EP2313103A4 - Method of treating blepharitis - Google Patents

Method of treating blepharitis

Info

Publication number
EP2313103A4
EP2313103A4 EP09795262A EP09795262A EP2313103A4 EP 2313103 A4 EP2313103 A4 EP 2313103A4 EP 09795262 A EP09795262 A EP 09795262A EP 09795262 A EP09795262 A EP 09795262A EP 2313103 A4 EP2313103 A4 EP 2313103A4
Authority
EP
European Patent Office
Prior art keywords
treating blepharitis
blepharitis
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP09795262A
Other languages
German (de)
French (fr)
Other versions
EP2313103B1 (en
EP2313103A1 (en
Inventor
Kurt E Brubaker
Romulus Kimbro Brazzell
Reza Haque
John C Ice
Jose L Boyer
Joseph B Boyd
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Inspire Pharmaceuticals Inc
Original Assignee
Inspire Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inspire Pharmaceuticals Inc filed Critical Inspire Pharmaceuticals Inc
Publication of EP2313103A1 publication Critical patent/EP2313103A1/en
Publication of EP2313103A4 publication Critical patent/EP2313103A4/en
Application granted granted Critical
Publication of EP2313103B1 publication Critical patent/EP2313103B1/en
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
EP09795262.6A 2008-07-10 2009-07-10 Method of treating blepharitis Not-in-force EP2313103B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7977208P 2008-07-10 2008-07-10
PCT/US2009/050311 WO2010006306A1 (en) 2008-07-10 2009-07-10 Method of treating blepharitis

Publications (3)

Publication Number Publication Date
EP2313103A1 EP2313103A1 (en) 2011-04-27
EP2313103A4 true EP2313103A4 (en) 2012-08-08
EP2313103B1 EP2313103B1 (en) 2014-06-18

Family

ID=41507457

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09795262.6A Not-in-force EP2313103B1 (en) 2008-07-10 2009-07-10 Method of treating blepharitis

Country Status (7)

Country Link
US (1) US8349806B2 (en)
EP (1) EP2313103B1 (en)
JP (2) JP2011527709A (en)
AU (1) AU2009268372B2 (en)
CA (1) CA2730120A1 (en)
MX (1) MX2011000247A (en)
WO (1) WO2010006306A1 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60141525D1 (en) 2000-09-15 2010-04-22 Bruder Healthcare Co WOUND AND TREATMENT COMPRESSION AND ASSOCIATION
US10105259B2 (en) 2000-09-15 2018-10-23 Bruder Healthcare Company, Llc Wound and therapy compress and dressing
US9925087B2 (en) 2000-09-15 2018-03-27 Bruder Healthcare Company, Llc Wound and therapy compress and dressing
CA2730120A1 (en) 2008-07-10 2010-01-14 Inspire Pharmaceuticals, Inc. Method of treating blepharitis
EP2393355A4 (en) * 2009-01-23 2012-07-25 Inspire Pharmaceuticals Inc Method of treating dry eye disease with azithromycin
WO2012092375A1 (en) * 2010-12-29 2012-07-05 Inspire Pharmaceuticals, Inc. Method for treating dry eye
US20130274214A1 (en) * 2010-12-29 2013-10-17 Inspire Pharmaceuticals, Inc. Method for treating blepharitis
CA2840626A1 (en) * 2011-06-29 2013-01-03 Insite Vision Incorporated Methods of treating recurrent meibomian glands disorder and thereby decreasing the frequency of recurrence
WO2013191167A1 (en) * 2012-06-19 2013-12-27 参天製薬株式会社 Method for changing eyelid state of hairless animals
WO2014143139A1 (en) 2013-03-15 2014-09-18 Bruder Healthcare Company Wound and therapy compress and dressing
CN104045674B (en) * 2014-05-21 2017-01-04 丽珠医药集团股份有限公司 A kind of preparation method of azithromycin
CN105106109A (en) * 2015-09-11 2015-12-02 江苏锦宇环境工程有限公司 Method for preparing azithromycin sustained releasing eye drops
WO2017110874A1 (en) * 2015-12-22 2017-06-29 日油株式会社 Lacrimal oily layer stabilizer and eye drops comprising same
US12029681B2 (en) 2016-03-01 2024-07-09 The Hilsinger Company Parent, Llc Therapeutic eye mask system
US12156831B2 (en) 2016-03-01 2024-12-03 The Hilsinger Company Parent, Llc Therapeutic eye compress system
US12011388B2 (en) 2016-03-01 2024-06-18 The Hilsinger Company Parent, Llc Therapeutic thermal compress with phase-change material
US9981041B2 (en) * 2016-08-23 2018-05-29 Ira Jason Salzman Ophthalmic lubricating spray
USD871598S1 (en) 2016-11-30 2019-12-31 Bruder Healthcare Company, Llc Therapeutic eye mask
USD844795S1 (en) 2016-11-30 2019-04-02 Bruder Healthcare Company, Llc Therapeutic eye mask
CN109381707B (en) * 2017-08-03 2022-02-15 沈阳药科大学 Azithromycin ion pair liposome eye drops and preparation method thereof
JP2023133646A (en) * 2020-06-26 2023-09-27 参天製薬株式会社 Lipid secretagogue
EP4247367A4 (en) * 2020-11-23 2024-10-16 Sight Sciences, Inc. FORMULATIONS AND METHODS FOR TREATING EYE CONDITIONS
WO2022180568A1 (en) * 2021-02-25 2022-09-01 Sun Pharmaceutical Industries Limited Dexamethasone for treatment of blepharitis

