EP2157179A4 - Glycerol-3-phosphate acyltransferase (gpat) homologs and use thereof - Google Patents

Glycerol-3-phosphate acyltransferase (gpat) homologs and use thereof

Info

Publication number
EP2157179A4
EP2157179A4 EP08765533A EP08765533A EP2157179A4 EP 2157179 A4 EP2157179 A4 EP 2157179A4 EP 08765533 A EP08765533 A EP 08765533A EP 08765533 A EP08765533 A EP 08765533A EP 2157179 A4 EP2157179 A4 EP 2157179A4
Authority
EP
European Patent Office
Prior art keywords
gpat
homologs
glycerol
phosphate acyltransferase
acyltransferase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP08765533A
Other languages
German (de)
French (fr)
Other versions
EP2157179A1 (en
EP2157179B1 (en
Inventor
Misa Ochiai
Hisanori Tokuda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suntory Holdings Ltd
Original Assignee
Suntory Holdings Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suntory Holdings Ltd filed Critical Suntory Holdings Ltd
Publication of EP2157179A1 publication Critical patent/EP2157179A1/en
Publication of EP2157179A4 publication Critical patent/EP2157179A4/en
Application granted granted Critical
Publication of EP2157179B1 publication Critical patent/EP2157179B1/en
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • A—HUMAN NECESSITIES
    • A21—BAKING; EDIBLE DOUGHS
    • A21D—TREATMENT, e.g. PRESERVATION, OF FLOUR OR DOUGH, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS; PRESERVATION THEREOF
    • A21D8/00—Methods for preparing or baking dough
    • A21D8/02—Methods for preparing dough; Treating dough prior to baking
    • A21D8/04—Methods for preparing dough; Treating dough prior to baking treating dough with microorganisms or enzymes
    • A21D8/042—Methods for preparing dough; Treating dough prior to baking treating dough with microorganisms or enzymes with enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
    • A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/189—Enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Polymers & Plastics (AREA)
  • Biomedical Technology (AREA)
  • Food Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Nutrition Science (AREA)
  • Animal Husbandry (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
EP08765533.8A 2007-06-18 2008-06-12 Glycerol-3-phosphate acyltransferase (gpat) homologs and use thereof Not-in-force EP2157179B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007160042 2007-06-18
PCT/JP2008/060789 WO2008156026A1 (en) 2007-06-18 2008-06-12 Glycerol-3-phosphate acyltransferase (gpat) homologue and use thereof

Publications (3)

Publication Number Publication Date
EP2157179A1 EP2157179A1 (en) 2010-02-24
EP2157179A4 true EP2157179A4 (en) 2011-11-23
EP2157179B1 EP2157179B1 (en) 2014-05-07

Family

ID=40156183

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08765533.8A Not-in-force EP2157179B1 (en) 2007-06-18 2008-06-12 Glycerol-3-phosphate acyltransferase (gpat) homologs and use thereof

Country Status (11)

Country Link
US (1) US8247209B2 (en)
EP (1) EP2157179B1 (en)
JP (1) JP5451387B2 (en)
KR (1) KR101496805B1 (en)
CN (1) CN101578366B (en)
AU (1) AU2008264603B2 (en)
BR (1) BRPI0809911A2 (en)
CA (1) CA2685713C (en)
DK (1) DK2157179T3 (en)
RU (1) RU2485179C2 (en)
WO (1) WO2008156026A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2172548B1 (en) * 2007-07-11 2016-12-21 Suntory Holdings Limited Phosphatidic acid phosphatase homologs and use thereof
BRPI1013611A8 (en) * 2009-03-18 2015-12-15 Suntory Holdings Ltd acetylco carboxylase
KR101399242B1 (en) 2009-09-18 2014-05-27 산토리 홀딩스 가부시키가이샤 Glycerol-3-phosphate acyl transferase
KR101438981B1 (en) * 2009-12-21 2014-09-11 산토리 홀딩스 가부시키가이샤 Diacylglycerole acyltransferase gene, and use thereof
BR112012019566A2 (en) * 2010-02-03 2015-09-15 Suntory Holdings Ltd glycerol 3-phosphate acyltransferase homologue and use thereof
US9181568B2 (en) 2012-04-23 2015-11-10 Exxonmobil Research And Engineering Company Cell systems and methods for improving fatty acid synthesis by expression of dehydrogenases
CN111748566A (en) * 2020-07-02 2020-10-09 山东农业大学 Cultivated peanut AhGPAT9A gene and application thereof in improving oil content of seeds

