EP2297332A4 - Methods and platforms for drug discovery - Google Patents

Methods and platforms for drug discovery

Info

Publication number
EP2297332A4
EP2297332A4 EP09763772A EP09763772A EP2297332A4 EP 2297332 A4 EP2297332 A4 EP 2297332A4 EP 09763772 A EP09763772 A EP 09763772A EP 09763772 A EP09763772 A EP 09763772A EP 2297332 A4 EP2297332 A4 EP 2297332A4
Authority
EP
European Patent Office
Prior art keywords
platforms
methods
drug discovery
discovery
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP09763772A
Other languages
German (de)
French (fr)
Other versions
EP2297332A2 (en
Inventor
Kazuhiro Sakurada
Kenneth J Seidenman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyoto University NUC
Original Assignee
Kyoto University NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyoto University NUC filed Critical Kyoto University NUC
Publication of EP2297332A2 publication Critical patent/EP2297332A2/en
Publication of EP2297332A4 publication Critical patent/EP2297332A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5073—Stem cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP09763772A 2008-06-13 2009-06-12 Methods and platforms for drug discovery Withdrawn EP2297332A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6159408P 2008-06-13 2008-06-13
US6159208P 2008-06-13 2008-06-13
PCT/US2009/047291 WO2009152484A2 (en) 2008-06-13 2009-06-12 Methods and platforms for drug discovery

Publications (2)

Publication Number Publication Date
EP2297332A2 EP2297332A2 (en) 2011-03-23
EP2297332A4 true EP2297332A4 (en) 2012-03-21

Family

ID=41417418

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09763772A Withdrawn EP2297332A4 (en) 2008-06-13 2009-06-12 Methods and platforms for drug discovery

Country Status (3)

Country Link
EP (1) EP2297332A4 (en)
CN (1) CN102203275A (en)
WO (2) WO2009152484A2 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120171771A1 (en) * 2009-07-08 2012-07-05 Cellular Dynamics International, Inc. Modified ips cells having a mutant form of a human immunodeficiency virus (hiv) cellular entry gene
WO2011119942A1 (en) * 2010-03-25 2011-09-29 Vistagen Therapeutics, Inc. Induction of ips cells using transient episomal vectors
EP2563907B1 (en) 2010-04-28 2019-06-19 The J. David Gladstone Institutes Methods for generating cardiomyocytes
US9228204B2 (en) 2011-02-14 2016-01-05 University Of Utah Research Foundation Constructs for making induced pluripotent stem cells
WO2012116111A1 (en) * 2011-02-22 2012-08-30 Sanford-Burnham Medical Research Institute METHOD AND COMPOUNDS FOR GENERATION OF iPSCs
WO2013033213A1 (en) 2011-08-30 2013-03-07 The J. David Gladstone Institutes Methods for generating cardiomyocytes
JP2018537118A (en) * 2015-10-05 2018-12-20 オリジェン， インコーポレイテッド Diagnosis and treatment of Parkinson's disease based on identification and alleviation of liver dysfunction
CN107603951B (en) * 2016-07-12 2020-08-14 中国人民解放军军事医学科学院基础医学研究所 Novel growth/neurotrophic factor composition for in vivo induction of mature neuronal division and use thereof
GB2583309A (en) * 2017-12-28 2020-10-21 Ibm Neuron model generation for personalised drug treatment
US11227692B2 (en) * 2017-12-28 2022-01-18 International Business Machines Corporation Neuron model simulation
CN109294975A (en) * 2018-10-23 2019-02-01 山东华思生物科技有限公司 A kind of stem cell drugs screening technique
US20220028488A1 (en) * 2018-12-07 2022-01-27 President And Fellows Of Harvard College Drug discovery and early disease identification platform using electronic health records, genetics and stem cells
WO2020129366A1 (en) * 2018-12-21 2020-06-25 アイ ピース， インコーポレイテッド Health risk information management device, health risk information management method, and program
CN111621546A (en) * 2020-06-18 2020-09-04 上海诚益生物科技有限公司 Method for screening thyroxine receptor agonist by using primary hepatocytes

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060222636A1 (en) * 2003-09-19 2006-10-05 The Rockefeller University Compositions, methods and kits relating to reprogramming adult differentiated cells and production of embryonic stem cell-like cells
WO2009061442A1 (en) * 2007-11-06 2009-05-14 Children's Medical Center Corporation Method to produce induced pluripotent stem (ips) cells form non-embryonic human cells

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999010536A1 (en) * 1997-08-22 1999-03-04 Yale University A process to study changes in gene expression in granulocytic cells
US20040048297A1 (en) * 2002-07-30 2004-03-11 Gene Logic, Inc. Nucleic acid detection assay control genes
WO2005095583A1 (en) * 2004-03-03 2005-10-13 Life-Sciences Ag Large scale storage of viable somatic stem and/or progenitor cells
WO2005097190A2 (en) * 2004-03-26 2005-10-20 Celgene Corporation Systems and methods for providing a stem cell bank
US20090074731A1 (en) * 2007-09-13 2009-03-19 Librach Clifford L Method of isolation and use of cells derived from first trimester umbilical cord tissue

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060222636A1 (en) * 2003-09-19 2006-10-05 The Rockefeller University Compositions, methods and kits relating to reprogramming adult differentiated cells and production of embryonic stem cell-like cells
WO2009061442A1 (en) * 2007-11-06 2009-05-14 Children's Medical Center Corporation Method to produce induced pluripotent stem (ips) cells form non-embryonic human cells

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
EBERT ALLISON D ET AL: "Induced pluripotent stem cells from a spinal muscular atrophy patient", NATURE 15 JAN 2009,, vol. 457, no. 7227, 15 January 2009 (2009-01-15), pages 277 - 280, XP002552498, DOI: 10.1038/NATURE07677 *
MALI PRASHANT ET AL: "Improved efficiency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts", STEM CELLS (MIAMISBURG), vol. 26, no. 8, 29 May 2008 (2008-05-29), pages 1998 - 2005, XP002668773, ISSN: 1066-5099 *

Also Published As

Publication number Publication date
EP2297332A2 (en) 2011-03-23
WO2009152485A3 (en) 2010-05-14
CN102203275A (en) 2011-09-28
WO2009152484A2 (en) 2009-12-17
WO2009152485A2 (en) 2009-12-17
WO2009152484A3 (en) 2010-03-11

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20110111

AK Designated contracting states

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Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA RS

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: KYOTO UNIVERSITY

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20120221

RIC1 Information provided on ipc code assigned before grant

Ipc: G01N 33/15 20060101ALI20120213BHEP

Ipc: C12Q 1/02 20060101AFI20120213BHEP

17Q First examination report despatched

Effective date: 20130424

STAA Information on the status of an ep patent application or granted ep patent

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18D Application deemed to be withdrawn

Effective date: 20140924