EP2145903A4 - Separating agent for optical isomer - Google Patents

Separating agent for optical isomer

Info

Publication number
EP2145903A4
EP2145903A4 EP08752326A EP08752326A EP2145903A4 EP 2145903 A4 EP2145903 A4 EP 2145903A4 EP 08752326 A EP08752326 A EP 08752326A EP 08752326 A EP08752326 A EP 08752326A EP 2145903 A4 EP2145903 A4 EP 2145903A4
Authority
EP
European Patent Office
Prior art keywords
optical isomer
separating agent
separating
agent
isomer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP08752326A
Other languages
German (de)
French (fr)
Other versions
EP2145903B1 (en
EP2145903A1 (en
Inventor
Yoshio Okamoto
Chiyo Yamamoto
Tomoyuki Ikai
Masami Kamigaito
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nagoya University NUC
Daicel Corp
Original Assignee
Nagoya University NUC
Daicel Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nagoya University NUC, Daicel Chemical Industries Ltd filed Critical Nagoya University NUC
Publication of EP2145903A1 publication Critical patent/EP2145903A1/en
Publication of EP2145903A4 publication Critical patent/EP2145903A4/en
Application granted granted Critical
Publication of EP2145903B1 publication Critical patent/EP2145903B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B3/00—Preparation of cellulose esters of organic acids
    • C08B3/14—Preparation of cellulose esters of organic acids in which the organic acid residue contains substituents, e.g. NH2, Cl
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/265—Synthetic macromolecular compounds modified or post-treated polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B01J20/285—Porous sorbents based on polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/29—Chiral phases
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B15/00—Preparation of other cellulose derivatives or modified cellulose, e.g. complexes
    • C08B15/05—Derivatives containing elements other than carbon, hydrogen, oxygen, halogens or sulfur
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B33/00—Preparation of derivatives of amylose
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B33/00—Preparation of derivatives of amylose
    • C08B33/02—Esters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EP08752326.2A 2007-05-07 2008-05-02 Separating agent for optical isomer Active EP2145903B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007122843 2007-05-07
PCT/JP2008/058421 WO2008136512A1 (en) 2007-05-07 2008-05-02 Separating agent for optical isomer

Publications (3)

Publication Number Publication Date
EP2145903A1 EP2145903A1 (en) 2010-01-20
EP2145903A4 true EP2145903A4 (en) 2012-06-06
EP2145903B1 EP2145903B1 (en) 2014-08-20

Family

ID=39943616

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08752326.2A Active EP2145903B1 (en) 2007-05-07 2008-05-02 Separating agent for optical isomer

Country Status (6)

Country Link
US (2) US20100099861A1 (en)
EP (1) EP2145903B1 (en)
JP (1) JP5531288B2 (en)
KR (1) KR20100017644A (en)
CN (1) CN101679529B (en)
WO (1) WO2008136512A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100303878A1 (en) * 2009-06-02 2010-12-02 Joram Slager Biodegradable bioactive agent releasing matrices with particulates
CA2763522A1 (en) * 2009-06-02 2010-12-09 Surmodics, Inc. Silane-functionalized hydrophobic .alpha.(1.fwdarw.-4)glucopyranose polymers and polymeric matrices for implantation or injection
US8586731B2 (en) * 2009-06-11 2013-11-19 Surmodics, Inc. Hydrophobic polysaccharides with diester- or carbonate ester-containing linkages having enhanced degradation
US20120149851A1 (en) * 2009-08-26 2012-06-14 Eiji Yashima Separating agent for optical isomers
US8932616B2 (en) * 2009-09-30 2015-01-13 Surmodics, Inc. Hydrophobic polysaccharides with silyl ether linkages having enhanced degradation and medical articles made therefrom
US8568760B2 (en) * 2009-12-30 2013-10-29 Surmodics, Inc. Hydrophobic polysaccharides with pendent groups having terminal reactive functionalities and medical uses thereof
JP6016631B2 (en) * 2010-06-18 2016-10-26 株式会社ダイセル Separating agent for optical isomers
CN102311504B (en) * 2010-07-09 2017-05-10 株式会社大赛璐 polysaccharide derivative and preparation method thereof and separating agent
EP2848932B1 (en) * 2012-05-10 2018-08-22 National University Corporation Nagoya University Separating agent for optical isomer
CN110642767B (en) * 2019-09-20 2021-07-09 武汉远大弘元股份有限公司 Separation and purification method of acetylcysteine enantiomer

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5811532A (en) * 1997-06-30 1998-09-22 Uop Llc Covalently bound, polysaccharide-based chiral stationary phases
US20020058763A1 (en) * 1998-09-11 2002-05-16 Institut Francais Du Petrole Chloro-, hydroxy- and alkoxysilane derivatives of polysaccharides or oligosaccharides, polymerizable and cross-linkable, their synthesis and their use as sources of novel support materials
US20040262229A1 (en) * 2003-05-30 2004-12-30 Yoshio Okamoto Separating agent for optical isomers, method of production thereof, and separation column for optical isomers