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1075837A2 (en) * 1999-08-09 2001-02-14 S.I.F.I. Società Industria Farmaceutica Italiana S.p.A. Process for the preparation of aqueous formulations for ophthalmic use

Family Cites Families (24)

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Publication number Priority date Publication date Assignee Title
US6861411B1 (en) 1997-12-02 2005-03-01 Pfizer, Inc. Method of treating eye infections with azithromycin
DE69940227D1 (en) 1998-05-08 2009-02-12 Univ Miami Use of sub-antimicrobial tetracyclines for the treatment of ocular rosacea
US6239113B1 (en) 1999-03-31 2001-05-29 Insite Vision, Incorporated Topical treatment or prevention of ocular infections
US7056893B2 (en) 1999-03-31 2006-06-06 Insite Vision, Inc. Topical treatment for prevention of ocular infections
US7063857B1 (en) 1999-04-30 2006-06-20 Sucampo Ag Use of macrolide compounds for the treatment of dry eye
AR031135A1 (en) 2000-10-10 2003-09-10 Upjohn Co TOPIC ANTIBIOTIC COMPOSITIONS FOR THE TREATMENT OF OCULAR INFECTIONS
HRP20010301A2 (en) 2001-04-27 2001-12-31 Pliva D D New therapeutic indication for azithromycin in the treatment of non-infective inflammatory diseases
WO2004091436A2 (en) 2003-04-15 2004-10-28 The Regents Of The University Of California Methods and compositions for treating ocular disease
US7087237B2 (en) 2003-09-19 2006-08-08 Advanced Ocular Systems Limited Ocular solutions
US20050137205A1 (en) 2003-12-22 2005-06-23 Van Breen Eduard T. Formulation for treating periocular disease
US8425929B2 (en) 2004-04-30 2013-04-23 Allergan, Inc. Sustained release intraocular implants and methods for preventing retinal dysfunction
WO2005110374A1 (en) 2004-04-30 2005-11-24 Allergan, Inc. Intraocular drug delivery systems containing a therapeutic component, a cyclodextrin, and a polymeric component
US8372814B2 (en) 2004-06-07 2013-02-12 Ista Pharmaceuticals, Inc. Ophthalmic formulations and uses thereof
US8349352B2 (en) 2005-02-04 2013-01-08 Auburn University Therapeutic contact lenses with anti-fungal delivery
US8663639B2 (en) 2005-02-09 2014-03-04 Santen Pharmaceutical Co., Ltd. Formulations for treating ocular diseases and conditions
US7247623B2 (en) 2005-08-19 2007-07-24 Inspire Pharmaceuticals, Inc. Method of treating dry eye disease with non-drying antihistamines
US20070225217A1 (en) 2005-11-09 2007-09-27 Combinatorx, Incorporated Methods, compositions, and kits for the treatment of medical conditions
US20070105788A1 (en) 2005-11-09 2007-05-10 Serena Mraz-Gernhard Azithromycin for treatment of granulomatous rosacea
BRPI0707612B8 (en) 2006-02-09 2021-05-25 Macusight Inc sealed vessel and liquid formulations contained therein
SI2049112T1 (en) 2006-08-07 2012-05-31 Bausch & Lomb Treating infections and sequelae thereof with combined dissociated glucocorticoid receptor agonists and anti-infective agents
US11078262B2 (en) 2007-04-30 2021-08-03 Allergan, Inc. High viscosity macromolecular compositions for treating ocular conditions
US20080286338A1 (en) 2007-05-15 2008-11-20 Boston Foundation For Sight Drug delivery system with scleral lens
CA2730120A1 (en) 2008-07-10 2010-01-14 Inspire Pharmaceuticals, Inc. Method of treating blepharitis
EP2393355A4 (en) 2009-01-23 2012-07-25 Inspire Pharmaceuticals Inc Method of treating dry eye disease with azithromycin

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1075837A2 (en) * 1999-08-09 2001-02-14 S.I.F.I. Società Industria Farmaceutica Italiana S.p.A. Process for the preparation of aqueous formulations for ophthalmic use

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JOHN THOMAS ET AL: "Use of azithromycin ophthalmic solution in the treatment of chronic mixed anterior blepharitis.", ANNALS OF OPHTHALMOLOGY (SKOKIE, ILL.) SUMMER 2008 LNKD- PUBMED:19013912, vol. 40, no. 2, 1 July 2008 (2008-07-01), pages 68 - 74, XP009160319, ISSN: 1530-4086 *
See also references of WO2010006306A1 *
SOLOMON, KERRY D: "New Drop Aimed at Lid Margin Disease", 1 April 2008 (2008-04-01), XP002677780, Retrieved from the Internet <URL:http://www.ophthalmologymanagement.com/printarticle.aspx?articleID=101362> [retrieved on 20120612] *

Also Published As

Publication number Publication date
EP2313103B1 (en) 2014-06-18
AU2009268372B2 (en) 2015-06-04
JP2011527709A (en) 2011-11-04
EP2313103A1 (en) 2011-04-27
MX2011000247A (en) 2011-03-30
WO2010006306A1 (en) 2010-01-14
AU2009268372A1 (en) 2010-01-14
JP2014240433A (en) 2014-12-25
CA2730120A1 (en) 2010-01-14
US8349806B2 (en) 2013-01-08
US20100022465A1 (en) 2010-01-28

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