EP2260302A4 - Imaging mass spectrometry for improved prostate cancer diagnostics - Google Patents

Imaging mass spectrometry for improved prostate cancer diagnostics

Info

Publication number
EP2260302A4
EP2260302A4 EP09762988A EP09762988A EP2260302A4 EP 2260302 A4 EP2260302 A4 EP 2260302A4 EP 09762988 A EP09762988 A EP 09762988A EP 09762988 A EP09762988 A EP 09762988A EP 2260302 A4 EP2260302 A4 EP 2260302A4
Authority
EP
European Patent Office
Prior art keywords
mass spectrometry
prostate cancer
imaging mass
cancer diagnostics
improved prostate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP09762988A
Other languages
German (de)
French (fr)
Other versions
EP2260302A2 (en
Inventor
O John Semmes
Lisa H Cazares
Richard R Drake
Savvas Mendrinos
Raymond S Lance
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eastern Virginia Medical School
Original Assignee
Eastern Virginia Medical School
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eastern Virginia Medical School filed Critical Eastern Virginia Medical School
Publication of EP2260302A2 publication Critical patent/EP2260302A2/en
Publication of EP2260302A4 publication Critical patent/EP2260302A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57434—Specifically defined cancers of prostate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/91—Transferases (2.)
    • G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • G01N2333/91205—Phosphotransferases in general
    • G01N2333/9121—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/56—Staging of a disease; Further complications associated with the disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP09762988A 2008-03-14 2009-03-13 Imaging mass spectrometry for improved prostate cancer diagnostics Withdrawn EP2260302A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3683708P 2008-03-14 2008-03-14
PCT/US2009/037110 WO2009151693A2 (en) 2008-03-14 2009-03-13 Imaging mass spectrometry for improved prostate cancer diagnostics

Publications (2)

Publication Number Publication Date
EP2260302A2 EP2260302A2 (en) 2010-12-15
EP2260302A4 true EP2260302A4 (en) 2011-09-28

Family

ID=41417314

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09762988A Withdrawn EP2260302A4 (en) 2008-03-14 2009-03-13 Imaging mass spectrometry for improved prostate cancer diagnostics

Country Status (6)

Country Link
US (1) US20110136166A1 (en)
EP (1) EP2260302A4 (en)
JP (1) JP2011519413A (en)
AU (1) AU2009258038A1 (en)
CA (1) CA2714956A1 (en)
WO (1) WO2009151693A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2013267976B2 (en) * 2012-05-29 2016-06-02 Biodesix, Inc. Deep-MALDI TOF mass spectrometry of complex biological samples, e.g., serum, and uses thereof
EP2700949A1 (en) * 2012-08-24 2014-02-26 IMG Institut für medizinische Genomforschung Planungsgesellschaft M.B.H. Use of biliverdin reductase proteins as cancer marker
MY202410A (en) 2017-09-01 2024-04-27 Venn Biosciences Corp Identification and use of glycopeptides as biomarkers for diagnosis and treatment monitoring
JP2022517827A (en) * 2019-01-22 2022-03-10 イマビオテク Methods for assessing molecular changes associated with molecular effects in biological samples
CN114199980B (en) * 2021-11-08 2024-02-20 岛津企业管理（中国）有限公司 Lung cancer typing judgment system based on mass spectrum imaging technology

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070009970A1 (en) * 2005-07-08 2007-01-11 Predicant Biosciences, Inc. Biological patterns for diagnosis and treatment of cancer

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4366241A (en) * 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US4517288A (en) 1981-01-23 1985-05-14 American Hospital Supply Corp. Solid phase system for ligand assay
CA1291031C (en) 1985-12-23 1991-10-22 Nikolaas C.J. De Jaeger Method for the detection of specific binding agents and their correspondingbindable substances
US5808300A (en) 1996-05-10 1998-09-15 Board Of Regents, The University Of Texas System Method and apparatus for imaging biological samples with MALDI MS
US5972615A (en) * 1998-01-21 1999-10-26 Urocor, Inc. Biomarkers and targets for diagnosis, prognosis and management of prostate disease
WO2005056825A1 (en) * 2003-12-05 2005-06-23 Board Of Regents, The University Of Texas System Screening for modulators of mekk2 and mekk3
EP1894013A2 (en) * 2005-06-08 2008-03-05 Vanderbilt University Analysis of tissue samples surrounding malignancies

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070009970A1 (en) * 2005-07-08 2007-01-11 Predicant Biosciences, Inc. Biological patterns for diagnosis and treatment of cancer

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CAZARES L H ET AL: "MALDI-MSI (Mass spectometry imaging) discriminates malignant and nonmalignant disease of the prostate and identifies specific protein markers", MODERN PATHOLOGY, vol. 21, no. Suppl. 1, January 2008 (2008-01-01), & 97TH ANNUAL MEETING OF THE UNITED-STATES-AND-CANADIAN-ACADEMY-OF-PATH OLOGY; DENVER, CO, USA; MARCH 01 -07, 2008, pages 150A, XP008141202, ISSN: 0893-3952 *
L. H. CAZARES ET AL: "Imaging Mass Spectrometry of a Specific Fragment of Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase Kinase 2 Discriminates Cancer from Uninvolved Prostate Tissue", CLINICAL CANCER RESEARCH, vol. 15, no. 17, 1 September 2009 (2009-09-01), pages 5541 - 5551, XP055004975, ISSN: 1078-0432, DOI: 10.1158/1078-0432.CCR-08-2892 *
See also references of WO2009151693A2 *

Also Published As

Publication number Publication date
US20110136166A1 (en) 2011-06-09
AU2009258038A1 (en) 2009-12-17
EP2260302A2 (en) 2010-12-15
WO2009151693A3 (en) 2010-05-20
CA2714956A1 (en) 2009-12-17
WO2009151693A2 (en) 2009-12-17
JP2011519413A (en) 2011-07-07

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