EP2283137A4 - Recombinant cells and methods for hydroxylating fatty acids - Google Patents

Recombinant cells and methods for hydroxylating fatty acids

Info

Publication number
EP2283137A4
EP2283137A4 EP09734409A EP09734409A EP2283137A4 EP 2283137 A4 EP2283137 A4 EP 2283137A4 EP 09734409 A EP09734409 A EP 09734409A EP 09734409 A EP09734409 A EP 09734409A EP 2283137 A4 EP2283137 A4 EP 2283137A4
Authority
EP
European Patent Office
Prior art keywords
methods
fatty acids
recombinant cells
hydroxylating
hydroxylating fatty
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP09734409A
Other languages
German (de)
French (fr)
Other versions
EP2283137A1 (en
Inventor
Xue-Rong Zhou
Surinder Pal Singh
Allan Green
Anthony Richard Ashton
Andrew John William Rodgers
Geoffrey John Dumsday
Florian Hans Maximilian Graichen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commonwealth Scientific and Industrial Research Organization CSIRO
Grains Research and Development Corp
Original Assignee
Commonwealth Scientific and Industrial Research Organization CSIRO
Grains Research and Development Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commonwealth Scientific and Industrial Research Organization CSIRO, Grains Research and Development Corp filed Critical Commonwealth Scientific and Industrial Research Organization CSIRO
Publication of EP2283137A1 publication Critical patent/EP2283137A1/en
Publication of EP2283137A4 publication Critical patent/EP2283137A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Nutrition Science (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
EP09734409A 2008-04-25 2009-04-24 Recombinant cells and methods for hydroxylating fatty acids Withdrawn EP2283137A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12543708P 2008-04-25 2008-04-25
PCT/AU2009/000518 WO2009129583A1 (en) 2008-04-25 2009-04-24 Recombinant cells and methods for hydroxylating fatty acids

Publications (2)

Publication Number Publication Date
EP2283137A1 EP2283137A1 (en) 2011-02-16
EP2283137A4 true EP2283137A4 (en) 2011-12-14

Family

ID=41216349

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09734409A Withdrawn EP2283137A4 (en) 2008-04-25 2009-04-24 Recombinant cells and methods for hydroxylating fatty acids

Country Status (5)

Country Link
US (1) US20110126325A1 (en)
EP (1) EP2283137A4 (en)
AU (1) AU2009240795B2 (en)
CA (1) CA2722276A1 (en)
WO (1) WO2009129583A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2693630C (en) 2006-07-14 2021-08-31 Commonwealth Scientific And Industrial Research Organisation Altering the fatty acid composition of rice
AU2009240794A1 (en) * 2008-04-25 2009-10-29 Commonwealth Scientific Industrial Research Organisation Polypeptides and methods for producing triacylglycerols comprising modified fatty acids
US11639507B2 (en) 2011-12-27 2023-05-02 Commonwealth Scientific And Industrial Research Organisation Processes for producing lipids
AU2012324024B2 (en) 2011-12-27 2016-06-16 Nuseed Global Innovation Ltd Processes for producing lipids
US8809026B2 (en) 2011-12-27 2014-08-19 Commonwealth Scientific And Industrial Research Organisation Processes for producing lipids
UA116538C2 (en) 2012-04-25 2018-04-10 Коммонвелт Сайнтіфік Енд Індастріел Рісерч Організейшн High oleic acid oils
MX2017000109A (en) 2014-07-07 2017-05-23 Commw Scient Ind Res Org Processes for producing industrial products from plant lipids.
CN107208088B (en) * 2014-12-10 2022-02-11 银杏生物制品公司 Oleic acid production in yeast
CA3035570A1 (en) 2016-09-02 2018-03-08 Commonwealth Scientific And Industrial Research Organisation Plants with modified traits
US11913006B2 (en) 2018-03-16 2024-02-27 Nuseed Global Innovation Ltd. Plants producing modified levels of medium chain fatty acids
CN108753699B (en) * 2018-06-19 2021-04-30 青岛农业大学 Method for remedying in vitro development damage of porcine oocytes by zearalenone
AU2022276006A1 (en) * 2021-05-20 2023-12-14 Berkeley Fermentation Science Inc. Methods and compositions for gamma-decalactone biosynthesis in fermented beverages