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0691956B2 (en) 1981-03-11 1994-11-16 ダイセル化学工業株式会社 Adsorbent for separation supporting optically active polymer
USRE38435E1 (en) * 1983-12-28 2004-02-24 Daicel Chemical Industries, Ltd. Separating agent
USRE34457E (en) * 1983-12-28 1993-11-30 Daicel Chemical Industries, Inc. Separating agent
JPS60142930A (en) 1983-12-28 1985-07-29 Daicel Chem Ind Ltd Resolving agent
US4912205A (en) * 1986-03-20 1990-03-27 Daicel Chemical Industries, Ltd. Alkyl-substituted phenylcarbamate derivative of polysaccharide
US4861872A (en) * 1986-03-20 1989-08-29 Daicel Chemical Industries, Ltd. Alkyl-phenylcarbamate derivative of polysaccharide
JPH0813844B2 (en) 1986-03-20 1996-02-14 ダイセル化学工業株式会社 Alkyl-substituted phenylcarbamate derivatives of polysaccharides
JP3181349B2 (en) 1991-03-04 2001-07-03 ダイセル化学工業株式会社 Polysaccharide derivative, method for producing the same, and separating agent
WO1992015635A1 (en) * 1991-03-04 1992-09-17 Daicel Chemical Industries, Ltd. Polysaccharide derivative, production thereof, and separating agent
FR2784108A1 (en) 1998-09-11 2000-04-07 Inst Francais Du Petrole NEW CROSS-LINKED POLYMERS BASED ON BIS-SILANE DERIVATIVES, BIS-THIOETHERS, BIS-SULFOXIDES, BIS-SULPHONES AND BUTANE DI-YL FROM POLYSACCHARIDES AND OLIGOSACCHARIDES, AND THEIR FORMATION INTO SUPPORTED MATERIALS
FR2784109B1 (en) 1998-09-11 2003-09-26 Inst Francais Du Petrole CHLORO-, HYDROXY-, AND ALKOXYSILAN DERIVATIVES OF POLYSACCHARIDES OR OLIGOSACCHARIDES, POLYMERIZABLE AND CROSS-LINKABLE, THEIR SYNTHESIS AND THEIR USE AS SOURCES OF NEW SUPPORTED MATERIALS
JP2001029282A (en) * 1999-07-19 2001-02-06 Toshiba Tec Corp Vacuum cleaner and its suction port
JP2002052814A (en) * 2000-08-11 2002-02-19 Canon Inc Light-transmitting recording medium for ink jet recording
JPWO2002030853A1 (en) * 2000-10-13 2004-02-19 ダイセル化学工業株式会社 Filler for separating optical isomers and method for separating optical isomers using the same
CN1774292B (en) * 2003-03-26 2012-02-22 大赛璐化学工业株式会社 Separating agent for chromatography and process for producing the same
CN1929911A (en) * 2004-03-04 2007-03-14 大赛璐化学工业株式会社 Separating agent for optical isomer
JP5540368B2 (en) * 2006-05-09 2014-07-02 国立大学法人名古屋大学 Filler for optical isomer separation
WO2010036344A2 (en) * 2008-09-24 2010-04-01 Grace Gmbh & Co. Kg Compositions, oral care products and methods of making and using the same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5811532A (en) * 1997-06-30 1998-09-22 Uop Llc Covalently bound, polysaccharide-based chiral stationary phases
US20020058763A1 (en) * 1998-09-11 2002-05-16 Institut Francais Du Petrole Chloro-, hydroxy- and alkoxysilane derivatives of polysaccharides or oligosaccharides, polymerizable and cross-linkable, their synthesis and their use as sources of novel support materials
US20040262229A1 (en) * 2003-05-30 2004-12-30 Yoshio Okamoto Separating agent for optical isomers, method of production thereof, and separation column for optical isomers

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CHEN X ET AL: "Synthesis of covalently bonded cellulose derivative chiral stationary phases with a bifunctional reagent of 3-(triethoxysilyl)propyl isocyanate", JOURNAL OF CHROMATOGRAPHY, ELSEVIER SCIENCE PUBLISHERS B.V, NL, vol. 1010, no. 2, 29 August 2003 (2003-08-29), pages 185 - 194, XP004447873, ISSN: 0021-9673, DOI: 10.1016/S0021-9673(03)01104-X *
QIN FENG ET AL: "Improved procedure for preparation of covalently bonded cellulose tris-phenylcarbamate chiral stationary phases", CHINESE JOURNAL OF CHEMISTRY, ZHONGGUO KEXUEYUAN, CN, vol. 23, no. 7, 1 January 2005 (2005-01-01), pages 885 - 890, XP002554215, ISSN: 1001-604X *
See also references of WO2008136512A1 *

Also Published As

Publication number Publication date
EP2145903B1 (en) 2014-08-20
JPWO2008136512A1 (en) 2010-07-29
WO2008136512A1 (en) 2008-11-13
US10836834B2 (en) 2020-11-17
KR20100017644A (en) 2010-02-16
JP5531288B2 (en) 2014-06-25
US20160326267A1 (en) 2016-11-10
CN101679529A (en) 2010-03-24
US20100099861A1 (en) 2010-04-22
CN101679529B (en) 2012-10-10
EP2145903A1 (en) 2010-01-20

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