EP2205723A1 - Verfahren zur initiierung der kardiomyozyten-differenzierung - Google Patents

Verfahren zur initiierung der kardiomyozyten-differenzierung

Info

Publication number
EP2205723A1
EP2205723A1 EP08756942A EP08756942A EP2205723A1 EP 2205723 A1 EP2205723 A1 EP 2205723A1 EP 08756942 A EP08756942 A EP 08756942A EP 08756942 A EP08756942 A EP 08756942A EP 2205723 A1 EP2205723 A1 EP 2205723A1
Authority
EP
European Patent Office
Prior art keywords
cells
csx
protein
stem cells
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP08756942A
Other languages
English (en)
French (fr)
Inventor
Mark Alexander Kirkland
Liem Thanh Vo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cytomatrix Pty Ltd
Original Assignee
Cytomatrix Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2007903204A external-priority patent/AU2007903204A0/en
Application filed by Cytomatrix Pty Ltd filed Critical Cytomatrix Pty Ltd
Publication of EP2205723A1 publication Critical patent/EP2205723A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657—Cardiomyocytes; Heart cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
EP08756942A 2007-06-14 2008-06-13 Verfahren zur initiierung der kardiomyozyten-differenzierung Withdrawn EP2205723A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2007903204A AU2007903204A0 (en) 2007-06-14 Methods
PCT/AU2008/000862 WO2008151387A1 (en) 2007-06-14 2008-06-13 Method of initiating cardiomyocyte differentiation

Publications (1)

Publication Number Publication Date
EP2205723A1 true EP2205723A1 (de) 2010-07-14

Family

ID=40129149

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08756942A Withdrawn EP2205723A1 (de) 2007-06-14 2008-06-13 Verfahren zur initiierung der kardiomyozyten-differenzierung

Country Status (3)

Country Link
EP (1) EP2205723A1 (de)
AU (1) AU2008261550A1 (de)
WO (1) WO2008151387A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9517250B2 (en) 2010-04-28 2016-12-13 The J. David Gladstone Institutes Methods for generating cardiomyocytes
WO2013033213A1 (en) 2011-08-30 2013-03-07 The J. David Gladstone Institutes Methods for generating cardiomyocytes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU770384B2 (en) * 1998-05-30 2004-02-19 Collateral Therapeutics, Inc. Methods of altering cardiac cell phenotype
WO2004019767A2 (en) * 2002-08-29 2004-03-11 Baylor College Of Medicine Heart derived cells for cardiac repair

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO2008151387A1 *

Also Published As

Publication number Publication date
WO2008151387A1 (en) 2008-12-18
AU2008261550A1 (en) 2008-12-18

Similar Documents

Publication Publication Date Title
US20110190730A1 (en) Methods of inducing pluripotency involving oct4 protein
US20110190729A1 (en) Methods of inducing pluripotency involving sox2 protein
Yoshida et al. Maturation of human induced pluripotent stem cell-derived cardiomyocytes by soluble factors from human mesenchymal stem cells
Song et al. Transfection of mesenchymal stem cells with the FGF-2 gene improves their survival under hypoxic conditions
JP5684963B2 (ja) 筋肉由来前駆細胞、その組成物、および治療法を使用した軟部組織および骨の増大および肥厚
US20210145893A1 (en) Compositions to amplify cardiac stem cells in vitro and in viv
SG177467A1 (en) Pre-natal mesenchymal stem cells
WO2009027563A1 (es) Población de células madre adultas derivadas de tejido adiposo cardiaco y su uso en regeneración cardiaca
US20100209404A1 (en) Enhanced method for producing stem-like cells from somatic cells
Goerke et al. Human endothelial progenitor cells induce extracellular signal-regulated kinase-dependent differentiation of mesenchymal stem cells into smooth muscle cells upon cocultivation
JP5395672B2 (ja) 心臓病理学を処置するための筋肉由来の細胞およびその作製法および使用法
US20200345851A1 (en) Epicardial-derived paracrine factors for repairing cardiac tissue
Hamdi et al. Efficacy of epicardially delivered adipose stroma cell sheets in dilated cardiomyopathy
US20180071341A1 (en) Bone augmentation utilizing muscle-derived progenitor compositions, and treatments thereof
EP2205723A1 (de) Verfahren zur initiierung der kardiomyozyten-differenzierung
JP7165979B2 (ja) 骨格筋細胞及びその誘導方法
US20230212570A1 (en) Cell-penetrating peptide-microrna conjugates for intracellular cell delivery
WO2008151388A1 (en) Methods of initiating insulin production
JP5687059B2 (ja) 筋肉誘導前駆体組成物を利用した骨格筋の強化およびその処置
Tanaka et al. The synthetic peptide SVVYGLR promotes cell motility of myogenic cells and facilitates differentiation in skeletal muscle regeneration
US20110223138A1 (en) Mesenchymal stem cells that express increased amounts of anti-apoptotic proteins
JP2022026709A (ja) ＴＧＦ－βを含む組織の線維化抑制剤

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20100423

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA MK RS

DAX Request for extension of the european patent (deleted)
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN

18W Application withdrawn

Effective date: 20110117