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060115881A1 (en) * 2004-11-04 2006-06-01 Damude Howard G High eicosapentaenoic acid producing strains of Yarrowia lipolytica

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4149007B2 (en) 1995-02-01 2008-09-10 麒麟麦酒株式会社 DNA molecule for determining aggregation of yeast and determination method of aggregation
EP0843007A4 (en) * 1995-07-27 2002-04-17 Kirin Brewery Dna strands encoding glycerol-3-phosphate acyltransferase
JP4231170B2 (en) 1999-10-26 2009-02-25 サントリー株式会社 Yeast breeding method
WO2001040514A1 (en) 1999-11-30 2001-06-07 Asahi Breweries, Ltd Method of judging flocculating properties of bottom brewer's yeast
AU2004225838B2 (en) 2003-03-31 2009-11-05 University Of Bristol Novel plant acyltransferases specific for long-chained, multiply unsaturated fatty acids
WO2005019437A1 (en) 2003-08-22 2005-03-03 Suntory Limited Method of breeding lipid-producing fungus
US7192762B2 (en) * 2004-11-04 2007-03-20 E. I. Du Pont De Nemours And Company Mortierella alpina glycerol-3-phosphate o-acyltransferase for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms
US7448575B2 (en) * 2005-02-28 2008-11-11 Ip Venture, Inc. Comfortable seating arrangements with easy access
US7470532B2 (en) * 2005-10-19 2008-12-30 E.I. Du Pont De Nemours And Company Mortierella alpina C16/18 fatty acid elongase
JP2007160042A (en) 2005-12-13 2007-06-28 Takehiko Tada Numeral piece and game board set

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060115881A1 (en) * 2004-11-04 2006-06-01 Damude Howard G High eicosapentaenoic acid producing strains of Yarrowia lipolytica

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE UniProt [online] 1 June 1994 (1994-06-01), "RecName: Full=Glycerol-3-phosphate O-acyltransferase 2; Short=G-3-P acyltransferase 2; EC=2.3.1.15; AltName: Full=Dihydroxyacetone phosphate acyltransferase 2; Short=DHAP-AT 2; EC=2.3.1.42; AltName: Full=Glycerol-3-phosphate / dihydroxyacetone phosphate acyltransferase 2;", XP002660986, retrieved from EBI accession no. UNIPROT:P36148 Database accession no. P36148 *
DATABASE UniProt [online] 12 June 2007 (2007-06-12), "SubName: Full=Glycerol-3-phosphate O-acyltransferase 1;", XP002660987, retrieved from EBI accession no. UNIPROT:A5DXQ4 Database accession no. A5DXQ4 *
DATABASE UniProt [online] 26 February 2008 (2008-02-26), "SubName: Full=Predicted protein;", XP002660985, retrieved from EBI accession no. UNIPROT:B0D0X4 Database accession no. B0D0X4 *
See also references of WO2008156026A1 *

Also Published As

Publication number Publication date
US20100159110A1 (en) 2010-06-24
BRPI0809911A2 (en) 2014-10-07
CN101578366A (en) 2009-11-11
JPWO2008156026A1 (en) 2010-08-26
RU2485179C2 (en) 2013-06-20
WO2008156026A1 (en) 2008-12-24
AU2008264603A8 (en) 2010-01-21
CN101578366B (en) 2012-05-30
DK2157179T3 (en) 2014-06-10
AU2008264603B2 (en) 2013-05-02
EP2157179A1 (en) 2010-02-24
KR101496805B1 (en) 2015-03-02
JP5451387B2 (en) 2014-03-26
AU2008264603A1 (en) 2008-12-24
EP2157179B1 (en) 2014-05-07
CA2685713A1 (en) 2008-12-24
RU2010101208A (en) 2011-07-27
US8247209B2 (en) 2012-08-21
KR20100024383A (en) 2010-03-05
CA2685713C (en) 2015-03-31

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