EP2306902A4 - Methods for identifying modulators of ion channels - Google Patents

Methods for identifying modulators of ion channels

Info

Publication number
EP2306902A4
EP2306902A4 EP09794839A EP09794839A EP2306902A4 EP 2306902 A4 EP2306902 A4 EP 2306902A4 EP 09794839 A EP09794839 A EP 09794839A EP 09794839 A EP09794839 A EP 09794839A EP 2306902 A4 EP2306902 A4 EP 2306902A4
Authority
EP
European Patent Office
Prior art keywords
methods
ion channels
identifying modulators
modulators
identifying
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP09794839A
Other languages
German (de)
French (fr)
Other versions
EP2306902A1 (en
Inventor
Lance G Laing
Rick Wagner
Rafael Fernandez
Alexander Yuzakov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
X Body Inc
Original Assignee
SRU Biosystems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US12/171,475 external-priority patent/US9778267B2/en
Priority claimed from US12/335,433 external-priority patent/US9134307B2/en
Application filed by SRU Biosystems Inc filed Critical SRU Biosystems Inc
Publication of EP2306902A1 publication Critical patent/EP2306902A1/en
Publication of EP2306902A4 publication Critical patent/EP2306902A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G01N33/56988—HIV or HTLV
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • AIDS & HIV (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
EP09794839A 2008-07-11 2009-01-08 Methods for identifying modulators of ion channels Withdrawn EP2306902A4 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US12/171,475 US9778267B2 (en) 2007-07-11 2008-07-11 Methods for identifying modulators of ion channels
PCT/US2008/069752 WO2009009718A1 (en) 2007-07-11 2008-07-11 Methods of identifying modulators of ion channels
US12/335,433 US9134307B2 (en) 2007-07-11 2008-12-15 Method for determining ion channel modulating properties of a test reagent
PCT/US2009/030412 WO2010005600A1 (en) 2008-07-11 2009-01-08 Methods for identifying modulators of ion channels

Publications (2)

Publication Number Publication Date
EP2306902A1 EP2306902A1 (en) 2011-04-13
EP2306902A4 true EP2306902A4 (en) 2011-08-10

Family

ID=41507363

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09794839A Withdrawn EP2306902A4 (en) 2008-07-11 2009-01-08 Methods for identifying modulators of ion channels

Country Status (6)

Country Link
EP (1) EP2306902A4 (en)
JP (1) JP2011527573A (en)
CN (1) CN102149327A (en)
AU (1) AU2009269037A1 (en)
CA (1) CA2730415A1 (en)
WO (1) WO2010005600A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8111401B2 (en) 1999-11-05 2012-02-07 Robert Magnusson Guided-mode resonance sensors employing angular, spectral, modal, and polarization diversity for high-precision sensing in compact formats
US7167615B1 (en) 1999-11-05 2007-01-23 Board Of Regents, The University Of Texas System Resonant waveguide-grating filters and sensors and methods for making and using same
US7371562B2 (en) 2000-10-30 2008-05-13 Sru Biosystems, Inc. Guided mode resonant filter biosensor using a linear grating surface structure
US7118710B2 (en) 2000-10-30 2006-10-10 Sru Biosystems, Inc. Label-free high-throughput optical technique for detecting biomolecular interactions
US7575939B2 (en) 2000-10-30 2009-08-18 Sru Biosystems, Inc. Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
US7524625B2 (en) 2000-10-30 2009-04-28 Sru Biosystems, Inc. Real time binding analysis of antigens on a biosensor surface
US7927822B2 (en) 2002-09-09 2011-04-19 Sru Biosystems, Inc. Methods for screening cells and antibodies
US7309614B1 (en) 2002-12-04 2007-12-18 Sru Biosystems, Inc. Self-referencing biodetection method and patterned bioassays
US8298780B2 (en) 2003-09-22 2012-10-30 X-Body, Inc. Methods of detection of changes in cells
CN101802611A (en) * 2007-07-11 2010-08-11 Sru生物系统公司 Differentiate the method for ion channel modulators
US9134307B2 (en) 2007-07-11 2015-09-15 X-Body, Inc. Method for determining ion channel modulating properties of a test reagent
US8257936B2 (en) 2008-04-09 2012-09-04 X-Body Inc. High resolution label free analysis of cellular properties
US20110237535A1 (en) * 2010-03-26 2011-09-29 Sru Biosystems, Inc. Use of Induced Pluripotent Cells and other Cells for Screening Compound Libraries
US9427415B2 (en) * 2014-04-01 2016-08-30 The Procter & Gamble Company Methods and compositions for modifying sensorial perception
CN107596341B (en) * 2017-08-23 2020-08-28 清华大学 L-type voltage-gated calcium channel specific polypeptide agonists and inhibitors