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060107345A1 (en) * 2003-09-30 2006-05-18 Nickolai Alexandrov Sequence-determined DNA fragments and corresponding polypeptides encoded thereby

Family Cites Families (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0131623B2 (en) 1983-01-17 1999-07-28 Monsanto Company Chimeric genes suitable for expression in plant cells
US5504200A (en) 1983-04-15 1996-04-02 Mycogen Plant Science, Inc. Plant gene expression
US4945050A (en) * 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US5420034A (en) * 1986-07-31 1995-05-30 Calgene, Inc. Seed-specific transcriptional regulation
US5188958A (en) 1986-05-29 1993-02-23 Calgene, Inc. Transformation and foreign gene expression in brassica species
US5177010A (en) * 1986-06-30 1993-01-05 University Of Toledo Process for transforming corn and the products thereof
SE455438B (en) 1986-11-24 1988-07-11 Aga Ab SET TO REDUCE A BURNER'S FLAME TEMPERATURE AND BURNER WITH THE OXYGEN RESP FUEL NOZZLE
US5004863B2 (en) 1986-12-03 2000-10-17 Agracetus Genetic engineering of cotton plants and lines
US5416011A (en) * 1988-07-22 1995-05-16 Monsanto Company Method for soybean transformation and regeneration
US5932479A (en) 1988-09-26 1999-08-03 Auburn University Genetic engineering of plant chloroplasts
US5034323A (en) 1989-03-30 1991-07-23 Dna Plant Technology Corporation Genetic engineering of novel plant phenotypes
US5141131A (en) * 1989-06-30 1992-08-25 Dowelanco Method and apparatus for the acceleration of a propellable matter
EP0472712B1 (en) 1990-03-16 2001-09-12 Calgene LLC Novel sequences preferentially expressed in early seed development and methods related thereto
US5877402A (en) * 1990-05-01 1999-03-02 Rutgers, The State University Of New Jersey DNA constructs and methods for stably transforming plastids of multicellular plants and expressing recombinant proteins therein
US5451513A (en) 1990-05-01 1995-09-19 The State University of New Jersey Rutgers Method for stably transforming plastids of multicellular plants
US5384253A (en) * 1990-12-28 1995-01-24 Dekalb Genetics Corporation Genetic transformation of maize cells by electroporation of cells pretreated with pectin degrading enzymes
US5518908A (en) 1991-09-23 1996-05-21 Monsanto Company Method of controlling insects
US5593874A (en) * 1992-03-19 1997-01-14 Monsanto Company Enhanced expression in plants
DE69410247T2 (en) * 1993-03-11 1998-09-03 Canada Nat Res Council IMPROVED CEREAL REGENERATION SYSTEM
CA2092588C (en) 1993-03-26 2008-07-08 Narender S. Nehra Enhanced regeneration system for cereals
US5362865A (en) 1993-09-02 1994-11-08 Monsanto Company Enhanced expression in plants using non-translated leader sequences
GB9324707D0 (en) 1993-12-02 1994-01-19 Olsen Odd Arne Promoter
GB9403512D0 (en) 1994-02-24 1994-04-13 Olsen Odd Arne Promoter
US5545818A (en) 1994-03-11 1996-08-13 Calgene Inc. Expression of Bacillus thuringiensis cry proteins in plant plastids
GB9524938D0 (en) 1995-12-06 1996-02-07 Zeneca Ltd Modification of starch synthesis in plants
US6027900A (en) * 1996-04-12 2000-02-22 Carnegie Institution Of Washington Methods and tools for transformation of eukaryotic algae
US5977436A (en) 1997-04-09 1999-11-02 Rhone Poulenc Agrochimie Oleosin 5' regulatory region for the modification of plant seed lipid composition
US6235529B1 (en) 1997-04-29 2001-05-22 The Regents Of The University Of California Compositions and methods for plant transformation and regeneration
WO1999005265A2 (en) 1997-07-23 1999-02-04 Sanford Scientific, Inc. Improved plastid transformation of higher plants and production of transgenic plants with herbicide resistance
NZ503137A (en) 1997-09-12 2000-10-27 Groupe Limagrain Pacific Pty L Sequence and promoters for starch branching enzyme I, starch branching enzyme II, soluble starch synthase I and starch debranching enzyme derived from Triticum tauschii to modulate gene expression
EP1019517B2 (en) 1997-09-30 2014-05-21 The Regents of The University of California Production of proteins in plant seeds
US6100447A (en) * 1998-02-12 2000-08-08 Applied Phytologics, Inc. Method of barley transformation
DE19950589A1 (en) * 1999-10-20 2001-05-23 Gvs Ges Fuer Erwerb Und Verwer Elongase promoters for tissue-specific expression of transgenes in plants
US8202979B2 (en) * 2002-02-20 2012-06-19 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid
US20110131679A2 (en) 2000-04-19 2011-06-02 Thomas La Rosa Rice Nucleic Acid Molecules and Other Molecules Associated with Plants and Uses Thereof for Plant Improvement
US6540987B2 (en) * 2001-03-15 2003-04-01 Ethox Chemicals Llc Polyesters based on hydroxy fatty acids and lower hydroxy alkyl acids and uses thereof
JP2005185101A (en) * 2002-05-30 2005-07-14 National Institute Of Agrobiological Sciences VEGETABLE FULL-LENGTH cDNA AND UTILIZATION THEREOF
US20060150283A1 (en) 2004-02-13 2006-07-06 Nickolai Alexandrov Sequence-determined DNA fragments and corresponding polypeptides encoded thereby
EP2302062A1 (en) 2003-10-20 2011-03-30 CropDesign N.V. Identification of E2F target genes and uses thereof
CN102559364B (en) * 2004-04-22 2016-08-17 联邦科学技术研究组织 Use recombinant cell synthesis of long-chain polyunsaturated fatty acids
US7834250B2 (en) * 2004-04-22 2010-11-16 Commonwealth Scientific And Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
CA2661697A1 (en) * 2006-08-29 2008-03-06 Commonwealth Scientific And Industrial Research Organisation Synthesis of fatty acids
EP2358882B1 (en) * 2008-11-18 2017-07-26 Commonwealth Scientific and Industrial Research Organisation Enzymes and methods for producing omega-3 fatty acids
US9311457B1 (en) 2011-11-02 2016-04-12 Google Inc. Platform for cloud application software
US8946460B2 (en) * 2012-06-15 2015-02-03 Commonwealth Scientific And Industrial Research Organisation Process for producing polyunsaturated fatty acids in an esterified form

