EP2301525A4 - Topical ibuprofen formulation - Google Patents

Topical ibuprofen formulation

Info

Publication number
EP2301525A4
EP2301525A4 EP09757648A EP09757648A EP2301525A4 EP 2301525 A4 EP2301525 A4 EP 2301525A4 EP 09757648 A EP09757648 A EP 09757648A EP 09757648 A EP09757648 A EP 09757648A EP 2301525 A4 EP2301525 A4 EP 2301525A4
Authority
EP
European Patent Office
Prior art keywords
ibuprofen formulation
topical ibuprofen
topical
formulation
ibuprofen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP09757648A
Other languages
German (de)
French (fr)
Other versions
EP2301525B1 (en
EP2301525A1 (en
Inventor
De Blas Andres Pinilla
Vicente Ana Ortiz
Aguirre Jaime Comin
Ibarra Esther Vaya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LABORATORIOS ALCALA FARMA S.L.
Original Assignee
LABORATORIOS ALCALA FARMA SL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LABORATORIOS ALCALA FARMA SL filed Critical LABORATORIOS ALCALA FARMA SL
Priority to PL09757648T priority Critical patent/PL2301525T3/en
Publication of EP2301525A1 publication Critical patent/EP2301525A1/en
Publication of EP2301525A4 publication Critical patent/EP2301525A4/en
Application granted granted Critical
Publication of EP2301525B1 publication Critical patent/EP2301525B1/en
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EP09757648.2A 2008-06-06 2009-04-30 Topical ibuprofen formulation Not-in-force EP2301525B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL09757648T PL2301525T3 (en) 2008-06-06 2009-04-30 Topical ibuprofen formulation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200801720A ES2330295B1 (en) 2008-06-06 2008-06-06 TOPIC FORMULATION OF IBUPROFEN.
PCT/ES2009/070131 WO2009147269A1 (en) 2008-06-06 2009-04-30 Topical ibuprofen formulation

Publications (3)

Publication Number Publication Date
EP2301525A1 EP2301525A1 (en) 2011-03-30
EP2301525A4 true EP2301525A4 (en) 2013-01-16
EP2301525B1 EP2301525B1 (en) 2013-09-11

Family

ID=41338228

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09757648.2A Not-in-force EP2301525B1 (en) 2008-06-06 2009-04-30 Topical ibuprofen formulation

Country Status (6)

Country Link
US (1) US20090304782A1 (en)
EP (1) EP2301525B1 (en)
ES (1) ES2330295B1 (en)
PL (1) PL2301525T3 (en)
PT (1) PT2301525E (en)
WO (1) WO2009147269A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9504664B2 (en) 2010-10-29 2016-11-29 Infirst Healthcare Limited Compositions and methods for treating severe pain
US9737500B2 (en) 2010-10-29 2017-08-22 Infirst Healthcare Limited Compositions and methods for treating severe pain
US8895537B2 (en) 2010-10-29 2014-11-25 Infirst Healthcare Ltd. Compositions and methods for treating cardiovascular diseases
US10695431B2 (en) 2010-10-29 2020-06-30 Infirst Healthcare Limited Solid solution compositions and use in cardiovascular disease
US11224659B2 (en) 2010-10-29 2022-01-18 Infirst Healthcare Limited Solid solution compositions and use in severe pain
US9308213B2 (en) 2010-10-29 2016-04-12 Infirst Healthcare Limited Solid solution compositions and use in chronic inflammation
US11730709B2 (en) 2010-10-29 2023-08-22 Infirst Healthcare Limited Compositions and methods for treating severe pain
US11202831B2 (en) 2010-10-29 2021-12-21 Infirst Healthcare Limited Solid solution compositions and use in cardiovascular disease
US9271950B2 (en) 2010-10-29 2016-03-01 Infirst Healthcare Limited Compositions for treating chronic inflammation and inflammatory diseases
US10695432B2 (en) 2010-10-29 2020-06-30 Infirst Healthcare Limited Solid solution compositions and use in severe pain
US9744132B2 (en) 2010-10-29 2017-08-29 Infirst Healthcare Limited Solid solution compositions and use in chronic inflammation
CN102579350B (en) * 2012-03-02 2013-04-24 海南灵康制药有限公司 Pidotimod liposome solid preparation
WO2014144365A1 (en) * 2013-03-15 2014-09-18 University Of Maryland, College Park Nano-liposomal formulations and methods of use
US10561627B2 (en) 2014-12-31 2020-02-18 Eric Morrison Ibuprofen nanoparticle carriers encapsulated with hermetic surfactant films
US10596117B1 (en) 2014-12-31 2020-03-24 Eric Morrison Lipoleosomes as carriers for aromatic amide anesthetic compounds
US11007161B1 (en) 2014-12-31 2021-05-18 Eric Morrison Ibuprofen nanoparticle carriers encapsulated with hermatic surfactant films
CN116370428A (en) * 2023-04-28 2023-07-04 济南市中西医结合医院 Ibuprofen sustained release tablet, preparation method and application