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020028480A1 (en) * 2000-07-10 2002-03-07 Maher Michael P. High throughput method and system for screening candidate compounds for activity against target ion channels
US20040132214A1 (en) * 2000-10-30 2004-07-08 Sru Biosystems, Llc Label-free methods for performing assays using a colorimetric resonant optical biosensor
WO2007064702A1 (en) * 2005-11-30 2007-06-07 Sru Biosystems, Inc. Real time binding analysis of antigens on a biosensor surface
WO2009009718A1 (en) * 2007-07-11 2009-01-15 Sru Biosystems, Inc. Methods of identifying modulators of ion channels
WO2010075033A1 (en) * 2008-12-15 2010-07-01 Sru Biosystems, Inc. Methods of detection of changes in cells

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7575939B2 (en) * 2000-10-30 2009-08-18 Sru Biosystems, Inc. Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
US7927822B2 (en) * 2002-09-09 2011-04-19 Sru Biosystems, Inc. Methods for screening cells and antibodies
WO2007056160A2 (en) * 2005-11-03 2007-05-18 Redpoint Bio Corporation High throughput screening assay for the trpm5 ion channel

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020028480A1 (en) * 2000-07-10 2002-03-07 Maher Michael P. High throughput method and system for screening candidate compounds for activity against target ion channels
US20040191757A1 (en) * 2000-07-10 2004-09-30 Maher Michael P. High throughput method and system for screening candidate compounds for activity against target ion channels
US20040132214A1 (en) * 2000-10-30 2004-07-08 Sru Biosystems, Llc Label-free methods for performing assays using a colorimetric resonant optical biosensor
WO2007064702A1 (en) * 2005-11-30 2007-06-07 Sru Biosystems, Inc. Real time binding analysis of antigens on a biosensor surface
WO2009009718A1 (en) * 2007-07-11 2009-01-15 Sru Biosystems, Inc. Methods of identifying modulators of ion channels
WO2010075033A1 (en) * 2008-12-15 2010-07-01 Sru Biosystems, Inc. Methods of detection of changes in cells

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2010005600A1 *

Also Published As

Publication number Publication date
CA2730415A1 (en) 2010-01-14
JP2011527573A (en) 2011-11-04
EP2306902A1 (en) 2011-04-13
AU2009269037A1 (en) 2010-01-14
CN102149327A (en) 2011-08-10
WO2010005600A1 (en) 2010-01-14

Similar Documents

Publication Publication Date Title
EP2306902A4 (en) Methods for identifying modulators of ion channels
EP2171454A4 (en) Methods of identifying modulators of ion channels
HRP20171454T8 (en) Fused heterocyclic compounds as ion channel modulators
ZA201009128B (en) Heterocyclic derivatives as modulators of ion channels
GB2471637B (en) Interchangeable midsole system
HK1184092A1 (en) Fused heterocyclic compounds as ion channel modulators
EP2283418A4 (en) Multi-channel multi-factor authentication
EP2291200A4 (en) Methods for modulating expression of rbp4
EP2321009B8 (en) Radiotherapy apparatus
GB0813403D0 (en) Potassium ion channel modulators & uses thereof
EP2298042A4 (en) Processes for reconditioning multi-component electrodes
HK1257419A1 (en) Method of identifying risk for thyroid disorder
IL210775A0 (en) Methods of identifying modulators of ubiquitin ligases
EP2087129A4 (en) Method for identifying modulators of the nrf2-keap1-are pathway
GB0805271D0 (en) Encryption method
EP2353000A4 (en) Modulation of an ion channel or receptor
EP2342355A4 (en) Methods of using biomarkers
GB0817576D0 (en) Calcium ion channel modulators & uses thereof
IL210224A0 (en) Calcium ion channels modulators & uses thereof
HK1183516A1 (en) Method for the identification of catechol o-methyltransferase modulators o-
EP2274534A4 (en) Method of identifying positions of brake monitors
EP2229580A4 (en) Method for sample application
EP2252701A4 (en) Methods of identifying an organism
GB0814335D0 (en) Ion channel
GB0819976D0 (en) An encryption method

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20110111

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA RS

A4 Supplementary search report drawn up and despatched

Effective date: 20110708

RIC1 Information provided on ipc code assigned before grant

Ipc: A61B 6/00 20060101AFI20110704BHEP

DAX Request for extension of the european patent (deleted)
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1156490

Country of ref document: HK

RIC1 Information provided on ipc code assigned before grant

Ipc: G01N 33/68 20060101ALI20120605BHEP

Ipc: G01N 33/569 20060101AFI20120605BHEP

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: X-BODY, INC.

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20130801

REG Reference to a national code

Ref country code: HK

Ref legal event code: WD

Ref document number: 1156490

Country of ref document: HK