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060107345A1 (en) * 2003-09-30 2006-05-18 Nickolai Alexandrov Sequence-determined DNA fragments and corresponding polypeptides encoded thereby

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
ALEMANY REGINA ET AL: "2-Hydroxyoleic acid: A new hypotensive molecule.", February 2004, HYPERTENSION (BALTIMORE), VOL. 43, NR. 2, ISSN: 0194-911X, pages: 249 - 254 *
BEY MELANIE ET AL: "Characterization of Antirrhinum petal development and identification of target genes of the class B MADS box gene DEFICIENS", December 2004, PLANT CELL, VOL. 16, NR. 12, PAGE(S) 3197-3215, ISSN: 1040-4651, XP002660270 *
DATABASE EM_EST [online] 7 December 2004 (2004-12-07), XP002660271, Database accession no. AJ808692 *
DATABASE Swiss-Prot [online] 31 October 2006 (2006-10-31), XP002660269, Database accession no. Q9SUC5 *
ECKHARDT MATTHIAS ET AL: "A mammalian fatty acid hydroxylase responsible for the formation of alpha-hydroxylated galactosylceramide in myelin", May 2005, BIOCHEMICAL JOURNAL, VOL. 388, NR. PART 1, PAGE(S) 245-254, ISSN: 0264-6021, XP009152494 *
ORHAN ILKAY ET AL: "Quantification of daidzein, genistein and fatty acids in soybeans and soy sprouts, and some bioactivity studies", 2007, ACTA BIOLOGICA CRACOVIENSIA SERIES BOTANICA, VOL. 49, NR. 2, ISSN: 0001-5296 *
See also references of WO2009129583A1 *

