EP2317302A3 - Analyzer and particle imaging method - Google Patents
Analyzer and particle imaging method Download PDFInfo
- Publication number
- EP2317302A3 EP2317302A3 EP10189013.5A EP10189013A EP2317302A3 EP 2317302 A3 EP2317302 A3 EP 2317302A3 EP 10189013 A EP10189013 A EP 10189013A EP 2317302 A3 EP2317302 A3 EP 2317302A3
- Authority
- EP
- European Patent Office
- Prior art keywords
- sample stream
- analyzer
- imaging method
- particle imaging
- light source
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000003384 imaging method Methods 0.000 title abstract 3
- 239000002245 particle Substances 0.000 title abstract 3
- 239000013307 optical fiber Substances 0.000 abstract 2
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1468—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
- G01N15/147—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle the analysis being performed on a sample stream
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1429—Signal processing
- G01N15/1433—Signal processing using image recognition
Landscapes
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Signal Processing (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2009251377A JP2011095181A (en) | 2009-10-30 | 2009-10-30 | Particle analyzer |
Publications (3)
Publication Number | Publication Date |
---|---|
EP2317302A2 EP2317302A2 (en) | 2011-05-04 |
EP2317302A3 true EP2317302A3 (en) | 2017-08-16 |
EP2317302B1 EP2317302B1 (en) | 2019-12-04 |
Family
ID=43480758
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP10189013.5A Active EP2317302B1 (en) | 2009-10-30 | 2010-10-27 | Analyzer and particle imaging method |
Country Status (4)
Country | Link |
---|---|
US (1) | US8675196B2 (en) |
EP (1) | EP2317302B1 (en) |
JP (1) | JP2011095181A (en) |
CN (1) | CN102053056B (en) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2013015357A (en) * | 2011-07-01 | 2013-01-24 | Shimadzu Corp | Flow cytometer |
JP2013195208A (en) * | 2012-03-19 | 2013-09-30 | Sony Corp | Fine particle measuring instrument |
CN102818756B (en) * | 2012-08-03 | 2016-01-20 | 中国科学技术大学 | Based on assay method and the device of the PM2.5 particle of laser energy trapping method |
CN103712927B (en) * | 2012-09-29 | 2016-12-21 | 埃科莱布美国股份有限公司 | Detecting system and method and water treatment system and method |
JP6196502B2 (en) * | 2013-08-30 | 2017-09-13 | シスメックス株式会社 | Sample analysis method and sample analyzer |
US9957554B1 (en) | 2013-12-19 | 2018-05-01 | National Technology & Engineering Solutions Of Sandia, Llc | Microfluidic platform for multiplexed detection in single cells and methods thereof |
DE202014100974U1 (en) * | 2014-03-04 | 2015-06-08 | Retsch Technology Gmbh | Device for determining the particle size and / or the particle shape of a particle mixture |
CN103852409B (en) * | 2014-03-18 | 2016-09-14 | 江西科技师范大学 | The imaging system of hemocyte in flow cytometer |
US9581491B2 (en) | 2014-09-30 | 2017-02-28 | Perkinelmer Health Sciences, Inc. | Flow cell modules and liquid sample analyzers and methods including same |
US9500588B2 (en) * | 2014-09-30 | 2016-11-22 | Perkinelmer Health Sciences, Inc. | Flow cell modules and liquid sample analyzers and methods including same |
US11169126B2 (en) | 2017-02-23 | 2021-11-09 | Phoseon Technology, Inc. | Integrated illumination-detection flow cell for liquid chromatography |
CN115931687A (en) | 2017-03-31 | 2023-04-07 | 生命技术公司 | Apparatus, system and method for imaging flow cytometry |
JP7097718B2 (en) * | 2018-02-27 | 2022-07-08 | シスメックス株式会社 | Particle measuring device and particle measuring method |
CN109443997B (en) * | 2018-12-20 | 2021-03-23 | 常州大学 | Oil pipeline leakage diffusion experiment platform based on photoacoustic tomography |
KR102333898B1 (en) * | 2019-04-09 | 2021-12-01 | 가부시끼가이샤 히다치 세이사꾸쇼 | Particle size measurement apparatus and measurement method |
Citations (5)
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EP0564122A1 (en) * | 1992-04-01 | 1993-10-06 | Toa Medical Electronics Co., Ltd. | Apparatus for analysing particles |
EP1469483A2 (en) * | 2003-04-16 | 2004-10-20 | Shamci Dr. Monajemsbashi | Sample for manipulation by an optical tweezers, and a method and device to generate optically induced forces |
US20060023219A1 (en) * | 2001-03-28 | 2006-02-02 | Meyer Michael G | Optical tomography of small objects using parallel ray illumination and post-specimen optical magnification |
US20080310181A1 (en) * | 2007-06-15 | 2008-12-18 | Microalign Technologies, Inc. | Brightness with reduced optical losses |
US20090161107A1 (en) * | 2004-11-18 | 2009-06-25 | Horiba Abx Sa | Device for examining a fluid by uniform illumination using a configured light guide |
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US3940608A (en) * | 1974-02-04 | 1976-02-24 | Mechanical Technology Incorporated | Fiber optic displacement measuring apparatus |
US4786165A (en) * | 1986-07-10 | 1988-11-22 | Toa Medical Electronics Co., Ltd. | Flow cytometry and apparatus therefor |
