Figure 25) continues to function because the patient continues to rotate the carpule container 44, as shown in Figure 26, the rotation of the second member 92 is now blocked because the piston rod 38 is against the piston 48 is present, cf. Fig. 8.

Therefore, the inclined surfaces 110 (FIGS. 14 to 16) of the ramps 104 of the first component 68 cause an axial force on the inclined surfaces 124 of the ramps 18 of the second component 92 and displace the latter, as shown in FIG. 26, against the force This results in a coupling between the projection 1 30 (FIG. 21) and the longitudinal grooves 136 in the housing 34 (FIG. 22), so that the second component 92 does not can continue to turn clockwise 60 clockwise.

Thus, the injection device 28 is now ready for use, ie the patient can normally adjust his individual injection dose and give himself injections until the contents of the carpule 50 is consumed. Thereafter, the carpule container 44 must be removed. For this purpose, this, as shown in FIG. 27, rotated in the counterclockwise direction 58. In this case, the previous coupling between the first component 68 and the second component 92, the latter is displaced by the spring 142 in the upward direction, and the shoulders 1 14 of the first component 68 come into abutment against the shoulders 120 of the second component 92, so that the latter is also driven in the counterclockwise direction 58.

As a result, the piston rod 38 is turned all the way into the housing 34, and the bayonet lock 64, 66 is released at the end of this process so that the carpule container 44 can be removed to remove the spent carpule and insert a new carpule 50, such as which has already been described with reference to FIGS. 1 to 9.

The described procedure is then repeated to re-prime the new carpule 50 and to re-prepare the injection device 28 for safe use.

For the optimization of the present invention, the slope of the ramps has also been changed.

Each of these ramps can be thought of as part of a thread whose (fictitious)

Threads have a certain slope. This thread pitch is the distance from one thread to the next and is preferably about 10 to about 20 mm.

In Fig. 38, the inner diameter a and the outer diameter b of the ramps 124 'of the part 92 are entered. Practical values may e.g. be

a = 6 mm

b = 1 1, 5 mm.

A ramp 124 'here extends over an angle beta, e.g. 40 °.

If at the employment parts 68 and 92 by 36 ° rel. twisting each other, their distance h changes

h = 360 36 ° * thread pitch ... (1). If the thread pitch is 1 5 mm, so h has about the value 1, 5 mm, which has proven in experiments as a favorable value.

The ramps 104 on the part 68 have the same shape as the ramps 124 'of the part 92 and are therefore only shown in FIGS. 39 to 41. There, the part 68 and its ramps 104 are highlighted in gray to facilitate understanding.

FIGS. 39 to 41 show highly schematic representations of the setting processes. Fig. 39 shows the setting of the plate 46 'to the piston 48. The ramps 1 18 are rotated in the direction of the arrow 60, so that they first move the plate 46' upwards in the direction of the piston 48. In Fig. 40, the plate 46 'has reached the piston 48. Therefore, now the upper ramps 1 10 are shifting relative to the lower ramps 124 'and moving the part 92 downwardly so that it now has the distance h' from the part 68 and the part 92 is blocked against rotation in the manner described , The injection device is now primed.

Fig. 41 shows the process of cartridge replacement. The carpule container 44 is rotated in the direction of the arrow 58, whereby the ramps 104 detach from the ramps 124 'and the distance between the parts 68 and 92 is h again. The part 92 is pressed by its spring 142 (see Fig. 31) toward the part 68. The ramps 104 now press with their steep flanks 1 14 against the corresponding flanks 120 (FIG. 40) of the ramps 1 10.

As the part 68 rotates together with the part 92 in the direction of the arrow 58, the plate 46 'is moved downwards, and at the end of this movement the part 68 separates from the metering part 44, as shown in Fig. 5. The operation is so very simple and obvious, and the dosing accuracy is increased accordingly.

Naturally, in the context of the present invention multiple modifications and

Modifications possible.

Claims

claims

Injection device, in particular pen injector,

with a housing (34),

and a carpule container (44) associated with this housing (34) for receiving a carpule (50) with a liquid to be injected (52) and with a piston (48) displaceable in this carpule (50),

and with a piston rod (38) which serves to displace the piston (48) of a carpule (50) inserted into the carpule container (44) during an injection and thereby to force liquid (52) out of the carpule (50),

which piston rod (38) has an external thread (40) which engages with the internal thread of a component (1 50) arranged in the housing (34),

further comprising a gear (98) having a first member (68) rotatably but axially non-displaceably disposed relative to the housing (34) and in operation connected to the carpule container (44),

and a second component (92) which is non-rotatably but axially displaceably connected to the piston rod (38),

such that the first component (68), the second component (92) and the piston rod (38) can rotate together relative to the housing (34) as long as the piston rod (38) is not hindered from axial displacement,

and

in that, when the piston rod (38) is prevented from further displacement towards the piston (48) by the piston (48) of a carpule (58), the first component (68) and the second component (92) are relative to one another move and thereby move the second component (92) in a position in which the possibility of rotation of the second component (92) and the rotatably connected to him piston rod (38) relative to the housing (34) is at least hampered.

2. Injection device according to claim 1, wherein the gear (98) has a first ramp (104) which is provided on the second component (92) facing side of the first component (68),

and a second ramp (1 18) which is provided on the side of the second component (92) facing the first component (68),

and which cooperates with the first ramp (104),

in order to change the axial distance (h) between the first component (69) and the second component (92) during a relative rotation between the first component (68) and the second component (92) and thereby the second component (92) in the Move position in which its rotation relative to the housing (34) is at least hampered.

3. Injection device according to claim 2, wherein at least one of the ramps (104, 1 18) merges into a section which is approximately perpendicular to the axis of rotation of the first component (68) to a change of the axial distance (h) between the first component (68) and the second component (92) in a predetermined range of relative rotation between the first component (68) and the second component (92) to prevent.

4. Injection device according to one of the preceding claims, wherein a spring element (142) is provided which acts on the second component (92) in the direction of the first component (68).

5. Injection device according to one of the preceding claims, wherein the second component (92) is designed as a return member for returning the piston rod (38) before a change of the carpule (50).

6. Injection device according to one of the preceding claims, wherein the first component (68) on its side facing the carpule container (44) side for releasable connection with the carpule container (44) formed (64, 66).

7. Injection device according to claim 5 or 6, wherein the first component (68) and the second component (92) have a bearing (88, 90) to each other, which allows their rotation relative to each other.

8. Injection device according to one of the preceding claims, wherein the transmission (98) is formed so that, if by a relative to the housing (34) taking place, common rotation of the first component (68), second component (92), and Piston rod (38) the latter has reached the piston (48) of a carpule (50) inserted into the carpule container (44), the second component (92) is displaceable into a blocking position, in which an engaging part (1) provided on the second component (92) 30) in a with the housing (34) rotatably connected counterpart (134) engages, and thereby blocks further rotation of the second component (92) and the non-rotatably connected to the piston rod (38).

9. Injection device according to claim 2 or 3, wherein the ramps (104, 1 18) are each formed in the manner of a (fictitious) thread turn.

10. Injection device according to claim 9, wherein the thread pitch, so the distance

between two adjacent threads, has a value of about 10 mm to about 20 mm.

1 1. Injection device according to claim 10, wherein the thread pitch has a value of about 14 mm to about 16 mm.

12. Injection device according to one of claims 2, 3, 9, 10 1 1, wherein in each case three ramps are provided on the first component (68) and on the second component (92), wherein the ramps of the first component (68) with the ramps of the second component (92) at least partially cooperate.