EP2370819A4 - Diagnostic and treatment methods for cancer based on immune inhibitors - Google Patents
Diagnostic and treatment methods for cancer based on immune inhibitorsInfo
- Publication number
- EP2370819A4 EP2370819A4 EP09830987A EP09830987A EP2370819A4 EP 2370819 A4 EP2370819 A4 EP 2370819A4 EP 09830987 A EP09830987 A EP 09830987A EP 09830987 A EP09830987 A EP 09830987A EP 2370819 A4 EP2370819 A4 EP 2370819A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- diagnostic
- treatment methods
- cancer based
- immune inhibitors
- immune
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
- G01N33/505—Cells of the immune system involving T-cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
- G01N2405/08—Sphingolipids
- G01N2405/10—Glycosphingolipids, e.g. cerebrosides, gangliosides
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11881708P | 2008-12-01 | 2008-12-01 | |
US17597709P | 2009-05-06 | 2009-05-06 | |
PCT/US2009/066262 WO2010065544A2 (en) | 2008-12-01 | 2009-12-01 | Diagnostic and treatment methods for cancer based on immune inhibitors |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2370819A2 EP2370819A2 (en) | 2011-10-05 |
EP2370819A4 true EP2370819A4 (en) | 2012-09-19 |
Family
ID=42233821
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP09830987A Withdrawn EP2370819A4 (en) | 2008-12-01 | 2009-12-01 | Diagnostic and treatment methods for cancer based on immune inhibitors |
Country Status (3)
Country | Link |
---|---|
US (1) | US20110256147A1 (en) |
EP (1) | EP2370819A4 (en) |
WO (1) | WO2010065544A2 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8536140B2 (en) * | 2004-03-12 | 2013-09-17 | Mti Meta Tech Inc. | Methods for treating inflammatory bowel disease |
CA2818536C (en) | 2010-11-25 | 2020-04-28 | Imnate Sarl | Modulation of antigen immunogenicity by addition of epitopes recognized by nkt cells |
RU2598247C2 (en) | 2010-11-25 | 2016-09-20 | Имнейт Сарл | Modulation of antigen immunogenicity by deleting epitopes recognized by nkt-cells |
WO2015051247A1 (en) * | 2013-10-03 | 2015-04-09 | University Of Maryland, Baltimore | Nanoparticle based artificial antigen presenting cell mediated activation of nkt cells |
US20170058353A1 (en) * | 2014-02-12 | 2017-03-02 | Tonya J Webb | Qpcr-based method to assess t cell function |
KR20210032011A (en) * | 2014-09-17 | 2021-03-23 | 더 존스 홉킨스 유니버시티 | Reagents and methods for identifying, enriching, and/or expanding antigen-specific t cells |
MX2021005372A (en) | 2018-11-08 | 2021-09-14 | Neximmune Inc | T cell compositions with improved phenotypic properties. |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0091005A1 (en) * | 1982-04-02 | 1983-10-12 | Sloan-Kettering Institute For Cancer Research | Method for detecting the presence of GD3 ganglioside |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4849509A (en) * | 1987-02-20 | 1989-07-18 | The Wistar Institute | Monoclonal antibodies against melanoma-associated antigens and hybrid cell lines producing these antibodies |
US5006470A (en) * | 1987-04-16 | 1991-04-09 | Sloan-Kettering Institute For Cancer Research | Human monoclonal antibodies to cell surface antigens of melanoma |
CA2078539C (en) * | 1991-09-18 | 2005-08-02 | Kenya Shitara | Process for producing humanized chimera antibody |
JPWO2002078739A1 (en) * | 2001-03-29 | 2004-07-22 | 協和醗酵工業株式会社 | Pharmaceutical containing a recombinant antibody against ganglioside GD3 |
US8946387B2 (en) * | 2002-08-14 | 2015-02-03 | Macrogenics, Inc. | FcγRIIB specific antibodies and methods of use thereof |
-
2009
- 2009-12-01 EP EP09830987A patent/EP2370819A4/en not_active Withdrawn
- 2009-12-01 WO PCT/US2009/066262 patent/WO2010065544A2/en active Application Filing
- 2009-12-01 US US13/132,234 patent/US20110256147A1/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0091005A1 (en) * | 1982-04-02 | 1983-10-12 | Sloan-Kettering Institute For Cancer Research | Method for detecting the presence of GD3 ganglioside |
Non-Patent Citations (4)
Title |
---|
ARIGA TOSHIO ET AL: "Glycosphingolipid antigens in neural tumor cell lines and anti-glycosphingolipid antibodies in sera of patients with neural tumors", NEUROSIGNALS, KARGER, BASEL; CH, vol. 16, no. 2-3, 1 January 2008 (2008-01-01), pages 226 - 234, XP009137122, ISSN: 1424-862X, [retrieved on 20080205], DOI: 10.1159/000111565 * |
GUIDO KOHLA ET AL: "Gangliosides with O-Acetylated Sialic Acids in Tumors of Neuroectodermal Origin", NEUROCHEMICAL RESEARCH, KLUWER ACADEMIC PUBLISHERS-PLENUM PUBLISHERS, NE, vol. 27, no. 7-8, 1 August 2002 (2002-08-01), pages 583 - 592, XP019289512, ISSN: 1573-6903 * |
MEPUR H. RAVINDRANATH ET AL: "Ganglioside GM3:GD3 ratio as an index for the management of melanoma", CANCER, vol. 67, no. 12, 15 June 1991 (1991-06-15), pages 3029 - 3035, XP055034874, ISSN: 0008-543X, DOI: 10.1002/1097-0142(19910615)67:12<3029::AID-CNCR2820671217>3.0.CO;2-8 * |
SCAMBIA G ET AL: "A primary amelanotic melanoma of the vagina diagnosed by immunocytochemistry", INTERNATIONAL JOURNAL OF GYNECOLOGY AND OBSTETRICS, NEW YORK, NY, US, vol. 29, no. 2, 1 June 1989 (1989-06-01), pages 159 - 164, XP026260402, ISSN: 0020-7292, [retrieved on 19890601], DOI: 10.1016/0020-7292(89)90847-3 * |
Also Published As
Publication number | Publication date |
---|---|
WO2010065544A3 (en) | 2010-09-16 |
US20110256147A1 (en) | 2011-10-20 |
WO2010065544A2 (en) | 2010-06-10 |
EP2370819A2 (en) | 2011-10-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20110630 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR |
|
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20120821 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: G01N 33/15 20060101ALI20120814BHEP Ipc: G01N 33/574 20060101ALI20120814BHEP Ipc: G01N 33/50 20060101AFI20120814BHEP Ipc: G01N 33/92 20060101ALI20120814BHEP |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20130319 |