JPH06167640A (en) * | 1991-10-03 | 1994-06-14 | Senri Oyo Keisoku Kenkyusho:Kk | Laser light illumination device |
US5416580A (en) * | 1993-07-07 | 1995-05-16 | General Signal Corporation | Methods and apparatus for determining small particle size distribution utilizing multiple light beams |
DE69533469T2 (en) * | 1994-12-26 | 2005-09-22 | Sysmex Corp. | flow cytometer |
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US7603166B2 (en) * | 1996-09-20 | 2009-10-13 | Board Of Regents University Of Texas System | Method and apparatus for detection of vulnerable atherosclerotic plaque |
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WO1999049354A1 (en) * | 1998-03-24 | 1999-09-30 | Sony Corporation | Electrooptic device, driving method thereof, and manufacture thereof |
JP2000266681A (en) * | 1999-03-16 | 2000-09-29 | Kokusai Gijutsu Kaihatsu Kk | Line illumination apparatus |
JP4046446B2 (en) * | 1999-08-31 | 2008-02-13 | シスメックス株式会社 | Particle analyzer |
US6190877B1 (en) * | 1999-12-27 | 2001-02-20 | Edwin L. Adair | Method of cancer screening primarily utilizing non-invasive cell collection and fluorescence detection techniques |
IL138683A0 (en) * | 2000-09-25 | 2001-10-31 | Vital Medical Ltd | Apparatus and method for monitoring tissue vitality parameters |
US7907765B2 (en) * | 2001-03-28 | 2011-03-15 | University Of Washington | Focal plane tracking for optical microtomography |
US6522775B2 (en) * | 2001-03-28 | 2003-02-18 | Alan C. Nelson | Apparatus and method for imaging small objects in a flow stream using optical tomography |
US6519033B1 (en) * | 2001-11-19 | 2003-02-11 | Point Source Technologies, Llc | Identification of particles in fluid |
US20030091277A1 (en) * | 2001-11-15 | 2003-05-15 | Wenhui Mei | Flattened laser scanning system |
JP2003156698A (en) * | 2001-11-22 | 2003-05-30 | Toshiba Corp | Laser light source device |
US20040061853A1 (en) * | 2002-09-27 | 2004-04-01 | Blasenheim Barry J. | Prism-based flow cytometry excitation optics |
KR20060034627A (en) | 2003-03-18 | 2006-04-24 | 캐사로스 메디컬 시스템, 인코포레이티드 | Methods and devices for retrieval of a medical agent from a physiological efferent fluid collection site |
US7471393B2 (en) * | 2004-03-06 | 2008-12-30 | Michael Trainer | Methods and apparatus for determining the size and shape of particles |
JP2008529014A (en) * | 2005-01-31 | 2008-07-31 | ベックマン コールター インコーポレイテッド | Microsphere type photoion sensor using additive-containing silica |
JP4921356B2 (en) * | 2005-03-29 | 2012-04-25 | シスメックス株式会社 | Method and cell analyzer for discriminating cancer / atypical cells and aggregated particles |
JP4756948B2 (en) * | 2005-08-08 | 2011-08-24 | ベイバイオサイエンス株式会社 | Flow cytometer and flow cytometry method |
CN101326428B (en) | 2005-10-11 | 2011-05-18 | 杜克大学 | Systems and method for endoscopic angle-resolved low coherence interferometry |
JP2008111833A (en) * | 2007-10-02 | 2008-05-15 | Toyobo Co Ltd | Apparatus for classifying formed component in urine |
CN101842688B (en) * | 2007-10-29 | 2017-02-08 | 希森美康株式会社 | Cell analysis apparatus and cell analysis method |
CN105181407B (en) * | 2008-03-31 | 2020-06-30 | 希森美康株式会社 | Sample preparation device and sample preparation method, and cell analysis device and cell analysis method |
US7999937B1 (en) * | 2008-05-13 | 2011-08-16 | Sandia Corporation | Microfluidic devices and methods for integrated flow cytometry |
JP5108802B2 (en) * | 2009-02-03 | 2012-12-26 | 富士フイルム株式会社 | Imaging apparatus and through image display method thereof |
-
2009
- 2009-10-30 JP JP2009251377A patent/JP2011095181A/en active Pending
-
2010
- 2010-10-27 EP EP10189013.5A patent/EP2317302B1/en active Active
- 2010-10-28 US US12/914,269 patent/US8675196B2/en active Active
- 2010-10-29 CN CN201010526307.7A patent/CN102053056B/en active Active
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0564122A1 (en) * | 1992-04-01 | 1993-10-06 | Toa Medical Electronics Co., Ltd. | Apparatus for analysing particles |
US20060023219A1 (en) * | 2001-03-28 | 2006-02-02 | Meyer Michael G | Optical tomography of small objects using parallel ray illumination and post-specimen optical magnification |
EP1469483A2 (en) * | 2003-04-16 | 2004-10-20 | Shamci Dr. Monajemsbashi | Sample for manipulation by an optical tweezers, and a method and device to generate optically induced forces |
US20090161107A1 (en) * | 2004-11-18 | 2009-06-25 | Horiba Abx Sa | Device for examining a fluid by uniform illumination using a configured light guide |
US20080310181A1 (en) * | 2007-06-15 | 2008-12-18 | Microalign Technologies, Inc. | Brightness with reduced optical losses |
Also Published As
Publication number | Publication date |
---|---|
JP2011095181A (en) | 2011-05-12 |
US20110102792A1 (en) | 2011-05-05 |
EP2317302B1 (en) | 2019-12-04 |
CN102053056A (en) | 2011-05-11 |
CN102053056B (en) | 2015-04-08 |
EP2317302A2 (en) | 2011-05-04 |
US8675196B2 (en) | 2014-03-18 |
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