Also Published As

Publication number Publication date
EP2283137A1 (en) 2011-02-16
CA2722276A1 (en) 2009-10-29
AU2009240795B2 (en) 2014-03-20
AU2009240795A1 (en) 2009-10-29
US20110126325A1 (en) 2011-05-26
WO2009129583A1 (en) 2009-10-29

Similar Documents

Publication Publication Date Title
EP2283137A4 (en) Recombinant cells and methods for hydroxylating fatty acids
ZA201008170B (en) Polypeptides and methods for producing triacyglycerols comprising modified fatty acids
EP2358882A4 (en) Enzymes and methods for producing omega-3 fatty acids
HK1214163A1 (en) Beta amino ester compounds and uses thereof
EP2041047A4 (en) Fatty acid blends and uses therefor
EP2445340A4 (en) Substituted hydroxamic acids and uses thereof
PL2509461T3 (en) Lip balm with spherical surface and method for producing
EP2280442A4 (en) Fuel cell and method for diassembling the same
HK1173120A1 (en) Vessel and method for making the same
EP2338201A4 (en) Advanced materials and design for low temperature sofcs
EP2509432A4 (en) High diglyceride structuring composition and products and methods using the same
PL2391620T3 (en) Alkylamine-substituted dicyanopyridine and amino acid ester prodrugs thereof
EP2459189A4 (en) Fatty acids as anti-inflammatory agents
HK1173968A1 (en) Stabilized liquid and lyophilized adamts13 formulations adamts13
EP2385826A4 (en) Methods and materials for delivering bile acids
EP2234994A4 (en) Alkylester fatty acid blends and uses therefor
ZA201201063B (en) Novel fatty acid desaturases and elongases and uses thereof
PL2239336T3 (en) Microorganism for producing l-amino acids and method for producing l-amino acids using same
PL2121558T3 (en) Method for preparing fatty acid esters with alcohol recycling
SG10201405455UA (en) Cells and methods for obtaining them
EP2405005A4 (en) Microorganism which produces l-amino acid and method for producing l-amino acid using the same
PL2281030T3 (en) Method for inducing and accelerating cells
EP2405006A4 (en) Microorganism which produces l-amino acid and method for producing l-amino acid using the same
EP2416427A4 (en) Fuel cell system and operating method thereof
EP2441111A4 (en) Fuel cell device and method of operating the same

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20101125

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA RS

REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1148553

Country of ref document: HK

RIC1 Information provided on ipc code assigned before grant

Ipc: C12N 15/81 20060101AFI20111006BHEP

Ipc: C11C 3/00 20060101ALI20111006BHEP

Ipc: C11B 1/00 20060101ALI20111006BHEP

Ipc: C12N 15/82 20060101ALI20111006BHEP

Ipc: C12N 9/02 20060101ALI20111006BHEP

A4 Supplementary search report drawn up and despatched

Effective date: 20111115

RIC1 Information provided on ipc code assigned before grant

Ipc: C12N 15/81 20060101AFI20111109BHEP

Ipc: C12N 9/02 20060101ALI20111109BHEP

Ipc: C11B 1/00 20060101ALI20111109BHEP

Ipc: C11C 3/00 20060101ALI20111109BHEP

Ipc: C12N 15/82 20060101ALI20111109BHEP

17Q First examination report despatched

Effective date: 20140227

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

INTG Intention to grant announced

Effective date: 20160108

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20160519

REG Reference to a national code

Ref country code: HK

Ref legal event code: WD

Ref document number: 1148553

Country of ref document: HK