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0225162A2 (en) * 1985-11-27 1987-06-10 Ethicon, Inc. Inhibition of post-surgical adhesion formation by the topical administration of non-steroidal anti-inflammatory drug
WO1993025192A1 (en) * 1992-06-12 1993-12-23 Cortecs Limited Pharmaceutical compositions containing nsaid and bile acids

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3421468A1 (en) * 1984-06-08 1985-12-19 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim LIPID NANOPELLETS AS A CARRIER SYSTEM FOR MEDICINAL PRODUCTS FOR PERORAL USE
DE3522550A1 (en) 1985-06-24 1987-01-02 Klinge Co Chem Pharm Fab SPRAYABLE PHARMACEUTICAL PREPARATION FOR TOPICAL APPLICATION
US4877619A (en) * 1986-08-25 1989-10-31 Vestar, Inc. Liposomal vesicles for intraperitoneal administration of therapeutic agents
GB2217596A (en) 1988-04-26 1989-11-01 American Cyanamid Co Anti-arthritic liposome composition
US5036046A (en) 1988-10-12 1991-07-30 Eye Research Institute Of Retina Foundation, Inc. Method for enhancing healing of corneal endothelial wounds
DK0560900T3 (en) 1990-12-03 1995-05-08 Nexstar Pharmaceuticals Inc Prevention of synovial adhesions
WO1994001089A1 (en) 1992-07-08 1994-01-20 Dianorm-Geräte G. Maierhofer Liposomes, method of preparing them and their use in the preparation of drugs
US5785976A (en) * 1993-03-05 1998-07-28 Pharmacia & Upjohn Ab Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof
US5654337A (en) 1995-03-24 1997-08-05 II William Scott Snyder Topical formulation for local delivery of a pharmaceutically active agent
US5827533A (en) * 1997-02-06 1998-10-27 Duke University Liposomes containing active agents aggregated with lipid surfactants
DE19852928C1 (en) * 1998-11-17 2000-08-03 Steffen Panzner Structures in the form of hollow spheres
US20040105881A1 (en) * 2002-10-11 2004-06-03 Gregor Cevc Aggregates with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin
US7132452B2 (en) 2003-03-10 2006-11-07 Fang-Yu Lee Topical formulation having effects on alleviating pain/inflammation caused by herpes virus infection
CA2500907A1 (en) 2005-03-15 2006-09-15 Alpharx Inc. Vehicle for topical delivery of anti-inflammatory compounds
US20060222695A1 (en) * 2005-04-01 2006-10-05 Filiberto Zadini Deoxycholic acid liposome-based dermatological topical preparation
US20080132751A1 (en) * 2006-11-30 2008-06-05 Betazone Laboratories, Inc. Compositions and methods for treatment of pain

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0225162A2 (en) * 1985-11-27 1987-06-10 Ethicon, Inc. Inhibition of post-surgical adhesion formation by the topical administration of non-steroidal anti-inflammatory drug
WO1993025192A1 (en) * 1992-06-12 1993-12-23 Cortecs Limited Pharmaceutical compositions containing nsaid and bile acids

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
A PAAVOLA: "Controlled release injectable liposomal gel of ibuprofen for epidural analgesia", INTERNATIONAL JOURNAL OF PHARMACEUTICS, vol. 199, no. 1, 10 April 2000 (2000-04-10), pages 85 - 93, XP055046709, ISSN: 0378-5173, DOI: 10.1016/S0378-5173(00)00376-8 *
See also references of WO2009147269A1 *
VISHWAKARMA K K ET AL: "In vitro absorption studies of ibuprofen with cholic and deoxycholic acid conjugates", INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 60, no. 3, May 1998 (1998-05-01), pages 149 - 152, XP009165484, ISSN: 0250-474X *

Also Published As

Publication number Publication date
EP2301525B1 (en) 2013-09-11
US20090304782A1 (en) 2009-12-10
ES2330295B1 (en) 2010-09-23
WO2009147269A1 (en) 2009-12-10
PT2301525E (en) 2013-10-16
PL2301525T3 (en) 2014-01-31
EP2301525A1 (en) 2011-03-30
ES2330295A1 (en) 2009-12-07

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Inventor name: COMIN AGUIRRE, JAIME

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